Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Mycobacterium leprae | conserved hypothetical protein | 0.0072 | 0.0777 | 1 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0072 | 0.0777 | 0.1627 |
Echinococcus multilocularis | inositol monophosphatase 1 | 0.0036 | 0.0223 | 0.0194 |
Echinococcus multilocularis | aldehyde dehydrogenase, mitochondrial | 0.0059 | 0.0573 | 0.0545 |
Loa Loa (eye worm) | LGC-31 protein | 0.0028 | 0.0104 | 0.0117 |
Trypanosoma cruzi | DNA polymerase beta thumb, putative | 0.0044 | 0.0339 | 0.0606 |
Brugia malayi | RNA binding protein | 0.019 | 0.2562 | 1 |
Schistosoma mansoni | hypothetical protein | 0.0031 | 0.015 | 0.015 |
Loa Loa (eye worm) | nucleolar RNA-associated protein alpha | 0.0608 | 0.8884 | 1 |
Trypanosoma cruzi | mitochondrial DNA polymerase beta, putative | 0.031 | 0.437 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0028 | 0.0104 | 0.0117 |
Schistosoma mansoni | ran | 0.0042 | 0.0314 | 0.0314 |
Loa Loa (eye worm) | hypothetical protein | 0.0028 | 0.0104 | 0.0117 |
Plasmodium falciparum | GTP-binding nuclear protein RAN/TC4 | 0.0042 | 0.0314 | 0.5081 |
Brugia malayi | calcium-independent alpha-latrotoxin receptor 2, putative | 0.0031 | 0.015 | 0.0333 |
Mycobacterium tuberculosis | Conserved protein | 0.0072 | 0.0777 | 0.0936 |
Trichomonas vaginalis | esterase, putative | 0.0072 | 0.0777 | 1 |
Mycobacterium ulcerans | hypothetical protein | 0.0072 | 0.0777 | 0.2876 |
Echinococcus multilocularis | diuretic hormone 44 receptor GPRdih2 | 0.0031 | 0.015 | 0.012 |
Toxoplasma gondii | ABC1 family protein | 0.0072 | 0.0777 | 1 |
Leishmania major | mitochondrial DNA polymerase beta | 0.031 | 0.437 | 1 |
Brugia malayi | GTP-binding nuclear protein RAN/TC4 | 0.0042 | 0.0314 | 0.0992 |
Brugia malayi | Hypothetical glycine receptor like protein T20B12.9 in chromosome III | 0.0028 | 0.0104 | 0.0149 |
Echinococcus granulosus | suppression of tumorigenicity 18 protein | 0.0054 | 0.0499 | 0.0471 |
Echinococcus granulosus | cadherin EGF LAG seven pass G type receptor | 0.0031 | 0.015 | 0.012 |
Loa Loa (eye worm) | hypothetical protein | 0.0028 | 0.0104 | 0.0117 |
Brugia malayi | Inositol-1 | 0.0036 | 0.0223 | 0.0627 |
Echinococcus granulosus | lamin dm0 | 0.0026 | 0.0076 | 0.0047 |
Loa Loa (eye worm) | latrophilin receptor protein 2 | 0.0031 | 0.015 | 0.0168 |
Echinococcus multilocularis | Cys loop ligand gated ion channel subunit | 0.0028 | 0.0104 | 0.0074 |
Loa Loa (eye worm) | hypothetical protein | 0.0164 | 0.2164 | 0.2436 |
Schistosoma mansoni | tar DNA-binding protein | 0.019 | 0.2562 | 0.2562 |
Schistosoma mansoni | nAChR subunit | 0.0028 | 0.0104 | 0.0104 |
Echinococcus granulosus | nicotinic acetylcholine receptor subunit alpha 8 | 0.0028 | 0.0104 | 0.0074 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0039 | 0.0277 | 0.0461 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0072 | 0.0777 | 0.1627 |
Echinococcus granulosus | lysosomal alpha glucosidase | 0.0178 | 0.2372 | 0.2349 |
Schistosoma mansoni | tar DNA-binding protein | 0.019 | 0.2562 | 0.2562 |
Schistosoma mansoni | scm-relatedprotein containing 4 mbt domains (sfmbt) | 0.0048 | 0.0399 | 0.0399 |
Schistosoma mansoni | aldehyde dehydrogenase | 0.0059 | 0.0573 | 0.0573 |
Brugia malayi | Bromodomain containing protein | 0.0039 | 0.0274 | 0.0833 |
Onchocerca volvulus | 0.0072 | 0.0777 | 0.604 | |
Mycobacterium tuberculosis | Conserved protein | 0.0072 | 0.0777 | 0.0936 |
Loa Loa (eye worm) | hypothetical protein | 0.0031 | 0.015 | 0.0168 |
Brugia malayi | C2-HC type zinc finger protein C.e-MyT1 | 0.0054 | 0.0499 | 0.1733 |
Schistosoma mansoni | hypothetical protein | 0.0608 | 0.8884 | 0.8884 |
Loa Loa (eye worm) | nicotinic acetylcholine receptor alpha subunit | 0.0028 | 0.0104 | 0.0117 |
Echinococcus granulosus | chromobox protein 1 | 0.0069 | 0.0721 | 0.0693 |
