Detailed information for compound 1290478

Basic information

Technical information
  • TDR Targets ID: 1290478
  • Name: tetrasodium [(2S,3S,4R,5S)-2-(6-aminopurin-9- yl)-5-[[[[(2S,3R,4S,5R)-5-(3-carbamoyl-4H-pyr idin-1-yl)-3,4-dihydroxyoxolan-2-yl]methoxy-o xidophosphoryl]oxy-oxidophosphoryl]oxymethyl] -4-hydroxyoxolan-3-yl] phosphate
  • MW: 833.348 | Formula: C21H26N7Na4O17P3
  • H donors: 9 H acceptors: 14 LogP: -6.87 Rotable bonds: 13
    Rule of 5 violations (Lipinski): 3
  • SMILES: O[C@H]1[C@@H](O)[C@@H](O[C@H]1N1C=CCC(=C1)C(=O)N)COP(=O)(OP(=O)(OC[C@@H]1O[C@@H]([C@H]([C@@H]1O)OP(=O)([O-])[O-])n1cnc2c1ncnc2N)[O-])[O-].[Na+].[Na+].[Na+].[Na+]
  • InChi: 1S/C21H30N7O17P3.4Na/c22-17-12-19(25-7-24-17)28(8-26-12)21-16(44-46(33,34)35)14(30)11(43-21)6-41-48(38,39)45-47(36,37)40-5-10-13(29)15(31)20(42-10)27-3-1-2-9(4-27)18(23)32;;;;/h1,3-4,7-8,10-11,13-16,20-21,29-31H,2,5-6H2,(H2,23,32)(H,36,37)(H,38,39)(H2,22,24,25)(H2,33,34,35);;;;/q;4*+1/p-4/t10-,11-,13-,14+,15-,16-,20+,21-;;;;/m0..../s1
  • InChiKey: WYWWVJHQDVCHKF-PFHUQVSOSA-J  


Substructure search Similarity search

Network

Hover on a compound node to display the structore

Synonyms

  • tetrasodium [(2S,3S,4R,5S)-2-(6-aminopurin-9-yl)-5-[[[[(2S,3R,4S,5R)-5-(3-carbamoyl-4H-pyridin-1-yl)-3,4-dihydroxy-tetrahydrofuran-2-yl]methoxy-oxido-phosphoryl]oxy-oxido-phosphoryl]oxymethyl]-4-hydroxy-tetrahydrofuran-3-yl] phosphate
  • tetrasodium [(2S,3S,4R,5S)-2-(6-amino-9-purinyl)-5-[[[[(2S,3R,4S,5R)-5-(3-carbamoyl-4H-pyridin-1-yl)-3,4-dihydroxy-2-tetrahydrofuranyl]methoxy-oxidophosphoryl]oxy-oxidophosphoryl]oxymethyl]-4-hydroxy-3-tetrahydrofuranyl] phosphate
  • tetrasodium [(2S,3S,4R,5S)-5-[[[[(2S,3R,4S,5R)-5-(3-aminocarbonyl-4H-pyridin-1-yl)-3,4-dihydroxy-oxolan-2-yl]methoxy-oxido-phosphoryl]oxy-oxido-phosphoryl]oxymethyl]-2-(6-aminopurin-9-yl)-4-hydroxy-oxolan-3-yl] phosphate
  • NCGC00016180-01
  • Lopac-N-7505

Targets

Known targets for this compound

Species Target name Source Bibliographic reference
Homo sapiens arachidonate 12-lipoxygenase Starlite/ChEMBL No references
Homo sapiens tumor protein p53 Starlite/ChEMBL No references
Homo sapiens thyroid stimulating hormone receptor Starlite/ChEMBL No references
Rattus norvegicus Muscarinic acetylcholine receptor M1 Starlite/ChEMBL No references

