Detailed information for compound 1285659

Basic information

Technical information
  • TDR Targets ID: 1285659
  • Name: 1-(5,6,7,8,9,10-hexahydrocyclohepta[b]indol-2 -ylsulfonyl)-N-(4-methylphenyl)piperidine-4-c arboxamide
  • MW: 465.608 | Formula: C26H31N3O3S
  • H donors: 2 H acceptors: 3 LogP: 4.66 Rotable bonds: 5
    Rule of 5 violations (Lipinski): 1
  • SMILES: Cc1ccc(cc1)NC(=O)C1CCN(CC1)S(=O)(=O)c1ccc2c(c1)c1CCCCCc1[nH]2
  • InChi: 1S/C26H31N3O3S/c1-18-7-9-20(10-8-18)27-26(30)19-13-15-29(16-14-19)33(31,32)21-11-12-25-23(17-21)22-5-3-2-4-6-24(22)28-25/h7-12,17,19,28H,2-6,13-16H2,1H3,(H,27,30)
  • InChiKey: DBSJPHQQQUUMGJ-UHFFFAOYSA-N  

Network

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Synonyms

  • 1-(5,6,7,8,9,10-hexahydrocyclohepta[b]indol-2-ylsulfonyl)-N-(4-methylphenyl)-4-piperidinecarboxamide
  • 1-(5,6,7,8,9,10-hexahydrocyclohepta[b]indol-2-ylsulfonyl)-N-(4-methylphenyl)isonipecotamide
  • G008-0790
  • NCGC00128168-01

Targets

Known targets for this compound

Species Target name Source Bibliographic reference
Homo sapiens tumor protein p53 Starlite/ChEMBL No references
Homo sapiens microtubule-associated protein tau Starlite/ChEMBL No references
Homo sapiens SMAD family member 2 Starlite/ChEMBL No references
Trypanosoma cruzi cysteine peptidase, putative Starlite/ChEMBL No references
Homo sapiens nuclear factor, erythroid 2-like 2 Starlite/ChEMBL No references

Predicted pathogen targets for this compound

By orthology
Species Potential target Known druggable target/s Ortholog Group
Onchocerca volvulus Get druggable targets OG5_126607 All targets in OG5_126607
Echinococcus granulosus cathepsin l1 Get druggable targets OG5_126607 All targets in OG5_126607
Onchocerca volvulus Get druggable targets OG5_126607 All targets in OG5_126607
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase Get druggable targets OG5_126607 All targets in OG5_126607
Trypanosoma congolense cysteine peptidase, Clan CA, family C1, Cathepsin L-like Get druggable targets OG5_126607 All targets in OG5_126607
Echinococcus multilocularis cathepsin L cysteine protease Get druggable targets OG5_126607 All targets in OG5_126607
Echinococcus multilocularis cysteine protease Get druggable targets OG5_126607 All targets in OG5_126607
Trypanosoma congolense cysteine peptidase, Clan CA, family C1, Cathepsin L-like Get druggable targets OG5_126607 All targets in OG5_126607
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like Get druggable targets OG5_126607 All targets in OG5_126607
Leishmania major cathepsin L-like protease Get druggable targets OG5_126607 All targets in OG5_126607
Brugia malayi Cathepsin L-like precursor Get druggable targets OG5_126607 All targets in OG5_126607
Onchocerca volvulus Get druggable targets OG5_126607 All targets in OG5_126607
Cryptosporidium hominis cryptopain precursor Get druggable targets OG5_126607 All targets in OG5_126607
Leishmania mexicana Get druggable targets OG5_126607 All targets in OG5_126607
Cryptosporidium parvum cryptopain - cysteine proteinase secreted, possible transmembrane domain near N-terminus Get druggable targets OG5_126607 All targets in OG5_126607
Leishmania major cathepsin L-like protease Get druggable targets OG5_126607 All targets in OG5_126607
Trypanosoma congolense cysteine peptidase, Clan CA, family C1, Cathepsin L-like Get druggable targets OG5_126607 All targets in OG5_126607
Loa Loa (eye worm) Papain cysteine protease/cathepsin propeptide inhibitor-containing protein Get druggable targets OG5_126607 All targets in OG5_126607
Echinococcus multilocularis cathepsin l cysteine peptidase Get druggable targets OG5_126607 All targets in OG5_126607
Leishmania mexicana Get druggable targets OG5_126607 All targets in OG5_126607
Plasmodium falciparum cysteine proteinase falcipain 2b Get druggable targets OG5_126607 All targets in OG5_126607
Theileria parva cysteine protease, putative Get druggable targets OG5_126607 All targets in OG5_126607
Leishmania mexicana cathepsin L-like protease, putative Get druggable targets OG5_126607 All targets in OG5_126607
Leishmania infantum cysteine peptidase A (CPA) Get druggable targets OG5_126607 All targets in OG5_126607
Trypanosoma congolense cysteine peptidase, Clan CA, family C1, Cathepsin L-like Get druggable targets OG5_126607 All targets in OG5_126607
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase Get druggable targets OG5_126607 All targets in OG5_126607
Schistosoma japonicum Cathepsin L-like proteinase precursor, putative Get druggable targets OG5_126607 All targets in OG5_126607
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase Get druggable targets OG5_126607 All targets in OG5_126607
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like Get druggable targets OG5_126607 All targets in OG5_126607
Echinococcus granulosus cathepsin L cysteine proteinase Get druggable targets OG5_126607 All targets in OG5_126607
Trypanosoma congolense cysteine peptidase, Clan CA, family C1, Cathepsin L-like Get druggable targets OG5_126607 All targets in OG5_126607
Theileria parva cysteine proteinase, putative Get druggable targets OG5_126607 All targets in OG5_126607
Plasmodium berghei berghepain-2 Get druggable targets OG5_126607 All targets in OG5_126607
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase Get druggable targets OG5_126607 All targets in OG5_126607
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_126607 All targets in OG5_126607
Schistosoma mansoni cathepsin F (C01 family) Get druggable targets OG5_126607 All targets in OG5_126607
Leishmania braziliensis cysteine peptidase A (CPA) Get druggable targets OG5_126607 All targets in OG5_126607
Echinococcus granulosus microtubule associated protein 2 Get druggable targets OG5_133504 All targets in OG5_133504
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase Get druggable targets OG5_126607 All targets in OG5_126607
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase Get druggable targets OG5_126607 All targets in OG5_126607
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase Get druggable targets OG5_126607 All targets in OG5_126607
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase Get druggable targets OG5_126607 All targets in OG5_126607
Schistosoma japonicum ko:K01373 cathepsin F [EC3.4.22.41], putative Get druggable targets OG5_126607 All targets in OG5_126607
Brugia malayi Cathepsin L-like precursor Get druggable targets OG5_126607 All targets in OG5_126607
Loa Loa (eye worm) papain family cysteine protease containing protein Get druggable targets OG5_126607 All targets in OG5_126607
Plasmodium knowlesi knowpain-3 Get druggable targets OG5_126607 All targets in OG5_126607
Echinococcus multilocularis cathepsin l cysteine peptidase Get druggable targets OG5_126607 All targets in OG5_126607
Brugia malayi MH2 domain containing protein Get druggable targets OG5_131716 All targets in OG5_131716
Leishmania mexicana Get druggable targets OG5_126607 All targets in OG5_126607
Entamoeba histolytica cysteine protease, putative Get druggable targets OG5_126607 All targets in OG5_126607
Plasmodium knowlesi knowpain-4 Get druggable targets OG5_126607 All targets in OG5_126607
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase Get druggable targets OG5_126607 All targets in OG5_126607
Trypanosoma congolense cysteine peptidase, Clan CA, family C1, Cathepsin L-like Get druggable targets OG5_126607 All targets in OG5_126607
Theileria parva cysteine proteinase, putative Get druggable targets OG5_126607 All targets in OG5_126607
Schistosoma mansoni cathepsin F (C01 family) Get druggable targets OG5_126607 All targets in OG5_126607
Leishmania major cathepsin L-like protease Get druggable targets OG5_126607 All targets in OG5_126607
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_126607 All targets in OG5_126607
Echinococcus multilocularis tumor protein p63 Get druggable targets OG5_140038 All targets in OG5_140038
Echinococcus granulosus cathepsin l cysteine peptidase Get druggable targets OG5_126607 All targets in OG5_126607
Brugia malayi Cathepsin L-like precursor Get druggable targets OG5_126607 All targets in OG5_126607
Entamoeba histolytica cysteine proteinase, putative Get druggable targets OG5_126607 All targets in OG5_126607
Onchocerca volvulus Get druggable targets OG5_126607 All targets in OG5_126607
Echinococcus multilocularis cysteine protease Get druggable targets OG5_126607 All targets in OG5_126607
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase Get druggable targets OG5_126607 All targets in OG5_126607
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase Get druggable targets OG5_126607 All targets in OG5_126607
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase Get druggable targets OG5_126607 All targets in OG5_126607
Trypanosoma brucei gambiense cysteine peptidase precursor,cysteine peptidase, Clan CA, family C1, Cathepsin L-like Get druggable targets OG5_126607 All targets in OG5_126607
Leishmania braziliensis cathepsin L-like protease Get druggable targets OG5_126607 All targets in OG5_126607
Trypanosoma congolense cysteine peptidase, Clan CA, family C1, Cathepsin L-like Get druggable targets OG5_126607 All targets in OG5_126607
Trypanosoma congolense cysteine peptidase, Clan CA, family C1, Cathepsin L-like Get druggable targets OG5_126607 All targets in OG5_126607
Loa Loa (eye worm) MH2 domain-containing protein Get druggable targets OG5_131716 All targets in OG5_131716
Neospora caninum Cathepsin L, related Get druggable targets OG5_126607 All targets in OG5_126607
Echinococcus multilocularis microtubule associated protein 2 Get druggable targets OG5_133504 All targets in OG5_133504
Brugia malayi Cathepsin L-like precursor Get druggable targets OG5_126607 All targets in OG5_126607
Onchocerca volvulus Cathepsin L homolog Get druggable targets OG5_126607 All targets in OG5_126607
Trypanosoma cruzi cysteine peptidase, clan CA, family C1, cathepsin L-like, putative Get druggable targets OG5_126607 All targets in OG5_126607
Loa Loa (eye worm) ctsf protein Get druggable targets OG5_126607 All targets in OG5_126607
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like Get druggable targets OG5_126607 All targets in OG5_126607
Trypanosoma cruzi cysteine peptidase, putative Get druggable targets OG5_126607 All targets in OG5_126607
Brugia malayi Cathepsin L-like precursor Get druggable targets OG5_126607 All targets in OG5_126607
Schistosoma mansoni cathepsin F (C01 family) Get druggable targets OG5_126607 All targets in OG5_126607
Brugia malayi Cathepsin L-like precursor Get druggable targets OG5_126607 All targets in OG5_126607
Leishmania major cathepsin L-like protease Get druggable targets OG5_126607 All targets in OG5_126607
Leishmania mexicana cysteine peptidase A (CBA) Get druggable targets OG5_126607 All targets in OG5_126607
Trypanosoma brucei gambiense cysteine peptidase precursor,cysteine peptidase, Clan CA, family C1, Cathepsin L-like Get druggable targets OG5_126607 All targets in OG5_126607
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase Get druggable targets OG5_126607 All targets in OG5_126607
Trypanosoma congolense cysteine peptidase, Clan CA, family C1, Cathepsin L-like Get druggable targets OG5_126607 All targets in OG5_126607
Onchocerca volvulus Cathepsin F homolog Get druggable targets OG5_126607 All targets in OG5_126607
Toxoplasma gondii cathepsin CPL Get druggable targets OG5_126607 All targets in OG5_126607
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase Get druggable targets OG5_126607 All targets in OG5_126607
Schistosoma mansoni microtubule-associated protein tau Get druggable targets OG5_133504 All targets in OG5_133504
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like Get druggable targets OG5_126607 All targets in OG5_126607
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like Get druggable targets OG5_126607 All targets in OG5_126607
Loa Loa (eye worm) transcription factor SMAD2 Get druggable targets OG5_131716 All targets in OG5_131716
Trypanosoma congolense cysteine peptidase, Clan CA, family C1, Cathepsin L-like Get druggable targets OG5_126607 All targets in OG5_126607
Leishmania major cathepsin L-like protease Get druggable targets OG5_126607 All targets in OG5_126607
Trypanosoma brucei gambiense cysteine peptidase precursor,cysteine peptidase, Clan CA, family C1, Cathepsin L-like Get druggable targets OG5_126607 All targets in OG5_126607
Leishmania braziliensis cathepsin L-like protease Get druggable targets OG5_126607 All targets in OG5_126607
Plasmodium vivax vivapain-2 Get druggable targets OG5_126607 All targets in OG5_126607
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like Get druggable targets OG5_126607 All targets in OG5_126607
Echinococcus granulosus cathepsin l1 Get druggable targets OG5_126607 All targets in OG5_126607
Trypanosoma cruzi cruzipain precursor, putative Get druggable targets OG5_126607 All targets in OG5_126607
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase Get druggable targets OG5_126607 All targets in OG5_126607
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase Get druggable targets OG5_126607 All targets in OG5_126607
Plasmodium yoelii berghepain-2 Get druggable targets OG5_126607 All targets in OG5_126607
Brugia malayi cathepsin L-like precursor Get druggable targets OG5_126607 All targets in OG5_126607
Plasmodium falciparum cysteine proteinase falcipain 3 Get druggable targets OG5_126607 All targets in OG5_126607
Schistosoma japonicum expressed protein Get druggable targets OG5_126607 All targets in OG5_126607
Onchocerca volvulus Cathepsin L homolog Get druggable targets OG5_126607 All targets in OG5_126607
Echinococcus multilocularis cathepsin L cysteine protease Get druggable targets OG5_126607 All targets in OG5_126607
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase Get druggable targets OG5_126607 All targets in OG5_126607
Trypanosoma congolense cysteine peptidase, Clan CA, family C1, Cathepsin L-like Get druggable targets OG5_126607 All targets in OG5_126607
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like Get druggable targets OG5_126607 All targets in OG5_126607
Trypanosoma cruzi cysteine peptidase, putative Get druggable targets OG5_126607 All targets in OG5_126607
Leishmania mexicana cathepsin L-like protease, putative Get druggable targets OG5_126607 All targets in OG5_126607
Leishmania major cathepsin L-like protease Get druggable targets OG5_126607 All targets in OG5_126607
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase Get druggable targets OG5_126607 All targets in OG5_126607
Plasmodium vivax vivapain-2 Get druggable targets OG5_126607 All targets in OG5_126607
Trypanosoma cruzi cysteine peptidase, putative Get druggable targets OG5_126607 All targets in OG5_126607
Brugia malayi Cathepsin L-like cysteine proteinase Get druggable targets OG5_126607 All targets in OG5_126607
Theileria parva cysteine proteinase, putative Get druggable targets OG5_126607 All targets in OG5_126607
Trypanosoma congolense cysteine peptidase, Clan CA, family C1, Cathepsin L-like Get druggable targets OG5_126607 All targets in OG5_126607
Loa Loa (eye worm) cysteine protease Get druggable targets OG5_126607 All targets in OG5_126607
Brugia malayi Cathepsin L-like precursor Get druggable targets OG5_126607 All targets in OG5_126607
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase Get druggable targets OG5_126607 All targets in OG5_126607
Echinococcus granulosus tumor protein p63 Get druggable targets OG5_140038 All targets in OG5_140038
Trypanosoma congolense cysteine peptidase, Clan CA, family C1, Cathepsin L-like Get druggable targets OG5_126607 All targets in OG5_126607
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like Get druggable targets OG5_126607 All targets in OG5_126607
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase Get druggable targets OG5_126607 All targets in OG5_126607
Theileria parva cysteine protease, putative Get druggable targets OG5_126607 All targets in OG5_126607
Onchocerca volvulus Get druggable targets OG5_126607 All targets in OG5_126607
Leishmania major cysteine peptidase A (CPA) Get druggable targets OG5_126607 All targets in OG5_126607
Trypanosoma congolense cysteine peptidase, Clan CA, family C1, Cathepsin L-like Get druggable targets OG5_126607 All targets in OG5_126607
Trypanosoma congolense cysteine peptidase, Clan CA, family C1, Cathepsin L-like Get druggable targets OG5_126607 All targets in OG5_126607
Theileria parva cysteine proteinase Get druggable targets OG5_126607 All targets in OG5_126607
Trypanosoma congolense cysteine peptidase, Clan CA, family C1, Cathepsin L-like Get druggable targets OG5_126607 All targets in OG5_126607
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like Get druggable targets OG5_126607 All targets in OG5_126607
Plasmodium falciparum cysteine proteinase falcipain 2a Get druggable targets OG5_126607 All targets in OG5_126607
Leishmania mexicana Get druggable targets OG5_126607 All targets in OG5_126607
Leishmania major cathepsin L-like protease Get druggable targets OG5_126607 All targets in OG5_126607
Brugia malayi Papain family cysteine protease containing protein Get druggable targets OG5_126607 All targets in OG5_126607
Leishmania infantum cathepsin L-like protease Get druggable targets OG5_126607 All targets in OG5_126607
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase Get druggable targets OG5_126607 All targets in OG5_126607
Leishmania braziliensis cathepsin L-like protease Get druggable targets OG5_126607 All targets in OG5_126607
Leishmania major cathepsin L-like protease Get druggable targets OG5_126607 All targets in OG5_126607
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase Get druggable targets OG5_126607 All targets in OG5_126607
Trypanosoma congolense cysteine peptidase, Clan CA, family C1, Cathepsin L-like Get druggable targets OG5_126607 All targets in OG5_126607
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_126607 All targets in OG5_126607
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase Get druggable targets OG5_126607 All targets in OG5_126607
Onchocerca volvulus Get druggable targets OG5_126607 All targets in OG5_126607
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase Get druggable targets OG5_126607 All targets in OG5_126607
Onchocerca volvulus Get druggable targets OG5_126607 All targets in OG5_126607
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase Get druggable targets OG5_126607 All targets in OG5_126607
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like Get druggable targets OG5_126607 All targets in OG5_126607
Onchocerca volvulus Get druggable targets OG5_126607 All targets in OG5_126607
Leishmania donovani cysteine peptidase A (CBA) Get druggable targets OG5_126607 All targets in OG5_126607
Trypanosoma cruzi cysteine peptidase, putative Get druggable targets OG5_126607 All targets in OG5_126607
Plasmodium knowlesi knowpain-2 Get druggable targets OG5_126607 All targets in OG5_126607
Entamoeba histolytica cysteine proteinase, putative Get druggable targets OG5_126607 All targets in OG5_126607
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase Get druggable targets OG5_126607 All targets in OG5_126607
Trypanosoma congolense cysteine peptidase, Clan CA, family C1, Cathepsin L-like Get druggable targets OG5_126607 All targets in OG5_126607
Loa Loa (eye worm) fibroinase Get druggable targets OG5_126607 All targets in OG5_126607
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_126607 All targets in OG5_126607
Brugia malayi Cathepsin L-like precursor Get druggable targets OG5_126607 All targets in OG5_126607
Schistosoma japonicum ko:K04380 microtubule-associated protein tau, putative Get druggable targets OG5_133504 All targets in OG5_133504
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase Get druggable targets OG5_126607 All targets in OG5_126607
Theileria parva cysteine protease, putative Get druggable targets OG5_126607 All targets in OG5_126607
Leishmania infantum cathepsin L-like protease Get druggable targets OG5_126607 All targets in OG5_126607
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like Get druggable targets OG5_126607 All targets in OG5_126607
Entamoeba histolytica cysteine proteinase, putative Get druggable targets OG5_126607 All targets in OG5_126607
Leishmania mexicana Get druggable targets OG5_126607 All targets in OG5_126607

