TDR Targets

Basic information

Technical information

TDR Targets ID: 1298379
Name: N-[1-(3-nitrophenyl)-3-oxo-3-(prop-2-enylamin o)prop-1-en-2-yl]benzamide
MW: 351.356 | Formula: C19H17N3O4
H donors: 2 H acceptors: 4 LogP: 3.14 Rotable bonds: 9
Rule of 5 violations (Lipinski): 1
SMILES: C=CCNC(=O)/C(=C\c1cccc(c1)[N+](=O)[O-])/NC(=O)c1ccccc1
InChi: 1S/C19H17N3O4/c1-2-11-20-19(24)17(21-18(23)15-8-4-3-5-9-15)13-14-7-6-10-16(12-14)22(25)26/h2-10,12-13H,1,11H2,(H,20,24)(H,21,23)/b17-13+
InChiKey: VPFGPICGSKBJHU-GHRIWEEISA-N

Network

Hover on a compound node to display the structore

Target Layer

Model Organisms

Species	Viewmode
Arabidopsis thaliana
Caenorhabditis elegans
Dictyostelium discoideum
Drosophila melanogaster
Escherichia coli
Homo sapiens
Mus musculus
Oryza sativa
Saccharomyces cerevisiae
Schmidtea mediterranea
Other organisms

TDR Pathogens:

Species	Viewmode
Brugia malayi
Chlamydia trachomatis
Echinococcus granulosus
Entamoeba histolytica
Echinococcus multilocularis
Giardia lamblia
Leishmania major
Loa Loa (eye worm)
Mycobacterium leprae
Mycobacterium tuberculosis
Mycobacterium ulcerans
Onchocerca volvulus
Plasmodium falciparum
Plasmodium vivax
Schistosoma mansoni
Trypanosoma brucei
Trypanosoma cruzi
Toxoplasma gondii
Treponema pallidum
Trichomonas vaginalis
Wolbachia endosymbiont of Brugia malayi

Other Pathogens:

Species	Viewmode
Babesia bovis
Candida albicans
Cryptosporidium hominis
Cryptosporidium parvum
Leishmania braziliensis
Leishmania donovani
Leishmania infantum
Leishmania mexicana
Neospora caninum
Plasmodium berghei
Plasmodium knowlesi
Plasmodium yoelii
Schistosoma japonicum
Trypanosoma brucei gambiense
Trypanosoma congolense
Theileria parva

Compound Layer

This is a work in progress. Come back soon to try this features!

Clustering layers

This is a work in progress. Come back soon to try this features!

Synonyms

N-[(E)-1-(3-nitrophenyl)-3-oxo-3-(prop-2-enylamino)prop-1-en-2-yl]benzamide
N-[1-(allylcarbamoyl)-2-(3-nitrophenyl)vinyl]benzamide
N-[(E)-1-(allylcarbamoyl)-2-(3-nitrophenyl)vinyl]benzamide
N-[1-[(allylamino)-oxomethyl]-2-(3-nitrophenyl)vinyl]benzamide
N-[(E)-1-[(allylamino)-oxomethyl]-2-(3-nitrophenyl)vinyl]benzamide
ZINC05480591
MLS000702632
N-(1-[(allylamino)carbonyl]-2-{3-nitrophenyl}vinyl)benzamide
SMR000225850

Targets

Known targets for this compound

Species	Target name	Source	Bibliographic reference
Homo sapiens	glucagon-like peptide 1 receptor	Starlite/ChEMBL	No references

Predicted pathogen targets for this compound

By orthology

No druggable targets predicted by orthology data

By sequence similarity to non orthologous known druggable targets

Species	Potential target	Known druggable target	Length	Alignment span	Identity
Loa Loa (eye worm)	pigment dispersing factor receptor c	glucagon-like peptide 1 receptor	463 aa	388 aa	25.8 %

