Detailed information for compound 1297817

Basic information

Technical information
  • TDR Targets ID: 1297817
  • Name: N-cyclohexyl-4-[[2-(phenylmethylsulfanyl)imid azo[5,4-b]pyridin-3-yl]methyl]benzamide
  • MW: 456.602 | Formula: C27H28N4OS
  • H donors: 1 H acceptors: 3 LogP: 5.72 Rotable bonds: 8
    Rule of 5 violations (Lipinski): 1
  • SMILES: O=C(c1ccc(cc1)Cn1c(SCc2ccccc2)nc2c1nccc2)NC1CCCCC1
  • InChi: 1S/C27H28N4OS/c32-26(29-23-10-5-2-6-11-23)22-15-13-20(14-16-22)18-31-25-24(12-7-17-28-25)30-27(31)33-19-21-8-3-1-4-9-21/h1,3-4,7-9,12-17,23H,2,5-6,10-11,18-19H2,(H,29,32)
  • InChiKey: AXYVFXRWEMSECD-UHFFFAOYSA-N  

Network

Hover on a compound node to display the structore

Synonyms

  • N-cyclohexyl-4-[[2-(phenylmethylthio)-3-imidazo[5,4-b]pyridinyl]methyl]benzamide
  • 4-[[2-(benzylthio)imidazo[5,4-b]pyridin-3-yl]methyl]-N-cyclohexyl-benzamide
  • E642-0900
  • NCGC00124118-01

Targets

Known targets for this compound

Species Target name Source Bibliographic reference
Bacillus subtilis (strain 168) ATP-dependent Clp protease proteolytic subunit Starlite/ChEMBL No references
Homo sapiens SMAD family member 2 Starlite/ChEMBL No references
Photinus pyralis Luciferin 4-monooxygenase Starlite/ChEMBL No references
Schistosoma mansoni Thioredoxin glutathione reductase Starlite/ChEMBL No references

Predicted pathogen targets for this compound

By orthology
Species Potential target Known druggable target/s Ortholog Group
Mycobacterium tuberculosis Probable ATP-dependent CLP protease proteolytic subunit 2 ClpP2 (endopeptidase CLP 2) Get druggable targets OG5_127187 All targets in OG5_127187
Trypanosoma brucei trypanothione reductase Get druggable targets OG5_126785 All targets in OG5_126785
Echinococcus granulosus ATP dependent Clp protease proteolytic subunit Get druggable targets OG5_127187 All targets in OG5_127187
Toxoplasma gondii ATP-dependent Clp endopeptidase, proteolytic subunit ClpP domain-containing protein Get druggable targets OG5_127187 All targets in OG5_127187
Echinococcus granulosus peptidase Clp S14 family Get druggable targets OG5_127187 All targets in OG5_127187
Leishmania braziliensis trypanothione reductase Get druggable targets OG5_126785 All targets in OG5_126785
Plasmodium knowlesi ATP-dependent Clp protease proteolytic subunit, putative Get druggable targets OG5_127187 All targets in OG5_127187
Plasmodium falciparum glutathione reductase Get druggable targets OG5_126785 All targets in OG5_126785
Mycobacterium tuberculosis Fatty-acid-AMP ligase FadD30 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) Get druggable targets OG5_126609 All targets in OG5_126609
Echinococcus multilocularis peptidase Clp (S14 family) Get druggable targets OG5_127187 All targets in OG5_127187
Plasmodium falciparum thioredoxin reductase Get druggable targets OG5_126785 All targets in OG5_126785
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_126609 All targets in OG5_126609
Theileria parva thioredoxin reductase, putative Get druggable targets OG5_126785 All targets in OG5_126785
Trypanosoma cruzi trypanothione reductase, putative Get druggable targets OG5_126785 All targets in OG5_126785
Treponema pallidum ATP-dependent Clp protease proteolytic subunit Get druggable targets OG5_127187 All targets in OG5_127187
Echinococcus multilocularis ATP dependent Clp protease proteolytic subunit Get druggable targets OG5_127187 All targets in OG5_127187
Plasmodium knowlesi thioredoxin reductase, putative Get druggable targets OG5_126785 All targets in OG5_126785
Leishmania major 4-coumarate:coa ligase-like protein Get druggable targets OG5_126609 All targets in OG5_126609
Plasmodium falciparum acyl-CoA synthetase Get druggable targets OG5_126609 All targets in OG5_126609
Mycobacterium tuberculosis Probable ATP-dependent CLP protease proteolytic subunit 1 ClpP1 (endopeptidase CLP) Get druggable targets OG5_127187 All targets in OG5_127187
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD7 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) Get druggable targets OG5_126609 All targets in OG5_126609
Theileria parva ATP-dependent Clp protease proteolytic subunit, putative Get druggable targets OG5_127187 All targets in OG5_127187
Echinococcus granulosus thioredoxin glutathione reductase Get druggable targets OG5_126785 All targets in OG5_126785
Leishmania mexicana 4-coumarate:coa ligase-like protein Get druggable targets OG5_126609 All targets in OG5_126609
Schistosoma japonicum ko:K01358 ATP-dependent Clp protease, protease subunit [EC3.4.21.92], putative Get druggable targets OG5_127187 All targets in OG5_127187
Loa Loa (eye worm) transcription factor SMAD2 Get druggable targets OG5_131716 All targets in OG5_131716
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD3 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) Get druggable targets OG5_126609 All targets in OG5_126609
Leishmania mexicana trypanothione reductase Get druggable targets OG5_126785 All targets in OG5_126785
Plasmodium yoelii peroxisomal-coenzyme a synthetase Get druggable targets OG5_126609 All targets in OG5_126609
Brugia malayi glutathione reductase Get druggable targets OG5_126785 All targets in OG5_126785
Plasmodium vivax ATP-dependent Clp protease proteolytic subunit, putative Get druggable targets OG5_127187 All targets in OG5_127187
Mycobacterium ulcerans acyl-CoA synthetase Get druggable targets OG5_126609 All targets in OG5_126609
Theileria parva ATP-dependent Clp protease proteolytic subunit, putative Get druggable targets OG5_127187 All targets in OG5_127187
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_126609 All targets in OG5_126609
Mycobacterium ulcerans ATP-dependent Clp protease proteolytic subunit Get druggable targets OG5_127187 All targets in OG5_127187
Leishmania major 4-coumarate:coa ligase-like protein Get druggable targets OG5_126609 All targets in OG5_126609
Loa Loa (eye worm) MH2 domain-containing protein Get druggable targets OG5_131716 All targets in OG5_131716
Neospora caninum ATP-dependent Clp protease proteolytic subunit, related Get druggable targets OG5_127187 All targets in OG5_127187
Neospora caninum Glutathione reductase, related Get druggable targets OG5_126785 All targets in OG5_126785
Onchocerca volvulus Get druggable targets OG5_126609 All targets in OG5_126609
Candida albicans similar to S. cerevisiae GLR1 (YPL091W) glutathione oxidoreductase Get druggable targets OG5_126785 All targets in OG5_126785
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD2 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) Get druggable targets OG5_126609 All targets in OG5_126609
Leishmania infantum 4-coumarate:coa ligase-like protein Get druggable targets OG5_126609 All targets in OG5_126609
Plasmodium knowlesi glutathione reductase, putative Get druggable targets OG5_126785 All targets in OG5_126785
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD2 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) Get druggable targets OG5_126609 All targets in OG5_126609
Loa Loa (eye worm) glutathione reductase Get druggable targets OG5_126785 All targets in OG5_126785
Plasmodium yoelii ATP-dependent Clp protease, proteolytic subunit ClpP, putative Get druggable targets OG5_127187 All targets in OG5_127187
Toxoplasma gondii thioredoxin reductase Get druggable targets OG5_126785 All targets in OG5_126785
Mycobacterium leprae PROBABLE ATP-DEPENDENT CLP PROTEASE PROTEOLYTIC SUBUNIT 1 CLPP1 (ENDOPEPTIDASE CLP) Get druggable targets OG5_127187 All targets in OG5_127187
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_126609 All targets in OG5_126609
Candida albicans similar to S. cerevisiae GLR1 (YPL091W) glutathione oxidoreductase Get druggable targets OG5_126785 All targets in OG5_126785
Mycobacterium ulcerans fatty-acid-CoA ligase Get druggable targets OG5_126609 All targets in OG5_126609
Leishmania donovani 4-coumarate:coa ligase-like protein Get druggable targets OG5_126609 All targets in OG5_126609
Leishmania donovani trypanothione reductase Get druggable targets OG5_126785 All targets in OG5_126785
Plasmodium knowlesi acyl-CoA synthetase, putative Get druggable targets OG5_126609 All targets in OG5_126609
Brugia malayi Thioredoxin reductase Get druggable targets OG5_126785 All targets in OG5_126785
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD5 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) Get druggable targets OG5_126609 All targets in OG5_126609
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_126609 All targets in OG5_126609
Brugia malayi Probable ClpP-like protease Get druggable targets OG5_127187 All targets in OG5_127187
Schistosoma mansoni peptidase Clp (S14 family) Get druggable targets OG5_127187 All targets in OG5_127187
Leishmania donovani 4-coumarate:coa ligase-like protein Get druggable targets OG5_126609 All targets in OG5_126609
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_127187 All targets in OG5_127187
Plasmodium vivax acyl-CoA synthetase, putative Get druggable targets OG5_126609 All targets in OG5_126609
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_126609 All targets in OG5_126609
Neospora caninum MGC84926 protein, related Get druggable targets OG5_126785 All targets in OG5_126785
Chlamydia trachomatis acylglycerophosphoethanolamine acyltransferase Get druggable targets OG5_126609 All targets in OG5_126609
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_126609 All targets in OG5_126609
Leishmania infantum trypanothione reductase Get druggable targets OG5_126785 All targets in OG5_126785
Brugia malayi AMP-binding enzyme family protein Get druggable targets OG5_126609 All targets in OG5_126609
Plasmodium berghei thioredoxin reductase, putative Get druggable targets OG5_126785 All targets in OG5_126785
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD7 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) Get druggable targets OG5_126609 All targets in OG5_126609
Leishmania major 4-coumarate:coa ligase-like protein Get druggable targets OG5_126609 All targets in OG5_126609
Mycobacterium ulcerans fatty-acid-CoA ligase Get druggable targets OG5_126609 All targets in OG5_126609
Toxoplasma gondii ATP-dependent Clp endopeptidase, proteolytic subunit ClpP domain-containing protein Get druggable targets OG5_127187 All targets in OG5_127187
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD35 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) Get druggable targets OG5_126609 All targets in OG5_126609
Brugia malayi MH2 domain containing protein Get druggable targets OG5_131716 All targets in OG5_131716
Plasmodium yoelii glutathione reductase Get druggable targets OG5_126785 All targets in OG5_126785
Plasmodium berghei acyl-CoA synthetase, putative Get druggable targets OG5_126609 All targets in OG5_126609
Echinococcus multilocularis thioredoxin glutathione reductase Get druggable targets OG5_126785 All targets in OG5_126785
Plasmodium vivax glutathione reductase, putative Get druggable targets OG5_126785 All targets in OG5_126785
Brugia malayi AMP-binding enzyme family protein Get druggable targets OG5_126609 All targets in OG5_126609
Leishmania braziliensis 4-coumarate:coa ligase-like protein Get druggable targets OG5_126609 All targets in OG5_126609
Mycobacterium ulcerans ATP-dependent Clp protease proteolytic subunit Get druggable targets OG5_127187 All targets in OG5_127187
Babesia bovis ATP-dependent Clp protease proteolytic subunit 1, putative Get druggable targets OG5_127187 All targets in OG5_127187
Mycobacterium ulcerans hypothetical protein Get druggable targets OG5_126609 All targets in OG5_126609
Mycobacterium ulcerans long-chain-fatty-acid--CoA ligase Get druggable targets OG5_126609 All targets in OG5_126609
Trypanosoma congolense trypanothione reductase, putative Get druggable targets OG5_126785 All targets in OG5_126785
Plasmodium falciparum ATP-dependent Clp protease proteolytic subunit Get druggable targets OG5_127187 All targets in OG5_127187
Leishmania infantum 4-coumarate:coa ligase-like protein Get druggable targets OG5_126609 All targets in OG5_126609
Plasmodium yoelii thioredoxin reductase Get druggable targets OG5_126785 All targets in OG5_126785
Wolbachia endosymbiont of Brugia malayi ATP-dependent Clp protease proteolytic subunit Get druggable targets OG5_127187 All targets in OG5_127187
Mycobacterium ulcerans long-chain-fatty-acid-CoA ligase Get druggable targets OG5_126609 All targets in OG5_126609
Entamoeba histolytica acyl-CoA synthetase, putative Get druggable targets OG5_126609 All targets in OG5_126609
Mycobacterium leprae PROBABLE ATP-DEPENDENT CLP PROTEASE PROTEOLYTIC SUBUNIT 2 CLPP2 (ENDOPEPTIDASE CLP 2) Get druggable targets OG5_127187 All targets in OG5_127187
Mycobacterium ulcerans long-chain fatty-acid CoA ligase Get druggable targets OG5_126609 All targets in OG5_126609
Plasmodium berghei glutathione reductase, putative Get druggable targets OG5_126785 All targets in OG5_126785
Schistosoma japonicum ko:K00384 thioredoxin reductase (NADPH) [EC1.8.1.9], putative Get druggable targets OG5_126785 All targets in OG5_126785
Mycobacterium ulcerans acyl-CoA synthetase Get druggable targets OG5_126609 All targets in OG5_126609
Mycobacterium tuberculosis NADPH-dependent mycothiol reductase Mtr Get druggable targets OG5_126785 All targets in OG5_126785
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_126609 All targets in OG5_126609
Leishmania mexicana 4-coumarate:coa ligase-like protein Get druggable targets OG5_126609 All targets in OG5_126609
Leishmania infantum 4-coumarate:coa ligase-like protein Get druggable targets OG5_126609 All targets in OG5_126609
Trypanosoma brucei gambiense trypanothione reductase, putative Get druggable targets OG5_126785 All targets in OG5_126785
Entamoeba histolytica acyl-coA synthetase, putative Get druggable targets OG5_126609 All targets in OG5_126609
Entamoeba histolytica acyl-CoA synthetase, putative Get druggable targets OG5_126609 All targets in OG5_126609
Plasmodium vivax thioredoxin reductase, putative Get druggable targets OG5_126785 All targets in OG5_126785
Cryptosporidium hominis thioredoxin reductase Get druggable targets OG5_126785 All targets in OG5_126785
Chlamydia trachomatis ATP-dependent Clp protease proteolytic subunit Get druggable targets OG5_127187 All targets in OG5_127187
Leishmania major trypanothione reductase Get druggable targets OG5_126785 All targets in OG5_126785
Loa Loa (eye worm) thioredoxin reductase Get druggable targets OG5_126785 All targets in OG5_126785
Leishmania infantum 4-coumarate:coa ligase-like protein Get druggable targets OG5_126609 All targets in OG5_126609
Mycobacterium ulcerans acyl-CoA synthetase Get druggable targets OG5_126609 All targets in OG5_126609
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_126609 All targets in OG5_126609
Schistosoma japonicum ko:K06275 parvin, putative Get druggable targets OG5_127187 All targets in OG5_127187
Leishmania mexicana 4-coumarate:coa ligase-like protein Get druggable targets OG5_126609 All targets in OG5_126609
Cryptosporidium parvum thioredoxin reductase 1 Get druggable targets OG5_126785 All targets in OG5_126785
Chlamydia trachomatis ATP-dependent Clp protease proteolytic subunit Get druggable targets OG5_127187 All targets in OG5_127187
Babesia bovis thiodoxin reductase, putative Get druggable targets OG5_126785 All targets in OG5_126785
Brugia malayi AMP-binding enzyme family protein Get druggable targets OG5_126609 All targets in OG5_126609
Plasmodium berghei ATP-dependent Clp protease proteolytic subunit, putative Get druggable targets OG5_127187 All targets in OG5_127187
Mycobacterium tuberculosis Probable chain -fatty-acid-CoA ligase FadD13 (fatty-acyl-CoA synthetase) Get druggable targets OG5_126609 All targets in OG5_126609