By sequence similarity to non orthologous known druggable targets
Species Potential target Known druggable target Length Alignment span Identity
Brugia malayi MH2 domain containing protein SMAD family member 2 467 aa 405 aa 31.6 %

Obtained from network model

Ranking Plot


Putative Targets List


Species Potential target Raw Global Species
Entamoeba histolytica Flap nuclease, putative 0.0028 0.0031 0.0039
Toxoplasma gondii tubulin/FtsZ family, GTPase domain-containing protein 0.0498 0.1426 0.2415
Schistosoma mansoni steroid hormone receptor ad4bp 0.0152 0.04 0.065
Plasmodium falciparum isocitrate dehydrogenase [NADP], mitochondrial 0.0179 0.0481 0.0814
Entamoeba histolytica pyrophosphate-dependent phosphofructokinase 0.0031 0.0041 0.0057
Loa Loa (eye worm) hypothetical protein 0.0175 0.0467 0.0786
Trypanosoma cruzi hypothetical protein, conserved 0.0039 0.0062 0.0106
Onchocerca volvulus TPPP family protein homolog 0.0392 0.1113 0.5167
Schistosoma mansoni smad 0.0041 0.007 0.0115
Echinococcus granulosus histone deacetylase 1 0.0928 0.2702 0.4395
Loa Loa (eye worm) 6-phosphofructokinase 0.0117 0.0294 0.0492
Brugia malayi RNase H family protein 0.0212 0.0578 0.098
Loa Loa (eye worm) tubulin gamma chain 0.1147 0.3352 0.5676
Brugia malayi Cytochrome P450 family protein 0.0079 0.0182 0.0308
Echinococcus multilocularis histone deacetylase 1 0.0928 0.2702 0.2702
Echinococcus granulosus smad 0.0092 0.0222 0.0361
Echinococcus multilocularis thymidylate synthase 0.0115 0.029 0.029
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.002 0.0008 0.0013
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.0152 0.04 0.04
Brugia malayi Isocitrate dehydrogenase 0.0179 0.0481 0.0814
Loa Loa (eye worm) histone deacetylase 3 0.0928 0.2702 0.4574
Leishmania major beta tubulin 0.2007 0.5904 1
Trypanosoma brucei beta tubulin 0.2007 0.5904 1
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 22 0.0028 0.003 0.003
Entamoeba histolytica tubulin alpha chain, putative 0.1526 0.4477 0.7579
Onchocerca volvulus 0.002 0.0008 0.003
Echinococcus multilocularis dna polymerase kappa 0.004 0.0066 0.0066
Mycobacterium tuberculosis Probable ATP-dependent CLP protease proteolytic subunit 2 ClpP2 (endopeptidase CLP 2) 0.0062 0.0132 0.0923
Brugia malayi nuclear receptor NHR-88 0.0152 0.04 0.0677
Trypanosoma cruzi cysteine peptidase, putative 0.0077 0.0177 0.0299
Loa Loa (eye worm) glutathione reductase 0.0051 0.0098 0.0161
Echinococcus multilocularis histone deacetylase 6 0.0409 0.1163 0.1163
Loa Loa (eye worm) hypothetical protein 0.0067 0.0146 0.0242
Schistosoma mansoni histone deacetylase 0.0928 0.2702 0.4395
Leishmania major isocitrate dehydrogenase, putative 0.0022 0.0013 0.0021
Entamoeba histolytica deoxycytidyl transferase, putative 0.004 0.0066 0.0099
Plasmodium vivax thioredoxin reductase, putative 0.0051 0.0098 0.0167
Trichomonas vaginalis phosphofructokinase, putative 0.0117 0.0294 0.0498
Plasmodium falciparum cysteine proteinase falcipain 2b 0.002 0.0008 0.0013
Mycobacterium tuberculosis Probable ATP-dependent CLP protease proteolytic subunit 1 ClpP1 (endopeptidase CLP) 0.0062 0.0132 0.0923
Echinococcus multilocularis muscleblind protein 0.031 0.0869 0.0869
Plasmodium falciparum U4/U6.U5 tri-snRNP-associated protein 2, putative 0.0028 0.003 0.0052
Schistosoma mansoni tubulin subunit beta 0.2007 0.5904 0.9601
Toxoplasma gondii exonuclease III APE 0.0077 0.0176 0.0299
Brugia malayi Calcitonin receptor-like protein seb-1 0.0204 0.0555 0.0939
Brugia malayi TAZ zinc finger family protein 0.0116 0.0293 0.0496
Trichomonas vaginalis conserved hypothetical protein 0.003 0.0036 0.0061
Echinococcus multilocularis microtubule associated protein 2 0.0833 0.2421 0.2421
Brugia malayi Cathepsin L-like precursor 0.002 0.0008 0.0013
Brugia malayi Pao retrotransposon peptidase family protein 0.0018 0.0001 0.0002
Brugia malayi tubulin alpha chain - mouse 0.1526 0.4477 0.7583
Schistosoma mansoni hepatocyte nuclear factor 4-alpha (hnf-4-alpha) 0.0067 0.0146 0.0238
Leishmania major hypothetical protein, conserved 0.0024 0.002 0.0033
Echinococcus multilocularis tubulin alpha 1C chain 0.1526 0.4477 0.4477
Loa Loa (eye worm) hypothetical protein 0.0022 0.0012 0.0014
Leishmania major beta tubulin 0.2007 0.5904 1
Onchocerca volvulus Cathepsin F homolog 0.002 0.0008 0.003
Leishmania major beta tubulin 0.2007 0.5904 1
Schistosoma mansoni tubulin subunit alpha 0.0498 0.1426 0.2319
Brugia malayi Tubulin beta chain 0.0649 0.1874 0.3174
Trypanosoma cruzi cysteine peptidase, putative 0.0077 0.0177 0.0299
Echinococcus granulosus CREB binding protein 0.0075 0.0169 0.0275
Loa Loa (eye worm) hypothetical protein 0.0064 0.0139 0.023
Chlamydia trachomatis fructose-6-phosphate phosphotransferase 0.0031 0.0041 0.1811
Brugia malayi Pao retrotransposon peptidase family protein 0.0018 0.0001 0.0002
Toxoplasma gondii histone deacetylase HDAC5 0.0299 0.0834 0.1413
Loa Loa (eye worm) tubulin alpha 2 0.0379 0.1072 0.1811
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.0056 0.0114 0.0188
Giardia lamblia Endonuclease/Exonuclease/phosphatase 0.0077 0.0176 0.0299
Trichomonas vaginalis phosphofructokinase, putative 0.0031 0.0041 0.007
Onchocerca volvulus Putative hydroxypyruvate isomerase 0.0022 0.0012 0.0049
Onchocerca volvulus 0.0506 0.145 0.6735
Loa Loa (eye worm) beta-tubulin 0.2007 0.5904 1
Schistosoma mansoni CREB-binding protein 2 0.0116 0.0293 0.0476
Loa Loa (eye worm) intermediate filament protein 0.0056 0.0114 0.0188
Trichomonas vaginalis tubulin beta chain, putative 0.1526 0.4477 0.7583
Schistosoma mansoni protein kinase 0.0018 0.0001 0.0002
Schistosoma mansoni Smad4 0.0092 0.0222 0.0361
Trichomonas vaginalis conserved hypothetical protein 0.0042 0.0072 0.0122
Brugia malayi follicle stimulating hormone receptor 0.0254 0.07 0.1186
Schistosoma mansoni DNA polymerase eta 0.004 0.0066 0.0108
Giardia lamblia Reverse transcriptase/endonuclease, putative 0.0018 0.0001 0.0002
Echinococcus granulosus neuropeptide receptor A26 0.05 0.1433 0.233
Loa Loa (eye worm) hypothetical protein 0.014 0.0363 0.0609
Entamoeba histolytica histone deacetylase, putative 0.0928 0.2702 0.457
Mycobacterium ulcerans DNA polymerase IV 0.004 0.0066 0.0464
Mycobacterium tuberculosis Possible cytochrome P450 126 Cyp126 0.0019 0.0003 0.0024
Echinococcus multilocularis cytoplasmic intermediate filament protein 0.0027 0.0028 0.0028
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0019 0.0005 0.0008
Mycobacterium ulcerans cytochrome P450 191A3 Cyp191A3 0.0019 0.0003 0.0024
Trypanosoma brucei beta tubulin 0.2007 0.5904 1
Trichomonas vaginalis histone deacetylase, putative 0.0928 0.2702 0.4577
Chlamydia trachomatis dihydrofolate reductase 0.0047 0.0087 0.3827
Mycobacterium leprae PROBABLE THYMIDYLATE SYNTHASE THYA (TS) (TSASE) 0.0115 0.029 0.2014
Trypanosoma brucei Lanosterol 14-alpha demethylase 0.0019 0.0003 0.0006
Echinococcus multilocularis dna polymerase eta 0.004 0.0066 0.0066
Schistosoma mansoni jumonji/arid domain-containing protein 0.0061 0.0129 0.0209
Mycobacterium ulcerans aldehyde dehydrogenase 0.0062 0.0132 0.0928
Mycobacterium ulcerans beta-lactamase 0.0039 0.0062 0.0438
Trichomonas vaginalis reverse transcriptase [C. elegans], putative 0.0018 0.0001 0.0002
Loa Loa (eye worm) fibroinase 0.002 0.0008 0.0007
Loa Loa (eye worm) hypothetical protein 0.0027 0.0028 0.0042
Trichomonas vaginalis tubulin beta chain, putative 0.1526 0.4477 0.7583
Echinococcus multilocularis cpg binding protein 0.0033 0.0044 0.0044
Trichomonas vaginalis tubulin epsilon chain, putative 0.2007 0.5904 1
Loa Loa (eye worm) CYP4Cod1 0.0028 0.0031 0.0047
Echinococcus granulosus microtubule associated protein 2 0.0833 0.2421 0.3938
Leishmania major beta tubulin 0.2007 0.5904 1
Trypanosoma cruzi Ring finger domain/Zn-finger in ubiquitin-hydrolases and other protein, putative 0.0024 0.002 0.0033
Echinococcus multilocularis tubulin alpha chain 0.1526 0.4477 0.4477
Echinococcus granulosus tubulin alpha chain 0.1526 0.4477 0.728
Loa Loa (eye worm) alpha-tubulin isotype 2 0.1028 0.2998 0.5076
Echinococcus multilocularis neuropeptide s receptor 0.05 0.1433 0.1433
Trypanosoma brucei DNA polymerase IV, putative 0.004 0.0066 0.0112
Loa Loa (eye worm) hypothetical protein 0.0152 0.04 0.0671
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.019 0.0511 0.0861
Trypanosoma brucei DNA polymerase kappa, putative 0.004 0.0066 0.0112
Brugia malayi N-terminal motif family protein 0.0179 0.0479 0.0812
Echinococcus multilocularis RNA directed DNA polymerase (reverse transcriptase) 0.0018 0.0001 0.0001
Trypanosoma cruzi DNA polymerase kappa, putative 0.004 0.0066 0.0112
Mycobacterium tuberculosis Dihydrofolate reductase DfrA (DHFR) (tetrahydrofolate dehydrogenase) 0.0047 0.0087 0.0612
Mycobacterium leprae PROBABLE 6-PHOSPHOFRUCTOKINASE PFKA (PHOSPHOHEXOKINASE) (PHOSPHOFRUCTOKINASE) 0.0117 0.0294 0.2042
Schistosoma mansoni tubulin subunit beta 0.2007 0.5904 0.9601
Leishmania major alpha tubulin 0.1526 0.4477 0.7583
Entamoeba histolytica hypothetical protein 0.0409 0.1161 0.1955
Leishmania major DNA polymerase kappa, putative,DNA polymerase IV, putative 0.004 0.0066 0.0112
Leishmania major alpha tubulin 0.1526 0.4477 0.7583
Schistosoma mansoni RAR-like nuclear receptor 0.0152 0.04 0.065
Mycobacterium ulcerans aldehyde dehydrogenase 0.0062 0.0132 0.0928
Mycobacterium tuberculosis Hypothetical protein 0.0055 0.0111 0.0775
Giardia lamblia Delta tubulin 0.0498 0.1426 0.2415
Mycobacterium ulcerans 3-isopropylmalate dehydrogenase 0.0022 0.0013 0.0088
Loa Loa (eye worm) hypothetical protein 0.0178 0.0477 0.0802
Mycobacterium tuberculosis Probable cytochrome P450 128 Cyp128 0.0019 0.0003 0.0024
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription factor 0.009 0.0215 0.0215
Echinococcus multilocularis Smad4 0.0092 0.0222 0.0222
Mycobacterium tuberculosis Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras 0.0129 0.033 0.2311
Loa Loa (eye worm) hypothetical protein 0.0042 0.0072 0.0116
Brugia malayi hypothetical protein 0.0175 0.0467 0.0792
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.019 0.0511 0.0831
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0068 0.0149 0.0242
Trichomonas vaginalis tubulin beta chain, putative 0.2007 0.5904 1
Trichomonas vaginalis isocitrate dehydrogenase, putative 0.0022 0.0013 0.0021
Toxoplasma gondii histone deacetylase HDAC2 0.0928 0.2702 0.4577
Giardia lamblia Alpha-tubulin 0.1526 0.4477 0.7583
Echinococcus multilocularis cathepsin L cysteine protease 0.002 0.0008 0.0008
Loa Loa (eye worm) hypothetical protein 0.0039 0.0062 0.01
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0077 0.0177 0.0299
Brugia malayi Probable isocitrate dehydrogenase 0.0022 0.0013 0.0021
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0077 0.0177 0.0299
Chlamydia trachomatis ATP-dependent Clp protease proteolytic subunit 0.0094 0.0228 1
Brugia malayi intermediate filament protein 0.0056 0.0114 0.0193
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0179 0.0481 0.0481
Brugia malayi cytoplasmic intermediate filament protein 0.003 0.0037 0.0063
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0077 0.0177 0.0299
Echinococcus multilocularis CREB binding protein 0.0018 0.0001 0.0001
Echinococcus multilocularis tubulin alpha 1C chain 0.1526 0.4477 0.4477
Toxoplasma gondii isocitrate dehydrogenase 0.0179 0.0481 0.0814
Toxoplasma gondii 6-phosphofructokinase 0.0031 0.0041 0.007
Brugia malayi hypothetical protein 0.0178 0.0477 0.0808
Giardia lamblia Beta tubulin 0.2007 0.5904 1
Mycobacterium tuberculosis Probable hydrolase 0.0039 0.0062 0.0438
Entamoeba histolytica phosphofructokinase, putative 0.0117 0.0294 0.0485
Schistosoma mansoni gcn5proteinral control of amino-acid synthesis 5-like 2 gcnl2 0.0307 0.0859 0.1397
Echinococcus multilocularis geminin 0.2089 0.6149 0.6149
Echinococcus granulosus Mitotic checkpoint protein PRCC C terminal 0.0135 0.0349 0.0567
Schistosoma mansoni peptidase Clp (S14 family) 0.0094 0.0228 0.0371
Leishmania major ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative 0.0028 0.003 0.0052
Schistosoma mansoni flap endonuclease-1 0.0025 0.0023 0.0037
Trichomonas vaginalis histone deacetylase, putative 0.0928 0.2702 0.4577
Trichomonas vaginalis phosphofructokinase, putative 0.0117 0.0294 0.0498
Brugia malayi hypoxia-induced factor 1 0.0161 0.0427 0.0724
Loa Loa (eye worm) hypothetical protein 0.0033 0.0045 0.0071
Loa Loa (eye worm) hypothetical protein 0.0067 0.0146 0.0242
Wolbachia endosymbiont of Brugia malayi exonuclease III 0.0077 0.0176 0.1236
Loa Loa (eye worm) heterochromatin protein 1 0.0075 0.017 0.0282
Trypanosoma brucei DNA polymerase kappa, putative 0.0027 0.0029 0.005
Schistosoma mansoni tubulin subunit delta 0.0498 0.1426 0.2319
Leishmania major hypothetical protein, conserved 0.0024 0.002 0.0033
Mycobacterium leprae PROBABLE NADH DEHYDROGENASE NDH 0.0116 0.0291 0.2023
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0152 0.04 0.0677
Echinococcus granulosus RNA directed DNA polymerase 0.0018 0.0001 0.0002
Echinococcus granulosus BRCA1 associated protein 0.0024 0.002 0.0032
Brugia malayi Cytochrome P450 family protein 0.0019 0.0003 0.0006
Brugia malayi phosphofructokinase 0.0117 0.0294 0.0498
Loa Loa (eye worm) hypothetical protein 0.0067 0.0146 0.0242
Trichomonas vaginalis chromobox protein, putative 0.0045 0.0082 0.0138
Brugia malayi Nuclear hormone receptor-like 1 0.0085 0.0201 0.0341
Schistosoma mansoni transcription factor LCR-F1 0.0409 0.1161 0.1888
Trypanosoma cruzi DNA polymerase eta, putative 0.004 0.0066 0.0112
Mycobacterium ulcerans DNA polymerase IV 0.004 0.0066 0.0464
Toxoplasma gondii bifunctional dihydrofolate reductase-thymidylate synthase 0.0162 0.0429 0.0727
Trichomonas vaginalis conserved hypothetical protein 0.0042 0.0072 0.0122
Treponema pallidum ATP-dependent Clp protease proteolytic subunit 0.0094 0.0228 0.16
Echinococcus multilocularis Ataxin 2, N terminal,domain containing protein 0.008 0.0185 0.0185
Loa Loa (eye worm) BEN-1 protein 0.2007 0.5904 1
Echinococcus multilocularis tubulin subunit beta 0.2007 0.5904 0.5904
Leishmania major gamma-tubulin 0.1147 0.3352 0.5678
Trypanosoma brucei beta tubulin 0.2007 0.5904 1
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.0152 0.04 0.065
Leishmania major epsilon tubulin, putative 0.1147 0.3352 0.5678
Entamoeba histolytica exodeoxyribonuclease III, putative 0.0077 0.0176 0.0286
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0061 0.013 0.0211
Loa Loa (eye worm) Smad1 0.0092 0.0222 0.0371
Mycobacterium ulcerans cytochrome P450 143A4 Cyp143A4 0.0019 0.0003 0.0024
Onchocerca volvulus 0.0103 0.0253 0.1169
Echinococcus granulosus Tubulin alpha 1 chain 0.1526 0.4477 0.728
Brugia malayi ecdysteroid receptor 0.0152 0.04 0.0677
Schistosoma mansoni jumonji domain containing protein 0.0059 0.0123 0.0201
Trichomonas vaginalis brca1-associated protein, putative 0.0024 0.002 0.0033
Trypanosoma brucei alpha tubulin 0.1526 0.4477 0.7583
Plasmodium falciparum histone deacetylase, putative 0.0409 0.1163 0.197
Echinococcus granulosus Tubulin beta 2C chain 0.2007 0.5904 0.9601
Echinococcus granulosus mothers against decapentaplegic 5 0.0092 0.0222 0.0361
Leishmania major beta tubulin 0.2007 0.5904 1
Mycobacterium tuberculosis Probable cytochrome P450 144 Cyp144 0.0019 0.0003 0.0024
Echinococcus multilocularis ATP dependent Clp protease proteolytic subunit 0.0094 0.0228 0.0228
Trypanosoma brucei DNA polymerase kappa, putative 0.004 0.0066 0.0112
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0028 0.003 0.0052
Echinococcus granulosus aldehyde dehydrogenase mitochondrial 0.0062 0.0132 0.0215
Schistosoma mansoni cathepsin F (C01 family) 0.002 0.0008 0.0013
Trypanosoma brucei ubiquitin carboxyl-terminal hydrolase, putative 0.0028 0.003 0.0052
Leishmania major beta tubulin 0.2007 0.5904 1
Plasmodium vivax 6-phosphofructokinase, putative 0.0031 0.0041 0.007
