Detailed information for compound 1300326

Basic information

Technical information
  • TDR Targets ID: 1300326
  • Name: (5E)-1-(furan-2-ylmethyl)-5-[(E)-3-furan-2-yl prop-2-enylidene]-3-propan-2-yl-1,3-diazinane -2,4,6-trione
  • MW: 354.357 | Formula: C19H18N2O5
  • H donors: 0 H acceptors: 3 LogP: 2.47 Rotable bonds: 5
    Rule of 5 violations (Lipinski): 1
  • SMILES: CC(N1C(=O)/C(=C/C=C/c2ccco2)/C(=O)N(C1=O)Cc1ccco1)C
  • InChi: 1S/C19H18N2O5/c1-13(2)21-18(23)16(9-3-6-14-7-4-10-25-14)17(22)20(19(21)24)12-15-8-5-11-26-15/h3-11,13H,12H2,1-2H3/b6-3+,16-9+
  • InChiKey: NOFSRFCBRFFHJD-KJWHQMAJSA-N  


Substructure search Similarity search

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Synonyms

  • (5E)-1-(2-furylmethyl)-5-[(E)-3-(2-furyl)prop-2-enylidene]-3-isopropyl-hexahydropyrimidine-2,4,6-trione
  • (5E)-1-(2-furylmethyl)-5-[(E)-3-(2-furyl)prop-2-enylidene]-3-isopropylhexahydropyrimidine-2,4,6-trione
  • (5E)-1-(2-furylmethyl)-5-[(E)-3-(2-furyl)prop-2-enylidene]-3-isopropyl-barbituric acid
  • ZINC00984570
  • 1-(2-furylmethyl)-5-[3-(2-furyl)-2-propenylidene]-3-isopropyl-2,4,6(1H,3H,5H)-pyrimidinetrione
  • MLS000543527
  • SMR000163947

Targets

Known targets for this compound

Species Target name Source Bibliographic reference
Homo sapiens polymerase (DNA directed) iota Starlite/ChEMBL No references
Homo sapiens Wolf-Hirschhorn syndrome candidate 1 Starlite/ChEMBL No references
Homo sapiens neuropeptide S receptor 1 Starlite/ChEMBL No references
Homo sapiens K(lysine) acetyltransferase 2A Starlite/ChEMBL No references
Homo sapiens glucagon-like peptide 1 receptor Starlite/ChEMBL No references
Homo sapiens apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3D Starlite/ChEMBL No references
Homo sapiens Werner syndrome, RecQ helicase-like Starlite/ChEMBL No references
Homo sapiens ubiquitin specific peptidase 2 Starlite/ChEMBL No references
Homo sapiens GNAS complex locus Starlite/ChEMBL No references
Homo sapiens polymerase (DNA directed), eta Starlite/ChEMBL No references
Homo sapiens arachidonate 15-lipoxygenase, type B Starlite/ChEMBL No references
Schistosoma mansoni Thioredoxin glutathione reductase Starlite/ChEMBL No references
Homo sapiens heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) Starlite/ChEMBL No references
Homo sapiens DNA (cytosine-5-)-methyltransferase 1 Starlite/ChEMBL No references
Homo sapiens RecQ helicase-like Starlite/ChEMBL No references
Homo sapiens Bloom syndrome, RecQ helicase-like Starlite/ChEMBL No references
Homo sapiens transmembrane protease, serine 15 Starlite/ChEMBL No references
Homo sapiens polo-like kinase 1 Starlite/ChEMBL No references
Homo sapiens geminin, DNA replication inhibitor Starlite/ChEMBL No references
Homo sapiens microphthalmia-associated transcription factor Starlite/ChEMBL No references
Homo sapiens l(3)mbt-like 1 (Drosophila) Starlite/ChEMBL No references
Homo sapiens microtubule-associated protein tau Starlite/ChEMBL No references
Homo sapiens lysine (K)-specific demethylase 4A Starlite/ChEMBL No references

Predicted pathogen targets for this compound

By orthology
Species Potential target Known druggable target/s Ortholog Group
Leishmania donovani heat-shock protein hsp70, putative Get druggable targets OG5_126588 All targets in OG5_126588
Echinococcus multilocularis arachidonate 5 lipoxygenase Get druggable targets OG5_127482 All targets in OG5_127482
Schistosoma mansoni SET domain protein Get druggable targets OG5_130029 All targets in OG5_130029
Leishmania braziliensis protein kinase, putative,polo-like protein kinase, putative Get druggable targets OG5_127396 All targets in OG5_127396
Echinococcus multilocularis Heat shock 70 kDa protein 4 Get druggable targets OG5_126588 All targets in OG5_126588
Entamoeba histolytica recQ family DNA helicase Get druggable targets OG5_126644 All targets in OG5_126644
Trypanosoma cruzi glucose-regulated protein 78, putative Get druggable targets OG5_126588 All targets in OG5_126588
Echinococcus granulosus heat shock protein 70 Get druggable targets OG5_126588 All targets in OG5_126588
Plasmodium yoelii heat shock protein 70 Get druggable targets OG5_126588 All targets in OG5_126588
Plasmodium knowlesi histone acetyltransferase GCN5, putative Get druggable targets OG5_127781 All targets in OG5_127781
Echinococcus granulosus heat shock protein 70 Get druggable targets OG5_126588 All targets in OG5_126588
Echinococcus granulosus heat shock protein 70 Get druggable targets OG5_126588 All targets in OG5_126588
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) Get druggable targets OG5_131088 All targets in OG5_131088
Babesia bovis thiodoxin reductase, putative Get druggable targets OG5_126785 All targets in OG5_126785
Plasmodium berghei heat shock protein 70 Get druggable targets OG5_126588 All targets in OG5_126588
Echinococcus granulosus heat shock protein 70 Get druggable targets OG5_126588 All targets in OG5_126588
Entamoeba histolytica heat shock protein70, hsp70A2, putative Get druggable targets OG5_126588 All targets in OG5_126588
Leishmania donovani heat shock protein 70-related protein Get druggable targets OG5_126588 All targets in OG5_126588
Echinococcus granulosus heat shock protein 70 Get druggable targets OG5_126588 All targets in OG5_126588
Schistosoma japonicum ko:K06631 polo-like kinase 1, putative Get druggable targets OG5_127396 All targets in OG5_127396
Loa Loa (eye worm) glutathione reductase Get druggable targets OG5_126785 All targets in OG5_126785
Echinococcus multilocularis heat shock protein 70 Get druggable targets OG5_126588 All targets in OG5_126588
Echinococcus multilocularis heat shock protein 71 kDa protein Get druggable targets OG5_126588 All targets in OG5_126588
Trichomonas vaginalis heat shock protein, putative Get druggable targets OG5_126588 All targets in OG5_126588
Echinococcus granulosus Transcription factor JmjC domain containing protein Get druggable targets OG5_127917 All targets in OG5_127917
Echinococcus granulosus thioredoxin glutathione reductase Get druggable targets OG5_126785 All targets in OG5_126785
Echinococcus multilocularis jumonji domain containing protein Get druggable targets OG5_127917 All targets in OG5_127917
Plasmodium yoelii glutathione reductase Get druggable targets OG5_126785 All targets in OG5_126785
Schistosoma mansoni serine/threonine protein kinase Get druggable targets OG5_127396 All targets in OG5_127396
Schistosoma japonicum hypothetical protein Get druggable targets OG5_127431 All targets in OG5_127431
Trypanosoma cruzi trypanothione reductase, putative Get druggable targets OG5_126785 All targets in OG5_126785
Echinococcus granulosus Heat shock 70 kDa protein 4 Get druggable targets OG5_126588 All targets in OG5_126588
Trichomonas vaginalis cat eye syndrome critical region protein 2, cscr2, putative Get druggable targets OG5_127781 All targets in OG5_127781
Schistosoma mansoni jumonji domain containing protein Get druggable targets OG5_127917 All targets in OG5_127917
Echinococcus granulosus 3'partial|5'partial|heat shock protein 70 Get druggable targets OG5_126588 All targets in OG5_126588
Plasmodium yoelii ATP-dependent DNA helicase-related Get druggable targets OG5_126644 All targets in OG5_126644
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 8 Get druggable targets OG5_127431 All targets in OG5_127431
Leishmania mexicana trypanothione reductase Get druggable targets OG5_126785 All targets in OG5_126785
Leishmania infantum ATP-dependent DEAD/H DNA helicase recQ, putative Get druggable targets OG5_126644 All targets in OG5_126644
Leishmania donovani trypanothione reductase Get druggable targets OG5_126785 All targets in OG5_126785
Plasmodium yoelii heat shock protein Get druggable targets OG5_126588 All targets in OG5_126588
Schistosoma mansoni blooms syndrome DNA helicase Get druggable targets OG5_126644 All targets in OG5_126644
Plasmodium falciparum ATP-dependent DNA helicase Q1 Get druggable targets OG5_126644 All targets in OG5_126644
Trypanosoma cruzi heat shock protein 70 (hsp70), putative Get druggable targets OG5_126588 All targets in OG5_126588
Echinococcus multilocularis ubiquitin specific protease 41 Get druggable targets OG5_127431 All targets in OG5_127431
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_133408 All targets in OG5_133408
Echinococcus multilocularis neuropeptide s receptor Get druggable targets OG5_136011 All targets in OG5_136011
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_127917 All targets in OG5_127917
Trypanosoma cruzi ATP-dependent DEAD/H DNA helicase recQ, putative Get druggable targets OG5_126644 All targets in OG5_126644
Leishmania major heat-shock protein hsp70, putative Get druggable targets OG5_126588 All targets in OG5_126588
Trichomonas vaginalis heat shock protein 70 (HSP70)-4, putative Get druggable targets OG5_126588 All targets in OG5_126588
Trichomonas vaginalis heat shock protein, putative Get druggable targets OG5_126588 All targets in OG5_126588
Cryptosporidium hominis thioredoxin reductase Get druggable targets OG5_126785 All targets in OG5_126785
Leishmania major ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative Get druggable targets OG5_127431 All targets in OG5_127431
Leishmania mexicana ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative Get druggable targets OG5_127431 All targets in OG5_127431
Neospora caninum Heat shock protein 70, related Get druggable targets OG5_126588 All targets in OG5_126588
Echinococcus multilocularis Get druggable targets OG5_126588 All targets in OG5_126588
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative Get druggable targets OG5_127431 All targets in OG5_127431
Echinococcus granulosus jumonji domain containing protein Get druggable targets OG5_127917 All targets in OG5_127917
Echinococcus granulosus microtubule associated protein 2 Get druggable targets OG5_133504 All targets in OG5_133504
Loa Loa (eye worm) acetyltransferase Get druggable targets OG5_127781 All targets in OG5_127781
Echinococcus granulosus heat shock protein 70b Get druggable targets OG5_126588 All targets in OG5_126588
Entamoeba histolytica heat shock protein70, hsp70A2, putative Get druggable targets OG5_126588 All targets in OG5_126588
Candida albicans ubiquitin-specific protease Get druggable targets OG5_127431 All targets in OG5_127431
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit Get druggable targets OG5_131088 All targets in OG5_131088
Candida albicans bromodomain protein similar to S. cerevisiae GCN5 (YGR252W) histone acetyltransferase Get druggable targets OG5_127781 All targets in OG5_127781