Loa Loa (eye worm) | pigment dispersing factor receptor c | 0.0098 | 0.1165 | 0.1312 |
Schistosoma mansoni | nAChR subunit (ShAR1-beta2-like) | 0.0028 | 0.0104 | 0.0104 |
Mycobacterium ulcerans | hypothetical protein | 0.0163 | 0.215 | 1 |
Echinococcus granulosus | glycine receptor subunit alpha 1 | 0.0028 | 0.0104 | 0.0074 |
Schistosoma mansoni | alpha glucosidase | 0.0039 | 0.0277 | 0.0277 |
Loa Loa (eye worm) | hypothetical protein | 0.0067 | 0.0695 | 0.0782 |
Schistosoma mansoni | family S12 unassigned peptidase (S12 family) | 0.0072 | 0.0777 | 0.0777 |
Schistosoma mansoni | tar DNA-binding protein | 0.019 | 0.2562 | 0.2562 |
Trypanosoma brucei | mitochondrial DNA polymerase beta | 0.031 | 0.437 | 1 |
Echinococcus multilocularis | glycine receptor subunit alpha 1 | 0.0028 | 0.0104 | 0.0074 |
Echinococcus granulosus | endonuclease exonuclease phosphatase | 0.0191 | 0.2579 | 0.2557 |
Onchocerca volvulus | Putative nachr subunit | 0.0028 | 0.0104 | 0.0235 |
Trypanosoma cruzi | mitochondrial DNA polymerase beta, putative | 0.031 | 0.437 | 1 |
Schistosoma mansoni | hypothetical protein | 0.0681 | 1 | 1 |
Onchocerca volvulus | 0.0072 | 0.0777 | 0.604 | |
Brugia malayi | RNA recognition motif domain containing protein | 0.019 | 0.2562 | 1 |
Trichomonas vaginalis | inositol monophosphatase, putative | 0.0036 | 0.0223 | 0.1903 |
Echinococcus granulosus | beta LACTamase domain containing family member | 0.0072 | 0.0777 | 0.075 |
Brugia malayi | Glycosyl hydrolases family 31 protein | 0.0178 | 0.2372 | 0.9239 |
Trichomonas vaginalis | chromobox protein, putative | 0.0069 | 0.0721 | 0.9174 |
Onchocerca volvulus | 0.0103 | 0.1237 | 1 | |
Leishmania major | myo-inositol-1(or 4)-monophosphatase 1, putative | 0.0036 | 0.0223 | 0.0336 |
Loa Loa (eye worm) | hypothetical protein | 0.0072 | 0.0777 | 0.0875 |
Mycobacterium tuberculosis | Probable esterase LipL | 0.0072 | 0.0777 | 0.0936 |
Onchocerca volvulus | 0.0028 | 0.0104 | 0.0235 | |
Trypanosoma brucei | hypothetical protein, conserved | 0.0072 | 0.0777 | 0.1627 |
Trypanosoma cruzi | GTP-binding nuclear protein rtb2, putative | 0.0042 | 0.0314 | 0.0548 |
Loa Loa (eye worm) | hypothetical protein | 0.0028 | 0.0104 | 0.0117 |
Onchocerca volvulus | 0.0028 | 0.0104 | 0.0235 | |
Wolbachia endosymbiont of Brugia malayi | fructose-1,6-bisphosphatase | 0.0036 | 0.0223 | 0.5 |
Mycobacterium tuberculosis | Conserved hypothetical protein | 0.0163 | 0.215 | 0.304 |
Echinococcus granulosus | glycine receptor subunit alpha 1 | 0.0028 | 0.0104 | 0.0074 |
Mycobacterium ulcerans | esterase/lipase LipP | 0.0072 | 0.0777 | 0.2876 |
Brugia malayi | RNA, U transporter 1 | 0.0162 | 0.2131 | 0.8274 |
Echinococcus granulosus | SAM and MBT domain containing protein | 0.0048 | 0.0399 | 0.0371 |
Loa Loa (eye worm) | hypothetical protein | 0.0048 | 0.0399 | 0.045 |
Trichomonas vaginalis | myo inositol monophosphatase, putative | 0.0036 | 0.0223 | 0.1903 |
Trichomonas vaginalis | neutral alpha-glucosidase ab precursor, putative | 0.0039 | 0.0277 | 0.2691 |
Trypanosoma brucei | glucosidase, putative | 0.0039 | 0.0277 | 0.0461 |
Schistosoma mansoni | hypothetical protein | 0.0293 | 0.4119 | 0.4119 |
Brugia malayi | Intermediate filament tail domain containing protein | 0.0026 | 0.0076 | 0.004 |
Loa Loa (eye worm) | hypothetical protein | 0.0028 | 0.0104 | 0.0117 |
Schistosoma mansoni | nAChR subunit | 0.0028 | 0.0104 | 0.0104 |
Trichomonas vaginalis | alpha-glucosidase, putative | 0.0039 | 0.0277 | 0.2691 |
Echinococcus multilocularis | nAChR subunit | 0.0028 | 0.0104 | 0.0074 |
Loa Loa (eye worm) | nicotinic acetylcholine receptor non-alpha subunit | 0.0028 | 0.0104 | 0.0117 |
Onchocerca volvulus | 0.0028 | 0.0104 | 0.0235 | |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0039 | 0.0277 | 0.0461 |
Echinococcus multilocularis | nicotinic acetylcholine receptor subunit alpha 8 | 0.0028 | 0.0104 | 0.0074 |