Ranking Plot

Putative Targets List

Species	Potential target	Raw	Global	Species
Loa Loa (eye worm)	hypothetical protein	0.0123	0.348	0.348
Loa Loa (eye worm)	hypothetical protein	0.0233	0.751	0.751
Schistosoma mansoni	nuclear hormone receptor	0.011	0.2997	0.2997
Echinococcus multilocularis	nuclear receptor 2DBD gamma	0.011	0.2997	0.2997
Schistosoma mansoni	photoreceptor-specific nuclear receptor related	0.0233	0.751	0.751
Brugia malayi	steroid hormone receptor	0.0233	0.751	0.9964
Mycobacterium ulcerans	fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE	0.0036	0.0271	0.5
Brugia malayi	Nuclear hormone receptor family member nhr-19	0.0233	0.751	0.9964
Echinococcus multilocularis	Nuclear hormone receptor family member nhr 41	0.0233	0.751	0.751
Brugia malayi	Iron-sulfur cluster assembly accessory protein	0.0048	0.0715	0.0948
Brugia malayi	nuclear receptor NHR-88	0.011	0.2997	0.3976
Onchocerca volvulus	Nuclear receptor subfamily 6 group A member 1 homolog	0.011	0.2997	0.3765
Loa Loa (eye worm)	hypothetical protein	0.018	0.5577	0.5577
Schistosoma mansoni	nuclear receptor	0.011	0.2997	0.2997
Brugia malayi	tailless protein	0.011	0.2997	0.3976
Echinococcus multilocularis	FTZ F1 nuclear receptor protein	0.0233	0.751	0.751
Loa Loa (eye worm)	hypothetical protein	0.011	0.2997	0.2997
Loa Loa (eye worm)	hypothetical protein	0.011	0.2997	0.2997
Brugia malayi	latrophilin 2 splice variant baaae	0.0041	0.0474	0.063
Echinococcus multilocularis	beta LACTamase domain containing family member	0.0036	0.0271	0.0271
Loa Loa (eye worm)	hypothetical protein	0.011	0.2997	0.2997
Brugia malayi	ecdysteroid receptor	0.0233	0.751	0.9964
Loa Loa (eye worm)	hypothetical protein	0.0123	0.348	0.348
Schistosoma mansoni	survival motor neuron protein	0.0048	0.0715	0.0715
Schistosoma mansoni	Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein)	0.0055	0.0991	0.0991
Echinococcus multilocularis	nuclear receptor subfamily 4 group A	0.011	0.2997	0.2997
Brugia malayi	beta-lactamase family protein	0.0036	0.0271	0.036
Brugia malayi	nuclear hormone receptor	0.0233	0.751	0.9964
Loa Loa (eye worm)	hypothetical protein	0.0123	0.348	0.348
Brugia malayi	Nuclear hormone receptor family member nhr-40	0.0233	0.751	0.9964
Echinococcus multilocularis	retinoic acid receptor rxr beta a retinoic acid receptor rxr alpha a retinoic acid receptor rxr alpha	0.011	0.2997	0.2997
Echinococcus granulosus	nuclear receptor 2DBD gamma	0.011	0.2997	0.2997
Echinococcus granulosus	Nuclear hormone receptor HR96	0.011	0.2997	0.2997
Echinococcus granulosus	nuclear receptor 2DBD gamma	0.0233	0.751	0.751
Brugia malayi	hypothetical protein	0.011	0.2997	0.3976
Trypanosoma cruzi	hypothetical protein, conserved	0.0036	0.0271	0.5
Trichomonas vaginalis	D-aminoacylase, putative	0.0036	0.0271	0.5
Echinococcus multilocularis	nuclear receptor subfamily 1 group D	0.0123	0.348	0.348
Echinococcus granulosus	hepatocyte nuclear factor 4 alpha	0.0233	0.751	0.751
Brugia malayi	Nuclear hormone receptor family member nhr-41	0.0233	0.751	0.9964
Schistosoma mansoni	ecdysone-induced protein 78c (dr-78)	0.0123	0.348	0.348
Echinococcus multilocularis	nuclear receptor 2DBD gamma	0.0233	0.751	0.751
Loa Loa (eye worm)	hypothetical protein	0.018	0.5577	0.5577