Leishmania infantum trypanothione reductase Get druggable targets OG5_126785 All targets in OG5_126785
Giardia lamblia Histone acetyltransferase GCN5 Get druggable targets OG5_127781 All targets in OG5_127781
Echinococcus granulosus heat shock protein 70 Get druggable targets OG5_126588 All targets in OG5_126588
Echinococcus granulosus heat shock protein 70 Get druggable targets OG5_126588 All targets in OG5_126588
Leishmania infantum protein kinase, putative,polo-like protein kinase, putative Get druggable targets OG5_127396 All targets in OG5_127396
Trichomonas vaginalis CAMK family protein kinase Get druggable targets OG5_127396 All targets in OG5_127396
Neospora caninum MGC84926 protein, related Get druggable targets OG5_126785 All targets in OG5_126785
Schistosoma mansoni heat shock protein 70 Get druggable targets OG5_126588 All targets in OG5_126588
Theileria parva histone acetyltransferase Gcn5, putative Get druggable targets OG5_127781 All targets in OG5_127781
Theileria parva heat shock protein 70 Get druggable targets OG5_126588 All targets in OG5_126588
Echinococcus multilocularis heat shock protein 70 related Get druggable targets OG5_126588 All targets in OG5_126588
Cryptosporidium hominis heat shock protein Get druggable targets OG5_126588 All targets in OG5_126588
Trypanosoma cruzi DNA polymerase eta, putative Get druggable targets OG5_128521 All targets in OG5_128521
Cryptosporidium parvum protein with 4 PHD domains plus a SET domain and associated cysteine cluster at the C-terminus Get druggable targets OG5_130029 All targets in OG5_130029
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative Get druggable targets OG5_131088 All targets in OG5_131088
Brugia malayi Thioredoxin reductase Get druggable targets OG5_126785 All targets in OG5_126785
Leishmania major heat shock protein 70-related protein Get druggable targets OG5_126588 All targets in OG5_126588
Plasmodium berghei histone acetyltransferase GCN5, putative Get druggable targets OG5_127781 All targets in OG5_127781
Loa Loa (eye worm) heat shock 70kDa protein 5 Get druggable targets OG5_126588 All targets in OG5_126588
Leishmania braziliensis DNA polymerase eta, putative Get druggable targets OG5_128521 All targets in OG5_128521
Toxoplasma gondii ImpB/MucB/SamB family protein Get druggable targets OG5_128521 All targets in OG5_128521
Trypanosoma brucei gambiense polo-like protein kinase,protein kinase Get druggable targets OG5_127396 All targets in OG5_127396
Echinococcus multilocularis ATP dependent DNA helicase Q5 Get druggable targets OG5_126644 All targets in OG5_126644
Cryptosporidium hominis hypothetical protein Get druggable targets OG5_130029 All targets in OG5_130029
Leishmania braziliensis ATP-dependent DEAD/H DNA helicase recQ, putative Get druggable targets OG5_126644 All targets in OG5_126644
Candida albicans one of two closely related potential jumonji-like transcription factor genes similar to S. cerevisiae RPH1 (YER169W) damage-resp Get druggable targets OG5_127917 All targets in OG5_127917
Entamoeba histolytica heat shock protein 70 family Get druggable targets OG5_126588 All targets in OG5_126588
Echinococcus multilocularis heat shock protein 70 related Get druggable targets OG5_126588 All targets in OG5_126588
Echinococcus multilocularis endonuclease exonuclease phosphatase Get druggable targets OG5_130415 All targets in OG5_130415
Leishmania infantum DNA polymerase eta, putative Get druggable targets OG5_128521 All targets in OG5_128521
Cryptosporidium parvum DinB/family X-type DNA polymerase Get druggable targets OG5_128521 All targets in OG5_128521
Plasmodium knowlesi heat shock protein, putative Get druggable targets OG5_126588 All targets in OG5_126588
Echinococcus granulosus heat shock protein 70 Get druggable targets OG5_126588 All targets in OG5_126588
Trypanosoma brucei luminal binding protein 1 (BiP), putative Get druggable targets OG5_126588 All targets in OG5_126588
Brugia malayi glutathione reductase Get druggable targets OG5_126785 All targets in OG5_126785
Schistosoma japonicum Histone-lysine N-methyltransferase NSD3, putative Get druggable targets OG5_130029 All targets in OG5_130029
Candida albicans similar to S. cerevisiae DNA polymerase pol-eta, involved in the bypass of distorted DNA lesions Get druggable targets OG5_128521 All targets in OG5_128521
Loa Loa (eye worm) thioredoxin reductase Get druggable targets OG5_126785 All targets in OG5_126785
Echinococcus granulosus heat shock protein 70 Get druggable targets OG5_126588 All targets in OG5_126588
Entamoeba histolytica serine/threonine protein kinase, putative Get druggable targets OG5_127396 All targets in OG5_127396
Echinococcus multilocularis Heat shock 70 kDa protein Get druggable targets OG5_126588 All targets in OG5_126588
Toxoplasma gondii thioredoxin reductase Get druggable targets OG5_126785 All targets in OG5_126785
Entamoeba histolytica heat shock protein70, hsp70A2, putative Get druggable targets OG5_126588 All targets in OG5_126588
Neospora caninum Bromodomain containing protein, related Get druggable targets OG5_127781 All targets in OG5_127781
Brugia malayi serine/threonine-protein kinase plk-2 Get druggable targets OG5_127396 All targets in OG5_127396
Plasmodium knowlesi ADP-dependent DNA helicase RecQ, putative Get druggable targets OG5_126644 All targets in OG5_126644
Echinococcus multilocularis heat shock protein 70 Get druggable targets OG5_126588 All targets in OG5_126588
Candida albicans heat shock protein 70 Get druggable targets OG5_126588 All targets in OG5_126588
Trypanosoma cruzi polo-like protein kinase, putative Get druggable targets OG5_127396 All targets in OG5_127396
Echinococcus multilocularis transcription factor eb Get druggable targets OG5_133408 All targets in OG5_133408
Echinococcus granulosus heat shock protein 70 Get druggable targets OG5_126588 All targets in OG5_126588
Echinococcus multilocularis heat shock protein Get druggable targets OG5_126588 All targets in OG5_126588
Leishmania major protein kinase, putative,polo-like protein kinase, putative Get druggable targets OG5_127396 All targets in OG5_127396
Giardia lamblia Kinase, PLK Get druggable targets OG5_127396 All targets in OG5_127396
Schistosoma japonicum expressed protein Get druggable targets OG5_127431 All targets in OG5_127431
Candida albicans similar to S. cerevisiae GLR1 (YPL091W) glutathione oxidoreductase Get druggable targets OG5_126785 All targets in OG5_126785
Plasmodium vivax ADP-dependent DNA helicase RecQ, putative Get druggable targets OG5_126644 All targets in OG5_126644
Echinococcus multilocularis neuropeptide receptor A26 Get druggable targets OG5_136011 All targets in OG5_136011
Trypanosoma congolense ubiquitin carboxyl-terminal hydrolase, putative Get druggable targets OG5_127431 All targets in OG5_127431
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein Get druggable targets OG5_126644 All targets in OG5_126644
Schistosoma japonicum Lethal(3)malignant brain tumor-like 4 protein, putative Get druggable targets OG5_130415 All targets in OG5_130415
Leishmania braziliensis trypanothione reductase Get druggable targets OG5_126785 All targets in OG5_126785
Leishmania infantum heat-shock protein hsp70, putative Get druggable targets OG5_126588 All targets in OG5_126588
Echinococcus multilocularis heat shock protein 70 related Get druggable targets OG5_126588 All targets in OG5_126588
Candida albicans one of two closely related potential jumonji-like transcription factor genes similar to S. cerevisiae RPH1 (YER169W) damage-resp Get druggable targets OG5_127917 All targets in OG5_127917
Trypanosoma congolense heat shock 70 kDa protein, putative Get druggable targets OG5_126588 All targets in OG5_126588
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_126644 All targets in OG5_126644
Plasmodium berghei ADP-dependent DNA helicase RecQ, putative Get druggable targets OG5_126644 All targets in OG5_126644
Echinococcus granulosus heat shock protein 70 Get druggable targets OG5_126588 All targets in OG5_126588
Schistosoma japonicum ko:K03509 DNA polymerase eta subunit, putative Get druggable targets OG5_128521 All targets in OG5_128521
Echinococcus multilocularis dna polymerase eta Get druggable targets OG5_128521 All targets in OG5_128521
Trypanosoma brucei gambiense heat shock 70 kDa protein, putative Get druggable targets OG5_126588 All targets in OG5_126588
Echinococcus multilocularis Peptidase C19, ubiquitin carboxyl terminal hydrolase 2 Get druggable targets OG5_127431 All targets in OG5_127431
Entamoeba histolytica heat shock protein 70, putative Get druggable targets OG5_126588 All targets in OG5_126588
Leishmania mexicana DNA polymerase eta, putative Get druggable targets OG5_128521 All targets in OG5_128521
Candida albicans one of two closely related potential jumonji-like transcription factor genes similar to S. cerevisiae RPH1 (YER169W) damage-resp Get druggable targets OG5_127917 All targets in OG5_127917
Theileria parva heat shock protein 70, putative Get druggable targets OG5_126588 All targets in OG5_126588
Echinococcus granulosus Heat shock 70 kDa protein 4 Get druggable targets OG5_126588 All targets in OG5_126588
Trichomonas vaginalis heat shock protein 70 (HSP70)-4, putative Get druggable targets OG5_126588 All targets in OG5_126588
Echinococcus granulosus heat shock protein 70 Get druggable targets OG5_126588 All targets in OG5_126588
Plasmodium berghei thioredoxin reductase, putative Get druggable targets OG5_126785 All targets in OG5_126785
Loa Loa (eye worm) ATP-dependent DNA helicase Get druggable targets OG5_126644 All targets in OG5_126644
Brugia malayi Bloom's syndrome protein homolog Get druggable targets OG5_126644 All targets in OG5_126644
Trypanosoma brucei gambiense glucose-regulated protein 78, putative,luminal binding protein 1 (BiP), putative Get druggable targets OG5_126588 All targets in OG5_126588
Echinococcus multilocularis Get druggable targets OG5_126588 All targets in OG5_126588
Trichomonas vaginalis CAMK family protein kinase Get druggable targets OG5_127396 All targets in OG5_127396
Entamoeba histolytica 70 kDa heat shock protein, putative Get druggable targets OG5_126588 All targets in OG5_126588
Babesia bovis heat shock protein 70 precursor, putative Get druggable targets OG5_126588 All targets in OG5_126588
Echinococcus granulosus heat shock protein 71 kDa protein Get druggable targets OG5_126588 All targets in OG5_126588
Onchocerca volvulus Get druggable targets OG5_126588 All targets in OG5_126588
Echinococcus multilocularis Heat shock protein 70 (HSP70) Get druggable targets OG5_126588 All targets in OG5_126588
Neospora caninum hypothetical protein Get druggable targets OG5_126644 All targets in OG5_126644
