Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Loa Loa (eye worm) | hypothetical protein | 0.0039 | 0.1343 | 0.1743 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0019 | 0.0517 | 0.0906 |
Schistosoma mansoni | blooms syndrome DNA helicase | 0.0019 | 0.0531 | 0.0742 |
Brugia malayi | beta-lactamase | 0.0039 | 0.1343 | 0.1743 |
Brugia malayi | hypothetical protein | 0.0165 | 0.6546 | 0.8564 |
Giardia lamblia | Nuclear LIM interactor-interacting factor 1 | 0.0013 | 0.0257 | 0.0499 |
Toxoplasma gondii | Dullard family phosphatase domain-containing protein | 0.0013 | 0.0257 | 0.0354 |
Brugia malayi | regulator of G-protein signaling egl-10 | 0.0009 | 0.0125 | 0.0146 |
Giardia lamblia | Endonuclease/Exonuclease/phosphatase | 0.0019 | 0.0525 | 0.1777 |
Trichomonas vaginalis | nuclear lim interactor-interacting factor, putative | 0.0013 | 0.0257 | 0.1086 |
Mycobacterium tuberculosis | Possible DNA-damage-inducible protein P DinP (DNA polymerase V) (pol IV 2) (DNA nucleotidyltransferase (DNA-directed)) | 0.0061 | 0.2252 | 0.1822 |
Echinococcus granulosus | dna polymerase eta | 0.0142 | 0.5572 | 0.7782 |
Loa Loa (eye worm) | exodeoxyribonuclease III family protein | 0.0019 | 0.0525 | 0.067 |
Trypanosoma brucei | DNA polymerase IV, putative | 0.0061 | 0.2252 | 0.3753 |
Echinococcus multilocularis | bloom syndrome protein | 0.0024 | 0.0743 | 0.1021 |
Echinococcus granulosus | regulator of G protein signaling 7 | 0.0009 | 0.0125 | 0.0156 |
Echinococcus multilocularis | beta LACTamase domain containing family member | 0.0039 | 0.1343 | 0.1861 |
Loa Loa (eye worm) | hypothetical protein | 0.0039 | 0.1343 | 0.1743 |
Echinococcus granulosus | bloom syndrome protein | 0.0024 | 0.0743 | 0.1021 |
Brugia malayi | Domain found in Dishevelled, Egl-10, and Pleckstrin family protein | 0.0009 | 0.0125 | 0.0146 |
Entamoeba histolytica | exodeoxyribonuclease III, putative | 0.0019 | 0.0525 | 0.2053 |
Echinococcus granulosus | regulator of G protein signaling 7 | 0.0009 | 0.0125 | 0.0156 |
Loa Loa (eye worm) | hypothetical protein | 0.008 | 0.3016 | 0.3936 |
Toxoplasma gondii | exonuclease III APE | 0.0019 | 0.0525 | 0.1077 |
Loa Loa (eye worm) | beta-LACTamase domain containing family member | 0.0039 | 0.1343 | 0.1743 |
Brugia malayi | Carboxy-terminal domain RNA polymerase II polypeptide A smallphosphatase 1 | 0.0013 | 0.0257 | 0.0319 |
Echinococcus multilocularis | Pleckstrin G protein, interacting region | 0.0009 | 0.0125 | 0.0156 |
Plasmodium vivax | DNA repair protein REV1, putative | 0.0019 | 0.0517 | 0.0944 |
Schistosoma mansoni | hypothetical protein | 0.018 | 0.7156 | 1 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0019 | 0.0517 | 0.049 |
Trichomonas vaginalis | D-aminoacylase, putative | 0.0039 | 0.1343 | 0.5939 |
Trypanosoma cruzi | ATP-dependent DEAD/H DNA helicase recQ, putative | 0.0013 | 0.0274 | 0.0469 |