By sequence similarity to non orthologous known druggable targets
Species Potential target Known druggable target Length Alignment span Identity
Cryptosporidium parvum putative long chain fatty acyl CoA synthetase having a signal peptide Luciferin 4-monooxygenase   550 aa 472 aa 24.8 %
Leishmania braziliensis acetyl-CoA synthetase, putative Luciferin 4-monooxygenase   550 aa 596 aa 21.1 %
Dictyostelium discoideum hypothetical protein Luciferin 4-monooxygenase   550 aa 542 aa 22.1 %
Echinococcus multilocularis long chain fatty acid coenzyme A ligase 1 Luciferin 4-monooxygenase   550 aa 443 aa 26.4 %
Trichomonas vaginalis long-chain-fatty-acid CoA ligase, putative Luciferin 4-monooxygenase   550 aa 466 aa 21.7 %
Trichomonas vaginalis AMP dependent ligase, putative Luciferin 4-monooxygenase   550 aa 445 aa 26.1 %
Mycobacterium leprae Probable fatty-acid-CoA synthetase FadD28 (fatty-acid-CoA ligase) (fatty-acid-CoA synthase) Luciferin 4-monooxygenase   550 aa 484 aa 20.5 %
Dictyostelium discoideum AMP-dependent synthetase and ligase domain-containing protein Luciferin 4-monooxygenase   550 aa 550 aa 20.9 %
Babesia bovis ATP-dependent Clp protease proteolytic subunit, putative ATP-dependent Clp protease proteolytic subunit   197 aa 188 aa 41.5 %
Cryptosporidium hominis acetyl-CoenzymeA synthetase (acetate--coa ligase) (acyl-activating enzyme) Luciferin 4-monooxygenase   550 aa 549 aa 22.6 %
Dictyostelium discoideum hypothetical protein Luciferin 4-monooxygenase   550 aa 535 aa 21.7 %
Dictyostelium discoideum hypothetical protein Luciferin 4-monooxygenase   550 aa 541 aa 21.4 %
Trichomonas vaginalis AMP dependent ligase/synthetase, putative Luciferin 4-monooxygenase   550 aa 554 aa 22.9 %
Mycobacterium leprae Probable fatty-acid-CoA synthetase FadD32 (fatty-acid-CoA ligase) (fatty-acid-CoA synthase) Luciferin 4-monooxygenase   550 aa 442 aa 23.5 %
Leishmania braziliensis long chain fatty Acyl CoA synthetase, putative Luciferin 4-monooxygenase   550 aa 496 aa 22.8 %
Neospora caninum Dihydrolipoyl dehydrogenase (EC 1.8.1.4), related Thioredoxin glutathione reductase   598 aa 512 aa 28.3 %
Dictyostelium discoideum AMP-dependent synthetase and ligase domain-containing protein Luciferin 4-monooxygenase   550 aa 545 aa 24.9 %
Mycobacterium tuberculosis Fatty-acid-AMP ligase FadD32 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase). Also shown to have acyl-ACP ligase activity. Luciferin 4-monooxygenase   550 aa 487 aa 22.4 %
Plasmodium vivax ATP-dependent Clp protease proteolytic subunit, putative ATP-dependent Clp protease proteolytic subunit   197 aa 189 aa 35.5 %
Mycobacterium tuberculosis Bifunctional enzyme MbtA: salicyl-AMP ligase (SAL-AMP ligase) + salicyl-S-ArCP synthetase Luciferin 4-monooxygenase   550 aa 536 aa 24.4 %
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD8 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) Luciferin 4-monooxygenase   550 aa 505 aa 28.1 %
Entamoeba histolytica acyl-CoA synthetase, putative Luciferin 4-monooxygenase   550 aa 446 aa 22.0 %
Neospora caninum acetyl-coenzyme a synthetase, putative Luciferin 4-monooxygenase   550 aa 549 aa 20.9 %
Onchocerca volvulus Luciferin 4-monooxygenase   550 aa 502 aa 24.9 %
Mycobacterium leprae ATP-dependent Clp protease proteolytic subunit 1 ATP-dependent Clp protease proteolytic subunit   197 aa 172 aa 57.0 %
Candida albicans similar to S. cerevisiae FAT1 (YBR041W) fatty acid transporter and very long-chain fatty acyl-CoA synthetase Luciferin 4-monooxygenase   550 aa 496 aa 24.2 %
Schistosoma japonicum ko:K08745 solute carrier family 27 (fatty acid transporter), member 1, putative Luciferin 4-monooxygenase   550 aa 501 aa 24.6 %
Dictyostelium discoideum hypothetical protein Luciferin 4-monooxygenase   550 aa 522 aa 19.9 %
Mycobacterium ulcerans acyl-CoA synthetase Luciferin 4-monooxygenase   550 aa 593 aa 22.1 %
Dictyostelium discoideum hypothetical protein Luciferin 4-monooxygenase   550 aa 542 aa 18.3 %
Mycobacterium ulcerans long-chain-fatty-acid-CoA ligase, FadD11 Luciferin 4-monooxygenase   550 aa 492 aa 24.6 %
Schistosoma japonicum ko:K01897 long-chain fatty-acid-CoA ligase [EC6.2.1.3], putative Luciferin 4-monooxygenase   550 aa 466 aa 27.3 %
Dictyostelium discoideum hypothetical protein Luciferin 4-monooxygenase   550 aa 522 aa 19.9 %
Leishmania infantum long chain fatty Acyl CoA synthetase, putative Luciferin 4-monooxygenase   550 aa 500 aa 23.4 %
Dictyostelium discoideum hypothetical protein Luciferin 4-monooxygenase   550 aa 541 aa 21.6 %
Mycobacterium ulcerans non-ribosomal peptide synthetase MbtF Luciferin 4-monooxygenase   550 aa 558 aa 20.1 %
Mycobacterium leprae Probable fatty-acid-CoA ligase FadD9 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) Luciferin 4-monooxygenase   550 aa 461 aa 22.3 %
Mycobacterium tuberculosis Probable fatty-acid-AMP ligase FadD25 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) Luciferin 4-monooxygenase   550 aa 475 aa 21.1 %
Mycobacterium ulcerans non-ribosomal peptide synthetase Luciferin 4-monooxygenase   550 aa 541 aa 22.4 %
Leishmania mexicana long chain fatty Acyl CoA synthetase, putative Luciferin 4-monooxygenase   550 aa 483 aa 23.8 %
Brugia malayi AMP-binding enzyme family protein Luciferin 4-monooxygenase   550 aa 544 aa 21.5 %
Brugia malayi MH2 domain containing protein SMAD family member 2 467 aa 405 aa 31.6 %
Trypanosoma cruzi fatty acyl CoA synthetase, putative Luciferin 4-monooxygenase   550 aa 482 aa 24.7 %
Dictyostelium discoideum hypothetical protein Luciferin 4-monooxygenase   550 aa 576 aa 19.8 %
Trypanosoma brucei fatty acyl CoA synthetase 3 Luciferin 4-monooxygenase   550 aa 491 aa 23.6 %
Onchocerca volvulus Putative V-type proton ATPase subunit F ATP-dependent Clp protease proteolytic subunit   197 aa 194 aa 54.1 %
Dictyostelium discoideum fatty acyl-CoA synthetase Luciferin 4-monooxygenase   550 aa 501 aa 24.4 %
Onchocerca volvulus Lysine-specific histone demethylase 1A homolog Luciferin 4-monooxygenase   550 aa 550 aa 22.5 %
Dictyostelium discoideum hypothetical protein Luciferin 4-monooxygenase   550 aa 538 aa 21.8 %
Dictyostelium discoideum hypothetical protein Luciferin 4-monooxygenase   550 aa 507 aa 20.9 %
Dictyostelium discoideum hypothetical protein Luciferin 4-monooxygenase   550 aa 499 aa 19.2 %
Candida albicans similar to S. cerevisiae ACS2 (YLR153C) acetyl-CoA synthetase Luciferin 4-monooxygenase   550 aa 543 aa 24.5 %
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD34 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) Luciferin 4-monooxygenase   550 aa 537 aa 20.9 %
Dictyostelium discoideum hypothetical protein Luciferin 4-monooxygenase   550 aa 535 aa 22.6 %
Mycobacterium ulcerans fatty-acid-CoA ligase FadD11 Luciferin 4-monooxygenase   550 aa 498 aa 23.5 %
Mycobacterium tuberculosis Probable fatty-acid-AMP ligase FadD24 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) Luciferin 4-monooxygenase   550 aa 526 aa 21.9 %
Echinococcus granulosus long chain fatty acid coenzyme A ligase 5 Luciferin 4-monooxygenase   550 aa 458 aa 25.8 %
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein Luciferin 4-monooxygenase   550 aa 476 aa 22.5 %
Plasmodium yoelii Clp protease ATP-dependent Clp protease proteolytic subunit   197 aa 183 aa 36.6 %
Trichomonas vaginalis AMP dependent ligase/synthetase, putative Luciferin 4-monooxygenase   550 aa 494 aa 24.3 %
Trypanosoma brucei gambiense fatty acyl CoA synthetase 3 Luciferin 4-monooxygenase   550 aa 491 aa 23.6 %
Plasmodium falciparum dihydrolipoyl dehydrogenase, apicoplast Thioredoxin glutathione reductase   598 aa 513 aa 25.0 %
Entamoeba histolytica long-chain-fatty-acid--CoA ligase, putative Luciferin 4-monooxygenase   550 aa 480 aa 21.5 %
Dictyostelium discoideum hypothetical protein Luciferin 4-monooxygenase   550 aa 541 aa 21.6 %
Dictyostelium discoideum hypothetical protein Luciferin 4-monooxygenase   550 aa 542 aa 22.1 %
Cryptosporidium parvum acetyl-coenzyme A synthetase Luciferin 4-monooxygenase   550 aa 545 aa 22.8 %
Neospora caninum hypothetical protein Thioredoxin glutathione reductase   598 aa 485 aa 30.5 %
Trichomonas vaginalis AMP dependent ligase/synthetase, putative Luciferin 4-monooxygenase   550 aa 554 aa 24.4 %
Dictyostelium discoideum AMP-dependent synthetase and ligase domain-containing protein Luciferin 4-monooxygenase   550 aa 531 aa 19.0 %
Dictyostelium discoideum acetyl-CoA ligase Luciferin 4-monooxygenase   550 aa 549 aa 22.2 %
Leishmania braziliensis acetyl-CoA synthetase, putative Luciferin 4-monooxygenase   550 aa 603 aa 22.6 %
Mycobacterium ulcerans non-ribosomal peptide synthetase MbtE Luciferin 4-monooxygenase   550 aa 502 aa 22.5 %
Plasmodium knowlesi ATP-dependent Clp protease proteolytic subunit, putative ATP-dependent Clp protease proteolytic subunit   197 aa 189 aa 36.0 %
Trichomonas vaginalis AMP dependent ligase/synthetase, putative Luciferin 4-monooxygenase   550 aa 526 aa 22.4 %
Mycobacterium tuberculosis Fatty-acid-AMP ligase FadD28 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) Luciferin 4-monooxygenase   550 aa 504 aa 22.6 %
Echinococcus multilocularis long chain fatty acid transport protein 4 Luciferin 4-monooxygenase   550 aa 476 aa 22.3 %
Echinococcus multilocularis long chain fatty acid coenzyme A ligase 5 Luciferin 4-monooxygenase   550 aa 458 aa 25.5 %
Loa Loa (eye worm) AMP-binding enzyme family protein Luciferin 4-monooxygenase   550 aa 489 aa 23.3 %
Mycobacterium leprae FATTY-ACID-CoA LIGASE FADD26 (FATTY-ACID-COA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) Luciferin 4-monooxygenase   550 aa 533 aa 22.7 %
Plasmodium knowlesi dihydrolipoyl dehydrogenase, apicoplast, putative Thioredoxin glutathione reductase   598 aa 518 aa 22.0 %
Trichomonas vaginalis AMP dependent ligase/synthetase, putative Luciferin 4-monooxygenase   550 aa 476 aa 23.5 %
Mycobacterium ulcerans peptide synthetase Nrp (peptide synthase) Luciferin 4-monooxygenase   550 aa 535 aa 23.2 %
Schistosoma mansoni neuropeptide receptor ATP-dependent Clp protease proteolytic subunit   197 aa 174 aa 20.1 %
Mycobacterium tuberculosis Probable fatty-acid-AMP ligase FadD21 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) Luciferin 4-monooxygenase   550 aa 586 aa 24.4 %
Brugia malayi AMP-binding enzyme family protein Luciferin 4-monooxygenase   550 aa 497 aa 24.7 %
Mycobacterium ulcerans acyl-CoA synthetase Luciferin 4-monooxygenase   550 aa 497 aa 19.3 %
Mycobacterium tuberculosis P-hydroxybenzoyl-AMP ligase FadD22 Luciferin 4-monooxygenase   550 aa 493 aa 22.1 %
Mycobacterium ulcerans long-chain-fatty-acid-CoA ligase FadD15 Luciferin 4-monooxygenase   550 aa 482 aa 24.3 %
Mycobacterium tuberculosis Fatty-acid-AMP ligase FadD26 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) Luciferin 4-monooxygenase   550 aa 560 aa 21.4 %
Mycobacterium leprae Probable fatty-acid-CoA synthetase FadD22 (fatty-acid-CoA ligase) (fatty-acid-CoA synthase) Luciferin 4-monooxygenase   550 aa 493 aa 20.7 %
Plasmodium berghei dihydrolipoyl dehydrogenase, apicoplast, putative Thioredoxin glutathione reductase   598 aa 538 aa 25.3 %
Leishmania major long chain fatty Acyl CoA synthetase, putative Luciferin 4-monooxygenase   550 aa 482 aa 23.2 %
Mycobacterium ulcerans acyl-CoA synthetase Luciferin 4-monooxygenase   550 aa 530 aa 23.8 %
Schistosoma japonicum ko:K01897 long-chain fatty-acid-CoA ligase [EC6.2.1.3], putative Luciferin 4-monooxygenase   550 aa 541 aa 22.4 %
Entamoeba histolytica long-chain-fatty-acid--CoA ligase, putative Luciferin 4-monooxygenase   550 aa 476 aa 20.8 %
Neospora caninum Short-chain dehydrogenase/reductase SDR, related Luciferin 4-monooxygenase   550 aa 518 aa 19.1 %
Leishmania mexicana acetyl-CoA synthetase, putative Luciferin 4-monooxygenase   550 aa 559 aa 20.6 %
Dictyostelium discoideum hypothetical protein Luciferin 4-monooxygenase   550 aa 539 aa 19.1 %
Treponema pallidum ATP-dependent Clp protease proteolytic subunit ATP-dependent Clp protease proteolytic subunit   197 aa 186 aa 40.3 %
Toxoplasma gondii type I fatty acid synthase, putative Luciferin 4-monooxygenase   550 aa 514 aa 19.8 %
Plasmodium falciparum ATP-dependent Clp protease proteolytic subunit ATP-dependent Clp protease proteolytic subunit   197 aa 183 aa 36.1 %
Trichomonas vaginalis AMP dependent CoA ligase, putative Luciferin 4-monooxygenase   550 aa 492 aa 23.6 %
Chlamydia trachomatis hypothetical protein ATP-dependent Clp protease proteolytic subunit   197 aa 171 aa 22.8 %
Candida albicans similar to S. cerevisiae FAT1 (YBR041W) fatty acid transporter and very long-chain fatty acyl-CoA synthetase Luciferin 4-monooxygenase   550 aa 496 aa 24.2 %
Mycobacterium ulcerans putative fatty-acid--CoA ligase Luciferin 4-monooxygenase   550 aa 576 aa 20.8 %
Trichomonas vaginalis AMP dependent CoA ligase, putative Luciferin 4-monooxygenase   550 aa 527 aa 25.0 %
Onchocerca volvulus Matrilysin homolog Luciferin 4-monooxygenase   550 aa 466 aa 24.2 %
Dictyostelium discoideum hypothetical protein Luciferin 4-monooxygenase   550 aa 538 aa 21.8 %
Dictyostelium discoideum hypothetical protein Luciferin 4-monooxygenase   550 aa 558 aa 20.4 %
Trypanosoma brucei gambiense fatty acyl CoA synthetase 4, putative Luciferin 4-monooxygenase   550 aa 497 aa 23.7 %
Mycobacterium tuberculosis Probable fatty-acid-AMP ligase FadD23 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) Luciferin 4-monooxygenase   550 aa 542 aa 23.8 %
Cryptosporidium parvum acyl-CoA synthetase Luciferin 4-monooxygenase   550 aa 460 aa 25.7 %
Echinococcus granulosus long chain fatty acid transport protein 4 Luciferin 4-monooxygenase   550 aa 476 aa 22.3 %
Mycobacterium ulcerans acyl-CoA synthetase Luciferin 4-monooxygenase   550 aa 582 aa 22.3 %
Trichomonas vaginalis long-chain-fatty-acid CoA ligase, putative Luciferin 4-monooxygenase   550 aa 490 aa 23.3 %
Trichomonas vaginalis AMP dependent CoA ligase, putative Luciferin 4-monooxygenase   550 aa 524 aa 24.0 %
Leishmania donovani long chain fatty Acyl CoA synthetase, putative Luciferin 4-monooxygenase   550 aa 500 aa 23.4 %
Mycobacterium tuberculosis Probable acyl-CoA ligase FadD31 (acyl-CoA synthetase) (acyl-CoA synthase) Luciferin 4-monooxygenase   550 aa 592 aa 20.4 %
Trypanosoma cruzi fatty acyl CoA synthetase, putative Luciferin 4-monooxygenase   550 aa 480 aa 25.2 %
Plasmodium yoelii dihydrolipoamide dehydrogenase Thioredoxin glutathione reductase   598 aa 537 aa 24.2 %
Toxoplasma gondii propionate-CoA ligase Luciferin 4-monooxygenase   550 aa 550 aa 21.1 %
Mycobacterium tuberculosis Probable peptide synthetase Nrp (peptide synthase) Luciferin 4-monooxygenase   550 aa 509 aa 22.6 %
Dictyostelium discoideum hypothetical protein Luciferin 4-monooxygenase   550 aa 478 aa 21.1 %
Echinococcus granulosus long chain fatty acid coenzyme A ligase 1 Luciferin 4-monooxygenase   550 aa 452 aa 26.1 %
Mycobacterium ulcerans acyl-CoA synthetase Luciferin 4-monooxygenase   550 aa 601 aa 22.5 %
Theileria parva long-chain fatty acid CoA ligase, putative Luciferin 4-monooxygenase   550 aa 507 aa 23.5 %
Dictyostelium discoideum hypothetical protein Luciferin 4-monooxygenase   550 aa 463 aa 23.5 %
Plasmodium berghei ATP-dependent Clp protease proteolytic subunit, putative ATP-dependent Clp protease proteolytic subunit   197 aa 180 aa 36.7 %
Mycobacterium leprae Probable fatty-acid-CoA synthetase FadD29 (fatty-acid-CoA ligase) (fatty-acid-CoA synthase) Luciferin 4-monooxygenase   550 aa 529 aa 22.3 %
Onchocerca volvulus Luciferin 4-monooxygenase   550 aa 487 aa 23.8 %
Candida albicans similar to S. cerevisiae FAA4 (YMR246W) long-chain fatty acid--CoA synthetase Luciferin 4-monooxygenase   550 aa 478 aa 23.4 %
Babesia bovis fatty acyl-CoA synthetase family protein Luciferin 4-monooxygenase   550 aa 461 aa 23.4 %
Plasmodium vivax dihydrolipoyl dehydrogenase, apicoplast, putative Thioredoxin glutathione reductase   598 aa 521 aa 21.5 %
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD9 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) Luciferin 4-monooxygenase   550 aa 480 aa 22.5 %
Babesia bovis ATP-dependent Clp protease proteolytic subunit, putative ATP-dependent Clp protease proteolytic subunit   197 aa 188 aa 41.5 %
Trichomonas vaginalis antibiotic synthetase, putative Luciferin 4-monooxygenase   550 aa 581 aa 21.2 %
Dictyostelium discoideum hypothetical protein Luciferin 4-monooxygenase   550 aa 542 aa 18.3 %
Echinococcus multilocularis long chain fatty acid coenzyme A ligase 1 Luciferin 4-monooxygenase   550 aa 459 aa 27.0 %
Candida albicans similar to S. cerevisiae ACS2 (YLR153C) acetyl-CoA synthetase Luciferin 4-monooxygenase   550 aa 539 aa 22.1 %
Neospora caninum glutathione reductase, putative Thioredoxin glutathione reductase   598 aa 532 aa 34.6 %
Mycobacterium tuberculosis Fatty-acid-AMP ligase FadD29 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) Luciferin 4-monooxygenase   550 aa 617 aa 22.2 %
Mycobacterium ulcerans long-chain-fatty-acid--CoA ligase Luciferin 4-monooxygenase   550 aa 509 aa 21.8 %
Cryptosporidium hominis acyl-CoA synthetase Luciferin 4-monooxygenase   550 aa 460 aa 26.1 %
Trichomonas vaginalis antibiotic synthetase, putative Luciferin 4-monooxygenase   550 aa 577 aa 22.2 %
Candida albicans similar to S. cerevisiae ACS2 (YLR153C) acetyl-CoA synthetase Luciferin 4-monooxygenase   550 aa 543 aa 24.5 %
Trypanosoma congolense fatty acyl CoA synthetase 2, putative Luciferin 4-monooxygenase   550 aa 500 aa 22.4 %
Mycobacterium ulcerans long-chain-fatty-acid-CoA ligase FadD15 Luciferin 4-monooxygenase   550 aa 484 aa 26.0 %
Dictyostelium discoideum AMP-dependent synthetase and ligase domain-containing protein Luciferin 4-monooxygenase   550 aa 517 aa 24.8 %
Babesia bovis long-chain acyl-CoA synthetase, putative Luciferin 4-monooxygenase   550 aa 445 aa 21.8 %
Toxoplasma gondii NADPH-glutathione reductase Thioredoxin glutathione reductase   598 aa 555 aa 33.5 %
Onchocerca volvulus Thioredoxin glutathione reductase   598 aa 533 aa 50.8 %
Trypanosoma cruzi fatty acyl CoA synthetase 2, putative Luciferin 4-monooxygenase   550 aa 495 aa 22.6 %
Candida albicans similar to S. cerevisiae ACS2 (YLR153C) acetyl-CoA synthetase Luciferin 4-monooxygenase   550 aa 539 aa 22.1 %
Mycobacterium leprae PROBABLE FATTY-ACID--CoA LIGASE FADD21 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) Luciferin 4-monooxygenase   550 aa 565 aa 22.8 %
Dictyostelium discoideum hypothetical protein Luciferin 4-monooxygenase   550 aa 539 aa 19.1 %
Dictyostelium discoideum fatty acyl-CoA synthetase Luciferin 4-monooxygenase   550 aa 462 aa 23.8 %
Mycobacterium leprae Probable long-chain-fatty-acid-CoA ligase FadD15 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) Luciferin 4-monooxygenase   550 aa 484 aa 23.3 %
Dictyostelium discoideum hypothetical protein Luciferin 4-monooxygenase   550 aa 541 aa 21.4 %
Entamoeba histolytica long-chain-fatty-acid--CoA ligase, putative Luciferin 4-monooxygenase   550 aa 494 aa 23.9 %
Schistosoma mansoni FAA1 Long-chain-fatty-acid--CoA ligase 1 Luciferin 4-monooxygenase   550 aa 494 aa 26.3 %
Leishmania braziliensis long-chain-fatty-acid-CoA ligase, putative Luciferin 4-monooxygenase   550 aa 504 aa 25.6 %
Mycobacterium ulcerans fatty-acid-CoA ligase FadD9 Luciferin 4-monooxygenase   550 aa 463 aa 21.8 %