Echinococcus multilocularis | muscleblind protein | 0.0164 | 0.2164 | 0.2141 |
Loa Loa (eye worm) | hypothetical protein | 0.0028 | 0.0104 | 0.0117 |
Trypanosoma cruzi | GTP-binding nuclear protein rtb2, putative | 0.0042 | 0.0314 | 0.0548 |
Loa Loa (eye worm) | hypothetical protein | 0.0054 | 0.0499 | 0.0562 |
Schistosoma mansoni | aldehyde dehydrogenase | 0.0059 | 0.0573 | 0.0573 |
Mycobacterium tuberculosis | Possible penicillin-binding protein | 0.0463 | 0.6693 | 1 |
Schistosoma mansoni | sex comb on midleg homolog | 0.0048 | 0.0399 | 0.0399 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.009 | 0.1037 | 0.1037 |
Echinococcus multilocularis | glycine receptor subunit beta | 0.0028 | 0.0104 | 0.0074 |
Echinococcus multilocularis | importin subunit beta 1 | 0.0057 | 0.0542 | 0.0514 |
Brugia malayi | Neurotransmitter-gated ion-channel ligand binding domain containing protein | 0.0028 | 0.0104 | 0.0149 |
Brugia malayi | beta-lactamase family protein | 0.0072 | 0.0777 | 0.2848 |
Echinococcus multilocularis | SAM and MBT domain containing protein | 0.0048 | 0.0399 | 0.0371 |
Schistosoma mansoni | importin beta-1 | 0.0057 | 0.0542 | 0.0542 |
Loa Loa (eye worm) | hypothetical protein | 0.0028 | 0.0104 | 0.0117 |
Schistosoma mansoni | inositol monophosphatase | 0.0036 | 0.0223 | 0.0223 |
Loa Loa (eye worm) | hypothetical protein | 0.0028 | 0.0104 | 0.0117 |
Loa Loa (eye worm) | beta-lactamase | 0.0072 | 0.0777 | 0.0875 |
Brugia malayi | excitatory GABA receptor EXP-1A | 0.0028 | 0.0104 | 0.0149 |
Leishmania major | mitochondrial DNA polymerase beta-PAK, putative | 0.0147 | 0.19 | 0.4242 |
Trichomonas vaginalis | neutral alpha-glucosidase ab precursor, putative | 0.0039 | 0.0277 | 0.2691 |
Toxoplasma gondii | inositol(myo)-1(or 4)-monophosphatase 2, putative | 0.0036 | 0.0223 | 0.2062 |
Loa Loa (eye worm) | hypothetical protein | 0.0057 | 0.0542 | 0.061 |
Echinococcus multilocularis | GPCR, family 2 | 0.0031 | 0.015 | 0.012 |
Schistosoma mansoni | tar DNA-binding protein | 0.019 | 0.2562 | 0.2562 |
Schistosoma mansoni | nAChR subunit | 0.0028 | 0.0104 | 0.0104 |
Loa Loa (eye worm) | hypothetical protein | 0.0028 | 0.0104 | 0.0117 |
Onchocerca volvulus | Polycomb protein Sfmbt homolog | 0.0048 | 0.0399 | 0.2784 |
Brugia malayi | Neurotransmitter-gated ion-channel transmembrane region family protein | 0.0028 | 0.0104 | 0.0149 |
Brugia malayi | TAR-binding protein | 0.019 | 0.2562 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0072 | 0.0777 | 0.0875 |
Schistosoma mansoni | nAChR subunit | 0.0028 | 0.0104 | 0.0104 |
Echinococcus multilocularis | nicotinic acetylcholine receptor beta 1 subunit | 0.0028 | 0.0104 | 0.0074 |
Echinococcus multilocularis | histone acetyltransferase MYST2 | 0.0054 | 0.0499 | 0.0471 |
Brugia malayi | hypothetical protein | 0.0026 | 0.0079 | 0.005 |
Echinococcus multilocularis | nicotinic acetylcholine receptor a11 subunit | 0.0028 | 0.0104 | 0.0074 |
Mycobacterium tuberculosis | Probable hydrolase | 0.0072 | 0.0777 | 0.0936 |
Brugia malayi | beta-lactamase | 0.0072 | 0.0777 | 0.2848 |
Brugia malayi | acetylcholine receptor protein, alpha-like chain, putative | 0.0028 | 0.0104 | 0.0149 |
Echinococcus multilocularis | nicotinic acetylcholine receptor alpha subunit | 0.0028 | 0.0104 | 0.0074 |
Loa Loa (eye worm) | hypothetical protein | 0.0072 | 0.0777 | 0.0875 |
Trichomonas vaginalis | D-aminoacylase, putative | 0.0072 | 0.0777 | 1 |
Mycobacterium tuberculosis | Possible conserved lipoprotein LpqK | 0.0072 | 0.0777 | 0.0936 |
Mycobacterium tuberculosis | Probable lipase LipE | 0.0072 | 0.0777 | 0.0936 |
Onchocerca volvulus | 0.0072 | 0.0777 | 0.604 | |
Loa Loa (eye worm) | hypothetical protein | 0.0028 | 0.0104 | 0.0117 |
Onchocerca volvulus | 0.0028 | 0.0104 | 0.0235 | |