Brugia malayi | ATP-dependent DNA helicase, RecQ family protein | 0.001 | 0.0152 | 0.0181 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0061 | 0.2252 | 0.3753 |
Loa Loa (eye worm) | hypothetical protein | 0.001 | 0.0152 | 0.0181 |
Trypanosoma cruzi | tyrosyl-DNA Phosphodiesterase (Tdp1), putative | 0.0067 | 0.2504 | 0.4481 |
Echinococcus multilocularis | regulator of G protein signaling 7 | 0.0009 | 0.0125 | 0.0156 |
Onchocerca volvulus | 0.0165 | 0.6546 | 0.8564 | |
Echinococcus multilocularis | dna polymerase eta | 0.0142 | 0.5572 | 0.7782 |
Echinococcus multilocularis | peptidase Clp (S14 family) | 0.0052 | 0.1886 | 0.2621 |
Trypanosoma brucei | unspecified product | 0.0061 | 0.2252 | 0.3753 |
Mycobacterium tuberculosis | Conserved protein | 0.0039 | 0.1343 | 0.0863 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0061 | 0.2252 | 0.3753 |
Plasmodium vivax | hypothetical protein, conserved | 0.0039 | 0.1343 | 0.3937 |
Echinococcus multilocularis | transcription factor Dp 1 | 0.0039 | 0.1339 | 0.1855 |
Brugia malayi | polk-prov protein | 0.0019 | 0.0517 | 0.066 |
Trypanosoma brucei | hypothetical protein, conserved | 0.0039 | 0.1343 | 0.2043 |
Echinococcus multilocularis | Carboxy terminal domain RNA polymerase II | 0.0013 | 0.0257 | 0.034 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0042 | 0.1471 | 0.2285 |
Loa Loa (eye worm) | hypothetical protein | 0.0192 | 0.7641 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0039 | 0.1343 | 0.1743 |
Mycobacterium ulcerans | beta-lactamase | 0.0039 | 0.1343 | 0.3305 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0042 | 0.1471 | 0.2285 |
Brugia malayi | N-terminal motif family protein | 0.0192 | 0.7641 | 1 |
Trypanosoma cruzi | DNA damage repair protein, putative | 0.0019 | 0.0517 | 0.0906 |
Trypanosoma cruzi | DNA polymerase eta, putative | 0.01 | 0.3837 | 0.6879 |
Schistosoma mansoni | ras GTP exchange factor son of sevenless | 0.0007 | 0.0014 | 0.0019 |
Loa Loa (eye worm) | hypothetical protein | 0.0012 | 0.025 | 0.031 |
Trichomonas vaginalis | dullard protein, putative | 0.0013 | 0.0257 | 0.1086 |
Mycobacterium leprae | Probable lipase LipE | 0.0039 | 0.1343 | 0.2218 |
Trichomonas vaginalis | nuclear lim interactor-interacting factor, putative | 0.0013 | 0.0257 | 0.1086 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0039 | 0.1343 | 0.2391 |
Mycobacterium tuberculosis | Probable esterase LipL | 0.0039 | 0.1343 | 0.0863 |
Toxoplasma gondii | hypothetical protein | 0.0027 | 0.0866 | 0.1996 |
Echinococcus granulosus | CTD small phosphatase protein like | 0.0013 | 0.0257 | 0.034 |
Echinococcus multilocularis | 0.0013 | 0.0257 | 0.034 | |
Trichomonas vaginalis | dullard protein, putative | 0.0013 | 0.0257 | 0.1086 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0013 | 0.0257 | 0.0437 |
Trypanosoma brucei | DNA polymerase eta, putative | 0.0142 | 0.5572 | 1 |
Treponema pallidum | ATP-dependent Clp protease proteolytic subunit | 0.008 | 0.3016 | 1 |
