Detailed information for compound 1274794

Basic information

Technical information
  • TDR Targets ID: 1274794
  • Name: N-(1,5-dimethyl-3-oxo-2-phenylpyrazol-4-yl)-5 -furan-2-yl-7-(trifluoromethyl)pyrazolo[1,5-a ]pyrimidine-3-carboxamide
  • MW: 482.415 | Formula: C23H17F3N6O3
  • H donors: 1 H acceptors: 4 LogP: 3.12 Rotable bonds: 6
    Rule of 5 violations (Lipinski): 1
  • SMILES: O=C(c1cnn2c1nc(cc2C(F)(F)F)c1ccco1)Nc1c(C)n(n(c1=O)c1ccccc1)C
  • InChi: 1S/C23H17F3N6O3/c1-13-19(22(34)32(30(13)2)14-7-4-3-5-8-14)29-21(33)15-12-27-31-18(23(24,25)26)11-16(28-20(15)31)17-9-6-10-35-17/h3-12H,1-2H3,(H,29,33)
  • InChiKey: APVISUILTKFCCB-UHFFFAOYSA-N  

Network

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Synonyms

  • N-(1,5-dimethyl-3-oxo-2-phenyl-pyrazol-4-yl)-5-(2-furyl)-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine-3-carboxamide
  • N-(1,5-dimethyl-3-oxo-2-phenyl-4-pyrazolyl)-5-(2-furyl)-7-(trifluoromethyl)-3-pyrazolo[1,5-a]pyrimidinecarboxamide
  • 5-(2-furyl)-N-(3-keto-1,5-dimethyl-2-phenyl-pyrazol-4-yl)-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine-3-carboxamide
  • N-(1,5-dimethyl-3-oxo-2-phenyl-pyrazol-4-yl)-5-furan-2-yl-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine-3-carboxamide
  • BAS 00924033
  • ZINC00845073
  • ChemDiv1_012614
  • MLS000109863
  • MLS000910816
  • SMR000105798
  • STK343030

Targets

Known targets for this compound

Species Target name Source Bibliographic reference
Homo sapiens muscleblind-like splicing regulator 1 Starlite/ChEMBL No references
Schistosoma mansoni Thioredoxin glutathione reductase Starlite/ChEMBL No references
Homo sapiens ATM serine/threonine kinase Starlite/ChEMBL No references
Homo sapiens ATPase family, AAA domain containing 5 Starlite/ChEMBL No references

Predicted pathogen targets for this compound

By orthology
Species Potential target Known druggable target/s Ortholog Group
Echinococcus multilocularis muscleblind protein 1 Get druggable targets OG5_132352 All targets in OG5_132352
Schistosoma japonicum hypothetical protein Get druggable targets OG5_128955 All targets in OG5_128955
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein Get druggable targets OG5_128955 All targets in OG5_128955
Candida albicans similar to putative phosphatidylinositol kinase involved in telomere length regulation Get druggable targets OG5_128955 All targets in OG5_128955
Leishmania mexicana trypanothione reductase Get druggable targets OG5_126785 All targets in OG5_126785
Echinococcus granulosus thioredoxin glutathione reductase Get druggable targets OG5_126785 All targets in OG5_126785
Candida albicans similar to S. cerevisiae GLR1 (YPL091W) glutathione oxidoreductase Get druggable targets OG5_126785 All targets in OG5_126785
Trypanosoma cruzi trypanothione reductase, putative Get druggable targets OG5_126785 All targets in OG5_126785
Plasmodium berghei thioredoxin reductase, putative Get druggable targets OG5_126785 All targets in OG5_126785
Leishmania braziliensis phosphatidylinositol kinase related protein, putative Get druggable targets OG5_128955 All targets in OG5_128955
Mycobacterium tuberculosis NADPH-dependent mycothiol reductase Mtr Get druggable targets OG5_126785 All targets in OG5_126785
Trypanosoma cruzi phosphatidylinositol kinase related protein, putative Get druggable targets OG5_128955 All targets in OG5_128955
Leishmania infantum phosphatidylinositol kinase related protein, putative Get druggable targets OG5_128955 All targets in OG5_128955
Trypanosoma cruzi phosphatidylinositol kinase related protein, putative Get druggable targets OG5_128955 All targets in OG5_128955
Plasmodium berghei glutathione reductase, putative Get druggable targets OG5_126785 All targets in OG5_126785
Schistosoma japonicum ko:K00384 thioredoxin reductase (NADPH) [EC1.8.1.9], putative Get druggable targets OG5_126785 All targets in OG5_126785
Plasmodium yoelii thioredoxin reductase Get druggable targets OG5_126785 All targets in OG5_126785
Leishmania donovani trypanothione reductase Get druggable targets OG5_126785 All targets in OG5_126785
Theileria parva thioredoxin reductase, putative Get druggable targets OG5_126785 All targets in OG5_126785
Brugia malayi Thioredoxin reductase Get druggable targets OG5_126785 All targets in OG5_126785
Leishmania major trypanothione reductase Get druggable targets OG5_126785 All targets in OG5_126785
Loa Loa (eye worm) thioredoxin reductase Get druggable targets OG5_126785 All targets in OG5_126785
Plasmodium falciparum thioredoxin reductase Get druggable targets OG5_126785 All targets in OG5_126785
Echinococcus multilocularis muscleblind protein Get druggable targets OG5_132352 All targets in OG5_132352
Candida albicans similar to S. cerevisiae GLR1 (YPL091W) glutathione oxidoreductase Get druggable targets OG5_126785 All targets in OG5_126785
Neospora caninum MGC84926 protein, related Get druggable targets OG5_126785 All targets in OG5_126785
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_128955 All targets in OG5_128955
Plasmodium vivax glutathione reductase, putative Get druggable targets OG5_126785 All targets in OG5_126785
Trypanosoma brucei gambiense trypanothione reductase, putative Get druggable targets OG5_126785 All targets in OG5_126785
Schistosoma japonicum ko:K04728 ataxia telangectasia mutated family protein, putative Get druggable targets OG5_128955 All targets in OG5_128955
Candida albicans identical to the C terminus of CaP19.5580 potential phosphatidylinositol kinase Get druggable targets OG5_128955 All targets in OG5_128955
Neospora caninum Glutathione reductase, related Get druggable targets OG5_126785 All targets in OG5_126785
Echinococcus multilocularis atpase aaa+ type core atpase aaa type core Get druggable targets OG5_139225 All targets in OG5_139225
Trypanosoma brucei phosphatidylinositol kinase related protein, putative Get druggable targets OG5_128955 All targets in OG5_128955
Trichomonas vaginalis PIKK family atypical protein kinase Get druggable targets OG5_128955 All targets in OG5_128955
Neospora caninum phosphatidylinositol 3- and 4-kinase domain- containing protein, putative Get druggable targets OG5_128955 All targets in OG5_128955
Toxoplasma gondii thioredoxin reductase Get druggable targets OG5_126785 All targets in OG5_126785
Echinococcus granulosus serine protein kinase ATM Get druggable targets OG5_128955 All targets in OG5_128955
Brugia malayi Muscleblind-like protein Get druggable targets OG5_132352 All targets in OG5_132352
Leishmania major phosphatidylinositol kinase related protein, putative Get druggable targets OG5_128955 All targets in OG5_128955
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_132352 All targets in OG5_132352
Echinococcus multilocularis serine protein kinase ATM Get druggable targets OG5_128955 All targets in OG5_128955
Leishmania infantum trypanothione reductase Get druggable targets OG5_126785 All targets in OG5_126785
Trypanosoma brucei trypanothione reductase Get druggable targets OG5_126785 All targets in OG5_126785
Echinococcus granulosus muscleblind protein Get druggable targets OG5_132352 All targets in OG5_132352
Loa Loa (eye worm) glutathione reductase Get druggable targets OG5_126785 All targets in OG5_126785
Cryptosporidium hominis thioredoxin reductase Get druggable targets OG5_126785 All targets in OG5_126785
Candida albicans similar to putative phosphatidylinositol kinase involved in telomere length regulation Get druggable targets OG5_128955 All targets in OG5_128955
Plasmodium knowlesi thioredoxin reductase, putative Get druggable targets OG5_126785 All targets in OG5_126785
Plasmodium vivax thioredoxin reductase, putative Get druggable targets OG5_126785 All targets in OG5_126785
Schistosoma japonicum hypothetical protein Get druggable targets OG5_128955 All targets in OG5_128955
Cryptosporidium parvum thioredoxin reductase 1 Get druggable targets OG5_126785 All targets in OG5_126785
Babesia bovis thiodoxin reductase, putative Get druggable targets OG5_126785 All targets in OG5_126785
Trypanosoma brucei gambiense phosphatidylinositol kinase domain protein, putative Get druggable targets OG5_128955 All targets in OG5_128955
Brugia malayi glutathione reductase Get druggable targets OG5_126785 All targets in OG5_126785
Plasmodium falciparum glutathione reductase Get druggable targets OG5_126785 All targets in OG5_126785
Trypanosoma cruzi phosphatidylinositol kinase related protein, putative Get druggable targets OG5_128955 All targets in OG5_128955
Plasmodium yoelii glutathione reductase Get druggable targets OG5_126785 All targets in OG5_126785
Trypanosoma congolense trypanothione reductase, putative Get druggable targets OG5_126785 All targets in OG5_126785
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_132352 All targets in OG5_132352
Entamoeba histolytica hypothetical protein Get druggable targets OG5_128955 All targets in OG5_128955
Toxoplasma gondii FATC domain-containing protein Get druggable targets OG5_128955 All targets in OG5_128955
Leishmania mexicana phosphatidylinositol 3-kinase-like protein Get druggable targets OG5_128955 All targets in OG5_128955
Leishmania braziliensis trypanothione reductase Get druggable targets OG5_126785 All targets in OG5_126785
Plasmodium knowlesi glutathione reductase, putative Get druggable targets OG5_126785 All targets in OG5_126785
Echinococcus multilocularis thioredoxin glutathione reductase Get druggable targets OG5_126785 All targets in OG5_126785
Schistosoma mansoni ataxia telangiectasia mutated (atm) Get druggable targets OG5_128955 All targets in OG5_128955
Schistosoma japonicum IPR000971,Globin;IPR012292,Globin-related;IPR009050,Globin-like,domain-containing Get druggable targets OG5_128955 All targets in OG5_128955
Leishmania donovani phosphatidylinositol 3-kinase-like protein Get druggable targets OG5_128955 All targets in OG5_128955

By sequence similarity to non orthologous known druggable targets
Species Potential target Known druggable target Length Alignment span Identity
Neospora caninum glutathione reductase, putative Thioredoxin glutathione reductase   598 aa 532 aa 34.6 %
Neospora caninum Dihydrolipoyl dehydrogenase (EC 1.8.1.4), related Thioredoxin glutathione reductase   598 aa 512 aa 28.3 %
Plasmodium berghei dihydrolipoyl dehydrogenase, apicoplast, putative Thioredoxin glutathione reductase   598 aa 538 aa 25.3 %
Neospora caninum hypothetical protein Thioredoxin glutathione reductase   598 aa 485 aa 30.5 %
Onchocerca volvulus Thioredoxin glutathione reductase   598 aa 533 aa 50.8 %
Plasmodium vivax dihydrolipoyl dehydrogenase, apicoplast, putative Thioredoxin glutathione reductase   598 aa 521 aa 21.5 %
Plasmodium knowlesi dihydrolipoyl dehydrogenase, apicoplast, putative Thioredoxin glutathione reductase   598 aa 518 aa 22.0 %
Plasmodium yoelii dihydrolipoamide dehydrogenase Thioredoxin glutathione reductase   598 aa 537 aa 24.2 %
Toxoplasma gondii NADPH-glutathione reductase Thioredoxin glutathione reductase   598 aa 555 aa 33.5 %
Plasmodium falciparum dihydrolipoyl dehydrogenase, apicoplast Thioredoxin glutathione reductase   598 aa 513 aa 25.0 %