Predicted pathogen targets for this compound

By orthology
Species Potential target Known druggable target/s Ortholog Group
Loa Loa (eye worm) follicle stimulating hormone receptor Get druggable targets OG5_130089 All targets in OG5_130089
Echinococcus multilocularis tumor protein p63 Get druggable targets OG5_140038 All targets in OG5_140038
Echinococcus granulosus tumor protein p63 Get druggable targets OG5_140038 All targets in OG5_140038
Brugia malayi follicle stimulating hormone receptor Get druggable targets OG5_130089 All targets in OG5_130089
By sequence similarity to non orthologous known druggable targets
Species Potential target Known druggable target Length Alignment span Identity
Echinococcus multilocularis serotonin receptor Muscarinic acetylcholine receptor M1   460 aa 432 aa 26.6 %
Loa Loa (eye worm) hypothetical protein Muscarinic acetylcholine receptor M1   460 aa 425 aa 22.1 %
Echinococcus granulosus biogenic amine 5HT receptor Muscarinic acetylcholine receptor M1   460 aa 432 aa 26.6 %
Schistosoma japonicum ko:K04136 adrenergic receptor, alpha 1b, putative Muscarinic acetylcholine receptor M1   460 aa 462 aa 23.4 %
Echinococcus granulosus arachidonate 5 lipoxygenase arachidonate 12-lipoxygenase 663 aa 662 aa 22.8 %
Schistosoma mansoni amine GPCR Muscarinic acetylcholine receptor M1   460 aa 463 aa 27.0 %
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Trichomonas vaginalis set domain proteins, putative 0.0286 0.1656 0.5932
Trichomonas vaginalis PIKK family atypical protein kinase 0.0115 0.0607 0.2117
Echinococcus multilocularis axis inhibition protein axin 0.0023 0.0046 0.0046
Onchocerca volvulus Heterochromatin protein 1 homolog 0.0047 0.0193 0.0855
Trichomonas vaginalis conserved hypothetical protein 0.0021 0.0032 0.0027
Plasmodium vivax dihydroorotate dehydrogenase, mitochondrial precursor, putative 0.1187 0.7176 1
Leishmania major heat shock protein 83-1 0.021 0.1193 0.165
Brugia malayi CHE-14 protein 0.0044 0.0171 0.0224
Leishmania major phosphatidylinositol 4-kinase alpha, putative 0.0022 0.0039 0.004
Brugia malayi hypothetical protein 0.0315 0.1835 0.2546
Loa Loa (eye worm) CYP4Cod1 0.003 0.0088 0.0249
Echinococcus multilocularis geminin 0.0165 0.0916 0.0916
Trypanosoma brucei heat shock protein 84, putative 0.0086 0.0432 0.0569
Trichomonas vaginalis dihydroorotate dehydrogenase, putative 0.0469 0.2775 1
Echinococcus granulosus rhodopsin orphan GPCR 0.0315 0.1835 0.1835
Echinococcus multilocularis neuropeptide receptor 0.0315 0.1835 0.1835
Echinococcus multilocularis serotonin receptor 0.0315 0.1835 0.1835
Loa Loa (eye worm) TYRA-2 protein 0.0315 0.1835 0.5188
Echinococcus granulosus serotonin receptor 0.0315 0.1835 0.1835
Entamoeba histolytica protein kinase rad3, putative 0.0065 0.03 0.0955
Loa Loa (eye worm) phosphatidylinositol 3 0.0022 0.0039 0.011
Trypanosoma brucei DNA topoisomerase II beta, putative 0.0043 0.0166 0.0198
Brugia malayi Cytochrome P450 family protein 0.002 0.0027 0.0023
Brugia malayi Cytochrome P450 family protein 0.003 0.0088 0.0108
Echinococcus multilocularis phosphatidylinositol 4,5 bisphosphate 3 kinase 0.0022 0.0039 0.0039
Brugia malayi A-kinase anchor protein 10, precursor 0.0023 0.0046 0.0049
Echinococcus multilocularis Pyruvate dehydrogenase (lipoamide) kinase 0.0043 0.0166 0.0166
Brugia malayi phosphatidylinositol 4-kinase, catalytic, alpha polypeptide 0.0022 0.0039 0.004
Echinococcus granulosus cytochrome P450 2K1 0.002 0.0027 0.0027
Trypanosoma cruzi phosphatidylinositol 4-kinase alpha, putative 0.0022 0.0039 0.002
Echinococcus multilocularis FTZ F1 alpha 0.0028 0.0072 0.0072
Echinococcus multilocularis phosphatidylinositol 4 kinase alpha 0.0022 0.0039 0.0039
Echinococcus granulosus Regulator of G protein signaling 20 0.0023 0.0046 0.0046
Leishmania major target of rapamycin (TOR) kinase 2, putative 0.0115 0.0607 0.0833
Mycobacterium tuberculosis Two component sensor histidine kinase TrcS 0.0043 0.0166 0.0198
Brugia malayi Bromodomain containing protein 0.0029 0.0083 0.0101
Trichomonas vaginalis cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0029 0.0082 0.0207
Echinococcus multilocularis FKBP12 rapamycin complex associated protein 0.0115 0.0607 0.0607
Loa Loa (eye worm) voltage and ligand gated potassium channel 0.0036 0.0122 0.0345
Entamoeba histolytica hypothetical protein 0.0072 0.0347 0.1127
Leishmania major phosphatidylinositol 3-related kinase, putative 0.0115 0.0607 0.0833
Brugia malayi hypothetical protein 0.0315 0.1835 0.2546
Echinococcus granulosus ecdysone induced protein 78C 0.0028 0.0072 0.0072
Schistosoma mansoni hypothetical protein 0.0165 0.0916 0.1247
Loa Loa (eye worm) Pin1-type peptidyl-prolyl cis-trans isomerase 0.004 0.0151 0.0426
Echinococcus multilocularis serine protein kinase ATM 0.0065 0.03 0.03
Mycobacterium ulcerans cytochrome P450 126A3 Cyp126A3 0.002 0.0027 0.0003
Leishmania major heat shock protein 83-1 0.021 0.1193 0.165
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0036 0.0125 0.0139
Mycobacterium ulcerans long-chain fatty-acid CoA ligase 0.0048 0.0196 0.0239
Echinococcus multilocularis neuropeptide s receptor 0.0315 0.1835 0.1835
Onchocerca volvulus Heterochromatin protein 1 homolog 0.0051 0.0215 0.0978
Echinococcus multilocularis heat shock protein 0.021 0.1193 0.1193
Trypanosoma cruzi heat shock protein 85, putative 0.021 0.1193 0.1633
Echinococcus granulosus allatostatin A receptor 0.0315 0.1835 0.1835
Trypanosoma brucei heat shock protein, putative 0.021 0.1193 0.1633
Schistosoma mansoni biogenic amine receptor 0.0315 0.1835 0.2531
Trichomonas vaginalis conserved hypothetical protein 0.004 0.0151 0.0458
Echinococcus multilocularis heat shock protein 75 kDa, mitochondrial 0.0086 0.0432 0.0432
Mycobacterium tuberculosis Conserved protein 0.0043 0.0166 0.0198
Echinococcus granulosus rhodopsin orphan GPCR 0.0315 0.1835 0.1835
Onchocerca volvulus 0.0037 0.013 0.0508
Trypanosoma cruzi heat shock protein 85, putative 0.0168 0.093 0.1266
Plasmodium falciparum LCCL domain-containing protein 0.0024 0.005 0.0034
Onchocerca volvulus Protein ultraspiracle homolog 0.0028 0.0072 0.0186
Schistosoma mansoni thyrotropin-releasing hormone receptor 0.0315 0.1835 0.2531
Entamoeba histolytica hypothetical protein 0.0023 0.0046 0.0024
Echinococcus multilocularis allatostatin A receptor 0.0315 0.1835 0.1835
Echinococcus multilocularis rhodopsin orphan GPCR 0.0315 0.1835 0.1835
Echinococcus granulosus phosphatidylinositol 4 kinase alpha 0.0022 0.0039 0.0039
Loa Loa (eye worm) hypothetical protein 0.0023 0.0046 0.0129
Echinococcus multilocularis neuropeptide Y receptor 0.0315 0.1835 0.1835
Loa Loa (eye worm) hypothetical protein 0.0047 0.0193 0.0545
Schistosoma mansoni nuclear hormone receptor 0.0028 0.0072 0.0066
Trichomonas vaginalis conserved hypothetical protein 0.0021 0.0032 0.0027
Echinococcus granulosus serine protein kinase ATM 0.0065 0.03 0.03
Onchocerca volvulus 0.0315 0.1835 1
Plasmodium falciparum thioredoxin reductase 0.0057 0.0254 0.032
Mycobacterium tuberculosis Cytochrome P450 121 Cyp121 0.002 0.0027 0.0003
Schistosoma mansoni pyruvate dehydrogenase 0.0043 0.0166 0.0198
Wolbachia endosymbiont of Brugia malayi membrane associated signal transduction histidine kinase 0.0043 0.0166 0.0198
Mycobacterium ulcerans two component system membrane associated sensor kinase 0.0043 0.0166 0.0198
Mycobacterium tuberculosis Probable cytochrome P450 141 Cyp141 0.002 0.0027 0.0003
Brugia malayi Pre-SET motif family protein 0.0251 0.1444 0.2
Echinococcus granulosus heat shock protein 75 kDa mitochondrial 0.0086 0.0432 0.0432
Loa Loa (eye worm) G-protein coupled receptor 0.0315 0.1835 0.5188
Echinococcus granulosus growth hormone secretagogue receptor type 1 0.0315 0.1835 0.1835
Giardia lamblia Phosphatidylinositol 4-kinase 0.0022 0.0039 0.0121
Schistosoma mansoni camp/cgmp cyclic nucleotide phosphodiesterase 0.0029 0.0082 0.008
Brugia malayi neuropeptide F receptor 0.0315 0.1835 0.2546
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0028 0.0072 0.0072
Trichomonas vaginalis conserved hypothetical protein 0.0021 0.0032 0.0027
Echinococcus granulosus sex peptide receptor 0.0315 0.1835 0.1835
Plasmodium falciparum phosphatidylinositol 3- and 4-kinase, putative 0.0022 0.0039 0.002
Echinococcus granulosus PHD finger protein rhinoceros 0.0029 0.0083 0.0083
Plasmodium vivax phosphatidylinositol 3-kinase, putative 0.0022 0.0039 0.002
Echinococcus multilocularis orexin receptor type 2 0.0315 0.1835 0.1835
Echinococcus granulosus alpha 1A adrenergic receptor 0.0315 0.1835 0.1835
Trichomonas vaginalis PIKK family atypical protein kinase 0.0115 0.0607 0.2117
Echinococcus multilocularis PHD finger protein rhinoceros 0.0029 0.0083 0.0083
Loa Loa (eye worm) hypothetical protein 0.0315 0.1835 0.5188
Toxoplasma gondii cytochrome p450 superfamily protein 0.002 0.0027 0.0003
Loa Loa (eye worm) hypothetical protein 0.0048 0.0196 0.0553
Loa Loa (eye worm) hypothetical protein 0.0315 0.1835 0.5188
Trichomonas vaginalis dihydroorotate dehydrogenase, putative 0.0463 0.2743 0.9883
Leishmania major phosphatidylinositol 3-kinase, putative 0.0022 0.0039 0.004
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD3 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0034 0.011 0.0119
Schistosoma mansoni hypothetical protein 0.005 0.021 0.0259
Loa Loa (eye worm) G protein signaling regulator EGL-10 0.0023 0.0046 0.0129
Schistosoma mansoni hypothetical protein 0.0024 0.005 0.0034
Schistosoma mansoni peptide (allatostatin/somatostatin)-like receptor 0.0315 0.1835 0.2531
Trypanosoma brucei phosphatidylinositol 3-kinase catalytic subunit, putative 0.0022 0.0039 0.002
Brugia malayi sulfakinin receptor protein 0.0315 0.1835 0.2546
Trichomonas vaginalis PIKK family atypical protein kinase 0.0065 0.03 0.1002
Trichomonas vaginalis heat shock protein, putative 0.021 0.1193 0.4245
Mycobacterium ulcerans cytochrome P450 105Q4 Cyp105Q4 0.002 0.0027 0.0003
Brugia malayi neuropeptide F receptor 0.0315 0.1835 0.2546
Trichomonas vaginalis cAMP-specific 3,5-cyclic phosphodiesterase, putative 0.0029 0.0082 0.0207
Schistosoma mansoni opsin-like receptor 0.0315 0.1835 0.2531
Schistosoma mansoni hypothetical protein 0.0315 0.1835 0.2531
Loa Loa (eye worm) hypothetical protein 0.0036 0.0122 0.0344
Leishmania major phosphatidylinositol kinase related protein, putative 0.0022 0.0039 0.004
Brugia malayi Intermediate filament tail domain containing protein 0.0033 0.0103 0.0129
Brugia malayi DNA topoisomerase II, alpha isozyme 0.0043 0.0166 0.0217
Toxoplasma gondii DNA topoisomerase 2, putative 0.0043 0.0166 0.0198
Echinococcus granulosus neuropeptides capa receptor 0.0315 0.1835 0.1835
Schistosoma mansoni survival motor neuron protein 0.005 0.0209 0.0258
Brugia malayi Regulator of G protein signaling domain containing protein 0.0023 0.0046 0.0049
Leishmania major heat shock protein 83-1 0.021 0.1193 0.165
Brugia malayi glutathione reductase 0.0057 0.0254 0.0339
Trypanosoma cruzi trypanothione reductase, putative 0.0057 0.0254 0.032
Schistosoma mansoni lipoxygenase 0.0067 0.0312 0.0402
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD5 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0034 0.011 0.0119
Echinococcus multilocularis fmrfamide receptor 0.0315 0.1835 0.1835
Schistosoma mansoni hypothetical protein 0.0165 0.0916 0.1247
Loa Loa (eye worm) endoplasmin 0.021 0.1193 0.3372
Leishmania major heat shock protein 83-1 0.021 0.1193 0.165
Brugia malayi 3'5'-cyclic nucleotide phosphodiesterase family protein 0.0029 0.0082 0.01
Trichomonas vaginalis conserved hypothetical protein 0.0047 0.0193 0.061
Brugia malayi PAS domain containing protein 0.0049 0.0203 0.0269
Echinococcus granulosus rhodopsin orphan GPCR 0.0315 0.1835 0.1835
Plasmodium vivax hypothetical protein, conserved 0.0021 0.0032 0.001
Leishmania major heat shock protein 83-1 0.021 0.1193 0.165
Schistosoma mansoni regulator of G protein signaling 0.0023 0.0046 0.0029
Toxoplasma gondii ATPase/histidine kinase/DNA gyrase B/HSP90 domain-containing protein 0.0043 0.0166 0.0198
Schistosoma mansoni neuropeptide receptor 0.0315 0.1835 0.2531
Schistosoma mansoni heat shock protein 0.021 0.1193 0.1633
Loa Loa (eye worm) hypothetical protein 0.0032 0.01 0.0282
Loa Loa (eye worm) hypothetical protein 0.0028 0.0072 0.0205
Echinococcus multilocularis rhodopsin orphan GPCR 0.0315 0.1835 0.1835
Trypanosoma cruzi phosphatidylinositol kinase related protein, putative 0.0022 0.0039 0.002
Chlamydia trachomatis DNA gyrase subunit B 0.0043 0.0166 0.6447
Trypanosoma brucei phosphatidylinositol 3-related kinase, putative 0.0115 0.0607 0.0814
Leishmania major hypothetical protein, unknown function 0.0022 0.0039 0.004
Brugia malayi Dopamine receptor protein 2 0.0315 0.1835 0.2546
Brugia malayi Dihydroorotate dehydrogenase, mitochondrial precursor, putative 0.1187 0.7176 1
Trypanosoma cruzi Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase, putative 0.0043 0.0166 0.0198
Echinococcus multilocularis regulator of G protein signaling 7 0.0023 0.0046 0.0046
Echinococcus multilocularis chromobox protein 1 0.0084 0.0419 0.0419
Mycobacterium tuberculosis Two component sensory transduction histidine kinase MtrB 0.0043 0.0166 0.0198
Entamoeba histolytica heat shock protein 90, putative 0.021 0.1193 0.4215
Echinococcus multilocularis heat shock protein 90 0.021 0.1193 0.1193
Trichomonas vaginalis receptor histidine kinase, putative 0.0043 0.0166 0.0514
Brugia malayi G protein-coupled receptor F59B2.13 0.0315 0.1835 0.2546
Brugia malayi Probable DNA topoisomerase II 0.0043 0.0166 0.0217
Echinococcus granulosus dual 3'5' cyclic AMP and GMP phosphodiesterase 0.0029 0.0082 0.0082
Mycobacterium ulcerans cytochrome P450 185A4 Cyp185A4 0.003 0.0088 0.0088
Mycobacterium tuberculosis NADPH-dependent mycothiol reductase Mtr 0.0057 0.0254 0.032
Echinococcus granulosus tm gpcr rhodopsin 0.0315 0.1835 0.1835
Trypanosoma cruzi cAMP specific phosphodiesterase, putative 0.0029 0.0082 0.008
Schistosoma mansoni single-minded 0.0049 0.0203 0.0249
Plasmodium vivax acyl-CoA synthetase, putative 0.0036 0.0122 0.0135
Loa Loa (eye worm) latrophilin receptor protein 2 0.0047 0.0192 0.0544
Mycobacterium tuberculosis Two component sensor kinase MprB 0.0043 0.0166 0.0198
Echinococcus granulosus rhodopsin orphan GPCR 0.0315 0.1835 0.1835
Mycobacterium ulcerans two component sensor histidine kinase DevS 0.0064 0.0295 0.0377
Brugia malayi Heterochromatin protein 1 0.0084 0.0419 0.057
Loa Loa (eye worm) phosphatidylinositol 3 0.0115 0.0607 0.1716
Brugia malayi Phospholipase A2 family protein 0.0101 0.0521 0.0713
Trichomonas vaginalis conserved hypothetical protein 0.0072 0.0346 0.1166
Loa Loa (eye worm) hypothetical protein 0.0152 0.0838 0.2369
Echinococcus granulosus Niemann Pick C1 protein 0.0102 0.0527 0.0527
Echinococcus granulosus dihydropyrimidine dehydrogenase NADP 0.0469 0.2775 0.2775
Toxoplasma gondii heat shock protein 90, putative 0.021 0.1193 0.1633
Schistosoma mansoni rab6-interacting 0.0024 0.005 0.0034
Giardia lamblia Heat shock protein HSP 90-alpha 0.0168 0.093 0.7752
Loa Loa (eye worm) phosphatidylinositol 3 0.0022 0.0039 0.011
Echinococcus multilocularis expressed protein 0.0451 0.2666 0.2666
Mycobacterium tuberculosis Probable cytochrome P450 132 Cyp132 0.002 0.0027 0.0003