Mycobacterium tuberculosis | Conserved protein | 0.0039 | 0.1343 | 0.0863 |
Trichomonas vaginalis | ap endonuclease, putative | 0.0019 | 0.0525 | 0.2285 |
Brugia malayi | Bloom's syndrome protein homolog | 0.0024 | 0.0743 | 0.0956 |
Brugia malayi | ImpB/MucB/SamB family protein | 0.0142 | 0.5572 | 0.7287 |
Chlamydia trachomatis | ATP-dependent Clp protease proteolytic subunit | 0.008 | 0.3016 | 0.5 |
Plasmodium falciparum | ATP-dependent Clp protease proteolytic subunit | 0.0027 | 0.0866 | 0.2494 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0061 | 0.2252 | 0.3753 |
Loa Loa (eye worm) | ImpB/MucB/SamB family protein | 0.0061 | 0.2252 | 0.2934 |
Leishmania major | DNA polymerase kappa, putative | 0.0061 | 0.2252 | 0.3753 |
Mycobacterium ulcerans | exodeoxyribonuclease III protein XthA | 0.0019 | 0.0525 | 0.0032 |
Trypanosoma brucei | ATP-dependent DEAD/H DNA helicase recQ, putative | 0.0013 | 0.0274 | 0.0033 |
Schistosoma mansoni | hypothetical protein | 0.018 | 0.7156 | 1 |
Trypanosoma cruzi | DNA damage repair protein, putative | 0.0019 | 0.0517 | 0.0906 |
Mycobacterium ulcerans | DNA polymerase IV | 0.0061 | 0.2252 | 0.6943 |
Trypanosoma brucei | DNA damage repair protein, putative | 0.0019 | 0.0517 | 0.049 |
Plasmodium falciparum | ADP-dependent DNA helicase RecQ | 0.0021 | 0.0621 | 0.1637 |
Trypanosoma cruzi | apurinic/apyrimidinic endonuclease, putative | 0.0019 | 0.0525 | 0.092 |
Schistosoma mansoni | DNA helicase recq1 | 0.001 | 0.0152 | 0.0212 |
Chlamydia trachomatis | ATP-dependent Clp protease proteolytic subunit | 0.008 | 0.3016 | 0.5 |
Trichomonas vaginalis | esterase, putative | 0.0039 | 0.1343 | 0.5939 |
Toxoplasma gondii | ATP-dependent DNA helicase, RecQ family protein | 0.0016 | 0.0409 | 0.0764 |
Mycobacterium leprae | conserved hypothetical protein | 0.0039 | 0.1343 | 0.2218 |
Echinococcus multilocularis | regulator of G protein signaling 7 | 0.0009 | 0.0125 | 0.0156 |
Onchocerca volvulus | Segment polarity protein dishevelled homolog | 0.0009 | 0.0125 | 0.0146 |
Loa Loa (eye worm) | hypothetical protein | 0.0039 | 0.1343 | 0.1743 |
Echinococcus granulosus | tyrosyl DNA phosphodiesterase 1 | 0.0067 | 0.2504 | 0.3487 |
Giardia lamblia | DINP protein human, muc B family | 0.0061 | 0.2252 | 1 |
Leishmania major | tyrosyl-DNA phosphodiesterase 1 | 0.0067 | 0.2504 | 0.4229 |
Mycobacterium tuberculosis | Probable hydrolase | 0.0039 | 0.1343 | 0.0863 |
Onchocerca volvulus | 0.0039 | 0.1343 | 0.1743 | |
Echinococcus granulosus | ATP dependent Clp protease proteolytic subunit | 0.008 | 0.3016 | 0.4203 |
Trichomonas vaginalis | DNA polymerase IV / kappa, putative | 0.0061 | 0.2252 | 1 |
Loa Loa (eye worm) | beta-lactamase | 0.0039 | 0.1343 | 0.1743 |
Schistosoma mansoni | family S12 unassigned peptidase (S12 family) | 0.0039 | 0.1343 | 0.1876 |
Mycobacterium ulcerans | esterase/lipase LipP | 0.0039 | 0.1343 | 0.3305 |