Obtained from network model

Ranking Plot


Putative Targets List


Species Potential target Raw Global Species
Giardia lamblia GTOR 0.0065 0.0361 0.0824
Loa Loa (eye worm) melatonin receptor type 1A 0.0054 0.0278 0.0453
Echinococcus granulosus dihydropyrimidine dehydrogenase NADP 0.0109 0.0678 0.0678
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0019 0.0025 0.0041
Echinococcus multilocularis 0.0054 0.0279 0.0279
Brugia malayi Carboxylesterase family protein 0.0083 0.049 0.0798
Echinococcus granulosus transcription factor Dp 1 0.0039 0.0169 0.0169
Mycobacterium tuberculosis Probable shortchain dehydrogenase 0.0019 0.0025 0.0014
Echinococcus multilocularis uncharacterized sodium dependent transporter 0.0025 0.0064 0.0064
Echinococcus granulosus allatostatin A receptor 0.0054 0.0278 0.0278
Trichomonas vaginalis PIKK family atypical protein kinase 0.0036 0.0149 0.0199
Onchocerca volvulus 0.0025 0.0064 0.0077
Trypanosoma cruzi short chain dehydrogenase, putative 0.0019 0.0025 0.0015
Schistosoma mansoni ubiquitously transcribed sex (X/Y) chromosome tetratricopeptide repeat protein-related 0.0025 0.007 0.0066
Echinococcus granulosus tm gpcr rhodopsin 0.0054 0.0278 0.0278
Chlamydia trachomatis dihydrolipoyl dehydrogenase 0.0409 0.2878 1
Brugia malayi NADPH:adrenodoxin oxidoreductase, mitochondrial precursor 0.0109 0.0678 0.1104
Echinococcus multilocularis atpase aaa+ type core atpase aaa type core 0.0979 0.705 0.705
Mycobacterium tuberculosis Probable oxidoreductase 0.0019 0.0025 0.0014
Schistosoma mansoni biogenic amine receptor 0.0054 0.0278 0.0274
Plasmodium falciparum ataxin-2 like protein, putative 0.0074 0.0424 0.1006
Echinococcus granulosus retinol dehydrogenase 11 0.0019 0.0025 0.0025
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0123 0.078 0.1872
Toxoplasma gondii carbonyl reductase 1, putative 0.0019 0.0025 0.0036
Brugia malayi Pyridine nucleotide-disulphide oxidoreductase family protein 0.0109 0.0678 0.1104
Loa Loa (eye worm) hypothetical protein 0.0052 0.026 0.0424
Trichomonas vaginalis phosphofructokinase, putative 0.003 0.01 0.0128
Loa Loa (eye worm) jmjC domain-containing protein 0.0025 0.007 0.0113
Trypanosoma brucei phosphatidylinositol kinase related protein, putative 0.0038 0.0163 0.015
Onchocerca volvulus Neuropeptide F receptor homolog 0.0054 0.0278 0.0383
Brugia malayi Pre-SET motif family protein 0.0123 0.078 0.1271
Brugia malayi Calcitonin receptor-like protein seb-1 0.0098 0.0603 0.0982
Toxoplasma gondii Sodium:neurotransmitter symporter family protein 0.0025 0.0064 0.0132
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0147 0.0959 0.1357
Toxoplasma gondii 3-ketoacyl-CoA reductase, putative 0.0019 0.0025 0.0036
Echinococcus granulosus lamin 0.0052 0.0267 0.0267
Brugia malayi latrophilin 2 splice variant baaae 0.0067 0.0375 0.0611
Entamoeba histolytica hypothetical protein 0.0038 0.0163 0.0366
Schistosoma mansoni transient receptor potential channel 0.0075 0.0435 0.0432
Loa Loa (eye worm) hypothetical protein 0.0054 0.0278 0.0453
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0021 0.0033 0.0054
Trichomonas vaginalis PIKK family atypical protein kinase 0.0056 0.0296 0.0408
Brugia malayi Cyclic-nucleotide gated cation channel 0.0021 0.0033 0.0054
Onchocerca volvulus 0.0054 0.0278 0.0383
Mycobacterium leprae putative cytochrome p450 0.0054 0.0279 0.0502
Leishmania major target of rapamycin (TOR) kinase 1, putative 0.0065 0.0361 0.0363
Trichomonas vaginalis adenylate cyclase, type VII, putative 0.0025 0.0067 0.0081
Echinococcus granulosus nuclear factor of activated T cells 5 0.0143 0.0932 0.0932
Entamoeba histolytica FKBP-rapamycin associated protein (FRAP), putative 0.0065 0.0361 0.0841
Leishmania major hypothetical protein, conserved 0.0019 0.0025 0.0015
Echinococcus granulosus neuropeptide receptor 0.0054 0.0278 0.0278
Trypanosoma brucei pyridine nucleotide-disulphide oxidoreductase, putative 0.0109 0.0678 0.0684
Giardia lamblia Thioredoxin reductase 0.0109 0.0678 0.1587
Schistosoma mansoni steroid dehydrogenase 0.0019 0.0025 0.0021
Echinococcus multilocularis hyperpolarization activated cyclic 0.0021 0.0033 0.0033
Plasmodium falciparum conserved Plasmodium protein, unknown function 0.0019 0.0025 0.0036
Schistosoma mansoni peptide (allatostatin/somatostatin)-like receptor 0.0054 0.0278 0.0274
Leishmania major cytochrome p450-like protein 0.0054 0.0279 0.0278
Brugia malayi alpha keto acid dehydrogenase complex, E3 component, lipoamide dehydrogenase 0.0301 0.2083 0.3392
Loa Loa (eye worm) hypothetical protein 0.0019 0.0025 0.0041
Brugia malayi Voltage-gated potassium channel, EAG (KCNH1)-related. C. elegans egl-2 ortholog 0.0024 0.0058 0.0094
Schistosoma mansoni hypothetical protein 0.0054 0.0278 0.0274
Brugia malayi jmjC domain containing protein 0.0025 0.007 0.0113
Onchocerca volvulus 0.0196 0.1316 0.1867
Leishmania major cathepsin L-like protease 0.0066 0.0368 0.037
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0019 0.0025 0.0041
Onchocerca volvulus Dopamine\/Ecdysteroid receptor homolog 0.0054 0.0278 0.0383
Trypanosoma cruzi tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0068 0.0377 0.038
Schistosoma mansoni hypothetical protein 0.0054 0.0278 0.0274
Onchocerca volvulus 0.0025 0.0064 0.0077
Mycobacterium ulcerans NADH dehydrogenase Ndh1 0.0109 0.0678 0.2308
Plasmodium vivax ferrodoxin reductase, putative 0.0109 0.0678 0.1623
Mycobacterium ulcerans cytochrome P450 191A3 Cyp191A3 0.0054 0.0279 0.0913
Echinococcus granulosus cytochrome P450 2K1 0.0054 0.0279 0.0279
Mycobacterium tuberculosis Probable NADH-dependent glutamate synthase (small subunit) GltD (L-glutamate synthase) (L-glutamate synthetase) (NADH-glutamate 0.0109 0.0678 0.1303
Leishmania major tyrosyl-DNA phosphodiesterase 1 0.0068 0.0377 0.038
Mycobacterium ulcerans short chain dehydrogenase 0.0019 0.0025 0.0025
Trypanosoma cruzi short chain dehydrogenase/reductase, putative 0.0019 0.0025 0.0015
Echinococcus granulosus potassium voltage gated channel subfamily H 0.005 0.0245 0.0245
Treponema pallidum diphosphate--fructose-6-phosphate 1-phosphotransferase 0.003 0.01 0.0197
Schistosoma mansoni neuropeptide receptor 0.0054 0.0278 0.0274
Echinococcus multilocularis dro:myosuppressin receptor 0.0054 0.0278 0.0278
Mycobacterium leprae Probable NADH-dependent glutamate synthase (small subunit) GltD (L-glutamate synthase) (L-glutamate synthetase) (NADH-glutamate 0.0109 0.0678 0.129
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0054 0.0278 0.0278
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0054 0.0278 0.0274
Mycobacterium tuberculosis Probable oxidoreductase 0.0711 0.5084 1
Schistosoma mansoni hypothetical protein 0.0028 0.0088 0.0084
Onchocerca volvulus 0.0109 0.0678 0.0954
Echinococcus granulosus rhodopsin orphan GPCR 0.0054 0.0278 0.0278
Schistosoma mansoni biogenic amine (octopamine/dopamine) receptor 0.0054 0.0278 0.0274
Trichomonas vaginalis ap endonuclease, putative 0.0018 0.0018 0.0011
Treponema pallidum diphosphate--fructose-6-phosphate 1-phosphotransferase 0.011 0.0685 0.1606
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0066 0.0368 0.0363
Leishmania major short chain dehydrogenase/reductase, putative 0.0019 0.0025 0.0015
Mycobacterium tuberculosis Decaprenylphosphoryl-D-2-keto erythro pentose reductase 0.0019 0.0025 0.0014
Brugia malayi Unidentified vitellogenin-linked transcript protein 6, putative 0.0054 0.0278 0.0453
Plasmodium falciparum LCCL domain-containing protein 0.016 0.1055 0.254
Trypanosoma cruzi C-8 sterol isomerase, putative 0.0356 0.2487 0.2563
Trypanosoma cruzi 3-keto-dihydrosphingosine reductase 0.0019 0.0025 0.0015
Echinococcus granulosus g protein coupled receptor 0.0054 0.0278 0.0278
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0409 0.2878 0.2968
Echinococcus granulosus glutamate synthase 0.0109 0.0678 0.0678
Schistosoma mansoni voltage-gated potassium channel 0.0021 0.0033 0.0029
Mycobacterium tuberculosis Inositol-1-monophosphatase SuhB 0.0132 0.0846 0.1635
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0019 0.0025 0.0041
Echinococcus granulosus potassium voltage gated channel subfamily H 0.0024 0.0058 0.0058
Mycobacterium ulcerans dehydrogenase 0.0109 0.0678 0.2308
Echinococcus granulosus transient receptor potential ion channel A 0.0092 0.0553 0.0553
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.1337 0.9671 1
Echinococcus multilocularis FAD linked sulfhydryl oxidase ALR 0.0034 0.0129 0.0129
Loa Loa (eye worm) hypothetical protein 0.018 0.1203 0.196
Leishmania major 3-keto-dihydrosphingosine reductase 0.0019 0.0025 0.0015
Trichomonas vaginalis chromobox protein, putative 0.0042 0.0193 0.0262
Loa Loa (eye worm) hypothetical protein 0.0054 0.0278 0.0453
Wolbachia endosymbiont of Brugia malayi Short-chain alcohol dehydrogenase family enzyme 0.0019 0.0025 0.0025
Loa Loa (eye worm) hypothetical protein 0.0098 0.0603 0.0982
Echinococcus multilocularis potassium voltage gated channel subfamily H 0.0024 0.0058 0.0058
Trichomonas vaginalis glucosylceramidase, putative 0.0173 0.1146 0.1623
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0038 0.0163 0.0265
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0118 0.0747 0.0747
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.0018 0.0018 0.0029
Loa Loa (eye worm) hypothetical protein 0.0054 0.0278 0.0453
Echinococcus multilocularis nuclear factor of activated T cells 5 0.0143 0.0932 0.0932
Trichomonas vaginalis ap endonuclease, putative 0.0018 0.0018 0.0011
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.0018 0.0018 0.0018
Trypanosoma brucei beta-D-hydroxybutyrate dehydrogenase 0.0019 0.0025 0.0007
Echinococcus granulosus TRP transient receptor potential channel 0.0048 0.0233 0.0233
Leishmania major 2,4-dienoyl-coa reductase-like protein 0.0109 0.0678 0.0691
Mycobacterium tuberculosis Probable short chain alcohol dehydrogenase/reductase 0.0019 0.0025 0.0014
Mycobacterium ulcerans NADPH:adrenodoxin oxidoreductase FprA 0.0109 0.0678 0.2308
Schistosoma mansoni opsin-like receptor 0.0054 0.0278 0.0274
Echinococcus granulosus carbonyl reductase 1 0.0019 0.0025 0.0025
Loa Loa (eye worm) hypothetical protein 0.0074 0.0424 0.0691
Echinococcus granulosus inositol monophosphatase 1 0.0147 0.0959 0.0959
Echinococcus granulosus Aryl hydrocarbon receptor nuclear 0.0025 0.0067 0.0067
Echinococcus granulosus mitogen activated protein kinase 0.0102 0.063 0.063
Schistosoma mansoni short chain dehydrogenase 0.0019 0.0025 0.0021
Brugia malayi RNA binding protein 0.0062 0.0338 0.055
Echinococcus multilocularis calcium activated potassium channel 0.0017 0.0005 0.0005
Loa Loa (eye worm) hypothetical protein 0.0083 0.049 0.0798
Echinococcus multilocularis BC026374 protein (S09 family) 0.0083 0.049 0.049
Toxoplasma gondii pyridine nucleotide-disulfide oxidoreductase domain-containing protein 0.0109 0.0678 0.1623
Brugia malayi hypothetical protein 0.0083 0.049 0.0798
Plasmodium falciparum steroid dehydrogenase, putative 0.0019 0.0025 0.0036
Entamoeba histolytica glutamate synthase beta subunit, putative 0.0109 0.0678 0.1603
Loa Loa (eye worm) aryl Hydrocarbon receptor Associated protein family member 0.0025 0.0067 0.0109
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0034 0.013 0.0171
Echinococcus granulosus serine protein kinase ATM 0.0038 0.0163 0.0163
Entamoeba histolytica oxidoreductase, short chain dehydrogenase/reductase family 0.0019 0.0025 0.0036
Schistosoma mansoni sodium/chloride dependent transporter 0.0025 0.0064 0.0061
Echinococcus granulosus ubiquitin specific protease 41 0.0038 0.0164 0.0164
Chlamydia trachomatis fructose-6-phosphate phosphotransferase 0.003 0.01 0.0126
Schistosoma mansoni cyclic-nucleotide-gated cation channel 0.0021 0.0033 0.0029
Loa Loa (eye worm) hypothetical protein 0.0054 0.0278 0.0453
Plasmodium vivax SET domain protein, putative 0.0123 0.078 0.1872
Brugia malayi hypoxia-induced factor 1 0.0299 0.2075 0.3379
Trypanosoma cruzi hypothetical protein, conserved 0.0019 0.0025 0.0015
Leishmania major short chain dehydrogenase-like protein 0.0019 0.0025 0.0015
Echinococcus multilocularis fmrfamide receptor 0.0054 0.0278 0.0278
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.0018 0.0018 0.0018
Echinococcus granulosus uncharacterized sodium dependent transporter 0.0025 0.0064 0.0064
Brugia malayi ERG2 and Sigma1 receptor like protein 0.0356 0.2487 0.405
Echinococcus multilocularis potassium:sodium hyperpolarization activated 0.0021 0.0033 0.0033
Loa Loa (eye worm) hypothetical protein 0.0325 0.2259 0.3679
Echinococcus multilocularis short transient receptor potential channel 6 0.0075 0.0435 0.0435
Trypanosoma cruzi short chain dehydrogenase/reductase, putative 0.0019 0.0025 0.0015
Echinococcus multilocularis 3 ketodihydrosphingosine reductase 0.0019 0.0025 0.0025
Brugia malayi Protein kinase domain containing protein 0.0029 0.0095 0.0154
Trichomonas vaginalis conserved hypothetical protein 0.0038 0.0164 0.022
Trichomonas vaginalis PIKK family atypical protein kinase 0.0038 0.0163 0.0218
Trypanosoma cruzi PAS-domain containing phosphoglycerate kinase, putative 0.0025 0.0067 0.0059
Onchocerca volvulus 0.0019 0.0025 0.0021
Brugia malayi hypothetical protein 0.0025 0.0064 0.0105
Leishmania major target of rapamycin (TOR) kinase 2, putative 0.0065 0.0361 0.0363
Schistosoma mansoni peptide (allatostatin)-like receptor 0.0054 0.0278 0.0274
Schistosoma mansoni protein phosphatase 2C 0.0025 0.007 0.0066
Echinococcus multilocularis neuropeptide FF receptor 2 0.0054 0.0278 0.0278
Onchocerca volvulus 0.0019 0.0025 0.0021
Trypanosoma cruzi hypothetical protein, conserved 0.0019 0.0025 0.0015
Brugia malayi Dopamine receptor protein 2 0.0054 0.0278 0.0453
Loa Loa (eye worm) hypothetical protein 0.0039 0.0171 0.0279
Schistosoma mansoni microtubule-associated protein tau 0.1382 1 1
Plasmodium vivax dihydrolipoyl dehydrogenase, apicoplast, putative 0.0409 0.2878 0.6972
Loa Loa (eye worm) hypothetical protein 0.0054 0.0278 0.0453
Leishmania major dehydrogenase-like protein 0.0019 0.0025 0.0015
Loa Loa (eye worm) oxidoreductase 0.0019 0.0025 0.0041
Mycobacterium tuberculosis Probable cytochrome P450 132 Cyp132 0.0054 0.0279 0.0516
Schistosoma mansoni 6-phosphofructokinase 0.011 0.0685 0.0682
Loa Loa (eye worm) CYP4Cod1 0.0081 0.0476 0.0775
Trypanosoma cruzi PAB1-binding protein , putative 0.0074 0.0424 0.0428
Echinococcus granulosus tachykinin peptides receptor 99D 0.0054 0.0278 0.0278
Mycobacterium ulcerans short-chain membrane-associated dehydrogenase 0.0019 0.0025 0.0025
Schistosoma mansoni steroid dehydrogenase 0.0019 0.0025 0.0021
Schistosoma mansoni hypothetical protein 0.003 0.0102 0.0098
Leishmania major aldehyde dehydrogenase, mitochondrial precursor 0.0122 0.0774 0.079
Schistosoma mansoni alpha-1 adrenergic receptor 0.0054 0.0278 0.0274
Leishmania major 2,4-dienoyl-coa reductase fadh1, putative 0.0109 0.0678 0.0691
Mycobacterium tuberculosis Probable dehydrogenase/reductase 0.0019 0.0025 0.0014
Loa Loa (eye worm) hypothetical protein 0.0054 0.0278 0.0453
Brugia malayi hypothetical protein 0.0196 0.1316 0.2144
Schistosoma mansoni loxhd1 0.016 0.1055 0.1051
Leishmania major hypothetical protein, conserved 0.0109 0.0678 0.0691
Onchocerca volvulus 0.0054 0.0278 0.0383
Schistosoma mansoni short chain dehydrogenase 0.0019 0.0025 0.0021
Leishmania major calcium channel protein, putative,ion transporter, putative 0.0117 0.0743 0.0758
Schistosoma mansoni short chain dehydrogenase 0.0019 0.0025 0.0021
Schistosoma mansoni short chain dehydrogenase 0.0019 0.0025 0.0021
Trypanosoma cruzi cytochrome P450, putative 0.0081 0.0476 0.0482
Mycobacterium ulcerans cytochrome P450 187A4 Cyp187A4 0.0054 0.0279 0.0913
Schistosoma mansoni transcription factor LCR-F1 0.0035 0.0141 0.0137
Schistosoma mansoni hypothetical protein 0.0097 0.059 0.0586
Trichomonas vaginalis disulfide oxidoreductase, putative 0.0109 0.0678 0.0955
Echinococcus granulosus dihydropyrimidine dehydrogenase NADP 0.0109 0.0678 0.0678
Schistosoma mansoni glutamate synthase 0.0109 0.0678 0.0674
Leishmania major short chain dehydrogenase, putative 0.0019 0.0025 0.0015
Loa Loa (eye worm) hypothetical protein 0.0019 0.0025 0.0041
Schistosoma mansoni tar DNA-binding protein 0.0062 0.0338 0.0334
Mycobacterium ulcerans short chain dehydrogenase 0.0019 0.0025 0.0025
Mycobacterium tuberculosis Probable cytochrome P450 141 Cyp141 0.0054 0.0279 0.0516
Schistosoma mansoni neuropeptide receptor 0.0054 0.0278 0.0274
Loa Loa (eye worm) ctsf protein 0.0017 0.001 0.0017
Schistosoma mansoni biogenic amine (5HT) receptor 0.0172 0.1139 0.1136
Schistosoma mansoni voltage-gated potassium channel 0.0019 0.0023 0.0019
Echinococcus multilocularis transcription factor Dp 1 0.0039 0.0169 0.0169
Mycobacterium tuberculosis Possible cytochrome P450 135A1 Cyp135A1 0.0054 0.0279 0.0516
Echinococcus multilocularis phosphatidylinositol 3 and 4 kinase 0.0036 0.0149 0.0149
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0123 0.078 0.078
Echinococcus granulosus tyrosyl DNA phosphodiesterase 1 0.0068 0.0377 0.0377
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0123 0.078 0.0777
Echinococcus granulosus neuropeptides capa receptor 0.0054 0.0278 0.0278
Schistosoma mansoni neuropeptide receptor 0.0054 0.0278 0.0274
Mycobacterium ulcerans short chain dehydrogenase 0.0019 0.0025 0.0025
Toxoplasma gondii cytochrome p450 superfamily protein 0.0054 0.0279 0.0654
Echinococcus granulosus Ankyrin 0.0028 0.009 0.009
Echinococcus multilocularis acetylcholinesterase 0.0491 0.3476 0.3476
Entamoeba histolytica disulphide oxidoreductase, putative 0.0109 0.0678 0.1603
Onchocerca volvulus 0.016 0.1055 0.1493
Trichomonas vaginalis glucosylceramidase, putative 0.0164 0.1081 0.1531
Toxoplasma gondii inositol(myo)-1(or 4)-monophosphatase 2, putative 0.0147 0.0959 0.2307
Trichomonas vaginalis PIKK family atypical protein kinase 0.0045 0.0214 0.0292
Leishmania major protein kinase, putative 0.0031 0.0109 0.0102
Schistosoma mansoni neuroligin 3 (S09 family) 0.0083 0.049 0.0486
Loa Loa (eye worm) hypothetical protein 0.0083 0.049 0.0798
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.1337 0.9671 1
Trypanosoma cruzi cysteine peptidase, putative 0.0066 0.0368 0.037
Echinococcus multilocularis neuropeptide receptor 0.0054 0.0278 0.0278
Leishmania major PAS-domain containing phosphoglycerate kinase, putative 0.0025 0.0067 0.0059
Trichomonas vaginalis carboxylesterase domain containing protein, putative 0.0083 0.049 0.0686
Trichomonas vaginalis PIKK family atypical protein kinase 0.0065 0.0361 0.0501
Onchocerca volvulus 0.0052 0.0267 0.0367
Brugia malayi Immunoglobulin I-set domain containing protein 0.0028 0.0088 0.0143
Mycobacterium ulcerans cytochrome P450 123A3 Cyp123A3 0.0054 0.0279 0.0913
Echinococcus multilocularis serotonin receptor 0.0172 0.1139 0.1139
Mycobacterium ulcerans short-chain dehydrogenase 0.0019 0.0025 0.0025
Trichomonas vaginalis phosphofructokinase, putative 0.003 0.01 0.0128
Loa Loa (eye worm) Sodium:neurotransmitter symporter family protein 0.0025 0.0064 0.0105
Mycobacterium ulcerans hypothetical protein 0.0109 0.0678 0.2308
Trichomonas vaginalis phosphofructokinase, putative 0.003 0.01 0.0128
Echinococcus multilocularis orexin receptor type 2 0.0054 0.0278 0.0278
Mycobacterium tuberculosis Probable aldehyde dehydrogenase 0.0122 0.0774 0.1492
Brugia malayi Serotonin/octopamine receptor family protein 7 0.0054 0.0278 0.0453
Brugia malayi 6-phosphofructokinase 0.011 0.0685 0.1116
Trypanosoma brucei tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0068 0.0377 0.0372
Entamoeba histolytica protein kinase rad3, putative 0.0021 0.0033 0.0055
Entamoeba histolytica hypothetical protein 0.0035 0.0141 0.0314
Brugia malayi MAP kinase sur-1 0.0102 0.063 0.1026
Schistosoma mansoni sodium-dependent neurotransmitter transporter 0.0025 0.0064 0.0061
Loa Loa (eye worm) hypothetical protein 0.0054 0.0278 0.0453
Trichomonas vaginalis disulfide oxidoreductase, putative 0.0109 0.0678 0.0955
Echinococcus multilocularis serine:threonine protein kinase SMG1 0.0021 0.0033 0.0033