Schistosoma mansoni biogenic amine receptor 0.0315 0.1835 0.2531
Brugia malayi Endoplasmin precursor 0.021 0.1193 0.165
Echinococcus multilocularis Niemann Pick C1 protein 0.0102 0.0527 0.0527
Echinococcus multilocularis Pyruvate dehydrogenase (lipoamide) kinase 0.0043 0.0166 0.0166
Echinococcus multilocularis G-protein coupled receptor, putative 0.0315 0.1835 0.1835
Schistosoma mansoni hypothetical protein 0.0047 0.0192 0.0234
Trichomonas vaginalis conserved hypothetical protein 0.0029 0.0082 0.0207
Trichomonas vaginalis sensory transduction histidine kinase bacterial, putative 0.0043 0.0166 0.0514
Echinococcus multilocularis lysine specific demethylase 5A 0.0035 0.0121 0.0121
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0315 0.1835 0.1835
Loa Loa (eye worm) phosphatidylinositol 3 0.0115 0.0607 0.1716
Echinococcus granulosus thyrotropin releasing hormone receptor 0.0315 0.1835 0.1835
Loa Loa (eye worm) 5-hydroxytryptamine 2C receptor 0.0315 0.1835 0.5188
Schistosoma mansoni DNA topoisomerase II 0.0043 0.0166 0.0198
Trichomonas vaginalis PIKK family atypical protein kinase 0.0115 0.0607 0.2117
Leishmania major acetoin dehydrogenase e3 component-like protein 0.002 0.0025 0.002
Trichomonas vaginalis dihydropyrimidine dehydrogenase, putative 0.0463 0.2743 0.9883
Brugia malayi hypoxia-induced factor 1 0.0151 0.0831 0.1145
Trichomonas vaginalis phosphatidylinositol 3-kinase catalytic subunit gamma, putative 0.0022 0.0039 0.0051
Brugia malayi Nuclear hormone receptor family member nhr-14 0.0028 0.0072 0.0086
Trichomonas vaginalis PIKK family atypical protein kinase 0.0115 0.0607 0.2117
Trypanosoma cruzi DNA topoisomerase II, putative 0.0043 0.0166 0.0198
Plasmodium vivax DNA topoisomerase II, putative 0.0043 0.0166 0.0198
Onchocerca volvulus 0.0315 0.1835 1
Toxoplasma gondii phosphatidylinositol 3- and 4-kinase 0.0022 0.0039 0.002
Entamoeba histolytica acyl-CoA synthetase, putative 0.0048 0.0196 0.0572
Brugia malayi PXA domain containing protein 0.0023 0.0046 0.0049
Trichomonas vaginalis chromobox protein, putative 0.0051 0.0215 0.069
Trichomonas vaginalis heat shock protein, putative 0.0086 0.0432 0.1479
Schistosoma mansoni aryl hydrocarbon receptor 0.0049 0.0203 0.0249
Trichomonas vaginalis cAMP-specific phosphodiesterase, putative 0.0029 0.0082 0.0207
Toxoplasma gondii phosphatidylinositol 3- and 4-kinase 0.0022 0.0039 0.002
Giardia lamblia GTOR 0.0115 0.0607 0.4986
Trichomonas vaginalis PIKK family atypical protein kinase 0.0115 0.0607 0.2117
Echinococcus granulosus g protein coupled receptor 0.0315 0.1835 0.1835
Echinococcus granulosus endoplasmin 0.0168 0.093 0.093
Brugia malayi AKH receptor 0.0315 0.1835 0.2546
Loa Loa (eye worm) hypothetical protein 0.0315 0.1835 0.5188
Mycobacterium ulcerans cytochrome P450 51B1 Cyp51B1 0.002 0.0027 0.0003
Echinococcus multilocularis somatostatin receptor 0.0315 0.1835 0.1835
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0315 0.1835 0.2531
Mycobacterium tuberculosis Probable cytochrome P450 130 Cyp130 0.002 0.0027 0.0003
Trichomonas vaginalis dihydroorotate dehydrogenase, putative 0.0463 0.2743 0.9883
Echinococcus granulosus neuropeptides capa receptor 0.0315 0.1835 0.1835
Onchocerca volvulus 0.0315 0.1835 1
Leishmania major dihydrolipoamide dehydrogenase, putative 0.002 0.0025 0.002
Onchocerca volvulus 0.0315 0.1835 1
Loa Loa (eye worm) hypothetical protein 0.006 0.027 0.0762
Loa Loa (eye worm) hypothetical protein 0.0047 0.0192 0.0544
Brugia malayi dihydrolipoyl dehydrogenase, mitochondrial precursor, putative 0.002 0.0025 0.002
Echinococcus granulosus 7tm_1 domain containing protein 0.0315 0.1835 0.1835
Mycobacterium ulcerans two component sensor kinase MprB 0.0043 0.0166 0.0198
Loa Loa (eye worm) hypothetical protein 0.0029 0.0083 0.0235
Leishmania major cytochrome p450-like protein 0.002 0.0027 0.0023
Brugia malayi Zinc finger, C2H2 type family protein 0.0463 0.2743 0.3814
Trypanosoma brucei heat shock protein, putative 0.021 0.1193 0.1633
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.0028 0.0072 0.0072
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0115 0.0607 0.0833
Echinococcus granulosus regulator of G protein signaling 7 0.0023 0.0046 0.0046
Brugia malayi nuclear hormone receptor 0.0028 0.0072 0.0086
Trichomonas vaginalis PIKK family atypical protein kinase 0.0115 0.0607 0.2117
Echinococcus multilocularis PIK kinase, FAT and Armadillo domain containing protein 0.005 0.021 0.021
Brugia malayi PXA domain containing protein 0.0023 0.0046 0.0049
Loa Loa (eye worm) TOPoisomerase family member 0.0043 0.0166 0.047
Mycobacterium ulcerans cytochrome P450 150A6 Cyp150A6 0.002 0.0027 0.0003
Echinococcus multilocularis rhodopsin orphan GPCR 0.0315 0.1835 0.1835
Treponema pallidum chemotaxis histidine kinase (cheA) 0.0043 0.0166 0.156
Trypanosoma cruzi phosphatidylinositol 3-kinase 2, putative 0.0022 0.0039 0.002
Mycobacterium tuberculosis Probable oxidoreductase 0.0145 0.0791 0.1071
Onchocerca volvulus DNA topoisomerase 2 homolog 0.0043 0.0166 0.0708
Leishmania major target of rapamycin (TOR) kinase 1, putative 0.0115 0.0607 0.0833
Trichomonas vaginalis phosphatidylinositol 3-kinase class, putative 0.0022 0.0039 0.0051
Trichomonas vaginalis high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0029 0.0082 0.0207
Echinococcus multilocularis fmrfamide receptor 0.0315 0.1835 0.1835
Chlamydia trachomatis two component regulatory system sensor histidine kinase 0.0056 0.0244 1
Loa Loa (eye worm) hypothetical protein 0.0315 0.1835 0.5188
Brugia malayi Calcitonin receptor-like protein seb-1 0.0149 0.0816 0.1125
Schistosoma mansoni regulator of G protein signaling 0.0023 0.0046 0.0029
Loa Loa (eye worm) glutathione reductase 0.0057 0.0254 0.0717
Leishmania major heat shock protein 83-1 0.021 0.1193 0.165
Loa Loa (eye worm) hypothetical protein 0.0023 0.0046 0.0129
Mycobacterium ulcerans sensor kinase from two component regulatory system 0.0043 0.0166 0.0198
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.0028 0.0072 0.0066
Loa Loa (eye worm) hypothetical protein 0.0315 0.1835 0.5188
Trichomonas vaginalis PIKK family atypical protein kinase 0.0115 0.0607 0.2117
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0033 0.0108 0.0301
Loa Loa (eye worm) hypothetical protein 0.0101 0.0521 0.1474
Leishmania major peptidyl-prolyl cis-trans isomerase/rotamase, putative,PPIase, putative 0.0039 0.0145 0.0188
Loa Loa (eye worm) hypothetical protein 0.0023 0.0046 0.0129
Loa Loa (eye worm) follicle stimulating hormone receptor 0.0593 0.3537 1
Trichomonas vaginalis PIKK family atypical protein kinase 0.0065 0.03 0.1002
Echinococcus granulosus neuropeptide s receptor 0.0315 0.1835 0.1835
Brugia malayi kinase, mitochondrial precursor 0.0043 0.0166 0.0217
Trichomonas vaginalis sensory transduction histidine kinase bacterial, putative 0.0043 0.0166 0.0514
Trypanosoma brucei phosphatidylinositol 4-kinase, putative 0.0022 0.0039 0.002
Trypanosoma cruzi hypothetical protein, conserved 0.0576 0.3435 0.4769
Loa Loa (eye worm) hypothetical protein 0.0028 0.0072 0.0205
Echinococcus multilocularis protein patched 0.0044 0.0171 0.0171
Brugia malayi AMP-binding enzyme family protein 0.0048 0.0196 0.0258
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0149 0.0816 0.1125
Echinococcus granulosus single minded 2 0.0039 0.0145 0.0145
Onchocerca volvulus 0.0315 0.1835 1
Trichomonas vaginalis PIKK family atypical protein kinase 0.0115 0.0607 0.2117
Echinococcus granulosus lysine specific demethylase 5A 0.0035 0.0121 0.0121
Trichomonas vaginalis two component sensor and regulator histidine kinase bacteria, putative 0.0043 0.0166 0.0514
Loa Loa (eye worm) hypothetical protein 0.0244 0.1401 0.3961
Echinococcus granulosus chromobox protein 1 0.0084 0.0419 0.0419
Trypanosoma cruzi developmentally regulated phosphoprotein, putative 0.0043 0.0166 0.0198
Trypanosoma brucei cytochrome P450, putative 0.003 0.0088 0.0088
Brugia malayi GnHR receptor homolog 0.0315 0.1835 0.2546
Brugia malayi Nuclear hormone receptor family member nhr-49 0.0028 0.0072 0.0086
Toxoplasma gondii Hsp90 domain-containing protein 0.0086 0.0432 0.0569
Leishmania major heat shock protein 83-1 0.021 0.1193 0.165
Trichomonas vaginalis PIKK family atypical protein kinase 0.0115 0.0607 0.2117
Schistosoma mansoni phosphatidylinositol-45-bisphosphate 3-kinase catalytic subunit alpha PI3K 0.0022 0.0039 0.002
Schistosoma mansoni jumonji domain containing protein 0.0076 0.0371 0.0484
Loa Loa (eye worm) steroid hormone receptor 0.0028 0.0072 0.0205
Schistosoma mansoni opsin-like receptor 0.0315 0.1835 0.2531
Leishmania major DNA topoisomerase ii 0.0043 0.0166 0.0217
Trichomonas vaginalis PIKK family atypical protein kinase 0.0022 0.0039 0.0051
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0036 0.0125 0.0139
Loa Loa (eye worm) hypothetical protein 0.0315 0.1835 0.5188
Loa Loa (eye worm) hypothetical protein 0.0028 0.0072 0.0205
Brugia malayi hypothetical protein 0.0315 0.1835 0.2546
Trichomonas vaginalis endoplasmin, putative 0.0129 0.0694 0.2434
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0251 0.1444 0.4081
Echinococcus multilocularis DNA topoisomerase 2 alpha 0.0043 0.0166 0.0166
Schistosoma mansoni ataxia telangiectasia mutated (atm) 0.0065 0.03 0.0385
Trichomonas vaginalis chromobox protein, putative 0.0084 0.0419 0.1433
Echinococcus multilocularis thyroid hormone receptor alpha 0.0028 0.0072 0.0072
Echinococcus granulosus heat shock protein 0.021 0.1193 0.1193
Treponema pallidum DNA gyrase, subunit B (gyrB) 0.0043 0.0166 0.156
Mycobacterium tuberculosis Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras 0.0145 0.0791 0.1071
Leishmania major phosphatidylinositol 4-kinase, putative 0.0022 0.0039 0.004
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0315 0.1835 0.1835
Trypanosoma brucei heat shock protein 90, putative 0.021 0.1193 0.1633
Loa Loa (eye worm) jmjC domain-containing protein 0.0035 0.0121 0.0342
Schistosoma mansoni cellular tumor antigen P53 0.006 0.027 0.0342
Echinococcus multilocularis phosphatidylinositol 4 phosphate 3 kinase C2 0.0022 0.0039 0.0039
Echinococcus granulosus heat shock protein 90 0.0168 0.093 0.093
Brugia malayi steroid hormone receptor 0.0028 0.0072 0.0086
Schistosoma mansoni growth hormone secretagogue receptor 0.0315 0.1835 0.2531
Echinococcus multilocularis regulator of G protein signaling 7 0.0023 0.0046 0.0046
Brugia malayi FAT domain containing protein 0.005 0.021 0.0279
Toxoplasma gondii non-specific serine/threonine protein kinase 0.0072 0.0346 0.0449
Echinococcus granulosus phosphatidylinositol 4 phosphate 3 kinase C2 0.0022 0.0039 0.0039
Echinococcus granulosus DNA topoisomerase 2 alpha 0.0043 0.0166 0.0166
Leishmania major phosphatidylinositol 3-kinase, putative 0.0115 0.0607 0.0833
Mycobacterium tuberculosis Probable dihydroorotate dehydrogenase PyrD 0.1187 0.7176 1
Entamoeba histolytica phosphatidylinositol3-kinaseTor2, putative 0.0115 0.0607 0.2076
Schistosoma mansoni neuropeptide F-like receptor 0.0315 0.1835 0.2531
Loa Loa (eye worm) heat shock protein 75 0.0086 0.0432 0.1221
Onchocerca volvulus 0.0315 0.1835 1
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0022 0.0039 0.004
Echinococcus granulosus g-protein coupled receptor 0.0315 0.1835 0.1835
Loa Loa (eye worm) hypothetical protein 0.0315 0.1835 0.5188
Schistosoma mansoni peptide (allatostatin)-like receptor 0.0315 0.1835 0.2531
Echinococcus multilocularis serine:threonine protein kinase SMG1 0.0065 0.03 0.03
Loa Loa (eye worm) hypothetical protein 0.0315 0.1835 0.5188
Onchocerca volvulus 0.005 0.0209 0.0947
Loa Loa (eye worm) hypothetical protein 0.0315 0.1835 0.5188
Trichomonas vaginalis calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative 0.0029 0.0082 0.0207
Trichomonas vaginalis cAMP/cGMP cyclic nucleotide phosphodiesterase, putative 0.0029 0.0082 0.0207
Brugia malayi Thioredoxin reductase 0.0057 0.0254 0.0339
Trichomonas vaginalis rod cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0029 0.0082 0.0207
Chlamydia trachomatis DNA gyrase subunit B 0.0043 0.0166 0.6447
Schistosoma mansoni amine GPCR 0.0315 0.1835 0.2531
Onchocerca volvulus 0.0315 0.1835 1
Trypanosoma cruzi Phosphatidylinositol 3-kinase tor2 0.0115 0.0607 0.0814
Brugia malayi chromobox protein homolog 3 0.0047 0.0193 0.0254
Loa Loa (eye worm) hypothetical protein 0.0315 0.1835 0.5188
Echinococcus multilocularis regulator of G protein signaling 3 0.0023 0.0046 0.0046
Onchocerca volvulus Neuropeptide F receptor homolog 0.0315 0.1835 1
Echinococcus granulosus sterol regulatory element binding protein 0.0044 0.0171 0.0171
Onchocerca volvulus 0.0315 0.1835 1
Loa Loa (eye worm) hypothetical protein 0.0315 0.1835 0.5188
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0035 0.0116 0.0116
Loa Loa (eye worm) hypothetical protein 0.0065 0.03 0.0849
Mycobacterium tuberculosis Possible two component sensor kinase TcrY 0.0043 0.0166 0.0198
Entamoeba histolytica peptidyl-prolyl cis-trans isomerase, putative 0.0039 0.0145 0.0387
Trichomonas vaginalis cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0029 0.0082 0.0207
Schistosoma mansoni hypothetical protein 0.0042 0.0162 0.0191
Mycobacterium leprae PROBABLE NADH DEHYDROGENASE NDH 0.013 0.0702 0.0944
Brugia malayi Dihydroorotate dehydrogenase, mitochondrial precursor, putative 0.1187 0.7176 1
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0065 0.03 0.0404
Brugia malayi ORL1-like opioid receptor 0.0315 0.1835 0.2546
Mycobacterium tuberculosis NAD(P)H quinone reductase LpdA 0.0145 0.0791 0.1071
Echinococcus granulosus G protein coupled receptor 139 0.0315 0.1835 0.1835
Plasmodium vivax multidomain scavenger receptor, putative 0.0024 0.005 0.0034
Trichomonas vaginalis sensor histidine kinase, putative 0.0043 0.0166 0.0514
Mycobacterium ulcerans hypothetical protein 0.0048 0.0196 0.0239
Trypanosoma brucei Phosphatidylinositol 3-kinase tor1 0.0115 0.0607 0.0814
Schistosoma mansoni biogenic amine (5HT) receptor 0.0315 0.1835 0.2531
Echinococcus granulosus regulator of G protein signaling 3 0.0023 0.0046 0.0046
Trichomonas vaginalis cGMP-dependent 3,5-cyclic phosphodiesterase, putative 0.0029 0.0082 0.0207
Echinococcus multilocularis GPCR, family 2 0.0047 0.0192 0.0192
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0036 0.0125 0.0125
Toxoplasma gondii heat shock protein 75, putative 0.0086 0.0432 0.0569
Schistosoma mansoni regulator of G protein signaling 0.0023 0.0046 0.0029
Echinococcus granulosus neuropeptide receptor 0.0315 0.1835 0.1835
Loa Loa (eye worm) hypothetical protein 0.0315 0.1835 0.5188
Brugia malayi follicle stimulating hormone receptor 0.0593 0.3537 0.4922
Trypanosoma cruzi cytochrome P450, putative 0.003 0.0088 0.0088
Schistosoma mansoni ataxia telangiectasia mutated (atm)-related 0.0115 0.0607 0.0814
Schistosoma mansoni hypothetical protein 0.002 0.0027 0.0003
Trichomonas vaginalis receptor histidine kinase, putative 0.0043 0.0166 0.0514
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0028 0.0072 0.0086
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.0028 0.0072 0.0072
Echinococcus granulosus peptide allatostatin:somatostatin 0.0315 0.1835 0.1835
Trichomonas vaginalis PIKK family atypical protein kinase 0.0115 0.0607 0.2117
Wolbachia endosymbiont of Brugia malayi signal transduction histidine kinase and receiver 0.0043 0.0166 0.0198