Leishmania major trypanothione reductase Get druggable targets OG5_126785 All targets in OG5_126785
Echinococcus granulosus heat shock protein 70 Get druggable targets OG5_126588 All targets in OG5_126588
Leishmania major glucose-regulated protein 78, putative Get druggable targets OG5_126588 All targets in OG5_126588
Echinococcus granulosus heat shock protein 70 Get druggable targets OG5_126588 All targets in OG5_126588
Cryptosporidium hominis heat shock protein 70 precursor Get druggable targets OG5_126588 All targets in OG5_126588
Brugia malayi ImpB/MucB/SamB family protein Get druggable targets OG5_128521 All targets in OG5_128521
Trypanosoma brucei heat shock protein 70 (hsp70), putative Get druggable targets OG5_126588 All targets in OG5_126588
Echinococcus multilocularis heat shock protein 70 Get druggable targets OG5_126588 All targets in OG5_126588
Leishmania major DNA polymerase eta, putative Get druggable targets OG5_128521 All targets in OG5_128521
Loa Loa (eye worm) PLK/PLK1 protein kinase Get druggable targets OG5_127396 All targets in OG5_127396
Echinococcus granulosus heat shock protein 70 Get druggable targets OG5_126588 All targets in OG5_126588
Echinococcus granulosus heat shock protein 71 kDa protein Get druggable targets OG5_126588 All targets in OG5_126588
Giardia lamblia Ubiquitin carboxyl-terminal hydrolase 4 Get druggable targets OG5_127431 All targets in OG5_127431
Schistosoma japonicum Lethal(3)malignant brain tumor-like 3 protein, putative Get druggable targets OG5_130415 All targets in OG5_130415
Schistosoma japonicum ko:K09490 heat shock 70kDa protein 5, putative Get druggable targets OG5_126588 All targets in OG5_126588
Schistosoma japonicum ko:K03654 ATP-dependent DNA helicase RecQ, putative Get druggable targets OG5_126644 All targets in OG5_126644
Schistosoma japonicum expressed protein Get druggable targets OG5_130029 All targets in OG5_130029
Babesia bovis dnaK protein Get druggable targets OG5_126588 All targets in OG5_126588
Schistosoma mansoni DNA helicase recq5 Get druggable targets OG5_126644 All targets in OG5_126644
Plasmodium vivax thioredoxin reductase, putative Get druggable targets OG5_126785 All targets in OG5_126785
Plasmodium falciparum heat shock protein 70 Get druggable targets OG5_126588 All targets in OG5_126588
Trypanosoma brucei ubiquitin carboxyl-terminal hydrolase, putative Get druggable targets OG5_127431 All targets in OG5_127431
Schistosoma japonicum ko:K04380 microtubule-associated protein tau, putative Get druggable targets OG5_133504 All targets in OG5_133504
Echinococcus granulosus ubiquitin specific protease 41 Get druggable targets OG5_127431 All targets in OG5_127431
Echinococcus multilocularis Heat shock 70 kDa protein Get druggable targets OG5_126588 All targets in OG5_126588
Trichomonas vaginalis heat shock protein, putative Get druggable targets OG5_126588 All targets in OG5_126588
Schistosoma mansoni microtubule-associated protein tau Get druggable targets OG5_133504 All targets in OG5_133504
Echinococcus multilocularis heat shock protein 70 Get druggable targets OG5_126588 All targets in OG5_126588
Echinococcus granulosus Heat Shock protein family member hsp 3 Get druggable targets OG5_126588 All targets in OG5_126588
Leishmania braziliensis glucose-regulated protein 78, putative Get druggable targets OG5_126588 All targets in OG5_126588
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_127431 All targets in OG5_127431
Candida albicans DNA helicase Get druggable targets OG5_126644 All targets in OG5_126644
Trichomonas vaginalis CAMK family protein kinase Get druggable targets OG5_127396 All targets in OG5_127396
Trypanosoma brucei gambiense ATP-dependent DEAD/H DNA helicase recQ, putative Get druggable targets OG5_126644 All targets in OG5_126644
Echinococcus granulosus arachidonate 5 lipoxygenase Get druggable targets OG5_127482 All targets in OG5_127482
Plasmodium vivax glutathione reductase, putative Get druggable targets OG5_126785 All targets in OG5_126785
Brugia malayi acetyltransferase, GNAT family protein Get druggable targets OG5_127781 All targets in OG5_127781
Giardia lamblia Cytosolic HSP70 Get druggable targets OG5_126588 All targets in OG5_126588
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase Get druggable targets OG5_127431 All targets in OG5_127431
Echinococcus granulosus heat shock protein 70 Get druggable targets OG5_126588 All targets in OG5_126588
Entamoeba histolytica heat shock protein 70 family Get druggable targets OG5_126588 All targets in OG5_126588
Echinococcus multilocularis heat shock protein kDa heat shock kDa protein Get druggable targets OG5_126588 All targets in OG5_126588
Schistosoma japonicum expressed protein Get druggable targets OG5_127917 All targets in OG5_127917
Plasmodium berghei ATP-dependent DNA helicase Q1, putative Get druggable targets OG5_126644 All targets in OG5_126644
Trichomonas vaginalis CAMK family protein kinase Get druggable targets OG5_127396 All targets in OG5_127396
Echinococcus multilocularis thioredoxin glutathione reductase Get druggable targets OG5_126785 All targets in OG5_126785
Brugia malayi ATP-dependent DNA helicase, RecQ family protein Get druggable targets OG5_126644 All targets in OG5_126644
Schistosoma japonicum Ubiquitin carboxyl-terminal hydrolase 8, putative Get druggable targets OG5_127431 All targets in OG5_127431
Echinococcus granulosus heat shock kda protein Get druggable targets OG5_126588 All targets in OG5_126588
Babesia bovis ATP-dependent DNA helicase, RecQ family protein Get druggable targets OG5_126644 All targets in OG5_126644
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) Get druggable targets OG5_131088 All targets in OG5_131088
Leishmania braziliensis ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative Get druggable targets OG5_127431 All targets in OG5_127431
Candida albicans HSP70 Get druggable targets OG5_126588 All targets in OG5_126588
Plasmodium knowlesi heat shock protein 70, putative Get druggable targets OG5_126588 All targets in OG5_126588
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein Get druggable targets OG5_126644 All targets in OG5_126644
Plasmodium yoelii thioredoxin reductase Get druggable targets OG5_126785 All targets in OG5_126785
Echinococcus multilocularis Heat shock 70 kDa protein Get druggable targets OG5_126588 All targets in OG5_126588
Plasmodium falciparum thioredoxin reductase Get druggable targets OG5_126785 All targets in OG5_126785
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein Get druggable targets OG5_127431 All targets in OG5_127431
Trichomonas vaginalis DNA helicase recq, putative Get druggable targets OG5_126644 All targets in OG5_126644
Entamoeba histolytica heat shock protein 70, putative Get druggable targets OG5_126588 All targets in OG5_126588
Plasmodium falciparum glutathione reductase Get druggable targets OG5_126785 All targets in OG5_126785
Schistosoma japonicum similar to Heat shock 70 kDa protein cognate 4, putative Get druggable targets OG5_126588 All targets in OG5_126588
Trichomonas vaginalis heat shock protein, putative Get druggable targets OG5_126588 All targets in OG5_126588
Trypanosoma congolense luminal binding protein 1 (BiP), putative Get druggable targets OG5_126588 All targets in OG5_126588
Trichomonas vaginalis heat shock protein, putative Get druggable targets OG5_126588 All targets in OG5_126588
Leishmania mexicana heat-shock protein hsp70, putative Get druggable targets OG5_126588 All targets in OG5_126588
Echinococcus granulosus histone lysine N methyltransferase NSD3 Get druggable targets OG5_130029 All targets in OG5_130029
Neospora caninum Pc21g17280 protein, related Get druggable targets OG5_128521 All targets in OG5_128521
Schistosoma mansoni gcn5proteinral control of amino-acid synthesis 5-like 2 gcnl2 Get druggable targets OG5_127781 All targets in OG5_127781
Trichomonas vaginalis CAMK family protein kinase Get druggable targets OG5_127396 All targets in OG5_127396
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_126644 All targets in OG5_126644
Echinococcus multilocularis serine:threonine protein kinase PLK1 Get druggable targets OG5_127396 All targets in OG5_127396
Cryptosporidium parvum ubiquitin C-terminal hydrolase of the cysteine proteinase fold Get druggable targets OG5_127431 All targets in OG5_127431
Leishmania infantum glucose-regulated protein 78, putative Get druggable targets OG5_126588 All targets in OG5_126588
Trypanosoma cruzi ATP-dependent DEAD/H DNA helicase recQ, putative Get druggable targets OG5_126644 All targets in OG5_126644
Plasmodium falciparum histone acetyltransferase GCN5 Get druggable targets OG5_127781 All targets in OG5_127781
Echinococcus granulosus guanine nucleotide binding protein Gs subunit Get druggable targets OG5_131088 All targets in OG5_131088
Toxoplasma gondii heat shock protein HSP70 Get druggable targets OG5_126588 All targets in OG5_126588
Echinococcus granulosus ATP dependent DNA helicase Q5 Get druggable targets OG5_126644 All targets in OG5_126644
Schistosoma mansoni lipoxygenase Get druggable targets OG5_127482 All targets in OG5_127482
Echinococcus multilocularis heat shock protein 70 Get druggable targets OG5_126588 All targets in OG5_126588
Echinococcus multilocularis heat shock protein 70 Get druggable targets OG5_126588 All targets in OG5_126588
Schistosoma japonicum IPR000276,Rhodopsin-like GPCR superfamily,domain-containing Get druggable targets OG5_136011 All targets in OG5_136011
Leishmania donovani luminal binding protein 1 (BiP), putative Get druggable targets OG5_126588 All targets in OG5_126588
Leishmania mexicana protein kinase, putative,polo-like protein kinase, putative Get druggable targets OG5_127396 All targets in OG5_127396
Candida albicans similar to S. cerevisiae DNA polymerase pol-eta, involved in the bypass of distorted DNA lesions Get druggable targets OG5_128521 All targets in OG5_128521
Echinococcus multilocularis histone lysine N methyltransferase NSD3 Get druggable targets OG5_130029 All targets in OG5_130029
Plasmodium yoelii ATP-dependent DNA helicase recQ-related Get druggable targets OG5_126644 All targets in OG5_126644
Echinococcus multilocularis heat shock protein 70 Get druggable targets OG5_126588 All targets in OG5_126588
Trichomonas vaginalis heat shock protein, putative Get druggable targets OG5_126588 All targets in OG5_126588
Echinococcus granulosus histone acetyltransferase KAT2B Get druggable targets OG5_127781 All targets in OG5_127781
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) Get druggable targets OG5_131088 All targets in OG5_131088