Echinococcus multilocularis carbonyl reductase 1 0.0019 0.0025 0.0025
Toxoplasma gondii histone lysine demethylase JMJD6a 0.0025 0.007 0.0144
Trypanosoma cruzi phosphatidylinositol kinase related protein, putative 0.0038 0.0163 0.0158
Loa Loa (eye worm) hypothetical protein 0.0019 0.0025 0.0041
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.018 0.1199 0.413
Mycobacterium leprae Conserved hypothetical protein 0.0054 0.0279 0.0502
Plasmodium falciparum ferrodoxin reductase-like protein 0.0109 0.0678 0.1623
Schistosoma mansoni voltage-gated potassium channel 0.0024 0.0058 0.0054
Mycobacterium tuberculosis Probable membrane NADH dehydrogenase NdhA 0.041 0.2884 0.5658
Schistosoma mansoni histamine-responsive GPCR (AAF21638) 0.0054 0.0278 0.0274
Onchocerca volvulus 0.0019 0.0025 0.0021
Schistosoma mansoni carbonyl reductase 0.0019 0.0025 0.0021
Brugia malayi hypothetical protein 0.0019 0.0025 0.0041
Echinococcus multilocularis short transient receptor potential channel 6 0.0075 0.0434 0.0434
Schistosoma mansoni jumonji/arid domain-containing protein 0.0096 0.0583 0.0579
Trypanosoma cruzi Lanosterol 14-alpha demethylase 0.0201 0.1355 0.1392
Mycobacterium ulcerans oxidoreductase 0.0019 0.0025 0.0025
Echinococcus granulosus tar DNA binding protein 0.0062 0.0338 0.0338
Loa Loa (eye worm) oxidoreductase 0.0019 0.0025 0.0041
Echinococcus granulosus voltage gated sodium channel Nav1 alpha subunit 0.0117 0.0743 0.0743
Schistosoma mansoni voltage-gated potassium channel 0.0053 0.027 0.0266
Trypanosoma cruzi cysteine peptidase, clan CA, family C1, cathepsin L-like, putative 0.0061 0.0326 0.0327
Loa Loa (eye worm) RecQ helicase 0.0021 0.0036 0.0059
Echinococcus multilocularis retinol dehydrogenase 11 0.0019 0.0025 0.0025
Mycobacterium tuberculosis Probable short-chain type dehydrogenase/reductase 0.0019 0.0025 0.0014
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0066 0.0368 0.0363
Schistosoma mansoni biogenic amine receptor 0.0054 0.0278 0.0274
Trichomonas vaginalis PIKK family atypical protein kinase 0.0054 0.0279 0.0384
Brugia malayi Serotonin receptor 0.0498 0.3531 0.5751
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0123 0.078 0.0777
Echinococcus granulosus cyclic nucleotide gated cation channel 0.0021 0.0033 0.0033
Trichomonas vaginalis PIKK family atypical protein kinase 0.0045 0.0214 0.0292
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.0018 0.0018 0.0008
Schistosoma mansoni steroid dehydrogenase 0.0019 0.0025 0.0021
Toxoplasma gondii oxidoreductase, putative 0.0019 0.0025 0.0036
Schistosoma mansoni gliotactin 0.0083 0.049 0.0486
Leishmania major short chain dehydrogenase, putative 0.0019 0.0025 0.0015
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0019 0.0025 0.0025
Echinococcus granulosus orexin receptor type 2 0.0054 0.0278 0.0278
Echinococcus granulosus biogenic amine 5HT receptor 0.0172 0.1139 0.1139
Brugia malayi jmjC domain containing protein 0.0025 0.007 0.0113
Mycobacterium ulcerans ketoacyl reductase 0.0019 0.0025 0.0025
Onchocerca volvulus 0.0973 0.7006 1
Plasmodium vivax thioredoxin reductase, putative 0.0579 0.4123 1
Plasmodium falciparum glutathione reductase 0.0579 0.4123 1
Mycobacterium tuberculosis Possible cytochrome P450 135B1 Cyp135B1 0.0054 0.0279 0.0516
Loa Loa (eye worm) cytochrome P450 family protein 0.0081 0.0476 0.0775
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0146 0.0952 0.155
Echinococcus multilocularis G protein coupled 5 hydroxytryptamine receptor 0.0054 0.0278 0.0278
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0019 0.0025 0.0041
Mycobacterium tuberculosis Possible ketoacyl reductase 0.0019 0.0025 0.0014
Brugia malayi GnHR receptor homolog 0.0054 0.0278 0.0453
Trichomonas vaginalis glucosylceramidase, putative 0.0249 0.1709 0.2429
Entamoeba histolytica hypothetical protein 0.0035 0.0141 0.0314
Trypanosoma cruzi STE group serine/threonine-protein kinase, putative 0.0026 0.0074 0.0066
Echinococcus multilocularis sodium dependent neurotransmitter transporter 0.0025 0.0064 0.0064
Mycobacterium ulcerans glutamate synthase subunit beta 0.0109 0.0678 0.2308
Giardia lamblia Hypothetical protein 0.0019 0.0025 0.0017
Brugia malayi Death domain containing protein 0.0028 0.0088 0.0143
Mycobacterium tuberculosis Possible short-chain dehydrogenase EphD 0.0019 0.0025 0.0014
Leishmania major ATP-dependent phosphofructokinase 0.011 0.0685 0.0699
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.018 0.1199 0.413
Mycobacterium ulcerans cytochrome P450 144A4 Cyp144A4 0.0054 0.0279 0.0913
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.1337 0.9671 1
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0019 0.0025 0.0041
Schistosoma mansoni short chain dehydrogenase 0.0019 0.0025 0.0021
Onchocerca volvulus 0.0054 0.0278 0.0383
Echinococcus granulosus neuropeptide receptor A26 0.0054 0.0278 0.0278
Loa Loa (eye worm) hypothetical protein 0.0054 0.0278 0.0453
Mycobacterium ulcerans short-chain dehydrogenase 0.0019 0.0025 0.0025
Schistosoma mansoni hypothetical protein 0.0054 0.0278 0.0274
Schistosoma mansoni retinoblastoma-binding protein 4 (rbbp4) 0.0028 0.009 0.0086
Mycobacterium ulcerans short chain dehydrogenase 0.0019 0.0025 0.0025
Mycobacterium ulcerans carboxylesterase, LipT 0.0083 0.049 0.1651
Loa Loa (eye worm) RNA binding protein 0.0062 0.0338 0.055
Trichomonas vaginalis apoptosis inducing factor, putative 0.0109 0.0678 0.0955
Echinococcus granulosus para nitrobenzyl esterase 0.0083 0.049 0.049
Trichomonas vaginalis PIKK family atypical protein kinase 0.0045 0.0214 0.0292
Echinococcus granulosus cytoplasmic intermediate filament protein 0.0025 0.0068 0.0068
Brugia malayi Pyridine nucleotide-disulphide oxidoreductase family protein 0.0109 0.0678 0.1104
Entamoeba histolytica myo-inositol monophosphatase, putative 0.0147 0.0959 0.2278
Echinococcus granulosus BC026374 protein S09 family 0.0083 0.049 0.049
Onchocerca volvulus 0.0031 0.0109 0.0141
Trichomonas vaginalis CMGC family protein kinase 0.0102 0.063 0.0886
Brugia malayi dehydrogenases, short chain protein 9 0.0019 0.0025 0.0041
Trichomonas vaginalis CMGC family protein kinase 0.0102 0.063 0.0886
Echinococcus granulosus Basic leucine zipper bZIP transcription factor 0.0249 0.1708 0.1708
Schistosoma mansoni tar DNA-binding protein 0.0062 0.0338 0.0334
Trichomonas vaginalis short-chain dehydrogenase, putative 0.0019 0.0025 0.0021
Schistosoma mansoni aldehyde dehydrogenase 0.0122 0.0774 0.077
Loa Loa (eye worm) unidentified vitellogenin-linked transcript protein 6 0.0054 0.0278 0.0453
Loa Loa (eye worm) hypothetical protein 0.0054 0.0278 0.0453
Brugia malayi 6-phosphofructokinase 0.011 0.0686 0.1117
Leishmania major cathepsin L-like protease 0.0066 0.0368 0.037
Trichomonas vaginalis phosphofructokinase, putative 0.003 0.01 0.0128
Mycobacterium tuberculosis Carboxylesterase LipT 0.0083 0.049 0.0932
Entamoeba histolytica glutamate synthase beta subunit, putative 0.0109 0.0678 0.1603
Brugia malayi intermediate filament protein 0.0052 0.0267 0.0435
Schistosoma mansoni hypothetical protein 0.0031 0.0111 0.0107
Trichomonas vaginalis hydroxyacyl dehydrogenase, putative 0.0019 0.0025 0.0021
Leishmania major 2-oxoglutarate dehydrogenase, e3 component, lipoamidedehydrogenase-like protein 0.1133 0.8176 0.8453
Loa Loa (eye worm) 3-hydroxyacyl-CoA dehydrogenase type II 0.016 0.1057 0.1721
Toxoplasma gondii oxidoreductase, short chain dehydrogenase/reductase family protein 0.0019 0.0025 0.0036
Echinococcus granulosus jumonji domain containing 1A 0.0025 0.007 0.007
Echinococcus multilocularis g-protein coupled receptor 0.0054 0.0278 0.0278
Schistosoma mansoni sodium-dependent neurotransmitter transporter 0.0025 0.0064 0.0061
Echinococcus multilocularis aryl hydrocarbon receptor 0.0025 0.0067 0.0067
Trypanosoma cruzi phosphatidylinositol 3-kinase, putative 0.0021 0.0033 0.0024
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 8 0.0038 0.0164 0.0164
Loa Loa (eye worm) hypothetical protein 0.0021 0.0033 0.0054
Loa Loa (eye worm) hypothetical protein 0.0054 0.0278 0.0453
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.0586 0.4175 1
Toxoplasma gondii sterol carrier protein-2 HAD-2SCP-2 0.0019 0.0025 0.0036
Mycobacterium ulcerans 6-phosphofructokinase 0.011 0.0685 0.2334
Plasmodium vivax FAD-linked sulfhydryl oxidase ERV1, putative 0.0034 0.0129 0.0289
Mycobacterium ulcerans short chain dehydrogenase 0.0019 0.0025 0.0025
Schistosoma mansoni short-chain dehydrogenase/reductase 0.0019 0.0025 0.0021
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0997 0.7176 0.7418
Echinococcus multilocularis rhodopsin orphan GPCR 0.0054 0.0278 0.0278
Echinococcus multilocularis cysteine protease 0.0017 0.001 0.001
Plasmodium falciparum AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0018 0.0018 0.0019
Loa Loa (eye worm) carboxylesterase 0.0083 0.049 0.0798
Leishmania major lanosterol 14-alpha-demethylase, putative 0.0201 0.1355 0.1392
Brugia malayi TAR-binding protein 0.0062 0.0338 0.055
Onchocerca volvulus 0.0054 0.0278 0.0383
Echinococcus granulosus neuroligin 0.0083 0.049 0.049
Echinococcus multilocularis cytoplasmic intermediate filament protein 0.0025 0.0068 0.0068
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0409 0.2878 0.2968
Schistosoma mansoni aldehyde dehydrogenase 0.0122 0.0774 0.077
Trypanosoma cruzi STE/STE11 serine/threonine-protein kinase, putative 0.0026 0.0074 0.0066
Leishmania major acetoin dehydrogenase e3 component-like protein 0.0997 0.7176 0.7418
Trichomonas vaginalis PIKK family atypical protein kinase 0.0041 0.0179 0.0242
Trypanosoma brucei JmjC domain, hydroxylase, putative 0.0025 0.007 0.0053
Loa Loa (eye worm) hypothetical protein 0.0107 0.0668 0.1089
Trichomonas vaginalis phosphofructokinase, putative 0.011 0.0685 0.0965
Echinococcus granulosus oxidoreductase 0.0019 0.0025 0.0025
Trypanosoma cruzi 2,4-dienoyl-coa reductase fadh1, putative 0.0109 0.0678 0.0691
Echinococcus granulosus sodium and chloride dependent glycine 0.0025 0.0064 0.0064
Loa Loa (eye worm) hypothetical protein 0.0054 0.0278 0.0453
Mycobacterium ulcerans short chain dehydrogenase 0.0019 0.0025 0.0025
Brugia malayi Cytochrome P450 family protein 0.0081 0.0476 0.0775
Schistosoma mansoni phd/f-box containing protein 0.0025 0.007 0.0066
Echinococcus multilocularis steroid dehydrogenase 0.0019 0.0025 0.0025
Echinococcus granulosus bloom syndrome protein 0.0021 0.0036 0.0036
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.005 0.0249 0.0249
Echinococcus multilocularis GPCR, family 2 0.0031 0.0111 0.0111
Echinococcus granulosus peregrin 0.003 0.0102 0.0102
Brugia malayi jmjC domain containing protein 0.0025 0.007 0.0113
Wolbachia endosymbiont of Brugia malayi dihydrolipoamide dehydrogenase E3 component 0.0409 0.2878 1
Schistosoma mansoni neuropeptide f receptor 76f 0.0054 0.0278 0.0274
Echinococcus multilocularis carbonyl reductase 1 0.0019 0.0025 0.0025
Loa Loa (eye worm) hypothetical protein 0.0017 0.0005 0.0008
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.0052 0.0267 0.0435
Loa Loa (eye worm) pyridine nucleotide-disufhide oxidoreductase 0.0109 0.0678 0.1104
Trichomonas vaginalis conserved hypothetical protein 0.0025 0.0067 0.0081
Schistosoma mansoni hypothetical protein 0.0031 0.0111 0.0107
Mycobacterium ulcerans cytochrome P450 105Q4 Cyp105Q4 0.0054 0.0279 0.0913
Trichomonas vaginalis glutamate synthase, putative 0.0109 0.0678 0.0955
Trypanosoma brucei mitogen activated protein kinase 4, putative 0.0102 0.063 0.0634
Schistosoma mansoni sodium/chloride dependent neurotransmitter transporter 0.0025 0.0064 0.0061
Mycobacterium ulcerans cytochrome P450 136A2 Cyp136A2 0.0054 0.0279 0.0913
Trichomonas vaginalis PIKK family atypical protein kinase 0.0021 0.0033 0.0033
Schistosoma mansoni hypothetical protein 0.0203 0.1366 0.1363
Entamoeba histolytica tyrosyl-DNA phosphodiesterase, putative 0.0068 0.0377 0.0881
Echinococcus multilocularis cysteine protease 0.0017 0.001 0.001
Trichomonas vaginalis glucosylceramidase, putative 0.0249 0.1709 0.2429
Trichomonas vaginalis PIKK family atypical protein kinase 0.0054 0.0279 0.0384
Plasmodium vivax hypothetical protein, conserved 0.0025 0.0064 0.0132
Brugia malayi sulfakinin receptor protein 0.0054 0.0278 0.0453
Schistosoma mansoni hypothetical protein 0.0031 0.0111 0.0107
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0586 0.4175 0.5955
Echinococcus multilocularis g protein coupled receptor 0.0054 0.0278 0.0278
Schistosoma mansoni sulfide quinone reductase 0.0109 0.0678 0.0674
Mycobacterium ulcerans short chain dehydrogenase 0.0019 0.0025 0.0025
Brugia malayi G protein-coupled receptor 0.0054 0.0278 0.0453
Plasmodium vivax type II NADH:ubiquinone oxidoreductase, putative 0.0109 0.0678 0.1623
Giardia lamblia NADH oxidase lateral transfer candidate 0.0409 0.2878 0.6879
Schistosoma mansoni chromobox protein 0.007 0.0397 0.0394
Loa Loa (eye worm) cytochrome P450 0.0054 0.0279 0.0455
Giardia lamblia Ubiquitin carboxyl-terminal hydrolase 4 0.0038 0.0164 0.0352
Mycobacterium tuberculosis Probable short-chain type oxidoreductase 0.0019 0.0025 0.0014
Trichomonas vaginalis phosphofructokinase, putative 0.011 0.0685 0.0965
Toxoplasma gondii phosphofructokinase domain-containing protein 0.003 0.01 0.0218
Loa Loa (eye worm) hypothetical protein 0.0123 0.078 0.1271
Trypanosoma cruzi NAD(P)-dependent oxidoreductase, putative 0.0019 0.0025 0.0015
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0035 0.0141 0.0141
Onchocerca volvulus 0.0072 0.0407 0.0567
Loa Loa (eye worm) hypothetical protein 0.0054 0.0278 0.0453
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0066 0.0368 0.0363
Echinococcus multilocularis acetylcholinesterase 0.0491 0.3476 0.3476
Toxoplasma gondii Erv1 / Alr family protein 0.0034 0.0129 0.0289
Loa Loa (eye worm) hypothetical protein 0.0243 0.1658 0.27
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0054 0.0278 0.0278
Leishmania major quinonoid dihydropteridine reductase 0.0019 0.0025 0.0015
Trichomonas vaginalis dihydroorotate dehydrogenase, putative 0.0109 0.0678 0.0955
Echinococcus granulosus thioredoxin glutathione reductase 0.058 0.4128 0.4128
Echinococcus multilocularis hyperpolarization activated cyclic 0.0021 0.0033 0.0033
Plasmodium falciparum ATP-dependent 6-phosphofructokinase 0.003 0.01 0.0218
Trypanosoma cruzi oxidoreductase-like protein, putative 0.0019 0.0025 0.0015
Trichomonas vaginalis PIKK family atypical protein kinase 0.0065 0.0361 0.0501
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0019 0.0025 0.0025
Entamoeba histolytica estradiol 17-beta-dehydrogenase, putative 0.0019 0.0025 0.0036
Onchocerca volvulus 0.016 0.1055 0.1493
Trichomonas vaginalis glucosylceramidase, putative 0.0249 0.1709 0.2429
Brugia malayi hypothetical protein 0.016 0.1055 0.1718
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0586 0.4175 0.5955
Toxoplasma gondii aldehyde dehydrogenase 0.0122 0.0774 0.1857
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0054 0.0278 0.0274
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0586 0.4175 0.5955
Echinococcus multilocularis jun protein 0.0249 0.1708 0.1708
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.005 0.0249 0.0245
Echinococcus multilocularis sodium and chloride dependent glycine 0.0025 0.0064 0.0064
Brugia malayi dehydrogenases, short chain protein 2 0.0019 0.0025 0.0041
Plasmodium falciparum thioredoxin reductase 0.0409 0.2878 0.6972
Brugia malayi follicle stimulating hormone receptor 0.0558 0.3964 0.6456
Entamoeba histolytica phosphofructokinase, putative 0.011 0.0685 0.1621
Echinococcus granulosus family S9 non peptidase ue S09 family 0.0083 0.049 0.049
Echinococcus granulosus somatostatin receptor 0.0054 0.0278 0.0278
Mycobacterium tuberculosis Probable cytochrome P450 144 Cyp144 0.0054 0.0279 0.0516
Brugia malayi Hypothetical oxidoreductase F56D1.5 0.0019 0.0025 0.0041
Loa Loa (eye worm) hypothetical protein 0.0048 0.0233 0.0379
Mycobacterium ulcerans cytochrome P450 124A1, Cyp124A1 0.0054 0.0279 0.0913
Mycobacterium tuberculosis Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras 0.0711 0.5084 1
Leishmania major quinonoid dihydropteridine reductase 0.0019 0.0025 0.0015
Wolbachia endosymbiont of Brugia malayi dihydrolipoamide dehydrogenase E3 component 0.0409 0.2878 1
Plasmodium falciparum ataxin-2 like protein, putative 0.0074 0.0424 0.1006
Echinococcus granulosus neuropeptide Y receptor 0.0054 0.0278 0.0278
Toxoplasma gondii pyridine nucleotide-disulfide oxidoreductase domain-containing protein 0.0109 0.0678 0.1623
Schistosoma mansoni family S9 non-peptidase homologue (S09 family) 0.0083 0.049 0.0486
Brugia malayi Cathepsin L-like precursor 0.0017 0.001 0.0017
Schistosoma mansoni jun-related protein 0.0203 0.1366 0.1363
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.1133 0.8176 0.8453
Brugia malayi chromobox protein homolog 3 0.0039 0.0171 0.0279
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0586 0.4175 0.5955
Brugia malayi Dopamine receptor 0.0054 0.0278 0.0453
Mycobacterium leprae PROBABLE NADH DEHYDROGENASE NDH 0.041 0.2884 0.5652
Leishmania major hypothetical protein, conserved 0.0019 0.0025 0.0015
Leishmania major trypanothione reductase 0.0579 0.4123 0.4257
Echinococcus multilocularis dihydropyrimidine dehydrogenase (NADP+) 0.0109 0.0678 0.0678
Schistosoma mansoni opsin-like receptor 0.0054 0.0278 0.0274
Trypanosoma cruzi hypothetical protein, conserved 0.0109 0.0678 0.0691
Echinococcus granulosus cyclic nucleotide gated cation channel 0.0021 0.0033 0.0033
Echinococcus multilocularis chromobox protein 1 0.007 0.0397 0.0397
Trypanosoma cruzi Lanosterol 14-alpha demethylase 0.0201 0.1355 0.1392
Mycobacterium tuberculosis Probable oxidoreductase 0.0019 0.0025 0.0014
Mycobacterium ulcerans short chain dehydrogenase 0.0019 0.0025 0.0025
Echinococcus granulosus thyrotropin releasing hormone receptor 0.0054 0.0278 0.0278
Loa Loa (eye worm) norepinephrine transporter 0.0146 0.0952 0.155
Schistosoma mansoni peptide (FMRFamide/neurokinin-3)-like receptor 0.0054 0.0278 0.0274
Brugia malayi Sodium:neurotransmitter symporter family protein 1, putative 0.0025 0.0064 0.0105
Echinococcus multilocularis neuropeptides capa receptor 0.0054 0.0278 0.0278
Echinococcus multilocularis chromobox protein 1 0.007 0.0397 0.0397
Echinococcus multilocularis serine protein kinase ATM 0.0038 0.0163 0.0163
Trichomonas vaginalis conserved hypothetical protein 0.0023 0.005 0.0057
Giardia lamblia Short-chain dehydrogenase, putative 0.0019 0.0025 0.0017
Leishmania major quinonoid dihydropteridine reductase 0.0019 0.0025 0.0015
Onchocerca volvulus 0.0019 0.0025 0.0021
Toxoplasma gondii thioredoxin reductase 0.0579 0.4123 1
Loa Loa (eye worm) oxidoreductase 0.0019 0.0025 0.0041
Schistosoma mansoni biogenic amine receptor 0.0054 0.0278 0.0274
Loa Loa (eye worm) hypothetical protein 0.0054 0.0278 0.0453
Onchocerca volvulus Heterochromatin protein 1 homolog 0.0039 0.0171 0.023
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0054 0.0278 0.0274
Plasmodium falciparum dihydrolipoyl dehydrogenase, mitochondrial 0.0409 0.2878 0.6972
Trypanosoma brucei short-chain dehydrogenase, putative 0.0019 0.0025 0.0007
Echinococcus multilocularis transfer RNA-Lys 0.0072 0.0407 0.0407
Echinococcus granulosus rhodopsin orphan GPCR 0.0054 0.0278 0.0278
Mycobacterium ulcerans short chain dehydrogenase 0.0019 0.0025 0.0025
Loa Loa (eye worm) neuropeptide F receptor 0.0054 0.0278 0.0453
Mycobacterium ulcerans short chain dehydrogenase 0.0019 0.0025 0.0025
Loa Loa (eye worm) cyclic-nucleotide gated cation channel 0.0021 0.0033 0.0054
Echinococcus granulosus Transcription factor JmjC domain containing protein 0.0157 0.1035 0.1035
Echinococcus granulosus pyroglutamylated rfamide peptide receptor 0.0054 0.0278 0.0278
Mycobacterium tuberculosis Probable cytochrome P450 143 Cyp143 0.0054 0.0279 0.0516
Schistosoma mansoni hypothetical protein 0.0035 0.0141 0.0137
Loa Loa (eye worm) hypoxia-induced factor 1 0.0299 0.2075 0.3379
Chlamydia trachomatis two component regulatory system sensor histidine kinase 0.0025 0.0067 0.0009
Trypanosoma cruzi trypanothione reductase, putative 0.0579 0.4123 0.4257