Echinococcus granulosus	nuclear receptor 2DBD gamma	0.0233	0.751	0.751
Loa Loa (eye worm)	nuclear hormone receptor family member nhr-49	0.0233	0.751	0.751
Schistosoma mansoni	nuclear hormone receptor nor-1/nor-2	0.0233	0.751	0.751
Echinococcus granulosus	survival motor neuron protein 1	0.0234	0.7537	0.7537
Loa Loa (eye worm)	hypothetical protein	0.0233	0.751	0.751
Loa Loa (eye worm)	hypothetical protein	0.0123	0.348	0.348
Schistosoma mansoni	FTZ-F1 nuclear receptor-like protein	0.0233	0.751	0.751
Mycobacterium ulcerans	beta-lactamase	0.0036	0.0271	0.5
Brugia malayi	Nuclear hormone receptor E75	0.011	0.2997	0.3976
Echinococcus granulosus	nuclear receptor subfamily 4 group A	0.011	0.2997	0.2997
Schistosoma mansoni	steroid hormone receptor ad4bp	0.0233	0.751	0.751
Brugia malayi	Muscleblind-like protein	0.018	0.5577	0.7399
Echinococcus multilocularis	Nuclear hormone receptor HR96	0.011	0.2997	0.2997
Loa Loa (eye worm)	hypothetical protein	0.011	0.2997	0.2997
Loa Loa (eye worm)	hypothetical protein	0.0036	0.0271	0.0271
Brugia malayi	Nuclear hormone receptor-like 1	0.0233	0.751	0.9964
Schistosoma mansoni	RAR-like nuclear receptor	0.0233	0.751	0.751
Echinococcus granulosus	ecdysone induced protein 78C	0.0233	0.751	0.751
Brugia malayi	Nuclear hormone receptor family member nhr-3	0.0233	0.751	0.9964
Brugia malayi	Ligand-binding domain of nuclear hormone receptor family protein	0.0233	0.751	0.9964
Loa Loa (eye worm)	hypothetical protein	0.0036	0.0271	0.0271
Schistosoma mansoni	nuclear receptor 2DBD-gamma	0.0233	0.751	0.751
Schistosoma mansoni	Tr4/Tr2 (homologue)	0.0233	0.751	0.751
Loa Loa (eye worm)	GTP-binding regulatory protein Gs alpha-S chain	0.0055	0.0991	0.0991
Loa Loa (eye worm)	hypothetical protein	0.0036	0.0271	0.0271
Echinococcus granulosus	FTZ F1 alpha	0.0233	0.751	0.751
Loa Loa (eye worm)	hypothetical protein	0.011	0.2997	0.2997
Schistosoma mansoni	family S12 unassigned peptidase (S12 family)	0.0036	0.0271	0.0271
Echinococcus granulosus	thyroid hormone receptor alpha	0.011	0.2997	0.2997
Brugia malayi	Nuclear hormone receptor family member nhr-31	0.0233	0.751	0.9964
Brugia malayi	hypothetical protein	0.0123	0.348	0.4617
Loa Loa (eye worm)	hypothetical protein	0.0036	0.0271	0.0271
Brugia malayi	Nuclear hormone receptor family member nhr-49	0.0233	0.751	0.9964
Brugia malayi	nuclear receptor subfamily 1, group D, member 1, putative	0.011	0.2997	0.3976
Echinococcus granulosus	FTZ F1 nuclear receptor protein	0.0233	0.751	0.751
Echinococcus granulosus	nuclear receptor nhr 48	0.011	0.2997	0.2997
Brugia malayi	Nuclear hormone receptor family member nhr-25	0.0233	0.751	0.9964
Trichomonas vaginalis	D-aminoacylase, putative	0.0036	0.0271	0.5
Mycobacterium leprae	conserved hypothetical protein	0.0036	0.0271	0.5
Brugia malayi	orphan nuclear receptor NR2E1	0.011	0.2997	0.3976
Brugia malayi	Nuclear hormone receptor-like 1	0.0123	0.348	0.4617
Mycobacterium tuberculosis	Possible penicillin-binding protein	0.0228	0.7304	1
Schistosoma mansoni	Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein)	0.0055	0.0991	0.0991
Schistosoma mansoni	family S12 unassigned peptidase (S12 family)	0.0036	0.0271	0.0271