Trypanosoma brucei | DNA damage repair protein, putative | 0.0019 | 0.0517 | 0.049 |
Entamoeba histolytica | tyrosyl-DNA phosphodiesterase, putative | 0.0067 | 0.2504 | 1 |
Schistosoma mansoni | dep domain containing protein | 0.0009 | 0.0125 | 0.0175 |
Loa Loa (eye worm) | hypothetical protein | 0.0019 | 0.0517 | 0.066 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0042 | 0.1471 | 0.2285 |
Trichomonas vaginalis | DNA helicase recq, putative | 0.0013 | 0.0274 | 0.1164 |
Trichomonas vaginalis | nuclear lim interactor-interacting factor, putative | 0.0013 | 0.0257 | 0.1086 |
Schistosoma mansoni | nuclear lim interactor-interacting factor (nli-interacting factor) (nli-if) | 0.0013 | 0.0257 | 0.0359 |
Echinococcus granulosus | Carboxy terminal domain RNA polymerase II | 0.0013 | 0.0257 | 0.034 |
Mycobacterium tuberculosis | Probable ATP-dependent CLP protease proteolytic subunit 1 ClpP1 (endopeptidase CLP) | 0.0052 | 0.1886 | 0.1436 |
Mycobacterium ulcerans | ATP-dependent Clp protease proteolytic subunit | 0.008 | 0.3016 | 1 |
Onchocerca volvulus | 0.0039 | 0.1343 | 0.1743 | |
Trypanosoma cruzi | DNA polymerase kappa, putative | 0.0061 | 0.2252 | 0.4027 |
Brugia malayi | exodeoxyribonuclease III family protein | 0.0019 | 0.0525 | 0.067 |
Trypanosoma cruzi | tyrosyl-DNA Phosphodiesterase (Tdp1), putative | 0.0067 | 0.2504 | 0.4481 |
Mycobacterium tuberculosis | Probable conserved lipoprotein | 0.0039 | 0.1343 | 0.0863 |
Brugia malayi | ImpB/MucB/SamB family protein | 0.0061 | 0.2252 | 0.2934 |
Loa Loa (eye worm) | G protein signaling regulator EGL-10 | 0.0009 | 0.0125 | 0.0146 |
Wolbachia endosymbiont of Brugia malayi | ATP-dependent Clp protease proteolytic subunit | 0.008 | 0.3016 | 1 |
Brugia malayi | hypothetical protein | 0.0009 | 0.0125 | 0.0146 |
Loa Loa (eye worm) | hypothetical protein | 0.0123 | 0.4803 | 0.628 |
Mycobacterium ulcerans | lipase LipD | 0.0039 | 0.1343 | 0.3305 |
Brugia malayi | Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative | 0.0039 | 0.1343 | 0.1743 |
Echinococcus multilocularis | dna polymerase kappa | 0.0061 | 0.2252 | 0.3134 |
Schistosoma mansoni | ap endonuclease | 0.0019 | 0.0525 | 0.0733 |
Trichomonas vaginalis | penicillin-binding protein, putative | 0.0039 | 0.1343 | 0.5939 |
Plasmodium vivax | ATP-dependent Clp protease proteolytic subunit, putative | 0.0027 | 0.0866 | 0.2209 |
Brugia malayi | Domain found in Dishevelled, Egl-10, and Pleckstrin family protein | 0.0009 | 0.0125 | 0.0146 |
Trypanosoma cruzi | apurinic/apyrimidinic endonuclease | 0.0019 | 0.0525 | 0.092 |
Brugia malayi | Probable ClpP-like protease | 0.008 | 0.3016 | 0.3936 |
Trypanosoma cruzi | DNA polymerase kappa, putative | 0.0061 | 0.2252 | 0.4027 |
Mycobacterium ulcerans | hypothetical protein | 0.0039 | 0.1343 | 0.3305 |
Echinococcus multilocularis | tyrosyl DNA phosphodiesterase 1 | 0.0067 | 0.2504 | 0.3487 |
Echinococcus granulosus | dna polymerase kappa | 0.0061 | 0.2252 | 0.3134 |