Trypanosoma cruzi cytochrome P450, putative 0.0028 0.0031 0.0053
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0152 0.04 0.0677
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0077 0.0177 0.0299
Trypanosoma brucei ubiquitin carboxyl-terminal hydrolase, putative 0.0028 0.003 0.0052
Leishmania major hypothetical protein, conserved 0.0178 0.0477 0.0808
Echinococcus granulosus neuropeptide s receptor 0.05 0.1433 0.233
Schistosoma mansoni alpha tubulin 0.1526 0.4477 0.728
Brugia malayi Intermediate filament tail domain containing protein 0.0056 0.0114 0.0193
Leishmania major DNA polymerase eta, putative 0.004 0.0066 0.0112
Leishmania major cathepsin L-like protease 0.002 0.0008 0.0013
Loa Loa (eye worm) phosphofructokinase 0.0117 0.0294 0.0492
Leishmania major alpha tubulin 0.1526 0.4477 0.7583
Echinococcus granulosus muscleblind protein 0.031 0.0869 0.1413
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.019 0.0511 0.0511
Brugia malayi MH1 domain containing protein 0.0092 0.0222 0.0376
Echinococcus multilocularis isocitrate dehydrogenase (NAD) subunit 0.0022 0.0013 0.0013
Wolbachia endosymbiont of Brugia malayi cell division protein FtsZ 0.0498 0.1426 1
Loa Loa (eye worm) hypothetical protein 0.0115 0.029 0.0485
Mycobacterium ulcerans cytochrome P450 124A1, Cyp124A1 0.0019 0.0003 0.0024
Toxoplasma gondii ATP-dependent Clp endopeptidase, proteolytic subunit ClpP domain-containing protein 0.0094 0.0228 0.0386
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.002 0.0008 0.0013
Trypanosoma cruzi dihydrofolate reductase-thymidylate synthase, putative 0.0055 0.0111 0.0187
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.0152 0.04 0.065
Echinococcus multilocularis tubulin gamma 1 chain 0.1147 0.3352 0.3352
Schistosoma mansoni tubulin subunit alpha 0.1526 0.4477 0.728
Brugia malayi conserved hypotetical protein 0.0067 0.0146 0.0248
Trypanosoma brucei retrotransposon hot spot protein 4 (RHS4), interrupted 0.023 0.0632 0.107
Schistosoma mansoni histone deacetylase 4 5 0.0409 0.1163 0.1891
Schistosoma mansoni family C19 non-peptidase homologue (C19 family) 0.0028 0.003 0.005
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0179 0.0481 0.0481
Loa Loa (eye worm) tubulin beta-4 chain 0.2007 0.5904 1
Schistosoma mansoni tubulin subunit beta 0.0498 0.1426 0.2319
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.002 0.0008 0.0013
Brugia malayi hypothetical protein 0.0085 0.0201 0.0341
Wolbachia endosymbiont of Brugia malayi ribonuclease HI 0.0212 0.0578 0.4055
Toxoplasma gondii ATP-dependent Clp endopeptidase, proteolytic subunit ClpP domain-containing protein 0.0094 0.0228 0.0386
Mycobacterium tuberculosis Probable NADH dehydrogenase Ndh 0.0116 0.0291 0.2042
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.0152 0.04 0.0671
Plasmodium falciparum cysteine proteinase falcipain 3 0.002 0.0008 0.0013
Mycobacterium tuberculosis Probable cytochrome P450 139 Cyp139 0.0019 0.0003 0.0024
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.0152 0.04 0.04
Plasmodium falciparum histone acetyltransferase GCN5 0.0082 0.0192 0.0325
Loa Loa (eye worm) MH1 domain-containing protein 0.0041 0.007 0.0113
Echinococcus granulosus chromobox protein 1 0.0075 0.017 0.0276
Mycobacterium tuberculosis Probable thymidylate synthase ThyA (ts) (TSASE) 0.0115 0.029 0.2033
Loa Loa (eye worm) hypothetical protein 0.0085 0.0201 0.0335
Brugia malayi jmjC domain containing protein 0.0061 0.0129 0.0218
Brugia malayi Pao retrotransposon peptidase family protein 0.0018 0.0001 0.0002
Leishmania major apurinic/apyrimidinic endonuclease-redox protein 0.0077 0.0176 0.0299
Brugia malayi DNA-(Apurinic or apyrimidinic site) lyase 0.0082 0.0192 0.0325
Plasmodium falciparum apurinic/apyrimidinic endonuclease Apn1, putative 0.0082 0.0192 0.0325
Toxoplasma gondii thioredoxin reductase 0.0051 0.0098 0.0167
Echinococcus multilocularis Transcription factor, JmjC domain containing protein 0.0059 0.0123 0.0123
Schistosoma mansoni thyroid hormone receptor 0.0287 0.08 0.1302
Echinococcus multilocularis CREB binding protein 0.0018 0.0001 0.0001
Entamoeba histolytica phosphofructokinase, putative 0.0117 0.0294 0.0485
Trypanosoma cruzi Lanosterol 14-alpha demethylase 0.0019 0.0003 0.0006
Mycobacterium leprae PROBABLE ENDONUCLEASE IV END (ENDODEOXYRIBONUCLEASE IV) (APURINASE) 0.0082 0.0192 0.1324
Echinococcus multilocularis cathepsin L cysteine protease 0.002 0.0008 0.0008
Loa Loa (eye worm) ImpB/MucB/SamB family protein 0.004 0.0066 0.0106
Echinococcus granulosus cathepsin l cysteine peptidase 0.002 0.0008 0.0013
Onchocerca volvulus 0.0056 0.0114 0.0524
Trypanosoma brucei histone deacetylase 2 0.0299 0.0834 0.1413
Trypanosoma brucei SLACS reverse transcriptase, putative 0.0018 0.0001 0.0002
Onchocerca volvulus Uncharacterized RING finger protein homolog 0.0024 0.002 0.0085
Trichomonas vaginalis phosphofructokinase, putative 0.0117 0.0294 0.0498
Brugia malayi MH1 domain containing protein 0.0051 0.01 0.0169
Loa Loa (eye worm) CXXC zinc finger family protein 0.0031 0.0039 0.0061
Mycobacterium tuberculosis Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB 0.0116 0.0291 0.2042
Trypanosoma brucei alpha tubulin 0.1526 0.4477 0.7583
Brugia malayi nuclear hormone receptor 0.0152 0.04 0.0677
Loa Loa (eye worm) acetyltransferase 0.0307 0.0859 0.145
Mycobacterium tuberculosis Probable cytochrome P450 123 Cyp123 0.0019 0.0003 0.0024
Mycobacterium leprae cell division protein FtsZ 0.0498 0.1426 1
Echinococcus granulosus RNA directed DNA polymerase reverse transcriptase 0.0018 0.0001 0.0002
Echinococcus granulosus tubulin alpha 0.1147 0.3352 0.5452
Onchocerca volvulus 0.0039 0.0062 0.0284
Trypanosoma cruzi tubulin delta chain 0.0498 0.1426 0.2415
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0152 0.04 0.0677
Echinococcus granulosus tubulin subunit beta 0.2007 0.5904 0.9601
Echinococcus multilocularis flap endonuclease 1 0.0028 0.0031 0.0031
Schistosoma mansoni nuclear hormone receptor 0.0152 0.04 0.065
Trypanosoma cruzi DNA polymerase kappa, putative 0.004 0.0066 0.0112
Brugia malayi Latrophilin receptor protein 2 0.0065 0.014 0.0237
Loa Loa (eye worm) hypothetical protein 0.0111 0.0276 0.0462
Loa Loa (eye worm) dihydrofolate reductase 0.0047 0.0087 0.0142
Mycobacterium tuberculosis Probable isocitrate dehydrogenase [NADP] Icd1 (oxalosuccinate decarboxylase) (IDH) (NADP+-specific ICDH) (IDP) 0.0179 0.0481 0.337
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0077 0.0177 0.0299
Brugia malayi Pao retrotransposon peptidase family protein 0.0018 0.0001 0.0002
Trichomonas vaginalis tubulin epsilon chain, putative 0.1526 0.4477 0.7583
Echinococcus multilocularis hypothetical protein 0.1526 0.4477 0.4477
Brugia malayi hypothetical protein 0.0409 0.1161 0.1966
Leishmania major cathepsin L-like protease 0.002 0.0008 0.0013
Trypanosoma cruzi cysteine peptidase, putative 0.0077 0.0177 0.0299
Loa Loa (eye worm) cytochrome P450 family protein 0.0028 0.0031 0.0047
Mycobacterium tuberculosis Possible penicillin-binding protein 0.0247 0.068 0.477
Schistosoma mansoni aryl hydrocarbon receptor 0.0053 0.0104 0.017
Onchocerca volvulus Histone deacetylase 10 homolog 0.0299 0.0834 0.3873
Echinococcus multilocularis lamin 0.0056 0.0114 0.0114
Echinococcus granulosus KRAB A domain containing protein 0.0018 0.0001 0.0002
Giardia lamblia Histone acetyltransferase GCN5 0.0082 0.0192 0.0325
Mycobacterium tuberculosis Cytochrome P450 51 Cyp51 (CYPL1) (P450-L1A1) (sterol 14-alpha demethylase) (lanosterol 14-alpha demethylase) (P450-14DM) 0.0019 0.0003 0.0024
Trichomonas vaginalis penicillin-binding protein, putative 0.0039 0.0062 0.0106
Trypanosoma brucei epsilon tubulin 0.1147 0.3352 0.5678
Loa Loa (eye worm) hypothetical protein 0.0152 0.04 0.0671
Schistosoma mansoni tubulin subunit gamma 0.1147 0.3352 0.5452
Trichomonas vaginalis tubulin epsilon chain, putative 0.2007 0.5904 1
Echinococcus granulosus chromobox protein 1 0.0075 0.017 0.0276
Schistosoma mansoni nuclear hormone receptor superfamily protein-related 0.0067 0.0146 0.0238
Leishmania major alpha tubulin 0.1526 0.4477 0.7583
Schistosoma mansoni hypothetical protein 0.0135 0.0349 0.0567
Brugia malayi beta-tubulin, identical 0.2007 0.5904 1
Echinococcus granulosus terminal deoxycytidyl transferase rev1 0.004 0.0066 0.0108
Trypanosoma cruzi zeta tubulin, putative 0.0498 0.1426 0.2415
Echinococcus multilocularis 0.0019 0.0003 0.0003
Leishmania major zeta tubulin, putative 0.0498 0.1426 0.2415
Echinococcus granulosus thyroid hormone receptor alpha 0.0067 0.0146 0.0238
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.0077 0.0176 0.0176
Echinococcus granulosus cathepsin L cysteine proteinase 0.002 0.0008 0.0013
Mycobacterium tuberculosis Probable cytochrome P450 130 Cyp130 0.0019 0.0003 0.0024
Mycobacterium tuberculosis Probable cytochrome P450 137 Cyp137 0.0019 0.0003 0.0024
Brugia malayi Papain family cysteine protease containing protein 0.002 0.0008 0.0013
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0067 0.0146 0.0673
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0152 0.04 0.0677
Chlamydia trachomatis ATP-dependent Clp protease proteolytic subunit 0.0094 0.0228 1
Schistosoma mansoni aldehyde dehydrogenase 0.0062 0.0132 0.0215
Echinococcus multilocularis RNA directed DNA polymerase (reverse transcriptase) 0.0018 0.0001 0.0001
Mycobacterium ulcerans cytochrome P450 125A7 Cyp125A7 0.0019 0.0003 0.0024
Schistosoma mansoni ecdysone-induced protein 78c (dr-78) 0.0085 0.0201 0.0327
Echinococcus multilocularis isocitrate dehydrogenase (NAD+) 0.0022 0.0013 0.0013
Echinococcus granulosus cytoplasmic intermediate filament protein 0.0027 0.0028 0.0046
Trypanosoma brucei histone deacetylase 1 0.0928 0.2702 0.4577
Brugia malayi steroid hormone receptor 0.0152 0.04 0.0677
Plasmodium vivax vivapain-2 0.002 0.0008 0.0013
Plasmodium vivax AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0077 0.0176 0.0299
Mycobacterium tuberculosis Probable cytochrome P450 136 Cyp136 0.0019 0.0003 0.0024
Loa Loa (eye worm) MH2 domain-containing protein 0.0092 0.0222 0.0371
Echinococcus granulosus isocitrate dehydrogenase NAD subunit 0.0022 0.0013 0.002
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.002 0.0008 0.0013
Mycobacterium ulcerans cytochrome P450 51B1 Cyp51B1 0.0019 0.0003 0.0024
Brugia malayi tubulin alpha-2 chain 0.1526 0.4477 0.7583
Toxoplasma gondii Zn-finger in ubiquitin-hydrolases domain-containing protein 0.0024 0.002 0.0033
Leishmania major beta tubulin 0.2007 0.5904 1
Trypanosoma brucei epsilon tubulin 0.1147 0.3352 0.5678
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0067 0.0146 0.0673
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0179 0.0481 0.0481
Echinococcus multilocularis musashi 0.0056 0.0114 0.0114
Brugia malayi hypothetical protein 0.0018 0.0001 0.0002
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.019 0.0511 0.0831
Leishmania major histone deacetylase, putative 0.0409 0.1163 0.197
Mycobacterium tuberculosis Probable reductase 0.0116 0.0291 0.2042
Echinococcus granulosus dna polymerase eta 0.004 0.0066 0.0108
Echinococcus granulosus tubulin delta chain 0.0498 0.1426 0.2319
Echinococcus granulosus peroxisome assembly protein 26 0.1526 0.4477 0.728
Leishmania major delta tubulin, putative 0.0498 0.1426 0.2415
Brugia malayi Smad1 0.0092 0.0222 0.0376
Loa Loa (eye worm) thioredoxin reductase 0.0051 0.0098 0.0161
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.002 0.0008 0.0013
Leishmania major alpha tubulin 0.1526 0.4477 0.7583
Echinococcus multilocularis tubulin alpha chain 0.1526 0.4477 0.4477
Giardia lamblia Reverse transcriptase/endonuclease, putative 0.0018 0.0001 0.0002
Trypanosoma cruzi histone deacetylase, putative 0.0409 0.1163 0.197
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0152 0.04 0.065
Leishmania major beta tubulin 0.2007 0.5904 1
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.002 0.0008 0.0013
Onchocerca volvulus Heterochromatin protein 1 homolog 0.0045 0.0082 0.0373
Mycobacterium ulcerans cytochrome P450 144A4 Cyp144A4 0.0019 0.0003 0.0024
Echinococcus multilocularis beta tubulin 0.2007 0.5904 0.5904
Giardia lamblia Ribonuclease H 0.0212 0.0578 0.098
Brugia malayi beta-lactamase 0.0039 0.0062 0.0106
Loa Loa (eye worm) alpha-tubulin 0.1526 0.4477 0.7581
Trypanosoma brucei zeta tubulin, putative 0.0498 0.1426 0.2415
Echinococcus granulosus tubulin alpha 3 chain 0.1526 0.4477 0.728
Mycobacterium tuberculosis Probable aldehyde dehydrogenase 0.0062 0.0132 0.0928
Loa Loa (eye worm) hypothetical protein 0.0088 0.0208 0.0346
Echinococcus granulosus tubulin alpha 1C chain 0.1526 0.4477 0.728
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0019 0.0005 0.0008
Trichomonas vaginalis tubulin alpha chain, putative 0.0649 0.1874 0.3174
Toxoplasma gondii phosphofructokinase domain-containing protein 0.0031 0.0041 0.007
Plasmodium falciparum ATP-dependent Clp protease proteolytic subunit 0.0094 0.0228 0.0386
Brugia malayi orphan nuclear receptor NR2E1 0.0067 0.0146 0.0248
Echinococcus granulosus dihydrofolate reductase 0.0047 0.0087 0.0142
Mycobacterium leprae DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE 0.0129 0.033 0.2292
Giardia lamblia DINP protein human, muc B family 0.004 0.0066 0.0112
Echinococcus granulosus nuclear receptor subfamily 4 group A 0.0067 0.0146 0.0238
Brugia malayi Steroid receptor seven-up type 2 0.0152 0.04 0.0677
Trichomonas vaginalis tubulin, putative 0.0649 0.1874 0.3174
Trypanosoma cruzi histone deacetylase, putative 0.0299 0.0834 0.1413
Loa Loa (eye worm) hypothetical protein 0.0103 0.0253 0.0423
Schistosoma mansoni cathepsin F (C01 family) 0.002 0.0008 0.0013
Trypanosoma brucei ribonuclease H1 0.0212 0.0578 0.098
Plasmodium vivax bifunctional dihydrofolate reductase-thymidylate synthase, putative 0.0162 0.0429 0.0727
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0077 0.0177 0.0299
Loa Loa (eye worm) flap endonuclease-1 0.0028 0.0031 0.0046
Loa Loa (eye worm) hypothetical protein 0.03 0.0838 0.1414
Echinococcus multilocularis cysteine protease 0.002 0.0008 0.0008
Echinococcus multilocularis 6 phosphofructokinase 0.0117 0.0294 0.0294
Trypanosoma brucei alpha tubulin 0.1526 0.4477 0.7583
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative 0.0077 0.0176 0.0299
Brugia malayi Tubulin alpha chain 0.1526 0.4477 0.7583
Echinococcus multilocularis thioredoxin glutathione reductase 0.0051 0.0098 0.0098
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0039 0.0062 0.01
Brugia malayi p25-alpha family protein 0.0392 0.1113 0.1885
Trichomonas vaginalis tubulin alpha chain, putative 0.2007 0.5904 1
Schistosoma mansoni tubulin subunit beta 0.2007 0.5904 0.9601
Schistosoma mansoni hypothetical protein 0.0018 0.0001 0.0002
Schistosoma mansoni lamin 0.0056 0.0114 0.0186
Entamoeba histolytica tartrate dehydrogenase, putative 0.0022 0.0013 0.0008
Toxoplasma gondii ABC1 family protein 0.0039 0.0062 0.0106
Mycobacterium ulcerans cytochrome P450 187A4 Cyp187A4 0.0019 0.0003 0.0024
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0077 0.0177 0.0299
Entamoeba histolytica hypothetical protein 0.0409 0.1161 0.1955
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.0039 0.0062 0.0438
Schistosoma mansoni Smad4 0.0041 0.007 0.0115
Toxoplasma gondii beta tubulin 0.2007 0.5904 1
Loa Loa (eye worm) CBP-B 0.0083 0.0194 0.0323
Loa Loa (eye worm) hypothetical protein 0.031 0.0869 0.1467
Mycobacterium tuberculosis Probable cytochrome P450 138 Cyp138 0.0019 0.0003 0.0024
Echinococcus granulosus cytochrome P450 2K1 0.0019 0.0003 0.0006
Leishmania major hypothetical protein, conserved 0.0039 0.0062 0.0106
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.0152 0.04 0.04
Brugia malayi histone deacetylase 3 (HD3) 0.0928 0.2702 0.4577
Trichomonas vaginalis chromobox protein, putative 0.0075 0.017 0.0287
Schistosoma mansoni phosphoglucomutase 0.0212 0.0578 0.094