Obtained from network model

Ranking Plot


Putative Targets List


Species Potential target Raw Global Species
Plasmodium vivax multidomain scavenger receptor, putative 0.0161 0.051 0.6587
Brugia malayi beta-lactamase family protein 0.0071 0.0185 0.0282
Brugia malayi Tyrosyl-DNA phosphodiesterase family protein 0.007 0.0179 0.0273
Trypanosoma cruzi hypothetical protein, conserved 0.0071 0.0185 0.2232
Echinococcus granulosus Nuclear hormone receptor HR96 0.006 0.0142 0.0133
Echinococcus multilocularis expressed protein 0.0026 0.0021 0.0005
Loa Loa (eye worm) hypothetical protein 0.0172 0.0548 0.099
Echinococcus multilocularis mitogen activated protein kinase 0.0157 0.0495 0.048
Mycobacterium leprae PROBABLE ATP-DEPENDENT CLP PROTEASE PROTEOLYTIC SUBUNIT 1 CLPP1 (ENDOPEPTIDASE CLP) 0.0062 0.0151 0.0277
Schistosoma mansoni bcl-2 homologous antagonist/killer (bak) 0.0087 0.0241 0.0237
Schistosoma mansoni aldehyde dehydrogenase 0.0123 0.0373 0.0369
Mycobacterium tuberculosis Probable oxidoreductase 0.0116 0.0345 0.0709
Toxoplasma gondii glycosyl hydrolase, family 31 protein 0.0044 0.0085 0.0202
Schistosoma mansoni hypothetical protein 0.0094 0.0267 0.0264
Echinococcus multilocularis caspase 3 0.0074 0.0194 0.0178
Toxoplasma gondii ICE family protease (caspase) p20 domain-containing protein 0.0027 0.0024 0.0024
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 8 0.0121 0.0365 0.035
Trichomonas vaginalis sucrase-isomaltase, putative 0.0044 0.0085 0.0725
Echinococcus granulosus thyroid hormone receptor alpha 0.006 0.0142 0.0133
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD2 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0029 0.003 0.0029
Loa Loa (eye worm) hypothetical protein 0.0155 0.0485 0.0876
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0126 0.0383 0.0601
Wolbachia endosymbiont of Brugia malayi 3-oxoacyl-ACP synthase 0.0234 0.0772 1
Toxoplasma gondii quinone oxidoreductase, putative 0.0058 0.0136 0.0353
Echinococcus granulosus L aminoadipate semialdehyde 0.0088 0.0244 0.0235
Schistosoma mansoni coup transcription factor 0.0126 0.0383 0.0379
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0034 0.005 0.0393
Echinococcus granulosus Malonyl coenzyme A acyl carrier protein transacylase 0.0059 0.014 0.013
Mycobacterium ulcerans quinone oxidoreductase 0.0058 0.0136 0.0271
Mycobacterium ulcerans polyketide synthase MbtC 0.0234 0.0772 0.1579
Trichomonas vaginalis penicillin-binding protein, putative 0.0071 0.0185 0.1691
Loa Loa (eye worm) hypothetical protein 0.0033 0.0045 0.0074
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0034 0.005 0.0393
Onchocerca volvulus 0.0226 0.0745 0.1228
Echinococcus granulosus caspase 3 apoptosis cysteine peptidase 0.0101 0.0291 0.0282
Echinococcus granulosus tumor protein p63 0.1733 0.6187 0.6183
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.0126 0.0383 0.0367
Mycobacterium tuberculosis Phenolpthiocerol synthesis type-I polyketide synthase PpsC 0.0907 0.3203 0.6578
Mycobacterium tuberculosis Polyketide synthetase MbtD (polyketide synthase) 0.0287 0.0963 0.1977
Leishmania major heat shock protein 83-1 0.0068 0.0173 0.1699
Plasmodium vivax basic transcription factor 3b, putative 0.0036 0.0056 0.0674
Mycobacterium tuberculosis Probable polyketide synthase Pks9 0.053 0.1842 0.3783
Leishmania major cytochrome p450-like protein 0.0038 0.0063 0.0506
Trypanosoma brucei PAB1-binding protein , putative 0.0077 0.0206 0.2509
Onchocerca volvulus 0.0034 0.005 0.0068
Echinococcus granulosus heat shock protein heat shock protein 90 alpha 0.0054 0.0123 0.0114
Echinococcus multilocularis cathepsin l cysteine peptidase 0.0034 0.005 0.0034
Loa Loa (eye worm) endoplasmin 0.0068 0.0173 0.0308
Onchocerca volvulus Peroxidasin homolog 0.0087 0.0242 0.0388
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0126 0.0383 0.0374
Mycobacterium tuberculosis Fatty-acid-AMP ligase FadD30 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) 0.0021 0.0004 0.0009
Plasmodium vivax metacaspase 1, putative 0.0027 0.0024 0.0261
Loa Loa (eye worm) glutaminase 0.031 0.1047 0.1898
Leishmania major hypothetical protein, conserved 0.0071 0.0185 0.1824
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative 0.004 0.0073 0.0749
Brugia malayi ecdysone receptor 0.006 0.0142 0.0213
Echinococcus granulosus ATP dependent Clp protease proteolytic subunit 0.0094 0.0268 0.0259
Echinococcus granulosus caspase 8 0.0027 0.0024 0.0015
Leishmania major 3-oxoacyl-(acyl-carrier protein) reductase, putative 0.0231 0.0761 0.8049
Loa Loa (eye worm) hypothetical protein 0.0126 0.0383 0.0689
Echinococcus multilocularis Ataxin 2, N terminal,domain containing protein 0.0035 0.0052 0.0036
Onchocerca volvulus Putative organic anion transporter 0.0226 0.0745 0.1228
Onchocerca volvulus Peroxidase homolog 0.0087 0.0241 0.0387
Schistosoma mansoni alcohol dehydrogenase 0.0058 0.0136 0.0133
Loa Loa (eye worm) alcohol dehydrogenase class III 0.0058 0.0136 0.024
Echinococcus multilocularis L aminoadipate semialdehyde 0.0088 0.0244 0.0228
Trichomonas vaginalis glucosylceramidase, putative 0.0093 0.0262 0.2437
Trichomonas vaginalis alpha-glucosidase, putative 0.0044 0.0085 0.0725
Trypanosoma cruzi heat shock protein 90, putative 0.0068 0.0173 0.2079
Echinococcus granulosus snurportin 1 0.0358 0.1219 0.1211
Leishmania major cathepsin L-like protease 0.013 0.0397 0.4112
Mycobacterium tuberculosis Conserved hypothetical protein 0.0094 0.0267 0.0549
Onchocerca volvulus 0.0118 0.0354 0.0575
Entamoeba histolytica myo-inositol monophosphatase, putative 0.0038 0.0064 0.1505
Loa Loa (eye worm) apoptosis regulator protein 0.0087 0.0241 0.0431
Schistosoma mansoni gcn5proteinral control of amino-acid synthesis 5-like 2 gcnl2 0.029 0.0976 0.0973
Trichomonas vaginalis endoplasmin, putative 0.0042 0.0078 0.0661
Mycobacterium leprae PROBABLE CHAPERONE PROTEIN HTPG (HEAT SHOCK PROTEIN) (HSP90 FAMILY PROTEIN) (HIGH TEMPERATURE PROTEIN G) 0.0054 0.0123 0.022
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.0126 0.0383 0.0689
Trypanosoma brucei glucosidase, putative 0.0044 0.0085 0.0907
Leishmania major cathepsin L-like protease 0.0034 0.005 0.0369
Entamoeba histolytica hypothetical protein 0.0037 0.006 0.1392
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0034 0.005 0.0393
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0092 0.026 0.0251
Echinococcus multilocularis cytoplasmic intermediate filament protein 0.0066 0.0165 0.0149
Onchocerca volvulus 0.0126 0.0383 0.0623
Schistosoma mansoni cpg binding protein 0.0029 0.003 0.0026
Trichomonas vaginalis conserved hypothetical protein 0.0036 0.0056 0.0449
Onchocerca volvulus 0.0226 0.0745 0.1228
Trypanosoma brucei transcription factor BTF3, putative 0.0036 0.0056 0.0528
Toxoplasma gondii acyl carrier protein ACP 0.0094 0.0267 0.0739
Brugia malayi beta-NAC-like protein 0.0036 0.0056 0.0075
Schistosoma mansoni lipoxygenase 0.0291 0.0978 0.0975
Echinococcus granulosus cathepsin l cysteine peptidase 0.0034 0.005 0.0041
Loa Loa (eye worm) hypothetical protein 0.0058 0.0136 0.024
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.0071 0.0185 0.038
Echinococcus multilocularis cysteine protease 0.0034 0.005 0.0034
Mycobacterium tuberculosis Polyketide synthase Pks2 0.0904 0.3192 0.6556
Onchocerca volvulus Protein ultraspiracle homolog 0.0126 0.0383 0.0623
Toxoplasma gondii heat shock protein 90, putative 0.0068 0.0173 0.0462
Plasmodium vivax 3-oxoacyl-[acyl-carrier-protein] synthase i/ii, putative 0.0234 0.0772 1
Mycobacterium tuberculosis Probable ATP-dependent CLP protease proteolytic subunit 2 ClpP2 (endopeptidase CLP 2) 0.0062 0.0151 0.0309
Onchocerca volvulus 0.0226 0.0745 0.1228
Trichomonas vaginalis glucosylceramidase, putative 0.0093 0.0262 0.2437
Leishmania major heat shock protein 83-1 0.0068 0.0173 0.1699
Schistosoma mansoni transient receptor potential channel 0.0064 0.0157 0.0154
Trypanosoma cruzi apurinic/apyrimidinic endonuclease 0.004 0.0073 0.0749
Echinococcus granulosus Bcl 2 ous antagonist:killer 0.0087 0.0241 0.0231
Entamoeba histolytica glycosyl hydrolase, family 31 protein 0.0044 0.0085 0.2082
Loa Loa (eye worm) hypothetical protein 0.0067 0.0168 0.0298
Trichomonas vaginalis glucosylceramidase, putative 0.0098 0.028 0.2611
Toxoplasma gondii Hsp90 domain-containing protein 0.0028 0.0028 0.0035
Wolbachia endosymbiont of Brugia malayi fructose-1,6-bisphosphatase 0.0038 0.0064 0.0631
Loa Loa (eye worm) hypothetical protein 0.0058 0.0136 0.024
Giardia lamblia Grp94/Hsp90 0.0054 0.0123 0.1157
Mycobacterium ulcerans thioesterase TesA 0.0777 0.2734 0.5611
Trypanosoma cruzi metacaspase 5, putative 0.0027 0.0024 0.0109
Echinococcus granulosus Nuclear hormone receptor HR96 0.006 0.0142 0.0133
Leishmania major aldehyde dehydrogenase, mitochondrial precursor 0.0123 0.0373 0.3854
Plasmodium falciparum thioredoxin reductase 0.0046 0.0092 0.1142
Mycobacterium tuberculosis Bacterioferritin BfrB 0.0026 0.0021 0.0042
Brugia malayi intermediate filament protein 0.0136 0.042 0.0661
Leishmania major apurinic/apyrimidinic endonuclease-redox protein 0.004 0.0073 0.0612
Schistosoma mansoni hypothetical protein 0.0141 0.0438 0.0435
Loa Loa (eye worm) hypothetical protein 0.0029 0.003 0.0048
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0092 0.026 0.0251
Schistosoma mansoni cathepsin F (C01 family) 0.0034 0.005 0.0047
Mycobacterium ulcerans NADP-dependent alcohol dehydrogenase Adh 0.0058 0.0136 0.0271
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0126 0.0383 0.0601
Mycobacterium tuberculosis Probable polyketide synthase Pks8 0.0737 0.2589 0.5318
Trypanosoma brucei metacaspase 0.0027 0.0024 0.0109
Entamoeba histolytica transcription factor BTF3, putative 0.0036 0.0056 0.1288
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0027 0.0024 0.0143
Onchocerca volvulus Peroxidasin homolog 0.0087 0.0241 0.0387
Mycobacterium ulcerans phenolpthiocerol synthesis type-I polyketide synthase PpsE 0.0591 0.2062 0.423
Plasmodium falciparum LCCL domain-containing protein 0.0161 0.051 0.6587
Trypanosoma cruzi heat shock protein 90, putative 0.004 0.0072 0.0744
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0034 0.005 0.0393
Onchocerca volvulus 0.0034 0.005 0.0068
Mycobacterium ulcerans hypothetical protein 0.0094 0.0267 0.0541
Mycobacterium ulcerans polyketide synthase Pks9 0.0591 0.2062 0.423
Onchocerca volvulus Putative organic anion transporter 0.0226 0.0745 0.1228
Loa Loa (eye worm) hypothetical protein 0.0071 0.0185 0.0329
Echinococcus multilocularis nuclear factor of activated T cells 5 0.0165 0.0522 0.0507
Mycobacterium ulcerans non-ribosomal peptide synthetase 0.0095 0.0271 0.0549
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.0126 0.0383 0.0379
Echinococcus granulosus cathepsin L cysteine proteinase 0.0034 0.005 0.0041
Schistosoma mansoni caspase-7 (C14 family) 0.0027 0.0024 0.0021
Mycobacterium ulcerans hypothetical protein 0.0029 0.003 0.0054
Toxoplasma gondii type I fatty acid synthase, putative 0.0966 0.3416 1
Brugia malayi 3-hydroxyacyl-CoA dehydrogenase type II 0.0231 0.0761 0.121
Echinococcus multilocularis gcn5proteinral control of amino acid synthesis 0.029 0.0976 0.0962
Schistosoma mansoni loxhd1 0.0161 0.051 0.0507
Leishmania major heat shock protein 83-1 0.0068 0.0173 0.1699
Onchocerca volvulus 0.0058 0.0136 0.0212
Echinococcus granulosus expressed protein 0.0026 0.0021 0.0011
Leishmania major heat shock protein 83-1 0.0068 0.0173 0.1699
Loa Loa (eye worm) CYP4Cod1 0.0038 0.0063 0.0107
Mycobacterium ulcerans hypothetical protein 0.0071 0.0185 0.0371
Echinococcus multilocularis importin subunit beta 1 0.0034 0.0048 0.0032
Echinococcus multilocularis thyroid hormone receptor alpha 0.0268 0.0894 0.0879
Toxoplasma gondii ATP-dependent Clp endopeptidase, proteolytic subunit ClpP domain-containing protein 0.0094 0.0268 0.0741
Mycobacterium ulcerans polyketide synthase Pks13 0.1368 0.4869 1
Leishmania major mitogen activated protein kinase, putative,map kinase, putative 0.0157 0.0495 0.5175
Trypanosoma brucei Trans-2-enoyl-ACP reductase 2, putative 0.0058 0.0136 0.1588
Trypanosoma cruzi hypothetical protein, conserved 0.0071 0.0185 0.2232
Mycobacterium tuberculosis Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras 0.0116 0.0345 0.0709
Echinococcus granulosus thioredoxin glutathione reductase 0.0046 0.0094 0.0085
Toxoplasma gondii heat shock protein HSP90 0.0068 0.0173 0.0462
Loa Loa (eye worm) hypothetical protein 0.0071 0.0185 0.0329
Mycobacterium tuberculosis Probable oxidoreductase 0.0058 0.0136 0.028
Loa Loa (eye worm) hypothetical protein 0.0087 0.0241 0.0431
Onchocerca volvulus Putative organic anion transporter 0.0226 0.0745 0.1228
Echinococcus granulosus TRP transient receptor potential channel 0.0036 0.0056 0.0047
Leishmania major importin beta-1 subunit, putative 0.0027 0.0025 0.0098
Mycobacterium tuberculosis Probable bacterioferritin BfrA 0.0026 0.0021 0.0042
Echinococcus granulosus GPCR family 2 0.008 0.0214 0.0205
Plasmodium falciparum histone acetyltransferase GCN5 0.0078 0.021 0.2676
Toxoplasma gondii beta-ketoacyl synthase, N-terminal domain-containing protein 0.0605 0.2112 0.6164
Leishmania major trypanothione reductase 0.0046 0.0092 0.082
Mycobacterium ulcerans Type I modular polyketide synthase 0.0907 0.3203 0.6575
Mycobacterium tuberculosis Probable short-chain type dehydrogenase/reductase 0.0231 0.0761 0.1563
Onchocerca volvulus 0.0087 0.0241 0.0387
Trypanosoma brucei heat shock protein 90, putative 0.0068 0.0173 0.2079
Loa Loa (eye worm) hypothetical protein 0.0071 0.0185 0.0329
Trichomonas vaginalis heat shock protein, putative 0.0054 0.0123 0.1096
Loa Loa (eye worm) glycosyl hydrolase family 31 protein 0.0044 0.0085 0.0146
Schistosoma mansoni hypothetical protein 0.008 0.0214 0.0211
Loa Loa (eye worm) hypothetical protein 0.0071 0.0185 0.0329
Loa Loa (eye worm) hypothetical protein 0.0121 0.0365 0.0657
Trypanosoma brucei heat shock protein, putative 0.0068 0.0173 0.2079
Leishmania major heat shock protein 83-1 0.0068 0.0173 0.1699
Trypanosoma cruzi MFS transporter, putative 0.0226 0.0745 0.9638
Trypanosoma cruzi cysteine peptidase, putative 0.0034 0.005 0.0452
Loa Loa (eye worm) latrophilin receptor protein 2 0.008 0.0214 0.0383
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0231 0.0761 0.1556
Mycobacterium tuberculosis Probable membrane bound polyketide synthase Pks6 0.1368 0.4869 1
Loa Loa (eye worm) CXXC zinc finger family protein 0.0029 0.003 0.0047
Brugia malayi acyl carrier protein, mitochondrial precursor, putative 0.0094 0.0267 0.0415
Entamoeba histolytica tyrosyl-DNA phosphodiesterase, putative 0.007 0.0179 0.4687
Trypanosoma brucei mitogen activated protein kinase 4, putative 0.0157 0.0495 0.6333
Loa Loa (eye worm) hypothetical protein 0.0226 0.0745 0.1349
Trypanosoma brucei beta-ketoacyl-ACP synthase 0.0234 0.0772 1
Brugia malayi CXXC zinc finger family protein 0.0029 0.003 0.0033
Mycobacterium ulcerans ATP-dependent Clp protease proteolytic subunit 0.0094 0.0268 0.0542
Mycobacterium tuberculosis Probable polyketide synthase Pks1 0.067 0.2347 0.482
Mycobacterium tuberculosis Phenolpthiocerol synthesis type-I polyketide synthase PpsA 0.0907 0.3203 0.6578
Mycobacterium tuberculosis Probable alcohol dehydrogenase AdhA 0.0058 0.0136 0.028
Mycobacterium tuberculosis NAD(P)H quinone reductase LpdA 0.0116 0.0345 0.0709
Echinococcus granulosus EGFP:Bcl2 fusion protein 0.0087 0.0241 0.0231
Echinococcus granulosus Peptidase C19 ubiquitin carboxyl terminal hydrolase 2 0.0121 0.0365 0.0356
Trypanosoma cruzi transcription factor btf3, putative 0.0036 0.0056 0.0528
Plasmodium vivax vivapain-2 0.0034 0.005 0.0599
Trypanosoma brucei acyl transferase-like protein 0.0059 0.014 0.1633
Mycobacterium tuberculosis Polyketide synthetase MbtC (polyketide synthase) 0.0295 0.0992 0.2038
Trichomonas vaginalis ferritin, putative 0.0026 0.0021 0.0108
Echinococcus multilocularis Malonyl coenzyme A acyl carrier protein transacylase 0.0059 0.014 0.0124
Leishmania major cathepsin L-like protease 0.0034 0.005 0.0369
Toxoplasma gondii thioredoxin reductase 0.0046 0.0092 0.0223
Mycobacterium ulcerans oxidoreductase 0.0058 0.0136 0.0271
Brugia malayi Steroid receptor seven-up type 2 0.0126 0.0383 0.0601
Mycobacterium ulcerans polyketide synthase 0.0907 0.3203 0.6575
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.006 0.0142 0.0126
Leishmania major 4-coumarate:coa ligase-like protein 0.0029 0.003 0.0155
Loa Loa (eye worm) acetyltransferase 0.029 0.0976 0.177
Mycobacterium tuberculosis Probable acyl carrier protein AcpA (ACP) 0.0094 0.0267 0.0549
Trypanosoma brucei heat shock protein, putative 0.0068 0.0173 0.2079
Brugia malayi Hsp90 protein 0.0028 0.0028 0.003
Loa Loa (eye worm) hypothetical protein 0.008 0.0214 0.0383
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.013 0.0397 0.5032
Mycobacterium tuberculosis Probable esterase LipL 0.0071 0.0185 0.038
Schistosoma mansoni aminoadipate-semialdehyde dehydrogenase 0.0088 0.0244 0.024
Loa Loa (eye worm) hypothetical protein 0.006 0.0142 0.0251
Leishmania major phosphopantetheinyl transferase-like protein 0.0025 0.0016 0.0001
Mycobacterium ulcerans zinc-containing alcohol dehydrogenase NAD dependent AdhB 0.0058 0.0136 0.0271
Brugia malayi Glycosyl hydrolases family 31 protein 0.0044 0.0085 0.0121
Brugia malayi Nuclear hormone receptor E75 0.006 0.0142 0.0213
Onchocerca volvulus 0.0071 0.0185 0.0293
Echinococcus multilocularis 3 hydroxyacyl coenzyme A dehydrogenase type 2 0.0231 0.0761 0.0746
Wolbachia endosymbiont of Brugia malayi ACP S-malonyltransferase 0.0059 0.014 0.1632
Schistosoma mansoni hypothetical protein 0.0172 0.0548 0.0545
Trypanosoma brucei heat shock protein, putative 0.0068 0.0173 0.2079
Echinococcus granulosus follistatin 0.0155 0.0485 0.0476
Trypanosoma cruzi cytochrome P450, putative 0.0038 0.0063 0.062
Echinococcus multilocularis short transient receptor potential channel 6 0.0064 0.0157 0.0141
Echinococcus multilocularis Polycystic kidney disease protein 0.0161 0.051 0.0495
Loa Loa (eye worm) animal heme peroxidase 0.0087 0.0241 0.0431
Loa Loa (eye worm) hypothetical protein 0.0126 0.0383 0.0689
Mycobacterium tuberculosis Probable quinone reductase Qor (NADPH:quinone reductase) (zeta-crystallin homolog protein) 0.0058 0.0136 0.028
Chlamydia trachomatis malonyl CoA-ACP transacylase 0.0059 0.014 0.1762
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.008 0.0214 0.0199
Brugia malayi hypothetical protein 0.0161 0.051 0.0806
Plasmodium falciparum conserved Plasmodium protein, unknown function 0.0149 0.0466 0.601
Trichomonas vaginalis alpha-glucosidase, putative 0.0044 0.0085 0.0725
Echinococcus granulosus nuclear factor of activated T cells 5 0.0165 0.0522 0.0513
Schistosoma mansoni hypothetical protein 0.0087 0.0241 0.0237
Trypanosoma brucei metacaspase MCA3 0.0027 0.0024 0.0109
Echinococcus multilocularis RUN 0.0161 0.051 0.0495
Loa Loa (eye worm) hypothetical protein 0.006 0.0142 0.0251
Trichomonas vaginalis glucosylceramidase, putative 0.0141 0.0438 0.4131
Trichomonas vaginalis D-aminoacylase, putative 0.0071 0.0185 0.1691
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.013 0.0397 0.5032
Mycobacterium ulcerans aldehyde dehydrogenase 0.0123 0.0373 0.0758
Echinococcus multilocularis beta LACTamase domain containing family member 0.0071 0.0185 0.0169
Toxoplasma gondii LsmAD domain-containing protein 0.0077 0.0206 0.0558