Schistosoma mansoni | ras GTP exchange factor son of sevenless | 0.0007 | 0.0014 | 0.0019 |
Loa Loa (eye worm) | DIX domain-containing protein | 0.0009 | 0.0125 | 0.0146 |
Schistosoma mansoni | DNA polymerase eta | 0.0142 | 0.5572 | 0.7786 |
Leishmania major | DNA damage repair protein, putative | 0.0019 | 0.0517 | 0.049 |
Trypanosoma cruzi | DNA polymerase kappa, putative | 0.0061 | 0.2252 | 0.4027 |
Mycobacterium tuberculosis | Probable esterase/lipase LipP | 0.0039 | 0.1343 | 0.0863 |
Schistosoma mansoni | DNA polymerase IV / kappa | 0.0019 | 0.0517 | 0.0722 |
Schistosoma mansoni | guanine-nucleotide-exchange-factor | 0.0007 | 0.0014 | 0.0019 |
Mycobacterium tuberculosis | Conserved hypothetical protein | 0.0061 | 0.2252 | 0.1822 |
Echinococcus granulosus | terminal deoxycytidyl transferase rev1 | 0.0061 | 0.2252 | 0.3134 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0061 | 0.2252 | 0.3753 |
Mycobacterium leprae | PROBABLE ATP-DEPENDENT CLP PROTEASE PROTEOLYTIC SUBUNIT 2 CLPP2 (ENDOPEPTIDASE CLP 2) | 0.008 | 0.3016 | 1 |
Plasmodium falciparum | AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative | 0.0019 | 0.0525 | 0.1303 |
Leishmania major | DNA polymerase kappa, putative,DNA polymerase IV, putative | 0.0061 | 0.2252 | 0.3753 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0039 | 0.1343 | 0.2391 |
Trypanosoma brucei | hypothetical protein, conserved | 0.0019 | 0.0517 | 0.049 |
Schistosoma mansoni | DNA helicase recq5 | 0.001 | 0.0152 | 0.0212 |
Schistosoma mansoni | regulator of G protein signaling | 0.0009 | 0.0125 | 0.0175 |
Brugia malayi | ATP-dependent DNA helicase, RecQ family protein | 0.001 | 0.0152 | 0.0181 |
Loa Loa (eye worm) | hypothetical protein | 0.0009 | 0.0125 | 0.0146 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0061 | 0.2252 | 0.3753 |
Trypanosoma cruzi | DNA polymerase eta, putative | 0.0142 | 0.5572 | 1 |
Mycobacterium tuberculosis | Probable lipase LipD | 0.0039 | 0.1343 | 0.0863 |
Schistosoma mansoni | hypothetical protein | 0.0012 | 0.025 | 0.035 |
Trichomonas vaginalis | D-aminoacylase, putative | 0.0039 | 0.1343 | 0.5939 |
Toxoplasma gondii | ATP-dependent Clp endopeptidase, proteolytic subunit ClpP domain-containing protein | 0.008 | 0.3016 | 0.7787 |
Mycobacterium tuberculosis | Probable ATP-dependent CLP protease proteolytic subunit 2 ClpP2 (endopeptidase CLP 2) | 0.0052 | 0.1886 | 0.1436 |
Toxoplasma gondii | ImpB/MucB/SamB family protein | 0.0019 | 0.0517 | 0.1055 |
Echinococcus multilocularis | ATP dependent DNA helicase Q1 | 0.001 | 0.0152 | 0.0193 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0019 | 0.0517 | 0.0906 |
Echinococcus multilocularis | segment polarity protein dishevelled | 0.0009 | 0.0125 | 0.0156 |
Toxoplasma gondii | ABC1 family protein | 0.0039 | 0.1343 | 0.328 |
Leishmania major | ATP-dependent DEAD/H DNA helicase recQ, putative | 0.0013 | 0.0274 | 0.0033 |