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein Get druggable targets OG5_126644 All targets in OG5_126644
Leishmania infantum heat shock protein 70-related protein Get druggable targets OG5_126588 All targets in OG5_126588
Trichomonas vaginalis bromodomain-containing protein, putative Get druggable targets OG5_127781 All targets in OG5_127781
Echinococcus granulosus endonuclease exonuclease phosphatase Get druggable targets OG5_130415 All targets in OG5_130415
Trypanosoma brucei heat shock protein 70 Get druggable targets OG5_126588 All targets in OG5_126588
Trichomonas vaginalis DNA helicase recq, putative Get druggable targets OG5_126644 All targets in OG5_126644
Trypanosoma brucei trypanothione reductase Get druggable targets OG5_126785 All targets in OG5_126785
Echinococcus granulosus Heat shock 70 kDa protein 4 Get druggable targets OG5_126588 All targets in OG5_126588
Brugia malayi Helix-loop-helix DNA-binding domain containing protein Get druggable targets OG5_133408 All targets in OG5_133408
Candida albicans heat shock protein 70 Get druggable targets OG5_126588 All targets in OG5_126588
Schistosoma japonicum IPR001024,Lipoxygenase, LH2;IPR013819,Lipoxygenase, C-terminal,domain-containing Get druggable targets OG5_127482 All targets in OG5_127482
Brugia malayi ATP-dependent DNA helicase, RecQ family protein Get druggable targets OG5_126644 All targets in OG5_126644
Echinococcus multilocularis Heat shock 70 kDa protein Get druggable targets OG5_126588 All targets in OG5_126588
Entamoeba histolytica heat shock protein 70, putative Get druggable targets OG5_126588 All targets in OG5_126588
Plasmodium yoelii histone acetyltransferase GCN5-related Get druggable targets OG5_127781 All targets in OG5_127781
Schistosoma japonicum ko:K00384 thioredoxin reductase (NADPH) [EC1.8.1.9], putative Get druggable targets OG5_126785 All targets in OG5_126785
Echinococcus granulosus heat shock protein 70 Get druggable targets OG5_126588 All targets in OG5_126588
Echinococcus multilocularis heat shock kda protein Get druggable targets OG5_126588 All targets in OG5_126588
Echinococcus granulosus heat shock protein 70 Get druggable targets OG5_126588 All targets in OG5_126588
Candida albicans similar to S. cerevisiae KAR2 (YJL034W) HSP70/ BiP family ATPase and chaperone involved in translocation of nascent polypeptides Get druggable targets OG5_126588 All targets in OG5_126588
Schistosoma japonicum ko:K00461 arachidonate 5-lipoxygenase [EC1.13.11.34], putative Get druggable targets OG5_127482 All targets in OG5_127482
Candida albicans Cytoplasmic chaperone Get druggable targets OG5_126588 All targets in OG5_126588
Theileria parva DNA helicase, putative Get druggable targets OG5_126644 All targets in OG5_126644
Onchocerca volvulus Serine\/threonine kinase homolog Get druggable targets OG5_127396 All targets in OG5_127396
Candida albicans bromodomain protein similar to S. cerevisiae GCN5 (YGR252W) histone acetyltransferase Get druggable targets OG5_127781 All targets in OG5_127781
Plasmodium vivax heat shock 70 kDa protein, putative Get druggable targets OG5_126588 All targets in OG5_126588
Schistosoma mansoni lipoxygenase Get druggable targets OG5_127482 All targets in OG5_127482
Leishmania mexicana heat-shock protein hsp70, putative Get druggable targets OG5_126588 All targets in OG5_126588
Echinococcus multilocularis heat shock 70 kDa protein 1A:1B Get druggable targets OG5_126588 All targets in OG5_126588
Schistosoma mansoni hypothetical protein Get druggable targets OG5_130415 All targets in OG5_130415
Echinococcus multilocularis Heat shock 70 kDa protein Get druggable targets OG5_126588 All targets in OG5_126588
Brugia malayi jmjC domain containing protein Get druggable targets OG5_127917 All targets in OG5_127917
Plasmodium falciparum heat shock protein 70 Get druggable targets OG5_126588 All targets in OG5_126588
Echinococcus granulosus Heat shock 70 kDa protein Get druggable targets OG5_126588 All targets in OG5_126588
Schistosoma japonicum expressed protein Get druggable targets OG5_127917 All targets in OG5_127917
Neospora caninum Heat shock protein 70 (Precursor), related Get druggable targets OG5_126588 All targets in OG5_126588
Schistosoma japonicum ko:K03509 DNA polymerase eta subunit, putative Get druggable targets OG5_128521 All targets in OG5_128521
Schistosoma mansoni ubiquitin-specific peptidase 2 (C19 family) Get druggable targets OG5_127431 All targets in OG5_127431
Leishmania donovani heat-shock protein hsp70, putative Get druggable targets OG5_126588 All targets in OG5_126588
Schistosoma japonicum ko:K04632 guanine nucleotide binding protein (G protein), alpha stimulating, putative Get druggable targets OG5_131088 All targets in OG5_131088
Schistosoma japonicum IPR001394,Peptidase C19, ubiquitin carboxyl-terminal hydrolase 2,domain-containing Get druggable targets OG5_127431 All targets in OG5_127431
Candida albicans HSP70 Get druggable targets OG5_126588 All targets in OG5_126588
Trichomonas vaginalis CAMK family protein kinase Get druggable targets OG5_127396 All targets in OG5_127396
Cryptosporidium hominis DEAD/DEAH box helicase Get druggable targets OG5_126644 All targets in OG5_126644
Echinococcus granulosus heat shock protein Get druggable targets OG5_126588 All targets in OG5_126588
Plasmodium falciparum ADP-dependent DNA helicase RecQ Get druggable targets OG5_126644 All targets in OG5_126644
Echinococcus multilocularis ATP dependent DNA helicase Q1 Get druggable targets OG5_126644 All targets in OG5_126644
Echinococcus granulosus heat shock protein 70 Get druggable targets OG5_126588 All targets in OG5_126588
Trypanosoma congolense protein kinase, putative Get druggable targets OG5_127396 All targets in OG5_127396
Leishmania donovani ubiquitin carboxyl-terminal hydrolase, putative Get druggable targets OG5_127431 All targets in OG5_127431
Trypanosoma congolense trypanothione reductase, putative Get druggable targets OG5_126785 All targets in OG5_126785
Trichomonas vaginalis CAMK family protein kinase Get druggable targets OG5_127396 All targets in OG5_127396
Giardia lamblia Bip Get druggable targets OG5_126588 All targets in OG5_126588
Candida albicans heat shock protein Get druggable targets OG5_126588 All targets in OG5_126588
Plasmodium knowlesi glutathione reductase, putative Get druggable targets OG5_126785 All targets in OG5_126785
Leishmania major DNA polymerase eta, putative Get druggable targets OG5_128521 All targets in OG5_128521
Leishmania braziliensis heat-shock protein hsp70, putative Get druggable targets OG5_126588 All targets in OG5_126588
Echinococcus multilocularis heat shock protein 70b Get druggable targets OG5_126588 All targets in OG5_126588
Plasmodium knowlesi thioredoxin reductase, putative Get druggable targets OG5_126785 All targets in OG5_126785
Toxoplasma gondii chaperonin protein BiP Get druggable targets OG5_126588 All targets in OG5_126588
Entamoeba histolytica hypothetical protein Get druggable targets OG5_126588 All targets in OG5_126588
Trypanosoma brucei gambiense trypanothione reductase, putative Get druggable targets OG5_126785 All targets in OG5_126785
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase domain containing protein Get druggable targets OG5_127431 All targets in OG5_127431
Echinococcus multilocularis heat shock protein 70 Get druggable targets OG5_126588 All targets in OG5_126588
Toxoplasma gondii histone lysine acetyltransferase GCN5-A Get druggable targets OG5_127781 All targets in OG5_127781
Theileria parva hypothetical protein Get druggable targets OG5_126644 All targets in OG5_126644
Echinococcus granulosus heat shock protein 70 Get druggable targets OG5_126588 All targets in OG5_126588
Candida albicans protein serine/threonine kinase Get druggable targets OG5_127396 All targets in OG5_127396
Echinococcus granulosus heat shock protein 70 Get druggable targets OG5_126588 All targets in OG5_126588
Echinococcus multilocularis microtubule associated protein 2 Get druggable targets OG5_133504 All targets in OG5_133504
Echinococcus multilocularis heat shock 70 kda protein 1a Get druggable targets OG5_126588 All targets in OG5_126588
Candida albicans Cytoplasmic chaperone Get druggable targets OG5_126588 All targets in OG5_126588
Echinococcus granulosus heat shock protein 70 Get druggable targets OG5_126588 All targets in OG5_126588
Echinococcus multilocularis heat shock protein 70 Get druggable targets OG5_126588 All targets in OG5_126588
Leishmania braziliensis heat shock protein 70-related protein Get druggable targets OG5_126588 All targets in OG5_126588
Echinococcus granulosus ATP dependent DNA helicase Q1 Get druggable targets OG5_126644 All targets in OG5_126644
Echinococcus granulosus guanine nucleotide binding protein Gs subunit Get druggable targets OG5_131088 All targets in OG5_131088
Echinococcus multilocularis gcn5proteinral control of amino acid synthesis Get druggable targets OG5_127781 All targets in OG5_127781
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_128521 All targets in OG5_128521
Candida albicans DNA helicase Get druggable targets OG5_126644 All targets in OG5_126644
Entamoeba histolytica recQ family helicase, putative Get druggable targets OG5_126644 All targets in OG5_126644
Leishmania donovani ATP-dependent DEAD/H DNA helicase recQ, putative Get druggable targets OG5_126644 All targets in OG5_126644
Trichomonas vaginalis conserved hypothetical protein Get druggable targets OG5_127431 All targets in OG5_127431
Plasmodium falciparum heat shock protein 70 Get druggable targets OG5_126588 All targets in OG5_126588
Plasmodium yoelii hypothetical protein Get druggable targets OG5_127917 All targets in OG5_127917
Trypanosoma congolense DNA polymerase eta, putative Get druggable targets OG5_128521 All targets in OG5_128521
Cryptosporidium parvum heat shock protein, Hsp70 Get druggable targets OG5_126588 All targets in OG5_126588
Echinococcus granulosus heat shock protein 70 Get druggable targets OG5_126588 All targets in OG5_126588
Trichomonas vaginalis heat shock protein, putative Get druggable targets OG5_126588 All targets in OG5_126588
Plasmodium vivax histone acetyltransferase GCN5, putative Get druggable targets OG5_127781 All targets in OG5_127781
Echinococcus multilocularis Transcription factor, JmjC domain containing protein Get druggable targets OG5_127917 All targets in OG5_127917
Candida albicans protein serine/threonine kinase Get druggable targets OG5_127396 All targets in OG5_127396
Trichomonas vaginalis heat shock protein 70kD, putative Get druggable targets OG5_126588 All targets in OG5_126588