Echinococcus multilocularis	hepatocyte nuclear factor 4 alpha	0.0233	0.751	0.751
Schistosoma mansoni	nuclear hormone receptor	0.0233	0.751	0.751
Echinococcus multilocularis	survival motor neuron protein 1	0.0234	0.7537	0.7537
Echinococcus multilocularis	COUP TF:Svp nuclear hormone receptor	0.0233	0.751	0.751
Onchocerca volvulus	Bile acid receptor homolog	0.0233	0.751	1
Toxoplasma gondii	ABC1 family protein	0.0036	0.0271	1
Loa Loa (eye worm)	nuclear hormone receptor-like 1	0.0123	0.348	0.348
Brugia malayi	Nuclear hormone receptor E75	0.011	0.2997	0.3976
Brugia malayi	GTP-binding regulatory protein Gs alpha-S chain, putative	0.0055	0.0991	0.1314
Brugia malayi	Nuclear hormone receptor family member nhr-14	0.0233	0.751	0.9964
Echinococcus multilocularis	snurportin 1	0.0301	1	1
Plasmodium vivax	hypothetical protein, conserved	0.0036	0.0271	1
Schistosoma mansoni	nuclear receptor	0.011	0.2997	0.2997
Echinococcus multilocularis	nuclear receptor nhr 48	0.011	0.2997	0.2997
Onchocerca volvulus		0.011	0.2997	0.3765
Loa Loa (eye worm)	nuclear hormone receptor family member nhr-41	0.0233	0.751	0.751
Loa Loa (eye worm)	beta-LACTamase domain containing family member	0.0036	0.0271	0.0271
Loa Loa (eye worm)	nuclear hormone receptor	0.011	0.2997	0.2997
Brugia malayi	nuclear hormone receptor	0.011	0.2997	0.3976
Loa Loa (eye worm)	hypothetical protein	0.0233	0.751	0.751
Loa Loa (eye worm)	nuclear hormone receptor family member nhr-1	0.0233	0.751	0.751
Brugia malayi	Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative	0.0036	0.0271	0.036
Loa Loa (eye worm)	nucleolar RNA-associated protein alpha	0.0301	1	1
Loa Loa (eye worm)	DR-78	0.011	0.2997	0.2997
Loa Loa (eye worm)	hypothetical protein	0.011	0.2997	0.2997
Trichomonas vaginalis	D-aminoacylase, putative	0.0036	0.0271	0.5
Loa Loa (eye worm)	hypothetical protein	0.0233	0.751	0.751
Loa Loa (eye worm)	nuclear receptor nhr-7B	0.011	0.2997	0.2997
Loa Loa (eye worm)	hypothetical protein	0.011	0.2997	0.2997
Loa Loa (eye worm)	steroid hormone receptor	0.0233	0.751	0.751
Brugia malayi	nuclear hormone receptor family member nhr-6	0.011	0.2997	0.3976
Brugia malayi	RNA, U transporter 1	0.008	0.1906	0.2528
Brugia malayi	beta-lactamase family protein	0.0036	0.0271	0.036
Schistosoma mansoni	thyroid hormone receptor	0.0233	0.751	0.751
Plasmodium falciparum	importin beta, putative	0.0028	0	0.5
Trichomonas vaginalis	penicillin-binding protein, putative	0.0036	0.0271	0.5
Echinococcus granulosus	guanine nucleotide binding protein Gs subunit	0.0055	0.0991	0.0991
Loa Loa (eye worm)	hypothetical protein	0.011	0.2997	0.2997
Loa Loa (eye worm)	hypothetical protein	0.011	0.2997	0.2997
Loa Loa (eye worm)	hypothetical protein	0.011	0.2997	0.2997
Loa Loa (eye worm)	hypothetical protein	0.0036	0.0271	0.0271
Onchocerca volvulus		0.0233	0.751	1
Onchocerca volvulus	Protein ultraspiracle homolog	0.0233	0.751	1
Brugia malayi	Nuclear hormone receptor family member nhr-1	0.0233	0.751	0.9964
Schistosoma mansoni	nuclear hormone receptor	0.011	0.2997	0.2997
Schistosoma mansoni	zinc finger protein	0.011	0.2997	0.2997
Schistosoma mansoni	hepatocyte nuclear factor 4-alpha (hnf-4-alpha)	0.011	0.2997	0.2997
Loa Loa (eye worm)	hypothetical protein	0.0123	0.348	0.348