Plasmodium vivax | ADP-dependent DNA helicase RecQ, putative | 0.0017 | 0.0417 | 0.0581 |
Leishmania major | hypothetical protein, conserved | 0.0039 | 0.1343 | 0.2043 |
Toxoplasma gondii | ImpB/MucB/SamB family protein | 0.01 | 0.3837 | 1 |
Loa Loa (eye worm) | ATP-dependent DNA helicase | 0.001 | 0.0152 | 0.0181 |
Trichomonas vaginalis | D-aminoacylase, putative | 0.0039 | 0.1343 | 0.5939 |
Loa Loa (eye worm) | hypothetical protein | 0.0009 | 0.0125 | 0.0146 |
Onchocerca volvulus | Rap guanine nucleotide exchange factor 1 homolog | 0.0192 | 0.7641 | 1 |
Schistosoma mansoni | ras GTP exchange factor | 0.0007 | 0.0014 | 0.0019 |
Brugia malayi | beta-lactamase family protein | 0.0039 | 0.1343 | 0.1743 |
Echinococcus granulosus | ATP dependent DNA helicase Q5 | 0.001 | 0.0152 | 0.0193 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0061 | 0.2252 | 0.3753 |
Schistosoma mansoni | dishevelled | 0.0009 | 0.0125 | 0.0175 |
Echinococcus granulosus | DNA apurinic or apyrimidinic site lyase | 0.0019 | 0.0525 | 0.0716 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0061 | 0.2252 | 0.3753 |
Schistosoma mansoni | family S12 unassigned peptidase (S12 family) | 0.0039 | 0.1343 | 0.1876 |
Echinococcus granulosus | peptidase Clp S14 family | 0.0052 | 0.1886 | 0.2621 |
Onchocerca volvulus | 0.0039 | 0.1343 | 0.1743 | |
Leishmania major | DNA polymerase eta, putative | 0.01 | 0.3837 | 0.6736 |
Toxoplasma gondii | ATP-dependent DNA helicase, RecQ family protein | 0.001 | 0.0152 | 0.0071 |
Toxoplasma gondii | BRCA1 C Terminus (BRCT) domain-containing protein | 0.0019 | 0.0517 | 0.1055 |
Leishmania major | apurinic/apyrimidinic endonuclease-redox protein | 0.0019 | 0.0525 | 0.0505 |
Trichomonas vaginalis | dullard protein, putative | 0.0013 | 0.0257 | 0.1086 |
Trypanosoma brucei | DNA polymerase IV, putative | 0.0061 | 0.2252 | 0.3753 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0019 | 0.0517 | 0.049 |
Echinococcus granulosus | ATP dependent DNA helicase Q1 | 0.001 | 0.0152 | 0.0193 |
Echinococcus granulosus | beta LACTamase domain containing family member | 0.0039 | 0.1343 | 0.1861 |
Plasmodium falciparum | NLI interacting factor-like phosphatase, putative | 0.0013 | 0.0257 | 0.0366 |
Echinococcus multilocularis | DNA (apurinic or apyrimidinic site) lyase | 0.0019 | 0.0525 | 0.0716 |
Brugia malayi | Tyrosyl-DNA phosphodiesterase family protein | 0.0067 | 0.2504 | 0.3266 |
Loa Loa (eye worm) | RecQ helicase | 0.0024 | 0.0743 | 0.0956 |
Toxoplasma gondii | ATP-dependent Clp endopeptidase, proteolytic subunit ClpP domain-containing protein | 0.008 | 0.3016 | 0.7787 |
Leishmania major | DNA polymerase kappa, putative | 0.0019 | 0.0517 | 0.049 |
Loa Loa (eye worm) | hypothetical protein | 0.0039 | 0.1343 | 0.1743 |
Echinococcus multilocularis | ATP dependent DNA helicase Q5 | 0.001 | 0.0152 | 0.0193 |
Trypanosoma cruzi | DNA polymerase kappa, putative | 0.0061 | 0.2252 | 0.4027 |
