Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Schistosoma mansoni | cpg binding protein | 0.0034 | 0.4688 | 0.4688 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0007 | 0.0542 | 1 |
Brugia malayi | CXXC zinc finger family protein | 0.0032 | 0.4403 | 1 |
Schistosoma mansoni | cpg binding protein | 0.0034 | 0.4688 | 0.4688 |
Loa Loa (eye worm) | CXXC zinc finger family protein | 0.0032 | 0.4403 | 1 |
Onchocerca volvulus | 0.0032 | 0.4403 | 0.5 | |
Schistosoma mansoni | cpg binding protein | 0.0032 | 0.4403 | 0.4403 |
Echinococcus granulosus | cpg binding protein | 0.0034 | 0.4688 | 1 |
Entamoeba histolytica | hypothetical protein | 0.0004 | 0 | 0.5 |
Trichomonas vaginalis | chromodomain helicase DNA binding protein, putative | 0.0007 | 0.0542 | 1 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0007 | 0.0542 | 1 |
Trichomonas vaginalis | chromodomain helicase DNA binding protein, putative | 0.0007 | 0.0542 | 1 |
Schistosoma mansoni | mixed-lineage leukemia protein mll | 0.0008 | 0.0651 | 0.0651 |
Echinococcus multilocularis | cpg binding protein | 0.0034 | 0.4688 | 1 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0007 | 0.0542 | 1 |
Echinococcus multilocularis | histone lysine N methyltransferase MLL3 | 0.001 | 0.0956 | 0.0754 |
Plasmodium falciparum | zinc finger protein, putative | 0.0004 | 0 | 0.5 |
Echinococcus granulosus | histone lysine N methyltransferase MLL3 | 0.001 | 0.0956 | 0.0754 |
Trichomonas vaginalis | chromodomain helicase DNA binding protein, putative | 0.0007 | 0.0542 | 1 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0007 | 0.0542 | 1 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0007 | 0.0542 | 1 |
Trichomonas vaginalis | chromodomain helicase DNA binding protein, putative | 0.0007 | 0.0542 | 1 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0007 | 0.0542 | 1 |
Trichomonas vaginalis | chromodomain helicase DNA binding protein, putative | 0.0007 | 0.0542 | 1 |
Toxoplasma gondii | histone lysine methyltransferase SET1 | 0.0061 | 0.8869 | 0.5 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0007 | 0.0542 | 1 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0007 | 0.0542 | 1 |
Trichomonas vaginalis | chromodomain-helicase-DNA-binding protein, putative | 0.0007 | 0.0542 | 1 |
Trichomonas vaginalis | helicase, putative | 0.0007 | 0.0542 | 1 |
Trichomonas vaginalis | chromodomain helicase DNA binding protein, putative | 0.0007 | 0.0542 | 1 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0007 | 0.0542 | 1 |
Schistosoma mansoni | mixed-lineage leukemia protein mll | 0.0005 | 0.0127 | 0.0127 |
Trichomonas vaginalis | chromodomain-helicase-DNA-binding protein, putative | 0.0007 | 0.0542 | 1 |
Activity type | Activity value | Assay description | Source | Reference |
---|---|---|---|---|
Potency (functional) | 0.6573 uM | PUBCHEM_BIOASSAY: Primary qHTS for delayed death inhibitors of the malarial parasite plastid, 48 hour incubation. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID488752, AID488774, AID504848, AID504850] | ChEMBL. | No reference |
Species name | Source | Reference | Is orphan |
---|---|---|---|
Plasmodium falciparum | ChEMBL23 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.