Trypanosoma brucei Metacaspase-4 0.0027 0.0024 0.0109
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0092 0.026 0.0257
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.004 0.0073 0.0749
Brugia malayi beta-lactamase 0.0071 0.0185 0.0282
Leishmania major 4-coumarate:coa ligase-like protein 0.0029 0.003 0.0155
Echinococcus granulosus endoplasmin 0.0054 0.0123 0.0114
Onchocerca volvulus 0.0226 0.0745 0.1228
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0071 0.0185 0.0329
Giardia lamblia Kinase, CMGC MAPK 0.0157 0.0495 0.5175
Echinococcus granulosus 3 oxoacyl acyl carrier protein synthase 0.0234 0.0772 0.0764
Schistosoma mansoni cpg binding protein 0.003 0.0036 0.0032
Trypanosoma cruzi oxidoreductase, putative 0.0058 0.0136 0.1588
Trichomonas vaginalis heat shock protein, putative 0.0054 0.0123 0.1096
Plasmodium falciparum holo-[acyl-carrier-protein] synthase, putative 0.0025 0.0016 0.0155
Plasmodium vivax heat shock protein, putative 0.0028 0.0028 0.0308
Onchocerca volvulus 0.0034 0.005 0.0068
Trypanosoma cruzi NADP-dependent alcohol hydrogenase, putative 0.0058 0.0136 0.1588
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.008 0.0214 0.0205
Plasmodium falciparum ATP-dependent Clp protease proteolytic subunit 0.0033 0.0044 0.0524
Mycobacterium tuberculosis Phenolpthiocerol synthesis type-I polyketide synthase PpsD 0.0907 0.3203 0.6578
Toxoplasma gondii acyl transferase domain-containing protein 0.0059 0.014 0.0363
Mycobacterium tuberculosis Polyketide synthase Pks13 0.1368 0.4869 1
Mycobacterium ulcerans aldehyde dehydrogenase 0.0123 0.0373 0.0758
Schistosoma mansoni transcription factor LCR-F1 0.0037 0.006 0.0056
Schistosoma mansoni RAR-like nuclear receptor 0.0126 0.0383 0.0379
Schistosoma mansoni hypothetical protein 0.0161 0.051 0.0507
Brugia malayi AMP-binding enzyme family protein 0.0029 0.003 0.0034
Mycobacterium tuberculosis Probable chain -fatty-acid-CoA ligase FadD13 (fatty-acyl-CoA synthetase) 0.0029 0.003 0.0062
Mycobacterium ulcerans exodeoxyribonuclease III protein XthA 0.004 0.0073 0.0141
Schistosoma mansoni acyl carrier protein 0.0094 0.0267 0.0264
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0038 0.0064 0.0524
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0092 0.026 0.0244
Mycobacterium ulcerans phenolpthiocerol synthesis type-I polyketide synthase PpsB 0.0725 0.2545 0.5222
Mycobacterium ulcerans phenolpthiocerol synthesis type-I polyketide synthase PpsD 0.0907 0.3203 0.6575
Loa Loa (eye worm) hypothetical protein 0.0058 0.0136 0.024
Brugia malayi Nuclear hormone receptor-like 1 0.0126 0.0383 0.0601
Mycobacterium leprae Polyketide synthase Pks13 0.1368 0.4869 1
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0126 0.0383 0.0379
Treponema pallidum acyl carrier protein 0.0094 0.0267 0.9964
Onchocerca volvulus 0.0034 0.005 0.0068
Brugia malayi exodeoxyribonuclease III family protein 0.004 0.0073 0.0102
Giardia lamblia TCP-1 chaperonin subunit beta 0.0028 0.0027 0.0115
Loa Loa (eye worm) hypothetical protein 0.0226 0.0745 0.1349
Leishmania major heat shock protein 83-1 0.0068 0.0173 0.1699
Plasmodium falciparum metacaspase 1 0.0027 0.0024 0.0261
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0027 0.0024 0.0143
Brugia malayi nuclear receptor NHR-88 0.006 0.0142 0.0213
Mycobacterium leprae PROBABLE ATP-DEPENDENT CLP PROTEASE PROTEOLYTIC SUBUNIT 2 CLPP2 (ENDOPEPTIDASE CLP 2) 0.0094 0.0268 0.0519
Loa Loa (eye worm) hypothetical protein 0.0126 0.0383 0.0689
Schistosoma mansoni ap endonuclease 0.004 0.0073 0.0069
Onchocerca volvulus 0.0087 0.0241 0.0387
Mycobacterium leprae possible inositol monophosphatase SubH (IMPase) (inositol-1-phosphatase) (I-1-Pase ). 0.0034 0.0049 0.0069
Schistosoma mansoni chaperonin containing t-complex protein 1 beta subunit tcpb 0.0028 0.0027 0.0023
Schistosoma mansoni caspase-3 (C14 family) 0.0101 0.0291 0.0287
Schistosoma mansoni transcription factor btf3 0.0036 0.0056 0.0052
Mycobacterium ulcerans dehydrogenase 0.0058 0.0136 0.0271
Echinococcus granulosus short transient receptor potential channel 6 0.0064 0.0157 0.0148
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD7 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0029 0.003 0.0029
Leishmania major T-complex protein 1, beta subunit, putative 0.0028 0.0027 0.0115
Loa Loa (eye worm) hypothetical protein 0.006 0.0142 0.0251
Trypanosoma cruzi heat shock protein, putative 0.0028 0.0028 0.0156
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0067 0.0168 0.0164
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.013 0.0397 0.5032
Trypanosoma cruzi importin beta-1 subunit, putative 0.0027 0.0025 0.012
Onchocerca volvulus 0.0029 0.003 0.0035
Mycobacterium leprae PROBABLE THIOESTERASE TESA 0.0777 0.2734 0.56
Brugia malayi oxidoreductase, zinc-binding dehydrogenase family protein 0.1742 0.6219 1
Trichomonas vaginalis conserved hypothetical protein 0.0121 0.0365 0.343
Brugia malayi orphan nuclear receptor NR2E1 0.006 0.0142 0.0213
Echinococcus multilocularis follistatin 0.0155 0.0485 0.047
Mycobacterium tuberculosis Possible penicillin-binding protein 0.0456 0.1575 0.3234
Loa Loa (eye worm) hypothetical protein 0.006 0.0142 0.0251
Schistosoma mansoni serine/threonine protein kinase 0.0157 0.0495 0.0492
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.004 0.0073 0.0057
Mycobacterium ulcerans polyketide synthase 0.0965 0.3412 0.7006
Mycobacterium tuberculosis Probable NADH dehydrogenase Ndh 0.0104 0.0303 0.0623
Schistosoma mansoni nuclear receptor nhr-48 0.006 0.0142 0.0138
Toxoplasma gondii histone lysine methyltransferase SET1 0.0062 0.015 0.0394
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.008 0.0214 0.0199
Brugia malayi hypothetical protein 0.0067 0.0168 0.0255
Brugia malayi Nuclear hormone receptor family member nhr-40 0.0126 0.0383 0.0601
Schistosoma mansoni retinoic acid receptor RXR 0.0126 0.0383 0.0379
Echinococcus granulosus mitochondrial trans 2 enoyl coenzyme A reductase 0.0058 0.0136 0.0127
Mycobacterium tuberculosis Probable lipase LipE 0.0071 0.0185 0.038
Loa Loa (eye worm) heat shock protein 75 0.0028 0.0028 0.0043
Trypanosoma brucei oxidoreductase, putative 0.0058 0.0136 0.1588
Echinococcus multilocularis NADH dehydrogenase 0.0094 0.0267 0.0252
Brugia malayi SPARC precursor 0.0155 0.0485 0.0767
Entamoeba histolytica cysteine proteinase, putative 0.0034 0.005 0.1129
Mycobacterium tuberculosis Phenolpthiocerol synthesis type-I polyketide synthase PpsB 0.0143 0.0444 0.0911
Trichomonas vaginalis glucosylceramidase, putative 0.0141 0.0438 0.4131
Brugia malayi Blistered cuticle protein 3 0.0087 0.0241 0.0373
Schistosoma mansoni ubiquitin-specific peptidase 8 (C19 family) 0.0121 0.0365 0.0362
Mycobacterium ulcerans glutaminase 0.031 0.1047 0.2143
Mycobacterium tuberculosis Probable zinc-type alcohol dehydrogenase AdhD (aldehyde reductase) 0.0058 0.0136 0.028
Leishmania major heat shock protein 83-1 0.0068 0.0173 0.1699
Echinococcus granulosus short transient receptor potential channel 6 0.0064 0.0157 0.0148
Loa Loa (eye worm) hypothetical protein 0.006 0.0142 0.0251
Loa Loa (eye worm) hypothetical protein 0.0126 0.0383 0.0689
Echinococcus multilocularis caspase 2 0.0027 0.0024 0.0008
Schistosoma mansoni heat shock protein 0.0068 0.0173 0.017
Mycobacterium ulcerans acyl-CoA synthetase 0.0029 0.003 0.0054
Loa Loa (eye worm) ICD-1 protein 0.0036 0.0056 0.0094
Loa Loa (eye worm) hypothetical protein 0.0126 0.0383 0.0689
Echinococcus multilocularis chaperonin containing TCP1, subunit 2 (beta) 0.0028 0.0027 0.0011
Mycobacterium ulcerans zinc-dependent alcohol dehydrogenase AdhE2 0.0058 0.0136 0.0271
Loa Loa (eye worm) hypothetical protein 0.0226 0.0745 0.1349
Entamoeba histolytica Ran family GTPase 0.0025 0.0016 0.0182
Loa Loa (eye worm) hypothetical protein 0.0087 0.0241 0.0431
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0252 0.0835 0.133
Loa Loa (eye worm) hypothetical protein 0.0037 0.0061 0.0104
Brugia malayi Glycosyl hydrolases family 31 protein 0.0197 0.0638 0.1012
Trichomonas vaginalis heat shock protein, putative 0.0054 0.0123 0.1096
Schistosoma mansoni importin beta-1 0.0034 0.0048 0.0044
Mycobacterium ulcerans polyketide synthase MbtD 0.0287 0.0963 0.197
Mycobacterium ulcerans non-ribosomal peptide synthetase MbtE 0.0103 0.0298 0.0603
Mycobacterium tuberculosis Probable polyketide synthase Pks15 0.0377 0.1289 0.2648
Schistosoma mansoni apoferritin-2 0.0026 0.0021 0.0017
Trichomonas vaginalis cat eye syndrome critical region protein 2, cscr2, putative 0.0085 0.0236 0.2179
Brugia malayi T-complex protein 1, beta subunit 0.0028 0.0027 0.0028
Loa Loa (eye worm) intermediate filament protein 0.0136 0.042 0.0757
Mycobacterium tuberculosis holo-[acyl-carrier protein] synthase AcpS (holo-ACP synthase) (CoA:APO-[ACP]pantetheinephosphotransferase) (CoA:APO-[acyl-carrie 0.0025 0.0016 0.0033
Leishmania major nuclear receptor binding factor-like protein 0.0058 0.0136 0.1298
Giardia lamblia Heat shock protein HSP 90-alpha 0.0068 0.0173 0.1699
Schistosoma mansoni polycystin 1-related 0.0161 0.051 0.0507
Mycobacterium ulcerans 3-oxoacyl-(acyl carrier protein) synthase II 0.0234 0.0772 0.1579
Schistosoma mansoni cathepsin F (C01 family) 0.0023 0.0009 0.0006
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0103 0.0298 0.0464
Brugia malayi Kazal-type serine protease inhibitor domain containing protein 0.0155 0.0485 0.0767
Trichomonas vaginalis conserved hypothetical protein 0.0027 0.0024 0.0143
Loa Loa (eye worm) hypothetical protein 0.0337 0.1144 0.2075
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.006 0.0142 0.0221
Mycobacterium tuberculosis Meromycolate extension acyl carrier protein AcpM 0.0094 0.0267 0.0549
Loa Loa (eye worm) hypothetical protein 0.0143 0.0444 0.08
Trypanosoma cruzi heat shock protein 85, putative 0.0068 0.0173 0.2079
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.008 0.0214 0.033
Schistosoma mansoni ferritin light chain 0.0026 0.0021 0.0017
Mycobacterium ulcerans thioesterase 0.0777 0.2734 0.5611
Mycobacterium ulcerans acyl-CoA synthetase 0.0029 0.003 0.0054
Plasmodium falciparum glutathione reductase 0.0046 0.0092 0.1142
Onchocerca volvulus 0.0029 0.003 0.0034
Plasmodium vivax glutathione reductase, putative 0.0046 0.0092 0.1142
Chlamydia trachomatis acyl carrier protein 0.0094 0.0267 0.3423
Brugia malayi nuclear receptor RXR 0.006 0.0142 0.0213
Loa Loa (eye worm) hypothetical protein 0.0027 0.0024 0.0036
Echinococcus multilocularis 3 oxoacyl (acyl carrier protein) synthase 0.0234 0.0772 0.0758
Trichomonas vaginalis conserved hypothetical protein 0.0027 0.0024 0.0143
Echinococcus granulosus lipoxygenase domain containing protein 0.0161 0.051 0.0501
Mycobacterium ulcerans quinone reductase Qor 0.0058 0.0136 0.0271
Trypanosoma cruzi cysteine peptidase, putative 0.013 0.0397 0.5032
Schistosoma mansoni lipoxygenase 0.0582 0.2028 0.2025
Plasmodium vivax GTP-binding nuclear protein RAN/TC4, putative 0.0025 0.0016 0.0154
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0126 0.0383 0.0601
Echinococcus granulosus heat shock protein 90 0.0068 0.0173 0.0164
Giardia lamblia Histone acetyltransferase GCN5 0.0078 0.021 0.2093
Brugia malayi Papain family cysteine protease containing protein 0.0034 0.005 0.0066
Onchocerca volvulus 0.006 0.0142 0.0221
Loa Loa (eye worm) doublecortin family protein 0.0161 0.051 0.0921
Mycobacterium ulcerans lipase LipD 0.0071 0.0185 0.0371
Leishmania major tyrosyl-DNA phosphodiesterase 1 0.007 0.0179 0.1757
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0034 0.005 0.0393
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.0126 0.0383 0.0367
Entamoeba histolytica cysteine proteinase, putative 0.0034 0.005 0.1129
Onchocerca volvulus 0.0034 0.005 0.0068
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.013 0.0397 0.5032
Loa Loa (eye worm) nuclear receptor NHR-67 0.006 0.0142 0.0251
Giardia lamblia Methyltransferase like 2 0.0281 0.0942 1
Entamoeba histolytica hypothetical protein 0.0036 0.0056 0.1288
Echinococcus multilocularis cathepsin L cysteine protease 0.0034 0.005 0.0034
Schistosoma mansoni zinc binding dehydrogenase 0.0058 0.0136 0.0133
Entamoeba histolytica T-complex protein 1 beta subunit, putative 0.0028 0.0027 0.0476
Entamoeba histolytica acetyltransferase, GNAT family 0.0078 0.021 0.5548
Echinococcus multilocularis tumor protein p63 0.1733 0.6187 0.6181
Trypanosoma cruzi PAB1-binding protein , putative 0.0077 0.0206 0.2509
Schistosoma mansoni rab6-interacting 0.0161 0.051 0.0507
Trichomonas vaginalis ap endonuclease, putative 0.004 0.0073 0.0609
Brugia malayi hypothetical protein 0.006 0.0142 0.0213
Leishmania major hypothetical protein, conserved 0.0059 0.014 0.1334
Plasmodium falciparum cysteine proteinase falcipain 3 0.0034 0.005 0.0599
Chlamydia trachomatis ATP-dependent Clp protease proteolytic subunit 0.0094 0.0268 0.3435
Trypanosoma cruzi hypothetical protein, conserved 0.0044 0.0085 0.0907
Trichomonas vaginalis CMGC family protein kinase 0.0157 0.0495 0.4682
Plasmodium vivax histone acetyltransferase GCN5, putative 0.0085 0.0236 0.3011
Mycobacterium tuberculosis Probable chaperone protein HtpG (heat shock protein) (HSP90 family protein) (high temperature protein G) 0.0054 0.0123 0.0253
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.013 0.0397 0.5032
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.0126 0.0383 0.0689
Schistosoma mansoni inositol monophosphatase 0.0038 0.0064 0.006
Brugia malayi Nuclear hormone receptor family member nhr-3 0.0126 0.0383 0.0601
Mycobacterium ulcerans aldehyde dehydrogenase 0.0123 0.0373 0.0758
Loa Loa (eye worm) hypothetical protein 0.0226 0.0745 0.1349
Brugia malayi Endoplasmin precursor 0.0068 0.0173 0.0264
Brugia malayi Animal haem peroxidase family protein 0.0087 0.0241 0.0373
Brugia malayi glutaminase DH11.1 0.031 0.1047 0.167
Mycobacterium ulcerans NADP-dependent alcohol dehydrogenase AdhC 0.0058 0.0136 0.0271
Leishmania major cathepsin L-like protease 0.013 0.0397 0.4112
Schistosoma mansoni heat shock protein 0.0068 0.0173 0.017
Trypanosoma brucei heat shock protein, putative 0.0068 0.0173 0.2079
Treponema pallidum heat shock protein 90 0.0054 0.0123 0.4246
Mycobacterium tuberculosis Possible dehydrogenase 0.0058 0.0136 0.028
Mycobacterium tuberculosis Possible oxidoreductase FadB5 0.0058 0.0136 0.028
Brugia malayi Animal haem peroxidase family protein 0.0087 0.0241 0.0373
Leishmania major myo-inositol-1(or 4)-monophosphatase 1, putative 0.0038 0.0064 0.0516
Plasmodium vivax hypothetical protein, conserved 0.0027 0.0024 0.0261
Mycobacterium ulcerans phenolpthiocerol synthesis type-I polyketide synthase PpsA 0.0725 0.2545 0.5222
Echinococcus multilocularis sodium:glucose cotransporter 2 0.0037 0.0061 0.0045
Echinococcus granulosus Solute carrier organic anion transporter family 0.0226 0.0745 0.0736
Echinococcus multilocularis cysteine protease 0.0034 0.005 0.0034
Plasmodium falciparum heat shock protein 90, putative 0.0028 0.0028 0.0308
Loa Loa (eye worm) sodium-independent organic anion transporter 0.0226 0.0745 0.1349
Mycobacterium tuberculosis S-nitrosomycothiol reductase MscR 0.0058 0.0136 0.028
Chlamydia trachomatis 3-oxoacyl-ACP synthase 0.0234 0.0772 1
Echinococcus granulosus peroxidasin 0.0087 0.0242 0.0233
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.004 0.0073 0.0125
Onchocerca volvulus 0.0114 0.0338 0.0548
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0231 0.0761 0.1556
Echinococcus multilocularis nuclear receptor nhr 48 0.006 0.0142 0.0126
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.008 0.0214 0.0205
Mycobacterium ulcerans heat shock protein 90 0.0054 0.0123 0.0244
Loa Loa (eye worm) DR-78 0.006 0.0142 0.0251
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0027 0.0025 0.0151
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0034 0.005 0.0393
Toxoplasma gondii HEAT repeat-containing protein 0.0034 0.0048 0.0094
Mycobacterium ulcerans zinc-containing alcohol dehydrogenase NAD-dependent AdhB 0.0058 0.0136 0.0271
Echinococcus granulosus heat shock protein 0.0068 0.0173 0.0164
Giardia lamblia Ubiquitin carboxyl-terminal hydrolase 4 0.0121 0.0365 0.3773
Brugia malayi AMP-binding enzyme family protein 0.0029 0.003 0.0034
Loa Loa (eye worm) hypothetical protein 0.006 0.0142 0.0251
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.0126 0.0383 0.0689
Mycobacterium tuberculosis Probable polyketide beta-ketoacyl synthase Pks3 0.0143 0.0444 0.0911
Schistosoma mansoni hypothetical protein 0.0087 0.0241 0.0237
Schistosoma mansoni tyrosyl-DNA phosphodiesterase 0.007 0.0179 0.0175
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0027 0.0024 0.0143
Mycobacterium tuberculosis Probable NADPH quinone oxidoreductase FadB4 (NADPH:quinone reductase) (zeta-crystallin) 0.0058 0.0136 0.028
Loa Loa (eye worm) hypothetical protein 0.0063 0.0156 0.0276
Brugia malayi MH2 domain containing protein 0.0144 0.0448 0.0706
Loa Loa (eye worm) hypothetical protein 0.0067 0.0168 0.0298
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0115 0.0341 0.0613
Mycobacterium tuberculosis Probable fatty acid synthase Fas (fatty acid synthetase) 0.0293 0.0985 0.2023
Mycobacterium tuberculosis Probable hydrolase 0.0071 0.0185 0.038
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0034 0.005 0.0393
Brugia malayi hypothetical protein 0.006 0.0142 0.0213
Schistosoma mansoni hypothetical protein 0.008 0.0214 0.0211
Plasmodium vivax ATP-dependent Clp protease proteolytic subunit, putative 0.0033 0.0044 0.0524
Trypanosoma cruzi metacaspase, putative 0.0027 0.0024 0.0109
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 8 0.0121 0.0365 0.0356
Brugia malayi Cell death protein 3 precursor 0.0027 0.0024 0.0024
Mycobacterium leprae ATP-dependent Clp protease proteolytic subunit 1 0.0033 0.0044 0.0058
Loa Loa (eye worm) hypothetical protein 0.0023 0.0009 0.001
Echinococcus granulosus ferritin 0.0026 0.0021 0.0011
Trichomonas vaginalis glucosylceramidase, putative 0.0141 0.0438 0.4131
Trypanosoma cruzi metacaspase, putative 0.0027 0.0024 0.0109
Mycobacterium tuberculosis Peptide synthetase MbtF (peptide synthase) 0.0103 0.0298 0.0611
Onchocerca volvulus Cathepsin L homolog 0.0034 0.005 0.0068
Loa Loa (eye worm) tyrosyl-DNA phosphodiesterase 0.007 0.0179 0.0318
Loa Loa (eye worm) hypothetical protein 0.0226 0.0745 0.1349
Brugia malayi Nuclear hormone receptor-like 1 0.0067 0.0168 0.0255
Mycobacterium tuberculosis Probable polyketide synthase Pks7 0.0965 0.3412 0.7008
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0034 0.005 0.0393
Trichomonas vaginalis glutaminase, putative 0.031 0.1047 1
Loa Loa (eye worm) hypothetical protein 0.0087 0.0241 0.0431
Leishmania major heat shock protein 83-1 0.0068 0.0173 0.1699
Brugia malayi Cathepsin L-like precursor 0.0034 0.005 0.0066
Echinococcus granulosus nuclear receptor subfamily 1 group D 0.0067 0.0168 0.0158
Schistosoma mansoni hypothetical protein 0.008 0.0214 0.0211
Echinococcus granulosus retinoic acid receptor rxr beta a 0.0126 0.0383 0.0374
Treponema pallidum ATP-dependent Clp protease proteolytic subunit 0.0094 0.0268 1
Brugia malayi hypothetical protein 0.0087 0.0241 0.0373
Schistosoma mansoni thyroid hormone receptor 0.0268 0.0894 0.0891
Trypanosoma cruzi beta-ketoacyl synthase family protein, putative 0.0234 0.0772 1
Trypanosoma brucei heat shock protein 90, putative 0.0068 0.0173 0.2079
Trichomonas vaginalis alcohol dehydrogenase, putative 0.0058 0.0136 0.1222