Trypanosoma cruzi cytochrome p450-like protein, putative 0.0054 0.0279 0.0278
Schistosoma mansoni cytochrome P450 0.0054 0.0279 0.0275
Schistosoma mansoni short chain dehydrogenase 0.0019 0.0025 0.0021
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0019 0.0025 0.0041
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0066 0.0368 0.0363
Mycobacterium tuberculosis Probable cytochrome P450 138 Cyp138 0.0054 0.0279 0.0516
Trichomonas vaginalis guanylate cyclase, putative 0.0025 0.0067 0.0081
Mycobacterium leprae possible inositol monophosphatase SubH (IMPase) (inositol-1-phosphatase) (I-1-Pase ). 0.0132 0.0846 0.1623
Loa Loa (eye worm) hypothetical protein 0.0019 0.0025 0.0041
Schistosoma mansoni serine/threonine protein kinase 0.0102 0.063 0.0626
Mycobacterium tuberculosis Probable cytochrome P450 136 Cyp136 0.0054 0.0279 0.0516
Loa Loa (eye worm) PHD-finger family protein 0.003 0.0102 0.0167
Mycobacterium tuberculosis Probable oxidoreductase 0.0019 0.0025 0.0014
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0054 0.0278 0.0274
Schistosoma mansoni ap endonuclease 0.0018 0.0018 0.0014
Echinococcus multilocularis rhodopsin orphan GPCR 0.0054 0.0278 0.0278
Trypanosoma cruzi NAD(P)-dependent oxidoreductase, putative 0.0019 0.0025 0.0015
Leishmania major hypothetical protein, conserved 0.0025 0.007 0.0061
Loa Loa (eye worm) carboxylesterase 0.0083 0.049 0.0798
Loa Loa (eye worm) hypothetical protein 0.0024 0.0061 0.01
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0098 0.0603 0.0982
Schistosoma mansoni amine GPCR 0.0054 0.0278 0.0274
Loa Loa (eye worm) phosphatidylinositol 3 0.0065 0.0361 0.0587
Brugia malayi Dopamine receptor protein 1 0.0054 0.0278 0.0453
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0031 0.0111 0.018
Loa Loa (eye worm) hypothetical protein 0.0031 0.0111 0.018
Onchocerca volvulus Heterochromatin protein 1 homolog 0.0042 0.0193 0.0261
Mycobacterium tuberculosis Probable fructose-bisphosphate aldolase Fba 0.0286 0.198 0.3872
Trypanosoma cruzi short-chain dehydrogenase, putative 0.0019 0.0025 0.0015
Trypanosoma cruzi PAS-domain containing phosphoglycerate kinase, putative 0.0025 0.0067 0.0059
Echinococcus granulosus JmjC domain containing protein 4 0.0025 0.007 0.007
Echinococcus multilocularis cathepsin l cysteine peptidase 0.0017 0.001 0.001
Echinococcus multilocularis g protein coupled receptor 0.0054 0.0278 0.0278
Loa Loa (eye worm) 6-phosphofructokinase 0.011 0.0685 0.1116
Loa Loa (eye worm) hypothetical protein 0.0052 0.0267 0.0435
Echinococcus multilocularis Dehydrogenase:reductase SDR family 0.0019 0.0025 0.0025
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0019 0.0025 0.0025
Trichomonas vaginalis conserved hypothetical protein 0.0028 0.0087 0.011
Echinococcus granulosus neuropeptide s receptor 0.0054 0.0278 0.0278
Plasmodium vivax dihydrolipoyl dehydrogenase, mitochondrial, putative 0.0409 0.2878 0.6972
Trichomonas vaginalis conserved hypothetical protein 0.0025 0.0067 0.0081
Echinococcus granulosus G protein coupled receptor 139 0.0054 0.0278 0.0278
Onchocerca volvulus 0.0083 0.049 0.0686
Echinococcus multilocularis cathepsin L cysteine protease 0.0017 0.001 0.001
Mycobacterium tuberculosis Probable cytochrome P450 137 Cyp137 0.0054 0.0279 0.0516
Brugia malayi hypothetical protein 0.0054 0.0278 0.0453
Plasmodium falciparum thioredoxin reductase 0.0579 0.4123 1
Echinococcus multilocularis lysine specific demethylase 5A 0.0096 0.0583 0.0583
Mycobacterium ulcerans putative regulatory protein 0.0072 0.0407 0.1361
Brugia malayi dihydrolipoyl dehydrogenase, mitochondrial precursor, putative 0.0409 0.2878 0.4687
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0102 0.063 0.0642
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0019 0.0025 0.0041
Leishmania major phosphatidylinositol kinase related protein, putative 0.0025 0.0064 0.0055
Echinococcus granulosus histone lysine methyltransferase setb 0.0123 0.078 0.078
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0019 0.0025 0.0041
Echinococcus granulosus cyclic nucleotide gated cation channel alpha 3 0.0021 0.0033 0.0033
Brugia malayi ORL1-like opioid receptor 0.0054 0.0278 0.0453
Echinococcus multilocularis thyrotropin releasing hormone receptor 0.0054 0.0278 0.0278
Echinococcus granulosus aldehyde dehydrogenase mitochondrial 0.0122 0.0774 0.0774
Echinococcus multilocularis biogenic amine (5HT) receptor 0.0054 0.0278 0.0278
Echinococcus multilocularis musashi 0.0052 0.0267 0.0267
Trichomonas vaginalis glucosylceramidase, putative 0.0249 0.1709 0.2429
Loa Loa (eye worm) hypothetical protein 0.0054 0.0278 0.0453
Echinococcus multilocularis dihydropyrimidine dehydrogenase (NADP+) 0.0109 0.0678 0.0678
Echinococcus granulosus rhodopsin orphan GPCR 0.0054 0.0278 0.0278
Leishmania major mitogen activated protein kinase 4, putative;with=GeneDB:LmxM19.1440 0.0102 0.063 0.0642
Onchocerca volvulus 0.0054 0.0278 0.0383
Mycobacterium ulcerans short chain dehydrogenase 0.0019 0.0025 0.0025
Loa Loa (eye worm) follicle stimulating hormone receptor 0.0558 0.3964 0.6456
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.005 0.0249 0.0406
Loa Loa (eye worm) hypothetical protein 0.0038 0.0164 0.0267
Trichomonas vaginalis short-chain dehydrogenase, putative 0.0019 0.0025 0.0021
Wolbachia endosymbiont of Brugia malayi thioredoxin reductase 0.0109 0.0678 0.2308
Trichomonas vaginalis adenylate and guanylate cyclases, putative 0.0025 0.0067 0.0081
Trypanosoma cruzi Phosphatidylinositol 3-kinase tor1 0.0065 0.0361 0.0363
Plasmodium vivax steroid dehydrogenase, putative 0.0019 0.0025 0.0036
Loa Loa (eye worm) acetylcholinesterase 1 0.0491 0.3476 0.5661
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0019 0.0025 0.0041
Entamoeba histolytica hypothetical protein, conserved 0.0019 0.0025 0.0036
Trypanosoma cruzi STE group serine/threonine-protein kinase, putative 0.0026 0.0074 0.0066
Echinococcus granulosus epidermal retinal dehydrogenase 2 0.0019 0.0025 0.0025
Mycobacterium tuberculosis Cytochrome P450 51 Cyp51 (CYPL1) (P450-L1A1) (sterol 14-alpha demethylase) (lanosterol 14-alpha demethylase) (P450-14DM) 0.0201 0.1355 0.264
Schistosoma mansoni amine GPCR 0.0054 0.0278 0.0274
Trypanosoma cruzi major cysteine proteinase, putative 0.0052 0.0264 0.0263
Loa Loa (eye worm) hypothetical protein 0.0025 0.0064 0.0105
Trypanosoma brucei 2,4-dienoyl-coa reductase-like protein 0.0109 0.0678 0.0684
Entamoeba histolytica short chain dehydrogenase family protein 0.0019 0.0025 0.0036
Schistosoma mansoni glutamate synthase 0.0109 0.0678 0.0674
Trichomonas vaginalis PIKK family atypical protein kinase 0.0054 0.0279 0.0384
Schistosoma mansoni ankyrin 23/unc44 0.0028 0.0088 0.0084
Schistosoma mansoni netrin receptor unc5 0.0028 0.0088 0.0084
Mycobacterium tuberculosis Probable dehydrogenase/reductase 0.0019 0.0025 0.0014
Schistosoma mansoni ubiquitin-specific peptidase 2 (C19 family) 0.0038 0.0164 0.016
Loa Loa (eye worm) hypothetical protein 0.0083 0.049 0.0798
Entamoeba histolytica phosphofructokinase, putative 0.011 0.0685 0.1621
Mycobacterium tuberculosis Possible oxidoreductase 0.0019 0.0025 0.0014
Schistosoma mansoni ataxia telangiectasia mutated (atm)-related 0.0065 0.0361 0.0357
Mycobacterium ulcerans short chain dehydrogenase 0.0019 0.0025 0.0025
Echinococcus granulosus single minded 2 0.0075 0.0431 0.0431
Mycobacterium leprae Possible regulatory protein 0.0025 0.0067 0.0083
Brugia malayi hypothetical protein 0.0054 0.0278 0.0453
Trichomonas vaginalis PIKK family atypical protein kinase 0.0036 0.0149 0.0199
Echinococcus multilocularis G protein coupled receptor 139 0.0054 0.0278 0.0278
Echinococcus multilocularis lysine specific demethylase 6a 0.0025 0.007 0.007
Echinococcus granulosus survival motor neuron protein 1 0.0474 0.335 0.335
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0054 0.0278 0.0274
Plasmodium falciparum NAD(P)H-dependent glutamate synthase, putative 0.0109 0.0678 0.1623
Mycobacterium tuberculosis Probable thioredoxin reductase TrxB2 (TRXR) (TR) 0.0109 0.0678 0.1303
Brugia malayi hypothetical protein 0.0325 0.2259 0.3679
Trichomonas vaginalis PIKK family atypical protein kinase 0.0036 0.0149 0.0199
Trypanosoma cruzi hypothetical protein, conserved 0.0019 0.0025 0.0015
Loa Loa (eye worm) hypothetical protein 0.0017 0.001 0.0017
Schistosoma mansoni steroid dehydrogenase 0.0019 0.0025 0.0021
Echinococcus multilocularis lipoxygenase domain containing protein 0.016 0.1055 0.1055
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0054 0.0278 0.0274
Brugia malayi hypothetical protein 0.0019 0.0025 0.0041
Echinococcus granulosus g protein coupled receptor 0.0054 0.0278 0.0278
Mycobacterium ulcerans short-chain type oxidoreductase 0.0019 0.0025 0.0025
Giardia lamblia Fructose-bisphosphate aldolase 0.0586 0.4175 1
Brugia malayi Pre-SET motif family protein 0.0855 0.6139 1
Trypanosoma brucei short-chain dehydrogenase, putative 0.0019 0.0025 0.0007
Onchocerca volvulus 0.0054 0.0278 0.0383
Mycobacterium tuberculosis Probable dehydrogenase 0.041 0.2884 0.5658
Schistosoma mansoni myosin xvIII 0.0054 0.0278 0.0274
Trichomonas vaginalis PIKK family atypical protein kinase 0.0056 0.0296 0.0408
Echinococcus multilocularis rhodopsin orphan GPCR 0.0054 0.0278 0.0278
Schistosoma mansoni rab6-interacting 0.016 0.1055 0.1051
Trypanosoma cruzi apurinic/apyrimidinic endonuclease 0.0018 0.0018 0.0008
Echinococcus granulosus arachidonate 5 lipoxygenase 0.0707 0.5054 0.5054
Loa Loa (eye worm) hypothetical protein 0.0054 0.0278 0.0453
Trypanosoma brucei short-chain dehydrogenase, putative 0.0019 0.0025 0.0007
Brugia malayi Tyrosyl-DNA phosphodiesterase family protein 0.0068 0.0377 0.0614
Onchocerca volvulus 0.0019 0.0025 0.0021
Trichomonas vaginalis PIKK family atypical protein kinase 0.0045 0.0214 0.0291
Echinococcus granulosus transient receptor potential gamma protein 0.0107 0.0668 0.0668
Echinococcus granulosus rhodopsin orphan GPCR 0.0054 0.0278 0.0278
Loa Loa (eye worm) oxidoreductase 0.0019 0.0025 0.0041
Brugia malayi Dehydrogenases, short chain protein 2 0.0019 0.0025 0.0041
Schistosoma mansoni survival motor neuron protein 0.0097 0.059 0.0586
Loa Loa (eye worm) hypothetical protein 0.0024 0.0058 0.0094
Echinococcus granulosus neuropeptides capa receptor 0.0054 0.0278 0.0278
Trypanosoma brucei ATP-dependent 6-phosphofructokinase, glycosomal 0.011 0.0685 0.0692
Echinococcus multilocularis thioredoxin glutathione reductase 0.058 0.4128 0.4128
Trichomonas vaginalis short-chain dehydrogenase, putative 0.0019 0.0025 0.0021
Trypanosoma cruzi Present in the outer mitochondrial membrane proteome 4 0.0034 0.0129 0.0123
Brugia malayi Uncoordinated protein 44 0.0028 0.0088 0.0143
Echinococcus granulosus alpha 1A adrenergic receptor 0.0054 0.0278 0.0278
Onchocerca volvulus 0.0019 0.0025 0.0021
Trichomonas vaginalis glucosylceramidase, putative 0.0164 0.1081 0.1531
Loa Loa (eye worm) hypothetical protein 0.0172 0.1139 0.1855
Trichomonas vaginalis guanylate cyclase, putative 0.0025 0.0067 0.0081
Echinococcus multilocularis cyclic nucleotide gated cation channel 0.0021 0.0033 0.0033
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0854 0.6133 0.6133
Toxoplasma gondii oxidoreductase, short chain dehydrogenase/reductase family protein 0.0019 0.0025 0.0036
Echinococcus multilocularis alpha 1A adrenergic receptor 0.0054 0.0278 0.0278
Plasmodium vivax NAD(P)H-dependent glutamate synthase, putative 0.0109 0.0678 0.1623
Entamoeba histolytica thioredoxin reductase, putative 0.0109 0.0678 0.1603
Entamoeba histolytica pyridine nucleotide-disulfide oxidoreductase family protein 0.0109 0.0678 0.1603
Mycobacterium ulcerans cytochrome P450 143A3 Cyp143A3 0.0054 0.0279 0.0913
Giardia lamblia Reductase, putative 0.0019 0.0025 0.0017
Trypanosoma brucei phosphatidylinositol 3-related kinase, putative 0.0036 0.0149 0.0136
Entamoeba histolytica hypothetical protein 0.0019 0.0025 0.0036
Loa Loa (eye worm) hypothetical protein 0.0474 0.335 0.5456
Loa Loa (eye worm) hypothetical protein 0.0109 0.0678 0.1104
Echinococcus multilocularis neuropeptide Y receptor 0.0054 0.0278 0.0278
Trichomonas vaginalis PIKK family atypical protein kinase 0.0043 0.0197 0.0266
Echinococcus multilocularis peptide (allatostatin:somatostatin) 0.0054 0.0278 0.0278
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0855 0.6139 1
Trichomonas vaginalis CMGC family protein kinase 0.0102 0.063 0.0886
Mycobacterium ulcerans oxidoreductase 0.0019 0.0025 0.0025
Mycobacterium tuberculosis Probable dehydrogenase 0.0019 0.0025 0.0014
Echinococcus multilocularis cathepsin l cysteine peptidase 0.0017 0.001 0.001
Mycobacterium tuberculosis Probable short-chain type dehydrogenase/reductase 0.0019 0.0025 0.0014
Mycobacterium ulcerans short chain dehydrogenase 0.0019 0.0025 0.0025
Giardia lamblia Pyrophosphate-fructose 6-phosphate 1-phosphotransferase alpha subunit 0.003 0.01 0.0197
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0066 0.0368 0.0363
Echinococcus multilocularis rhodopsin orphan GPCR 0.0054 0.0278 0.0278
Plasmodium falciparum oxidoreductase, short-chain dehydrogenase family, putative 0.0019 0.0025 0.0036
Echinococcus multilocularis family S9 non peptidase ue (S09 family) 0.0083 0.049 0.049
Schistosoma mansoni cyclic-nucleotide-gated cation channel 0.0021 0.0033 0.0029
Trypanosoma brucei ubiquitin carboxyl-terminal hydrolase, putative 0.0038 0.0164 0.0151
Echinococcus multilocularis neuropeptide receptor 0.0054 0.0278 0.0278
Trichomonas vaginalis glutathione reductase, putative 0.0409 0.2878 0.41
Schistosoma mansoni short chain dehydrogenase 0.0019 0.0025 0.0021
Trichomonas vaginalis short-chain dehydrogenase, putative 0.0019 0.0025 0.0021
Mycobacterium tuberculosis Probable cytochrome P450 128 Cyp128 0.0054 0.0279 0.0516
Trypanosoma brucei phosphatidylinositol 4-kinase, putative 0.0065 0.0361 0.0355
Schistosoma mansoni steroid dehydrogenase 0.0019 0.0025 0.0021
Trypanosoma cruzi hypothetical protein, conserved 0.0019 0.0025 0.0015
Mycobacterium ulcerans short chain dehydrogenase 0.0019 0.0025 0.0025
Echinococcus granulosus short transient receptor potential channel 6 0.0075 0.0435 0.0435
Echinococcus multilocularis serotonin transporter 0.0146 0.0952 0.0952
Echinococcus granulosus serotonin transporter 0.0146 0.0952 0.0952
Trichomonas vaginalis steroid dehydrogenase, putative 0.0019 0.0025 0.0021
Plasmodium falciparum transporter, putative 0.0025 0.0064 0.0132
Brugia malayi Carboxylesterase family protein 0.0491 0.3476 0.5661
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0586 0.4175 0.5955
Trypanosoma brucei PAB1-binding protein , putative 0.0074 0.0424 0.0421
Trichomonas vaginalis short-chain dehydrogenases/reductase, putative 0.0019 0.0025 0.0021
Onchocerca volvulus 0.0054 0.0278 0.0383
Onchocerca volvulus 0.0083 0.049 0.0686
Brugia malayi putative neuropeptide receptor NPR1 0.0054 0.0278 0.0453
Mycobacterium tuberculosis POSSIBLE PARA-NITROBENZYL ESTERASE (FRAGMENT) 0.0083 0.049 0.0932
Treponema pallidum sodium- and chloride- dependent transporter 0.0146 0.0952 0.2246
Brugia malayi Cytochrome P450 family protein 0.0054 0.0279 0.0455
Onchocerca volvulus 0.0054 0.0278 0.0383
Loa Loa (eye worm) hypothetical protein 0.016 0.1055 0.1718
Echinococcus granulosus 3 ketodihydrosphingosine reductase 0.0019 0.0025 0.0025
Schistosoma mansoni voltage-gated potassium channel 0.0024 0.0058 0.0054
Leishmania major hypothetical protein, conserved 0.0109 0.0678 0.0691
Echinococcus multilocularis steroid dehydrogenase 0.0019 0.0025 0.0025
Mycobacterium ulcerans carveol-like dehydrogenase 0.0019 0.0025 0.0025
Brugia malayi Heterochromatin protein 1 0.007 0.0397 0.0647
Echinococcus granulosus g protein coupled receptor 0.0054 0.0278 0.0278
Onchocerca volvulus Sepiapterin reductase homolog 0.0019 0.0025 0.0021
Echinococcus multilocularis jumonji domain containing protein 0.0042 0.0188 0.0188
Trichomonas vaginalis PIKK family atypical protein kinase 0.0036 0.0149 0.0199
Schistosoma mansoni tar DNA-binding protein 0.0062 0.0338 0.0334
Mycobacterium ulcerans cytochrome P450 185A4 Cyp185A4 0.0081 0.0476 0.1601
Toxoplasma gondii PHD-finger domain-containing protein 0.003 0.0102 0.0224
Schistosoma mansoni short chain dehydrogenase 0.0019 0.0025 0.0021
Trypanosoma brucei dihydrolipoyl dehydrogenase 0.0409 0.2878 0.2963
Echinococcus multilocularis peregrin 0.003 0.0102 0.0102
Brugia malayi larval opioid receptor 0.0054 0.0278 0.0453
Loa Loa (eye worm) hypothetical protein 0.0027 0.008 0.013
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.0586 0.4175 1
Leishmania major short chain dehydrogenase/reductase, putative 0.0019 0.0025 0.0015
Mycobacterium leprae THIOREDOXIN TRXC (TRX) (MPT46) 0.0109 0.0678 0.129
Trichomonas vaginalis conserved hypothetical protein 0.0039 0.0171 0.023
Echinococcus granulosus uncharacterized sodium dependent transporter 0.0025 0.0064 0.0064
Echinococcus multilocularis apoptosis inducing factor 1 mitochondrial 0.0109 0.0678 0.0678
Echinococcus granulosus phd:f box containing protein 0.0025 0.007 0.007
Brugia malayi glutamate synthase 0.0109 0.0678 0.1104
Echinococcus multilocularis para nitrobenzyl esterase 0.0083 0.049 0.049
Echinococcus multilocularis pyroglutamylated rfamide peptide receptor 0.0054 0.0278 0.0278
Brugia malayi neuropeptide F receptor 0.0054 0.0278 0.0453
Trichomonas vaginalis DNA helicase recq1, putative 0.0021 0.0036 0.0037
Onchocerca volvulus 0.0019 0.0025 0.0021
Trypanosoma cruzi short chain dehydrogenase, putative 0.0019 0.0025 0.0015
Trichomonas vaginalis set domain proteins, putative 0.0973 0.7004 1
Loa Loa (eye worm) hypothetical protein 0.0019 0.0025 0.0041
Loa Loa (eye worm) cytoplasmic intermediate filament protein 0.0028 0.0089 0.0145
Echinococcus granulosus retinol dehydrogenase 11 0.0019 0.0025 0.0025
Mycobacterium ulcerans 3-alpha-hydroxysteroid dehydrogenase 0.0019 0.0025 0.0025
Loa Loa (eye worm) hypothetical protein 0.0054 0.0278 0.0453
Trypanosoma cruzi short-chain dehydrogenase, putative 0.0019 0.0025 0.0015
Onchocerca volvulus 0.0054 0.0278 0.0383
Toxoplasma gondii Erv1 / Alr family protein 0.0034 0.0129 0.0289
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0054 0.0278 0.0274
Entamoeba histolytica pyrophosphate-dependent phosphofructokinase 0.003 0.01 0.0215
Schistosoma mansoni BC026374 protein (S09 family) 0.0083 0.049 0.0486
Mycobacterium tuberculosis Possible oxidoreductase 0.0019 0.0025 0.0014
Echinococcus granulosus biogenic amine 5HT receptor 0.0054 0.0278 0.0278
Loa Loa (eye worm) hypothetical protein 0.0032 0.0118 0.0192
Schistosoma mansoni sodium/chloride dependent neurotransmitter transporter 0.0025 0.0064 0.0061
Schistosoma mansoni growth hormone secretagogue receptor 0.0054 0.0278 0.0274
Mycobacterium ulcerans short chain dehydrogenase 0.0019 0.0025 0.0025
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0102 0.063 0.0642
Trypanosoma brucei trypanothione reductase 0.0579 0.4123 0.4253
Schistosoma mansoni steroid dehydrogenase 0.0019 0.0025 0.0021
Schistosoma mansoni hyperpolarization activated cyclic nucleotide-gated potassium channel 0.0021 0.0033 0.0029
Trypanosoma cruzi phosphatidylinositol kinase related protein, putative 0.0025 0.0064 0.0055
Mycobacterium ulcerans cytochrome p450 150 cyp150 0.0054 0.0279 0.0913
Brugia malayi Carboxylesterase family protein 0.0491 0.3476 0.5661
Echinococcus granulosus NADPH:adrenodoxin oxidoreductase 0.0109 0.0678 0.0678
Trypanosoma cruzi cysteine peptidase, putative 0.0066 0.0368 0.037
Schistosoma mansoni hypothetical protein 0.0054 0.0279 0.0275
Treponema pallidum oxidoreductase 0.0109 0.0678 0.1587
Echinococcus multilocularis Peptidase C19, ubiquitin carboxyl terminal hydrolase 2 0.0038 0.0164 0.0164
Mycobacterium tuberculosis Possible multi-functional enzyme with acyl-CoA-reductase activity AcrA1 0.0019 0.0025 0.0014
Brugia malayi G-protein-linked acetylcholine receptor protein 2, putative 0.0054 0.0278 0.0453
Toxoplasma gondii selenide, water dikinase 0.0109 0.0678 0.1623
Echinococcus granulosus carboxylesterase 5A 0.0491 0.3476 0.3476
Chlamydia trachomatis thioredoxin reductase 0.0109 0.0678 0.2181