Mycobacterium leprae PROBABLE 3-ISOPROPYLMALATE DEHYDROGENASE LEUB (BETA-IPM DEHYDROGENASE) (IMDH) (3-IPM-DH) 0.0022 0.0013 0.0064
Loa Loa (eye worm) p25-alpha family protein 0.0392 0.1113 0.188
Brugia malayi Helix-loop-helix DNA-binding domain containing protein 0.0116 0.0291 0.0494
Onchocerca volvulus 0.0649 0.1874 0.8705
Echinococcus multilocularis nuclear receptor nhr 48 0.0067 0.0146 0.0146
Plasmodium vivax hypothetical protein, conserved 0.0039 0.0062 0.0106
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0152 0.04 0.04
Mycobacterium tuberculosis Possible maturase 0.0018 0.0001 0.001
Trichomonas vaginalis tubulin alpha-1 chain, putative 0.0877 0.255 0.432
Trypanosoma cruzi DNA polymerase kappa, putative 0.004 0.0066 0.0112
Trichomonas vaginalis chromobox protein, putative 0.0075 0.017 0.0287
Toxoplasma gondii alpha-tubulin I, putative 0.1526 0.4477 0.7583
Loa Loa (eye worm) hypothetical protein 0.0067 0.0146 0.0242
Plasmodium vivax histone deacetylase, putative 0.0409 0.1163 0.197
Loa Loa (eye worm) hypothetical protein 0.0928 0.2702 0.4574
Brugia malayi Tubulin beta chain 0.0498 0.1426 0.2415
Mycobacterium tuberculosis Probable endonuclease IV End (endodeoxyribonuclease IV) (apurinase) 0.0082 0.0192 0.1345
Leishmania major beta tubulin 0.2007 0.5904 1
Trichomonas vaginalis tubulin, putative 0.2007 0.5904 1
Mycobacterium tuberculosis Probable cytochrome P450 124 Cyp124 0.0019 0.0003 0.0024
Trypanosoma brucei Endonuclease-reverse transcriptase/Reverse transcriptase (RNA-dependent DNA polymerase), putative 0.0018 0.0001 0.0002
Mycobacterium ulcerans cytochrome P450 136A2 Cyp136A2 0.0019 0.0003 0.0024
Trypanosoma brucei Ring finger domain/Zn-finger in ubiquitin-hydrolases and other protein, putative 0.0024 0.002 0.0033
Onchocerca volvulus 0.002 0.0008 0.003
Schistosoma mansoni hypothetical protein 0.0106 0.0261 0.0425
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0064 0.0139 0.0226
Brugia malayi MH2 domain containing protein 0.1356 0.3973 0.673
Mycobacterium ulcerans cytochrome P450 150A6 Cyp150A6 0.0019 0.0003 0.0024
Trichomonas vaginalis tubulin alpha-1 chain, putative 0.1526 0.4477 0.7583
Mycobacterium ulcerans cytochrome P450 108B4 Cyp108B4 0.0019 0.0003 0.0024
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0077 0.0177 0.0299
Schistosoma mansoni cpg binding protein 0.0031 0.0039 0.0064
Schistosoma mansoni 6-phosphofructokinase 0.0117 0.0294 0.0478
Plasmodium falciparum ATP-dependent 6-phosphofructokinase 0.0031 0.0041 0.007
Echinococcus multilocularis mothers against decapentaplegic 5 0.0092 0.0222 0.0222
Giardia lamblia Reverse transcriptase/endonuclease, putative 0.0018 0.0001 0.0002
Trichomonas vaginalis histone deacetylase 1, 2 ,3, putative 0.0928 0.2702 0.4577
Loa Loa (eye worm) hypothetical protein 0.0094 0.0228 0.0381
Trichomonas vaginalis phosphofructokinase, putative 0.0031 0.0041 0.007
Loa Loa (eye worm) MH2 domain-containing protein 0.1356 0.3973 0.6728
Giardia lamblia Hypothetical protein 0.0028 0.003 0.0052
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.0152 0.04 0.0671
Schistosoma mansoni cellular tumor antigen P53 0.0103 0.0253 0.0411
Trypanosoma cruzi PAB1-binding protein , putative 0.0178 0.0477 0.0808
Echinococcus granulosus histone acetyltransferase KAT2B 0.0297 0.0828 0.1347
Trichomonas vaginalis tubulin, putative 0.0498 0.1426 0.2415
Mycobacterium ulcerans putative regulatory protein 0.0039 0.0062 0.0438
Brugia malayi glutathione reductase 0.0051 0.0098 0.0167
Trypanosoma brucei DNA polymerase kappa, putative 0.004 0.0066 0.0112
Plasmodium vivax ubiquitin carboxyl-terminal hydrolase 13, putative 0.0028 0.003 0.0052
Trypanosoma cruzi flap endonuclease-1 (FEN-1), putative 0.0028 0.0031 0.0052
Echinococcus multilocularis BRCA1 associated protein 0.0024 0.002 0.002
Brugia malayi Tubulin gamma chain 0.1147 0.3352 0.5678
Brugia malayi nuclear receptor NHR-88 0.0067 0.0146 0.0248
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0064 0.0139 0.0139
Brugia malayi RNase H family protein 0.0212 0.0578 0.098
Echinococcus granulosus TGF beta signal transducer SmadC 0.0092 0.0222 0.0361
Echinococcus granulosus Nuclear hormone receptor HR96 0.0067 0.0146 0.0238
Trypanosoma brucei DNA polymerase IV, putative 0.004 0.0066 0.0112
Echinococcus multilocularis retinoic acid receptor rxr beta a retinoic acid receptor rxr alpha a retinoic acid receptor rxr alpha 0.0173 0.046 0.046
Trypanosoma cruzi ribonuclease H1, putative 0.0212 0.0578 0.098
Trichomonas vaginalis tubulin alpha chain, putative 0.0649 0.1874 0.3174
Mycobacterium ulcerans ATP-dependent Clp protease proteolytic subunit 0.0094 0.0228 0.16
Loa Loa (eye worm) cytochrome P450 family protein 0.0079 0.0182 0.0302
Trichomonas vaginalis tubulin alpha chain, putative 0.0649 0.1874 0.3174
Echinococcus granulosus histone deacetylase 3 0.0928 0.2702 0.4395
Brugia malayi Histone deacetylase 1 0.0928 0.2702 0.4577
Loa Loa (eye worm) pax transcription factor protein 2 0.0743 0.2153 0.3643
Mycobacterium ulcerans cytochrome P450 185A4 Cyp185A4 0.0028 0.0031 0.022
Echinococcus multilocularis tubulin alpha chain 0.1526 0.4477 0.4477
Echinococcus multilocularis tubulin subunit TubB 0.1526 0.4477 0.4477
Brugia malayi 6-phosphofructokinase 0.0117 0.0294 0.0498
Schistosoma mansoni tubulin subunit epsilon 0.1147 0.3352 0.5452
Echinococcus multilocularis histone deacetylase 7 0.0409 0.1163 0.1163
Echinococcus multilocularis RNA directed DNA polymerase (reverse transcriptase) 0.0018 0.0001 0.0001
Brugia malayi Muscleblind-like protein 0.031 0.0869 0.1472
Plasmodium falciparum ubiquitin carboxyl-terminal hydrolase, putative 0.0024 0.002 0.0033
Brugia malayi ImpB/MucB/SamB family protein 0.004 0.0066 0.0112
Loa Loa (eye worm) hypothetical protein 0.0067 0.0146 0.0242
Plasmodium vivax histone deacetylase, putative 0.0299 0.0834 0.1413
Plasmodium falciparum bifunctional dihydrofolate reductase-thymidylate synthase 0.0162 0.0429 0.0727
Trypanosoma cruzi zeta tubulin, putative 0.0498 0.1426 0.2415
Entamoeba histolytica tubulin family protein 0.2007 0.5904 1
Brugia malayi Cathepsin L-like precursor 0.002 0.0008 0.0013
Loa Loa (eye worm) MH1 domain-containing protein 0.0092 0.0222 0.0371
Trichomonas vaginalis ribonuclease H1, putative 0.0212 0.0578 0.098
Echinococcus granulosus ribonuclease H1 0.0212 0.0578 0.094
Brugia malayi Pao retrotransposon peptidase family protein 0.0018 0.0001 0.0002
Brugia malayi bHLH-PAS transcription factor 0.0039 0.0062 0.0106
Entamoeba histolytica hypothetical protein 0.0409 0.1161 0.1955
Schistosoma mansoni smad 0.0092 0.0222 0.0361
Onchocerca volvulus 0.0152 0.04 0.1851
Echinococcus granulosus Tubulin beta 2C chain 0.2007 0.5904 0.9601
Loa Loa (eye worm) cysteine protease 0.002 0.0008 0.0007
Brugia malayi PAS domain containing protein 0.0052 0.0103 0.0174
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0077 0.0177 0.0299
Echinococcus multilocularis Tubulin alpha 1 chain 0.1526 0.4477 0.4477
Echinococcus granulosus jun protein 0.009 0.0215 0.035
Onchocerca volvulus 0.0743 0.2153 1
Trichomonas vaginalis D-aminoacylase, putative 0.0039 0.0062 0.0106
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.002 0.0008 0.0013
Plasmodium falciparum ubiquitin carboxyl-terminal hydrolase 13, putative 0.0028 0.003 0.0052
Schistosoma mansoni jun-related protein 0.0073 0.0165 0.0268
Onchocerca volvulus Cathepsin L homolog 0.002 0.0008 0.003
Echinococcus granulosus tubulin alpha 1C chain 0.1526 0.4477 0.728
Brugia malayi Probable ClpP-like protease 0.0094 0.0228 0.0386
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 5 0.0028 0.003 0.003
Leishmania major alpha tubulin 0.1526 0.4477 0.7583
Trichomonas vaginalis phosphofructokinase, putative 0.0031 0.0041 0.007
Brugia malayi reverse transcriptase 0.0018 0.0001 0.0002
Schistosoma mansoni isocitrate dehydrogenase 0.0022 0.0013 0.002
Leishmania major beta tubulin 0.2007 0.5904 1
Loa Loa (eye worm) histone deacetylase 0.0409 0.1163 0.1965
Plasmodium vivax tubulin beta chain, putative 0.2007 0.5904 1
Trypanosoma brucei DNA polymerase kappa, putative 0.004 0.0066 0.0112
Brugia malayi Pre-SET motif family protein 0.0445 0.1268 0.2148
Mycobacterium ulcerans cell division protein FtsZ 0.0498 0.1426 1
Echinococcus multilocularis tubulin delta chain 0.0498 0.1426 0.1426
Loa Loa (eye worm) 6-phosphofructokinase 0.0117 0.0294 0.0492
Brugia malayi Nuclear hormone receptor family member nhr-41 0.0152 0.04 0.0677
Brugia malayi BRCA1-associated protein 2 containing protein 0.0024 0.002 0.0033
Brugia malayi Tubulin alpha-2 chain 0.1526 0.4477 0.7583
Mycobacterium tuberculosis Probable cytochrome P450 140 Cyp140 0.0019 0.0003 0.0024
Loa Loa (eye worm) hypothetical protein 0.002 0.0008 0.0007
Onchocerca volvulus 0.0039 0.0062 0.0284
Trichomonas vaginalis tubulin beta chain, putative 0.1526 0.4477 0.7583
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.002 0.0008 0.0013
Loa Loa (eye worm) hypothetical protein 0.0152 0.04 0.0671
Schistosoma mansoni single-minded 0.0052 0.0103 0.0167
Mycobacterium tuberculosis Probable cytochrome P450 143 Cyp143 0.0019 0.0003 0.0024
Echinococcus granulosus beta LACTamase domain containing family member 0.0039 0.0062 0.0102
Trypanosoma brucei tubulin delta chain 0.0498 0.1426 0.2415
Loa Loa (eye worm) hypothetical protein 0.0056 0.0114 0.0188
Brugia malayi Nuclear hormone receptor family member nhr-31 0.0152 0.04 0.0677
Echinococcus granulosus Tubulin beta 2C chain 0.2007 0.5904 0.9601
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.0077 0.0176 0.0287
Loa Loa (eye worm) thymidylate synthase 0.0115 0.029 0.0485
Loa Loa (eye worm) hypothetical protein 0.0152 0.04 0.0671
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.0152 0.04 0.065
Plasmodium vivax tubulin gamma chain, putative 0.1147 0.3352 0.5678
Loa Loa (eye worm) hypothetical protein 0.0067 0.0146 0.0242
Mycobacterium tuberculosis Probable dehydrogenase 0.0116 0.0291 0.2042
Echinococcus multilocularis peptidase Clp (S14 family) 0.0062 0.0132 0.0132
Echinococcus multilocularis Tubulin alpha 1 chain 0.1526 0.4477 0.4477
Entamoeba histolytica tubulin family protein 0.2007 0.5904 1
Echinococcus granulosus thymidylate synthase 0.0115 0.029 0.0471
Brugia malayi ecdysone receptor 0.0067 0.0146 0.0248
Brugia malayi nuclear receptor RXR 0.0067 0.0146 0.0248
Brugia malayi nuclear hormone receptor 0.0067 0.0146 0.0248
Echinococcus granulosus tubulin alpha chain 0.1526 0.4477 0.728
Trypanosoma brucei RNA helicase, putative 0.0796 0.2312 0.3916
Echinococcus multilocularis thyroid hormone receptor alpha 0.0287 0.08 0.08
Schistosoma mansoni nuclear receptor nhr-48 0.0067 0.0146 0.0238
Echinococcus granulosus lysine specific demethylase 5A 0.0061 0.0129 0.0209
Onchocerca volvulus 0.0039 0.0062 0.0284
Brugia malayi beta-lactamase family protein 0.0039 0.0062 0.0106
Schistosoma mansoni CREB-binding protein 1 (SmCBP1) 0.0116 0.0293 0.0476
Trichomonas vaginalis tubulin alpha chain, putative 0.1147 0.3352 0.5678
Echinococcus granulosus isocitrate dehydrogenase NAD 0.0022 0.0013 0.002
Loa Loa (eye worm) tubulin beta chain 0.2007 0.5904 1
Trypanosoma cruzi isocitrate dehydrogenase, putative 0.0179 0.0481 0.0814
Toxoplasma gondii histone deacetylase HDAC3 0.0928 0.2702 0.4577
Loa Loa (eye worm) hypothetical protein 0.0067 0.0146 0.0242
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0028 0.003 0.0052
Loa Loa (eye worm) hypothetical protein 0.0067 0.0146 0.0242
Trichomonas vaginalis histone deacetylase 1, 2 ,3, putative 0.0928 0.2702 0.4577
Brugia malayi Pao retrotransposon peptidase family protein 0.0018 0.0001 0.0002
Entamoeba histolytica acetyltransferase, GNAT family 0.0082 0.0192 0.0312
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0028 0.003 0.0052
Plasmodium vivax ATP-dependent Clp protease proteolytic subunit, putative 0.0033 0.0044 0.0075
Leishmania major alpha tubulin 0.1526 0.4477 0.7583
Chlamydia trachomatis endonuclease IV 0.0082 0.0192 0.8409
Schistosoma mansoni hypothetical protein 0.014 0.0363 0.059
Trichomonas vaginalis esterase, putative 0.0039 0.0062 0.0106
Onchocerca volvulus 0.002 0.0008 0.003
Leishmania major beta tubulin 0.2007 0.5904 1
Echinococcus granulosus transcription factor eb 0.0116 0.0291 0.0474
Trichomonas vaginalis set domain proteins, putative 0.0506 0.145 0.2456
Trichomonas vaginalis tubulin alpha-1 chain, putative 0.0649 0.1874 0.3174
Plasmodium vivax SET domain protein, putative 0.0064 0.0139 0.0235
Plasmodium falciparum tubulin epsilon chain, putative 0.1147 0.3352 0.5678
Echinococcus multilocularis u4:u6.u5 tri snrnp associated protein 2 0.0028 0.003 0.003
Schistosoma mansoni hypothetical protein 0.0065 0.014 0.0227
Trypanosoma brucei flap endonuclease-1 (FEN-1), putative 0.0028 0.0031 0.0052
Leishmania major dihydrofolate reductase-thymidylate synthase 0.0162 0.0429 0.0727
Onchocerca volvulus 0.0031 0.0039 0.0176
Toxoplasma gondii cytochrome p450 superfamily protein 0.0019 0.0003 0.0006
Loa Loa (eye worm) isocitrate dehydrogenase gamma subunit 0.0022 0.0013 0.0015
Loa Loa (eye worm) hypothetical protein 0.0085 0.0201 0.0335
Onchocerca volvulus 0.03 0.0838 0.3888
Echinococcus multilocularis RNA directed DNA polymerase 0.0018 0.0001 0.0001
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0152 0.04 0.065
Giardia lamblia Epsilon tubulin 0.0498 0.1426 0.2415
Mycobacterium tuberculosis Conserved protein 0.0039 0.0062 0.0438
Mycobacterium ulcerans endonuclease IV 0.0082 0.0192 0.1345
Trichomonas vaginalis reverse transcriptases, putative 0.0018 0.0001 0.0002
Loa Loa (eye worm) hypothetical protein 0.0067 0.0146 0.0242
Echinococcus granulosus beta tubulin 0.2007 0.5904 0.9601
Mycobacterium tuberculosis Probable 3-isopropylmalate dehydrogenase LeuB (beta-IPM dehydrogenase) (IMDH) (3-IPM-DH) 0.0022 0.0013 0.0088
Schistosoma mansoni histone deacetylase 0.0928 0.2702 0.4395
Echinococcus multilocularis Tubulin beta 2C chain 0.2007 0.5904 0.5904
Schistosoma mansoni aldehyde dehydrogenase 0.0062 0.0132 0.0215
Loa Loa (eye worm) hypothetical protein 0.0051 0.0099 0.0162
Echinococcus multilocularis histone deacetylase 6 0.0434 0.1235 0.1235
Trypanosoma cruzi cruzipain precursor, putative 0.0077 0.0177 0.0299
Brugia malayi hypothetical protein 0.0067 0.0146 0.0248
Loa Loa (eye worm) hypothetical protein 0.0877 0.255 0.4317
Echinococcus multilocularis RNA directed DNA polymerase (reverse transcriptase) 0.0018 0.0001 0.0001
Plasmodium falciparum histone deacetylase 2 0.0409 0.1163 0.197
Echinococcus multilocularis nuclear receptor subfamily 1 group D 0.0085 0.0201 0.0201
Loa Loa (eye worm) ctsf protein 0.002 0.0008 0.0007
Loa Loa (eye worm) hypothetical protein 0.0026 0.0025 0.0037
Schistosoma mansoni hypothetical protein 0.0796 0.2312 0.376
Plasmodium falciparum histone deacetylase 1 0.0928 0.2702 0.4577
Plasmodium vivax flap endonuclease 1, putative 0.0028 0.0031 0.0052
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0039 0.0062 0.0106
Mycobacterium ulcerans cytochrome P450 140A5 Cyp140A5 0.0019 0.0003 0.0024
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0039 0.0062 0.0102
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0065 0.014 0.0227
Plasmodium falciparum thioredoxin reductase 0.0051 0.0098 0.0167
Echinococcus granulosus tubulin beta 4A class IVa 0.2007 0.5904 0.9601
Loa Loa (eye worm) cytochrome P450 family protein 0.0028 0.0031 0.0047
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.002 0.0008 0.0013
Brugia malayi Cytochrome P450 family protein 0.0028 0.0031 0.0053
Toxoplasma gondii aldehyde dehydrogenase 0.0062 0.0132 0.0224
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0028 0.003 0.0052
Trypanosoma cruzi beta tubulin, putative 0.2007 0.5904 1
Schistosoma mansoni intermediate filament proteins 0.0056 0.0114 0.0186
Loa Loa (eye worm) hypothetical protein 0.0179 0.0479 0.0807
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0065 0.014 0.014
Trichomonas vaginalis DNA polymerase eta, putative 0.004 0.0066 0.0112
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.0077 0.0176 0.0299