Onchocerca volvulus 0.0161 0.051 0.0836
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0044 0.0085 0.0725
Mycobacterium tuberculosis Conserved protein 0.0071 0.0185 0.038
Echinococcus multilocularis mitochondrial trans 2 enoyl coenzyme A reductase 0.0058 0.0136 0.012
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0071 0.0185 0.0181
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0038 0.0064 0.0632
Brugia malayi prostaglandin transporter 0.0226 0.0745 0.1185
Toxoplasma gondii AMP-binding enzyme domain-containing protein 0.0472 0.1633 0.4757
Trichomonas vaginalis conserved hypothetical protein 0.0281 0.0942 0.8987
Mycobacterium tuberculosis Phenolpthiocerol synthesis type-I polyketide synthase PpsE 0.0143 0.0444 0.0911
Trichomonas vaginalis inositol monophosphatase, putative 0.0038 0.0064 0.0524
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.0126 0.0383 0.0689
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.0126 0.0383 0.0379
Mycobacterium leprae Probable oxidireductase 0.0058 0.0136 0.0247
Brugia malayi Nuclear hormone receptor family member nhr-31 0.0126 0.0383 0.0601
Echinococcus granulosus FTZ F1 alpha 0.0126 0.0383 0.0374
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0034 0.005 0.0393
Brugia malayi glutathione reductase 0.0046 0.0092 0.0133
Echinococcus multilocularis expressed protein 0.0155 0.0485 0.047
Leishmania major heat shock protein 83-1 0.0068 0.0173 0.1699
Toxoplasma gondii Zn-containing alcohol dehydrogenase 0.0058 0.0136 0.0353
Leishmania major cathepsin L-like protease 0.0034 0.005 0.0369
Loa Loa (eye worm) hypothetical protein 0.0155 0.0485 0.0876
Plasmodium falciparum heat shock protein 90, putative 0.0028 0.0028 0.0308
Loa Loa (eye worm) glycosyl hydrolase family 31 protein 0.0197 0.0638 0.1153
Onchocerca volvulus Bile acid receptor homolog 0.0126 0.0383 0.0623
Mycobacterium ulcerans bacterioferritin BfrA 0.0026 0.0021 0.0034
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.013 0.0397 0.5032
Brugia malayi hypothetical protein 0.0226 0.0745 0.1185
Loa Loa (eye worm) fibroinase 0.0034 0.005 0.0084
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0121 0.0365 0.0573
Schistosoma mansoni survival motor neuron protein 0.0247 0.0821 0.0817
Loa Loa (eye worm) hypothetical protein 0.006 0.0142 0.0251
Mycobacterium tuberculosis Probable aldehyde dehydrogenase 0.0123 0.0373 0.0766
Loa Loa (eye worm) blistered cuticle protein 3 0.0087 0.0241 0.0431
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0027 0.0025 0.0151
Echinococcus multilocularis AMP dependent ligase 0.0095 0.0271 0.0256
Trichomonas vaginalis glucosylceramidase, putative 0.0093 0.0262 0.2437
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.013 0.0397 0.5032
Mycobacterium tuberculosis Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) 0.004 0.0073 0.0149
Loa Loa (eye worm) hypothetical protein 0.0226 0.0745 0.1349
Brugia malayi conserved hypotetical protein 0.006 0.0142 0.0213
Onchocerca volvulus Chorion peroxidase homolog 0.0087 0.0241 0.0387
Schistosoma mansoni 3-hydroxyacyl-CoA dehydrogenase 0.0231 0.0761 0.0758
Onchocerca volvulus Acyl carrier protein, mitochondrial homolog 0.0094 0.0267 0.043
Onchocerca volvulus 0.0155 0.0485 0.0795
Schistosoma mansoni chaperonin containing t-complex protein 1 beta subunit tcpb 0.0028 0.0027 0.0023
Echinococcus multilocularis caspase 0.0101 0.0291 0.0275
Schistosoma mansoni [ACP] S-malonyltransferase 0.0059 0.014 0.0136
Schistosoma mansoni ferritin light chain 0.0026 0.0021 0.0017
Loa Loa (eye worm) hypothetical protein 0.0126 0.0383 0.0689
Schistosoma mansoni lamin 0.0136 0.042 0.0416
Echinococcus granulosus sodium coupled monocarboxylate transporter 1 0.0037 0.0061 0.0052
Giardia lamblia Heat shock protein HSP 90-alpha 0.0054 0.0123 0.1157
Trichomonas vaginalis glucosylceramidase, putative 0.0093 0.0262 0.2437
Mycobacterium ulcerans acyl-CoA synthetase 0.0029 0.003 0.0054
Loa Loa (eye worm) hypothetical protein 0.0067 0.0168 0.0298
Echinococcus multilocularis mitogen activated protein kinase 3 0.0157 0.0495 0.048
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0038 0.0064 0.0632
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.004 0.0073 0.0063
Mycobacterium leprae PHENOLPTHIOCEROL SYNTHESIS TYPE-I POLYKETIDE SYNTHASE PPSA 0.0907 0.3203 0.6567
Echinococcus multilocularis nuclear receptor subfamily 4 group A 0.006 0.0142 0.0126
Trypanosoma cruzi mitogen activated protein kinase 4, putative 0.0157 0.0495 0.6333
Leishmania major heat shock protein 83-1 0.0068 0.0173 0.1699
Trypanosoma cruzi cytochrome P450, putative 0.0038 0.0063 0.062
Loa Loa (eye worm) animal heme peroxidase 0.0087 0.0241 0.0431
Echinococcus multilocularis endoplasmin 0.0054 0.0123 0.0107
Onchocerca volvulus Peroxidase homolog 0.0087 0.0241 0.0387
Trypanosoma brucei heat shock protein, putative 0.0068 0.0173 0.2079
Trypanosoma cruzi metacaspase, putative 0.0027 0.0024 0.0109
Brugia malayi Thioredoxin reductase 0.0046 0.0092 0.0133
Trichomonas vaginalis set domain proteins, putative 0.013 0.0398 0.3745
Mycobacterium ulcerans beta-lactamase 0.0071 0.0185 0.0371
Trypanosoma cruzi nuclear receptor binding factor, putative 0.0058 0.0136 0.1588
Schistosoma mansoni ferritin 0.0026 0.0021 0.0017
Schistosoma mansoni glutaminase 0.031 0.1047 0.1043
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0092 0.026 0.0404
Echinococcus granulosus sodium:myo inositol cotransporter 0.0037 0.0061 0.0052
Brugia malayi hypothetical protein 0.0226 0.0745 0.1185
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0092 0.026 0.0257
Loa Loa (eye worm) hypothetical protein 0.1213 0.4308 0.7835
Echinococcus multilocularis ubiquitin specific protease 41 0.0121 0.0365 0.035
Echinococcus multilocularis muscleblind protein 1 0.0153 0.0478 0.0463
Echinococcus multilocularis thioredoxin glutathione reductase 0.0046 0.0094 0.0078
Echinococcus granulosus inositol monophosphatase 1 0.0038 0.0064 0.0054
Mycobacterium tuberculosis Inositol-1-monophosphatase SuhB 0.0034 0.0049 0.0102
Leishmania major beta-ketoacyl synthase family protein, putative,3-oxoacyl-acyl carrier protein synthase ii, putative 0.0234 0.0772 0.8171
Echinococcus granulosus cytoplasmic intermediate filament protein 0.0066 0.0165 0.0155
Leishmania major heat shock protein 83-1 0.0068 0.0173 0.1699
Echinococcus granulosus heat shock protein 90 0.0054 0.0123 0.0114
Echinococcus granulosus transient receptor potential ion channel A 0.0093 0.0263 0.0254
Echinococcus multilocularis Peptidase C19, ubiquitin carboxyl terminal hydrolase 2 0.0121 0.0365 0.035
Brugia malayi nuclear receptor RXR 0.0067 0.0168 0.0255
Schistosoma mansoni nuclear hormone receptor 0.0126 0.0383 0.0379
Brugia malayi nuclear hormone receptor family member odr-7 0.006 0.0142 0.0213
Onchocerca volvulus 0.006 0.0142 0.0221
Echinococcus multilocularis caspase 3, apoptosis cysteine peptidase 0.0101 0.0291 0.0275
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.006 0.0142 0.0221
Mycobacterium leprae Probable S-nitrosomycothiol reductase MscR 0.0058 0.0136 0.0247
Mycobacterium ulcerans ATP-dependent Clp protease proteolytic subunit 0.0094 0.0268 0.0542
Brugia malayi latrophilin 2 splice variant baaae 0.0172 0.0548 0.0867
Trypanosoma brucei ubiquitin carboxyl-terminal hydrolase, putative 0.0121 0.0365 0.4617
Trichomonas vaginalis conserved hypothetical protein 0.0036 0.0056 0.0449
Mycobacterium tuberculosis Putative ferredoxin reductase 0.0104 0.0303 0.0623
Echinococcus multilocularis Bcl 2 ous antagonist:killer 0.0087 0.0241 0.0225
Loa Loa (eye worm) hypothetical protein 0.0153 0.0478 0.0863
Onchocerca volvulus 0.0088 0.0244 0.0392
Entamoeba histolytica NADP-dependent alcohol dehydrogenase, putative 0.0058 0.0136 0.3509
Schistosoma mansoni peroxidasin 0.0087 0.0242 0.0238
Loa Loa (eye worm) animal heme peroxidase 0.0087 0.0241 0.0431
Plasmodium vivax ataxin-2 like protein, putative 0.0077 0.0206 0.2625
Plasmodium vivax heat shock protein 86, putative 0.0068 0.0173 0.2201
Schistosoma mansoni nuclear receptor 0.006 0.0142 0.0138
Brugia malayi Kazal-type serine protease inhibitor domain containing protein 0.0155 0.0485 0.0767
Echinococcus multilocularis peptidase Clp (S14 family) 0.0062 0.0151 0.0135
Echinococcus multilocularis Mitotic checkpoint protein PRCC, C terminal 0.0141 0.0438 0.0423
Schistosoma mansoni intermediate filament proteins 0.0136 0.042 0.0416
Leishmania major metacaspase, putative 0.0027 0.0024 0.0089
Leishmania major cysteine peptidase A (CPA) 0.0034 0.005 0.0369
Mycobacterium tuberculosis Conserved protein 0.0071 0.0185 0.038
Echinococcus granulosus chaperonin containing TCP1 subunit 2 beta 0.0028 0.0027 0.0017
Echinococcus granulosus histone acetyltransferase KAT2B 0.0282 0.0947 0.0938
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.0126 0.0383 0.0689
Schistosoma mansoni nuclear hormone receptor 0.006 0.0142 0.0138
Trypanosoma brucei Acyl carrier protein, mitochondrial 0.0094 0.0267 0.332
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0121 0.0365 0.4617
Trypanosoma cruzi acyl transferase-like protein, putative 0.0059 0.014 0.1633
Echinococcus granulosus lamin 0.0136 0.042 0.0411
Onchocerca volvulus 0.088 0.3104 0.5167
Plasmodium vivax ATP-dependent Clp protease proteolytic subunit, putative 0.0094 0.0268 0.3435
Onchocerca volvulus Cathepsin L homolog 0.0034 0.005 0.0068
Leishmania major heat shock protein 83-1 0.0068 0.0173 0.1699
Schistosoma mansoni thyroid hormone receptor 0.0268 0.0894 0.0891
Brugia malayi hypothetical protein 0.0037 0.006 0.0081
Onchocerca volvulus 0.1631 0.582 0.9701
Echinococcus multilocularis inositol monophosphatase 1 0.0038 0.0064 0.0048
Echinococcus multilocularis arachidonate 5 lipoxygenase 0.0582 0.2028 0.2015
Wolbachia endosymbiont of Brugia malayi NADPH:quinone reductase 0.0058 0.0136 0.1587
Schistosoma mansoni ecdysone-induced protein 78c (dr-78) 0.0067 0.0168 0.0164
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0027 0.0024 0.0143
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0034 0.005 0.0393
Mycobacterium tuberculosis Probable polyketide synthase Pks17 0.0228 0.075 0.154
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.0136 0.042 0.0757
Mycobacterium leprae Probable multifunctional mycocerosic acid synthase membrane associated enzyme Mas 0.0965 0.3412 0.6998
Echinococcus granulosus histone acetyltransferase KAT2B 0.0085 0.0236 0.0226
Loa Loa (eye worm) hypothetical protein 0.0136 0.042 0.0757
Echinococcus multilocularis transcription factor btf3 0.0036 0.0056 0.004
Brugia malayi secreted modular calcium-binding protein 1 0.0155 0.0485 0.0767
Schistosoma mansoni inositol monophosphatase 0.0038 0.0064 0.006
Mycobacterium ulcerans acyl carrier protein 0.0094 0.0267 0.0541
Echinococcus multilocularis musashi 0.0136 0.042 0.0404
Brugia malayi oxidoreductase, zinc-binding dehydrogenase family protein 0.0058 0.0136 0.0204
Schistosoma mansoni cathepsin F (C01 family) 0.0034 0.005 0.0047
Onchocerca volvulus 0.0226 0.0745 0.1228
Leishmania major acyl carrier protein, putative 0.0094 0.0267 0.2713
Leishmania major hypothetical protein, conserved 0.0077 0.0206 0.205
Entamoeba histolytica hypothetical protein 0.0037 0.006 0.1392
Echinococcus granulosus ubiquitin specific protease 41 0.0121 0.0365 0.0356
Leishmania major oxidoreductase, putative 0.0058 0.0136 0.1298
Trichomonas vaginalis bromodomain-containing protein, putative 0.0085 0.0236 0.2179
Trypanosoma cruzi cysteine peptidase, clan CA, family C1, cathepsin L-like, putative 0.0119 0.0356 0.4493
Schistosoma mansoni cellular tumor antigen P53 0.0254 0.0843 0.084
Brugia malayi tailless protein 0.006 0.0142 0.0213
Echinococcus multilocularis neutral alpha glucosidase AB 0.0044 0.0085 0.0069
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0034 0.005 0.0393
Mycobacterium tuberculosis NADPH-dependent mycothiol reductase Mtr 0.0046 0.0092 0.0189
Echinococcus granulosus transcription factor Dp 1 0.004 0.0073 0.0063
Trichomonas vaginalis conserved hypothetical protein 0.0027 0.0024 0.0143
Brugia malayi AMP-binding enzyme family protein 0.0029 0.003 0.0034
Schistosoma mansoni lamin 0.0136 0.042 0.0416
Loa Loa (eye worm) hypothetical protein 0.0087 0.0241 0.0431
Toxoplasma gondii hypothetical protein 0.0033 0.0044 0.0084
Brugia malayi AMP-binding enzyme family protein 0.0288 0.0967 0.1542
Schistosoma mansoni hypothetical protein 0.0037 0.006 0.0056
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0034 0.005 0.0393
Loa Loa (eye worm) acyl carrier protein 0.0094 0.0267 0.0479
Brugia malayi GTP-binding nuclear protein RAN/TC4 0.0025 0.0016 0.0011
Schistosoma mansoni apoferritin-2 0.0026 0.0021 0.0017
Echinococcus multilocularis snurportin 1 0.0358 0.1219 0.1205
Echinococcus granulosus mitogen activated protein kinase 0.0157 0.0495 0.0486
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.0126 0.0383 0.0689
Trypanosoma brucei heat shock protein, putative 0.0068 0.0173 0.2079
Wolbachia endosymbiont of Brugia malayi ATP-dependent Clp protease proteolytic subunit 0.0094 0.0268 0.3331
Loa Loa (eye worm) hypothetical protein 0.0096 0.0275 0.0493
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.0126 0.0383 0.0374
Echinococcus granulosus neutral alpha glucosidase AB 0.0044 0.0085 0.0075
Echinococcus granulosus agrin 0.0155 0.0485 0.0476
Schistosoma mansoni transient receptor potential channel 0.0064 0.0157 0.0154
Toxoplasma gondii Kazal-type serine protease inhibitor domain-containing protein 0.0155 0.0485 0.1381
Echinococcus multilocularis ecdysone induced protein 78C 0.0126 0.0383 0.0367
Schistosoma mansoni caspase-7 (C14 family) 0.0101 0.0291 0.0287
Schistosoma mansoni organic anion transporter 0.0226 0.0745 0.0742
Entamoeba histolytica hypothetical protein 0.0037 0.006 0.1392
Mycobacterium tuberculosis P-hydroxybenzoyl-AMP ligase FadD22 0.0103 0.0298 0.0611
Trichomonas vaginalis glucosylceramidase, putative 0.0141 0.0438 0.4131
Onchocerca volvulus 0.0254 0.0843 0.1392
Toxoplasma gondii inositol(myo)-1(or 4)-monophosphatase 2, putative 0.0038 0.0064 0.0141
Loa Loa (eye worm) hypothetical protein 0.0063 0.0156 0.0276
Toxoplasma gondii ABC1 family protein 0.0071 0.0185 0.0496
Echinococcus multilocularis retinoic acid receptor rxr beta a retinoic acid receptor rxr alpha a retinoic acid receptor rxr alpha 0.006 0.0142 0.0126
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0027 0.0024 0.0143
Schistosoma mansoni endoplasmin 0.0068 0.0173 0.017
Plasmodium vivax endoplasmin, putative 0.0068 0.0173 0.2201
Loa Loa (eye worm) hypothetical protein 0.0061 0.0146 0.0257
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0027 0.0024 0.0143
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.013 0.0397 0.5032
Mycobacterium tuberculosis Hypothetical protein 0.0281 0.0942 0.1934
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.0247 0.0821 0.1306
Loa Loa (eye worm) hypothetical protein 0.0155 0.0485 0.0876
Schistosoma mansoni nuclear hormone receptor 0.006 0.0142 0.0138
Loa Loa (eye worm) hypothetical protein 0.0087 0.0241 0.0431
Trypanosoma cruzi metacaspase, putative 0.0027 0.0024 0.0109
Echinococcus multilocularis atpase aaa+ type core atpase aaa type core 0.0789 0.2778 0.2766
Plasmodium falciparum T-complex protein 1 subunit beta 0.0028 0.0027 0.0292
Brugia malayi Nuclear hormone receptor family member nhr-49 0.0126 0.0383 0.0601
Trypanosoma cruzi mitogen activated protein kinase 2, putative 0.0157 0.0495 0.6333
Schistosoma mansoni hypothetical protein 0.0358 0.1219 0.1216
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0252 0.0835 0.1513
Mycobacterium ulcerans oxidoreductase 0.0058 0.0136 0.0271
Toxoplasma gondii exonuclease III APE 0.004 0.0073 0.0166
Loa Loa (eye worm) hypothetical protein 0.0087 0.0241 0.0431
Loa Loa (eye worm) hypothetical protein 0.0058 0.0136 0.024
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0034 0.005 0.0393
Onchocerca volvulus Cell death protein 3 homolog 0.0027 0.0024 0.0025
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0034 0.005 0.0393
Plasmodium falciparum cysteine proteinase falcipain 2a 0.0034 0.005 0.0599
Echinococcus granulosus muscleblind protein 0.0153 0.0478 0.0469
Mycobacterium leprae PROBABLE NADH DEHYDROGENASE NDH 0.0104 0.0303 0.0592
Loa Loa (eye worm) hypothetical protein 0.0252 0.0835 0.1513
Trypanosoma cruzi tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.007 0.0179 0.2151
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0126 0.0383 0.0601
Leishmania major alpha glucosidase II subunit, putative 0.0044 0.0085 0.0741
Toxoplasma gondii Kazal-type serine protease inhibitor domain-containing protein 0.0155 0.0485 0.1381
Echinococcus granulosus arachidonate 5 lipoxygenase 0.0582 0.2028 0.202
Trypanosoma cruzi hypothetical protein, conserved 0.0044 0.0085 0.0907
Plasmodium vivax holo-[acyl-carrier-protein] synthase, putative 0.0025 0.0016 0.0155
Echinococcus multilocularis EGFP:Bcl2 fusion protein 0.0087 0.0241 0.0225
Brugia malayi T-complex protein 1, beta subunit 0.0028 0.0027 0.0028
Echinococcus multilocularis GPCR, family 2 0.008 0.0214 0.0199
Trypanosoma cruzi beta-ketoacyl synthase family protein, putative 0.0234 0.0772 1
Schistosoma mansoni alpha-glucosidase 0.0169 0.0539 0.0535
Entamoeba histolytica acyl-CoA synthetase, putative 0.0095 0.0271 0.7253
Echinococcus granulosus high affinity choline transporter 1 0.0337 0.1144 0.1136
Echinococcus granulosus caspase 0.0101 0.0291 0.0282
Loa Loa (eye worm) hypothetical protein 0.0161 0.051 0.0921
Echinococcus granulosus Polycystic kidney disease protein 0.0161 0.051 0.0501
Echinococcus multilocularis heat shock protein 0.0068 0.0173 0.0157
Entamoeba histolytica hypothetical protein 0.0025 0.0016 0.0185
Trichomonas vaginalis conserved hypothetical protein 0.0027 0.0024 0.0143
Brugia malayi Cytochrome P450 family protein 0.0038 0.0063 0.0086
Toxoplasma gondii transporter, solute:sodium symporter (SSS) family protein 0.0037 0.0061 0.0133
Brugia malayi RNA, U transporter 1 0.0095 0.0271 0.0422
Trypanosoma cruzi transcription factor btf3, putative 0.0036 0.0056 0.0528
Plasmodium vivax vivapain-2 0.0034 0.005 0.0599
Loa Loa (eye worm) hypothetical protein 0.0023 0.0009 0.001
Brugia malayi hypothetical protein 0.1213 0.4308 0.6923
Loa Loa (eye worm) hypothetical protein 0.0087 0.0241 0.0431
Toxoplasma gondii ATP-dependent Clp endopeptidase, proteolytic subunit ClpP domain-containing protein 0.0094 0.0268 0.0741
Loa Loa (eye worm) fatty acid synthase 0.092 0.325 0.591
Onchocerca volvulus Heat shock protein 75 kDa, mitochondrial homolog 0.0028 0.0028 0.0031
Loa Loa (eye worm) hypothetical protein 0.0067 0.0168 0.0298
Loa Loa (eye worm) kazal-type serine protease inhibitor domain-containing protein 0.0155 0.0485 0.0876
Trichomonas vaginalis D-aminoacylase, putative 0.0071 0.0185 0.1691
Plasmodium vivax T-complex protein 1 subunit beta, putative 0.0028 0.0027 0.0292
Leishmania major heat shock protein 83-1 0.0068 0.0173 0.1699
Trypanosoma cruzi Heat shock protein 83, putative 0.0068 0.0173 0.2079
Schistosoma mansoni ap endonuclease 0.004 0.0073 0.0069
Schistosoma mansoni inositol transporter 0.0037 0.0061 0.0058
Wolbachia endosymbiont of Brugia malayi bacterioferritin/cytochrome b1 0.0026 0.0021 0.006
Onchocerca volvulus 0.0058 0.0136 0.0212
Leishmania major heat shock protein 83-1 0.0068 0.0173 0.1699
Loa Loa (eye worm) beta-ketoacyl synthase domain-containing protein 0.0234 0.0772 0.1398