Echinococcus multilocularis 7TM GPCR, rhodopsin 0.0054 0.0278 0.0278
Schistosoma mansoni steroid dehydrogenase 0.0019 0.0025 0.0021
Echinococcus multilocularis allatostatin A receptor 0.0054 0.0278 0.0278
Mycobacterium tuberculosis Probable NADPH dependent 2,4-dienoyl-CoA reductase FadH (2,4-dienoyl coenzyme A reductase) (4-enoyl-CoA reductase) 0.0109 0.0678 0.1303
Brugia malayi exodeoxyribonuclease III family protein 0.0018 0.0018 0.0029
Trypanosoma cruzi ERV/ALR sulfhydryl oxidase domain-containing protein 0.0034 0.0129 0.0123
Plasmodium vivax hypothetical protein, conserved 0.0019 0.0025 0.0036
Echinococcus granulosus ankyrin repeat and death domain containing protein 0.0028 0.0088 0.0088
Loa Loa (eye worm) hypothetical protein 0.0025 0.0064 0.0105
Brugia malayi Bloom's syndrome protein homolog 0.0021 0.0036 0.0059
Echinococcus granulosus dihydrolipoamide dehydrogenase 0.0409 0.2878 0.2878
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.005 0.0249 0.0406
Echinococcus multilocularis tachykinin peptides receptor 99D 0.0054 0.0278 0.0278
Brugia malayi 3-hydroxyacyl-CoA dehydrogenase type II 0.018 0.1199 0.1953
Loa Loa (eye worm) oxidoreductase 0.0019 0.0025 0.0041
Schistosoma mansoni sodium-dependent neurotransmitter transporter 0.0025 0.0064 0.0061
Loa Loa (eye worm) hypothetical protein 0.0025 0.0064 0.0105
Trypanosoma brucei protein kinase, putative 0.0102 0.063 0.0634
Trypanosoma cruzi 3-ketoacyl-CoA reductase, putative 0.0019 0.0025 0.0015
Schistosoma mansoni tyrosyl-DNA phosphodiesterase 0.0068 0.0377 0.0373
Mycobacterium ulcerans extragenic suppressor protein SuhB 0.0147 0.0959 0.3291
Loa Loa (eye worm) hypothetical protein 0.0019 0.0025 0.0041
Echinococcus multilocularis pyridine nucleotide disulfide oxidoreductase 0.0109 0.0678 0.0678
Loa Loa (eye worm) hypothetical protein 0.0054 0.0278 0.0453
Trypanosoma brucei NADPH:adrenodoxin oxidoreductase, mitochondrial, putative 0.0109 0.0678 0.0684
Onchocerca volvulus Glucosylceramidase homolog 0.0164 0.1081 0.1531
Trichomonas vaginalis adenylate and guanylate cyclases, putative 0.0025 0.0067 0.0081
Treponema pallidum fructose-bisphosphate aldolase 0.0586 0.4175 1
Brugia malayi G-protein coupled receptor 0.0054 0.0278 0.0453
Mycobacterium tuberculosis Possible fatty acyl-CoA reductase 0.0019 0.0025 0.0014
Schistosoma mansoni family S9 non-peptidase homologue (S09 family) 0.0083 0.049 0.0486
Brugia malayi RNA recognition motif domain containing protein 0.0062 0.0338 0.055
Trypanosoma cruzi tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0068 0.0377 0.038
Echinococcus granulosus hypothetical protein 0.0721 0.5157 0.5157
Trypanosoma cruzi ATP-dependent 6-phosphofructokinase, glycosomal 0.011 0.0685 0.0699
Mycobacterium ulcerans dehydrogenase/decarboxylase protein 0.0019 0.0025 0.0025
Loa Loa (eye worm) dehydrogenase 0.0019 0.0025 0.0041
Leishmania major phosphatidylinositol 3-related kinase, putative 0.0036 0.0149 0.0144
Trichomonas vaginalis dihydrolipoamide dehydrogenase, putative 0.0109 0.0678 0.0955
Trypanosoma cruzi cruzipain precursor, putative 0.0066 0.0368 0.037
Echinococcus granulosus carbonyl reductase 1 0.0019 0.0025 0.0025
Brugia malayi Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain containing protein 0.0301 0.2083 0.3392
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0054 0.0278 0.0274
Plasmodium vivax glutathione reductase, putative 0.0579 0.4123 1
Echinococcus multilocularis ubiquitin specific protease 41 0.0038 0.0164 0.0164
Schistosoma mansoni histamine h1 receptor 0.0054 0.0278 0.0274
Echinococcus granulosus 3 hydroxyacyl coenzyme A dehydrogenase type 2 0.018 0.1199 0.1199
Loa Loa (eye worm) hypothetical protein 0.0019 0.0025 0.0041
Toxoplasma gondii NADPH-glutathione reductase 0.0409 0.2878 0.6972
Onchocerca volvulus Alhambra homolog 0.003 0.0102 0.0132
Onchocerca volvulus 0.0025 0.0064 0.0077
Loa Loa (eye worm) hypothetical protein 0.0356 0.2487 0.405
Schistosoma mansoni amine GPCR 0.0054 0.0278 0.0274
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0147 0.0959 0.0982
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0066 0.0368 0.0363
Trypanosoma cruzi NADH dehydrogenase, putative 0.0109 0.0678 0.0691
Schistosoma mansoni bromodomain-containing nuclear protein 1 brd1 0.003 0.0102 0.0098
Echinococcus granulosus rhodopsin orphan GPCR 0.0054 0.0278 0.0278
Echinococcus granulosus cathepsin l cysteine peptidase 0.0017 0.001 0.001
Trypanosoma brucei C-8 sterol isomerase, putative 0.0356 0.2487 0.2557
Loa Loa (eye worm) oxidoreductase 0.0019 0.0025 0.0041
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0586 0.4175 0.5955
Trypanosoma cruzi cytochrome P450, putative 0.0081 0.0476 0.0482
Trypanosoma cruzi beta-ketoacyl-ACP reductase 2, putative 0.0019 0.0025 0.0015
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0038 0.0164 0.022
Schistosoma mansoni hypothetical protein 0.05 0.3544 0.3542
Trypanosoma brucei phosphatidylinositol 3-kinase tor, putative 0.0025 0.0064 0.0048
Echinococcus multilocularis Ataxin 2, N terminal,domain containing protein 0.0033 0.0126 0.0126
Mycobacterium ulcerans NADPH dependent 2,4-dienoyl-CoA reductase FadH 0.0109 0.0678 0.2308
Mycobacterium tuberculosis Probable cytochrome P450 140 Cyp140 0.0054 0.0279 0.0516
Echinococcus granulosus peptide allatostatin:somatostatin 0.0054 0.0278 0.0278
Trypanosoma cruzi 3-keto-dihydrosphingosine reductase 0.0019 0.0025 0.0015
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0025 0.0064 0.0105
Echinococcus multilocularis jumonji domain containing 1A 0.0025 0.007 0.007
Trypanosoma brucei pyridine nucleotide-disulphide oxidoreductase, putative 0.0109 0.0678 0.0684
Echinococcus granulosus g-protein coupled receptor 0.0054 0.0278 0.0278
Loa Loa (eye worm) hypothetical protein 0.0182 0.1214 0.1977
Trypanosoma brucei dihydrolipoamide dehydrogenase, point mutation 0.0997 0.7176 0.7416
Loa Loa (eye worm) solute carrier family 6 member 4 0.0146 0.0952 0.155
Mycobacterium ulcerans cytochrome P450 188A3 Cyp188A3 0.0054 0.0279 0.0913
Mycobacterium tuberculosis Probable short-chain type dehydrogenase/reductase 0.0019 0.0025 0.0014
Onchocerca volvulus 0.0083 0.049 0.0686
Loa Loa (eye worm) cysteine protease 0.0017 0.001 0.0017
Mycobacterium ulcerans fructose-bisphosphate aldolase 0.0286 0.198 0.686
Trichomonas vaginalis PIKK family atypical protein kinase 0.0036 0.0149 0.0199
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0019 0.0025 0.0025
Loa Loa (eye worm) jmjC domain-containing protein 0.0025 0.007 0.0113
Trichomonas vaginalis phosphofructokinase, putative 0.011 0.0685 0.0965
Loa Loa (eye worm) hypothetical protein 0.0054 0.0278 0.0453
Loa Loa (eye worm) hypothetical protein 0.0025 0.0064 0.0105
Schistosoma mansoni sulfide quinone reductase 0.0109 0.0678 0.0674
Toxoplasma gondii Sodium:neurotransmitter symporter family protein 0.0025 0.0064 0.0132
Trichomonas vaginalis chromobox protein, putative 0.0042 0.0193 0.0262
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0147 0.0959 0.0982
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 8 0.0038 0.0164 0.0164
Echinococcus multilocularis Polycystic kidney disease protein 0.016 0.1055 0.1055
Plasmodium falciparum ADP-dependent DNA helicase RecQ 0.0018 0.0018 0.0018
Loa Loa (eye worm) 6-phosphofructokinase 0.011 0.0685 0.1116
Echinococcus granulosus growth hormone secretagogue receptor type 1 0.0054 0.0278 0.0278
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0035 0.0141 0.0141
Loa Loa (eye worm) hypothetical protein 0.0454 0.3206 0.5221
Schistosoma mansoni inositol monophosphatase 0.0147 0.0959 0.0956
Echinococcus multilocularis mitogen activated protein kinase 3 0.0102 0.063 0.063
Trichomonas vaginalis disulfide oxidoreductase, putative 0.0109 0.0678 0.0955
Echinococcus granulosus Polycystic kidney disease protein 0.016 0.1055 0.1055
Loa Loa (eye worm) hypothetical protein 0.0054 0.0278 0.0453
Onchocerca volvulus Netrin receptor homolog 0.0028 0.0088 0.0111
Mycobacterium ulcerans 3-ketoacyl-ACP reductase 0.0019 0.0025 0.0025
Mycobacterium tuberculosis Probable cytochrome P450 130 Cyp130 0.0054 0.0279 0.0516
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0019 0.0025 0.0041
Trichomonas vaginalis soluble guanylate cyclase gcy, putative 0.0025 0.0067 0.0081
Mycobacterium tuberculosis Probable oxidoreductase 0.0019 0.0025 0.0014
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0038 0.0164 0.0267
Echinococcus multilocularis lipoxygenase domain containing protein 0.016 0.1055 0.1055
Schistosoma mansoni phosphatidylinositol 3-and 4-kinase 0.0036 0.0149 0.0146
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0054 0.0278 0.0274
Leishmania major protein kinase, putative 0.0026 0.0074 0.0066
Leishmania major quinonoid dihydropteridine reductase 0.0019 0.0025 0.0015
Toxoplasma gondii Sodium:neurotransmitter symporter family protein 0.0025 0.0064 0.0132
Mycobacterium leprae PROBABLE NADPH:ADRENODOXIN OXIDOREDUCTASE FPRB (ADRENODOXIN REDUCTASE) (AR) (FERREDOXIN-NADP(+) REDUCTASE) 0.0109 0.0678 0.129
Loa Loa (eye worm) fibroinase 0.0017 0.001 0.0017
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0038 0.0164 0.0159
Echinococcus granulosus rhodopsin orphan GPCR 0.0054 0.0278 0.0278
Schistosoma mansoni fkbp-rapamycin associated protein 0.0021 0.0033 0.0029
Brugia malayi jmjC domain containing protein 0.0096 0.0583 0.0949
Echinococcus granulosus sodium:chloride dependent neurotransmitter 0.0025 0.0064 0.0064
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription factor 0.0249 0.1708 0.1708
Echinococcus multilocularis neuropeptides capa receptor 0.0054 0.0278 0.0278
Mycobacterium ulcerans dehydrogenase/reductase 0.0019 0.0025 0.0025
Echinococcus multilocularis sulfide:quinone oxidoreductase 0.0109 0.0678 0.0678
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0586 0.4175 0.5955
Echinococcus multilocularis transient receptor potential gamma protein 0.0107 0.0668 0.0668
Mycobacterium ulcerans short chain dehydrogenase 0.0019 0.0025 0.0025
Loa Loa (eye worm) cyclic-nucleotide gated cation channel 0.0021 0.0033 0.0054
Echinococcus multilocularis muscleblind protein 0.018 0.1203 0.1203
Echinococcus multilocularis bloom syndrome protein 0.0021 0.0036 0.0036
Leishmania major ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative 0.0038 0.0164 0.0159
Mycobacterium tuberculosis Probable cytochrome P450 125 Cyp125 0.0054 0.0279 0.0516
Echinococcus multilocularis retinol dehydrogenase 11 0.0019 0.0025 0.0025
Onchocerca volvulus 0.0134 0.0865 0.1221
Brugia malayi phosphofructokinase 0.011 0.0685 0.1116
Giardia lamblia PHD finger protein 15 0.003 0.0102 0.0203
Schistosoma mansoni short chain dehydrogenase 0.0019 0.0025 0.0021
Brugia malayi Cytochrome P450 family protein 0.0081 0.0476 0.0775
Echinococcus multilocularis PHD finger protein rhinoceros 0.003 0.0102 0.0102
Trypanosoma brucei cytochrome P450, putative 0.0081 0.0476 0.0474
Brugia malayi Carboxylesterase family protein 0.0083 0.049 0.0798
Trypanosoma cruzi JmjC domain, hydroxylase, putative 0.0025 0.007 0.0061
Schistosoma mansoni phosphatidylserine receptor 0.0025 0.007 0.0066
Toxoplasma gondii 2,4-dienoyl CoA reductase 2, peroxisomal family protein 0.0019 0.0025 0.0036
Echinococcus multilocularis arachidonate 5 lipoxygenase 0.0707 0.5054 0.5054
Loa Loa (eye worm) hypothetical protein 0.0054 0.0278 0.0453
Trichomonas vaginalis disulfide oxidoreductase, putative 0.0109 0.0678 0.0955
Loa Loa (eye worm) hypothetical protein 0.0025 0.0064 0.0105
Loa Loa (eye worm) hypothetical protein 0.0146 0.0952 0.155
Leishmania major hypothetical protein, conserved 0.0019 0.0025 0.0015
Trichomonas vaginalis adenylate and guanylate cyclases, putative 0.0025 0.0067 0.0081
Echinococcus granulosus neuropeptide FF receptor 2 0.0054 0.0278 0.0278
Loa Loa (eye worm) hypothetical protein 0.0054 0.0278 0.0453
Schistosoma mansoni short chain dehydrogenase 0.0019 0.0025 0.0021
Leishmania major cathepsin L-like protease 0.0066 0.0368 0.037
Loa Loa (eye worm) Papain cysteine protease/cathepsin propeptide inhibitor-containing protein 0.0017 0.001 0.0017
Schistosoma mansoni aryl hydrocarbon receptor 0.0097 0.0591 0.0587
Mycobacterium ulcerans monoxygenase 0.0109 0.0678 0.2308
Trypanosoma brucei oxidoreductase-like protein 0.0019 0.0025 0.0007
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.1133 0.8176 0.8452
Mycobacterium tuberculosis Probable soluble pyridine nucleotide transhydrogenase SthA (STH) (NAD(P)(+) transhydrogenase [B-specific]) (nicotinamide nucleot 0.0409 0.2878 0.5645
Trichomonas vaginalis PIKK family atypical protein kinase 0.0054 0.0279 0.0384
Schistosoma mansoni hyperpolarization activated cyclic nucleotide-gated potassium channel 0.0021 0.0033 0.0029
Loa Loa (eye worm) hypothetical protein 0.018 0.1203 0.196
Trypanosoma cruzi mitogen activated protein kinase 2, putative 0.0102 0.063 0.0642
Echinococcus multilocularis carboxylesterase 5A 0.0491 0.3476 0.3476
Trypanosoma cruzi hypothetical protein, conserved 0.0109 0.0678 0.0691
Plasmodium falciparum type II NADH:ubiquinone oxidoreductase 0.0109 0.0678 0.1623
Schistosoma mansoni opsin-like receptor 0.0054 0.0278 0.0274
Trichomonas vaginalis PIKK family atypical protein kinase 0.0048 0.0231 0.0315
Brugia malayi hypothetical protein 0.0054 0.0278 0.0453
Echinococcus granulosus GPCR family 2 0.0031 0.0111 0.0111
Toxoplasma gondii target of rapamycin (TOR), putative 0.0054 0.0279 0.0654
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0031 0.0111 0.0111
Loa Loa (eye worm) hypothetical protein 0.0054 0.0278 0.0453
Schistosoma mansoni muscarinic acetylcholine (GAR) receptor 0.0054 0.0278 0.0274
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.005 0.0249 0.0249
Loa Loa (eye worm) RNA recognition domain-containing protein domain-containing protein 0.0062 0.0338 0.055
Leishmania major oxidoreductase-like protein 0.0019 0.0025 0.0015
Trypanosoma brucei short-chain dehydrogenase, putative 0.0019 0.0025 0.0007
Onchocerca volvulus 0.0054 0.0278 0.0383
Echinococcus multilocularis geminin 0.05 0.3544 0.3544
Trichomonas vaginalis PIKK family atypical protein kinase 0.0048 0.0231 0.0315
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0031 0.0111 0.0111
Trichomonas vaginalis adenylate cyclase, putative 0.0025 0.0067 0.0081
Mycobacterium ulcerans NADPH:adrenodoxin oxidoreductase FprA 0.0109 0.0678 0.2308
Schistosoma mansoni cathepsin F (C01 family) 0.0017 0.001 0.0006
Giardia lamblia Kinase, CMGC MAPK 0.0102 0.063 0.1472
Brugia malayi PAS domain containing protein 0.0097 0.0591 0.0963
Mycobacterium tuberculosis Probable cytochrome P450 124 Cyp124 0.0054 0.0279 0.0516
Mycobacterium ulcerans dihydrolipoamide dehydrogenase, LpdB 0.0409 0.2878 1
Loa Loa (eye worm) voltage and ligand gated potassium channel 0.005 0.0245 0.04
Echinococcus granulosus short transient receptor potential channel 6 0.0075 0.0434 0.0434
Onchocerca volvulus 0.0019 0.0025 0.0021
Brugia malayi Papain family cysteine protease containing protein 0.0017 0.001 0.0017
Echinococcus granulosus hypothetical protein 0.0019 0.0025 0.0025
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0019 0.0025 0.0025
Onchocerca volvulus 0.0054 0.0278 0.0383
Brugia malayi Bromodomain containing protein 0.003 0.0102 0.0167
Chlamydia trachomatis fructose-6-phosphate phosphotransferase 0.003 0.01 0.0126
Onchocerca volvulus 0.0054 0.0278 0.0383
Loa Loa (eye worm) TYRA-2 protein 0.0054 0.0278 0.0453
Loa Loa (eye worm) hypothetical protein 0.0083 0.049 0.0798
Loa Loa (eye worm) MH2 domain-containing protein 0.0116 0.0736 0.1198
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0021 0.0033 0.0033
Toxoplasma gondii NADH dehydrogenase (NDH2-II) 0.0109 0.0678 0.1623
Onchocerca volvulus 0.0097 0.059 0.0829
Trichomonas vaginalis phosphofructokinase, putative 0.003 0.01 0.0128
Mycobacterium tuberculosis Probable cytochrome P450 139 Cyp139 0.0054 0.0279 0.0516
Plasmodium falciparum amino acid transporter, putative 0.0025 0.0064 0.0132
Schistosoma mansoni short chain dehydrogenase 0.0019 0.0025 0.0021
Mycobacterium tuberculosis Probable reductase 0.041 0.2884 0.5658
Schistosoma mansoni acetylcholinesterase 0.0083 0.049 0.0486
Brugia malayi oxidoreductase 0.0019 0.0025 0.0041
Loa Loa (eye worm) G-protein coupled receptor 0.0054 0.0278 0.0453
Loa Loa (eye worm) intermediate filament protein 0.0052 0.0267 0.0435
Trypanosoma cruzi oxidoreductase-like protein, putative 0.0019 0.0025 0.0015
Trichomonas vaginalis inositol monophosphatase, putative 0.0147 0.0959 0.1357
Leishmania major pteridine reductase 1 0.0019 0.0025 0.0015
Trichomonas vaginalis PIKK family atypical protein kinase 0.0038 0.0163 0.0218
Trypanosoma brucei Lanosterol 14-alpha demethylase 0.0201 0.1355 0.1386
Trichomonas vaginalis PIKK family atypical protein kinase 0.0056 0.0296 0.0408
Brugia malayi Cathepsin L-like precursor 0.0017 0.001 0.0017
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0019 0.0025 0.0041
Trypanosoma cruzi Phosphatidylinositol 3-kinase tor2 0.0065 0.0361 0.0363
Echinococcus multilocularis FKBP12 rapamycin complex associated protein 0.0065 0.0361 0.0361
Loa Loa (eye worm) oxidoreductase 0.0019 0.0025 0.0041
Echinococcus multilocularis g protein coupled receptor 0.0054 0.0278 0.0278
Echinococcus granulosus fmrfamide receptor 0.0054 0.0278 0.0278
Mycobacterium leprae Probable fructose bisphosphate aldolase Fba 0.0286 0.198 0.3864
Schistosoma mansoni single-minded 0.0097 0.0591 0.0587
Echinococcus multilocularis G-protein coupled receptor, putative 0.0054 0.0278 0.0278
Echinococcus granulosus lipoxygenase domain containing protein 0.016 0.1055 0.1055
Mycobacterium ulcerans short chain dehydrogenase 0.0019 0.0025 0.0025
Echinococcus multilocularis carbonyl reductase 1 0.0019 0.0025 0.0025
Loa Loa (eye worm) hepatopoietin HPO2 0.0034 0.0129 0.021
Mycobacterium leprae PROBABLE 6-PHOSPHOFRUCTOKINASE PFKA (PHOSPHOHEXOKINASE) (PHOSPHOFRUCTOKINASE) 0.011 0.0685 0.1305
Loa Loa (eye worm) hypothetical protein 0.0054 0.0278 0.0453
Schistosoma mansoni glutamate synthase 0.0109 0.0678 0.0674
Schistosoma mansoni retinal dehydrogenase 0.0019 0.0025 0.0021
Schistosoma mansoni polycystin 1-related 0.016 0.1055 0.1051
Loa Loa (eye worm) hypothetical protein 0.0054 0.0278 0.0453
Loa Loa (eye worm) hypothetical protein 0.003 0.0102 0.0167
Loa Loa (eye worm) oxidoreductase 0.0019 0.0025 0.0041
Wolbachia endosymbiont of Brugia malayi thioredoxin reductase 0.0109 0.0678 0.2308
Echinococcus granulosus sodium dependent neurotransmitter transporter 0.0025 0.0064 0.0064
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0054 0.0278 0.0278
Trichomonas vaginalis glucosylceramidase, putative 0.0173 0.1146 0.1623
Trichomonas vaginalis PIKK family atypical protein kinase 0.0038 0.0163 0.0218
Echinococcus multilocularis RUN 0.016 0.1055 0.1055
Schistosoma mansoni norepinephrine/norepinephrine transporter 0.0025 0.0064 0.0061
Toxoplasma gondii oxidoreductase, short chain dehydrogenase/reductase family protein 0.0019 0.0025 0.0036
Leishmania major mitogen activated protein kinase, putative,map kinase, putative 0.0102 0.063 0.0642
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0031 0.0111 0.0111
Brugia malayi G protein-coupled receptor F59B2.13 0.0054 0.0278 0.0453
Schistosoma mansoni norepinephrine/norepinephrine transporter 0.0025 0.0064 0.0061
Schistosoma mansoni inositol monophosphatase 0.0147 0.0959 0.0956
Loa Loa (eye worm) latrophilin receptor protein 2 0.0031 0.0111 0.018
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0054 0.0278 0.0278
Loa Loa (eye worm) hypothetical protein 0.0019 0.0025 0.0041
Plasmodium vivax AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0018 0.0018 0.0019
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0031 0.0111 0.0111
Echinococcus multilocularis transient receptor potential ion channel A 0.0092 0.0553 0.0553
Mycobacterium leprae Probable NADPH:adrenodoxin oxidoreductase FprA (NADPH-FERREDOXIN REDUCTASE) 0.0109 0.0678 0.129
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0997 0.7176 0.7418
Plasmodium falciparum phd finger protein, putative 0.003 0.0102 0.0224