Entamoeba histolytica Phosphatidylinositol 3- and 4-kinase family 0.0065 0.03 0.0955
Echinococcus multilocularis rhodopsin orphan GPCR 0.0315 0.1835 0.1835
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0022 0.0039 0.004
Trichomonas vaginalis conserved hypothetical protein 0.0023 0.0046 0.0075
Brugia malayi Cytochrome P450 family protein 0.003 0.0088 0.0108
Loa Loa (eye worm) hypothetical protein 0.0036 0.0122 0.0344
Echinococcus multilocularis alpha 1A adrenergic receptor 0.0315 0.1835 0.1835
Loa Loa (eye worm) hypothetical protein 0.0043 0.0166 0.047
Plasmodium falciparum heat shock protein 90 0.021 0.1193 0.1633
Trypanosoma brucei heat shock protein, putative 0.021 0.1193 0.1633
Mycobacterium ulcerans cytochrome P450 188A3 Cyp188A3 0.002 0.0027 0.0003
Mycobacterium ulcerans long-chain-fatty-acid--CoA ligase 0.0048 0.0196 0.0239
Trichomonas vaginalis conserved hypothetical protein 0.0033 0.0108 0.0303
Mycobacterium tuberculosis Probable NADH dehydrogenase Ndh 0.013 0.0702 0.0947
Echinococcus multilocularis rhodopsin orphan GPCR 0.0315 0.1835 0.1835
Schistosoma mansoni hypothetical protein 0.0047 0.0192 0.0234
Trypanosoma brucei cAMP-specific phosphodiesterase 0.0029 0.0082 0.008
Schistosoma mansoni muscarinic acetylcholine (GAR) receptor 0.0315 0.1835 0.2531
Mycobacterium tuberculosis Probable cytochrome P450 144 Cyp144 0.002 0.0027 0.0003
Trichomonas vaginalis PIKK family atypical protein kinase 0.0065 0.03 0.1002
Schistosoma mansoni hypothetical protein 0.0042 0.0162 0.0191
Toxoplasma gondii heat shock protein HSP90 0.021 0.1193 0.1633
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.0028 0.0072 0.0072
Trichomonas vaginalis PIKK family atypical protein kinase 0.0022 0.0039 0.0051
Trichomonas vaginalis conserved hypothetical protein 0.0023 0.0046 0.0075
Plasmodium falciparum heat shock protein 90, putative 0.0086 0.0432 0.0569
Brugia malayi G-protein coupled receptor 0.0315 0.1835 0.2546
Echinococcus multilocularis rhodopsin orphan GPCR 0.0315 0.1835 0.1835
Trichomonas vaginalis regulator of G protein signaling 5, rgs5, putative 0.0023 0.0046 0.0075
Loa Loa (eye worm) RGS-3 protein 0.0023 0.0046 0.0129
Trichomonas vaginalis rotamase, putative 0.004 0.0151 0.0458
Echinococcus multilocularis phosphatidylinositol 3 and 4 kinase 0.0115 0.0607 0.0607
Toxoplasma gondii hypothetical protein 0.0021 0.0032 0.001
Loa Loa (eye worm) hypothetical protein 0.0043 0.0166 0.047
Brugia malayi Steroid receptor seven-up type 2 0.0028 0.0072 0.0086
Trypanosoma cruzi phosphatidylinositol 3-kinase, putative 0.0065 0.03 0.0385
Schistosoma mansoni patched 1 0.0044 0.0171 0.0205
Brugia malayi intermediate filament protein 0.0033 0.0103 0.0129
Loa Loa (eye worm) hypothetical protein 0.0315 0.1835 0.5188
Mycobacterium tuberculosis Two component sensor histidine kinase DosT 0.0064 0.0295 0.0377
Trichomonas vaginalis chromobox protein, putative 0.0084 0.0419 0.1433
Echinococcus granulosus regulator of G protein signaling 7 0.0023 0.0046 0.0046
Brugia malayi putative neuropeptide receptor NPR1 0.0315 0.1835 0.2546
Schistosoma mansoni heat shock protein 0.021 0.1193 0.1633
Loa Loa (eye worm) hypothetical protein 0.025 0.1437 0.4063
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0028 0.0072 0.0086
Entamoeba histolytica acyl-coA synthetase, putative 0.0048 0.0196 0.0572
Echinococcus multilocularis lamin 0.0033 0.0103 0.0103
Plasmodium vivax hypothetical protein, conserved 0.0029 0.0083 0.0081
Trichomonas vaginalis PIKK family atypical protein kinase 0.0065 0.03 0.1002
Mycobacterium ulcerans cytochrome P450 187A5 Cyp187A5 0.002 0.0027 0.0003
Loa Loa (eye worm) hypothetical protein 0.0315 0.1835 0.5188
Loa Loa (eye worm) hypothetical protein 0.0036 0.0122 0.0344
Trichomonas vaginalis chromobox protein, putative 0.0051 0.0215 0.069
Echinococcus multilocularis muscleblind protein 0.0152 0.0838 0.0838
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0072 0.0347 0.0347
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0065 0.03 0.0404
Loa Loa (eye worm) hypothetical protein 0.0315 0.1835 0.5188
Leishmania major mitochondrial DNA topoisomerase II 0.0043 0.0166 0.0217
Trypanosoma brucei heat shock protein, putative 0.021 0.1193 0.1633
Leishmania major developmentally regulated phosphoprotein-like protein 0.0043 0.0166 0.0217
Plasmodium vivax hypothetical protein 0.0022 0.0039 0.002
Echinococcus granulosus retinoic acid receptor rxr beta a 0.0028 0.0072 0.0072
Trichomonas vaginalis PIKK family atypical protein kinase 0.0115 0.0607 0.2117
Toxoplasma gondii phosphatidylinositol 3- and 4-kinase 0.0022 0.0039 0.002
Schistosoma mansoni adenoreceptor 0.0315 0.1835 0.2531
Loa Loa (eye worm) hypothetical protein 0.0022 0.0039 0.011
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0028 0.0072 0.0086
Echinococcus granulosus beta-adrenergic receptor kinase 0.0023 0.0046 0.0046
Trichomonas vaginalis heat shock protein, putative 0.0168 0.093 0.3291
Echinococcus granulosus g protein coupled receptor 0.0315 0.1835 0.1835
Entamoeba histolytica acyl-CoA synthetase, putative 0.0048 0.0196 0.0572
Mycobacterium ulcerans acyl-CoA synthetase 0.0048 0.0196 0.0239
Trichomonas vaginalis PIKK family atypical protein kinase 0.0115 0.0607 0.2117
Mycobacterium ulcerans dihydroorotate dehydrogenase 2 0.1187 0.7176 1
Echinococcus granulosus regulator of G protein signaling 3 0.0023 0.0046 0.0046
Trichomonas vaginalis phosphatidylinositol 3-kinase class, putative 0.0022 0.0039 0.0051
Onchocerca volvulus 0.0315 0.1835 1
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.0028 0.0072 0.0205
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD7 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0048 0.0196 0.0236
Schistosoma mansoni regulator of G protein signaling 0.0023 0.0046 0.0029
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD2 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0048 0.0196 0.0236
Mycobacterium ulcerans cytochrome P450 124A1, Cyp124A1 0.002 0.0027 0.0003
Echinococcus multilocularis neuropeptide FF receptor 2 0.0315 0.1835 0.1835
Loa Loa (eye worm) phosphatidylinositol 3 0.0022 0.0039 0.011
Loa Loa (eye worm) hypothetical protein 0.0315 0.1835 0.5188
Onchocerca volvulus 0.0315 0.1835 1
Mycobacterium tuberculosis Probable cytochrome P450 136 Cyp136 0.002 0.0027 0.0003
Brugia malayi putative neuropeptide receptor 0.0315 0.1835 0.2546
Leishmania major 4-coumarate:coa ligase-like protein 0.0048 0.0196 0.0258
Schistosoma mansoni bromodomain-containing nuclear protein 1 brd1 0.0029 0.0083 0.0081
Loa Loa (eye worm) hypothetical protein 0.0028 0.0072 0.0205
Plasmodium vivax phosphatidylinositol 4-kinase, putative 0.0022 0.0039 0.002
Echinococcus granulosus biogenic amine 5HT receptor 0.0315 0.1835 0.1835
Mycobacterium leprae conserved hypothetical protein 0.0021 0.0032 0.0007
Entamoeba histolytica hypothetical protein 0.0023 0.0046 0.0024
Echinococcus multilocularis 0.0022 0.0039 0.0039
Schistosoma mansoni opsin-like receptor 0.0315 0.1835 0.2531
Echinococcus multilocularis Zinc finger, PHD finger 0.0022 0.0039 0.0039
Loa Loa (eye worm) hypothetical protein 0.0044 0.0171 0.0484
Echinococcus granulosus geminin 0.0165 0.0916 0.0916
Onchocerca volvulus Dopamine\/Ecdysteroid receptor homolog 0.0315 0.1835 1
Brugia malayi Hsp90 protein 0.0086 0.0432 0.0588
Leishmania major heat shock protein 83-1 0.021 0.1193 0.165
Leishmania major 4-coumarate:coa ligase-like protein 0.0048 0.0196 0.0258
Schistosoma mansoni regulator of G protein signaling 17 19 20 (rgs17 19 20) 0.0023 0.0046 0.0029
Trypanosoma cruzi heat shock protein 90, putative 0.0168 0.093 0.1266
Trypanosoma cruzi Heat shock protein 83, putative 0.021 0.1193 0.1633
Leishmania major heat shock protein 83-1 0.021 0.1193 0.165
Loa Loa (eye worm) hypothetical protein 0.0028 0.0072 0.0205
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0022 0.0039 0.004
Schistosoma mansoni hypothetical protein 0.0022 0.0039 0.002
Echinococcus multilocularis neuropeptides capa receptor 0.0315 0.1835 0.1835
Leishmania major trypanothione reductase 0.0057 0.0254 0.0339
Schistosoma mansoni chromobox protein 0.0084 0.0419 0.0551
Trichomonas vaginalis calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative 0.0029 0.0082 0.0207
Trypanosoma cruzi phosphatidylinositol kinase, putative 0.0022 0.0039 0.002
Mycobacterium ulcerans two component regulator - sensor kinase 0.0043 0.0166 0.0198
Schistosoma mansoni ancient conserved domain protein 2 (cyclin m2) 0.0315 0.1835 0.2531
Trichomonas vaginalis conserved hypothetical protein 0.0033 0.0108 0.0303
Echinococcus multilocularis 7TM GPCR, rhodopsin 0.0315 0.1835 0.1835
Brugia malayi Dopamine receptor protein 1 0.0315 0.1835 0.2546
Brugia malayi Unidentified vitellogenin-linked transcript protein 6, putative 0.0315 0.1835 0.2546
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0036 0.0125 0.0139
Echinococcus multilocularis sex peptide receptor 0.0315 0.1835 0.1835
Brugia malayi MH2 domain containing protein 0.0117 0.062 0.085
Schistosoma mansoni alpha-1 adrenergic receptor 0.0315 0.1835 0.2531
Leishmania major heat shock protein 83-1 0.021 0.1193 0.165
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD2 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0048 0.0196 0.0239
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0315 0.1835 0.1835
Schistosoma mansoni rotamase 0.004 0.0151 0.0176
Loa Loa (eye worm) hypothetical protein 0.0315 0.1835 0.5188
Trichomonas vaginalis phopsphatidylinositol 3-kinase, drosophila, putative 0.0022 0.0039 0.0051
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.0028 0.0072 0.0066
Mycobacterium tuberculosis Possible cytochrome P450 126 Cyp126 0.002 0.0027 0.0003
Echinococcus granulosus axis inhibition protein axin 0.0023 0.0046 0.0046
Onchocerca volvulus 0.0315 0.1835 1
Loa Loa (eye worm) hypothetical protein 0.0315 0.1835 0.5188
Loa Loa (eye worm) hypothetical protein 0.0315 0.1835 0.5188
Onchocerca volvulus Phospholipase A2 homolog 0.0101 0.0521 0.2686
Echinococcus granulosus dihydrolipoamide dehydrogenase 0.002 0.0025 0.0025
Echinococcus granulosus rhodopsin orphan GPCR 0.0315 0.1835 0.1835
Loa Loa (eye worm) hypothetical protein 0.0101 0.0521 0.1474
Loa Loa (eye worm) MH2 domain-containing protein 0.0117 0.062 0.1753
Loa Loa (eye worm) hypothetical protein 0.0315 0.1835 0.5188
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.005 0.0209 0.0277
Brugia malayi Tachykinin-like peptides receptor 99D 0.0315 0.1835 0.2546
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0315 0.1835 0.1835
Trypanosoma cruzi mitochondrial DNA topoisomerase II, putative 0.0043 0.0166 0.0198
Onchocerca volvulus 0.0033 0.0103 0.0358
Loa Loa (eye worm) PHD-finger family protein 0.0029 0.0083 0.0235
Schistosoma mansoni hypothetical protein 0.0315 0.1835 0.2531
Trypanosoma cruzi phosphatidylinositol 3-related kinase, putative 0.0115 0.0607 0.0814
Echinococcus granulosus rhodopsin orphan GPCR 0.0315 0.1835 0.1835
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0022 0.0039 0.004
Schistosoma mansoni hypothetical protein 0.0102 0.0528 0.0703
Echinococcus granulosus tm gpcr rhodopsin 0.0315 0.1835 0.1835
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0036 0.0125 0.0139
Onchocerca volvulus Alhambra homolog 0.0029 0.0083 0.0246
Trichomonas vaginalis PIKK family atypical protein kinase 0.0115 0.0607 0.2117
Mycobacterium leprae Probable dihydroorotate dehydrogenase PyrD 0.1187 0.7176 1
Brugia malayi jmjC domain containing protein 0.0035 0.0121 0.0154
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0315 0.1835 0.2531
Echinococcus granulosus g protein coupled receptor 0.0315 0.1835 0.1835
Giardia lamblia Pms1-like protein 0.0043 0.0166 0.121
Loa Loa (eye worm) hypothetical protein 0.0315 0.1835 0.5188
Schistosoma mansoni dihydroorotate dehydrogenase 0.1187 0.7176 1
Entamoeba histolytica DNA topoisomerase II, putative 0.0043 0.0166 0.0465
Brugia malayi hypothetical protein 0.0315 0.1835 0.2546
Loa Loa (eye worm) hypothetical protein 0.0315 0.1835 0.5188
Brugia malayi Pre-SET motif family protein 0.0036 0.0125 0.0159
Trypanosoma cruzi dihydroorotate dehydrogenase, putative 0.1187 0.7176 1
Brugia malayi Serotonin receptor 0.0315 0.1835 0.2546
Plasmodium vivax hypothetical protein, conserved 0.0043 0.0166 0.0198
Leishmania major heat shock protein 83-1 0.021 0.1193 0.165
Toxoplasma gondii ATPase/histidine kinase/DNA gyrase B/HSP90 domain-containing protein 0.0043 0.0166 0.0198
Onchocerca volvulus 0.0286 0.1656 0.9005
Echinococcus granulosus pyroglutamylated rfamide peptide receptor 0.0315 0.1835 0.1835
Mycobacterium tuberculosis Probable membrane NADH dehydrogenase NdhA 0.013 0.0702 0.0947
Loa Loa (eye worm) hypothetical protein 0.0315 0.1835 0.5188
Plasmodium falciparum dihydroorotate dehydrogenase 0.1187 0.7176 1
Echinococcus granulosus serine:threonine protein kinase SMG1 0.0065 0.03 0.03
Echinococcus multilocularis neuropeptides capa receptor 0.0315 0.1835 0.1835
Trypanosoma brucei DNA topoisomerase II alpha, putative 0.0043 0.0166 0.0198
Loa Loa (eye worm) hypothetical protein 0.0024 0.005 0.014
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.0028 0.0072 0.0066
Echinococcus multilocularis peptide (allatostatin:somatostatin) 0.0315 0.1835 0.1835
Leishmania major heat shock protein 83-1 0.021 0.1193 0.165
Plasmodium falciparum glutathione reductase 0.0057 0.0254 0.032
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0315 0.1835 0.2531
Loa Loa (eye worm) hypothetical protein 0.0048 0.0196 0.0553
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0315 0.1835 0.2531
Brugia malayi cytochrome P450 0.002 0.0027 0.0023
Mycobacterium ulcerans acyl-CoA synthetase 0.0048 0.0196 0.0239
Echinococcus granulosus cAMP and cAMP inhibited cGMP 3'5' cyclic 0.0258 0.1487 0.1487
Schistosoma mansoni hypothetical protein 0.0029 0.0083 0.0081
Schistosoma mansoni RAR-like nuclear receptor 0.0028 0.0072 0.0066
Schistosoma mansoni endoplasmin 0.021 0.1193 0.1633
Echinococcus granulosus lamin dm0 0.0033 0.0103 0.0103
Loa Loa (eye worm) hypothetical protein 0.0028 0.0072 0.0205
Brugia malayi hypothetical protein 0.0024 0.005 0.0054
Trichomonas vaginalis PIKK family atypical protein kinase 0.0115 0.0607 0.2117
Echinococcus granulosus rhodopsin orphan GPCR 0.0315 0.1835 0.1835
Trichomonas vaginalis conserved hypothetical protein 0.0047 0.0193 0.061
Mycobacterium ulcerans cytochrome P450 144A4 Cyp144A4 0.002 0.0027 0.0003
Brugia malayi Serotonin receptor 0.0315 0.1835 0.2546
Echinococcus multilocularis muscleblind protein 1 0.0152 0.0838 0.0838
Echinococcus granulosus Phosphatidylinositol 4 kinase type 2 beta 0.0022 0.0039 0.0039
Echinococcus multilocularis dihydropyrimidine dehydrogenase (NADP+) 0.0469 0.2775 0.2775
Schistosoma mansoni niemann-pick C1 (NPC1) 0.0103 0.0537 0.0716
Entamoeba histolytica Niemann-Pick C1 protein, putative 0.0102 0.0527 0.1784
Loa Loa (eye worm) hypothetical protein 0.0315 0.1835 0.5188
Trypanosoma cruzi phosphatidylinositol kinase related protein, putative 0.0065 0.03 0.0385
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0047 0.0192 0.0192
Echinococcus granulosus expressed protein 0.0451 0.2666 0.2666
Trichomonas vaginalis PIKK family atypical protein kinase 0.0115 0.0607 0.2117
Brugia malayi Probable G protein-coupled receptor kinase F19C6.1, putative 0.0023 0.0046 0.0049