Leishmania major heat-shock protein hsp70, putative Get druggable targets OG5_126588 All targets in OG5_126588
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit Get druggable targets OG5_131088 All targets in OG5_131088
Schistosoma japonicum ko:K05302 histone-lysine N-methyltransferase [EC2.1.1.43], putative Get druggable targets OG5_130029 All targets in OG5_130029
Brugia malayi heat shock 70 kDa protein C precursor Get druggable targets OG5_126588 All targets in OG5_126588
Leishmania braziliensis DNA polymerase eta, putative Get druggable targets OG5_128521 All targets in OG5_128521
Echinococcus granulosus Peptidase C19 ubiquitin carboxyl terminal hydrolase 2 Get druggable targets OG5_127431 All targets in OG5_127431
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_126588 All targets in OG5_126588
Schistosoma japonicum Ubiquitin carboxyl-terminal hydrolase 8, putative Get druggable targets OG5_127431 All targets in OG5_127431
Cryptosporidium hominis histone acetyltransferase Get druggable targets OG5_127781 All targets in OG5_127781
Entamoeba histolytica heat shock protein 70, putative Get druggable targets OG5_126588 All targets in OG5_126588
Echinococcus granulosus heat shock protein kDa Get druggable targets OG5_126588 All targets in OG5_126588
Trichomonas vaginalis DNA helicase recq1, putative Get druggable targets OG5_126644 All targets in OG5_126644
Echinococcus multilocularis heat shock protein 71 kDa protein Get druggable targets OG5_126588 All targets in OG5_126588
Leishmania mexicana glucose-regulated protein 78, putative Get druggable targets OG5_126588 All targets in OG5_126588
Treponema pallidum ATP-dependent DNA helicase Get druggable targets OG5_126644 All targets in OG5_126644
Cryptosporidium parvum RecQ bloom helicase (RNA helicase+hrdc) Get druggable targets OG5_126644 All targets in OG5_126644
Plasmodium berghei glutathione reductase, putative Get druggable targets OG5_126785 All targets in OG5_126785
Trypanosoma brucei gambiense glucose-regulated protein 78, putative,luminal binding protein 1 (BiP), putative Get druggable targets OG5_126588 All targets in OG5_126588
Candida albicans similar to S. cerevisiae GLR1 (YPL091W) glutathione oxidoreductase Get druggable targets OG5_126785 All targets in OG5_126785
Echinococcus granulosus neuropeptide receptor A26 Get druggable targets OG5_136011 All targets in OG5_136011
Leishmania mexicana ATP-dependent DEAD/H DNA helicase recQ, putative Get druggable targets OG5_126644 All targets in OG5_126644
Schistosoma mansoni DNA polymerase eta Get druggable targets OG5_128521 All targets in OG5_128521
Leishmania infantum ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative Get druggable targets OG5_127431 All targets in OG5_127431
Toxoplasma gondii histone lysine acetyltransferase GCN5-B Get druggable targets OG5_127781 All targets in OG5_127781
Theileria parva thioredoxin reductase, putative Get druggable targets OG5_126785 All targets in OG5_126785
Entamoeba histolytica heat shock protein70, hsp70A2, putative Get druggable targets OG5_126588 All targets in OG5_126588
Trypanosoma brucei gambiense DNA polymerase eta, putative Get druggable targets OG5_128521 All targets in OG5_128521
Schistosoma japonicum IPR015063,Domain of unknown function DUF1873,domain-containing Get druggable targets OG5_127431 All targets in OG5_127431
Leishmania infantum DNA polymerase eta, putative Get druggable targets OG5_128521 All targets in OG5_128521
Leishmania mexicana Get druggable targets OG5_128521 All targets in OG5_128521
Trichomonas vaginalis CAMK family protein kinase Get druggable targets OG5_127396 All targets in OG5_127396
Schistosoma mansoni heat shock protein 70 Get druggable targets OG5_126588 All targets in OG5_126588
Schistosoma japonicum Serine/threonine-protein kinase PLK1, putative Get druggable targets OG5_127396 All targets in OG5_127396
Echinococcus granulosus transcription factor eb Get druggable targets OG5_133408 All targets in OG5_133408
Echinococcus multilocularis heat shock 70 kDa protein 1 Get druggable targets OG5_126588 All targets in OG5_126588
Cryptosporidium parvum thioredoxin reductase 1 Get druggable targets OG5_126785 All targets in OG5_126785
Echinococcus multilocularis bloom syndrome protein Get druggable targets OG5_126644 All targets in OG5_126644
Trypanosoma cruzi heat shock protein 70 (hsp70), putative Get druggable targets OG5_126588 All targets in OG5_126588
Echinococcus multilocularis Get druggable targets OG5_126588 All targets in OG5_126588
Schistosoma mansoni ubiquitin-specific peptidase 8 (C19 family) Get druggable targets OG5_127431 All targets in OG5_127431
Babesia bovis histone acetyltransferase Get druggable targets OG5_127781 All targets in OG5_127781
Echinococcus granulosus heat shock protein 70 Get druggable targets OG5_126588 All targets in OG5_126588
Schistosoma mansoni DNA helicase recq1 Get druggable targets OG5_126644 All targets in OG5_126644
Echinococcus multilocularis heat shock protein kDa heat shock kDa protein Get druggable targets OG5_126588 All targets in OG5_126588
Mycobacterium tuberculosis NADPH-dependent mycothiol reductase Mtr Get druggable targets OG5_126785 All targets in OG5_126785
Echinococcus granulosus heat shock protein 70 Get druggable targets OG5_126588 All targets in OG5_126588
Echinococcus multilocularis heat shock protein 70 Get druggable targets OG5_126588 All targets in OG5_126588
Trypanosoma congolense heat shock 70 kDa protein, putative Get druggable targets OG5_126588 All targets in OG5_126588
Trypanosoma brucei luminal binding protein 1 (BiP), putative Get druggable targets OG5_126588 All targets in OG5_126588
Echinococcus multilocularis Heat shock 70 kDa protein 4 Get druggable targets OG5_126588 All targets in OG5_126588
Leishmania mexicana heat shock protein 70-related protein Get druggable targets OG5_126588 All targets in OG5_126588
Trypanosoma congolense luminal binding protein 1 (BiP), putative Get druggable targets OG5_126588 All targets in OG5_126588
Candida albicans one of two closely related potential jumonji-like transcription factor genes similar to S. cerevisiae RPH1 (YER169W) damage-resp Get druggable targets OG5_127917 All targets in OG5_127917
Echinococcus granulosus Heat shock 70 kDa protein 4 Get druggable targets OG5_126588 All targets in OG5_126588
Trichomonas vaginalis heat shock protein, putative Get druggable targets OG5_126588 All targets in OG5_126588
Plasmodium berghei heat shock protein 70, putative Get druggable targets OG5_126588 All targets in OG5_126588
Schistosoma japonicum hypothetical protein Get druggable targets OG5_126588 All targets in OG5_126588
Cryptosporidium hominis ubiquitin specific protease 66 Get druggable targets OG5_127431 All targets in OG5_127431
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative Get druggable targets OG5_127431 All targets in OG5_127431
Cryptosporidium parvum GCN5 like acetylase + bromodomain Get druggable targets OG5_127781 All targets in OG5_127781
Echinococcus multilocularis heat shock protein 70 Get druggable targets OG5_126588 All targets in OG5_126588
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain Get druggable targets OG5_131088 All targets in OG5_131088
Echinococcus granulosus dna polymerase eta Get druggable targets OG5_128521 All targets in OG5_128521
Trypanosoma brucei ATP-dependent DEAD/H DNA helicase recQ, putative Get druggable targets OG5_126644 All targets in OG5_126644
Babesia bovis ATP-dependent DNA helicase, RecQ family protein Get druggable targets OG5_126644 All targets in OG5_126644
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 8 Get druggable targets OG5_127431 All targets in OG5_127431
Echinococcus granulosus heat shock protein 70 Get druggable targets OG5_126588 All targets in OG5_126588
Echinococcus multilocularis heat shock protein 70 related Get druggable targets OG5_126588 All targets in OG5_126588
Neospora caninum hypothetical protein Get druggable targets OG5_127781 All targets in OG5_127781
Echinococcus multilocularis heat shock protein 70 Get druggable targets OG5_126588 All targets in OG5_126588
Loa Loa (eye worm) jmjC domain-containing protein Get druggable targets OG5_127917 All targets in OG5_127917
Echinococcus multilocularis heat shock protein 70 Get druggable targets OG5_126588 All targets in OG5_126588
Entamoeba histolytica acetyltransferase, GNAT family Get druggable targets OG5_127781 All targets in OG5_127781
Echinococcus multilocularis Heat Shock protein family member (hsp 3) Get druggable targets OG5_126588 All targets in OG5_126588
Echinococcus granulosus neuropeptide s receptor Get druggable targets OG5_136011 All targets in OG5_136011
Echinococcus granulosus Heat shock 70 kDa protein Get druggable targets OG5_126588 All targets in OG5_126588
Schistosoma mansoni heat shock protein 70 Get druggable targets OG5_126588 All targets in OG5_126588
Trypanosoma congolense heat shock 70 kDa protein, putative Get druggable targets OG5_126588 All targets in OG5_126588
Schistosoma japonicum ko:K01072 ubiquitin thiolesterase [EC3.1.2.15], putative Get druggable targets OG5_127431 All targets in OG5_127431
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_126644 All targets in OG5_126644
Trichomonas vaginalis heat shock protein, putative Get druggable targets OG5_126588 All targets in OG5_126588
Trichomonas vaginalis heat shock protein 70kD, putative Get druggable targets OG5_126588 All targets in OG5_126588
Trypanosoma cruzi DNA polymerase eta, putative Get druggable targets OG5_128521 All targets in OG5_128521
Trypanosoma brucei gambiense ubiquitin carboxyl-terminal hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative Get druggable targets OG5_127431 All targets in OG5_127431
Schistosoma japonicum JmjC domain-containing histone demethylation protein 3C, putative Get druggable targets OG5_127917 All targets in OG5_127917
Trypanosoma brucei polo-like protein kinase Get druggable targets OG5_127396 All targets in OG5_127396
Neospora caninum Glutathione reductase, related Get druggable targets OG5_126785 All targets in OG5_126785
Neospora caninum hypothetical protein Get druggable targets OG5_126644 All targets in OG5_126644
Schistosoma japonicum similar to Heat shock 70 kDa protein homolog, putative Get druggable targets OG5_126588 All targets in OG5_126588
Schistosoma japonicum Bloom syndrome protein homolog, putative Get druggable targets OG5_126644 All targets in OG5_126644
Trypanosoma cruzi ATP-dependent DEAD/H DNA helicase recQ, putative Get druggable targets OG5_126644 All targets in OG5_126644
Schistosoma japonicum ko:K06062 p300/CBP-associated factor, putative Get druggable targets OG5_127781 All targets in OG5_127781