Echinococcus multilocularis 6 phosphofructokinase 0.011 0.0685 0.0685
Loa Loa (eye worm) oxidoreductase 0.0019 0.0025 0.0041
Echinococcus multilocularis serotonin receptor 0.0172 0.1139 0.1139
Loa Loa (eye worm) hypothetical protein 0.0031 0.0109 0.0178
Echinococcus granulosus tm gpcr rhodopsin 0.0854 0.6133 0.6133
Schistosoma mansoni transient receptor potential channel 0.0107 0.0668 0.0665
Onchocerca volvulus 0.0054 0.0278 0.0383
Echinococcus multilocularis somatostatin receptor 0.0054 0.0278 0.0278
Echinococcus multilocularis rhodopsin orphan GPCR 0.0054 0.0278 0.0278
Brugia malayi Retinol dehydrogenase 12 0.0019 0.0025 0.0041
Schistosoma mansoni intermediate filament proteins 0.0052 0.0267 0.0263
Loa Loa (eye worm) hypothetical protein 0.0146 0.0952 0.155
Loa Loa (eye worm) hypothetical protein 0.0054 0.0278 0.0453
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0021 0.0033 0.0033
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0019 0.0025 0.0041
Loa Loa (eye worm) gonadotropin-releasing hormone receptor 2 0.0054 0.0278 0.0453
Schistosoma mansoni sodium-dependent amino acid transporter 0.0025 0.0064 0.0061
Loa Loa (eye worm) serotonin transporter b 0.0146 0.0952 0.155
Echinococcus multilocularis neuropeptide receptor A26 0.0054 0.0278 0.0278
Plasmodium falciparum FAD-linked sulfhydryl oxidase ERV1, putative 0.0034 0.0129 0.0289
Mycobacterium ulcerans flavoprotein disulfide reductase 0.0409 0.2878 1
Loa Loa (eye worm) tyrosyl-DNA phosphodiesterase 0.0068 0.0377 0.0614
Onchocerca volvulus 0.0083 0.049 0.0686
Schistosoma mansoni jumonji domain containing protein 0.0025 0.007 0.0066
Schistosoma mansoni adenoreceptor 0.0054 0.0278 0.0274
Echinococcus granulosus neuropeptide receptor 0.0054 0.0278 0.0278
Brugia malayi Serotonin receptor 0.0054 0.0278 0.0453
Echinococcus granulosus lysine specific demethylase 6a 0.0025 0.007 0.007
Echinococcus multilocularis conserved hypothetical protein 0.0019 0.0025 0.0025
Trypanosoma cruzi beta-ketoacyl-ACP reductase 2, putative 0.0019 0.0025 0.0015
Loa Loa (eye worm) hypothetical protein 0.0054 0.0278 0.0453
Echinococcus granulosus 7TM GPCR rhodopsin 0.0054 0.0278 0.0278
Mycobacterium ulcerans cytochrome P450 150A6 Cyp150A6 0.0054 0.0279 0.0913
Echinococcus granulosus PHD finger protein rhinoceros 0.003 0.0102 0.0102
Trichomonas vaginalis PIKK family atypical protein kinase 0.0045 0.0214 0.0291
Loa Loa (eye worm) hypothetical protein 0.0025 0.0064 0.0105
Loa Loa (eye worm) jmjC domain-containing protein 0.0025 0.007 0.0113
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0019 0.0025 0.0025
Brugia malayi AKH receptor 0.0054 0.0278 0.0453
Schistosoma mansoni sodium/chloride dependent neurotransmitter transporter 0.0025 0.0064 0.0061
Loa Loa (eye worm) G-protein-linked acetylcholine receptor protein 2 0.0054 0.0278 0.0453
Loa Loa (eye worm) hypothetical protein 0.0023 0.005 0.0082
Echinococcus granulosus cathepsin L cysteine proteinase 0.0017 0.001 0.001
Trichomonas vaginalis PIKK family atypical protein kinase 0.0038 0.0163 0.0218
Onchocerca volvulus 0.0019 0.0025 0.0021
Onchocerca volvulus 0.0054 0.0278 0.0383
Echinococcus granulosus acetylcholinesterase 0.0491 0.3476 0.3476
Echinococcus granulosus carbonyl reductase 1 0.0019 0.0025 0.0025
Mycobacterium ulcerans ketoacyl reductase 0.0019 0.0025 0.0025
Onchocerca volvulus 0.0019 0.0025 0.0021
Leishmania major hypothetical protein, conserved 0.0019 0.0025 0.0015
Echinococcus granulosus intermediate filament protein 0.0052 0.0267 0.0267
Leishmania major hypothetical protein, conserved 0.0034 0.0129 0.0123
Brugia malayi hypothetical protein 0.0035 0.0141 0.023
Echinococcus multilocularis 3 hydroxyacyl coenzyme A dehydrogenase type 2 0.018 0.1199 0.1199
Mycobacterium tuberculosis Possible dehydrogenase/reductase 0.0109 0.0678 0.1303
Brugia malayi Carboxylesterase family protein 0.0083 0.049 0.0798
Echinococcus granulosus tm gpcr rhodopsin 0.0054 0.0278 0.0278
Brugia malayi Augmenter of liver regeneration 0.0034 0.0129 0.021
Trichomonas vaginalis glucosylceramidase, putative 0.0164 0.1081 0.1531
Leishmania major quinonoid dihydropteridine reductase 0.0019 0.0025 0.0015
Schistosoma mansoni neuropeptide F-like receptor 0.0054 0.0278 0.0274
Mycobacterium leprae DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE 0.0711 0.5084 1
Loa Loa (eye worm) hypothetical protein 0.0067 0.0375 0.0611
Schistosoma mansoni thyrotropin-releasing hormone receptor 0.0054 0.0278 0.0274
Trypanosoma cruzi pyridine nucleotide-disulphide oxidoreductase, putative 0.0109 0.0678 0.0691
Mycobacterium ulcerans dihydrolipoamide dehydrogenase 0.0409 0.2878 1
Toxoplasma gondii hypothetical protein 0.0025 0.0064 0.0132
Trypanosoma cruzi STE/STE11 serine/threonine-protein kinase, putative 0.0026 0.0074 0.0066
Brugia malayi hypothetical protein 0.0048 0.0232 0.0378
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0036 0.0149 0.0243
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0054 0.0278 0.0274
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0054 0.0278 0.0278
Trichomonas vaginalis PIKK family atypical protein kinase 0.0056 0.0296 0.0408
Trichomonas vaginalis PIKK family atypical protein kinase 0.0054 0.0279 0.0384
Trichomonas vaginalis chromobox protein, putative 0.007 0.0397 0.0553
Schistosoma mansoni hypothetical protein 0.016 0.1055 0.1051
Mycobacterium ulcerans ferredoxin reductase 0.0109 0.0678 0.2308
Plasmodium falciparum dihydrolipoyl dehydrogenase, apicoplast 0.0409 0.2878 0.6972
Echinococcus multilocularis lamin 0.0052 0.0267 0.0267
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0054 0.0278 0.0274
Loa Loa (eye worm) hypothetical protein 0.0172 0.1139 0.1855
Echinococcus granulosus RUN 0.016 0.1055 0.1055
Echinococcus granulosus 6 phosphofructokinase 0.011 0.0685 0.0685
Plasmodium vivax hypothetical protein, conserved 0.003 0.0102 0.0224
Onchocerca volvulus 0.0052 0.0267 0.0367
Trypanosoma brucei Phosphatidylinositol 3-kinase tor1 0.0065 0.0361 0.0355
Toxoplasma gondii pyruvate dehydrogenase complex subunit PDH-E3II 0.0409 0.2878 0.6972
Brugia malayi hypothetical protein 0.0054 0.0278 0.0453
Toxoplasma gondii hypothetical protein 0.0025 0.0064 0.0132
Echinococcus multilocularis sodium and chloride dependent glycine 0.0025 0.0064 0.0064
Echinococcus multilocularis ankyrin repeat and death domain containing protein 0.0028 0.0088 0.0088
Schistosoma mansoni cathepsin F (C01 family) 0.0017 0.001 0.0006
Trypanosoma brucei hypothetical protein, conserved 0.0109 0.0678 0.0684
Echinococcus multilocularis cyclic nucleotide gated cation channel alpha 3 0.0021 0.0033 0.0033
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0038 0.0164 0.0159
Loa Loa (eye worm) neuropeptide F receptor 0.0054 0.0278 0.0453
Echinococcus multilocularis Transcription factor, JmjC domain containing protein 0.0157 0.1035 0.1035
Loa Loa (eye worm) hypothetical protein 0.0019 0.0025 0.0041
Plasmodium vivax multidomain scavenger receptor, putative 0.016 0.1055 0.254
Mycobacterium ulcerans NADH dehydrogenase 0.0109 0.0678 0.2308
Echinococcus granulosus FAD linked sulfhydryl oxidase ALR 0.0034 0.0129 0.0129
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0019 0.0025 0.0025
Entamoeba histolytica phosphofructokinase, putative 0.011 0.0685 0.1621
Toxoplasma gondii oxidoreductase, putative 0.0019 0.0025 0.0036
Loa Loa (eye worm) hypothetical protein 0.0054 0.0278 0.0453
Echinococcus granulosus 7tm_1 domain containing protein 0.0054 0.0278 0.0278
Echinococcus multilocularis voltage gated potassium channel 0.0024 0.0058 0.0058
Loa Loa (eye worm) hypothetical protein 0.0146 0.0952 0.155
Onchocerca volvulus 0.0019 0.0025 0.0021
Trichomonas vaginalis PIKK family atypical protein kinase 0.0045 0.0214 0.0291
Mycobacterium tuberculosis Probable short-chain type dehydrogenase/reductase 0.0019 0.0025 0.0014
Loa Loa (eye worm) hypothetical protein 0.0054 0.0278 0.0453
Echinococcus multilocularis tar DNA binding protein 0.0062 0.0338 0.0338
Loa Loa (eye worm) doublecortin family protein 0.016 0.1055 0.1718
Brugia malayi hypothetical protein 0.0054 0.0278 0.0453
Leishmania major dihydrolipoamide dehydrogenase, putative 0.1337 0.9671 1
Trypanosoma cruzi NADPH:adrenodoxin oxidoreductase, mitochondrial, putative 0.0109 0.0678 0.0691
Trypanosoma cruzi 2,4-dienoyl-coa reductase-like protein, putative 0.0109 0.0678 0.0691
Trichomonas vaginalis glucosylceramidase, putative 0.0164 0.1081 0.1531
Trichomonas vaginalis short-chain dehydrogenase, putative 0.0019 0.0025 0.0021
Mycobacterium ulcerans short chain dehydrogenase 0.0019 0.0025 0.0025
Plasmodium falciparum JmjC domain-containing protein, putative 0.0025 0.007 0.0144
Schistosoma mansoni transient receptor potential channel 0.0075 0.0434 0.043
Brugia malayi Cathepsin L-like precursor 0.0017 0.001 0.0017
Trichomonas vaginalis glucosylceramidase, putative 0.0249 0.1709 0.2429
Trypanosoma cruzi phosphatidylinositol 3-related kinase, putative 0.0036 0.0149 0.0144
Mycobacterium tuberculosis NAD(P)H quinone reductase LpdA 0.0711 0.5084 1
Brugia malayi bHLH-PAS transcription factor 0.0072 0.0407 0.0663
Brugia malayi PHD-finger family protein 0.003 0.0102 0.0167
Brugia malayi hypothetical protein 0.0074 0.0424 0.0691
Schistosoma mansoni family S9 non-peptidase homologue (S09 family) 0.0083 0.049 0.0486
Brugia malayi Intermediate filament tail domain containing protein 0.0052 0.0267 0.0435
Brugia malayi Tachykinin-like peptides receptor 99D 0.0054 0.0278 0.0453
Mycobacterium ulcerans short chain dehydrogenase 0.0019 0.0025 0.0025
Giardia lamblia Glutamate synthase 0.0109 0.0678 0.1587
Loa Loa (eye worm) hypothetical protein 0.0054 0.0278 0.0453
Brugia malayi Dopamine receptor protein 1, putative (partial) 0.0054 0.0278 0.0453
Mycobacterium tuberculosis Putative ferredoxin reductase 0.041 0.2884 0.5658
Echinococcus multilocularis survival motor neuron protein 1 0.0474 0.335 0.335
Mycobacterium ulcerans cytochrome P450 125A7 Cyp125A7 0.0054 0.0279 0.0913
Schistosoma mansoni neuropeptide receptor 0.0054 0.0278 0.0274
Echinococcus granulosus jumonji domain containing protein 0.0042 0.0188 0.0188
Trichomonas vaginalis conserved hypothetical protein 0.0025 0.0067 0.0081
Onchocerca volvulus 0.0025 0.0067 0.0081
Schistosoma mansoni ancient conserved domain protein 2 (cyclin m2) 0.0054 0.0278 0.0274
Treponema pallidum NADH oxidase 0.0409 0.2878 0.6879
Mycobacterium ulcerans cytochrome P450 126A3 Cyp126A3 0.0054 0.0279 0.0913
Trypanosoma cruzi pyridine nucleotide-disulphide oxidoreductase, putative 0.0109 0.0678 0.0691
Echinococcus granulosus Peptidase C19 ubiquitin carboxyl terminal hydrolase 2 0.0038 0.0164 0.0164
Echinococcus granulosus netrin receptor unc 5 0.0028 0.0088 0.0088
Trypanosoma cruzi phosphatidylinositol 3-related kinase, putative 0.0036 0.0149 0.0144
Schistosoma mansoni short chain dehydrogenase 0.0019 0.0025 0.0021
Schistosoma mansoni chromobox protein 0.007 0.0397 0.0394
Echinococcus granulosus chromobox protein 1 0.007 0.0397 0.0397
Brugia malayi cytochrome P450 0.0054 0.0279 0.0455
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.1133 0.8176 0.8453
Echinococcus multilocularis cathepsin L cysteine protease 0.0017 0.001 0.001
Schistosoma mansoni lipoxygenase 0.0707 0.5054 0.5052
Echinococcus granulosus sulfide:quinone oxidoreductase 0.0109 0.0678 0.0678
Giardia lamblia Glycerol-3-phosphate dehydrogenase 0.0109 0.0678 0.1587
Mycobacterium tuberculosis NADPH:adrenodoxin oxidoreductase FprA (NADPH-ferredoxin reductase) 0.0109 0.0678 0.1303
Brugia malayi G-protein coupled receptor 0.0054 0.0278 0.0453
Echinococcus granulosus voltage gated potassium channel 0.0024 0.0058 0.0058
Loa Loa (eye worm) hypothetical protein 0.0054 0.0278 0.0453
Loa Loa (eye worm) hypothetical protein 0.0028 0.009 0.0146
Mycobacterium tuberculosis Probable 6-phosphofructokinase PfkA (phosphohexokinase) (phosphofructokinase) 0.011 0.0685 0.1318
Schistosoma mansoni biogenic amine (5HT) receptor 0.0054 0.0278 0.0274
Trypanosoma cruzi hypothetical protein, conserved 0.0019 0.0025 0.0015
Loa Loa (eye worm) hypothetical protein 0.0083 0.049 0.0798
Onchocerca volvulus 0.0054 0.0278 0.0383
Trichomonas vaginalis disulfide oxidoreductase, putative 0.0109 0.0678 0.0955
Schistosoma mansoni jumonji/arid domain-containing protein 0.0096 0.0583 0.0579
Echinococcus granulosus neuropeptide Y receptor 0.0054 0.0278 0.0278
Brugia malayi RE15519p 0.0054 0.0278 0.0453
Brugia malayi hypothetical protein 0.0054 0.0278 0.0453
Mycobacterium ulcerans NADH dehydrogenase Ndh 0.0109 0.0678 0.2308
Trypanosoma cruzi target of rapamycin kinase 3 0.0056 0.0296 0.0296
Schistosoma mansoni neuropeptide F-like receptor 0.0054 0.0278 0.0274
Entamoeba histolytica hypothetical protein 0.0035 0.0141 0.0314
Schistosoma mansoni hypothetical protein 0.0109 0.0678 0.0674
Loa Loa (eye worm) heterochromatin protein 1 0.007 0.0397 0.0647
Echinococcus multilocularis phd:f box containing protein 0.0025 0.007 0.007
Mycobacterium tuberculosis Probable short-chain type dehydrogenase/reductase 0.0019 0.0025 0.0014
Echinococcus multilocularis rhodopsin orphan GPCR 0.0054 0.0278 0.0278
Echinococcus granulosus carbonyl reductase 1 0.0019 0.0025 0.0025
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.005 0.0249 0.0245
Mycobacterium tuberculosis Probable cytochrome P450 123 Cyp123 0.0054 0.0279 0.0516
Loa Loa (eye worm) hypothetical protein 0.0054 0.0278 0.0453
Trypanosoma brucei ERV/ALR sulfhydryl oxidase domain-containing protein 0.0034 0.0129 0.0115
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0066 0.0368 0.0363
Echinococcus granulosus aryl hydrocarbon receptor 0.0025 0.0067 0.0067
Brugia malayi hypothetical protein 0.0474 0.335 0.5456
Loa Loa (eye worm) Sodium:neurotransmitter symporter family protein 0.0025 0.0064 0.0105
Trichomonas vaginalis disulfide oxidoreductase, putative 0.0109 0.0678 0.0955
Onchocerca volvulus 0.0019 0.0025 0.0021
Echinococcus multilocularis TRP (transient receptor potential) channel 0.0048 0.0233 0.0233
Loa Loa (eye worm) hypothetical protein 0.0054 0.0278 0.0453
Schistosoma mansoni amine GPCR 0.0534 0.3791 0.3789
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0019 0.0025 0.0041
Loa Loa (eye worm) O-glycosyl hydrolase family 30 protein 0.0249 0.1709 0.2784
Toxoplasma gondii exonuclease III APE 0.0018 0.0018 0.0019
Loa Loa (eye worm) hypothetical protein 0.0025 0.0064 0.0105
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0054 0.0278 0.0274
Echinococcus granulosus geminin 0.05 0.3544 0.3544
Giardia lamblia Oxidoreductase, short chain dehydrogenase/reductase family 0.0019 0.0025 0.0017
Brugia malayi Inositol-1 0.0147 0.0959 0.1562
Leishmania major cytochrome p450-like protein 0.0081 0.0476 0.0482
Echinococcus multilocularis mitogen activated protein kinase 0.0102 0.063 0.063
Loa Loa (eye worm) hypothetical protein 0.0028 0.0088 0.0143
Mycobacterium ulcerans short chain dehydrogenase 0.0019 0.0025 0.0025
Leishmania major hypothetical protein, conserved 0.0074 0.0424 0.0428
Trichomonas vaginalis short-chain dehydrogenase, putative 0.0019 0.0025 0.0021
Mycobacterium ulcerans thioredoxin reductase TrxB2 0.0109 0.0678 0.2308
Brugia malayi Cathepsin L-like precursor 0.0017 0.001 0.0017
Echinococcus granulosus sodium channel protein 0.0117 0.0743 0.0743
Leishmania major target of rapamycin kinase (TOR) kinase 3 0.0056 0.0296 0.0296
Leishmania major C-8 sterol isomerase-like protein 0.0356 0.2487 0.2563
Leishmania major apurinic/apyrimidinic endonuclease-redox protein 0.0018 0.0018 0.0008
Mycobacterium tuberculosis Possible cytochrome P450 126 Cyp126 0.0054 0.0279 0.0516
Trypanosoma cruzi NADH dehydrogenase, putative 0.0109 0.0678 0.0691
Mycobacterium tuberculosis Probable short-chain type dehydrogenase/reductase 0.0019 0.0025 0.0014
Trypanosoma brucei FAT domain/Rapamycin binding domain/Phosphatidylinositol 3- and 4-kinase, putative 0.0032 0.0115 0.0101
Echinococcus granulosus G protein coupled 5 hydroxytryptamine receptor 0.0054 0.0278 0.0278
Echinococcus granulosus chromobox protein 1 0.007 0.0397 0.0397
Plasmodium vivax 6-phosphofructokinase, putative 0.003 0.01 0.0218
Toxoplasma gondii LsmAD domain-containing protein 0.0074 0.0424 0.1006
Loa Loa (eye worm) hypothetical protein 0.0067 0.0375 0.061
Entamoeba histolytica dihydropyrimidine dehydrogenase, putative 0.0109 0.0678 0.1603
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0066 0.0368 0.0363
Schistosoma mansoni short chain dehydrogenase 0.0019 0.0025 0.0021
Loa Loa (eye worm) hypothetical protein 0.0025 0.007 0.0113
Loa Loa (eye worm) CMGC/MAPK/ERK1 protein kinase 0.0102 0.063 0.1026
Onchocerca volvulus 0.0054 0.0278 0.0383
Brugia malayi Transient-receptor-potential like protein 0.0048 0.0233 0.0379
Loa Loa (eye worm) dehydrogenase 0.0019 0.0025 0.0041
Loa Loa (eye worm) phosphofructokinase 0.011 0.0685 0.1116
Toxoplasma gondii CMGC kinase, MAPK family (ERK) MAPK-1 0.0102 0.063 0.1507
Trypanosoma cruzi PAB1-binding protein , putative 0.0074 0.0424 0.0428
Echinococcus multilocularis JmjC domain containing protein 4 0.0025 0.007 0.007
Loa Loa (eye worm) TAR-binding protein 0.0062 0.0338 0.055
Loa Loa (eye worm) cytochrome P450 family protein 0.0081 0.0476 0.0775
Brugia malayi bZIP transcription factor family protein 0.0249 0.1708 0.2782
Brugia malayi Cathepsin L-like precursor 0.0017 0.001 0.0017
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0017 0.001 0.0017
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0054 0.0278 0.0274
Echinococcus granulosus pyridine nucleotide disulfide oxidoreductase 0.0109 0.0678 0.0678
Echinococcus granulosus jun protein 0.0249 0.1708 0.1708
Schistosoma mansoni hypothetical protein 0.0067 0.0375 0.0371
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0409 0.2878 0.2968
Mycobacterium ulcerans cytochrome P450 142A3 Cyp142A3 0.0054 0.0279 0.0913
Brugia malayi hypothetical protein 0.0054 0.0278 0.0453
Onchocerca volvulus 0.0019 0.0025 0.0021
Brugia malayi D-beta-hydroxybutyrate dehydrogenase, mitochondrial precursor 0.0019 0.0025 0.0041
Loa Loa (eye worm) hypothetical protein 0.0021 0.0033 0.0054
Echinococcus granulosus apoptosis inducing factor 1 mitochondrial 0.0109 0.0678 0.0678
Trichomonas vaginalis CMGC family protein kinase 0.0102 0.063 0.0886
Schistosoma mansoni family S9 non-peptidase homologue (S09 family) 0.0491 0.3476 0.3473
Schistosoma mansoni sodium/chloride dependent transporter 0.0026 0.0071 0.0067
Echinococcus multilocularis rhodopsin orphan GPCR 0.0054 0.0278 0.0278
Schistosoma mansoni hypothetical protein 0.005 0.0249 0.0245
Echinococcus granulosus FKBP12 rapamycin complex associated protein 0.0065 0.0361 0.0361
Mycobacterium ulcerans cytochrome P450 108B4 Cyp108B4 0.0054 0.0279 0.0913
Trypanosoma brucei short-chain dehydrogenase, putative 0.0019 0.0025 0.0007
Toxoplasma gondii oxidoreductase, short chain dehydrogenase/reductase family protein 0.0019 0.0025 0.0036
Mycobacterium tuberculosis Probable NADH dehydrogenase Ndh 0.041 0.2884 0.5658
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0123 0.078 0.0777
Echinococcus multilocularis Jumonji, AT rich interactive domain 1B 0.0025 0.007 0.007
Trichomonas vaginalis dihydropyrimidine dehydrogenase, putative 0.0109 0.0678 0.0955
Trichomonas vaginalis glucosylceramidase, putative 0.0164 0.1081 0.1531
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0038 0.0164 0.022
Loa Loa (eye worm) hypothetical protein 0.0454 0.3206 0.5221
Loa Loa (eye worm) thioredoxin reductase 0.0579 0.4123 0.6716
Trypanosoma brucei beta-ketoacyl-ACP reductase 3, putative 0.0019 0.0025 0.0007
Schistosoma mansoni short chain dehydrogenase 0.0019 0.0025 0.0021
Trichomonas vaginalis PIKK family atypical protein kinase 0.0065 0.0361 0.0501
Entamoeba histolytica 3-ketodihydrosphingosine reductase protein, putative 0.0019 0.0025 0.0036
Loa Loa (eye worm) carboxylesterase 0.0491 0.3476 0.5661
Plasmodium falciparum ATP-dependent 6-phosphofructokinase 0.003 0.01 0.0218
Loa Loa (eye worm) hypothetical protein 0.0059 0.0318 0.0519
Entamoeba histolytica NAD(FAD)-dependent dehydrogenase, putative 0.0109 0.0678 0.1603
Mycobacterium tuberculosis Probable short-chain dehydrogenase/reductase 0.0019 0.0025 0.0014