Loa Loa (eye worm) | hypothetical protein | 0.0026 | 0.0069 | 0.0078 |
Brugia malayi | beta-lactamase family protein | 0.0072 | 0.0777 | 0.2848 |
Schistosoma mansoni | intermediate filament proteins | 0.0026 | 0.0076 | 0.0076 |
Trypanosoma cruzi | importin beta-1 subunit, putative | 0.0046 | 0.0379 | 0.0698 |
Echinococcus granulosus | Cys loop ligand gated ion channel subunit | 0.0028 | 0.0104 | 0.0074 |
Toxoplasma gondii | GTP-binding nuclear protein ran/tc4 | 0.0042 | 0.0314 | 0.3367 |
Entamoeba histolytica | Ran family GTPase | 0.0042 | 0.0314 | 0.5852 |
Echinococcus multilocularis | geminin | 0.0681 | 1 | 1 |
Trichomonas vaginalis | alpha-glucosidase, putative | 0.0039 | 0.0277 | 0.2691 |
Trypanosoma brucei | mitochondrial DNA polymerase beta-PAK | 0.0147 | 0.19 | 0.4242 |
Echinococcus granulosus | bromodomain adjacent to zinc finger domain | 0.0061 | 0.0607 | 0.0579 |
Loa Loa (eye worm) | hypothetical protein | 0.0028 | 0.0104 | 0.0117 |
Loa Loa (eye worm) | hypothetical protein | 0.0072 | 0.0777 | 0.0875 |
Trichomonas vaginalis | Importin beta-1 subunit, putative | 0.0046 | 0.0379 | 0.4177 |
Echinococcus granulosus | intermediate filament protein | 0.0026 | 0.0076 | 0.0047 |
Echinococcus granulosus | acetylcholine receptor subunit beta 1 | 0.0028 | 0.0104 | 0.0074 |
Plasmodium vivax | hypothetical protein, conserved | 0.0072 | 0.0777 | 1 |
Mycobacterium tuberculosis | Probable lipase LipD | 0.0072 | 0.0777 | 0.0936 |
Brugia malayi | nicotinic acetylcholine receptor beta-1 chain precursor | 0.0028 | 0.0104 | 0.0149 |
Schistosoma mansoni | alpha-glucosidase | 0.0153 | 0.1997 | 0.1997 |
Schistosoma mansoni | nAChR subunit (ShAR1-alpha-like) | 0.0028 | 0.0104 | 0.0104 |
Echinococcus multilocularis | muscleblind protein 1 | 0.0164 | 0.2164 | 0.2141 |
Echinococcus granulosus | nicotinic acetylcholine receptor beta 1 subunit | 0.0028 | 0.0104 | 0.0074 |
Loa Loa (eye worm) | ACC-1 protein | 0.0028 | 0.0104 | 0.0117 |
Trichomonas vaginalis | chromobox protein, putative | 0.0069 | 0.0721 | 0.9174 |
Loa Loa (eye worm) | hypothetical protein | 0.0028 | 0.0104 | 0.0117 |
Echinococcus granulosus | GPCR family 2 | 0.0031 | 0.015 | 0.012 |
Trypanosoma cruzi | mitochondrial DNA polymerase beta-PAK, putative | 0.0053 | 0.0483 | 0.0942 |
Loa Loa (eye worm) | ligand-Gated ion Channel family member | 0.0028 | 0.0104 | 0.0117 |
Mycobacterium ulcerans | aldehyde dehydrogenase | 0.0059 | 0.0573 | 0.1816 |
Echinococcus multilocularis | glycine receptor subunit alpha 1 | 0.0028 | 0.0104 | 0.0074 |
Loa Loa (eye worm) | excitatory GABA receptor EXP-1A | 0.0028 | 0.0104 | 0.0117 |
Trypanosoma brucei | importin beta-1 subunit, putative | 0.0057 | 0.0542 | 0.1078 |
Loa Loa (eye worm) | glycosyl hydrolase family 31 protein | 0.0178 | 0.2372 | 0.267 |
Loa Loa (eye worm) | acetylcholine receptor alpha subunit | 0.0028 | 0.0104 | 0.0117 |
Schistosoma mansoni | ran | 0.0042 | 0.0314 | 0.0314 |
Schistosoma mansoni | nAChR subunit | 0.0028 | 0.0104 | 0.0104 |
Loa Loa (eye worm) | mbt repeat family protein | 0.0048 | 0.0399 | 0.045 |
Schistosoma mansoni | bromodomain containing protein | 0.0065 | 0.0662 | 0.0662 |
Echinococcus granulosus | glycine receptor subunit alpha 1 | 0.0028 | 0.0104 | 0.0074 |
Schistosoma mansoni | family S12 unassigned peptidase (S12 family) | 0.0072 | 0.0777 | 0.0777 |
Brugia malayi | Neurotransmitter-gated ion-channel ligand binding domain containing protein | 0.0028 | 0.0104 | 0.0149 |
Echinococcus granulosus | nAChR subunit | 0.0028 | 0.0104 | 0.0074 |
Brugia malayi | Neurotransmitter-gated ion-channel ligand binding domain containing protein | 0.0028 | 0.0104 | 0.0149 |
Echinococcus multilocularis | bromodomain adjacent to zinc finger domain | 0.0061 | 0.0607 | 0.0579 |
Mycobacterium leprae | Probable lipase LipE | 0.0072 | 0.0777 | 1 |
Echinococcus multilocularis | lamin | 0.0026 | 0.0076 | 0.0047 |