Cryptosporidium parvum heat shock 70 (HSP70) protein Get druggable targets OG5_126588 All targets in OG5_126588
Loa Loa (eye worm) helix-loop-helix DNA-binding domain-containing protein Get druggable targets OG5_133408 All targets in OG5_133408
Echinococcus granulosus histone acetyltransferase KAT2B Get druggable targets OG5_127781 All targets in OG5_127781
Trypanosoma brucei heat shock 70 kDa protein, putative Get druggable targets OG5_126588 All targets in OG5_126588
Leishmania major ATP-dependent DEAD/H DNA helicase recQ, putative Get druggable targets OG5_126644 All targets in OG5_126644
Trichomonas vaginalis CAMK family protein kinase Get druggable targets OG5_127396 All targets in OG5_127396
Trypanosoma cruzi polo-like protein kinase, putative Get druggable targets OG5_127396 All targets in OG5_127396
Leishmania infantum heat-shock protein hsp70, putative Get druggable targets OG5_126588 All targets in OG5_126588
Brugia malayi heat shock 70 kDa protein Get druggable targets OG5_126588 All targets in OG5_126588
Echinococcus multilocularis heat shock protein 70 Get druggable targets OG5_126588 All targets in OG5_126588
Giardia lamblia Sgs1 DNA helicase, putative Get druggable targets OG5_126644 All targets in OG5_126644
Trichomonas vaginalis microsomal stress 70 protein ATPase core precursor, putative Get druggable targets OG5_126588 All targets in OG5_126588
Trypanosoma congolense heat shock 70 kDa protein, putative Get druggable targets OG5_126588 All targets in OG5_126588
Loa Loa (eye worm) RecQ helicase Get druggable targets OG5_126644 All targets in OG5_126644
Trichomonas vaginalis heat shock protein 70 (HSP70)-4, putative Get druggable targets OG5_126588 All targets in OG5_126588
Echinococcus multilocularis heat shock protein 70 Get druggable targets OG5_126588 All targets in OG5_126588
Echinococcus granulosus heat shock protein 70 Get druggable targets OG5_126588 All targets in OG5_126588
Trypanosoma brucei DNA polymerase eta, putative Get druggable targets OG5_128521 All targets in OG5_128521
Plasmodium vivax heat shock protein 70, putative Get druggable targets OG5_126588 All targets in OG5_126588
Schistosoma japonicum Probable JmjC domain-containing histone demethylation protein 3B, putative Get druggable targets OG5_127917 All targets in OG5_127917
Echinococcus granulosus serine:threonine protein kinase PLK1 Get druggable targets OG5_127396 All targets in OG5_127396
Echinococcus multilocularis Heat shock 70 kDa protein 4 Get druggable targets OG5_126588 All targets in OG5_126588
Echinococcus multilocularis heat shock protein 70 Get druggable targets OG5_126588 All targets in OG5_126588
Echinococcus multilocularis Heat shock 70 kDa protein Get druggable targets OG5_126588 All targets in OG5_126588
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase Get druggable targets OG5_127431 All targets in OG5_127431
Echinococcus granulosus bloom syndrome protein Get druggable targets OG5_126644 All targets in OG5_126644
Leishmania infantum heat-shock protein hsp70, putative Get druggable targets OG5_126588 All targets in OG5_126588
Leishmania infantum heat-shock protein hsp70, putative Get druggable targets OG5_126588 All targets in OG5_126588
Plasmodium knowlesi ATP-dependent DNA helicase Q1, putative Get druggable targets OG5_126644 All targets in OG5_126644
By sequence similarity to non orthologous known druggable targets
Species Potential target Known druggable target Length Alignment span Identity
Plasmodium berghei dihydrolipoyl dehydrogenase, apicoplast, putative Thioredoxin glutathione reductase   598 aa 538 aa 25.3 %
Plasmodium knowlesi dihydrolipoyl dehydrogenase, apicoplast, putative Thioredoxin glutathione reductase   598 aa 518 aa 22.0 %
Schistosoma mansoni GTP-binding protein alpha subunit gna GNAS complex locus 394 aa 450 aa 28.7 %
Brugia malayi Hypothetical 65.5 kDa Trp-Asp repeats containing protein F02E8.5 inchromosome X geminin, DNA replication inhibitor 209 aa 176 aa 27.8 %
Neospora caninum hypothetical protein Thioredoxin glutathione reductase   598 aa 485 aa 30.5 %
Plasmodium yoelii dihydrolipoamide dehydrogenase Thioredoxin glutathione reductase   598 aa 537 aa 24.2 %
Neospora caninum Dihydrolipoyl dehydrogenase (EC 1.8.1.4), related Thioredoxin glutathione reductase   598 aa 512 aa 28.3 %
Toxoplasma gondii NADPH-glutathione reductase Thioredoxin glutathione reductase   598 aa 555 aa 33.5 %
Plasmodium falciparum dihydrolipoyl dehydrogenase, apicoplast Thioredoxin glutathione reductase   598 aa 513 aa 25.0 %
Neospora caninum glutathione reductase, putative Thioredoxin glutathione reductase   598 aa 532 aa 34.6 %
Plasmodium falciparum heat shock protein 70 heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) 654 aa 613 aa 51.9 %
Plasmodium vivax dihydrolipoyl dehydrogenase, apicoplast, putative Thioredoxin glutathione reductase   598 aa 521 aa 21.5 %
Onchocerca volvulus Thioredoxin glutathione reductase   598 aa 533 aa 50.8 %
Plasmodium falciparum ubiquitin specific protease, putative ubiquitin specific peptidase 2 362 aa 378 aa 25.7 %
Giardia lamblia U5 small nuclear ribonucleoprotein 200 kDa helicase, putative RecQ helicase-like 649 aa 521 aa 19.8 %
Loa Loa (eye worm) pigment dispersing factor receptor c glucagon-like peptide 1 receptor 463 aa 388 aa 25.8 %
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Loa Loa (eye worm) hypothetical protein 0.0014 0.0008 0.0008
Brugia malayi Latrophilin receptor protein 2 0.0019 0.0026 0.0057
Echinococcus multilocularis MAM 0.0019 0.0028 0.0028
Echinococcus granulosus Jumonji AT rich interactive domain 1B 0.0013 0.0006 0.0006
Loa Loa (eye worm) hypothetical protein 0.006 0.017 0.017
Trypanosoma brucei dihydrolipoyl dehydrogenase 0.0016 0.0015 0.0306
Schistosoma mansoni serine/threonine protein kinase 0.0058 0.0163 0.0163
Trypanosoma brucei hypothetical protein, conserved 0.002 0.0029 0.0592
Trypanosoma cruzi DNA polymerase kappa, putative 0.0096 0.0295 0.5975
Echinococcus granulosus protein kinase c iota type 0.0016 0.0015 0.0015
Mycobacterium tuberculosis Possible DNA-damage-inducible protein P DinP (DNA polymerase V) (pol IV 2) (DNA nucleotidyltransferase (DNA-directed)) 0.0072 0.0211 0.2639
Echinococcus multilocularis dna polymerase eta 0.0095 0.029 0.029
Toxoplasma gondii 'chromo' (CHRromatin Organization MOdifier) domain-containing protein 0.0014 0.0008 0.0161
Onchocerca volvulus 0.0018 0.0023 0.0186
Onchocerca volvulus 0.0024 0.0043 0.0348
Echinococcus multilocularis Peptidase M1, membrane alanine aminopeptidase, N terminal 0.0153 0.0493 0.0493
Brugia malayi Disco-interacting protein 2 homolog 0.0047 0.0122 0.0266
Echinococcus multilocularis disco interacting protein 2 0.0047 0.0122 0.0122
Plasmodium vivax glutathione reductase, putative 0.0046 0.0119 0.2296
Mycobacterium tuberculosis Probable lipase LipD 0.0036 0.0085 0.0939
Schistosoma mansoni blooms syndrome DNA helicase 0.0024 0.0043 0.0043
Echinococcus multilocularis polycomb protein SCMH1 0.0058 0.016 0.016
Schistosoma mansoni ubiquitin-specific peptidase 2 (C19 family) 0.0048 0.0126 0.0126
Echinococcus granulosus RNA directed DNA polymerase 0.0041 0.0104 0.0104
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0092 0.0281 0.0281
Loa Loa (eye worm) heterochromatin protein 1 0.0084 0.0253 0.0253
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0019 0.0026 0.0026
Loa Loa (eye worm) hypothetical protein 0.0024 0.0043 0.0043
Entamoeba histolytica acetyltransferase, GNAT family 0.0047 0.0124 0.2517
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0019 0.0026 0.0057
Loa Loa (eye worm) hypothetical protein 0.0052 0.0141 0.0141
Echinococcus multilocularis atpase aaa+ type core atpase aaa type core 0.0979 0.3368 0.3368
Brugia malayi Doublecortin family protein 0.0024 0.0043 0.0094
Trichomonas vaginalis conserved hypothetical protein 0.0033 0.0076 0.1407
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0092 0.0281 0.0281
Loa Loa (eye worm) CXXC zinc finger family protein 0.0075 0.0222 0.0222
Echinococcus multilocularis bloom syndrome protein 0.0079 0.0234 0.0234
Brugia malayi ATP-dependent DNA helicase, RecQ family protein 0.0047 0.0122 0.0267
Echinococcus granulosus tyrosyl DNA phosphodiesterase 1 0.008 0.0237 0.0237
Trichomonas vaginalis Clan MA, family M1, aminopeptidase N-like metallopeptidase 0.0153 0.0493 1
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.0036 0.0085 0.0939
Echinococcus granulosus neuropeptide receptor 0.0114 0.0358 0.0358
Loa Loa (eye worm) AGC/PKC/ETA protein kinase 0.0017 0.0019 0.0019
Loa Loa (eye worm) hypothetical protein 0.0365 0.123 0.123
Schistosoma mansoni sex comb on midleg homolog 0.0058 0.016 0.016
Loa Loa (eye worm) DOMON domain-containing protein 0.0018 0.0023 0.0023
Echinococcus multilocularis dna polymerase kappa 0.0096 0.0295 0.0295
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0092 0.0281 0.0281
Echinococcus multilocularis peregrin 0.0051 0.0137 0.0137
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative 0.0023 0.0039 0.0791
Onchocerca volvulus 0.0036 0.0085 0.0689
Echinococcus granulosus dnaJ subfamily B 0.0494 0.1679 0.1679
Brugia malayi Cytochrome P450 family protein 0.0048 0.0125 0.0274
Giardia lamblia PHD finger protein 15 0.0035 0.0083 0.1968
Echinococcus multilocularis Chromobox protein 3 0.0014 0.0008 0.0008
Onchocerca volvulus 0.0153 0.0493 0.4011
Brugia malayi Valyl-tRNA synthetase 0.0014 0.0008 0.0017
Plasmodium falciparum ataxin-2 like protein, putative 0.0051 0.0138 0.2692
Schistosoma mansoni DNA polymerase eta 0.0095 0.029 0.029
Leishmania major DNA polymerase kappa, putative 0.0072 0.0211 0.4272
Echinococcus multilocularis dihydrolipoamide dehydrogenase 0.0016 0.0015 0.0015
Loa Loa (eye worm) hypothetical protein 0.0036 0.0085 0.0085
Brugia malayi Bloom's syndrome protein homolog 0.0079 0.0234 0.0511
Trichomonas vaginalis esterase, putative 0.0036 0.0085 0.1581
Mycobacterium tuberculosis NADPH-dependent mycothiol reductase Mtr 0.0046 0.0119 0.1401
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0022 0.0035 0.0563
Trichomonas vaginalis DNA helicase recq, putative 0.0053 0.0145 0.2825
Brugia malayi dihydrolipoyl dehydrogenase, mitochondrial precursor, putative 0.0016 0.0015 0.0033
Trypanosoma cruzi DNA polymerase eta, putative 0.0095 0.029 0.5879
Loa Loa (eye worm) MBCTL1 0.0066 0.0188 0.0188
Echinococcus multilocularis lipoxygenase domain containing protein 0.0024 0.0043 0.0043
Echinococcus granulosus dihydrolipoamide dehydrogenase 0.0016 0.0015 0.0015
Plasmodium falciparum heterochromatin protein 1 0.0014 0.0008 0.0011
Loa Loa (eye worm) hypothetical protein 0.0153 0.0493 0.0493
Echinococcus multilocularis geminin 0.0368 0.124 0.124