Trichomonas vaginalis glucosylceramidase, putative 0.0164 0.1081 0.1531
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0019 0.0025 0.0041
Trypanosoma cruzi phosphatidylinositol kinase related protein, putative 0.0031 0.0111 0.0105
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0147 0.0959 0.1357
Trypanosoma cruzi quinonoid dihydropteridine reductase, putative 0.0019 0.0025 0.0015
Echinococcus multilocularis sex peptide receptor 0.0054 0.0278 0.0278
Loa Loa (eye worm) hypothetical protein 0.0019 0.0025 0.0041
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0065 0.0361 0.0587
Trichomonas vaginalis PIKK family atypical protein kinase 0.0054 0.0279 0.0384
Mycobacterium ulcerans aldehyde dehydrogenase 0.0122 0.0774 0.2643
Mycobacterium tuberculosis Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB 0.041 0.2884 0.5658
Trypanosoma cruzi mitogen activated protein kinase 4, putative 0.0102 0.063 0.0642
Loa Loa (eye worm) hypothetical protein 0.0025 0.0067 0.0109
Echinococcus multilocularis NADPH:adrenodoxin oxidoreductase 0.0109 0.0678 0.0678
Echinococcus multilocularis glutamate synthase 0.0109 0.0678 0.0678
Brugia malayi Dehydrogenases, short chain protein 30 0.0019 0.0025 0.0041
Echinococcus granulosus hyperpolarization activated cyclic 0.0021 0.0033 0.0033
Mycobacterium ulcerans cytochrome P450 189A7 Cyp189A7 0.0054 0.0279 0.0913
Schistosoma mansoni ap endonuclease 0.0018 0.0018 0.0014
Echinococcus granulosus lipoxygenase domain containing protein 0.016 0.1055 0.1055
Loa Loa (eye worm) inositol-1 0.0147 0.0959 0.1562
Loa Loa (eye worm) hypothetical protein 0.0025 0.007 0.0113
Trypanosoma cruzi 3-ketoacyl-CoA reductase, putative 0.0019 0.0025 0.0015
Schistosoma mansoni steroid dehydrogenase 0.0019 0.0025 0.0021
Loa Loa (eye worm) programmed cell death 8 0.0109 0.0678 0.1104
Plasmodium vivax 6-phosphofructokinase, putative 0.003 0.01 0.0218
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0019 0.0025 0.0041
Echinococcus multilocularis carbonyl reductase 1 0.0019 0.0025 0.0025
Echinococcus granulosus sex peptide receptor 0.0054 0.0278 0.0278
Echinococcus granulosus hypothetical protein 0.0019 0.0025 0.0025
Trichomonas vaginalis PIKK family atypical protein kinase 0.0021 0.0033 0.0033
Schistosoma mansoni 60S ribosomal protein L21 0.0019 0.0023 0.0019
Trichomonas vaginalis chromobox protein, putative 0.007 0.0397 0.0553
Loa Loa (eye worm) hypothetical protein 0.0054 0.0278 0.0453
Schistosoma mansoni norepinephrine/norepinephrine transporter 0.0146 0.0952 0.0948
Echinococcus multilocularis inositol monophosphatase 1 0.0147 0.0959 0.0959
Mycobacterium tuberculosis Possible iron-regulated short-chain dehydrogenase/reductase 0.0019 0.0025 0.0014
Schistosoma mansoni hypothetical protein 0.0054 0.0278 0.0274
Brugia malayi Cathepsin L-like precursor 0.0017 0.001 0.0017
Schistosoma mansoni hypothetical protein 0.0031 0.0111 0.0107
Schistosoma mansoni tar DNA-binding protein 0.0062 0.0338 0.0334
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0019 0.0025 0.0041
Mycobacterium tuberculosis Probable short-chain type dehydrogenase/reductase 0.018 0.1199 0.2331
Brugia malayi glutathione reductase 0.0579 0.4123 0.6716
Wolbachia endosymbiont of Brugia malayi NADPH-dependent glutamate synthase beta chain 0.0109 0.0678 0.2308
Echinococcus granulosus dro:myosuppressin receptor 0.0054 0.0278 0.0278
Echinococcus granulosus cathepsin l1 0.0017 0.001 0.001
Echinococcus granulosus calcium activated potassium channel 0.0017 0.0005 0.0005
Trichomonas vaginalis glucosylceramidase, putative 0.0164 0.1081 0.1531
Brugia malayi MH2 domain containing protein 0.0116 0.0736 0.1198
Trichomonas vaginalis glucosylceramidase, putative 0.0249 0.1709 0.2429
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.005 0.0249 0.0249
Schistosoma mansoni 3-keto-dihydrosphingosine reductase 0.0019 0.0025 0.0021
Loa Loa (eye worm) G-protein coupled receptor 0.0054 0.0278 0.0453
Schistosoma mansoni carbonyl reductase 0.0019 0.0025 0.0021
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0098 0.0603 0.0982
Schistosoma mansoni disulfide oxidoreductase 0.0109 0.0678 0.0674
Schistosoma mansoni steroid dehydrogenase 0.0019 0.0025 0.0021
Toxoplasma gondii pyridine nucleotide-disulfide oxidoreductase domain-containing protein 0.0109 0.0678 0.1623
Loa Loa (eye worm) glutathione reductase 0.0579 0.4123 0.6716
Entamoeba histolytica hypothetical protein 0.0035 0.0141 0.0314
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.005 0.0249 0.0245
Leishmania major cytochrome p450-like protein 0.0054 0.0279 0.0278
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0066 0.0368 0.0363
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0034 0.013 0.0171
Trypanosoma brucei NADH dehydrogenase 0.0109 0.0678 0.0684
Toxoplasma gondii non-proton pumping type-II NADH dehydrogenase I 0.0109 0.0678 0.1623
Onchocerca volvulus Dehydrogenase\/reductase SDR family member 13 homolog 0.0019 0.0025 0.0021
Leishmania major NADH dehydrogenase, putative 0.0109 0.0678 0.0691
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0054 0.0278 0.0274
Echinococcus granulosus sodium and chloride dependent glycine 0.0025 0.0064 0.0064
Echinococcus multilocularis tyrosyl DNA phosphodiesterase 1 0.0068 0.0377 0.0377
Brugia malayi putative neuropeptide receptor 0.0054 0.0278 0.0453
Schistosoma mansoni tar DNA-binding protein 0.0062 0.0338 0.0334
Loa Loa (eye worm) short chain dehydrogenase/reductase family oxidoreductase 0.0019 0.0025 0.0041
Schistosoma mansoni jumonji domain containing protein 0.0137 0.0888 0.0884
Brugia malayi Latrophilin receptor protein 2 0.0031 0.0111 0.018
Toxoplasma gondii oxidoreductase, short chain dehydrogenase/reductase family protein 0.0019 0.0025 0.0036
Wolbachia endosymbiont of Brugia malayi fructose-1,6-bisphosphatase 0.0147 0.0959 0.3291
Trichomonas vaginalis DNA helicase recq, putative 0.0021 0.0036 0.0037
Trichomonas vaginalis short-chain dehydrogenase, putative 0.0019 0.0025 0.0021
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0019 0.0025 0.0025
Brugia malayi Cytochrome P450 family protein 0.0093 0.0562 0.0915
Loa Loa (eye worm) 5-hydroxytryptamine 2C receptor 0.0054 0.0278 0.0453
Loa Loa (eye worm) hypothetical protein 0.0025 0.0068 0.0111
Mycobacterium ulcerans cytochrome P450 51B1 Cyp51B1 0.0201 0.1355 0.4677
Echinococcus granulosus hyperpolarization activated cyclic 0.0021 0.0033 0.0033
Echinococcus granulosus lysine specific demethylase 5A 0.0096 0.0583 0.0583
Loa Loa (eye worm) phosphatidylinositol 3 0.0036 0.0149 0.0243
Loa Loa (eye worm) hypothetical protein 0.0054 0.0278 0.0453
Trypanosoma cruzi Present in the outer mitochondrial membrane proteome 4 0.0034 0.0129 0.0123
Echinococcus multilocularis neuropeptide Y receptor 0.0054 0.0278 0.0278
Trypanosoma brucei beta-ketoacyl-ACP reductase 2 0.0019 0.0025 0.0007
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0066 0.0368 0.0363
Echinococcus multilocularis sodium:chloride dependent neurotransmitter 0.0025 0.0064 0.0064
Trypanosoma brucei 3-ketoacyl-CoA reductase, putative 0.0019 0.0025 0.0007
Loa Loa (eye worm) hypothetical protein 0.0054 0.0278 0.0453
Entamoeba histolytica short chain dehydrogenase family protein 0.0019 0.0025 0.0036
Schistosoma mansoni amine GPCR 0.0054 0.0278 0.0274
Entamoeba histolytica Phosphatidylinositol 3- and 4-kinase family 0.0021 0.0033 0.0055
Loa Loa (eye worm) hypothetical protein 0.0054 0.0278 0.0453
Plasmodium vivax JmjC domain containing protein 0.0025 0.007 0.0144
Plasmodium falciparum glutathione reductase 0.0409 0.2878 0.6972
Trichomonas vaginalis phosphofructokinase, putative 0.003 0.01 0.0128
Mycobacterium tuberculosis POSSIBLE PARA-NITROBENZYL ESTERASE (FRAGMENT) 0.0083 0.049 0.0932
Trypanosoma cruzi hypothetical protein, conserved 0.0019 0.0025 0.0015
Schistosoma mansoni lamin 0.0052 0.0267 0.0263
Brugia malayi hypothetical protein 0.0054 0.0278 0.0453
Leishmania major myo-inositol-1(or 4)-monophosphatase 1, putative 0.0147 0.0959 0.0982
Entamoeba histolytica estradiol 17-beta-dehydrogenase, putative 0.0019 0.0025 0.0036
Toxoplasma gondii phosphofructokinase PFKII 0.003 0.01 0.0218
Echinococcus granulosus phosphatidylinositol 3 and 4 kinase 0.0036 0.0149 0.0149
Schistosoma mansoni lipoxygenase 0.0418 0.2944 0.2942
Echinococcus multilocularis oxidoreductase 0.0019 0.0025 0.0025
Schistosoma mansoni oxidoreductase short chain dehydrogenase/reductase family 0.0019 0.0025 0.0021
Loa Loa (eye worm) hypothetical protein 0.0491 0.3476 0.5661
Onchocerca volvulus 0.0083 0.049 0.0686
Schistosoma mansoni carbonyl reductase 0.0019 0.0025 0.0021
Trypanosoma cruzi trypanothione reductase, putative 0.0409 0.2878 0.2968
Schistosoma mansoni dihydrolipoamide dehydrogenase 0.0409 0.2878 0.2875
Entamoeba histolytica estradiol 17-beta-dehydrogenase, putative 0.0019 0.0025 0.0036
Mycobacterium tuberculosis NADPH-dependent mycothiol reductase Mtr 0.0579 0.4123 0.8103
Echinococcus granulosus WW domain containing oxidoreductase 0.0019 0.0025 0.0025
Schistosoma mansoni 3-hydroxyacyl-CoA dehydrogenase 0.018 0.1199 0.1196
Brugia malayi Doublecortin family protein 0.016 0.1055 0.1718
Onchocerca volvulus Dehydrogenase\/reductase SDR family member 13 homolog 0.0019 0.0025 0.0021
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0123 0.078 0.078
Trypanosoma cruzi JmjC domain, hydroxylase, putative 0.0025 0.007 0.0061
Onchocerca volvulus 0.0146 0.0952 0.1345
Mycobacterium ulcerans short-chain dehydrogenase 0.0019 0.0025 0.0025
Mycobacterium ulcerans dehydrogenase 0.0019 0.0025 0.0025
Mycobacterium tuberculosis Probable cytochrome P450 monooxygenase 142 Cyp142 0.0054 0.0279 0.0516
Echinococcus granulosus Dehydrogenase:reductase SDR family 0.0019 0.0025 0.0025
Trypanosoma brucei phosphatidylinositol 3-kinase, putative 0.0036 0.0149 0.0136
Echinococcus multilocularis Aryl hydrocarbon receptor nuclear 0.0025 0.0067 0.0067
Brugia malayi Thioredoxin reductase 0.0579 0.4123 0.6716
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0019 0.0025 0.0025
Mycobacterium ulcerans short-chain dehydrogenase 0.0019 0.0025 0.0025
Leishmania major 3-oxoacyl-(acyl-carrier protein) reductase, putative 0.018 0.1199 0.1231
Echinococcus granulosus serotonin receptor 0.0054 0.0278 0.0278
Trichomonas vaginalis 6-phosphofructokinase, putative 0.003 0.01 0.0128
Trichomonas vaginalis dihydroorotate dehydrogenase, putative 0.0109 0.0678 0.0955
Schistosoma mansoni short chain dehydrogenase 0.0019 0.0025 0.0021
Echinococcus multilocularis potassium voltage gated channel subfamily H 0.005 0.0245 0.0245
Mycobacterium ulcerans aldehyde dehydrogenase 0.0122 0.0774 0.2643
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0586 0.4175 0.5955
Echinococcus multilocularis muscleblind protein 1 0.018 0.1203 0.1203
Echinococcus granulosus death domain containing protein 0.0028 0.0088 0.0088
Schistosoma mansoni hypothetical protein 0.05 0.3544 0.3542
Toxoplasma gondii histone lysine demethylase JMJC1/KDM5D/JARID1D 0.0025 0.007 0.0144
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0019 0.0025 0.0041
Schistosoma mansoni rab6-interacting 0.016 0.1055 0.1051
Trypanosoma cruzi cysteine peptidase, putative 0.0066 0.0368 0.037
Echinococcus multilocularis rhodopsin orphan GPCR 0.0054 0.0278 0.0278
Mycobacterium tuberculosis Cytochrome P450 121 Cyp121 0.0054 0.0279 0.0516
Schistosoma mansoni voltage-gated potassium channel 0.0053 0.027 0.0266
Echinococcus multilocularis dihydrolipoamide dehydrogenase 0.0409 0.2878 0.2878
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0134 0.0865 0.0861
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase domain containing protein 0.0038 0.0164 0.0369
Brugia malayi Muscleblind-like protein 0.018 0.1203 0.196
Loa Loa (eye worm) hypothetical protein 0.0083 0.049 0.0798
Schistosoma mansoni sodium/chloride dependent transporter 0.0146 0.0952 0.0948
Trichomonas vaginalis spcc417.12 protein, putative 0.0083 0.049 0.0686
Echinococcus multilocularis conserved hypothetical protein 0.0667 0.4762 0.4762
Loa Loa (eye worm) hypothetical protein 0.0019 0.0025 0.0041
Brugia malayi Voltage-gated potassium channel, HERG (KCNH2)-related. C. elegans unc-103 ortholog 0.005 0.0245 0.04
Loa Loa (eye worm) hypothetical protein 0.016 0.1055 0.1718
Trichomonas vaginalis PIKK family atypical protein kinase 0.0056 0.0296 0.0408
Trichomonas vaginalis mercuric reductase, putative 0.0409 0.2878 0.41
Echinococcus granulosus lamin dm0 0.0052 0.0267 0.0267
Trichomonas vaginalis estradiol 17 beta-dehydrogenase, putative 0.0019 0.0025 0.0021
Mycobacterium ulcerans cytochrome P450 140A5 Cyp140A5 0.0054 0.0279 0.0913
Loa Loa (eye worm) jmjC domain-containing protein 0.0096 0.0583 0.0949
Schistosoma mansoni steroid dehydrogenase 0.0019 0.0025 0.0021
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0019 0.0025 0.0041
Echinococcus multilocularis sodium channel protein 0.0117 0.0743 0.0743
Brugia malayi jmjC domain containing protein 0.0025 0.007 0.0113
Schistosoma mansoni lamin 0.0052 0.0267 0.0263
Mycobacterium ulcerans aldehyde dehydrogenase 0.0122 0.0774 0.2643
Mycobacterium tuberculosis Probable oxidoreductase 0.0019 0.0025 0.0014
Schistosoma mansoni 6-phosphofructokinase 0.011 0.0685 0.0682
Loa Loa (eye worm) hypothetical protein 0.0031 0.0111 0.0181
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0028 0.0088 0.0143
Leishmania major quinonoid dihydropteridine reductase 0.0019 0.0025 0.0015
Brugia malayi hypothetical protein 0.016 0.1055 0.1718
Brugia malayi gonadotropin-releasing hormone receptor 2 0.0054 0.0278 0.0453
Schistosoma mansoni cyclic-nucleotide-gated cation channel 0.0021 0.0033 0.0029
Loa Loa (eye worm) transcription factor SMAD2 0.0116 0.0736 0.1198
Trichomonas vaginalis PIKK family atypical protein kinase 0.0045 0.0214 0.0292
Echinococcus granulosus serine:threonine protein kinase SMG1 0.0021 0.0033 0.0033
Toxoplasma gondii 6-phosphofructokinase 0.003 0.01 0.0218
Echinococcus multilocularis growth hormone secretagogue receptor type 1 0.0054 0.0278 0.0278
Mycobacterium ulcerans short chain dehydrogenase 0.0019 0.0025 0.0025
Echinococcus granulosus Ataxin 2 N terminaldomain containing protein 0.0033 0.0126 0.0126
Echinococcus multilocularis fmrfamide receptor 0.0054 0.0278 0.0278
Leishmania major hypothetical protein, conserved 0.0019 0.0025 0.0015
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.0097 0.059 0.0961
Entamoeba histolytica hypothetical protein, conserved 0.0019 0.0025 0.0036
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0025 0.0064 0.0105
Mycobacterium ulcerans cytochrome P450 143A4 Cyp143A4 0.0054 0.0279 0.0913
Loa Loa (eye worm) cytochrome P450 family protein 0.0093 0.0562 0.0915
Entamoeba histolytica exodeoxyribonuclease III, putative 0.0018 0.0018 0.0018
Schistosoma mansoni ataxia telangiectasia mutated (atm) 0.0038 0.0163 0.0159
Loa Loa (eye worm) hypothetical protein 0.0054 0.0278 0.0453
Mycobacterium ulcerans ketoacyl reductase 0.0019 0.0025 0.0025
Entamoeba histolytica phosphatidylinositol3-kinaseTor2, putative 0.0065 0.0361 0.0841
Echinococcus granulosus steroid dehydrogenase 0.0019 0.0025 0.0025
Brugia malayi jmjC domain containing protein 0.0157 0.1035 0.1687
Echinococcus multilocularis Ankyrin 0.0028 0.009 0.009
Echinococcus multilocularis netrin receptor unc 5 0.0028 0.0088 0.0088
Trichomonas vaginalis PIKK family atypical protein kinase 0.0049 0.0244 0.0335
Plasmodium vivax amine transporter, putative 0.0025 0.0064 0.0132
Brugia malayi Melatonin receptor type 1A 0.0054 0.0278 0.0453
Echinococcus multilocularis estradiol 17 beta dehydrogenase 12 0.0019 0.0025 0.0025
Leishmania major phosphatidylinositol 3-kinase, putative 0.0036 0.0149 0.0144
Echinococcus multilocularis retinol dehydrogenase 13 0.0019 0.0025 0.0025
Loa Loa (eye worm) hypothetical protein 0.032 0.2225 0.3624
Onchocerca volvulus 0.0054 0.0278 0.0383
Loa Loa (eye worm) hypothetical protein 0.0054 0.0278 0.0453
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0054 0.0278 0.0278
Echinococcus granulosus potassium:sodium hyperpolarization activated 0.0021 0.0033 0.0033
Echinococcus multilocularis epidermal retinal dehydrogenase 2 0.0019 0.0025 0.0025
Brugia malayi hypothetical protein 0.0054 0.0278 0.0453
Echinococcus multilocularis neuroligin 0.0083 0.049 0.049
Echinococcus multilocularis lamin dm0 0.0052 0.0267 0.0267
Brugia malayi hypothetical protein 0.0123 0.0782 0.1273
Trichomonas vaginalis conserved hypothetical protein 0.0028 0.0087 0.011
Toxoplasma gondii PHD-finger domain-containing protein 0.003 0.0102 0.0224
Echinococcus granulosus Jumonji AT rich interactive domain 1B 0.0025 0.007 0.007
Toxoplasma gondii non-specific serine/threonine protein kinase 0.0023 0.005 0.0098
Echinococcus granulosus acetylcholinesterase 0.0491 0.3476 0.3476
Echinococcus multilocularis transient receptor potential cation channel 0.0019 0.0025 0.0025
Brugia malayi O-Glycosyl hydrolase family 30 protein 0.0249 0.1709 0.2784
Schistosoma mansoni transient receptor potential channel 4 0.0107 0.0668 0.0665
Schistosoma mansoni hypothetical protein 0.0033 0.0126 0.0122
Loa Loa (eye worm) hypothetical protein 0.0045 0.0211 0.0343
Brugia malayi cytoplasmic intermediate filament protein 0.0028 0.0089 0.0145
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0025 0.0064 0.0105
Echinococcus granulosus rhodopsin orphan GPCR 0.0054 0.0278 0.0278
Loa Loa (eye worm) hypothetical protein 0.0054 0.0278 0.0453
Loa Loa (eye worm) jmjC domain-containing protein 0.0062 0.0336 0.0547
Trypanosoma brucei 3-keto-dihydrosphingosine reductase 0.0019 0.0025 0.0007
Trichomonas vaginalis glutamate synthase, putative 0.0109 0.0678 0.0955
Leishmania major quinonoid dihydropteridine reductase 0.0019 0.0025 0.0015
Echinococcus multilocularis microtubule associated protein 2 0.1382 1 1
Treponema pallidum thioredoxin reductase (trxB) 0.0109 0.0678 0.1587
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.005 0.0249 0.0249
Loa Loa (eye worm) hypothetical protein 0.0083 0.049 0.0798
Brugia malayi hypothetical protein 0.0054 0.0278 0.0453
Brugia malayi neuropeptide F receptor 0.0054 0.0278 0.0453
Trichomonas vaginalis phosphofructokinase, putative 0.011 0.0685 0.0965
Loa Loa (eye worm) hypothetical protein 0.0054 0.0278 0.0453
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0066 0.0368 0.0363
Loa Loa (eye worm) hypothetical protein 0.0024 0.0061 0.01
Mycobacterium tuberculosis Probable oxidoreductase 0.0019 0.0025 0.0014
Trypanosoma brucei target of rapamycin kinase 3, putative 0.0056 0.0296 0.0288
Echinococcus granulosus muscleblind protein 0.018 0.1203 0.1203
Mycobacterium tuberculosis Probable NADPH:adrenodoxin oxidoreductase FprB (adrenodoxin reductase) (AR) (ferredoxin-NADP(+) reductase) 0.0109 0.0678 0.1303
Leishmania major hypothetical protein, conserved 0.0109 0.0678 0.0691
Echinococcus multilocularis neuropeptide s receptor 0.0054 0.0278 0.0278
Mycobacterium ulcerans cytochrome P450 187A5 Cyp187A5 0.0054 0.0279 0.0913
Trichomonas vaginalis conserved hypothetical protein 0.0039 0.0171 0.023
Loa Loa (eye worm) hypothetical protein 0.0054 0.0278 0.0453
Mycobacterium ulcerans NADPH:adrenodoxin oxidoreductase FprB 0.0109 0.0678 0.2308
Echinococcus granulosus mitogen activated protein kinase 3 0.0102 0.063 0.063
Mycobacterium ulcerans short chain dehydrogenase 0.0019 0.0025 0.0025
Brugia malayi Carboxylesterase family protein 0.0083 0.049 0.0798
Trichomonas vaginalis PIKK family atypical protein kinase 0.0054 0.0279 0.0384
Schistosoma mansoni ubiquitin-specific peptidase 8 (C19 family) 0.0038 0.0164 0.016
Onchocerca volvulus Dehydrogenase\/reductase SDR family member 1 homolog 0.0019 0.0025 0.0021
Trypanosoma brucei inositol-1(or 4)-monophosphatase 1, putative 0.0147 0.0959 0.0975
Plasmodium vivax ataxin-2 like protein, putative 0.0074 0.0424 0.1006
Loa Loa (eye worm) hypothetical protein 0.0491 0.3476 0.5661
Trichomonas vaginalis short-chain dehydrogenase, putative 0.0019 0.0025 0.0021
Toxoplasma gondii FATC domain-containing protein 0.0038 0.0163 0.037
Echinococcus multilocularis aldehyde dehydrogenase, mitochondrial 0.0122 0.0774 0.0774