Echinococcus granulosus | GTP binding nuclear protein Ran | 0.0042 | 0.0314 | 0.0285 |
Echinococcus granulosus | snurportin 1 | 0.0608 | 0.8884 | 0.8881 |
Echinococcus multilocularis | snurportin 1 | 0.0608 | 0.8884 | 0.8881 |
Trichomonas vaginalis | alpha-glucosidase, putative | 0.0039 | 0.0277 | 0.2691 |
Schistosoma mansoni | Cys-loop ligand gated ion channel subunit | 0.0028 | 0.0104 | 0.0104 |
Loa Loa (eye worm) | hypothetical protein | 0.0028 | 0.0104 | 0.0117 |
Schistosoma mansoni | nAChR subunit | 0.0028 | 0.0104 | 0.0104 |
Echinococcus multilocularis | polycomb protein SCMH1 | 0.0048 | 0.0399 | 0.0371 |
Leishmania major | importin beta-1 subunit, putative | 0.0046 | 0.0379 | 0.0698 |
Schistosoma mansoni | lamin | 0.0026 | 0.0076 | 0.0076 |
Brugia malayi | acetylcholine receptor, alpha-type subunit unc-38 precursor | 0.0028 | 0.0104 | 0.0149 |
Mycobacterium tuberculosis | Probable esterase/lipase LipP | 0.0072 | 0.0777 | 0.0936 |
Echinococcus multilocularis | neuronal acetylcholine receptor subunit alpha 4 | 0.0028 | 0.0104 | 0.0074 |
Loa Loa (eye worm) | inositol-1 | 0.0036 | 0.0223 | 0.0251 |
Brugia malayi | Latrophilin receptor protein 2 | 0.0031 | 0.015 | 0.0333 |
Brugia malayi | chromobox protein homolog 3 | 0.0039 | 0.0263 | 0.0788 |
Brugia malayi | Bromodomain containing protein | 0.0077 | 0.0844 | 0.3117 |
Schistosoma mansoni | nAChR subunit (ShAR1-beta-like) | 0.0028 | 0.0104 | 0.0104 |
Loa Loa (eye worm) | hypothetical protein | 0.0028 | 0.0104 | 0.0117 |
Loa Loa (eye worm) | RNA recognition domain-containing protein domain-containing protein | 0.019 | 0.2562 | 0.2884 |
Echinococcus multilocularis | glycine receptor subunit alpha 1 | 0.0028 | 0.0104 | 0.0074 |
Brugia malayi | Importin beta-1 subunit | 0.0057 | 0.0542 | 0.1905 |
Loa Loa (eye worm) | hypothetical protein | 0.003 | 0.0137 | 0.0154 |
Echinococcus multilocularis | suppression of tumorigenicity 18 protein | 0.0054 | 0.0499 | 0.0471 |
Loa Loa (eye worm) | hypothetical protein | 0.0073 | 0.0778 | 0.0876 |
Schistosoma mansoni | chromobox protein | 0.0069 | 0.0721 | 0.0721 |
Echinococcus granulosus | diuretic hormone 44 receptor GPRdih2 | 0.0031 | 0.015 | 0.012 |
Brugia malayi | Heterochromatin protein 1 | 0.0069 | 0.0721 | 0.2622 |
Echinococcus multilocularis | acetylcholine receptor subunit beta 1 | 0.0028 | 0.0104 | 0.0074 |
Brugia malayi | latrophilin 2 splice variant baaae | 0.0067 | 0.0695 | 0.2519 |
Onchocerca volvulus | Heterochromatin protein 1 homolog | 0.0041 | 0.0307 | 0.1992 |
Loa Loa (eye worm) | intermediate filament protein | 0.0026 | 0.0076 | 0.0086 |
Echinococcus granulosus | glycine receptor subunit beta | 0.0028 | 0.0104 | 0.0074 |
Onchocerca volvulus | 0.0048 | 0.0399 | 0.2784 | |
Echinococcus granulosus | neuronal acetylcholine receptor subunit alpha 4 | 0.0028 | 0.0104 | 0.0074 |
Leishmania major | alpha glucosidase II subunit, putative | 0.0039 | 0.0277 | 0.0461 |
Loa Loa (eye worm) | hypothetical protein | 0.0039 | 0.0263 | 0.0296 |
Brugia malayi | Neurotransmitter-gated ion-channel ligand binding domain containing protein | 0.0028 | 0.0104 | 0.0149 |
Loa Loa (eye worm) | glycosyl hydrolase family 31 protein | 0.0039 | 0.0277 | 0.0312 |
Giardia lamblia | GTP-binding nuclear protein RAN/TC4 | 0.0042 | 0.0314 | 0.5 |
Brugia malayi | intermediate filament protein | 0.0026 | 0.0076 | 0.004 |
Loa Loa (eye worm) | hypothetical protein | 0.0026 | 0.0076 | 0.0086 |
Toxoplasma gondii | glycosyl hydrolase, family 31 protein | 0.0039 | 0.0277 | 0.2835 |
Brugia malayi | Neurotransmitter-gated ion-channel transmembrane region family protein | 0.0028 | 0.0104 | 0.0149 |
Brugia malayi | Neurotransmitter-gated ion-channel transmembrane region family protein | 0.0028 | 0.0104 | 0.0149 |
Brugia malayi | Cation transporter family protein | 0.0028 | 0.0104 | 0.0149 |