Brugia malayi Peptidase family M1 containing protein 0.0153 0.0493 0.1078
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0092 0.0281 0.0281
Toxoplasma gondii PHD-finger domain-containing protein 0.0012 0.0000052861 0.0001
Entamoeba histolytica DNA (cytosine-5)-methyltransferase, putative 0.0024 0.0043 0.0872
Trypanosoma cruzi hypothetical protein, conserved 0.002 0.0029 0.0592
Echinococcus multilocularis G protein coupled receptor 139 0.0114 0.0358 0.0358
Brugia malayi hypothetical protein 0.0033 0.0075 0.0164
Echinococcus multilocularis terminal deoxycytidyl transferase rev1 0.0064 0.0183 0.0183
Schistosoma mansoni aminopeptidase A (M01 family) 0.0153 0.0493 0.0493
Loa Loa (eye worm) hypothetical protein 0.006 0.017 0.017
Entamoeba histolytica chromodomain-helicase-DNA-binding protein, putative 0.0014 0.0008 0.0161
Schistosoma mansoni rab geranylgeranyl transferase alpha subunit 0.0064 0.0183 0.0183
Trypanosoma cruzi DNA damage repair protein, putative 0.002 0.0029 0.0592
Trichomonas vaginalis D-aminoacylase, putative 0.0036 0.0085 0.1581
Plasmodium vivax hypothetical protein, conserved 0.0014 0.0008 0.0011
Toxoplasma gondii aminopeptidase N, putative 0.0153 0.0493 1
Schistosoma mansoni microtubule-associated protein tau 0.0833 0.286 0.286
Trypanosoma cruzi ATP-dependent DEAD/H DNA helicase recQ, putative 0.0053 0.0145 0.2941
Brugia malayi ImpB/MucB/SamB family protein 0.0095 0.029 0.0634
Schistosoma mansoni chromodomain helicase DNA binding protein 0.0014 0.0008 0.0008
Loa Loa (eye worm) AGC/PKC/ALPHA protein kinase 0.0043 0.0111 0.0111
Mycobacterium tuberculosis Probable NADH dehydrogenase Ndh 0.0104 0.0323 0.4147
Schistosoma mansoni chromobox protein-related (chromobox 1) (heterochromatin 1) 0.0014 0.0008 0.0008
Echinococcus multilocularis aminopeptidase N 0.0153 0.0493 0.0493
Toxoplasma gondii thioredoxin reductase 0.0046 0.0119 0.2411
Echinococcus granulosus histone lysine N methyltransferase NSD3 0.004 0.01 0.01
Schistosoma mansoni tyrosyl-DNA phosphodiesterase 0.008 0.0237 0.0237
Trypanosoma brucei cytosine-specific DNA methylase, putative 0.0024 0.0043 0.0872
Entamoeba histolytica exodeoxyribonuclease III, putative 0.0023 0.0039 0.0791
Plasmodium vivax dihydrolipoyl dehydrogenase, apicoplast, putative 0.0016 0.0015 0.0158
Echinococcus granulosus MAM 0.0019 0.0028 0.0028
Trypanosoma brucei DNA polymerase kappa, putative 0.0052 0.0142 0.2869
Loa Loa (eye worm) hypothetical protein 0.0014 0.0008 0.0008
Echinococcus granulosus Protein kinase C brain isozyme 0.0058 0.0163 0.0163
Toxoplasma gondii ABC1 family protein 0.0036 0.0085 0.1717
Mycobacterium tuberculosis Probable reductase 0.0104 0.0323 0.4147
Brugia malayi Muscle positioning protein 4 0.0018 0.0023 0.005
Entamoeba histolytica serine/threonine protein kinase, putative 0.0114 0.0358 0.7249
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.0048 0.0128 0.2598
Echinococcus multilocularis chromodomain helicase DNA binding protein 1 0.0014 0.0008 0.0008
Trypanosoma cruzi hypothetical protein, conserved 0.002 0.0029 0.0592
Echinococcus multilocularis X box binding protein 1 0.0348 0.1171 0.1171
Entamoeba histolytica chromodomain-helicase-DNA-binding protein, putative 0.0014 0.0008 0.0161
Echinococcus multilocularis RUN 0.0024 0.0043 0.0043
Trypanosoma brucei hypothetical protein, conserved 0.0036 0.0085 0.1717
Plasmodium falciparum ADP-dependent DNA helicase RecQ 0.0072 0.0211 0.4183
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0092 0.0281 0.0281
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 8 0.0048 0.0126 0.0126
Echinococcus granulosus PHD finger protein rhinoceros 0.0035 0.0083 0.0083
Loa Loa (eye worm) glutathione reductase 0.0046 0.0119 0.0119
Plasmodium falciparum DNA (cytosine-5)-methyltransferase 0.0024 0.0043 0.0732
Loa Loa (eye worm) hypothetical protein 0.0018 0.0023 0.0023
Trypanosoma cruzi PAB1-binding protein , putative 0.0051 0.0138 0.2802
Echinococcus granulosus DNA methyltransferase 2, putative 0.0024 0.0043 0.0043
Echinococcus granulosus dna polymerase eta 0.0095 0.029 0.029
Schistosoma mansoni hypothetical protein 0.0018 0.0023 0.0023
Trypanosoma cruzi DNA polymerase kappa, putative 0.0096 0.0295 0.5975
Loa Loa (eye worm) doublecortin family protein 0.0024 0.0043 0.0043
Trypanosoma brucei DNA polymerase kappa, putative 0.0052 0.0142 0.2869
Echinococcus multilocularis dnaJ subfamily B 0.0494 0.1679 0.1679
Echinococcus granulosus chromobox protein 1 0.0084 0.0253 0.0253
Schistosoma mansoni SET domain protein 0.004 0.01 0.01
Schistosoma mansoni cpg binding protein 0.0077 0.0228 0.0228
Toxoplasma gondii histone lysine acetyltransferase GCN5-A 0.0051 0.0139 0.282
Trichomonas vaginalis chromobox protein, putative 0.0051 0.0137 0.265
Brugia malayi acetyltransferase, GNAT family protein 0.0175 0.0569 0.1244
Trichomonas vaginalis glutathione reductase, putative 0.0016 0.0015 0.0148
Brugia malayi Helix-loop-helix DNA-binding domain containing protein 0.013 0.0414 0.0904
Onchocerca volvulus 0.0019 0.0028 0.0225
Trypanosoma cruzi tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.008 0.0237 0.4812
Echinococcus multilocularis microtubule associated protein 2 0.0833 0.286 0.286
Echinococcus granulosus protein kinase C gamma type 0.0052 0.0141 0.0141
Leishmania major tyrosyl-DNA phosphodiesterase 1 0.008 0.0237 0.4812
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0092 0.0281 0.0281
Plasmodium vivax heterochromatin protein 1, putative 0.0014 0.0008 0.0011
Echinococcus granulosus chromobox protein 2 0.0014 0.0008 0.0008
Schistosoma mansoni hypothetical protein 0.0024 0.0043 0.0043
Echinococcus granulosus Ataxin 2 N terminaldomain containing protein 0.0023 0.004 0.004
Echinococcus multilocularis arachidonate 5 lipoxygenase 0.0142 0.0456 0.0456
Brugia malayi M-phase phosphoprotein, mpp8 0.0014 0.0008 0.0017
Brugia malayi F/Y-rich N-terminus family protein 0.0023 0.0042 0.0091
Echinococcus granulosus X box binding protein 1 0.0348 0.1171 0.1171
Mycobacterium tuberculosis Probable membrane NADH dehydrogenase NdhA 0.0104 0.0323 0.4147
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.0024 0.0043 0.0862
Schistosoma mansoni jumonji domain containing protein 0.0092 0.0279 0.0279
Brugia malayi hypothetical protein 0.0024 0.0043 0.0094
Echinococcus multilocularis ubiquitin specific protease 41 0.0048 0.0126 0.0126
Echinococcus granulosus Peptidase C19 ubiquitin carboxyl terminal hydrolase 2 0.0048 0.0126 0.0126
Brugia malayi hypothetical protein 0.1326 0.4576 1
Loa Loa (eye worm) cytochrome P450 family protein 0.0048 0.0125 0.0125
Leishmania major acetoin dehydrogenase e3 component-like protein 0.0016 0.0015 0.0306
Echinococcus multilocularis tyrosyl DNA phosphodiesterase 1 0.008 0.0237 0.0237
Trichomonas vaginalis chromobox protein, putative 0.0051 0.0137 0.265
Echinococcus multilocularis protein kinase c epsilon type 0.0017 0.0019 0.0019
Loa Loa (eye worm) hypothetical protein 0.0036 0.0085 0.0085
Echinococcus granulosus neuropeptide s receptor 0.0563 0.1918 0.1918
Echinococcus multilocularis SAM and MBT domain containing protein 0.0058 0.016 0.016
Loa Loa (eye worm) MH2 domain-containing protein 0.0144 0.0462 0.0462
Echinococcus granulosus RUN 0.0024 0.0043 0.0043
Schistosoma mansoni terminal deoxycytidyl transferase 0.0064 0.0183 0.0183
Loa Loa (eye worm) hypothetical protein 0.0048 0.0126 0.0126
Onchocerca volvulus 0.0365 0.123 1
Leishmania major ATP-dependent DEAD/H DNA helicase recQ, putative 0.0053 0.0145 0.2941
Onchocerca volvulus 0.0018 0.0023 0.0186
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0022 0.0035 0.0563
Toxoplasma gondii aldehyde dehydrogenase 0.0063 0.0179 0.3629
Schistosoma mansoni DNA (cytosine-5)-methyltransferase 0.0024 0.0043 0.0043
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.0023 0.0039 0.0039
Loa Loa (eye worm) helicase 0.0014 0.0008 0.0008
Schistosoma mansoni phd finger protein 0.0016 0.0015 0.0015
Loa Loa (eye worm) acetyltransferase 0.0175 0.0569 0.0569
Schistosoma mansoni hypothetical protein 0.0494 0.1679 0.1679
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0048 0.0126 0.2558
Trypanosoma brucei polo-like protein kinase 0.0114 0.0358 0.7249
Plasmodium falciparum ataxin-2 like protein, putative 0.0051 0.0138 0.2692
Schistosoma mansoni chromobox protein 0.0084 0.0253 0.0253
Trichomonas vaginalis penicillin-binding protein, putative 0.0036 0.0085 0.1581
Echinococcus multilocularis suppression of tumorigenicity 18 protein 0.0066 0.0188 0.0188
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0021 0.0035 0.0035
Trypanosoma cruzi hypothetical protein, conserved 0.0036 0.0085 0.1717
Trypanosoma brucei DNA polymerase kappa, putative 0.0096 0.0295 0.5975
Loa Loa (eye worm) hypothetical protein 0.0035 0.0083 0.0083
Mycobacterium tuberculosis Probable oxidoreductase 0.0116 0.0363 0.4693
Loa Loa (eye worm) hypothetical protein 0.0047 0.0122 0.0122
Schistosoma mansoni hypothetical protein 0.0019 0.0026 0.0026
Schistosoma mansoni ubiquitin-specific peptidase 8 (C19 family) 0.0048 0.0126 0.0126
Leishmania major hypothetical protein, conserved 0.0051 0.0138 0.2802
Schistosoma mansoni hypothetical protein 0.0019 0.0026 0.0026
Loa Loa (eye worm) ImpB/MucB/SamB family protein 0.0064 0.0183 0.0183
Echinococcus granulosus GPCR family 2 0.0019 0.0026 0.0026
Schistosoma mansoni cpg binding protein 0.0075 0.0222 0.0222
Leishmania major protein kinase, putative,polo-like protein kinase, putative 0.0114 0.0358 0.7249
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0014 0.0008 0.0000000013755
Schistosoma mansoni hypothetical protein 0.0019 0.0028 0.0028
Schistosoma mansoni chromobox protein 0.0014 0.0008 0.0008
Loa Loa (eye worm) helix-loop-helix DNA-binding domain-containing protein 0.013 0.0411 0.0411
Echinococcus granulosus chromodomain helicase DNA binding protein 4 0.0016 0.0015 0.0015
Echinococcus granulosus dna polymerase kappa 0.0096 0.0295 0.0295
Leishmania major apurinic/apyrimidinic endonuclease-redox protein 0.0023 0.0039 0.0791
Giardia lamblia DNA damage repair protein 0.002 0.0029 0.0413
Giardia lamblia DINP protein human, muc B family 0.0072 0.0211 0.5712
Trypanosoma cruzi Aminopeptidase M1, putative 0.0153 0.0493 1
Echinococcus multilocularis Jumonji, AT rich interactive domain 1B 0.0013 0.0006 0.0006
Trichomonas vaginalis CAMK family protein kinase 0.0114 0.0358 0.7204
Schistosoma mansoni hypothetical protein 0.0019 0.0026 0.0026
Plasmodium vivax hypothetical protein, conserved 0.0036 0.0085 0.159
Echinococcus granulosus lysine specific demethylase 5A 0.0045 0.0115 0.0115
Schistosoma mansoni aldehyde dehydrogenase 0.0063 0.0179 0.0179
Toxoplasma gondii histone lysine acetyltransferase GCN5-B 0.0051 0.0139 0.282