Echinococcus multilocularis heat shock protein 90 0.0068 0.0173 0.0157
Loa Loa (eye worm) inositol-1 0.0038 0.0064 0.0109
Brugia malayi Beta-ketoacyl synthase, N-terminal domain containing protein 0.0907 0.3203 0.5143
Echinococcus multilocularis TRP (transient receptor potential) channel 0.0036 0.0056 0.004
Brugia malayi Cathepsin L-like precursor 0.0034 0.005 0.0066
Echinococcus granulosus acyl carrier protein mitochondrial 0.0094 0.0267 0.0258
Echinococcus granulosus organic anion transporting polypeptide 30B 0.0226 0.0745 0.0736
Onchocerca volvulus 0.0037 0.0061 0.0086
Brugia malayi Nuclear hormone receptor family member nhr-41 0.0126 0.0383 0.0601
Trypanosoma cruzi cysteine peptidase, putative 0.013 0.0397 0.5032
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0044 0.0085 0.0725
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0126 0.0383 0.0367
Brugia malayi Intermediate filament tail domain containing protein 0.0136 0.042 0.0661
Onchocerca volvulus 0.0148 0.0463 0.0758
Brugia malayi Methyltransferase-like protein 4 0.0281 0.0942 0.1501
Mycobacterium ulcerans bacterioferritin BfrB 0.0026 0.0021 0.0034
Mycobacterium ulcerans oxidoreductase FadB5 0.0058 0.0136 0.0271
Onchocerca volvulus 0.0071 0.0185 0.0293
Entamoeba histolytica acyl-coA synthetase, putative 0.0029 0.003 0.0579
Mycobacterium leprae Probable fatty-acid-CoA ligase FadD9 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0095 0.0271 0.0526
Mycobacterium ulcerans fatty acid synthase Fas 0.0293 0.0985 0.2016
Mycobacterium tuberculosis Probable NADP-dependent alcohol dehydrogenase AdhC 0.0058 0.0136 0.028
Entamoeba histolytica cysteine protease, putative 0.0034 0.005 0.1129
Mycobacterium tuberculosis Peptide synthetase MbtE (peptide synthase) 0.0103 0.0298 0.0611
Schistosoma mansoni steroid hormone receptor ad4bp 0.0126 0.0383 0.0379
Brugia malayi Cathepsin L-like precursor 0.0034 0.005 0.0066
Brugia malayi O-Glycosyl hydrolase family 30 protein 0.0141 0.0438 0.069
Leishmania major heat shock protein, putative 0.0028 0.0028 0.0128
Plasmodium vivax malonyl CoA-acyl carrier protein transacylase precursor, putative 0.0059 0.014 0.1762
Echinococcus multilocularis agrin 0.0155 0.0485 0.047
Brugia malayi sodium-independent organic anion transporter family protein 0.0226 0.0745 0.1185
Loa Loa (eye worm) hypothetical protein 0.006 0.0142 0.0251
Mycobacterium tuberculosis Probable multifunctional mycocerosic acid synthase membrane-associated Mas 0.0965 0.3412 0.7008
Plasmodium falciparum acyl carrier protein 0.0094 0.0267 0.3423
Onchocerca volvulus Cathepsin F homolog 0.0034 0.005 0.0068
Trypanosoma brucei importin beta-1 subunit, putative 0.0034 0.0048 0.0423
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0126 0.0383 0.0374
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.0126 0.0383 0.0374
Plasmodium falciparum AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.004 0.0073 0.0891
Toxoplasma gondii histone lysine acetyltransferase GCN5-B 0.0085 0.0236 0.0645
Onchocerca volvulus Putative alcohol dehydrogenase 0.0058 0.0136 0.0212
Loa Loa (eye worm) hypothetical protein 0.0077 0.0206 0.0367
Mycobacterium leprae Probable lipase LipE 0.0071 0.0185 0.0348
Mycobacterium ulcerans cytochrome P450 185A4 Cyp185A4 0.0038 0.0063 0.0121
Trypanosoma brucei T-complex protein 1, beta subunit, putative 0.0028 0.0027 0.014
Treponema pallidum bacterioferrin (TpF1) 0.0026 0.0021 0.018
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0034 0.005 0.0393
Trypanosoma cruzi acyl transferase-like protein 0.0059 0.014 0.1633
Trichomonas vaginalis glucosylceramidase, putative 0.0098 0.028 0.2611
Mycobacterium ulcerans zinc-dependent alcohol dehydrogenase 0.0058 0.0136 0.0271
Onchocerca volvulus Glucosylceramidase homolog 0.0093 0.0262 0.0422
Loa Loa (eye worm) hypothetical protein 0.0497 0.1722 0.3127
Leishmania major ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative 0.0121 0.0365 0.3773
Loa Loa (eye worm) hypothetical protein 0.0226 0.0745 0.1349
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.0126 0.0383 0.0367
Mycobacterium ulcerans 4'-phosphopantetheinyl transferase 0.0025 0.0016 0.0024
Trichomonas vaginalis alpha-glucosidase, putative 0.0044 0.0085 0.0725
Loa Loa (eye worm) thioredoxin reductase 0.0046 0.0092 0.016
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0038 0.0064 0.0524
Loa Loa (eye worm) phosphopantetheine attachment site family protein 0.0094 0.0267 0.0479
Trichomonas vaginalis alcohol dehydrogenase, putative 0.0058 0.0136 0.1222
Trypanosoma brucei hypothetical protein, conserved 0.0025 0.0016 0.0001
Brugia malayi oxidoreductase, zinc-binding dehydrogenase family protein 0.0058 0.0136 0.0204
Trichomonas vaginalis ap endonuclease, putative 0.004 0.0073 0.0609
Echinococcus multilocularis sodium coupled monocarboxylate transporter 1 0.0037 0.0061 0.0045
Entamoeba histolytica exodeoxyribonuclease III, putative 0.004 0.0073 0.175
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD2 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0029 0.003 0.0062
Brugia malayi Muscleblind-like protein 0.0153 0.0478 0.0755
Loa Loa (eye worm) agrin synaptic family protein 0.0155 0.0485 0.0876
Mycobacterium leprae PHENOLPTHIOCEROL SYNTHESIS TYPE-I POLYKETIDE SYNTHASE PPSD 0.0907 0.3203 0.6567
Brugia malayi Cathepsin L-like precursor 0.0034 0.005 0.0066
Trichomonas vaginalis CMGC family protein kinase 0.0157 0.0495 0.4682
Mycobacterium tuberculosis Probable conserved lipoprotein 0.0071 0.0185 0.038
Treponema pallidum ATP-dependent Clp protease proteolytic subunit 0.0033 0.0044 0.1125
Brugia malayi Cathepsin L-like precursor 0.0034 0.005 0.0066
Mycobacterium ulcerans long-chain-fatty-acid-CoA ligase 0.0029 0.003 0.0054
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0034 0.005 0.0393
Echinococcus multilocularis ferritin 0.0026 0.0021 0.0005
Echinococcus granulosus tyrosyl DNA phosphodiesterase 1 0.007 0.0179 0.0169
Echinococcus granulosus nuclear receptor nhr 48 0.006 0.0142 0.0133
Loa Loa (eye worm) hypothetical protein 0.1542 0.5497 1
Trichomonas vaginalis CMGC family protein kinase 0.0157 0.0495 0.4682
Loa Loa (eye worm) MH2 domain-containing protein 0.0144 0.0448 0.0807
Loa Loa (eye worm) nucleolar RNA-associated protein alpha 0.0358 0.1219 0.2212
Echinococcus granulosus lipoxygenase domain containing protein 0.0161 0.051 0.0501
Plasmodium vivax AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.004 0.0073 0.0891
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0034 0.005 0.0393
Leishmania major lipophosphoglycan biosynthetic protein, putative,heat shock protein 90, putative,glucose regulated protein 94, putative 0.0054 0.0123 0.1157
Loa Loa (eye worm) steroid hormone receptor 0.0126 0.0383 0.0689
Schistosoma mansoni apoptosis regulator bax 0.0087 0.0241 0.0237
Echinococcus multilocularis transient receptor potential gamma protein 0.0096 0.0275 0.0259
Chlamydia trachomatis ATP-dependent Clp protease proteolytic subunit 0.0094 0.0268 0.3435
Chlamydia trachomatis holo [acyl-carrier protein] synthase 0.0025 0.0016 0.0155
Loa Loa (eye worm) hypothetical protein 0.0087 0.0241 0.0431
Trypanosoma cruzi metacaspase 5, putative 0.0027 0.0024 0.0109
Leishmania major mitogen activated protein kinase 4, putative;with=GeneDB:LmxM19.1440 0.0157 0.0495 0.5175
Plasmodium vivax heat shock protein 90, putative 0.0028 0.0028 0.0308
Echinococcus multilocularis Nuclear hormone receptor HR96 0.006 0.0142 0.0126
Loa Loa (eye worm) hypothetical protein 0.0034 0.0048 0.008
Brugia malayi mucosa associated lymphoid tissue lymphoma translocation protein 1 0.0027 0.0024 0.0024
Entamoeba histolytica heat shock protein 90, putative 0.0068 0.0173 0.4536
Mycobacterium ulcerans peptide synthetase Nrp (peptide synthase) 0.0103 0.0298 0.0603
Loa Loa (eye worm) cytochrome P450 family protein 0.0038 0.0063 0.0107
Schistosoma mansoni subfamily C14A unassigned peptidase (C14 family) 0.0027 0.0024 0.0021
Brugia malayi Phosphopantetheine attachment site family protein 0.0094 0.0267 0.0415
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0061 0.0148 0.0144
Loa Loa (eye worm) transcription factor SMAD2 0.0144 0.0448 0.0807
Onchocerca volvulus 0.0071 0.0185 0.0293
Echinococcus multilocularis FTZ F1 alpha 0.0126 0.0383 0.0367
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0034 0.005 0.0393
Brugia malayi Cathepsin L-like precursor 0.0034 0.005 0.0066
Wolbachia endosymbiont of Brugia malayi exonuclease III 0.004 0.0073 0.0747
Onchocerca volvulus 0.0136 0.042 0.0685
Loa Loa (eye worm) heat shock protein 90 0.0068 0.0173 0.0308
Mycobacterium leprae DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE 0.0116 0.0345 0.0678
Schistosoma mansoni 3-oxoacyl-[ACP] synthase 0.0234 0.0772 0.0769
Loa Loa (eye worm) hypothetical protein 0.0254 0.0843 0.1527
Echinococcus granulosus Mitotic checkpoint protein PRCC C terminal 0.0141 0.0438 0.0429
Leishmania major heat shock protein 83-1 0.0068 0.0173 0.1699
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0121 0.0365 0.4617
Leishmania major NADP-dependent alcohol dehydrogenase, putative 0.0058 0.0136 0.1298
Loa Loa (eye worm) glutathione reductase 0.0046 0.0092 0.016
Mycobacterium tuberculosis Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB 0.0104 0.0303 0.0623
Mycobacterium tuberculosis Conserved protein 0.0281 0.0942 0.1934
Loa Loa (eye worm) hypothetical protein 0.0126 0.0383 0.0689
Loa Loa (eye worm) hypothetical protein 0.0029 0.003 0.0048
Leishmania major zinc binding dehydrogenase-like protein 0.0058 0.0136 0.1298
Mycobacterium tuberculosis Probable alcohol dehydrogenase Adh 0.0058 0.0136 0.028
Trichomonas vaginalis alpha-glucosidase, putative 0.0044 0.0085 0.0725
Loa Loa (eye worm) hypothetical protein 0.0087 0.0241 0.0431
Brugia malayi Pre-SET motif family protein 0.0115 0.0341 0.0534
Echinococcus multilocularis short transient receptor potential channel 6 0.0064 0.0157 0.0141
Echinococcus granulosus ecdysone induced protein 78C 0.0126 0.0383 0.0374
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.0126 0.0383 0.0379
Leishmania major d-xylulose reductase, putative 0.0058 0.0136 0.1298
Schistosoma mansoni high-affinity choline transporter 0.0337 0.1144 0.1141
Brugia malayi Animal haem peroxidase family protein 0.0087 0.0241 0.0373
Schistosoma mansoni zinc finger protein 0.006 0.0142 0.0138
Leishmania major cathepsin L-like protease 0.0034 0.005 0.0369
Mycobacterium tuberculosis Probable lipase LipD 0.0071 0.0185 0.038
Echinococcus multilocularis lysosomal alpha glucosidase 0.0197 0.0638 0.0623
Echinococcus granulosus 3 hydroxyacyl coenzyme A dehydrogenase type 2 0.0231 0.0761 0.0752
Mycobacterium leprae PROBABLE NADP-DEPENDENT ALCOHOL DEHYDROGENASE ADHC 0.0058 0.0136 0.0247
Loa Loa (eye worm) Papain cysteine protease/cathepsin propeptide inhibitor-containing protein 0.0034 0.005 0.0084
Brugia malayi Kazal-type serine protease inhibitor domain containing protein 0.0155 0.0485 0.0767
Leishmania major oxidoreductase-like protein 0.0058 0.0136 0.1298
Mycobacterium tuberculosis Probable membrane NADH dehydrogenase NdhA 0.0104 0.0303 0.0623
Plasmodium vivax hypothetical protein, conserved 0.0149 0.0466 0.601
Loa Loa (eye worm) cysteine protease 0.0034 0.005 0.0084
Schistosoma mansoni microtubule-associated protein tau 0.2789 1 1
Plasmodium falciparum basic transcription factor 3b, putative 0.0036 0.0056 0.0674
Trypanosoma brucei heat shock protein, putative 0.0068 0.0173 0.2079
Trichomonas vaginalis glucosylceramidase, putative 0.0093 0.0262 0.2437
Echinococcus multilocularis high affinity choline transporter 1 0.0337 0.1144 0.113
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0027 0.0024 0.0143
Brugia malayi nuclear hormone receptor 0.0126 0.0383 0.0601
Schistosoma mansoni hypothetical protein 0.008 0.0214 0.0211
Trypanosoma cruzi tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.007 0.0179 0.2151
Mycobacterium tuberculosis Probable peptide synthetase Nrp (peptide synthase) 0.0103 0.0298 0.0611
Trypanosoma brucei cytochrome P450, putative 0.0038 0.0063 0.062
Mycobacterium tuberculosis Possible quinone oxidoreductase (NADPH:quinone oxidoreductase) (zeta-crystallin) 0.0058 0.0136 0.028
Mycobacterium ulcerans extragenic suppressor protein SuhB 0.0038 0.0064 0.0123
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0092 0.026 0.0466
Mycobacterium tuberculosis Probable polyketide beta-ketoacyl synthase Pks4 0.0143 0.0444 0.0911
Brugia malayi hypothetical protein 0.0148 0.0463 0.0731
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.0126 0.0383 0.0689
Brugia malayi Cytochrome P450 family protein 0.0038 0.0063 0.0086
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0157 0.0495 0.6333
Echinococcus multilocularis heat shock protein 90 0.0054 0.0123 0.0107
Brugia malayi hypothetical protein 0.0067 0.0168 0.0255
Echinococcus multilocularis muscleblind protein 0.0153 0.0478 0.0463
Schistosoma mansoni Tr4/Tr2 (homologue) 0.0126 0.0383 0.0379
Brugia malayi Nuclear hormone receptor family member nhr-14 0.0126 0.0383 0.0601
Echinococcus multilocularis lipoxygenase domain containing protein 0.0161 0.051 0.0495
Schistosoma mansoni transient receptor potential channel 4 0.0096 0.0275 0.0271
Echinococcus multilocularis Acyl carrier protein, mitochondrial 0.0094 0.0267 0.0252
Onchocerca volvulus Fatty acid synthase homolog 0.1681 0.5999 1
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0034 0.005 0.0393
Loa Loa (eye worm) hypothetical protein 0.0036 0.0056 0.0095
Trichomonas vaginalis alcohol dehydrogenase, putative 0.0058 0.0136 0.1222
Loa Loa (eye worm) hypothetical protein 0.0143 0.0444 0.08
Loa Loa (eye worm) GTP-binding nuclear protein RAN/TC4 0.0025 0.0016 0.0022
Brugia malayi Apoptosis regulator proteins, Bcl-2 family protein 0.0087 0.0241 0.0372
Trichomonas vaginalis chaperonin, putative 0.0028 0.0027 0.0166
Mycobacterium ulcerans acyl carrier protein 0.0094 0.0267 0.0541
Mycobacterium leprae PROBABLE POLYKETIDE BETA-KETOACYL SYNTHASE PKS4 0.0143 0.0444 0.0881
Entamoeba histolytica acyl-CoA synthetase, putative 0.0123 0.0371 1
Echinococcus granulosus aldehyde dehydrogenase mitochondrial 0.0123 0.0373 0.0364
Plasmodium falciparum ataxin-2 like protein, putative 0.0077 0.0206 0.2625
Mycobacterium leprae PHENOLPTHIOCEROL SYNTHESIS TYPE-I POLYKETIDE SYNTHASE PPSC 0.0965 0.3412 0.6998
Toxoplasma gondii Kazal-type serine protease inhibitor domain-containing protein 0.0155 0.0485 0.1381
Trichomonas vaginalis ran, putative 0.0025 0.0016 0.0063
Mycobacterium tuberculosis Probable reductase 0.0104 0.0303 0.0623
Schistosoma mansoni cpg binding protein 0.003 0.0036 0.0032
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0027 0.0024 0.0143
Echinococcus multilocularis tyrosyl DNA phosphodiesterase 1 0.007 0.0179 0.0163
Brugia malayi Importin beta-1 subunit 0.0034 0.0048 0.0062
Echinococcus granulosus heat shock protein 75 kDa mitochondrial 0.0028 0.0028 0.0018
Schistosoma mansoni methyltransferase-related 0.0281 0.0942 0.0938
Leishmania major cathepsin L-like protease 0.0034 0.005 0.0369
Trichomonas vaginalis heat shock protein, putative 0.0028 0.0028 0.0178
Leishmania major heat shock protein 83-1 0.0068 0.0173 0.1699
Toxoplasma gondii NAC domain-containing protein 0.0036 0.0056 0.0117
Mycobacterium ulcerans Zn-dependent alcohol dehydrogenase, AdhX 0.0058 0.0136 0.0271
Loa Loa (eye worm) hypothetical protein 0.0027 0.0024 0.0036
Leishmania major 4-coumarate:coa ligase-like protein 0.0029 0.003 0.0155
Loa Loa (eye worm) hypothetical protein 0.0027 0.0024 0.0036
Mycobacterium leprae Probable alcohol dehydrogenase AdhA 0.0058 0.0136 0.0247
Echinococcus granulosus peptidase Clp S14 family 0.0062 0.0151 0.0141
Loa Loa (eye worm) hypothetical protein 0.0059 0.014 0.0246
Trichomonas vaginalis CMGC family protein kinase 0.0157 0.0495 0.4682
Toxoplasma gondii type I fatty acid synthase 0.0143 0.0444 0.1257
Trichomonas vaginalis esterase, putative 0.0071 0.0185 0.1691
Schistosoma mansoni alpha-glucosidase 0.0169 0.0539 0.0535
Echinococcus multilocularis peroxidasin 0.0087 0.0242 0.0226
Brugia malayi cytoplasmic intermediate filament protein 0.0073 0.0191 0.0292
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0037 0.006 0.005
Onchocerca volvulus 0.0034 0.005 0.0068
Loa Loa (eye worm) AMP-binding enzyme family protein 0.088 0.3104 0.5644
Mycobacterium leprae Probable polyketide synthase Pks1 0.0965 0.3412 0.6998
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0126 0.0383 0.0601
Wolbachia endosymbiont of Brugia malayi heat shock protein 90 0.0054 0.0123 0.1414
Schistosoma mansoni organic anion transporter 0.0226 0.0745 0.0742
Mycobacterium ulcerans long-chain-fatty-acid--CoA ligase 0.0029 0.003 0.0054
Loa Loa (eye worm) glutaminase 2 0.031 0.1047 0.1898
Echinococcus granulosus beta LACTamase domain containing family member 0.0071 0.0185 0.0176
Schistosoma mansoni ferritin 0.0026 0.0021 0.0017
Echinococcus multilocularis lamin dm0 0.0136 0.042 0.0404
Schistosoma mansoni hypothetical protein 0.0035 0.0052 0.0048
Trypanosoma cruzi NADP-dependent alcohol hydrogenase, putative 0.0058 0.0136 0.1588
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0034 0.005 0.0393
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.0034 0.005 0.0393
Trypanosoma brucei importin beta-1 subunit, putative 0.0034 0.0048 0.0423
Loa Loa (eye worm) hypothetical protein 0.0134 0.0411 0.074
Echinococcus multilocularis caspase 8 0.0027 0.0024 0.0008
Echinococcus multilocularis lamin 0.0136 0.042 0.0404
Toxoplasma gondii Kazal-type serine protease inhibitor domain-containing protein 0.0155 0.0485 0.1381
Trichomonas vaginalis conserved hypothetical protein 0.0027 0.0024 0.0143
Brugia malayi ecdysteroid receptor 0.0126 0.0383 0.0601
Toxoplasma gondii protease inhibitor PI2 0.0155 0.0485 0.1381
Plasmodium falciparum ATP-dependent Clp protease proteolytic subunit 0.0094 0.0268 0.3435
Brugia malayi Inositol-1 0.0038 0.0064 0.0088
Mycobacterium tuberculosis Probable ATP-dependent CLP protease proteolytic subunit 1 ClpP1 (endopeptidase CLP) 0.0062 0.0151 0.0309
Echinococcus granulosus nuclear receptor subfamily 4 group A 0.006 0.0142 0.0133
Schistosoma mansoni hepatocyte nuclear factor 4-alpha (hnf-4-alpha) 0.006 0.0142 0.0138
Loa Loa (eye worm) animal heme peroxidase 0.0087 0.0241 0.0431
Echinococcus multilocularis sodium:myo inositol cotransporter 0.0037 0.0061 0.0045
Mycobacterium tuberculosis Probable dehydrogenase 0.0104 0.0303 0.0623
Trichomonas vaginalis maltase-glucoamylase, putative 0.0044 0.0085 0.0725
Trypanosoma cruzi NADP-dependent alcohol hydrogenase, putative 0.0058 0.0136 0.1588
Loa Loa (eye worm) hypothetical protein 0.0029 0.003 0.0048
Brugia malayi sodium-independent organic anion transporter family protein 0.0226 0.0745 0.1185
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0027 0.0024 0.0143
Brugia malayi hypothetical protein 0.005 0.0107 0.0157
Brugia malayi ADP-specific Phosphofructokinase/Glucokinase conserved region family protein 0.0059 0.014 0.021
Entamoeba histolytica hypothetical protein 0.0037 0.006 0.1392
Echinococcus granulosus Ataxin 2 N terminaldomain containing protein 0.0035 0.0052 0.0043
Brugia malayi nuclear receptor NHR-67 0.006 0.0142 0.0213
Trypanosoma brucei heat shock protein, putative 0.0068 0.0173 0.2079
Mycobacterium tuberculosis Polyketide synthase Pks12 0.0965 0.3412 0.7008
Toxoplasma gondii cathepsin CPL 0.0034 0.005 0.01
Brugia malayi Probable ClpP-like protease 0.0094 0.0268 0.0416