Brugia malayi	beta-lactamase	0.0036	0.0271	0.036
Loa Loa (eye worm)	hypothetical protein	0.0036	0.0271	0.0271
Echinococcus granulosus	retinoic acid receptor rxr beta a	0.0233	0.751	0.751
Echinococcus multilocularis	thyroid hormone receptor alpha	0.0233	0.751	0.751
Echinococcus granulosus	nuclear receptor subfamily 1 group D	0.0123	0.348	0.348
Loa Loa (eye worm)	hypothetical protein	0.0233	0.751	0.751
Schistosoma mansoni	hypothetical protein	0.0048	0.0715	0.0715
Echinococcus multilocularis	Nuclear hormone receptor HR96	0.011	0.2997	0.2997
Echinococcus multilocularis	guanine nucleotide binding protein G(s) subunit	0.0055	0.0991	0.0991
Mycobacterium ulcerans	esterase/lipase LipP	0.0036	0.0271	0.5
Echinococcus multilocularis	ecdysone induced protein 78C	0.0233	0.751	0.751
Echinococcus granulosus	guanine nucleotide binding protein Gs subunit	0.0055	0.0991	0.0991
Schistosoma mansoni	hypothetical protein	0.0041	0.0474	0.0474
Trypanosoma brucei	hypothetical protein, conserved	0.0036	0.0271	1
Schistosoma mansoni	coup transcription factor	0.0233	0.751	0.751
Brugia malayi	conserved hypotetical protein	0.011	0.2997	0.3976
Echinococcus multilocularis	FTZ F1 alpha	0.0233	0.751	0.751
Loa Loa (eye worm)	hypothetical protein	0.0041	0.0474	0.0474
Echinococcus multilocularis	guanine nucleotide binding protein G(s) subunit	0.0055	0.0991	0.0991
Brugia malayi	Ligand-binding domain of nuclear hormone receptor family protein	0.0233	0.751	0.9964
Onchocerca volvulus		0.0048	0.0715	0.0612
Brugia malayi	nuclear receptor RXR	0.011	0.2997	0.3976
Schistosoma mansoni	hypothetical protein	0.0301	1	1
Brugia malayi	nuclear receptor RXR	0.0123	0.348	0.4617
Schistosoma mansoni	nuclear hormone receptor superfamily protein-related	0.011	0.2997	0.2997
Brugia malayi	Nuclear hormone receptor family member nhr-25	0.0233	0.751	0.9964
Echinococcus granulosus	muscleblind protein	0.018	0.5577	0.5577
Echinococcus granulosus	Nuclear hormone receptor family member nhr 41	0.0233	0.751	0.751
Loa Loa (eye worm)	hypothetical protein	0.0234	0.7537	0.7537
Brugia malayi	Steroid receptor seven-up type 2	0.0233	0.751	0.9964
Onchocerca volvulus	Nuclear receptor subfamily 6 group A member 1 homolog	0.011	0.2997	0.3765
Loa Loa (eye worm)	nuclear Hormone Receptor family member	0.0233	0.751	0.751
Echinococcus granulosus	COUP TF:Svp nuclear hormone receptor	0.0233	0.751	0.751
Loa Loa (eye worm)	hypothetical protein	0.0233	0.751	0.751
Mycobacterium ulcerans	lipase LipD	0.0036	0.0271	0.5
Brugia malayi	Corticotropin releasing factor receptor 2 precursor, putative	0.006	0.1172	0.1556
Onchocerca volvulus		0.011	0.2997	0.3765
Mycobacterium leprae	Probable lipase LipE	0.0036	0.0271	0.5
Loa Loa (eye worm)	nuclear hormone receptor family member nhr-14	0.0233	0.751	0.751
Echinococcus granulosus	Nuclear hormone receptor HR96	0.011	0.2997	0.2997
Loa Loa (eye worm)	hypothetical protein	0.011	0.2997	0.2997
Brugia malayi	hypothetical protein	0.011	0.2997	0.3976
Brugia malayi	nuclear receptor NHR-67	0.011	0.2997	0.3976
Loa Loa (eye worm)	hypothetical protein	0.011	0.2997	0.2997
Brugia malayi	photoreceptor-specific nuclear receptor	0.0233	0.751	0.9964
Echinococcus multilocularis	muscleblind protein 1	0.018	0.5577	0.5577