Echinococcus granulosus | segment polarity protein dishevelled | 0.0009 | 0.0125 | 0.0156 |
Trypanosoma brucei | tyrosyl-DNA Phosphodiesterase (Tdp1), putative | 0.0067 | 0.2504 | 0.4229 |
Echinococcus multilocularis | terminal deoxycytidyl transferase rev1 | 0.0061 | 0.2252 | 0.3134 |
Loa Loa (eye worm) | hypothetical protein | 0.0165 | 0.6546 | 0.8564 |
Giardia lamblia | DNA damage repair protein | 0.0019 | 0.0517 | 0.1739 |
Trichomonas vaginalis | DNA helicase recq1, putative | 0.0024 | 0.0743 | 0.3259 |
Trypanosoma brucei | apurinic/apyrimidinic endonuclease, putative | 0.0019 | 0.0525 | 0.0505 |
Schistosoma mansoni | rab geranylgeranyl transferase alpha subunit | 0.0061 | 0.2252 | 0.3147 |
Schistosoma mansoni | peptidase Clp (S14 family) | 0.008 | 0.3016 | 0.4214 |
Schistosoma mansoni | ap endonuclease | 0.0019 | 0.0525 | 0.0733 |
Mycobacterium ulcerans | DNA polymerase IV | 0.0061 | 0.2252 | 0.6943 |
Plasmodium falciparum | ATP-dependent Clp protease proteolytic subunit | 0.008 | 0.3016 | 1 |
Trichomonas vaginalis | DNA polymerase eta, putative | 0.0061 | 0.2252 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0039 | 0.1343 | 0.1743 |
Schistosoma mansoni | dishevelled | 0.0009 | 0.0125 | 0.0175 |
Treponema pallidum | ATP-dependent Clp protease proteolytic subunit | 0.0027 | 0.0866 | 0.137 |
Schistosoma mansoni | ras GTP exchange factor son of sevenless | 0.0007 | 0.0014 | 0.0019 |
Entamoeba histolytica | recQ family helicase, putative | 0.0013 | 0.0274 | 0.1046 |
Leishmania major | DNA polymerase eta, putative | 0.0142 | 0.5572 | 1 |
Schistosoma mansoni | nuclear lim interactor-interacting factor (nli-interacting factor) (nli-if) | 0.0013 | 0.0257 | 0.0359 |
Mycobacterium tuberculosis | Possible conserved lipoprotein LpqK | 0.0039 | 0.1343 | 0.0863 |
Trypanosoma brucei | unspecified product | 0.0042 | 0.1471 | 0.2285 |
Echinococcus multilocularis | segment polarity protein dishevelled | 0.0009 | 0.0125 | 0.0156 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0061 | 0.2252 | 0.3753 |
Trichomonas vaginalis | DNA helicase recq, putative | 0.0024 | 0.0743 | 0.3259 |
Entamoeba histolytica | deoxycytidyl transferase, putative | 0.0061 | 0.2252 | 0.8985 |
Mycobacterium ulcerans | ATP-dependent Clp protease proteolytic subunit | 0.008 | 0.3016 | 1 |
Echinococcus granulosus | transcription factor Dp 1 | 0.0039 | 0.1339 | 0.1855 |
Schistosoma mansoni | fyve finger-containing phosphoinositide kinase fyv1 | 0.0009 | 0.0125 | 0.0175 |
Trypanosoma brucei | hypothetical protein, conserved | 0.0019 | 0.0517 | 0.049 |
Mycobacterium tuberculosis | Conserved protein | 0.0039 | 0.1343 | 0.0863 |
Plasmodium vivax | AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative | 0.0019 | 0.0525 | 0.0973 |
Trypanosoma brucei | DNA polymerase IV, putative | 0.0061 | 0.2252 | 0.3753 |
Brugia malayi | beta-lactamase family protein | 0.0039 | 0.1343 | 0.1743 |
Trypanosoma brucei | unspecified product | 0.0042 | 0.1471 | 0.2285 |