Echinococcus granulosus | muscleblind protein | 0.0164 | 0.2164 | 0.2141 |
Echinococcus multilocularis | lamin dm0 | 0.0026 | 0.0076 | 0.0047 |
Loa Loa (eye worm) | GTP-binding regulatory protein Gs alpha-S chain | 0.009 | 0.1037 | 0.1167 |
Schistosoma mansoni | hypothetical protein | 0.0031 | 0.015 | 0.015 |
Loa Loa (eye worm) | hypothetical protein | 0.0028 | 0.0104 | 0.0117 |
Echinococcus granulosus | polycomb protein SCMH1 | 0.0048 | 0.0399 | 0.0371 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.009 | 0.1037 | 0.101 |
Loa Loa (eye worm) | hypothetical protein | 0.0039 | 0.0275 | 0.031 |
Echinococcus granulosus | importin subunit beta 1 | 0.0057 | 0.0542 | 0.0514 |
Trypanosoma brucei | inositol-1(or 4)-monophosphatase 1, putative | 0.0036 | 0.0223 | 0.0336 |
Echinococcus multilocularis | chromobox protein 1 | 0.0069 | 0.0721 | 0.0693 |
Schistosoma mansoni | hypothetical protein | 0.0067 | 0.0695 | 0.0695 |
Echinococcus granulosus | histone acetyltransferase MYST2 | 0.0054 | 0.0499 | 0.0471 |
Echinococcus multilocularis | lysosomal alpha glucosidase | 0.0178 | 0.2372 | 0.2349 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.009 | 0.1037 | 0.1037 |
Echinococcus granulosus | tar DNA binding protein | 0.019 | 0.2562 | 0.254 |
Trypanosoma cruzi | mitochondrial DNA polymerase beta-PAK, putative | 0.0044 | 0.0339 | 0.0606 |
Trichomonas vaginalis | penicillin-binding protein, putative | 0.0072 | 0.0777 | 1 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.009 | 0.1037 | 0.101 |
Loa Loa (eye worm) | beta-LACTamase domain containing family member | 0.0072 | 0.0777 | 0.0875 |
Trypanosoma cruzi | DNA polymerase beta thumb, putative | 0.0044 | 0.0339 | 0.0606 |
Trypanosoma cruzi | myo-inositol-1(or 4)-monophosphatase 1, putative | 0.0036 | 0.0223 | 0.0336 |
Loa Loa (eye worm) | MBCTL1 | 0.0054 | 0.0499 | 0.0562 |
Trichomonas vaginalis | Importin beta-1 subunit, putative | 0.0046 | 0.0379 | 0.4177 |
Schistosoma mansoni | nAChR subunit | 0.0028 | 0.0104 | 0.0104 |
Loa Loa (eye worm) | RNA binding protein | 0.019 | 0.2562 | 0.2884 |
Mycobacterium tuberculosis | Probable aldehyde dehydrogenase | 0.0059 | 0.0573 | 0.0623 |
Schistosoma mansoni | myelin transcription factor 1 myt1 | 0.0054 | 0.0499 | 0.0499 |
Loa Loa (eye worm) | hypothetical protein | 0.0072 | 0.0777 | 0.0875 |
Toxoplasma gondii | hypothetical protein | 0.005 | 0.0436 | 0.5114 |
Trichomonas vaginalis | alpha-glucosidase, putative | 0.0039 | 0.0277 | 0.2691 |
Echinococcus multilocularis | cadherin EGF LAG seven pass G type receptor | 0.0031 | 0.015 | 0.012 |
Brugia malayi | Glycosyl hydrolases family 31 protein | 0.0039 | 0.0277 | 0.0844 |
Trypanosoma brucei | GTP-binding nuclear protein rtb2, putative | 0.0042 | 0.0314 | 0.0548 |
Brugia malayi | mbt repeat family protein | 0.0048 | 0.0399 | 0.1334 |
Loa Loa (eye worm) | hypothetical protein | 0.0098 | 0.1165 | 0.1312 |
Echinococcus multilocularis | musashi | 0.0026 | 0.0076 | 0.0047 |
Brugia malayi | Neurotransmitter-gated ion-channel ligand binding domain containing protein | 0.0028 | 0.0104 | 0.0149 |
Trichomonas vaginalis | ran, putative | 0.0042 | 0.0314 | 0.3233 |
Onchocerca volvulus | Heterochromatin protein 1 homolog | 0.0039 | 0.0263 | 0.161 |
Trichomonas vaginalis | importin beta-1, putative | 0.0046 | 0.0379 | 0.4177 |
Leishmania major | GTP-binding protein, putative | 0.0042 | 0.0314 | 0.0548 |
Entamoeba histolytica | glycosyl hydrolase, family 31 protein | 0.0039 | 0.0277 | 0.3468 |
Echinococcus granulosus | chromobox protein 1 | 0.0069 | 0.0721 | 0.0693 |
Schistosoma mansoni | sex comb on midleg homolog | 0.0048 | 0.0399 | 0.0399 |
Loa Loa (eye worm) | glutamate-gated chloride channel alpha3A subunit | 0.0028 | 0.0104 | 0.0117 |
Echinococcus multilocularis | lysosomal alpha glucosidase | 0.0178 | 0.2372 | 0.2349 |
Brugia malayi | gamma-aminobutyric-acid receptor beta subunit precursor | 0.0028 | 0.0104 | 0.0149 |