Loa Loa (eye worm) AGC/GRK/GRK protein kinase 0.0023 0.0046 0.0129
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0315 0.1835 0.2531
Trichomonas vaginalis conserved hypothetical protein 0.005 0.021 0.0674
Mycobacterium tuberculosis Two component sensor histidine kinase DevS 0.0064 0.0295 0.0377
Brugia malayi latrophilin 2 splice variant baaae 0.0102 0.0528 0.0722
Loa Loa (eye worm) hypothetical protein 0.0023 0.0046 0.0129
Onchocerca volvulus 0.0028 0.0072 0.0186
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0315 0.1835 0.1835
Schistosoma mansoni serine/threonine protein kinase 0.0023 0.0046 0.0029
Trypanosoma brucei target of rapamycin kinase 3, putative 0.0115 0.0607 0.0814
Schistosoma mansoni loxhd1 0.0024 0.005 0.0034
Mycobacterium tuberculosis Probable cytochrome P450 monooxygenase 142 Cyp142 0.002 0.0027 0.0003
Trichomonas vaginalis PIKK family atypical protein kinase 0.0115 0.0607 0.2117
Echinococcus multilocularis 0.002 0.0027 0.0027
Mycobacterium tuberculosis Two component sensor histidine kinase PrrB 0.0043 0.0166 0.0198
Brugia malayi hypothetical protein 0.0244 0.1401 0.1941
Mycobacterium ulcerans DNA gyrase subunit B 0.0043 0.0166 0.0198
Plasmodium vivax glutathione reductase, putative 0.0057 0.0254 0.032
Schistosoma mansoni endoplasmin 0.021 0.1193 0.1633
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0315 0.1835 0.1835
Echinococcus multilocularis Phosphatidylinositol 4 kinase type 2 beta 0.0022 0.0039 0.0039
Brugia malayi heat shock protein 90 0.021 0.1193 0.165
Loa Loa (eye worm) intermediate filament protein 0.0033 0.0103 0.0292
Mycobacterium tuberculosis Fatty-acid-AMP ligase FadD30 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) 0.0036 0.0122 0.0135
Loa Loa (eye worm) neuropeptide F receptor 0.0315 0.1835 0.5188
Onchocerca volvulus Phospholipase A2 homolog 0.0101 0.0521 0.2686
Loa Loa (eye worm) hypothetical protein 0.0315 0.1835 0.5188
Brugia malayi Nuclear hormone receptor family member nhr-40 0.0028 0.0072 0.0086
Mycobacterium tuberculosis Probable reductase 0.013 0.0702 0.0947
Trypanosoma brucei phosphatidylinositol 3-kinase, putative 0.0022 0.0039 0.002
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0028 0.0072 0.0066
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.0028 0.0072 0.0072
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD35 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0034 0.011 0.0119
Mycobacterium ulcerans two component sensory transduction histidine kinase MtrB 0.0043 0.0166 0.0198
Loa Loa (eye worm) hypothetical protein 0.0031 0.0093 0.0264
Echinococcus multilocularis neuropeptide Y receptor 0.0315 0.1835 0.1835
Loa Loa (eye worm) hypothetical protein 0.0229 0.1309 0.37
Echinococcus granulosus heat shock protein heat shock protein 90 alpha 0.0168 0.093 0.093
Trichomonas vaginalis PIKK family atypical protein kinase 0.0115 0.0607 0.2117
Trypanosoma cruzi phosphatidylinositol 3-kinase vps34-like 0.0022 0.0039 0.002
Schistosoma mansoni steroid hormone receptor ad4bp 0.0028 0.0072 0.0066
Echinococcus granulosus lamin 0.0033 0.0103 0.0103
Loa Loa (eye worm) hypothetical protein 0.0315 0.1835 0.5188
Mycobacterium leprae conserved hypothetical protein 0.0022 0.0039 0.0017
Brugia malayi larval opioid receptor 0.0315 0.1835 0.2546
Giardia lamblia Phosphoinositide-3-kinase, catalytic, alpha polypeptide 0.0022 0.0039 0.0121
Loa Loa (eye worm) hypothetical protein 0.0036 0.0125 0.0352
Onchocerca volvulus 0.006 0.027 0.1284
Trichomonas vaginalis rod cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0029 0.0082 0.0207
Schistosoma mansoni polycystin 1-related 0.0024 0.005 0.0034
Onchocerca volvulus Heat shock protein 75 kDa, mitochondrial homolog 0.0086 0.0432 0.2187
Loa Loa (eye worm) PXA domain-containing protein 0.0023 0.0046 0.0129
Brugia malayi hypothetical protein 0.0023 0.0046 0.0049
Loa Loa (eye worm) hypothetical protein 0.0029 0.0082 0.0232
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.0028 0.0072 0.0072
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0028 0.0072 0.0086
Trichomonas vaginalis conserved hypothetical protein 0.0023 0.0046 0.0075
Schistosoma mansoni neuropeptide receptor 0.0315 0.1835 0.2531
Echinococcus granulosus fmrfamide receptor 0.0315 0.1835 0.1835
Leishmania major target of rapamycin kinase (TOR) kinase 3 0.0115 0.0607 0.0833
Echinococcus granulosus lipoxygenase domain containing protein 0.0024 0.005 0.005
Schistosoma mansoni thyroid hormone receptor 0.0028 0.0072 0.0066
Trypanosoma cruzi cAMP specific phosphodiesterase, putative 0.0029 0.0082 0.008
Schistosoma mansoni axis inhibition protein axin 0.0023 0.0046 0.0029
Toxoplasma gondii PHD-finger domain-containing protein 0.0029 0.0083 0.0081
Trichomonas vaginalis phosphatidylinositol kinase, putative 0.0022 0.0039 0.0051
Echinococcus granulosus somatostatin receptor 0.0315 0.1835 0.1835
Trichomonas vaginalis PIKK family atypical protein kinase 0.0072 0.0346 0.1166
Wolbachia endosymbiont of Brugia malayi dihydroorotate dehydrogenase 2 0.1187 0.7176 1
Schistosoma mansoni hypothetical protein 0.0047 0.0192 0.0234
Trichomonas vaginalis PIKK family atypical protein kinase 0.0115 0.0607 0.2117
Leishmania major heat shock protein 83-1 0.021 0.1193 0.165
Trypanosoma brucei phosphatidylinositol 4-kinase, putative 0.0115 0.0607 0.0814
Loa Loa (eye worm) AGC/GRK/BARK protein kinase 0.0023 0.0046 0.0129
Loa Loa (eye worm) hypothetical protein 0.0315 0.1835 0.5188
Leishmania major heat shock protein 83-1 0.021 0.1193 0.165
Schistosoma mansoni retinoic acid receptor RXR 0.0028 0.0072 0.0066
Loa Loa (eye worm) neuropeptide F receptor 0.0315 0.1835 0.5188
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0036 0.0122 0.0135
Brugia malayi hypothetical protein 0.0315 0.1835 0.2546
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0315 0.1835 0.2531
Echinococcus multilocularis Phosphatidylinositol 4 kinase type 2 beta 0.0022 0.0039 0.0039
Toxoplasma gondii PHD-finger domain-containing protein 0.0029 0.0083 0.0081
Leishmania major 2-oxoglutarate dehydrogenase, e3 component, lipoamidedehydrogenase-like protein 0.002 0.0025 0.002
Trichomonas vaginalis cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0029 0.0082 0.0207
Onchocerca volvulus 0.0315 0.1835 1
Echinococcus multilocularis musashi 0.0033 0.0103 0.0103
Brugia malayi Doublecortin family protein 0.0024 0.005 0.0054
Schistosoma mansoni rab6-interacting 0.0024 0.005 0.0034
Schistosoma mansoni lamin 0.0033 0.0103 0.0109
Brugia malayi Dopamine receptor protein 1, putative (partial) 0.0315 0.1835 0.2546
Trypanosoma brucei DNA topoisomerase ii 0.0043 0.0166 0.0198
Loa Loa (eye worm) cytochrome P450 family protein 0.0064 0.0293 0.0829
Loa Loa (eye worm) doublecortin family protein 0.0024 0.005 0.014
Loa Loa (eye worm) hypothetical protein 0.005 0.021 0.0595
Onchocerca volvulus 0.0315 0.1835 1
Loa Loa (eye worm) hypothetical protein 0.0072 0.0346 0.0977
Mycobacterium tuberculosis Probable chaperone protein HtpG (heat shock protein) (HSP90 family protein) (high temperature protein G) 0.0168 0.093 0.1266
Brugia malayi hypothetical protein 0.0315 0.1835 0.2546
Toxoplasma gondii phosphatidylinositol 3- and 4-kinase 0.0022 0.0039 0.002
Mycobacterium tuberculosis Probable cytochrome P450 143 Cyp143 0.002 0.0027 0.0003
Brugia malayi Latrophilin receptor protein 2 0.0047 0.0192 0.0254
Brugia malayi G-protein coupled receptor 0.0315 0.1835 0.2546
Brugia malayi AMP-binding enzyme family protein 0.0048 0.0196 0.0258
Trypanosoma cruzi dihydroorotate dehydrogenase (fumarate), putative 0.1187 0.7176 1
Loa Loa (eye worm) hypothetical protein 0.0315 0.1835 0.5188
Echinococcus granulosus muscleblind protein 0.0152 0.0838 0.0838
Loa Loa (eye worm) hypothetical protein 0.0033 0.0103 0.0292
Entamoeba histolytica hypothetical protein 0.0065 0.03 0.0955
Echinococcus multilocularis survival motor neuron protein 1 0.0244 0.1401 0.1401
Echinococcus granulosus A kinase anchor protein 10 mitochondrial 0.0023 0.0046 0.0046
Toxoplasma gondii ATPase/histidine kinase/DNA gyrase B/HSP90 domain-containing protein 0.0043 0.0166 0.0198
Echinococcus multilocularis tachykinin peptides receptor 99D 0.0315 0.1835 0.1835
Brugia malayi Voltage-gated potassium channel, HERG (KCNH2)-related. C. elegans unc-103 ortholog 0.0036 0.0122 0.0156
Echinococcus multilocularis axis inhibition protein axin 0.0023 0.0046 0.0046
Echinococcus granulosus thioredoxin glutathione reductase 0.0057 0.0254 0.0254
Brugia malayi jmjC domain containing protein 0.0096 0.0492 0.0671
Mycobacterium ulcerans cytochrome P450 142A3 Cyp142A3 0.002 0.0027 0.0003
Mycobacterium ulcerans putative regulatory protein 0.0021 0.0032 0.001
Trypanosoma brucei heat shock protein 90, putative 0.021 0.1193 0.1633
Brugia malayi regulator of G-protein signaling egl-10 0.0023 0.0046 0.0049
Echinococcus multilocularis transfer RNA-Lys 0.0036 0.0125 0.0125
Toxoplasma gondii peptidylprolyl isomerase 0.0039 0.0145 0.0168
Mycobacterium ulcerans putative regulatory protein 0.0036 0.0125 0.014
Trypanosoma cruzi Phosphatidylinositol 3-kinase tor1 0.0115 0.0607 0.0814
Trichomonas vaginalis dihydroorotate dehydrogenase, putative 0.0469 0.2775 1
Loa Loa (eye worm) unidentified vitellogenin-linked transcript protein 6 0.0315 0.1835 0.5188
Trypanosoma cruzi cytochrome P450, putative 0.003 0.0088 0.0088
Schistosoma mansoni fkbp-rapamycin associated protein 0.0065 0.03 0.0385
Giardia lamblia Heat shock protein HSP 90-alpha 0.021 0.1193 1
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0047 0.0192 0.0192
Echinococcus granulosus neuropeptide Y receptor 0.0315 0.1835 0.1835
Mycobacterium tuberculosis Conserved hypothetical protein 0.0022 0.0039 0.002
Mycobacterium tuberculosis Probable two component sensor kinase 0.0043 0.0166 0.0198
Loa Loa (eye worm) hypothetical protein 0.0315 0.1835 0.5188
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0072 0.0347 0.0347
Trichomonas vaginalis high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0029 0.0082 0.0207
Schistosoma mansoni hypothetical protein 0.005 0.0209 0.0258
Echinococcus multilocularis thyrotropin releasing hormone receptor 0.0315 0.1835 0.1835
Trichomonas vaginalis conserved hypothetical protein 0.0021 0.0032 0.0027
Trypanosoma cruzi heat shock protein 90, putative 0.0124 0.0664 0.0894
Schistosoma mansoni hypothetical protein 0.0042 0.0162 0.0191
Mycobacterium tuberculosis Probable cytochrome P450 125 Cyp125 0.002 0.0027 0.0003
Brugia malayi Pin1-type peptidyl-prolyl cis-trans isomerase, BmPin1 0.004 0.0151 0.0196
Echinococcus multilocularis serotonin receptor 0.0315 0.1835 0.1835
Schistosoma mansoni regulator of G protein signaling 3 rgs3 0.0023 0.0046 0.0029
Trichomonas vaginalis DNA topoisomerase II, putative 0.0043 0.0166 0.0514
Echinococcus multilocularis rhodopsin orphan GPCR 0.0315 0.1835 0.1835
Mycobacterium ulcerans cytochrome P450 187A4 Cyp187A4 0.002 0.0027 0.0003
Leishmania major lanosterol 14-alpha-demethylase, putative 0.002 0.0027 0.0023
Trypanosoma brucei peptidyl-prolyl cis-trans isomerase/rotamase, putative 0.0039 0.0145 0.0168
Trypanosoma brucei trypanothione reductase 0.0057 0.0254 0.032
Echinococcus granulosus intermediate filament protein 0.0033 0.0103 0.0103
Trypanosoma brucei phosphatidylinositol 4-kinase alpha, putative 0.0022 0.0039 0.002
Mycobacterium ulcerans cytochrome P450 191A3 Cyp191A3 0.002 0.0027 0.0003
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.0028 0.0072 0.0072
Schistosoma mansoni phosphatidylinositol 3-and 4-kinase 0.0115 0.0607 0.0814
Echinococcus granulosus neuropeptide receptor 0.0315 0.1835 0.1835
Echinococcus granulosus RUN 0.0024 0.005 0.005
Brugia malayi ecdysteroid receptor 0.0028 0.0072 0.0086
Toxoplasma gondii phosphatidylinositol 3- and 4-kinase 0.0022 0.0039 0.002
Brugia malayi regulator of G-protein signaling rgs-7 0.0023 0.0046 0.0049
Mycobacterium ulcerans acyl-CoA synthetase 0.0048 0.0196 0.0239
Onchocerca volvulus 0.0315 0.1835 1
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0315 0.1835 0.1835
Leishmania major cytochrome p450-like protein 0.003 0.0088 0.0109
Plasmodium falciparum phd finger protein, putative 0.0029 0.0083 0.0081
Brugia malayi DNA gyrase/topoisomerase IV, A subunit family protein 0.0043 0.0166 0.0217
Echinococcus granulosus expressed conserved protein 0.0096 0.0489 0.0489
Mycobacterium tuberculosis Probable cytochrome P450 124 Cyp124 0.002 0.0027 0.0003
Mycobacterium leprae DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE 0.0145 0.0791 0.1068
Trichomonas vaginalis calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative 0.0029 0.0082 0.0207
Echinococcus granulosus neuropeptide Y receptor 0.0315 0.1835 0.1835
Loa Loa (eye worm) heterochromatin protein 1 0.0084 0.0419 0.1185
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.0028 0.0072 0.0066
Onchocerca volvulus 0.0315 0.1835 1
Echinococcus granulosus lipoxygenase domain containing protein 0.0024 0.005 0.005
Echinococcus multilocularis thioredoxin glutathione reductase 0.0057 0.0254 0.0254
Trypanosoma brucei heat shock protein, putative 0.021 0.1193 0.1633
Echinococcus multilocularis neuropeptide receptor 0.0315 0.1835 0.1835
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0036 0.0125 0.0125
Trichomonas vaginalis heat shock protein, putative 0.0168 0.093 0.3291
Trichomonas vaginalis cyclic nucleotide phosphodiesterase, putative 0.0029 0.0082 0.0207
Schistosoma mansoni serine/threonine protein kinase 0.0023 0.0046 0.0029
Mycobacterium ulcerans two component sensor histidine kinase TrcS 0.0043 0.0166 0.0198
Echinococcus granulosus PIK kinase FAT and Armadillo domain containing protein 0.005 0.021 0.021
Loa Loa (eye worm) hypothetical protein 0.0315 0.1835 0.5188
Loa Loa (eye worm) hypoxia-induced factor 1 0.0151 0.0831 0.2348
Trichomonas vaginalis cAMP-specific phosphodiesterase, putative 0.0029 0.0082 0.0207
Brugia malayi Nuclear hormone receptor family member nhr-31 0.0028 0.0072 0.0086
Plasmodium vivax phosphatidylinositol 4-kinase, putative 0.0022 0.0039 0.002
Trypanosoma brucei FAT domain/Rapamycin binding domain/Phosphatidylinositol 3- and 4-kinase, putative 0.0072 0.0346 0.0449
Schistosoma mansoni heat shock protein 0.0086 0.0432 0.0569
Trichomonas vaginalis PIKK family atypical protein kinase 0.0065 0.03 0.1002
Brugia malayi gonadotropin-releasing hormone receptor 2 0.0315 0.1835 0.2546
Mycobacterium ulcerans putative regulatory protein 0.0021 0.0032 0.001
Schistosoma mansoni Tr4/Tr2 (homologue) 0.0028 0.0072 0.0066
Loa Loa (eye worm) cytochrome P450 family protein 0.003 0.0088 0.0249
Brugia malayi Nuclear hormone receptor family member nhr-3 0.0028 0.0072 0.0086
Echinococcus granulosus tm gpcr rhodopsin 0.0315 0.1835 0.1835
Brugia malayi G-protein-linked acetylcholine receptor protein 2, putative 0.0315 0.1835 0.2546
Echinococcus multilocularis G protein coupled receptor 139 0.0315 0.1835 0.1835
Trichomonas vaginalis conserved hypothetical protein 0.0044 0.0171 0.0532
Trypanosoma cruzi heat shock protein, putative 0.0086 0.0432 0.0569
Schistosoma mansoni phosphatidylinositol 4-kinase 0.0022 0.0039 0.002
Loa Loa (eye worm) transcription factor SMAD2 0.0117 0.062 0.1753
Trichomonas vaginalis cGMP-dependent 3,5-cyclic phosphodiesterase, putative 0.0029 0.0082 0.0207