Brugia malayi Tubulin beta-1 chain 0.2007 0.5904 1
Trichomonas vaginalis phosphofructokinase, putative 0.0117 0.0294 0.0498
Schistosoma mansoni terminal deoxycytidyl transferase 0.004 0.0066 0.0108
Echinococcus multilocularis Mitotic checkpoint protein PRCC, C terminal 0.0135 0.0349 0.0349
Schistosoma mansoni cytochrome P450 0.0019 0.0003 0.0006
Echinococcus multilocularis cysteine protease 0.002 0.0008 0.0008
Mycobacterium tuberculosis Conserved hypothetical protein 0.004 0.0066 0.0464
Onchocerca volvulus 0.0115 0.029 0.1341
Trypanosoma brucei alpha tubulin, putative 0.0649 0.1874 0.3174
Brugia malayi tailless protein 0.0067 0.0146 0.0248
Loa Loa (eye worm) hypothetical protein 0.0039 0.0062 0.01
Giardia lamblia Beta tubulin 0.2007 0.5904 1
Echinococcus multilocularis nuclear receptor subfamily 4 group A 0.0067 0.0146 0.0146
Loa Loa (eye worm) hypothetical protein 0.0152 0.04 0.0671
Echinococcus granulosus Tubulin alpha 1 chain 0.1526 0.4477 0.728
Mycobacterium ulcerans ATP-dependent Clp protease proteolytic subunit 0.0094 0.0228 0.16
Loa Loa (eye worm) ubiquitin specific peptidase 39 0.0028 0.003 0.0046
Mycobacterium ulcerans thymidylate synthase 0.0115 0.029 0.2033
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.019 0.0511 0.0831
Loa Loa (eye worm) hypothetical protein 0.0039 0.0062 0.01
Echinococcus multilocularis Tubulin beta 2C chain 0.2007 0.5904 0.5904
Loa Loa (eye worm) tubulin beta-2A chain 0.2007 0.5904 1
Loa Loa (eye worm) tubulin alpha-3 chain 0.0877 0.255 0.4317
Trypanosoma brucei SLACS retrotransposable element (part), putative 0.0018 0.0001 0.0002
Schistosoma mansoni coup transcription factor 0.0152 0.04 0.065
Brugia malayi Nuclear hormone receptor family member nhr-3 0.0152 0.04 0.0677
Trypanosoma brucei isocitrate dehydrogenase, putative 0.0179 0.0481 0.0814
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0064 0.0139 0.0226
Schistosoma mansoni cpg binding protein 0.0033 0.0044 0.0072
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.002 0.0008 0.0013
Trypanosoma cruzi histone deacetylase 1, putative 0.0928 0.2702 0.4577
Trypanosoma cruzi hypothetical protein, conserved 0.0039 0.0062 0.0106
Onchocerca volvulus 0.002 0.0008 0.003
Trichomonas vaginalis histone deacetylase, putative 0.0928 0.2702 0.4577
Echinococcus granulosus histone deacetylase 7 0.0409 0.1163 0.1891
Loa Loa (eye worm) helix-loop-helix DNA-binding domain-containing protein 0.0115 0.029 0.0485
Schistosoma mansoni brca1-associated protein (brap2) 0.0024 0.002 0.0032
Brugia malayi beta-lactamase family protein 0.0039 0.0062 0.0106
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.0152 0.04 0.0671
Loa Loa (eye worm) follicle stimulating hormone receptor 0.0254 0.07 0.1181
Treponema pallidum diphosphate--fructose-6-phosphate 1-phosphotransferase 0.0117 0.0294 0.2061
Brugia malayi Pax transcription factor protein 2 0.0743 0.2153 0.3646
Trypanosoma brucei DNA polymerase kappa, putative 0.004 0.0066 0.0112
Schistosoma mansoni phosphoglucomutase 0.0212 0.0578 0.094
Mycobacterium ulcerans cytochrome P450 189A7 Cyp189A7 0.0019 0.0003 0.0024
Schistosoma mansoni rab geranylgeranyl transferase alpha subunit 0.004 0.0066 0.0108
Onchocerca volvulus Heterochromatin protein 1 homolog 0.0042 0.0072 0.0329
Echinococcus multilocularis Tubulin beta 2C chain 0.2007 0.5904 0.5904
Schistosoma mansoni alpha tubulin 0.1526 0.4477 0.728
Trichomonas vaginalis ap endonuclease, putative 0.0077 0.0176 0.0299
Schistosoma mansoni ap endonuclease 0.0077 0.0176 0.0287
Echinococcus granulosus lamin dm0 0.0056 0.0114 0.0186
Trypanosoma cruzi cytochrome p450-like protein, putative 0.0019 0.0003 0.0006
Echinococcus multilocularis histone deacetylase 8 0.0299 0.0834 0.0834
Mycobacterium ulcerans lipase LipD 0.0039 0.0062 0.0438
Echinococcus granulosus nuclear receptor subfamily 1 group D 0.0085 0.0201 0.0327
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.0152 0.04 0.0671
Plasmodium vivax apurinic/apyrimidinic endonuclease Apn1, putative 0.0082 0.0192 0.0325
Loa Loa (eye worm) histone deacetylase 11 0.0299 0.0834 0.1408
Mycobacterium tuberculosis Probable membrane NADH dehydrogenase NdhA 0.0116 0.0291 0.2042
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0019 0.0005 0.0008
Loa Loa (eye worm) hypothetical protein 0.0039 0.0062 0.01
Mycobacterium tuberculosis Possible cytochrome P450 135B1 Cyp135B1 0.0019 0.0003 0.0024
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase domain containing protein 0.0028 0.003 0.0038
Trichomonas vaginalis phosphofructokinase, putative 0.0031 0.0041 0.007
Loa Loa (eye worm) hypothetical protein 0.004 0.0066 0.0106
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase 5, putative 0.0028 0.003 0.0038
Loa Loa (eye worm) cytoplasmic intermediate filament protein 0.003 0.0037 0.0057
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.002 0.0008 0.0013
Trichomonas vaginalis tubulin epsilon chain, putative 0.0498 0.1426 0.2415
Echinococcus multilocularis dihydrofolate reductase 0.0047 0.0087 0.0087
Loa Loa (eye worm) hypothetical protein 0.0085 0.0201 0.0335
Onchocerca volvulus 0.0039 0.0064 0.0292
Schistosoma mansoni 6-phosphofructokinase 0.0117 0.0294 0.0478
Echinococcus multilocularis tubulin alpha chain 0.1526 0.4477 0.4477
Loa Loa (eye worm) hypothetical protein 0.0067 0.0146 0.0242
Leishmania major ATP-dependent phosphofructokinase 0.0117 0.0294 0.0498
Loa Loa (eye worm) hypothetical protein 0.0039 0.0062 0.01
Loa Loa (eye worm) beta-lactamase 0.0039 0.0062 0.01
Leishmania major cytochrome p450-like protein 0.0019 0.0003 0.0006
Plasmodium falciparum tubulin delta chain, putative 0.0498 0.1426 0.2415
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.0152 0.04 0.065
Brugia malayi photoreceptor-specific nuclear receptor 0.0152 0.04 0.0677
Brugia malayi jmjC domain containing protein 0.0059 0.0123 0.0209
Plasmodium falciparum alpha tubulin 1 0.1526 0.4477 0.7583
Brugia malayi Pao retrotransposon peptidase family protein 0.0018 0.0001 0.0002
Giardia lamblia Flap structure-specific endonuclease 0.0028 0.0031 0.0052
Trypanosoma brucei cytochrome P450, putative 0.0028 0.0031 0.0053
Toxoplasma gondii beta-tubulin, putative 0.2007 0.5904 1
Loa Loa (eye worm) hypothetical protein 0.0082 0.0192 0.0319
Echinococcus granulosus histone deacetylase 6 0.0434 0.1235 0.2008
Loa Loa (eye worm) tubulin alpha-2 chain 0.1526 0.4477 0.7581
Trichomonas vaginalis tubulin beta-1 chain, putative 0.0498 0.1426 0.2415
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.002 0.0008 0.0013
Schistosoma mansoni Smad4 0.0041 0.007 0.0115
Trichomonas vaginalis tubulin gamma chain, putative 0.0498 0.1426 0.2415
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0065 0.014 0.0227
Trypanosoma cruzi Ring finger domain/Zn-finger in ubiquitin-hydrolases and other protein, putative 0.0024 0.002 0.0033
Wolbachia endosymbiont of Brugia malayi isocitrate dehydrogenase 0.0022 0.0013 0.0088
Loa Loa (eye worm) histone deacetylase 1 0.0928 0.2702 0.4574
Toxoplasma gondii ubiquitin specific protease 39 isoform 2, putative 0.0028 0.003 0.0052
Plasmodium vivax histone deacetylase 1, putative 0.0928 0.2702 0.4577
Schistosoma mansoni ap endonuclease 0.0077 0.0176 0.0287
Leishmania major cathepsin L-like protease 0.0077 0.0177 0.0299
Echinococcus multilocularis CREB binding protein 0.0018 0.0001 0.0001
Leishmania major flap endonuclease-1 (FEN-1), putative 0.0028 0.0031 0.0052
Plasmodium vivax glutathione reductase, putative 0.0051 0.0098 0.0167
Giardia lamblia Gamma tubulin 0.1147 0.3352 0.5678
Loa Loa (eye worm) hypothetical protein 0.0299 0.0834 0.1408
Schistosoma mansoni thyroid hormone receptor 0.0287 0.08 0.1302
Plasmodium falciparum cysteine proteinase falcipain 2a 0.002 0.0008 0.0013
Trypanosoma brucei unspecified product 0.004 0.0066 0.0112
Onchocerca volvulus 0.0071 0.0158 0.0727
Brugia malayi Zinc knuckle family protein 0.0018 0.0001 0.0002
Onchocerca volvulus 0.0067 0.0146 0.0673
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0065 0.014 0.0237
Trypanosoma brucei DNA polymerase kappa, putative 0.004 0.0066 0.0112
Schistosoma mansoni hypothetical protein 0.008 0.0185 0.0301
Entamoeba histolytica hypothetical protein 0.0409 0.1161 0.1955
Brugia malayi dihydrofolate reductase family protein 0.0047 0.0087 0.0148
Echinococcus multilocularis histone deacetylase 0.0409 0.1163 0.1163
Trypanosoma cruzi DNA polymerase kappa, putative 0.004 0.0066 0.0112
Plasmodium vivax tubulin epsilon chain, putative 0.1147 0.3352 0.5678
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.019 0.0511 0.0511
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.0152 0.04 0.065
Loa Loa (eye worm) nuclear hormone receptor 0.0067 0.0146 0.0242
Trypanosoma cruzi apurinic/apyrimidinic endonuclease 0.0077 0.0176 0.0299
Brugia malayi 6-phosphofructokinase 0.0117 0.0294 0.0498
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0065 0.014 0.014
Schistosoma mansoni brca1-associated protein (brap2) 0.0024 0.002 0.0032
Echinococcus multilocularis RNA directed DNA polymerase (reverse transcriptase) 0.0018 0.0001 0.0001
Brugia malayi isocitrate dehydrogenase [NAD] subunit beta, mitochondrial 0.0022 0.0013 0.0021
Entamoeba histolytica tubulin gamma chain 0.1147 0.3352 0.5672
Plasmodium vivax U4/U6.U5 tri-snRNP-associated protein 2, putative 0.0028 0.003 0.0052
Plasmodium falciparum tubulin beta chain 0.2007 0.5904 1
Toxoplasma gondii LsmAD domain-containing protein 0.0178 0.0477 0.0808
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0064 0.0139 0.0235
Trichomonas vaginalis BRCA1-associated protein, putative 0.0024 0.002 0.0033
Trypanosoma cruzi trypanothione reductase, putative 0.0051 0.0098 0.0167
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0152 0.04 0.0677
Loa Loa (eye worm) BRCA1-associated protein 2 containing protein 0.0024 0.002 0.0028
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.002 0.0008 0.0013
Schistosoma mansoni histone deacetylase 4 5 0.0409 0.1163 0.1891
Trichomonas vaginalis tubulin beta chain, putative 0.1526 0.4477 0.7583
Brugia malayi MH2 domain containing protein 0.0041 0.007 0.0119
Schistosoma mansoni histone deacetylase hda2 0.0299 0.0834 0.1357
Loa Loa (eye worm) latrophilin receptor protein 2 0.0065 0.014 0.0231
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0409 0.1161 0.1161
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0039 0.0062 0.0102
Brugia malayi acetyltransferase, GNAT family protein 0.0307 0.0859 0.1455
Echinococcus multilocularis CREB binding protein 0.0082 0.0191 0.0191
Trichomonas vaginalis phosphofructokinase, putative 0.0031 0.0041 0.007
Echinococcus multilocularis transcription factor eb 0.0116 0.0291 0.0291
Schistosoma mansoni hypothetical protein 0.0073 0.0165 0.0268
Onchocerca volvulus 0.0077 0.0175 0.0808
Brugia malayi Nuclear hormone receptor family member nhr-49 0.0152 0.04 0.0677
Echinococcus granulosus dna polymerase kappa 0.004 0.0066 0.0108
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.0152 0.04 0.0671
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.0077 0.0176 0.0293
Brugia malayi Nuclear hormone receptor family member nhr-14 0.0152 0.04 0.0677
Schistosoma mansoni unc-13 (munc13) 0.0022 0.0013 0.002
Loa Loa (eye worm) nuclear factor I 0.0051 0.01 0.0163
Toxoplasma gondii histone deacetylase HDAC1 0.0409 0.1163 0.197
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0019 0.0005 0.0008
Echinococcus granulosus Tubulin beta 2C chain 0.2007 0.5904 0.9601
Toxoplasma gondii tubulin/FtsZ family, GTPase domain-containing protein 0.0498 0.1426 0.2415
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.002 0.0008 0.0013
Brugia malayi Flap endonuclease-1 0.0028 0.0031 0.0052
Trypanosoma brucei unspecified product 0.023 0.0632 0.107
Trypanosoma cruzi Zn-finger in ubiquitin-hydrolases and other protein, putative 0.0024 0.002 0.0033
Leishmania major isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0179 0.0481 0.0814
Trichomonas vaginalis D-aminoacylase, putative 0.0039 0.0062 0.0106
Echinococcus multilocularis lysine specific demethylase 5A 0.0059 0.0123 0.0123
Trichomonas vaginalis tubulin, putative 0.0649 0.1874 0.3174
Leishmania major alpha tubulin 0.1526 0.4477 0.7583
Brugia malayi Cytochrome P450 family protein 0.0028 0.0031 0.0053
Loa Loa (eye worm) nuclear receptor NHR-67 0.0067 0.0146 0.0242
Giardia lamblia Histone deacetylase 0.0928 0.2702 0.4577
Brugia malayi latrophilin 2 splice variant baaae 0.014 0.0363 0.0614
Leishmania major histone deacetylase, putative 0.0409 0.1163 0.197
Brugia malayi exodeoxyribonuclease III family protein 0.0077 0.0176 0.0299
Giardia lamblia Beta tubulin 0.2007 0.5904 1
Leishmania major alpha tubulin 0.1526 0.4477 0.7583
Loa Loa (eye worm) hypothetical protein 0.1526 0.4477 0.7581
Echinococcus multilocularis Tubulin beta 2C chain 0.2007 0.5904 0.5904
Loa Loa (eye worm) transcription factor SMAD2 0.1356 0.3973 0.6728
Echinococcus granulosus beta tubulin 0.2007 0.5904 0.9601
Plasmodium vivax vivapain-2 0.002 0.0008 0.0013
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.002 0.0008 0.0013
Plasmodium vivax tubulin alpha chain, putative 0.1526 0.4477 0.7583
Echinococcus multilocularis cathepsin l cysteine peptidase 0.002 0.0008 0.0008
Trichomonas vaginalis penicillin-binding protein, putative 0.0039 0.0062 0.0106
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0067 0.0146 0.0146
Echinococcus multilocularis RNA directed DNA polymerase (reverse transcriptase) 0.0018 0.0001 0.0001
Trypanosoma brucei ingi protein (ORF1) 0.023 0.0632 0.107
Brugia malayi Nuclear hormone receptor-like 1 0.0085 0.0201 0.0341
Trypanosoma cruzi tubulin delta chain 0.0498 0.1426 0.2415
Leishmania major beta tubulin 0.2007 0.5904 1
Brugia malayi Nuclear hormone receptor E75 0.0067 0.0146 0.0248
Loa Loa (eye worm) alpha-tubulin 0.1526 0.4477 0.7581
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0152 0.04 0.0677
Schistosoma mansoni tubulin subunit beta 0.2007 0.5904 0.9601
Schistosoma mansoni hypothetical protein 0.0409 0.1161 0.1888
Brugia malayi Tubulin alpha chain 0.0498 0.1426 0.2415
Echinococcus granulosus ATP dependent Clp protease proteolytic subunit 0.0094 0.0228 0.0371
Mycobacterium tuberculosis Probable oxidoreductase 0.0129 0.033 0.2311
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.0152 0.04 0.065
Schistosoma mansoni nuclear receptor 0.0067 0.0146 0.0238
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.019 0.0511 0.0866
Wolbachia endosymbiont of Brugia malayi ATP-dependent Clp protease proteolytic subunit 0.0094 0.0228 0.16
Schistosoma mansoni smad1 5 8 and 0.0092 0.0222 0.0361
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.019 0.0511 0.0831
Brugia malayi Nuclear hormone receptor E75 0.0067 0.0146 0.0248
Giardia lamblia Alpha-tubulin 0.1526 0.4477 0.7583
Toxoplasma gondii cathepsin CPL 0.002 0.0008 0.0013
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0064 0.0139 0.0139
Trypanosoma cruzi isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0179 0.0481 0.0814
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0019 0.0005 0.0008
Trichomonas vaginalis conserved hypothetical protein 0.0498 0.1426 0.2415
Schistosoma mansoni scy1(yeast) protein kinase-like 0.0018 0.0001 0.0002
Echinococcus multilocularis gcn5proteinral control of amino acid synthesis 0.0307 0.0859 0.0859
Loa Loa (eye worm) BEN-1 protein 0.2007 0.5904 1
Schistosoma mansoni hypothetical protein 0.0065 0.014 0.0227
Trichomonas vaginalis conserved hypothetical protein 0.003 0.0036 0.0061
Echinococcus granulosus single minded 2 0.0039 0.0062 0.0102
Loa Loa (eye worm) papain family cysteine protease containing protein 0.002 0.0008 0.0007
Leishmania major beta tubulin 0.2007 0.5904 1
Trichomonas vaginalis tubulin gamma chain, putative 0.2007 0.5904 1
Echinococcus multilocularis tubulin, beta 4A class IVa 0.2007 0.5904 0.5904
Mycobacterium tuberculosis Putative ferredoxin reductase 0.0116 0.0291 0.2042