Activities

Activity type Activity value Assay description Source Reference
Potency (functional) = 3.5481 um PUBCHEM_BIOASSAY: qHTS Assay for the Inhibitors of Schistosoma Mansoni Peroxiredoxins. (Class of assay: confirmatory) [Related pubchem assays: 1011 (Confirmation Concentration-Response Assay for Inhibitors of the Schistosoma mansoni Redox Cascade ), 448 (Schistosoma Mansoni Peroxiredoxins (Prx2) and thioredoxin glutathione reductase (TGR) coupled assay)] ChEMBL. No reference
Potency (binding) 3.5481 uM PubChem BioAssay. qHTS Assay for Inhibitors of MBNL1-poly(CUG) RNA binding. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) 11.5821 uM PUBCHEM_BIOASSAY: qHTS screen for small molecules that inhibit ELG1-dependent DNA repair in human embryonic kidney (HEK293T) cells expressing luciferase-tagged ELG1. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID493107, AID493125] ChEMBL. No reference
Potency (functional) = 15.8489 um PUBCHEM_BIOASSAY: qHTS Assay for Identifying a Potential Treatment of Ataxia-Telangiectasia. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) 20.7865 uM PUBCHEM_BIOASSAY: Primary qHTS for delayed death inhibitors of the malarial parasite plastid, 96 hour incubation. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID488745, AID488752, AID488774, AID504848, AID504850] ChEMBL. No reference
Potency (functional) = 25.1189 um PUBCHEM_BIOASSAY: qHTS Assay for Inhibitors of the ERK Signaling Pathway using a Homogeneous Screening Assay. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) = 44.6684 um PUBCHEM_BIOASSAY: qHTS Assay for Inhibitors of Aldehyde Dehydrogenase 1 (ALDH1A1). (Class of assay: confirmatory) [Related pubchem assays: 1030 (qHTS Validation Assay for Inhibitors of aldehyde dehydrogenase 1 (ALDH1A1))] ChEMBL. No reference
Potency (functional) 50.1187 uM PubChem BioAssay. qHTS for Agonist of gsp, the Etiologic Mutation Responsible for Fibrous Dysplasia/McCune-Albright Syndrome: qHTS. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) 89.1251 uM PUBCHEM_BIOASSAY: Inhibitors of Regulator of G Protein Signaling (RGS) 4: qHTS. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID504856] ChEMBL. No reference

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

Bibliographic References

No literature references available for this target.

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