Onchocerca volvulus	Steroid hormone receptor family member cnr14 homolog	0.0233	0.751	1
Echinococcus multilocularis	muscleblind protein	0.018	0.5577	0.5577
Schistosoma mansoni	Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein)	0.0055	0.0991	0.0991
Schistosoma mansoni	retinoid-x-receptor (RXR)	0.0123	0.348	0.348
Loa Loa (eye worm)	hypothetical protein	0.011	0.2997	0.2997
Brugia malayi	hypothetical protein	0.0123	0.348	0.4617
Loa Loa (eye worm)	hypothetical protein	0.0233	0.751	0.751
Brugia malayi	nuclear hormone receptor family member odr-7	0.011	0.2997	0.3976
Brugia malayi	Calcitonin receptor-like protein seb-1	0.006	0.1172	0.1556
Trichomonas vaginalis	esterase, putative	0.0036	0.0271	0.5
Trypanosoma cruzi	hypothetical protein, conserved	0.0036	0.0271	0.5
Loa Loa (eye worm)	nuclear receptor NHR-67	0.011	0.2997	0.2997
Loa Loa (eye worm)	pigment dispersing factor receptor c	0.006	0.1172	0.1172
Echinococcus multilocularis	nuclear receptor 2DBD gamma	0.0233	0.751	0.751
Trichomonas vaginalis	penicillin-binding protein, putative	0.0036	0.0271	0.5
Loa Loa (eye worm)	nuclear hormone receptor family member nhr-31	0.0233	0.751	0.751
Schistosoma mansoni	thyroid hormone receptor	0.0233	0.751	0.751
Loa Loa (eye worm)	hypothetical protein	0.006	0.1172	0.1172
Loa Loa (eye worm)	nuclear hormone receptor family member nhr-40	0.0233	0.751	0.751
Echinococcus granulosus	beta LACTamase domain containing family member	0.0036	0.0271	0.0271
Schistosoma mansoni	retinoic acid receptor RXR	0.0233	0.751	0.751
Brugia malayi	Nuclear hormone receptor-like 1	0.0123	0.348	0.4617
Brugia malayi	Nuclear hormone receptor family member nhr-19	0.0233	0.751	0.9964
Brugia malayi	hypothetical protein	0.0234	0.7537	1
Schistosoma mansoni	nuclear receptor nhr-48	0.011	0.2997	0.2997
Loa Loa (eye worm)	beta-lactamase	0.0036	0.0271	0.0271
Brugia malayi	nuclear receptor NHR-88	0.0233	0.751	0.9964
Mycobacterium ulcerans	hypothetical protein	0.0036	0.0271	0.5
Loa Loa (eye worm)	hypothetical protein	0.0233	0.751	0.751
Schistosoma mansoni	retinoid-x-receptor (RXR)	0.0233	0.751	0.751
Brugia malayi	ecdysone receptor	0.011	0.2997	0.3976
Leishmania major	hypothetical protein, conserved	0.0036	0.0271	0.5

Activities

Activity type	Activity value	Assay description	Source	Reference
Potency (functional)	6.3096 uM	PubChem BioAssay. qHTS of GLP-1 Receptor Inverse Agonists (Inhibition Mode). (Class of assay: confirmatory)	ChEMBL.	No reference
Potency (functional)	23.1093 uM	PubChem BioAssay. A quantitative high throughput screen for small molecules that induce DNA re-replication in MCF 10a normal breast cells. (Class of assay: confirmatory)	ChEMBL.	No reference
Potency (binding)	39.8107 uM	PubChem BioAssay. qHTS Assay for Inhibitors of MBNL1-poly(CUG) RNA binding. (Class of assay: confirmatory)	ChEMBL.	No reference

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?

In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.

In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

ChEMBL: CHEMBL1407020

Bibliographic References

No literature references available for this target.

If you have references for this compound, please enter them in a user comment (below) or Contact us.

Detailed information for compound 1298379