Echinococcus multilocularis Tubulin alpha 1 chain 0.1526 0.4477 0.4477
Mycobacterium ulcerans cytochrome P450 187A5 Cyp187A5 0.0019 0.0003 0.0024
Mycobacterium ulcerans cytochrome P450 105Q4 Cyp105Q4 0.0019 0.0003 0.0024
Toxoplasma gondii isocitrate dehydrogenase 0.0179 0.0481 0.0814
Echinococcus granulosus histone deacetylase 8 0.0299 0.0834 0.1357
Mycobacterium ulcerans cytochrome P450 123A3 Cyp123A3 0.0019 0.0003 0.0024
Brugia malayi histone deacetylase 11 0.0299 0.0834 0.1413
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.0152 0.04 0.065
Onchocerca volvulus 0.002 0.0008 0.003
Schistosoma mansoni chromobox protein 0.0075 0.017 0.0276
Mycobacterium ulcerans cytochrome P450 188A3 Cyp188A3 0.0019 0.0003 0.0024
Plasmodium vivax ATP-dependent Clp protease proteolytic subunit, putative 0.0094 0.0228 0.0386
Echinococcus multilocularis isocitrate dehydrogenase 0.0179 0.0481 0.0481
Schistosoma mansoni jumonji/arid domain-containing protein 0.0061 0.0129 0.0209
Trypanosoma brucei PAB1-binding protein , putative 0.0178 0.0477 0.0808
Schistosoma mansoni nuclear receptor 0.0067 0.0146 0.0238
Trichomonas vaginalis conserved hypothetical protein 0.0055 0.0111 0.0187
Loa Loa (eye worm) hypothetical protein 0.0026 0.0025 0.0037
Schistosoma mansoni serine/threonine protein kinase 0.0018 0.0001 0.0002
Echinococcus multilocularis smad 0.0092 0.0222 0.0222
Trypanosoma brucei unspecified product 0.0027 0.0029 0.005
Echinococcus granulosus tubulin epsilon chain 0.1147 0.3352 0.5452
Brugia malayi Pao retrotransposon peptidase family protein 0.0018 0.0001 0.0002
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.002 0.0008 0.0013
Trypanosoma brucei histone deacetylase 4 0.0409 0.1163 0.197
Schistosoma mansoni Tr4/Tr2 (homologue) 0.0152 0.04 0.065
Echinococcus multilocularis transfer RNA-Lys 0.0039 0.0062 0.0062
Echinococcus granulosus tubulin alpha chain 0.1526 0.4477 0.728
Echinococcus granulosus intermediate filament protein 0.0056 0.0114 0.0186
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0409 0.1161 0.1888
Mycobacterium tuberculosis Conserved protein 0.0039 0.0062 0.0438
Trypanosoma brucei trypanothione reductase 0.0051 0.0098 0.0167
Brugia malayi Cathepsin L-like precursor 0.002 0.0008 0.0013
Trypanosoma cruzi tubulin gamma chain 0.1147 0.3352 0.5678
Brugia malayi hypothetical protein 0.0018 0.0001 0.0002
Brugia malayi cytochrome P450 0.0019 0.0003 0.0006
Echinococcus granulosus u4:u6.u5 tri snrnp associated protein 2 0.0028 0.003 0.005
Brugia malayi RNase H family protein 0.0212 0.0578 0.098
Schistosoma mansoni alpha tubulin 0.1526 0.4477 0.728
Echinococcus multilocularis tubulin alpha 3 chain 0.1526 0.4477 0.4477
Toxoplasma gondii flap structure-specific endonuclease 1, putative 0.0028 0.0031 0.0052
Leishmania major aldehyde dehydrogenase, mitochondrial precursor 0.0062 0.0132 0.0224
Trichomonas vaginalis 6-phosphofructokinase, putative 0.0031 0.0041 0.007
Brugia malayi hypothetical protein 0.0115 0.0289 0.049
Echinococcus multilocularis tubulin epsilon chain 0.1147 0.3352 0.3352
Loa Loa (eye worm) hypothetical protein 0.0067 0.0146 0.0242
Echinococcus granulosus thioredoxin glutathione reductase 0.0051 0.0098 0.016
Onchocerca volvulus Rap guanine nucleotide exchange factor 1 homolog 0.0179 0.0479 0.2222
Echinococcus granulosus Tubulin beta 2C chain 0.2007 0.5904 0.9601
Mycobacterium ulcerans 6-phosphofructokinase 0.0117 0.0294 0.2061
Echinococcus granulosus Ataxin 2 N terminaldomain containing protein 0.008 0.0185 0.0301
Schistosoma mansoni TGF-beta signal transducer Smad2 0.0092 0.0222 0.0361
Mycobacterium tuberculosis Cell division protein FtsZ 0.0498 0.1426 1
Schistosoma mansoni smad1 5 8 and 0.0092 0.0222 0.0361
Loa Loa (eye worm) hypothetical protein 0.0152 0.04 0.0671
Plasmodium falciparum ataxin-2 like protein, putative 0.0178 0.0477 0.0808
Brugia malayi hypothetical protein 0.0018 0.0001 0.0002
Echinococcus granulosus GPCR family 2 0.0065 0.014 0.0227
Brugia malayi nuclear receptor subfamily 1, group D, member 1, putative 0.0067 0.0146 0.0248
Trypanosoma brucei DNA polymerase kappa, putative 0.0027 0.0029 0.005
Leishmania major cysteine peptidase A (CPA) 0.002 0.0008 0.0013
Toxoplasma gondii histone lysine acetyltransferase GCN5-A 0.0092 0.022 0.0372
Echinococcus granulosus peptidase Clp S14 family 0.0062 0.0132 0.0214
Mycobacterium leprae DIHYDROFOLATE REDUCTASE DFRA (DHFR) (TETRAHYDROFOLATE DEHYDROGENASE) 0.0047 0.0087 0.059
Echinococcus multilocularis chromobox protein 1 0.0075 0.017 0.017
Trichomonas vaginalis D-aminoacylase, putative 0.0039 0.0062 0.0106
Brugia malayi chromobox protein homolog 3 0.0042 0.0072 0.0122
Mycobacterium tuberculosis Probable cytochrome P450 monooxygenase 142 Cyp142 0.0019 0.0003 0.0024
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0077 0.0177 0.0299
Echinococcus multilocularis tubulin beta 1 chain 0.2007 0.5904 0.5904
Leishmania major beta tubulin 0.2007 0.5904 1
Chlamydia trachomatis fructose-6-phosphate phosphotransferase 0.0031 0.0041 0.1811
Brugia malayi MH2 domain containing protein 0.0092 0.0222 0.0376
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0028 0.003 0.0052
Mycobacterium tuberculosis Conserved hypothetical protein 0.0022 0.0012 0.0084
Plasmodium vivax histone deacetylase 2, putative 0.0409 0.1163 0.197
Leishmania major DNA polymerase kappa, putative 0.004 0.0066 0.0112
Brugia malayi mothers against decapentaplegic homolog 3 0.0041 0.007 0.0119
Leishmania major lanosterol 14-alpha-demethylase, putative 0.0019 0.0003 0.0006
Schistosoma mansoni dihydrofolate reductase 0.0047 0.0087 0.0142
Brugia malayi Hypothetical 29.7 kDa protein C05D11.5 in chromosome III 0.0022 0.0012 0.002
Trypanosoma cruzi hypothetical protein, conserved 0.0018 0.0001 0.0002
Echinococcus granulosus CREB binding protein 0.0018 0.0001 0.0001
Echinococcus granulosus cpg binding protein 0.0033 0.0044 0.0072
Echinococcus multilocularis telomerase reverse transcriptase subunit 0.0018 0.0001 0.0001
Loa Loa (eye worm) hypothetical protein 0.0204 0.0555 0.0934
Schistosoma mansoni hypothetical protein 0.0018 0.0001 0.0002
Trypanosoma brucei ATP-dependent 6-phosphofructokinase, glycosomal 0.0117 0.0294 0.0498
Echinococcus multilocularis isocitrate dehydrogenase 2 (NADP+) 0.0179 0.0481 0.0481
Trypanosoma cruzi dihydrofolate reductase-thymidylate synthase 0.0162 0.0429 0.0727
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0152 0.04 0.04
Giardia lamblia Reverse transcriptase/endonuclease, putative 0.0018 0.0001 0.0002
Echinococcus granulosus Smad4 0.0092 0.0222 0.0361
Schistosoma mansoni hypothetical protein 0.0065 0.014 0.0227
Loa Loa (eye worm) hypoxia-induced factor 1 0.0161 0.0427 0.0718
Toxoplasma gondii alpha tubulin TUBA1 0.1526 0.4477 0.7583
Echinococcus multilocularis neuropeptide receptor A26 0.05 0.1433 0.1433
Echinococcus granulosus NADP dependent isocitrate dehydrogenase 0.0179 0.0481 0.0782
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.019 0.0511 0.0831
Plasmodium falciparum ATP-dependent Clp protease proteolytic subunit 0.0033 0.0044 0.0075
Brugia malayi Thioredoxin reductase 0.0051 0.0098 0.0167
Trypanosoma brucei tubulin gamma chain 0.1147 0.3352 0.5678
Brugia malayi Nuclear hormone receptor family member nhr-1 0.0152 0.04 0.0677
Trichomonas vaginalis conserved hypothetical protein 0.0498 0.1426 0.2415
Echinococcus granulosus lamin 0.0056 0.0114 0.0186
Brugia malayi nuclear receptor RXR 0.0085 0.0201 0.0341
Echinococcus multilocularis Tubulin beta 2C chain 0.2007 0.5904 0.5904
Loa Loa (eye worm) ubiquitin carboxyl-terminal hydrolase 0.0028 0.003 0.0046
Mycobacterium tuberculosis Probable lipase LipD 0.0039 0.0062 0.0438
Trypanosoma brucei dihydrofolate reductase-thymidylate synthase 0.0162 0.0429 0.0727
Trichomonas vaginalis tubulin alpha-1 chain, putative 0.1028 0.2998 0.5079
Onchocerca volvulus Bile acid receptor homolog 0.0152 0.04 0.1851
Brugia malayi Cell division protein ftsZ 0.0498 0.1426 0.2415
Toxoplasma gondii UBA/TS-N domain-containing protein 0.0028 0.003 0.0052
Trichomonas vaginalis bromodomain-containing protein, putative 0.0092 0.022 0.0372
Leishmania major cathepsin L-like protease 0.002 0.0008 0.0013
Leishmania major cathepsin L-like protease 0.002 0.0008 0.0013
Leishmania major trypanothione reductase 0.0051 0.0098 0.0167
Brugia malayi Isocitrate dehydrogenase subunit gamma, mitochondrial precursor 0.0022 0.0013 0.0021
Schistosoma mansoni nuclear hormone receptor 0.0067 0.0146 0.0238
Echinococcus multilocularis jun protein 0.009 0.0215 0.0215
Mycobacterium tuberculosis Possible DNA-damage-inducible protein P DinP (DNA polymerase V) (pol IV 2) (DNA nucleotidyltransferase (DNA-directed)) 0.004 0.0066 0.0464
Echinococcus granulosus histone lysine methyltransferase setb 0.0064 0.0139 0.0226
Trypanosoma brucei DNA polymerase kappa, putative 0.004 0.0066 0.0112
Echinococcus multilocularis cathepsin l cysteine peptidase 0.002 0.0008 0.0008
Loa Loa (eye worm) tubulin beta-1 chain 0.2007 0.5904 1
Schistosoma mansoni histone deacetylase 1 2 3 0.0299 0.0834 0.1357
Trypanosoma cruzi histone deacetylase 1, putative 0.0928 0.2702 0.4577
Trichomonas vaginalis histone deacetylase 1, 2 ,3, putative 0.0928 0.2702 0.4577
Brugia malayi hypothetical protein 0.0055 0.0111 0.0187
Mycobacterium tuberculosis Cytochrome P450 121 Cyp121 0.0019 0.0003 0.0024
Loa Loa (eye worm) MH2 domain-containing protein 0.0041 0.007 0.0113
Echinococcus multilocularis mothers against decapentaplegic 2 0.0041 0.007 0.007
Brugia malayi Pre-SET motif family protein 0.0064 0.0139 0.0235
Echinococcus multilocularis terminal deoxycytidyl transferase rev1 0.004 0.0066 0.0066
Schistosoma mansoni hypothetical protein 0.2089 0.6149 1
Echinococcus multilocularis GPCR, family 2 0.0065 0.014 0.014
Trypanosoma cruzi ribonuclease H1, putative 0.0212 0.0578 0.098
Echinococcus multilocularis beta LACTamase domain containing family member 0.0039 0.0062 0.0062
Loa Loa (eye worm) isocitrate dehydrogenase 0.0179 0.0481 0.0809
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.002 0.0008 0.0013
Trypanosoma brucei DNA polymerase kappa, putative 0.004 0.0066 0.0112
Mycobacterium tuberculosis Probable conserved lipoprotein 0.0039 0.0062 0.0438
Loa Loa (eye worm) hypothetical protein 0.0152 0.04 0.0671
Loa Loa (eye worm) steroid hormone receptor 0.0152 0.04 0.0671
Echinococcus multilocularis tubulin alpha 0.1147 0.3352 0.3352
Giardia lamblia Reverse transcriptase/endonuclease 0.0018 0.0001 0.0002
Brugia malayi Pao retrotransposon peptidase family protein 0.0018 0.0001 0.0002
Echinococcus granulosus Transcription factor JmjC domain containing protein 0.0059 0.0123 0.0201
Trypanosoma brucei epsilon tubulin 0.1147 0.3352 0.5678
Toxoplasma gondii histone deacetylase HDAC4 0.0299 0.0834 0.1413
Trypanosoma brucei unspecified product 0.0027 0.0029 0.005
Mycobacterium tuberculosis Probable cytochrome P450 141 Cyp141 0.0019 0.0003 0.0024
Brugia malayi Pao retrotransposon peptidase family protein 0.0018 0.0001 0.0002
Schistosoma mansoni smad1 5 8 and 0.0092 0.0222 0.0361
Brugia malayi hypothetical protein 0.0018 0.0001 0.0002
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0028 0.003 0.0052
Loa Loa (eye worm) hypothetical protein 0.0051 0.01 0.0163
Trypanosoma cruzi histone deacetylase, putative 0.0299 0.0834 0.1413
Brugia malayi nuclear receptor NHR-67 0.0067 0.0146 0.0248
Trypanosoma brucei histone deacetylase, putative 0.0409 0.1163 0.197
Echinococcus multilocularis TGF beta signal transducer SmadC 0.0092 0.0222 0.0222
Schistosoma mansoni zinc finger protein 0.0067 0.0146 0.0238
Trypanosoma cruzi cysteine peptidase, putative 0.002 0.0008 0.0013
Leishmania major cytochrome p450-like protein 0.0019 0.0003 0.0006
Schistosoma mansoni cpg binding protein 0.0033 0.0044 0.0072
Echinococcus multilocularis aldehyde dehydrogenase, mitochondrial 0.0062 0.0132 0.0132
Trypanosoma brucei Zn-finger in ubiquitin-hydrolases and other protein, putative 0.0024 0.002 0.0033
Plasmodium falciparum AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0077 0.0176 0.0299
Plasmodium falciparum flap endonuclease 1 0.0028 0.0031 0.0052
Echinococcus multilocularis chromobox protein 1 0.0075 0.017 0.017
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0019 0.0005 0.0008
Trichomonas vaginalis histone deacetylase, putative 0.0928 0.2702 0.4577
Mycobacterium leprae PROBABLE ATP-DEPENDENT CLP PROTEASE PROTEOLYTIC SUBUNIT 2 CLPP2 (ENDOPEPTIDASE CLP 2) 0.0094 0.0228 0.1579
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0067 0.0146 0.0238
Plasmodium falciparum ATP-dependent 6-phosphofructokinase 0.0031 0.0041 0.007
Echinococcus granulosus RNA directed DNA polymerase reverse transcriptase 0.0018 0.0001 0.0002
Trypanosoma brucei alpha tubulin 0.1526 0.4477 0.7583
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.0152 0.04 0.0671
Giardia lamblia Pyrophosphate-fructose 6-phosphate 1-phosphotransferase alpha subunit 0.0031 0.0041 0.007
Toxoplasma gondii tubulin/FtsZ family, GTPase domain-containing protein 0.1147 0.3352 0.5678
Leishmania major beta tubulin 0.2007 0.5904 1
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0085 0.0201 0.0327
Brugia malayi Nuclear hormone receptor family member nhr-40 0.0152 0.04 0.0677
Echinococcus granulosus mothers against decapentaplegic 2 0.0041 0.007 0.0115
Trypanosoma brucei hypothetical protein, conserved 0.023 0.0632 0.107
Mycobacterium tuberculosis NADPH-dependent mycothiol reductase Mtr 0.0051 0.0098 0.069
Brugia malayi Dihydrofolate reductase 0.0047 0.0087 0.0148
Plasmodium vivax delta tubulin, putative 0.0498 0.1426 0.2415
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0067 0.0146 0.0146
Trypanosoma cruzi PAB1-binding protein , putative 0.0178 0.0477 0.0808
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.002 0.0008 0.0013
Leishmania major histone deacetylase, putative 0.0928 0.2702 0.4577
Loa Loa (eye worm) hypothetical protein 0.0135 0.0348 0.0584
Brugia malayi Cathepsin L-like precursor 0.002 0.0008 0.0013
Trichomonas vaginalis reverse transcriptases, putative 0.0018 0.0001 0.0002
Treponema pallidum cell division protein FtsZ 0.0498 0.1426 1
Brugia malayi Cathepsin L-like precursor 0.002 0.0008 0.0013
Loa Loa (eye worm) hypothetical protein 0.0152 0.04 0.0671
Echinococcus granulosus tubulin alpha chain 0.1526 0.4477 0.728
Trypanosoma brucei DNA polymerase IV, putative 0.004 0.0066 0.0112
Mycobacterium tuberculosis Conserved protein 0.0039 0.0062 0.0438
Echinococcus multilocularis histone deacetylase 3 0.0928 0.2702 0.2702
Toxoplasma gondii endonuclease IV APN 0.0082 0.0192 0.0325
Leishmania major cathepsin L-like protease 0.0077 0.0177 0.0299
Schistosoma mansoni bifunctional dihydrofolate reductase-thymidylate synthase 0.0115 0.029 0.0471
Mycobacterium leprae ATP-dependent Clp protease proteolytic subunit 1 0.0033 0.0044 0.0288
Toxoplasma gondii beta-1 tubulin, putative 0.2007 0.5904 1
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.002 0.0008 0.0013
Loa Loa (eye worm) hypothetical protein 0.0041 0.007 0.0113
Brugia malayi ImpB/MucB/SamB family protein 0.004 0.0066 0.0112
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.002 0.0008 0.0013
Echinococcus granulosus mothers against decapentaplegic 6 0.0041 0.007 0.0115
Leishmania major alpha tubulin 0.1526 0.4477 0.7583
Trypanosoma brucei isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0179 0.0481 0.0814
Echinococcus granulosus 6 phosphofructokinase 0.0117 0.0294 0.0478
Plasmodium falciparum ataxin-2 like protein, putative 0.0178 0.0477 0.0808
Brugia malayi Pao retrotransposon peptidase family protein 0.0018 0.0001 0.0002
Mycobacterium leprae conserved hypothetical protein 0.0022 0.0012 0.006
Trichomonas vaginalis DNA polymerase IV / kappa, putative 0.004 0.0066 0.0112
Mycobacterium leprae Probable lipase LipE 0.0039 0.0062 0.0415
Plasmodium falciparum alpha tubulin 2 0.1526 0.4477 0.7583
Toxoplasma gondii ribonuclease HI protein 0.0212 0.0578 0.098
Brugia malayi hypothetical protein 0.0071 0.0158 0.0267