Schistosoma mansoni | tyrosyl-DNA phosphodiesterase | 0.0067 | 0.2504 | 0.35 |
Trichomonas vaginalis | penicillin-binding protein, putative | 0.0039 | 0.1343 | 0.5939 |
Loa Loa (eye worm) | tyrosyl-DNA phosphodiesterase | 0.0067 | 0.2504 | 0.3266 |
Loa Loa (eye worm) | hypothetical protein | 0.0013 | 0.0257 | 0.0319 |
Echinococcus granulosus | geminin | 0.018 | 0.7156 | 1 |
Schistosoma mansoni | z-protein (S1r protein) | 0.0009 | 0.0125 | 0.0175 |
Mycobacterium tuberculosis | Probable lipase LipE | 0.0039 | 0.1343 | 0.0863 |
Trichomonas vaginalis | nuclear lim interactor-interacting factor, putative | 0.0013 | 0.0257 | 0.1086 |
Brugia malayi | hypothetical protein | 0.0009 | 0.0125 | 0.0146 |
Loa Loa (eye worm) | hypothetical protein | 0.0009 | 0.0125 | 0.0146 |
Brugia malayi | DIX domain containing protein | 0.0009 | 0.0125 | 0.0146 |
Echinococcus granulosus | segment polarity protein dishevelled | 0.0009 | 0.0125 | 0.0156 |
Trichomonas vaginalis | ap endonuclease, putative | 0.0019 | 0.0525 | 0.2285 |
Plasmodium vivax | ATP-dependent Clp protease proteolytic subunit, putative | 0.008 | 0.3016 | 1 |
Entamoeba histolytica | NLI interacting factor-like phosphatase domain-containing protein | 0.0013 | 0.0257 | 0.0976 |
Echinococcus multilocularis | geminin | 0.018 | 0.7156 | 1 |
Mycobacterium leprae | PROBABLE ATP-DEPENDENT CLP PROTEASE PROTEOLYTIC SUBUNIT 1 CLPP1 (ENDOPEPTIDASE CLP) | 0.0052 | 0.1886 | 0.4744 |
Onchocerca volvulus | 0.0009 | 0.0125 | 0.0146 | |
Mycobacterium ulcerans | fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE | 0.0039 | 0.1343 | 0.3305 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0061 | 0.2252 | 0.3753 |
Toxoplasma gondii | ATP-dependent DNA helicase, RecQ family protein | 0.001 | 0.0152 | 0.0071 |
Schistosoma mansoni | terminal deoxycytidyl transferase | 0.0061 | 0.2252 | 0.3147 |
Plasmodium falciparum | DNA repair protein REV1, putative | 0.0019 | 0.0517 | 0.1275 |
Echinococcus granulosus | Pleckstrin G protein interacting region | 0.0009 | 0.0125 | 0.0156 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0061 | 0.2252 | 0.3753 |
Trypanosoma brucei | chrX additional, unordered contigs | 0.0019 | 0.0517 | 0.049 |
Loa Loa (eye worm) | hypothetical protein | 0.0142 | 0.5572 | 0.7287 |
Echinococcus multilocularis | ATP dependent Clp protease proteolytic subunit | 0.008 | 0.3016 | 0.4203 |
Activity type | Activity value | Assay description | Source | Reference |
---|---|---|---|---|
Potency (functional) | 39.8107 uM | PubChem BioAssay. qHTS of PTHR Inhibitors: Primary Screen. (Class of assay: confirmatory) | ChEMBL. | No reference |
Potency (functional) | 100 uM | PUBCHEM_BIOASSAY: Inhibitors of TCP-1 ring complex (TRiC) of Methanococcus maripaludis (MmCpn): qHTS. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID488991] | ChEMBL. | No reference |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.