Giardia lamblia Endonuclease/Exonuclease/phosphatase 0.004 0.0073 0.0612
Loa Loa (eye worm) cytochrome P450 family protein 0.0038 0.0063 0.0107
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.013 0.0397 0.5032
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0037 0.006 0.0044
Echinococcus multilocularis Solute carrier organic anion transporter family 0.0226 0.0745 0.073
Entamoeba histolytica 90 kDa heat shock protein, putative 0.0028 0.0028 0.051
Trypanosoma cruzi heat shock protein 85, putative 0.0054 0.0123 0.1415
Loa Loa (eye worm) hypothetical protein 0.0087 0.0241 0.0431
Trypanosoma brucei oxidoreductase, putative 0.0058 0.0136 0.1588
Mycobacterium ulcerans short-chain dehydrogenase 0.0073 0.0192 0.0387
Schistosoma mansoni [ACP] S-malonyltransferase 0.0059 0.014 0.0136
Mycobacterium ulcerans long-chain fatty-acid CoA ligase 0.0029 0.003 0.0054
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0092 0.026 0.0257
Loa Loa (eye worm) ctsf protein 0.0034 0.005 0.0084
Brugia malayi hypothetical protein 0.0161 0.051 0.0806
Onchocerca volvulus 0.0161 0.051 0.0836
Echinococcus multilocularis survival motor neuron protein 1 0.1213 0.4308 0.4299
Toxoplasma gondii ICE family protease (caspase) p20 domain-containing protein 0.0027 0.0024 0.0024
Trypanosoma cruzi oxidoreductase, putative 0.0058 0.0136 0.1588
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.0071 0.0185 0.038
Brugia malayi Alcohol dehydrogenase class III 0.0058 0.0136 0.0204
Loa Loa (eye worm) hypothetical protein 0.0071 0.0185 0.0329
Brugia malayi nuclear hormone receptor 0.006 0.0142 0.0213
Trypanosoma brucei inositol-1(or 4)-monophosphatase 1, putative 0.0038 0.0064 0.0632
Echinococcus multilocularis cathepsin l cysteine peptidase 0.0034 0.005 0.0034
Loa Loa (eye worm) hypothetical protein 0.0161 0.051 0.0921
Mycobacterium ulcerans phenolpthiocerol synthesis type-I polyketide synthase PpsC 0.0965 0.3412 0.7006
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.0126 0.0383 0.0374
Schistosoma mansoni ferritin 0.0026 0.0021 0.0017
Toxoplasma gondii t-complex protein beta subunit 0.0028 0.0027 0.0031
Echinococcus granulosus transcription factor btf3 0.0036 0.0056 0.0047
Loa Loa (eye worm) T-complex protein 1 0.0028 0.0027 0.0041
Leishmania major basic transcription factor 3a, putative 0.0036 0.0056 0.0432
Brugia malayi Nuclear hormone receptor family member nhr-1 0.0126 0.0383 0.0601
Echinococcus multilocularis organic anion transporting polypeptide 30B 0.0226 0.0745 0.073
Echinococcus granulosus NADH dehydrogenase 0.0094 0.0267 0.0258
Mycobacterium ulcerans phenyloxazoline synthase MbtB 0.0103 0.0298 0.0603
Mycobacterium leprae conserved hypothetical protein 0.0071 0.0185 0.0348
Trypanosoma cruzi heat shock protein 85, putative 0.0068 0.0173 0.2079
Brugia malayi nuclear receptor NHR-88 0.0126 0.0383 0.0601
Schistosoma mansoni ubiquitin-specific peptidase 2 (C19 family) 0.0121 0.0365 0.0362
Mycobacterium ulcerans esterase/lipase LipP 0.0071 0.0185 0.0371
Schistosoma mansoni aldehyde dehydrogenase 0.0123 0.0373 0.0369
Brugia malayi acetyltransferase, GNAT family protein 0.029 0.0976 0.1557
Loa Loa (eye worm) acyl carrier protein 0.0429 0.1476 0.2679
Mycobacterium ulcerans Type I modular polyketide synthase 0.0907 0.3203 0.6575
Plasmodium vivax acyl carrier protein, putative 0.0094 0.0267 0.3423
Schistosoma mansoni hypothetical protein 0.0247 0.0821 0.0817
Trypanosoma brucei trypanothione reductase 0.0046 0.0092 0.1004
Plasmodium falciparum endoplasmin, putative 0.0042 0.0078 0.0961
Brugia malayi Peroxidasin 0.0087 0.0242 0.0374
Trichomonas vaginalis glucosylceramidase, putative 0.0141 0.0438 0.4131
Brugia malayi Animal haem peroxidase family protein 0.0087 0.0241 0.0373
Treponema pallidum exodeoxyribonuclease (exoA) 0.004 0.0073 0.2244
Mycobacterium ulcerans acyl-CoA synthetase 0.0103 0.0298 0.0603
Trichomonas vaginalis chaperonin-60kD, ch60, putative 0.0028 0.0027 0.0166
Wolbachia endosymbiont of Brugia malayi acyl carrier protein 0.0094 0.0267 0.3319
Mycobacterium leprae Probable fatty-acid-CoA synthetase FadD22 (fatty-acid-CoA ligase) (fatty-acid-CoA synthase) 0.0103 0.0298 0.058
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0126 0.0383 0.0601
Trypanosoma cruzi oxidoreductase, putative 0.0058 0.0136 0.1588
Mycobacterium ulcerans NADP-dependent oxidoreductase 0.0058 0.0136 0.0271
Toxoplasma gondii 3-oxoacyl-acyl-carrier protein synthase I/II, putative 0.0234 0.0772 0.2224
Echinococcus multilocularis lipoxygenase domain containing protein 0.0161 0.051 0.0495
Brugia malayi oxidoreductase, zinc-binding dehydrogenase family protein 0.0058 0.0136 0.0204
Plasmodium falciparum ataxin-2 like protein, putative 0.0077 0.0206 0.2625
Echinococcus granulosus importin subunit beta 1 0.0034 0.0048 0.0039
Schistosoma mansoni rab6-interacting 0.0161 0.051 0.0507
Loa Loa (eye worm) hypothetical protein 0.0067 0.0168 0.0298
Brugia malayi photoreceptor-specific nuclear receptor 0.0126 0.0383 0.0601
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0121 0.0365 0.343
Echinococcus multilocularis aldehyde dehydrogenase, mitochondrial 0.0123 0.0373 0.0357
Echinococcus granulosus AMP dependent ligase 0.0095 0.0271 0.0262
Mycobacterium ulcerans 3-oxoacyl-(acyl carrier protein) synthase II 0.0234 0.0772 0.1579
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0034 0.005 0.0393
Brugia malayi aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase 0.0088 0.0244 0.0378
Brugia malayi heat shock protein 90 0.0068 0.0173 0.0264
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0126 0.0383 0.0367
Trichomonas vaginalis heat shock protein, putative 0.0042 0.0078 0.0661
Mycobacterium tuberculosis Probable polyketide synthase Pks5 0.0904 0.3192 0.6556
Echinococcus multilocularis solute carrier family 5 0.0037 0.0061 0.0045
Brugia malayi AMP-binding enzyme family protein 0.088 0.3104 0.4984
Loa Loa (eye worm) nuclear hormone receptor 0.006 0.0142 0.0251
Echinococcus multilocularis lysosomal alpha glucosidase 0.0197 0.0638 0.0623
Trypanosoma cruzi heat shock protein 90, putative 0.0054 0.0123 0.1415
Echinococcus granulosus mitogen activated protein kinase 3 0.0157 0.0495 0.0486
Echinococcus granulosus lamin dm0 0.0136 0.042 0.0411
Schistosoma mansoni ran 0.0025 0.0016 0.0012
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.0126 0.0383 0.0623
Schistosoma mansoni [ACP] S-malonyltransferase 0.0059 0.014 0.0136
Loa Loa (eye worm) hypothetical protein 0.0087 0.0241 0.0431
Trypanosoma brucei Heat shock protein 83, putative 0.0068 0.0173 0.2079
Leishmania major heat shock protein 83-1 0.0068 0.0173 0.1699
Trichomonas vaginalis glucosylceramidase, putative 0.0093 0.0262 0.2437
Brugia malayi Beta-ketoacyl synthase, N-terminal domain containing protein 0.0234 0.0772 0.1229
Mycobacterium tuberculosis Phenyloxazoline synthase MbtB (phenyloxazoline synthetase) 0.088 0.3104 0.6376
Echinococcus multilocularis ATP dependent Clp protease proteolytic subunit 0.0094 0.0268 0.0252
Mycobacterium ulcerans non-ribosomal peptide synthetase MbtF 0.0103 0.0298 0.0603
Echinococcus multilocularis microtubule associated protein 2 0.2789 1 1
Echinococcus multilocularis cpg binding protein 0.003 0.0036 0.002
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0034 0.005 0.0084
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.013 0.0397 0.5032
Trypanosoma cruzi NADP-dependent alcohol hydrogenase, putative 0.0058 0.0136 0.1588
Toxoplasma gondii CMGC kinase, MAPK family (ERK) MAPK-1 0.0157 0.0495 0.1409
Mycobacterium leprae PROBABLE BACTERIOFERRITIN BFRA 0.0026 0.0021 0.0009
Trypanosoma brucei metacaspase 5, putative 0.0027 0.0024 0.0109
Loa Loa (eye worm) cytoplasmic intermediate filament protein 0.0073 0.0191 0.034
Trichomonas vaginalis importin beta-1, putative 0.0027 0.0025 0.0151
Trypanosoma brucei hypothetical protein, conserved 0.0071 0.0185 0.2232
Brugia malayi Kazal-type serine protease inhibitor domain containing protein 0.0155 0.0485 0.0767
Mycobacterium tuberculosis Probable thioesterase TesA 0.0777 0.2734 0.5615
Brugia malayi Nuclear hormone receptor E75 0.006 0.0142 0.0213
Brugia malayi Sodium:solute symporter family protein 0.0037 0.0061 0.0083
Plasmodium falciparum cysteine proteinase falcipain 2b 0.0034 0.005 0.0599
Trypanosoma cruzi trypanothione reductase, putative 0.0046 0.0092 0.1004
Leishmania major hypothetical protein, conserved 0.0281 0.0942 1
Echinococcus multilocularis transient receptor potential ion channel A 0.0093 0.0263 0.0248
Echinococcus granulosus transient receptor potential gamma protein 0.0096 0.0275 0.0266
Trypanosoma cruzi Acyl carrier protein, mitochondrial, putative 0.0094 0.0267 0.332
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.0126 0.0383 0.0374
Echinococcus granulosus sodium:glucose cotransporter 2 0.0037 0.0061 0.0052
Onchocerca volvulus 0.013 0.0398 0.0649
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0029 0.003 0.0054
Schistosoma mansoni ran 0.0025 0.0016 0.0012
Echinococcus granulosus survival motor neuron protein 1 0.1213 0.4308 0.4303
Loa Loa (eye worm) hypothetical protein 0.0034 0.005 0.0084
Echinococcus granulosus cpg binding protein 0.003 0.0036 0.0026
Schistosoma mansoni nuclear hormone receptor superfamily protein-related 0.006 0.0142 0.0138
Trypanosoma cruzi heat shock protein 85, putative 0.0068 0.0173 0.2079
Brugia malayi sodium-independent organic anion transporter family protein 0.0226 0.0745 0.1185
Schistosoma mansoni peroxidasin 0.0087 0.0241 0.0238
Echinococcus multilocularis transcription factor Dp 1 0.004 0.0073 0.0057
Schistosoma mansoni peptidase Clp (S14 family) 0.0094 0.0268 0.0264
Loa Loa (eye worm) hypothetical protein 0.006 0.0142 0.0251
Brugia malayi Doublecortin family protein 0.0161 0.051 0.0806
Schistosoma mansoni endoplasmin 0.0068 0.0173 0.017
Loa Loa (eye worm) hypothetical protein 0.0087 0.0241 0.0431
Schistosoma mansoni inositol transporter 0.0037 0.0061 0.0058
Loa Loa (eye worm) hypothetical protein 0.006 0.0142 0.0251
Leishmania major quinone oxidoreductase, putative 0.0058 0.0136 0.1298
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.0071 0.0185 0.0371
Trichomonas vaginalis conserved hypothetical protein 0.0027 0.0024 0.0143
Schistosoma mansoni alpha glucosidase 0.0044 0.0085 0.0081
Echinococcus granulosus nuclear receptor 2DBD gamma 0.006 0.0142 0.0133
Plasmodium vivax importin-beta 2, putative 0.0034 0.0048 0.057
Plasmodium falciparum metacaspase-like protein 0.0027 0.0024 0.0261
Loa Loa (eye worm) hypothetical protein 0.0087 0.0242 0.0432
Loa Loa (eye worm) hypothetical protein 0.006 0.0142 0.0251
Echinococcus granulosus cathepsin l1 0.0034 0.005 0.0041
Trypanosoma cruzi cysteine peptidase, putative 0.013 0.0397 0.5032
Echinococcus granulosus RUN 0.0161 0.051 0.0501
Mycobacterium leprae PHENOLPTHIOCEROL SYNTHESIS TYPE-I POLYKETIDE SYNTHASE PPSB 0.0725 0.2545 0.5211
Plasmodium falciparum GTP-binding nuclear protein RAN/TC4 0.0025 0.0016 0.0154
Trichomonas vaginalis heat shock protein, putative 0.0068 0.0173 0.1579
Toxoplasma gondii transporter, major facilitator family protein 0.0226 0.0745 0.2144
Schistosoma mansoni follistatin 0.0155 0.0485 0.0482
Brugia malayi GH02984p 0.0337 0.1144 0.1827
Trypanosoma cruzi major cysteine proteinase, putative 0.0102 0.0296 0.3703
Trichomonas vaginalis alpha-glucosidase, putative 0.0044 0.0085 0.0725
Echinococcus multilocularis heat shock protein 75 kDa, mitochondrial 0.0028 0.0028 0.0012
Entamoeba histolytica NADP-dependent alcohol dehydrogenase, putative 0.0058 0.0136 0.3509
Schistosoma mansoni chaperonin containing t-complex protein 1 beta subunit tcpb 0.0028 0.0027 0.0023
Mycobacterium tuberculosis Acyl carrier protein (ACP) MbtL 0.0094 0.0267 0.0549
Trichomonas vaginalis penicillin-binding protein, putative 0.0071 0.0185 0.1691
Loa Loa (eye worm) hypothetical protein 0.0023 0.0009 0.001
Trichomonas vaginalis glucosylceramidase, putative 0.0093 0.0262 0.2437
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.0126 0.0383 0.0367
Loa Loa (eye worm) hypothetical protein 0.0066 0.0165 0.0292
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase domain containing protein 0.0121 0.0365 0.9853
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.0034 0.005 0.0393
Toxoplasma gondii aldehyde dehydrogenase 0.0123 0.0373 0.1049
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0121 0.0365 0.343
Mycobacterium ulcerans zinc-type alcohol dehydrogenase AdhD 0.0058 0.0136 0.0271
Mycobacterium ulcerans quinone oxidoreductase 0.0058 0.0136 0.0271
Plasmodium falciparum importin beta, putative 0.0034 0.0048 0.057
Loa Loa (eye worm) hypothetical protein 0.0094 0.0268 0.048
Schistosoma mansoni agrin 0.0155 0.0485 0.0482
Leishmania major zinc-binding dehydrogenase-like protein 0.0058 0.0136 0.1298
Onchocerca volvulus 0.0247 0.0821 0.1354
Echinococcus multilocularis Nuclear hormone receptor HR96 0.006 0.0142 0.0126
Echinococcus granulosus GTP binding nuclear protein Ran 0.0025 0.0016 0.0007
Trypanosoma cruzi T-complex protein 1, beta subunit, putative 0.0028 0.0027 0.014
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0034 0.005 0.0393
Trypanosoma brucei heat shock protein 84, putative 0.0028 0.0028 0.0156
Echinococcus multilocularis nuclear receptor subfamily 1 group D 0.0067 0.0168 0.0152
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0071 0.0185 0.0181
Brugia malayi Calcitonin receptor-like protein seb-1 0.0252 0.0835 0.133
Echinococcus granulosus lysosomal alpha glucosidase 0.0197 0.0638 0.0629
Mycobacterium ulcerans fatty-acid-CoA ligase FadD9 0.0095 0.0271 0.0549
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0092 0.026 0.0244
Brugia malayi beta-lactamase family protein 0.0071 0.0185 0.0282
Trypanosoma cruzi cruzipain precursor, putative 0.013 0.0397 0.5032
Brugia malayi Latrophilin receptor protein 2 0.008 0.0214 0.033
Schistosoma mansoni nuclear receptor 0.006 0.0142 0.0138
Mycobacterium ulcerans malonyl CoA-acyl carrier protein transacylase FabD 0.0059 0.014 0.0278
Trichomonas vaginalis conserved hypothetical protein 0.0036 0.0056 0.0449
Trypanosoma brucei metacaspase MCA2 0.0027 0.0024 0.0109
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0157 0.0495 0.6333
Schistosoma mansoni transient receptor potential channel 0.0096 0.0275 0.0271
Schistosoma mansoni sodium/solute symporter 0.0037 0.0061 0.0058
Loa Loa (eye worm) CMGC/MAPK/ERK1 protein kinase 0.0157 0.0495 0.0894
Mycobacterium leprae conserved hypothetical protein 0.0094 0.0267 0.0517
Brugia malayi Nuclear hormone receptor-like 1 0.0067 0.0168 0.0255
Brugia malayi nuclear receptor subfamily 1, group D, member 1, putative 0.006 0.0142 0.0213
Brugia malayi hypothetical protein 0.0077 0.0206 0.0316
Plasmodium falciparum heat shock protein 90 0.0068 0.0173 0.2201
Plasmodium falciparum 3-oxoacyl-acyl-carrier protein synthase I/II 0.0234 0.0772 1
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.0126 0.0383 0.0379
Leishmania major cathepsin L-like protease 0.013 0.0397 0.4112
Plasmodium falciparum malonyl CoA-acyl carrier protein transacylase 0.0059 0.014 0.1762
Loa Loa (eye worm) hypothetical protein 0.006 0.0142 0.0251
Plasmodium vivax thioredoxin reductase, putative 0.0046 0.0092 0.1142
Toxoplasma gondii heat shock protein 75, putative 0.0028 0.0028 0.0035
Mycobacterium tuberculosis Conserved protein 0.0071 0.0185 0.038
Loa Loa (eye worm) hypothetical protein 0.0153 0.0478 0.0863
Loa Loa (eye worm) 3-hydroxyacyl-CoA dehydrogenase type II 0.0215 0.0705 0.1276
Mycobacterium leprae PROBABLE FATTY ACID SYNTHASE FAS (FATTY ACID SYNTHETASE) 0.0293 0.0985 0.1997
Toxoplasma gondii histone lysine acetyltransferase GCN5-A 0.0085 0.0236 0.0645
Echinococcus granulosus caspase 2 0.0027 0.0024 0.0015
Onchocerca volvulus Dual oxidase homolog 0.0087 0.0241 0.0387
Trypanosoma brucei protein kinase, putative 0.0157 0.0495 0.6333
Loa Loa (eye worm) hypothetical protein 0.0088 0.0244 0.0437
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0034 0.005 0.0393
Entamoeba histolytica acyl-CoA synthetase, putative 0.0029 0.003 0.0579
Loa Loa (eye worm) hypothetical protein 0.0087 0.0241 0.0431
Schistosoma mansoni heat shock protein 0.0028 0.0028 0.0024
Loa Loa (eye worm) hypothetical protein 0.0126 0.0383 0.0689
Loa Loa (eye worm) hypothetical protein 0.0155 0.0485 0.0876
Onchocerca volvulus 0.0034 0.005 0.0068
Plasmodium vivax hypothetical protein, conserved 0.0071 0.0185 0.2351
Trypanosoma cruzi PAB1-binding protein , putative 0.0077 0.0206 0.2509
Entamoeba histolytica heat shock protein 90, putative 0.0068 0.0173 0.4536
Echinococcus multilocularis cathepsin L cysteine protease 0.0034 0.005 0.0034
Brugia malayi nuclear hormone receptor family member nhr-6 0.006 0.0142 0.0213
Echinococcus granulosus caspase 3 0.0074 0.0194 0.0184
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0071 0.0185 0.0282
Loa Loa (eye worm) nuclear hormone receptor-like 1 0.0067 0.0168 0.0298
Trypanosoma brucei tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.007 0.0179 0.2151
Onchocerca volvulus 0.0136 0.042 0.0685
Echinococcus granulosus sodium:glucose cotransporter 0.0037 0.0061 0.0052
Echinococcus granulosus solute carrier family 5 0.0037 0.0061 0.0052
Loa Loa (eye worm) beta-lactamase 0.0071 0.0185 0.0329
Brugia malayi MAP kinase sur-1 0.0157 0.0495 0.0782
Toxoplasma gondii ICE family protease (caspase) p20 domain-containing protein 0.0027 0.0024 0.0024
Trichomonas vaginalis D-aminoacylase, putative 0.0071 0.0185 0.1691
Trichomonas vaginalis glucosylceramidase, putative 0.0141 0.0438 0.4131
Loa Loa (eye worm) hypothetical protein 0.0071 0.0185 0.0329
Mycobacterium leprae PHENOLPTHIOCEROL SYNTHESIS TYPE-I POLYKETIDE SYNTHASE PPSE 0.0591 0.2062 0.4216
Mycobacterium tuberculosis Possible dehydrogenase 0.0058 0.0136 0.028
Schistosoma mansoni ferritin 0.0026 0.0021 0.0017
Loa Loa (eye worm) O-glycosyl hydrolase family 30 protein 0.0141 0.0438 0.079
Toxoplasma gondii type I fatty acid synthase, putative 0.0664 0.2325 0.6789
Entamoeba histolytica NADP-dependent alcohol dehydrogenase 0.0058 0.0136 0.3509
Schistosoma mansoni hypothetical protein 0.0087 0.0241 0.0237
Loa Loa (eye worm) hypothetical protein 0.0148 0.0463 0.0836
Mycobacterium ulcerans Type I modular polyketide synthase 0.0907 0.3203 0.6575
Brugia malayi Transient-receptor-potential like protein 0.0036 0.0056 0.0076
Loa Loa (eye worm) nuclear receptor nhr-7B 0.006 0.0142 0.0251
Mycobacterium ulcerans NADPH quinone oxidoreductase FadB4 0.0058 0.0136 0.0271
Brugia malayi steroid hormone receptor 0.0126 0.0383 0.0601
Loa Loa (eye worm) hypothetical protein 0.0087 0.0241 0.0431
Loa Loa (eye worm) hypothetical protein 0.006 0.0142 0.0251
Onchocerca volvulus 0.0087 0.0241 0.0387
Echinococcus granulosus intermediate filament protein 0.0136 0.042 0.0411
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD9 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0095 0.0271 0.0557
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.013 0.0397 0.5032
Mycobacterium ulcerans phosphopantetheinyl transferase, PptII 0.0025 0.0016 0.0024
Mycobacterium ulcerans multifunctional mycocerosic acid synthase membrane-associated Mas 0.0965 0.3412 0.7006
Entamoeba histolytica hypothetical protein 0.0027 0.0025 0.0433
Entamoeba histolytica glycosyl hydrolase, family 31 protein 0.0044 0.0085 0.2082
Trypanosoma cruzi nuclear receptor binding factor, putative 0.0058 0.0136 0.1588
Brugia malayi Animal haem peroxidase family protein 0.0087 0.0241 0.0373