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.0039 0.0062 0.0438
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0028 0.003 0.0052
Mycobacterium ulcerans hypothetical protein 0.0022 0.0012 0.0084
Trichomonas vaginalis tubulin beta chain, putative 0.1526 0.4477 0.7583
Trichomonas vaginalis tubulin gamma chain, putative 0.1147 0.3352 0.5678
Brugia malayi Heterochromatin protein 1 0.0075 0.017 0.0287
Schistosoma mansoni lamin 0.0056 0.0114 0.0186
Onchocerca volvulus Protein ultraspiracle homolog 0.0152 0.04 0.1851
Schistosoma mansoni hypothetical protein 0.0065 0.014 0.0227
Loa Loa (eye worm) tubulin alpha 2 0.1028 0.2998 0.5076
Entamoeba histolytica tubulin alpha-1 chain 0.1526 0.4477 0.7579
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0019 0.0005 0.0008
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0445 0.1268 0.2143
Trypanosoma brucei histone deacetylase 3 0.0409 0.1163 0.197
Loa Loa (eye worm) ubiquitin carboxyl-terminal hydrolase 0.0028 0.003 0.0046
Giardia lamblia Ubiquitin carboxyl-terminal hydrolase 14 0.0028 0.003 0.0052
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 22 0.0028 0.003 0.005
Echinococcus granulosus RNA directed DNA polymerase reverse transcriptase 0.0018 0.0001 0.0002
Trypanosoma cruzi alpha tubulin, putative 0.1526 0.4477 0.7583
Trypanosoma brucei ingi protein (ORF1) 0.023 0.0632 0.107
Mycobacterium ulcerans cytochrome p450 150 cyp150 0.0019 0.0003 0.0024
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0204 0.0555 0.0934
Echinococcus multilocularis ecdysone induced protein 78C 0.0152 0.04 0.04
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.002 0.0008 0.0013
Trypanosoma brucei DNA polymerase kappa, putative 0.004 0.0066 0.0112
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.0152 0.04 0.1851
Loa Loa (eye worm) tubulin alpha 2 0.1028 0.2998 0.5076
Trypanosoma brucei hypothetical protein, conserved 0.0039 0.0062 0.0106
Echinococcus multilocularis tubulin alpha 3 chain 0.1526 0.4477 0.4477
Mycobacterium ulcerans aldehyde dehydrogenase 0.0062 0.0132 0.0928
Loa Loa (eye worm) ubiquitin carboxyl-terminal hydrolase 0.0028 0.003 0.0046
Echinococcus granulosus cathepsin l1 0.002 0.0008 0.0013
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0077 0.0175 0.0285
Mycobacterium ulcerans sugar phosphate isomerases/epimerases 0.0022 0.0012 0.0084
Schistosoma mansoni nuclear hormone receptor 0.0067 0.0146 0.0238
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0028 0.003 0.0052
Plasmodium falciparum glutathione reductase 0.0051 0.0098 0.0167
Echinococcus granulosus geminin 0.2089 0.6149 1
Plasmodium vivax ataxin-2 like protein, putative 0.0178 0.0477 0.0808
Entamoeba histolytica phosphofructokinase, putative 0.0117 0.0294 0.0485
Loa Loa (eye worm) tubulin beta chain 0.0498 0.1426 0.2411
Schistosoma mansoni phosphoglucomutase 0.0212 0.0578 0.094
Schistosoma mansoni ubiquitin-specific peptidase 44 (C19 family) 0.0028 0.003 0.005
Brugia malayi thymidylate synthase 0.0115 0.029 0.0491
Mycobacterium tuberculosis Probable cytochrome P450 132 Cyp132 0.0019 0.0003 0.0024
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.002 0.0008 0.0013
Schistosoma mansoni retinoic acid receptor RXR 0.0258 0.0713 0.116
Echinococcus granulosus CREB binding protein 0.0116 0.0293 0.0476
Leishmania major ribonuclease H1, putative 0.0212 0.0578 0.098
Loa Loa (eye worm) histone deacetylase 7A 0.0409 0.1163 0.1965
Echinococcus granulosus tubulin alpha 3 chain 0.1526 0.4477 0.728
Loa Loa (eye worm) DR-78 0.0067 0.0146 0.0242
Brugia malayi isocitrate dehydrogenase 0.0179 0.0481 0.0814
Loa Loa (eye worm) hypothetical protein 0.0067 0.0146 0.0242
Leishmania major beta tubulin 0.2007 0.5904 1
Treponema pallidum diphosphate--fructose-6-phosphate 1-phosphotransferase 0.0031 0.0041 0.029
Trypanosoma cruzi cytochrome P450, putative 0.0028 0.0031 0.0053
Trypanosoma brucei DNA polymerase kappa, putative 0.0027 0.0029 0.005
Brugia malayi Tubulin alpha-2 chain 0.1526 0.4477 0.7583
Trichomonas vaginalis histone deacetylase, putative 0.0928 0.2702 0.4577
Plasmodium vivax tubulin alpha chain, putative 0.1526 0.4477 0.7583
Loa Loa (eye worm) Papain cysteine protease/cathepsin propeptide inhibitor-containing protein 0.002 0.0008 0.0007
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0204 0.0555 0.0939
Echinococcus granulosus tubulin gamma 1 chain 0.1147 0.3352 0.5452
Schistosoma mansoni hypothetical protein 0.2089 0.6149 1
Loa Loa (eye worm) nuclear hormone receptor-like 1 0.0085 0.0201 0.0335
Brugia malayi MH1 domain containing protein 0.0092 0.0222 0.0376
Schistosoma mansoni chromobox protein 0.0075 0.017 0.0276
Echinococcus granulosus tumor protein p63 0.0702 0.2032 0.3304
Trichomonas vaginalis phosphofructokinase, putative 0.0031 0.0041 0.007
Brugia malayi bZIP transcription factor family protein 0.009 0.0215 0.0364
Trypanosoma cruzi epsilon tubulin, putative 0.1147 0.3352 0.5678
Echinococcus multilocularis ribonuclease H1 0.0212 0.0578 0.0578
Echinococcus multilocularis histone deacetylase 6 0.0409 0.1163 0.1163
Echinococcus granulosus ecdysone induced protein 78C 0.0152 0.04 0.065
Mycobacterium tuberculosis Probable esterase LipL 0.0039 0.0062 0.0438
Echinococcus granulosus Basic leucine zipper bZIP transcription factor 0.009 0.0215 0.035
Brugia malayi MH2 domain containing protein 0.0092 0.0222 0.0376
Loa Loa (eye worm) tubulin alpha chain 0.1526 0.4477 0.7581
Trypanosoma cruzi major cysteine proteinase, putative 0.0061 0.0128 0.0216
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0028 0.003 0.0052
Loa Loa (eye worm) hypothetical protein 0.0085 0.0201 0.0335
Loa Loa (eye worm) hypothetical protein 0.0022 0.0013 0.0015
Trypanosoma brucei DNA polymerase kappa, putative 0.004 0.0066 0.0112
Loa Loa (eye worm) hypothetical protein 0.1028 0.2998 0.5076
Toxoplasma gondii histone lysine acetyltransferase GCN5-B 0.0092 0.022 0.0372
Mycobacterium ulcerans cytochrome P450 142A3 Cyp142A3 0.0019 0.0003 0.0024
Trypanosoma cruzi epsilon tubulin, putative 0.1147 0.3352 0.5678
Brugia malayi histone deacetylase 1 (HD1) 0.0928 0.2702 0.4577
Leishmania major beta tubulin 0.2007 0.5904 1
Brugia malayi MH1 domain containing protein 0.0051 0.01 0.0169
Mycobacterium tuberculosis Possible cytochrome P450 135A1 Cyp135A1 0.0019 0.0003 0.0024
Mycobacterium tuberculosis Probable cytochrome P450 125 Cyp125 0.0019 0.0003 0.0024
Trichomonas vaginalis tubulin beta chain, putative 0.0649 0.1874 0.3174
Schistosoma mansoni tubulin subunit alpha 0.1526 0.4477 0.728
Echinococcus multilocularis tumor protein p63 0.0702 0.2032 0.2032
Onchocerca volvulus 0.0067 0.0146 0.0673
Loa Loa (eye worm) hypothetical protein 0.0067 0.0146 0.0242
Trypanosoma brucei zeta tubulin 0.0498 0.1426 0.2415
Leishmania major histone deacetylase, putative 0.0928 0.2702 0.4577
Echinococcus multilocularis RNA directed DNA polymerase (reverse transcriptase) 0.0018 0.0001 0.0001
Loa Loa (eye worm) hypothetical protein 0.0065 0.014 0.0231
Onchocerca volvulus 0.0033 0.0045 0.0204
Trichomonas vaginalis ap endonuclease, putative 0.0077 0.0176 0.0299
Echinococcus granulosus tubulin beta 1 chain 0.2007 0.5904 0.9601
Trypanosoma brucei beta tubulin 0.2007 0.5904 1
Brugia malayi Pao retrotransposon peptidase family protein 0.0018 0.0001 0.0002
Echinococcus granulosus Nuclear hormone receptor HR96 0.0067 0.0146 0.0238
Schistosoma mansoni hypothetical protein 0.0019 0.0003 0.0006
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0077 0.0177 0.0299
Loa Loa (eye worm) nuclear receptor nhr-7B 0.0067 0.0146 0.0242
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.0152 0.04 0.0671
Leishmania major cathepsin L-like protease 0.002 0.0008 0.0013
Plasmodium vivax histone acetyltransferase GCN5, putative 0.0092 0.022 0.0372
Brugia malayi nuclear hormone receptor family member odr-7 0.0067 0.0146 0.0248
Trypanosoma cruzi histone deacetylase, putative 0.0409 0.1163 0.197
Brugia malayi hypothetical protein 0.0085 0.0201 0.0341
Trypanosoma brucei DNA polymerase eta, putative 0.004 0.0066 0.0112
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.0039 0.0062 0.0438
Brugia malayi Pao retrotransposon peptidase family protein 0.0018 0.0001 0.0002
Leishmania major cathepsin L-like protease 0.0077 0.0177 0.0299
Brugia malayi Histone deacetylase family protein 0.0409 0.1163 0.197
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0064 0.0139 0.0226
Trypanosoma cruzi cysteine peptidase, clan CA, family C1, cathepsin L-like, putative 0.007 0.0157 0.0265
Plasmodium vivax hypothetical protein, conserved 0.0024 0.002 0.0033
Brugia malayi hypothetical protein 0.03 0.0838 0.1419
Trypanosoma cruzi Lanosterol 14-alpha demethylase 0.0019 0.0003 0.0006
Brugia malayi reverse transcriptase 0.0018 0.0001 0.0002
Onchocerca volvulus Mothers against decapentaplegic homolog 0.0041 0.007 0.0321
Echinococcus granulosus tubulin subunit TubB 0.1526 0.4477 0.728
Treponema pallidum ribonuclease H (rnhA) 0.0212 0.0578 0.4055
Onchocerca volvulus 0.0056 0.0114 0.0524
Mycobacterium ulcerans dihydrofolate reductase DfrA 0.0047 0.0087 0.0612
Toxoplasma gondii histone lysine methyltransferase SET1 0.007 0.0156 0.0264
Mycobacterium tuberculosis Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) 0.0077 0.0176 0.1236
Onchocerca volvulus 0.002 0.0008 0.003
Trypanosoma cruzi ATP-dependent 6-phosphofructokinase, glycosomal 0.0117 0.0294 0.0498
Leishmania major cytochrome p450-like protein 0.0028 0.0031 0.0053
Schistosoma mansoni NADP-specific isocitrate dehydrogenase 0.0179 0.0481 0.0782
Mycobacterium ulcerans hypothetical protein 0.0039 0.0062 0.0438
Echinococcus multilocularis beta tubulin 0.2007 0.5904 0.5904
Brugia malayi CXXC zinc finger family protein 0.0031 0.0039 0.0067
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.002 0.0008 0.0013
Echinococcus granulosus histone acetyltransferase KAT2B 0.0092 0.022 0.0358
Mycobacterium tuberculosis Probable lipase LipE 0.0039 0.0062 0.0438
Loa Loa (eye worm) hypothetical protein 0.031 0.0869 0.1467
Brugia malayi Pao retrotransposon peptidase family protein 0.0018 0.0001 0.0002
Echinococcus multilocularis RNA directed DNA polymerase (reverse transcriptase) 0.0018 0.0001 0.0001
Echinococcus granulosus CREB binding protein 0.0018 0.0001 0.0001
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.0152 0.04 0.065
Schistosoma mansoni tubulin subunit beta 0.2007 0.5904 0.9601
Mycobacterium ulcerans epimerase 0.0022 0.0012 0.0084
Trichomonas vaginalis flap endonuclease-1, putative 0.0028 0.0031 0.0052
Mycobacterium ulcerans cytochrome P450 143A3 Cyp143A3 0.0019 0.0003 0.0024
Brugia malayi nuclear hormone receptor family member nhr-6 0.0067 0.0146 0.0248
Brugia malayi alpha-tubulin 0.1526 0.4477 0.7583
Loa Loa (eye worm) hypothetical protein 0.0055 0.0111 0.0182
Onchocerca volvulus Ribonuclease H1 homolog 0.0212 0.0578 0.2682
Mycobacterium tuberculosis NAD(P)H quinone reductase LpdA 0.0129 0.033 0.2311
Brugia malayi Cathepsin L-like precursor 0.002 0.0008 0.0013
Schistosoma mansoni ubiquitin-specific peptidase 5 (C19 family) 0.0028 0.003 0.005
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.0152 0.04 0.04
Echinococcus granulosus nuclear receptor nhr 48 0.0067 0.0146 0.0238
Trichomonas vaginalis chromobox protein, putative 0.0045 0.0082 0.0138
Echinococcus granulosus FTZ F1 alpha 0.0152 0.04 0.065
Onchocerca volvulus Cathepsin L homolog 0.002 0.0008 0.003
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0152 0.04 0.065
Brugia malayi isocitrate dehydrogenase [NAD] subunit alpha, mitochondrial 0.0022 0.0013 0.0021
Echinococcus multilocularis mothers against decapentaplegic 6 0.0041 0.007 0.007
Echinococcus granulosus RNA directed DNA polymerase reverse transcriptase 0.0018 0.0001 0.0002
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.002 0.0008 0.0013
Trichomonas vaginalis histone deacetylase, putative 0.0928 0.2702 0.4577
Brugia malayi Nuclear hormone receptor-like 1 0.0152 0.04 0.0677
Echinococcus granulosus alpha tubulin 0.1526 0.4477 0.728
Trichomonas vaginalis tubulin beta chain, putative 0.1526 0.4477 0.7583
Trichomonas vaginalis tubulin gamma chain, putative 0.1147 0.3352 0.5678
Mycobacterium ulcerans exodeoxyribonuclease III protein XthA 0.0077 0.0176 0.1236
Plasmodium falciparum tubulin gamma chain 0.1147 0.3352 0.5678
Schistosoma mansoni tubulin subunit beta 0.2007 0.5904 0.9601
Leishmania major alpha tubulin 0.1526 0.4477 0.7583
Onchocerca volvulus 0.002 0.0008 0.003
Trypanosoma cruzi histone deacetylase, putative 0.0409 0.1163 0.197
Plasmodium vivax isocitrate dehydrogenase [NADP], mitochondrial, putative 0.0179 0.0481 0.0814
Echinococcus granulosus Tubulin alpha 1 chain 0.1526 0.4477 0.728
Loa Loa (eye worm) hypothetical protein 0.0039 0.0062 0.01
Trichomonas vaginalis NeSL-1_NeSL reverse transcriptases, putative 0.0018 0.0001 0.0002
Mycobacterium tuberculosis Probable 6-phosphofructokinase PfkA (phosphohexokinase) (phosphofructokinase) 0.0117 0.0294 0.2061
Trichomonas vaginalis cat eye syndrome critical region protein 2, cscr2, putative 0.0092 0.022 0.0372
Echinococcus granulosus histone deacetylase 6 0.0409 0.1163 0.1891
Echinococcus granulosus tubulin alpha chain 0.1526 0.4477 0.728
Treponema pallidum ATP-dependent Clp protease proteolytic subunit 0.0033 0.0044 0.0311
Treponema pallidum exodeoxyribonuclease (exoA) 0.0077 0.0176 0.1236
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0019 0.0005 0.0008
Echinococcus granulosus histone deacetylase 0.0409 0.1163 0.1891
Brugia malayi hypothetical protein 0.0067 0.0146 0.0248
Echinococcus granulosus retinoic acid receptor rxr beta a 0.0258 0.0713 0.116
Loa Loa (eye worm) tubulin alpha chain 0.1526 0.4477 0.7581
Toxoplasma gondii phosphofructokinase PFKII 0.0031 0.0041 0.007
Brugia malayi reverse transcriptase 0.0018 0.0001 0.0002
Loa Loa (eye worm) jmjC domain-containing protein 0.0061 0.0129 0.0212
Mycobacterium leprae conserved hypothetical protein 0.0039 0.0062 0.0415
Mycobacterium leprae PROBABLE ATP-DEPENDENT CLP PROTEASE PROTEOLYTIC SUBUNIT 1 CLPP1 (ENDOPEPTIDASE CLP) 0.0062 0.0132 0.0901
Brugia malayi Zinc knuckle family protein 0.0018 0.0001 0.0002
Schistosoma mansoni Isocitrate dehydrogenase [NAD] subunit gamma mitochondrial 0.0022 0.0013 0.002
Echinococcus multilocularis tubulin alpha chain 0.1526 0.4477 0.4477
Echinococcus granulosus histone deacetylase 6 0.0409 0.1163 0.1891
Schistosoma mansoni histone deacetylase hda2 0.0434 0.1235 0.2008
Brugia malayi Probable isocitrate dehydrogenase 0.0022 0.0013 0.0021
Echinococcus multilocularis peroxisome assembly protein 26 0.1526 0.4477 0.4477
Mycobacterium ulcerans cytochrome P450 126A3 Cyp126A3 0.0019 0.0003 0.0024
Brugia malayi Histone deacetylase family protein 0.0409 0.1163 0.197
Schistosoma mansoni tubulin subunit alpha 0.1526 0.4477 0.728
Echinococcus multilocularis FTZ F1 alpha 0.0152 0.04 0.04
Leishmania major beta tubulin 0.2007 0.5904 1
Plasmodium vivax 6-phosphofructokinase, putative 0.0031 0.0041 0.007
Entamoeba histolytica Sir2 family transcriptional regulator, putative 0.0024 0.002 0.002
Trichomonas vaginalis tubulin epsilon chain, putative 0.1526 0.4477 0.7583
Schistosoma mansoni microtubule-associated protein tau 0.0833 0.2421 0.3938
Mycobacterium ulcerans esterase/lipase LipP 0.0039 0.0062 0.0438
Trypanosoma brucei beta tubulin 0.1147 0.3352 0.5678
Echinococcus multilocularis RNA directed DNA polymerase (reverse transcriptase) 0.0018 0.0001 0.0001
Echinococcus multilocularis muscleblind protein 1 0.031 0.0869 0.0869
Echinococcus granulosus flap endonuclease 1 0.0028 0.0031 0.005
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.002 0.0008 0.0013
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0067 0.0146 0.0146
Leishmania major alpha tubulin 0.1526 0.4477 0.7583
Loa Loa (eye worm) hypothetical protein 0.0085 0.0201 0.0335
Echinococcus multilocularis lamin dm0 0.0056 0.0114 0.0114
Toxoplasma gondii hypothetical protein 0.0033 0.0044 0.0075