Plasmodium vivax hypothetical protein, conserved 0.0022 0.0039 0.002
Trypanosoma cruzi phosphatidylinositol 3-related kinase, putative 0.0115 0.0607 0.0814
Plasmodium falciparum GAF domain-related protein, putative 0.0021 0.0032 0.001
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0033 0.0108 0.0301
Loa Loa (eye worm) gonadotropin-releasing hormone receptor 2 0.0315 0.1835 0.5188
Leishmania major heat shock protein, putative 0.0086 0.0432 0.0588
Echinococcus granulosus G protein coupled 5 hydroxytryptamine receptor 0.0315 0.1835 0.1835
Echinococcus granulosus Protein patched homolog 1 0.0044 0.0171 0.0171
Echinococcus multilocularis sterol regulatory element binding protein 0.0044 0.0171 0.0171
Brugia malayi hypothetical protein 0.0164 0.0908 0.1253
Trichomonas vaginalis PIKK family atypical protein kinase 0.0115 0.0607 0.2117
Loa Loa (eye worm) hypothetical protein 0.0043 0.0166 0.047
Brugia malayi RE15519p 0.0315 0.1835 0.2546
Brugia malayi hypothetical protein 0.0023 0.0046 0.0049
Loa Loa (eye worm) abnormal chemotaxis protein 14 0.0044 0.0171 0.0484
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.0028 0.0072 0.0205
Echinococcus multilocularis chromobox protein 1 0.0084 0.0419 0.0419
Trichomonas vaginalis calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative 0.0029 0.0082 0.0207
Mycobacterium tuberculosis Probable cytochrome P450 138 Cyp138 0.002 0.0027 0.0003
Echinococcus granulosus Phosphatidylinositol 4 kinase type 2 beta 0.0022 0.0039 0.0039
Echinococcus multilocularis RUN 0.0024 0.005 0.005
Mycobacterium tuberculosis Probable cytochrome P450 128 Cyp128 0.002 0.0027 0.0003
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.0028 0.0072 0.0205
Trypanosoma cruzi phosphatidylinositol 4-kinase, putative 0.0022 0.0039 0.002
Mycobacterium leprae PUTATIVE TWO COMPONENT SENSOR HISTIDINE KINASE SENX3 0.0043 0.0166 0.0195
Echinococcus multilocularis endoplasmin 0.0168 0.093 0.093
Schistosoma mansoni hypothetical protein 0.0072 0.0347 0.0451
Leishmania major dihydroorotate dehydrogenase 0.1187 0.7176 1
Loa Loa (eye worm) hypothetical protein 0.0315 0.1835 0.5188
Loa Loa (eye worm) hypothetical protein 0.0315 0.1835 0.5188
Echinococcus granulosus neuropeptide receptor A26 0.0315 0.1835 0.1835
Schistosoma mansoni coup transcription factor 0.0028 0.0072 0.0066
Toxoplasma gondii hypothetical protein 0.0021 0.0032 0.001
Brugia malayi nuclear receptor NHR-88 0.0028 0.0072 0.0086
Trypanosoma cruzi phosphatidylinositol kinase related protein, putative 0.0043 0.0165 0.0196
Loa Loa (eye worm) hypothetical protein 0.0023 0.0046 0.0129
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0022 0.0039 0.004
Echinococcus granulosus Pyruvate dehydrogenase lipoamide kinase 0.0043 0.0166 0.0166
Echinococcus granulosus tumor protein p63 0.0408 0.2404 0.2404
Trypanosoma brucei heat shock protein, putative 0.021 0.1193 0.1633
Plasmodium vivax endoplasmin, putative 0.021 0.1193 0.1633
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0315 0.1835 0.2531
Schistosoma mansoni regulator of G protein signaling 0.0023 0.0046 0.0029
Schistosoma mansoni amine GPCR 0.0315 0.1835 0.2531
Echinococcus granulosus survival motor neuron protein 1 0.0244 0.1401 0.1401
Leishmania major heat shock protein 83-1 0.021 0.1193 0.165
Mycobacterium tuberculosis Two component sensor kinase [second part] 0.0043 0.0166 0.0198
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0315 0.1835 0.2531
Schistosoma mansoni neuropeptide receptor 0.0315 0.1835 0.2531
Mycobacterium ulcerans cytochrome P450 136A2 Cyp136A2 0.002 0.0027 0.0003
Onchocerca volvulus 0.0315 0.1835 1
Mycobacterium ulcerans cytochrome P450 125A7 Cyp125A7 0.002 0.0027 0.0003
Loa Loa (eye worm) hypothetical protein 0.0023 0.0046 0.0129
Giardia lamblia Hypothetical protein 0.0022 0.0039 0.0121
Schistosoma mansoni axis inhibition protein axin 0.0023 0.0046 0.0029
Echinococcus granulosus dro:myosuppressin receptor 0.0315 0.1835 0.1835
Trichomonas vaginalis high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0029 0.0082 0.0207
Trichomonas vaginalis rod cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0029 0.0082 0.0207
Schistosoma mansoni voltage-gated potassium channel 0.0039 0.0142 0.0164
Trichomonas vaginalis cone cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0029 0.0082 0.0207
Leishmania major 4-coumarate:coa ligase-like protein 0.0048 0.0196 0.0258
Plasmodium falciparum phosphatidylinositol 3-kinase 0.0022 0.0039 0.002
Trypanosoma cruzi dihydroorotate dehydrogenase, putative 0.0463 0.2743 0.3801
Trypanosoma brucei Lanosterol 14-alpha demethylase 0.002 0.0027 0.0003
Schistosoma mansoni phosphatidylinositol-45-bisphosphate 3-kinase catalytic subunit alpha PI3K 0.0022 0.0039 0.002
Trypanosoma brucei cAMP-specific phosphodiesterase 0.0029 0.0082 0.008
Leishmania major heat shock protein 83-1 0.021 0.1193 0.165
Loa Loa (eye worm) hypothetical protein 0.0315 0.1835 0.5188
Echinococcus granulosus tachykinin peptides receptor 99D 0.0315 0.1835 0.1835
Echinococcus multilocularis potassium voltage gated channel subfamily H 0.0036 0.0122 0.0122
Trichomonas vaginalis phosphatidylinositol 3-kinase class, putative 0.0022 0.0039 0.0051
Trichomonas vaginalis PIKK family atypical protein kinase 0.0115 0.0607 0.2117
Echinococcus granulosus 7TM GPCR rhodopsin 0.0315 0.1835 0.1835
Schistosoma mansoni amine GPCR 0.0315 0.1835 0.2531
Schistosoma mansoni lamin 0.0033 0.0103 0.0109
Giardia lamblia Grp94/Hsp90 0.0168 0.093 0.7752
Echinococcus multilocularis growth hormone secretagogue receptor type 1 0.0315 0.1835 0.1835
Trichomonas vaginalis PIKK family atypical protein kinase 0.0065 0.03 0.1002
Mycobacterium tuberculosis Probable sensor protein KdpD 0.0043 0.0166 0.0198
Brugia malayi AMP-binding enzyme family protein 0.0048 0.0196 0.0258
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0028 0.0072 0.0072
Leishmania major hypothetical protein, conserved 0.0043 0.0166 0.0217
Echinococcus multilocularis lipoxygenase domain containing protein 0.0024 0.005 0.005
Echinococcus granulosus Transcription factor JmjC domain containing protein 0.0096 0.0492 0.0492
Echinococcus multilocularis arachidonate 5 lipoxygenase 0.0067 0.0312 0.0312
Loa Loa (eye worm) hypothetical protein 0.0315 0.1835 0.5188
Trichomonas vaginalis PIKK family atypical protein kinase 0.0115 0.0607 0.2117
Loa Loa (eye worm) hypothetical protein 0.0053 0.0231 0.0654
Trichomonas vaginalis PIKK family atypical protein kinase 0.0115 0.0607 0.2117
Echinococcus multilocularis Regulator of G protein signaling 20 0.0023 0.0046 0.0046
Plasmodium falciparum endoplasmin, putative 0.0129 0.0694 0.0936
Trichomonas vaginalis mismatch repair protein Mlh1C (mutL homolog) 0.0043 0.0166 0.0514
Loa Loa (eye worm) hypothetical protein 0.0315 0.1835 0.5188
Schistosoma mansoni cgmp-dependent 35-cyclic phosphodiesterase 0.0029 0.0082 0.008
Entamoeba histolytica hypothetical protein 0.0023 0.0046 0.0024
Mycobacterium ulcerans cytochrome P450 189A7 Cyp189A7 0.002 0.0027 0.0003
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.0028 0.0072 0.0205
Echinococcus multilocularis pyroglutamylated rfamide peptide receptor 0.0315 0.1835 0.1835
Loa Loa (eye worm) hypothetical protein 0.0315 0.1835 0.5188
Plasmodium falciparum phosphatidylinositol 4-kinase 0.0022 0.0039 0.002
Trypanosoma cruzi phosphatidylinositol 4-kinase alpha, putative 0.0022 0.0039 0.002
Mycobacterium ulcerans cytochrome p450 150 cyp150 0.002 0.0027 0.0003
Trichomonas vaginalis rotamase, putative 0.0039 0.0145 0.0437
Trichomonas vaginalis PIKK family atypical protein kinase 0.0115 0.0607 0.2117
Entamoeba histolytica hypothetical protein 0.0072 0.0347 0.1127
Plasmodium vivax heat shock protein 90, putative 0.0086 0.0432 0.0569
Loa Loa (eye worm) phosphatidylinositol 4-kinase type 3 alpha isoform 1 0.0022 0.0039 0.011
Plasmodium falciparum DNA gyrase subunit B 0.0043 0.0166 0.0198
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0028 0.0072 0.0072
Mycobacterium ulcerans two component sensor histidine kinase SenX3 0.0043 0.0166 0.0198
Brugia malayi Probable 3',5'-cyclic phosphodiesterase C32E12.2, putative 0.0258 0.1487 0.206
Schistosoma mansoni lipoxygenase 0.0024 0.005 0.0034
Loa Loa (eye worm) hypothetical protein 0.0315 0.1835 0.5188
Echinococcus granulosus Polycystic kidney disease protein 0.0024 0.005 0.005
Mycobacterium tuberculosis Possible two component sensor kinase 0.0043 0.0166 0.0198
Trypanosoma cruzi phosphatidylinositol 3-kinase, putative 0.0022 0.0039 0.002
Echinococcus granulosus dihydropyrimidine dehydrogenase NADP 0.0469 0.2775 0.2775
Mycobacterium tuberculosis Possible two component system response sensor kinase membrane associated PhoR 0.0043 0.0166 0.0198
Mycobacterium tuberculosis Probable cytochrome P450 123 Cyp123 0.002 0.0027 0.0003
Loa Loa (eye worm) hypothetical protein 0.0037 0.013 0.0368
Echinococcus multilocularis beta adrenergic receptor kinase 0.0023 0.0046 0.0046
Loa Loa (eye worm) cytochrome P450 family protein 0.003 0.0088 0.0249
Trichomonas vaginalis PIKK family atypical protein kinase 0.0065 0.03 0.1002
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0149 0.0816 0.2308
Loa Loa (eye worm) hypothetical protein 0.0043 0.0165 0.0467
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.0033 0.0103 0.0292
Plasmodium falciparum DNA topoisomerase VI, b subunit, putative 0.0043 0.0166 0.0198
Mycobacterium leprae Probable two component sensor kinase MprB 0.0043 0.0166 0.0195
Schistosoma mansoni transcription factor LCR-F1 0.0072 0.0347 0.0451
Loa Loa (eye worm) hypothetical protein 0.0036 0.0122 0.0344
Trichomonas vaginalis phosphatidylinositol kinase, putative 0.0022 0.0039 0.0051
Brugia malayi bHLH-PAS transcription factor 0.0036 0.0125 0.016
Mycobacterium tuberculosis Putative ferredoxin reductase 0.013 0.0702 0.0947
Schistosoma mansoni jumonji/arid domain-containing protein 0.0035 0.0121 0.0134
Loa Loa (eye worm) hypothetical protein 0.0036 0.0122 0.0344
Mycobacterium ulcerans cytochrome P450 140A5 Cyp140A5 0.002 0.0027 0.0003
Loa Loa (eye worm) thioredoxin reductase 0.0057 0.0254 0.0717
Onchocerca volvulus 0.0036 0.0125 0.0481
Giardia lamblia Phosphoinositide-3-kinase, class 3 0.0022 0.0039 0.0121
Brugia malayi G protein-coupled receptor 0.0315 0.1835 0.2546
Mycobacterium ulcerans heat shock protein 90 0.0168 0.093 0.1266
Brugia malayi hypothetical protein 0.0315 0.1835 0.2546
Echinococcus granulosus GPCR family 2 0.0047 0.0192 0.0192
Leishmania major hypothetical protein, conserved 0.0598 0.357 0.4968
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD7 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0034 0.011 0.0119
Echinococcus granulosus heat shock protein 90 0.021 0.1193 0.1193
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0047 0.0192 0.0192
Schistosoma mansoni cytochrome P450 0.002 0.0027 0.0003
Echinococcus granulosus Niemann Pick C1 protein 0.0145 0.0795 0.0795
Entamoeba histolytica hypothetical protein 0.0072 0.0347 0.1127
Trichomonas vaginalis PIKK family atypical protein kinase 0.0115 0.0607 0.2117
Schistosoma mansoni phosphatidylinositol 4-kinase type-II 0.0022 0.0039 0.002
Mycobacterium leprae PROBABLE CHAPERONE PROTEIN HTPG (HEAT SHOCK PROTEIN) (HSP90 FAMILY PROTEIN) (HIGH TEMPERATURE PROTEIN G) 0.0168 0.093 0.1263
Trypanosoma cruzi target of rapamycin kinase 3 0.0115 0.0607 0.0814
Trichomonas vaginalis conserved hypothetical protein 0.0023 0.0046 0.0075
Schistosoma mansoni serine/threonine protein kinase 0.0023 0.0046 0.0029
Brugia malayi Niemann-Pick C1 protein precursor 0.0102 0.0527 0.0721
Trichomonas vaginalis calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative 0.0029 0.0082 0.0207
Schistosoma mansoni neuropeptide f receptor 76f 0.0315 0.1835 0.2531
Loa Loa (eye worm) hypothetical protein 0.0315 0.1835 0.5188
Mycobacterium tuberculosis Possible cytochrome P450 135B1 Cyp135B1 0.002 0.0027 0.0003
Echinococcus granulosus chromobox protein 1 0.0084 0.0419 0.0419
Mycobacterium tuberculosis Probable cytochrome P450 140 Cyp140 0.002 0.0027 0.0003
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0028 0.0072 0.0072
Trypanosoma cruzi peptidyl-prolyl cis-trans isomerase 0.0039 0.0145 0.0168
Trichomonas vaginalis conserved hypothetical protein 0.0023 0.0046 0.0075
Schistosoma mansoni regulator of G protein signaling 17 19 20 (rgs17 19 20) 0.0023 0.0046 0.0029
Loa Loa (eye worm) hypothetical protein 0.0028 0.0072 0.0205
Brugia malayi Serotonin/octopamine receptor family protein 7 0.0315 0.1835 0.2546
Schistosoma mansoni hypothetical protein 0.0047 0.0192 0.0234
Schistosoma mansoni histamine h1 receptor 0.0315 0.1835 0.2531
Toxoplasma gondii GAF domain-containing protein 0.0021 0.0032 0.001
Trypanosoma cruzi mitochondrial DNA topoisomerase II, putative 0.0043 0.0166 0.0198
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0315 0.1835 0.2531
Mycobacterium tuberculosis DNA gyrase (subunit B) GyrB (DNA topoisomerase (ATP-hydrolysing)) (DNA topoisomerase II) (type II DNA topoisomerase) 0.0043 0.0166 0.0198
Trichomonas vaginalis PIKK family atypical protein kinase 0.0115 0.0607 0.2117
Trichomonas vaginalis high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0029 0.0082 0.0207
Echinococcus granulosus phosphatidylinositol 3 and 4 kinase 0.0115 0.0607 0.0607
Plasmodium vivax DNA gyrase subunit B, putative 0.0043 0.0166 0.0198
Plasmodium vivax phosphatidylinositol 3- and 4-kinase, putative 0.0022 0.0039 0.002
Trichomonas vaginalis PIKK family atypical protein kinase 0.0043 0.0165 0.0509
Mycobacterium ulcerans cytochrome P450 123A3 Cyp123A3 0.002 0.0027 0.0003
Echinococcus multilocularis lamin dm0 0.0033 0.0103 0.0103
Wolbachia endosymbiont of Brugia malayi heat shock protein 90 0.0168 0.093 0.1266
Brugia malayi hypothetical protein 0.0315 0.1835 0.2546
Echinococcus granulosus FTZ F1 alpha 0.0028 0.0072 0.0072
Echinococcus granulosus phosphatidylinositol 45 bisphosphate 3 kinase 0.0022 0.0039 0.0039
Loa Loa (eye worm) hypothetical protein 0.0164 0.0908 0.2568
Echinococcus granulosus phosphatidylinositol 3 kinase catalytic subunit 0.0022 0.0039 0.0039
Trypanosoma cruzi cytochrome p450-like protein, putative 0.002 0.0027 0.0003
Echinococcus multilocularis regulator of G protein signaling 3 0.0023 0.0046 0.0046
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.0028 0.0072 0.0205
Brugia malayi Cytochrome P450 family protein 0.0064 0.0293 0.0394
Trichomonas vaginalis calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative 0.0029 0.0082 0.0207
Echinococcus multilocularis atpase aaa+ type core atpase aaa type core 0.0838 0.5038 0.5038
Brugia malayi Nuclear hormone receptor family member nhr-1 0.0028 0.0072 0.0086
Brugia malayi hypothetical protein 0.0024 0.005 0.0054
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.005 0.0209 0.0257
Brugia malayi Melatonin receptor type 1A 0.0315 0.1835 0.2546
Trypanosoma cruzi phosphatidylinositol 4-kinase, putative 0.0022 0.0039 0.002
Mycobacterium tuberculosis Probable chain -fatty-acid-CoA ligase FadD13 (fatty-acyl-CoA synthetase) 0.0048 0.0196 0.0239
Echinococcus multilocularis dual 3',5' cyclic AMP and GMP phosphodiesterase 0.0029 0.0082 0.0082
Trichomonas vaginalis cGMP-dependent 3,5-cyclic phosphodiesterase, putative 0.0029 0.0082 0.0207
Echinococcus multilocularis biogenic amine (5HT) receptor 0.0315 0.1835 0.1835