Leishmania major | hypothetical protein, conserved | 0.0072 | 0.0777 | 0.1627 |
Echinococcus multilocularis | chromobox protein 1 | 0.0069 | 0.0721 | 0.0693 |
Brugia malayi | Neurotransmitter-gated ion-channel ligand binding domain containing protein | 0.0028 | 0.0104 | 0.0149 |
Echinococcus granulosus | nicotinic acetylcholine receptor a11 subunit | 0.0028 | 0.0104 | 0.0074 |
Echinococcus granulosus | neutral alpha glucosidase AB | 0.0039 | 0.0277 | 0.0248 |
Trichomonas vaginalis | chromobox protein, putative | 0.0041 | 0.0307 | 0.3137 |
Schistosoma mansoni | hypothetical protein | 0.0031 | 0.015 | 0.015 |
Echinococcus granulosus | nicotinic acetylcholine receptor alpha subunit | 0.0028 | 0.0104 | 0.0074 |
Mycobacterium ulcerans | beta-lactamase | 0.0072 | 0.0777 | 0.2876 |
Brugia malayi | acetylcholine receptor alpha subunit precursor, putative | 0.0028 | 0.0104 | 0.0149 |
Schistosoma mansoni | lamin | 0.0026 | 0.0076 | 0.0076 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.009 | 0.1037 | 0.101 |
Mycobacterium ulcerans | lipase LipD | 0.0072 | 0.0777 | 0.2876 |
Trichomonas vaginalis | D-aminoacylase, putative | 0.0072 | 0.0777 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0044 | 0.0342 | 0.0385 |
Echinococcus granulosus | aldehyde dehydrogenase mitochondrial | 0.0059 | 0.0573 | 0.0545 |
Mycobacterium tuberculosis | Conserved protein | 0.0072 | 0.0777 | 0.0936 |
Plasmodium vivax | GTP-binding nuclear protein RAN/TC4, putative | 0.0042 | 0.0314 | 0.3367 |
Schistosoma mansoni | hypothetical protein | 0.0681 | 1 | 1 |
Mycobacterium ulcerans | aldehyde dehydrogenase | 0.0059 | 0.0573 | 0.1816 |
Trypanosoma cruzi | mitochondrial DNA polymerase beta-PAK, putative | 0.0147 | 0.19 | 0.4242 |
Schistosoma mansoni | inositol monophosphatase | 0.0036 | 0.0223 | 0.0223 |
Loa Loa (eye worm) | hypothetical protein | 0.0164 | 0.2164 | 0.2436 |
Trypanosoma brucei | importin beta-1 subunit, putative | 0.0057 | 0.0542 | 0.1078 |
Trichomonas vaginalis | penicillin-binding protein, putative | 0.0072 | 0.0777 | 1 |
Toxoplasma gondii | HEAT repeat-containing protein | 0.0057 | 0.0542 | 0.6627 |
Echinococcus multilocularis | neutral alpha glucosidase AB | 0.0039 | 0.0277 | 0.0248 |
Entamoeba histolytica | hypothetical protein | 0.0046 | 0.0379 | 1 |
Echinococcus granulosus | glycine receptor subunit beta | 0.0028 | 0.0104 | 0.0074 |
Loa Loa (eye worm) | heterochromatin protein 1 | 0.0069 | 0.0721 | 0.0811 |
Trypanosoma cruzi | myo-inositol-1(or 4)-monophosphatase 1, putative | 0.0036 | 0.0223 | 0.0336 |
Loa Loa (eye worm) | hypothetical protein | 0.0072 | 0.0777 | 0.0875 |
Trichomonas vaginalis | alpha-glucosidase, putative | 0.0039 | 0.0277 | 0.2691 |
Echinococcus granulosus | nicotinic acetylcholine receptor subunit type | 0.0028 | 0.0104 | 0.0074 |
Loa Loa (eye worm) | ACC-1 protein | 0.0028 | 0.0104 | 0.0117 |
Loa Loa (eye worm) | hypothetical protein | 0.0028 | 0.0104 | 0.0117 |
Echinococcus multilocularis | GTP binding nuclear protein Ran | 0.0042 | 0.0314 | 0.0285 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0039 | 0.0263 | 0.2489 |
Brugia malayi | Cation transporter family protein | 0.0028 | 0.0104 | 0.0149 |
Echinococcus multilocularis | bromodomain adjacent to zinc finger domain | 0.0037 | 0.0238 | 0.0209 |
Trypanosoma brucei | DNA polymerase beta thumb, putative | 0.0044 | 0.0339 | 0.0606 |
Trichomonas vaginalis | D-aminoacylase, putative | 0.0072 | 0.0777 | 1 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.009 | 0.1037 | 0.1037 |
Echinococcus multilocularis | beta LACTamase domain containing family member | 0.0072 | 0.0777 | 0.075 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0039 | 0.0263 | 0.2489 |
Brugia malayi | nicotinic acetylcholine receptor alpha subunit, putative | 0.0028 | 0.0104 | 0.0149 |