Activities

Activity type Activity value Assay description Source Reference
Potency (functional) 2.3934 uM PUBCHEM_BIOASSAY: qHTS profiling assay for firefly luciferase inhibitor/activator using purified enzyme and Km concentrations of substrates (counterscreen for miR-21 project). (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID2288, AID2289, AID2598, AID411] ChEMBL. No reference
Potency (functional) 3.1623 uM PubChem BioAssay. qHTS Assay for Activators of ClpP. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) 3.5481 uM PUBCHEM_BIOASSAY: qHTS for Inhibitors of TGF-b. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID588856, AID588860] ChEMBL. No reference
Potency (functional) = 4.4668 um PUBCHEM_BIOASSAY: qHTS Assay for the Inhibitors of Schistosoma Mansoni Peroxiredoxins. (Class of assay: confirmatory) [Related pubchem assays: 1011 (Confirmation Concentration-Response Assay for Inhibitors of the Schistosoma mansoni Redox Cascade ), 448 (Schistosoma Mansoni Peroxiredoxins (Prx2) and thioredoxin glutathione reductase (TGR) coupled assay)] ChEMBL. No reference
Potency (functional) 4.4668 uM PUBCHEM_BIOASSAY: qHTS for Inhibitors of TGF-b: Cytotox Counterscreen. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID588855, AID588860] ChEMBL. No reference
Potency (functional) 29.0929 uM PUBCHEM_BIOASSAY: Nrf2 qHTS screen for inhibitors. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID493153, AID493163, AID504648] ChEMBL. No reference
Potency (functional) = 39.8107 um PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) 89.1251 uM PUBCHEM_BIOASSAY: qHTS for Inhibitors of Polymerase Iota. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID588623] ChEMBL. No reference

Phenotypes

Whole-cell/tissue/organism interactions

Species name Source Reference Is orphan
Homo sapiens ChEMBL23

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

Bibliographic References

No literature references available for this target.

If you have references for this compound, please enter them in a user comment (below) or Contact us.