Toxoplasma gondii dihydroorotate dehydrogenase reveal, putative 0.1187 0.7176 1
Echinococcus granulosus arachidonate 5 lipoxygenase 0.0067 0.0312 0.0312
Echinococcus multilocularis dihydrolipoamide dehydrogenase 0.002 0.0025 0.0025
Trypanosoma brucei heat shock protein, putative 0.021 0.1193 0.1633
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.0028 0.0072 0.0186
Mycobacterium ulcerans long-chain-fatty-acid-CoA ligase 0.0048 0.0196 0.0239
Loa Loa (eye worm) hypothetical protein 0.0028 0.0072 0.0205
Echinococcus multilocularis g protein coupled receptor 0.0315 0.1835 0.1835
Trichomonas vaginalis cAMP-specific 3,5-cyclic phosphodiesterase, putative 0.0029 0.0082 0.0207
Brugia malayi hypothetical protein 0.0072 0.0347 0.047
Loa Loa (eye worm) heat shock protein 90 0.021 0.1193 0.3372
Trichomonas vaginalis PIKK family atypical protein kinase 0.0065 0.03 0.1002
Echinococcus multilocularis Polycystic kidney disease protein 0.0024 0.005 0.005
Plasmodium falciparum DNA topoisomerase 2 0.0043 0.0166 0.0198
Trypanosoma cruzi heat shock protein 90, putative 0.021 0.1193 0.1633
Trichomonas vaginalis conserved hypothetical protein 0.0043 0.0165 0.0509
Trypanosoma cruzi DNA topoisomerase II, putative 0.0043 0.0166 0.0198
Onchocerca volvulus 0.0024 0.005 0.0059
Schistosoma mansoni peptide (FMRFamide/neurokinin-3)-like receptor 0.0315 0.1835 0.2531
Mycobacterium leprae Probable two-component sensor kinase 0.0043 0.0166 0.0195
Brugia malayi Muscleblind-like protein 0.0152 0.0838 0.1154
Trypanosoma brucei Heat shock protein 83, putative 0.021 0.1193 0.1633
Toxoplasma gondii hypothetical protein 0.0021 0.0032 0.001
Leishmania major cytochrome p450-like protein 0.002 0.0027 0.0023
Echinococcus multilocularis tumor protein p63 0.0408 0.2404 0.2404
Trypanosoma brucei heat shock protein, putative 0.021 0.1193 0.1633
Leishmania major lipophosphoglycan biosynthetic protein, putative,heat shock protein 90, putative,glucose regulated protein 94, putative 0.0168 0.093 0.1284
Loa Loa (eye worm) melatonin receptor type 1A 0.0315 0.1835 0.5188
Echinococcus granulosus peregrin 0.0029 0.0083 0.0083
Toxoplasma gondii thioredoxin reductase 0.0057 0.0254 0.032
Trichomonas vaginalis cyclic nucleotide phosphodiesterase, putative 0.0029 0.0082 0.0207
Loa Loa (eye worm) hypothetical protein 0.0022 0.0039 0.011
Leishmania major heat shock protein 83-1 0.021 0.1193 0.165
Leishmania major phosphatidylinositol kinase, putative 0.0022 0.0039 0.004
Loa Loa (eye worm) phosphatidylinositol 3 0.0022 0.0039 0.011
Mycobacterium ulcerans cytochrome P450 143A4 Cyp143A4 0.002 0.0027 0.0003
Trypanosoma cruzi peptidyl-prolyl cis-trans isomerase 0.0039 0.0145 0.0168
Plasmodium falciparum heat shock protein 90, putative 0.0086 0.0432 0.0569
Onchocerca volvulus 0.005 0.0209 0.0946
Schistosoma mansoni chromobox protein 0.0084 0.0419 0.0551
Echinococcus granulosus orexin receptor type 2 0.0315 0.1835 0.1835
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0022 0.0039 0.004
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0315 0.1835 0.2531
Loa Loa (eye worm) hypothetical protein 0.0315 0.1835 0.5188
Trichomonas vaginalis PIKK family atypical protein kinase 0.0115 0.0607 0.2117
Schistosoma mansoni hypothetical protein 0.0042 0.0162 0.0191
Echinococcus multilocularis g protein coupled receptor 0.0315 0.1835 0.1835
Echinococcus multilocularis heat shock protein 90 0.0168 0.093 0.093
Trichomonas vaginalis phosphatidylinositol 4-kinase, putative 0.0022 0.0039 0.0051
Brugia malayi hypothetical protein 0.0315 0.1835 0.2546
Trichomonas vaginalis high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0029 0.0082 0.0207
Schistosoma mansoni hypothetical protein 0.0315 0.1835 0.2531
Entamoeba histolytica 90 kDa heat shock protein, putative 0.0086 0.0432 0.1435
Entamoeba histolytica heat shock protein 90, putative 0.021 0.1193 0.4215
Trichomonas vaginalis PIKK family atypical protein kinase 0.0115 0.0607 0.2117
Wolbachia endosymbiont of Brugia malayi DNA gyrase, topoisomerase II, B subunit, GyrB 0.0043 0.0166 0.0198
Echinococcus multilocularis ecdysone induced protein 78C 0.0028 0.0072 0.0072
Loa Loa (eye worm) hypothetical protein 0.0024 0.005 0.014
Plasmodium vivax heat shock protein 86, putative 0.021 0.1193 0.1633
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0315 0.1835 0.2531
Trichomonas vaginalis phosphatidylinositol 3-kinase catalytic subunit alpha, beta, delta, putative 0.0022 0.0039 0.0051
Echinococcus granulosus neuropeptide FF receptor 2 0.0315 0.1835 0.1835
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.0028 0.0072 0.0205
Mycobacterium tuberculosis Probable cytochrome P450 137 Cyp137 0.002 0.0027 0.0003
Schistosoma mansoni amine GPCR 0.0315 0.1835 0.2531
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.0028 0.0072 0.0072
Trichomonas vaginalis cGMP-inhibited 3,5-cyclic phosphodiesterase, putative 0.0029 0.0082 0.0207
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0047 0.0192 0.0192
Trichomonas vaginalis conserved hypothetical protein 0.0023 0.0046 0.0075
Echinococcus granulosus potassium voltage gated channel subfamily H 0.0036 0.0122 0.0122
Echinococcus multilocularis dihydropyrimidine dehydrogenase (NADP+) 0.0469 0.2775 0.2775
Loa Loa (eye worm) G-protein coupled receptor 0.0315 0.1835 0.5188
Loa Loa (eye worm) jmjC domain-containing protein 0.006 0.0274 0.0776
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0028 0.0072 0.0086
Loa Loa (eye worm) hypothetical protein 0.0315 0.1835 0.5188
Brugia malayi hypothetical protein 0.0315 0.1835 0.2546
Plasmodium falciparum acyl-CoA synthetase 0.0036 0.0122 0.0135
Echinococcus multilocularis g-protein coupled receptor 0.0315 0.1835 0.1835
Loa Loa (eye worm) hypothetical protein 0.0102 0.0527 0.149
Trichomonas vaginalis PIKK family atypical protein kinase 0.0022 0.0039 0.0051
Schistosoma mansoni histamine-responsive GPCR (AAF21638) 0.0315 0.1835 0.2531
Loa Loa (eye worm) hypothetical protein 0.0315 0.1835 0.5188
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.0028 0.0072 0.0072
Schistosoma mansoni intermediate filament proteins 0.0033 0.0103 0.0109
Entamoeba histolytica FKBP-rapamycin associated protein (FRAP), putative 0.0115 0.0607 0.2076
Schistosoma mansoni myosin xvIII 0.0315 0.1835 0.2531
Echinococcus multilocularis peregrin 0.0029 0.0083 0.0083
Mycobacterium tuberculosis Probable dehydrogenase 0.013 0.0702 0.0947
Schistosoma mansoni voltage-gated potassium channel 0.0039 0.0142 0.0164
Trypanosoma brucei phosphatidylinositol 3-kinase tor, putative 0.0022 0.0039 0.002
Echinococcus multilocularis lipoxygenase domain containing protein 0.0024 0.005 0.005
Trypanosoma cruzi dihydroorotate dehydrogenase, putative 0.1187 0.7176 1
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0115 0.0607 0.0833
Schistosoma mansoni phosphatidylinositol 4-kinase 0.0022 0.0039 0.002
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0047 0.0192 0.0254
Trichomonas vaginalis phosphatidylinositol 3-kinase catalytic subunit alpha, beta, delta, putative 0.0022 0.0039 0.0051
Echinococcus granulosus hypothetical protein 0.0315 0.1835 0.1835
Echinococcus granulosus biogenic amine 5HT receptor 0.0315 0.1835 0.1835
Loa Loa (eye worm) hypothetical protein 0.0315 0.1835 0.5188
Trichomonas vaginalis heat shock protein, putative 0.0129 0.0694 0.2434
Mycobacterium ulcerans two component sensor histidine kinase PrrB 0.0043 0.0166 0.0198
Plasmodium vivax heat shock protein, putative 0.0086 0.0432 0.0569
Echinococcus multilocularis expressed conserved protein 0.0096 0.0489 0.0489
Echinococcus multilocularis cAMP and cAMP inhibited cGMP 3',5' cyclic 0.0258 0.1487 0.1487
Schistosoma mansoni neuropeptide F-like receptor 0.0315 0.1835 0.2531
Schistosoma mansoni biogenic amine (octopamine/dopamine) receptor 0.0315 0.1835 0.2531
Trypanosoma cruzi Lanosterol 14-alpha demethylase 0.002 0.0027 0.0003
Loa Loa (eye worm) cytochrome P450 0.002 0.0027 0.0077
Loa Loa (eye worm) hypothetical protein 0.0315 0.1835 0.5188
Echinococcus multilocularis A kinase anchor protein 10, mitochondrial 0.0023 0.0046 0.0046
Trichomonas vaginalis cone cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0029 0.0082 0.0207
Onchocerca volvulus Bile acid receptor homolog 0.0028 0.0072 0.0186
Trypanosoma brucei phosphatidylinositol kinase related protein, putative 0.0065 0.03 0.0385
Brugia malayi Nuclear hormone receptor-like 1 0.0028 0.0072 0.0086
Echinococcus granulosus axis inhibition protein axin 0.0023 0.0046 0.0046
Giardia lamblia PHD finger protein 15 0.0029 0.0083 0.0499
Brugia malayi Dopamine receptor 0.0315 0.1835 0.2546
Loa Loa (eye worm) hypothetical protein 0.005 0.0211 0.0598
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0315 0.1835 0.2531
Mycobacterium tuberculosis Cytochrome P450 51 Cyp51 (CYPL1) (P450-L1A1) (sterol 14-alpha demethylase) (lanosterol 14-alpha demethylase) (P450-14DM) 0.002 0.0027 0.0003
Mycobacterium tuberculosis Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB 0.013 0.0702 0.0947
Echinococcus multilocularis regulator of G protein signaling 0.0023 0.0046 0.0046
Echinococcus granulosus FKBP12 rapamycin complex associated protein 0.0115 0.0607 0.0607
Loa Loa (eye worm) phosphatidylinositol 3 0.0022 0.0039 0.011
Plasmodium vivax SET domain protein, putative 0.0036 0.0125 0.0139
Trichomonas vaginalis phosphatidylinositol kinase, putative 0.0022 0.0039 0.0051
Trypanosoma brucei developmentally regulated phosphoprotein 0.0043 0.0166 0.0198
Schistosoma mansoni phosphatidylinositol-45-bisphosphate 3-kinase catalytic subunit alpha PI3K 0.0022 0.0039 0.002
Loa Loa (eye worm) cytoplasmic intermediate filament protein 0.0017 0.0011 0.003
Trichomonas vaginalis heat shock protein, putative 0.0168 0.093 0.3291
Brugia malayi PHD-finger family protein 0.0029 0.0083 0.0101
Schistosoma mansoni biogenic amine receptor 0.0315 0.1835 0.2531
Trypanosoma brucei phosphatidylinositol 3-kinase, putative 0.0115 0.0607 0.0814
Trichomonas vaginalis phopsphatidylinositol 3-kinase, drosophila, putative 0.0022 0.0039 0.0051
Trypanosoma cruzi phosphatidylinositol 3-kinase 2, putative 0.0022 0.0039 0.002
Brugia malayi photoreceptor-specific nuclear receptor 0.0028 0.0072 0.0086
Brugia malayi Regulator of G protein signaling domain containing protein 0.0023 0.0046 0.0049
Loa Loa (eye worm) hypothetical protein 0.0149 0.0816 0.2308
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.0028 0.0072 0.0205
Entamoeba histolytica hypothetical protein 0.0072 0.0347 0.1127
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0315 0.1835 0.2531
Echinococcus multilocularis Niemann Pick C1 protein 0.0145 0.0795 0.0795
Echinococcus multilocularis protein dispatched 1 0.005 0.0209 0.0209
Trypanosoma brucei dihydroorotate dehydrogenase (fumarate) 0.1187 0.7176 1
Trypanosoma cruzi heat shock protein 85, putative 0.021 0.1193 0.1633
Schistosoma mansoni thyroid hormone receptor 0.0028 0.0072 0.0066
Loa Loa (eye worm) hypothetical protein 0.0102 0.0528 0.1492
Echinococcus granulosus expressed protein 0.004 0.0151 0.0151
Toxoplasma gondii FATC domain-containing protein 0.0065 0.03 0.0385
Trypanosoma cruzi cAMP specific phosphodiesterase, putative 0.0029 0.0082 0.008
Brugia malayi Nuclear hormone receptor family member nhr-41 0.0028 0.0072 0.0086
Schistosoma mansoni neuropeptide receptor 0.0315 0.1835 0.2531
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0315 0.1835 0.2531
Echinococcus multilocularis neuropeptide receptor A26 0.0315 0.1835 0.1835
Onchocerca volvulus 0.0033 0.0103 0.0358
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0028 0.0072 0.0086
Schistosoma mansoni jumonji/arid domain-containing protein 0.0035 0.0121 0.0134
Mycobacterium ulcerans cytochrome P450 143A3 Cyp143A3 0.002 0.0027 0.0003
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0048 0.0196 0.0239
Loa Loa (eye worm) phosphatidylinositol kinase 0.0022 0.0039 0.011
Echinococcus granulosus jumonji domain containing protein 0.0041 0.0153 0.0153
Onchocerca volvulus 0.0024 0.005 0.0059
Onchocerca volvulus DNA topoisomerase 2 homolog 0.0043 0.0166 0.0708
Mycobacterium leprae TWO COMPONENT SENSOR HISTIDINE KINASE PRRB 0.0043 0.0166 0.0195
Onchocerca volvulus 0.0048 0.0196 0.0871
Trichomonas vaginalis PIKK family atypical protein kinase 0.0115 0.0607 0.2117
Schistosoma mansoni z-protein (S1r protein) 0.0023 0.0046 0.0029
Trichomonas vaginalis sensory transduction histidine kinase, putative 0.0043 0.0166 0.0514
Entamoeba histolytica dihydropyrimidine dehydrogenase, putative 0.0469 0.2775 1
Echinococcus multilocularis Transcription factor, JmjC domain containing protein 0.0096 0.0492 0.0492
Mycobacterium tuberculosis Probable cytochrome P450 139 Cyp139 0.002 0.0027 0.0003
Trypanosoma brucei Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase, putative 0.0043 0.0166 0.0198
Trichomonas vaginalis phosphatidylinositol kinase, putative 0.0022 0.0039 0.0051
Echinococcus multilocularis expressed protein 0.004 0.0151 0.0151
Onchocerca volvulus Putative DNA topoisomerase 2, mitochondrial 0.0043 0.0166 0.0708
Trypanosoma cruzi Lanosterol 14-alpha demethylase 0.002 0.0027 0.0003
Mycobacterium tuberculosis Possible cytochrome P450 135A1 Cyp135A1 0.002 0.0027 0.0003
Onchocerca volvulus 0.0315 0.1835 1
Loa Loa (eye worm) hypothetical protein 0.0315 0.1835 0.5188
Mycobacterium ulcerans putative regultory protein 0.0043 0.0166 0.0198
Echinococcus multilocularis g protein coupled receptor 0.0315 0.1835 0.1835
Schistosoma mansoni biogenic amine (5HT) receptor 0.0315 0.1835 0.2531
Trypanosoma cruzi heat shock protein 85, putative 0.021 0.1193 0.1633
Trichomonas vaginalis PIKK family atypical protein kinase 0.0115 0.0607 0.2117
Echinococcus granulosus histone lysine methyltransferase setb 0.0036 0.0125 0.0125
Toxoplasma gondii target of rapamycin (TOR), putative 0.0115 0.0607 0.0814
Trichomonas vaginalis dihydroorotate dehydrogenase, putative 0.0463 0.2743 0.9883
Leishmania major dihydrolipoamide dehydrogenase, putative 0.002 0.0025 0.002
Echinococcus multilocularis jumonji domain containing protein 0.0041 0.0153 0.0153
Echinococcus multilocularis dro:myosuppressin receptor 0.0315 0.1835 0.1835
Loa Loa (eye worm) hypothetical protein 0.0048 0.0196 0.0553
Chlamydia trachomatis acylglycerophosphoethanolamine acyltransferase 0.0036 0.0122 0.4419
Plasmodium vivax thioredoxin reductase, putative 0.0057 0.0254 0.032
Schistosoma mansoni hypothetical protein 0.0315 0.1835 0.2531
Echinococcus granulosus phosphatidylinositol 4 kinase beta 0.0022 0.0039 0.0039
Treponema pallidum heat shock protein 90 0.0168 0.093 1
Mycobacterium ulcerans cytochrome P450 108B4 Cyp108B4 0.002 0.0027 0.0003
Echinococcus multilocularis G protein coupled 5 hydroxytryptamine receptor 0.0315 0.1835 0.1835
Trichomonas vaginalis cyclic nucleotide phosphodiesterase, putative 0.0029 0.0082 0.0207
Loa Loa (eye worm) G-protein-linked acetylcholine receptor protein 2 0.0315 0.1835 0.5188
Loa Loa (eye worm) hypothetical protein 0.0152 0.0838 0.2369
Echinococcus multilocularis rhodopsin orphan GPCR 0.0315 0.1835 0.1835
Mycobacterium ulcerans two component system response phosphate sensor kinase, PhoR 0.0043 0.0166 0.0198
Schistosoma mansoni amine GPCR 0.0315 0.1835 0.2531
Loa Loa (eye worm) hypothetical protein 0.0315 0.1835 0.5188
Schistosoma mansoni phosphatidylinositol 3-kinase class 0.0022 0.0039 0.002