Onchocerca volvulus | 0.003 | 0.0137 | 0.0523 | |
Onchocerca volvulus | 0.0028 | 0.0104 | 0.0235 | |
Schistosoma mansoni | tar DNA-binding protein | 0.019 | 0.2562 | 0.2562 |
Loa Loa (eye worm) | hypothetical protein | 0.0028 | 0.0104 | 0.0117 |
Leishmania major | aldehyde dehydrogenase, mitochondrial precursor | 0.0059 | 0.0573 | 0.1151 |
Brugia malayi | Cation transporter family protein | 0.0028 | 0.0104 | 0.0149 |
Brugia malayi | Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative | 0.0072 | 0.0777 | 0.2848 |
Schistosoma mansoni | alpha-glucosidase | 0.0153 | 0.1997 | 0.1997 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.009 | 0.1037 | 0.101 |
Echinococcus granulosus | lamin | 0.0026 | 0.0076 | 0.0047 |
Loa Loa (eye worm) | hypothetical protein | 0.0028 | 0.0104 | 0.0117 |
Brugia malayi | Calcitonin receptor-like protein seb-1 | 0.0098 | 0.1165 | 0.4403 |
Echinococcus granulosus | bromodomain adjacent to zinc finger domain | 0.0037 | 0.0238 | 0.0209 |
Echinococcus multilocularis | tar DNA binding protein | 0.019 | 0.2562 | 0.254 |
Trichomonas vaginalis | chromobox protein, putative | 0.0041 | 0.0307 | 0.3137 |
Mycobacterium ulcerans | fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE | 0.0072 | 0.0777 | 0.2876 |
Loa Loa (eye worm) | hypothetical protein | 0.0042 | 0.0312 | 0.0351 |
Echinococcus multilocularis | endonuclease exonuclease phosphatase | 0.0191 | 0.2579 | 0.2557 |
Onchocerca volvulus | 0.0028 | 0.0104 | 0.0235 | |
Trichomonas vaginalis | maltase-glucoamylase, putative | 0.0039 | 0.0277 | 0.2691 |
Trichomonas vaginalis | myo inositol monophosphatase, putative | 0.0036 | 0.0223 | 0.1903 |
Schistosoma mansoni | Cys-loop ligand gated ion channel subunit | 0.0028 | 0.0104 | 0.0104 |
Schistosoma mansoni | chromobox protein | 0.0069 | 0.0721 | 0.0721 |
Mycobacterium ulcerans | aldehyde dehydrogenase | 0.0059 | 0.0573 | 0.1816 |
Mycobacterium tuberculosis | Probable conserved lipoprotein | 0.0072 | 0.0777 | 0.0936 |
Toxoplasma gondii | aldehyde dehydrogenase | 0.0059 | 0.0573 | 0.7074 |
Loa Loa (eye worm) | GTP-binding nuclear protein RAN/TC4 | 0.0042 | 0.0314 | 0.0354 |
Brugia malayi | GTP-binding regulatory protein Gs alpha-S chain, putative | 0.009 | 0.1037 | 0.3888 |
Brugia malayi | mbt repeat family protein | 0.0048 | 0.0399 | 0.1334 |
Schistosoma mansoni | hypothetical protein | 0.0031 | 0.015 | 0.015 |
Brugia malayi | Corticotropin releasing factor receptor 2 precursor, putative | 0.0098 | 0.1165 | 0.4403 |
Schistosoma mansoni | acetyl-CoA C-acetyltransferase | 0.0023 | 0.003 | 0.003 |
Trichomonas vaginalis | sucrase-isomaltase, putative | 0.0039 | 0.0277 | 0.2691 |
Brugia malayi | Muscleblind-like protein | 0.0164 | 0.2164 | 0.8405 |
Plasmodium vivax | importin-beta 2, putative | 0.0057 | 0.0542 | 0.6627 |
Echinococcus granulosus | inositol monophosphatase 1 | 0.0036 | 0.0223 | 0.0194 |
Loa Loa (eye worm) | intermediate filament tail domain-containing protein | 0.0026 | 0.0076 | 0.0086 |
Entamoeba histolytica | glycosyl hydrolase, family 31 protein | 0.0039 | 0.0277 | 0.3468 |
Loa Loa (eye worm) | hypothetical protein | 0.0028 | 0.0104 | 0.0117 |
Plasmodium falciparum | importin beta, putative | 0.0057 | 0.0542 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0026 | 0.0079 | 0.0089 |
Echinococcus multilocularis | glycine receptor subunit beta | 0.0028 | 0.0104 | 0.0074 |
Schistosoma mansoni | Cys-loop ligand gated ion channel subunit | 0.0028 | 0.0104 | 0.0104 |
Loa Loa (eye worm) | TAR-binding protein | 0.019 | 0.2562 | 0.2884 |
Activity type | Activity value | Assay description | Source | Reference |
---|---|---|---|---|
Potency (binding) | = 28.1838 um | PUBCHEM_BIOASSAY: qHTS Assay for Inhibitors of Tyrosyl-DNA Phosphodiesterase (TDP1). (Class of assay: confirmatory) | ChEMBL. | No reference |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.