Activities

Activity type Activity value Assay description Source Reference
Potency (functional) = 0.631 um PUBCHEM_BIOASSAY: qHTS Screen for Compounds that Selectively Target Cancer Cells with p53 Mutations: Cytotoxicity of p53ts Cells at the Nonpermissive Temperature. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) 2.2387 uM PUBCHEM_BIOASSAY: qHTS for Inhibitors of TGF-b. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID588856, AID588860] ChEMBL. No reference
Potency (functional) = 7.9433 um PUBCHEM_BIOASSAY: Counterscreen qHTS for Inhibitors of Tau Fibril Formation, Fluorescence Polarization. This assay monitors tau fibrillation by fluorescence polarization (FP) of Alexa 594-labeled K18 P301L, which does not fibrillize readily but incorporates into growing filaments of unlabeled tau. (Class of assay: confirmatory) [Related pubchem assays: 596 ] ChEMBL. No reference
Potency (functional) = 12.5893 um PUBCHEM_BIOASSAY: qHTS Assay for Promiscuous and Specific Inhibitors of Cruzain (without detergent). (Class of assay: confirmatory) [Related pubchem assays: 2158 (Confirmation qHTS Assay for Inhibitors of Cruzain), 2249 (Probe Development Summary of Promiscuous Inhibitors (Artifacts) of Cruzain), 2161 (qHTS Assay for Inhibitors of Papain: Counterscreen for Cruzain Assay), 1478 (qHTS Assay for Promiscuous and Specific Inhibitors of Cruzain (with detergent))] ChEMBL. No reference
Potency (functional) 16.3601 uM PUBCHEM_BIOASSAY: Nrf2 qHTS screen for inhibitors. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID493153, AID493163, AID504648] ChEMBL. No reference

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

No literature references available for this target.

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