Activities

Activity type Activity value Assay description Source Reference
AC50 (functional) PUBCHEM_BIOASSAY: Cytochrome panel assay with activity outcomes. (Class of assay: other) Panel member name: p450-cyp2d6 Compounds with AC50 equal or less than 10 uM are considered active ChEMBL. No reference
AC50 (functional) PUBCHEM_BIOASSAY: Cytochrome panel assay with activity outcomes. (Class of assay: other) Panel member name: p450-cyp3a4 Compounds with AC50 equal or less than 10 uM are considered active ChEMBL. No reference
AC50 (functional) PUBCHEM_BIOASSAY: Cytochrome panel assay with activity outcomes. (Class of assay: other) Panel member name: p450-cyp1a2 Compounds with AC50 equal or less than 10 uM are considered active ChEMBL. No reference
AC50 (functional) PUBCHEM_BIOASSAY: Cytochrome panel assay with activity outcomes. (Class of assay: other) Panel member name: p450-cyp2c9 Compounds with AC50 equal or less than 10 uM are considered active ChEMBL. No reference
AC50 (functional) PUBCHEM_BIOASSAY: Cytochrome panel assay with activity outcomes. (Class of assay: other) Panel member name: p450-cyp2c19 Compounds with AC50 equal or less than 10 uM are considered active ChEMBL. No reference
Potency (functional) = 0.0251 um PUBCHEM_BIOASSAY: qHTS Screen for Compounds that Selectively Target Cancer Cells with p53 Mutations: Cytotoxicity of p53ts Cells at the Nonpermissive Temperature. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) = 0.0631 um PUBCHEM_BIOASSAY: qHTS Assay for Antagonists of Acetylcholine Muscarinic M1 Receptor: Kinetic Measurement of Intracellular Calcium Response. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) = 1.2589 um PUBCHEM_BIOASSAY: qHTS Screen for Compounds that Selectively Target Cancer Cells with p53 Mutations: Cytotoxicity of p53ts Cells at the Permissive Temperature. (Class of assay: confirmatory) [Related pubchem assays: 902 ] ChEMBL. No reference
Potency (functional) = 6.3096 um PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Thyroid Stimulating Hormone Receptor. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) = 6.3096 um PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Thyroid Stimulating Hormone Receptor: Activators of Intracellular cAMP Concentrations in Parental HEK 293. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) = 8.9125 um PUBCHEM_BIOASSAY: qHTS Assay for Inhibitors of 12-hLO (12-human lipoxygenase). (Class of assay: confirmatory) ChEMBL. No reference

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

Bibliographic References

No literature references available for this target.

If you have references for this compound, please enter them in a user comment (below) or Contact us.