Schistosoma mansoni neuropeptide receptor 0.0114 0.0358 0.0358
Echinococcus multilocularis DNA methyltransferase 2, putative 0.0024 0.0043 0.0043
Mycobacterium tuberculosis Conserved hypothetical protein 0.0064 0.0183 0.2265
Echinococcus granulosus disco interacting protein 2 0.0047 0.0122 0.0122
Trypanosoma brucei DNA polymerase kappa, putative 0.0096 0.0295 0.5975
Echinococcus multilocularis neuropeptide s receptor 0.0563 0.1918 0.1918
Echinococcus multilocularis telomerase reverse transcriptase subunit 0.0041 0.0104 0.0104
Toxoplasma gondii ImpB/MucB/SamB family protein 0.0051 0.0136 0.2762
Echinococcus multilocularis lysine specific demethylase 5A 0.0043 0.0108 0.0108
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0022 0.0035 0.0563
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0019 0.0026 0.0026
Echinococcus granulosus puromycin sensitive aminopeptidase 0.0153 0.0493 0.0493
Trypanosoma brucei DNA polymerase kappa, putative 0.0096 0.0295 0.5975
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0014 0.0008 0.0000000013755
Chlamydia trachomatis dihydrolipoyl dehydrogenase 0.0016 0.0015 0.5
Trichomonas vaginalis CAMK family protein kinase 0.0114 0.0358 0.7204
Echinococcus multilocularis Chromo domain 0.0014 0.0008 0.0008
Brugia malayi hypothetical protein 0.0024 0.0043 0.0094
Leishmania major puromycin-sensitive aminopeptidase-like protein,metallo-peptidase, Clan MA(E), Family M1 0.0153 0.0493 1
Loa Loa (eye worm) thioredoxin reductase 0.0046 0.0119 0.0119
Schistosoma mansoni serine/threonine protein kinase 0.0114 0.0358 0.0358
Echinococcus granulosus bloom syndrome protein 0.0079 0.0234 0.0234
Trichomonas vaginalis CAMK family protein kinase 0.0114 0.0358 0.7204
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0016 0.0015 0.0306
Trichomonas vaginalis chromobox protein, putative 0.0084 0.0253 0.5044
Plasmodium falciparum dihydrolipoyl dehydrogenase, apicoplast 0.0016 0.0015 0.0158
Entamoeba histolytica tyrosyl-DNA phosphodiesterase, putative 0.008 0.0237 0.4812
Echinococcus multilocularis transcription factor Dp 1 0.0046 0.0121 0.0121
Loa Loa (eye worm) jmjC domain-containing protein 0.0073 0.0213 0.0213
Mycobacterium tuberculosis Probable conserved lipoprotein 0.0036 0.0085 0.0939
Trypanosoma brucei DNA polymerase kappa, putative 0.0052 0.0141 0.2857
Trypanosoma brucei Aminopeptidase M1, putative 0.0153 0.0493 1
Trypanosoma brucei chrX additional, unordered contigs 0.002 0.0029 0.0592
Onchocerca volvulus Heterochromatin protein 1 homolog 0.0051 0.0137 0.111
Loa Loa (eye worm) beta-lactamase 0.0036 0.0085 0.0085
Brugia malayi hypothetical protein 0.0014 0.0008 0.0017
Loa Loa (eye worm) tyrosyl-DNA phosphodiesterase 0.008 0.0237 0.0237
Schistosoma mansoni hypothetical protein 0.0355 0.1195 0.1195
Onchocerca volvulus 0.0075 0.0222 0.1801
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0048 0.0126 0.0276
Echinococcus granulosus Chromobox protein 3 0.0014 0.0008 0.0008
Giardia lamblia Sgs1 DNA helicase, putative 0.0047 0.0122 0.312
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0022 0.0035 0.0563
Trichomonas vaginalis cat eye syndrome critical region protein 2, cscr2, putative 0.0051 0.0139 0.2703
Loa Loa (eye worm) hypothetical protein 0.0095 0.029 0.029
Mycobacterium tuberculosis Probable aldehyde dehydrogenase 0.0063 0.0179 0.2211
Loa Loa (eye worm) hypothetical protein 0.0036 0.0085 0.0085
Loa Loa (eye worm) aminopeptidase N 0.0153 0.0493 0.0493
Loa Loa (eye worm) hypothetical protein 0.0037 0.0089 0.0089
Trypanosoma brucei DNA polymerase eta, putative 0.0095 0.029 0.5879
Schistosoma mansoni serine/threonine protein kinase 0.0058 0.0163 0.0163
Mycobacterium tuberculosis Conserved protein 0.0036 0.0085 0.0939
Schistosoma mansoni lipoxygenase 0.01 0.0307 0.0307
Leishmania major hypothetical protein, conserved 0.0036 0.0085 0.1717
Trichomonas vaginalis DNA polymerase IV / kappa, putative 0.0096 0.0295 0.5909
Loa Loa (eye worm) leukotriene A4 hydrolase 0.2885 1 1
Schistosoma mansoni hypothetical protein 0.0035 0.0083 0.0083
Echinococcus multilocularis histone lysine N methyltransferase NSD3 0.004 0.01 0.01
Mycobacterium ulcerans aldehyde dehydrogenase 0.0063 0.0179 0.3428
Plasmodium falciparum ATP-dependent DNA helicase Q1 0.0047 0.0122 0.2357
Giardia lamblia Ubiquitin carboxyl-terminal hydrolase 4 0.0048 0.0126 0.3243
Brugia malayi MH2 domain containing protein 0.0144 0.0462 0.1009
Entamoeba histolytica hypothetical protein 0.0014 0.0008 0.0161
Brugia malayi Thioredoxin reductase 0.0046 0.0119 0.026
Plasmodium vivax thioredoxin reductase, putative 0.0046 0.0119 0.2296
Giardia lamblia Histone acetyltransferase GCN5 0.0047 0.0124 0.3185
Onchocerca volvulus Alhambra homolog 0.0035 0.0083 0.0671
Schistosoma mansoni rab6-interacting 0.0024 0.0043 0.0043
Echinococcus multilocularis lipoxygenase domain containing protein 0.0024 0.0043 0.0043
Onchocerca volvulus 0.0018 0.0023 0.0186
Mycobacterium tuberculosis Possible penicillin-binding protein 0.0229 0.0757 1
Loa Loa (eye worm) hypothetical protein 0.0036 0.0085 0.0085
Leishmania major DNA polymerase kappa, putative,DNA polymerase IV, putative 0.0072 0.0211 0.4272
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.0023 0.0039 0.0039
Echinococcus multilocularis PHD finger protein rhinoceros 0.0035 0.0083 0.0083
Trypanosoma cruzi ATP-dependent DEAD/H DNA helicase recQ, putative 0.0024 0.0043 0.0862
Schistosoma mansoni rab6-interacting 0.0024 0.0043 0.0043
Brugia malayi Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain containing protein 0.0012 0 0.0001
Entamoeba histolytica recQ family helicase, putative 0.0053 0.0145 0.2941
Schistosoma mansoni hypothetical protein 0.0041 0.0103 0.0103
Mycobacterium ulcerans aldehyde dehydrogenase 0.0063 0.0179 0.3428
Plasmodium vivax ADP-dependent DNA helicase RecQ, putative 0.0049 0.0131 0.2549
Schistosoma mansoni chromobox protein 0.0014 0.0008 0.0008
Toxoplasma gondii 'chromo' (CHRromatin Organization MOdifier) domain-containing protein 0.0014 0.0008 0.0161
Entamoeba histolytica chromodomain-helicase-DNA-binding protein, putative 0.0014 0.0008 0.0161
Schistosoma mansoni hypothetical protein 0.0019 0.0026 0.0026
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0016 0.0015 0.0306
Brugia malayi alpha keto acid dehydrogenase complex, E3 component, lipoamide dehydrogenase 0.0012 0 0.0001
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.0023 0.0039 0.0791
Trypanosoma brucei PAB1-binding protein , putative 0.0051 0.0138 0.2802
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0048 0.0126 0.2436
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.0036 0.0085 0.1455
Entamoeba histolytica aminopeptidase, putative 0.0153 0.0493 1
Trypanosoma brucei DNA polymerase kappa, putative 0.0096 0.0295 0.5975
Loa Loa (eye worm) PLK/PLK1 protein kinase 0.0114 0.0358 0.0358
Onchocerca volvulus 0.0153 0.0493 0.4011
Echinococcus granulosus microtubule associated protein 2 0.0833 0.286 0.286
Trichomonas vaginalis CAMK family protein kinase 0.0114 0.0358 0.7204
Loa Loa (eye worm) hypothetical protein 0.0041 0.0103 0.0103
Mycobacterium tuberculosis Probable lipase LipE 0.0036 0.0085 0.0939
Loa Loa (eye worm) hypothetical protein 0.0019 0.0026 0.0026
Giardia lamblia Kinase, PLK 0.0114 0.0358 1
Echinococcus multilocularis aldehyde dehydrogenase, mitochondrial 0.0063 0.0179 0.0179
Brugia malayi C2-HC type zinc finger protein C.e-MyT1 0.0066 0.0188 0.0411
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0036 0.0085 0.0085
Schistosoma mansoni DNA helicase recq1 0.0047 0.0122 0.0122
Brugia malayi mbt repeat family protein 0.0058 0.016 0.0351
Trichomonas vaginalis CAMK family protein kinase 0.0057 0.0157 0.3075
Onchocerca volvulus 0.0024 0.0043 0.0348
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0048 0.0126 0.2436
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.0023 0.0039 0.0039
Trypanosoma cruzi DNA polymerase kappa, putative 0.0096 0.0295 0.5975
Echinococcus granulosus chromobox protein 1 0.0084 0.0253 0.0253
Trypanosoma brucei dihydrolipoamide dehydrogenase, point mutation 0.0016 0.0015 0.0306
Onchocerca volvulus Serine\/threonine kinase homolog 0.0114 0.0358 0.2908
Echinococcus granulosus beta LACTamase domain containing family member 0.0036 0.0085 0.0085
Loa Loa (eye worm) hypothetical protein 0.0014 0.0008 0.0008
Echinococcus granulosus jumonji domain containing protein 0.0049 0.0131 0.0131
Mycobacterium tuberculosis Probable hydrolase 0.0036 0.0085 0.0939
Schistosoma mansoni sex comb on midleg homolog 0.0058 0.016 0.016
Loa Loa (eye worm) hypothetical protein 0.0041 0.0104 0.0104
Echinococcus granulosus puromycin sensitive aminopeptidase 0.0153 0.0493 0.0493
Loa Loa (eye worm) hypothetical protein 0.0018 0.0023 0.0023
Wolbachia endosymbiont of Brugia malayi exonuclease III 0.0023 0.0039 1
Toxoplasma gondii WD domain, G-beta repeat-containing protein 0.0012 0.0000052861 0.0001
Trypanosoma cruzi ATP-dependent DEAD/H DNA helicase recQ, putative 0.0024 0.0043 0.0862
Brugia malayi polk-prov protein 0.0052 0.0141 0.0308
Schistosoma mansoni chromodomain helicase DNA binding protein 0.0016 0.0015 0.0015
Echinococcus multilocularis transcription factor eb 0.013 0.0414 0.0414
Echinococcus multilocularis leukotriene A 4 hydrolase 0.2885 1 1
Onchocerca volvulus 0.0036 0.0085 0.0689
Trypanosoma brucei DNA polymerase kappa, putative 0.0052 0.0142 0.2869
Trichomonas vaginalis DNA polymerase eta, putative 0.0096 0.0295 0.5909
Loa Loa (eye worm) hypothetical protein 0.0024 0.0043 0.0043
Brugia malayi PHD-finger family protein 0.0035 0.0083 0.018
Brugia malayi CXXC zinc finger family protein 0.0075 0.0222 0.0484
Echinococcus granulosus aldehyde dehydrogenase mitochondrial 0.0063 0.0179 0.0179
Echinococcus multilocularis ATP dependent DNA helicase Q1 0.0047 0.0122 0.0122
Onchocerca volvulus 0.0018 0.0023 0.0186
Plasmodium vivax histone acetyltransferase GCN5, putative 0.0051 0.0139 0.271
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0016 0.0015 0.0306
Toxoplasma gondii ImpB/MucB/SamB family protein 0.002 0.0029 0.0592
Loa Loa (eye worm) hypothetical protein 0.0013 0.0007 0.0007
Brugia malayi Protein kinase c protein 2 0.005 0.0133 0.029
Loa Loa (eye worm) hypothetical protein 0.0014 0.0008 0.0008
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.0047 0.0122 0.2472
Trypanosoma cruzi DNA polymerase eta, putative 0.0051 0.0136 0.2762
Trypanosoma brucei DNA polymerase kappa, putative 0.0096 0.0295 0.5975
Loa Loa (eye worm) hypothetical protein 0.0019 0.0028 0.0028
Trichomonas vaginalis Clan MA, family M1, aminopeptidase N-like metallopeptidase 0.0153 0.0493 1
Echinococcus granulosus transcription factor eb 0.013 0.0414 0.0414
Plasmodium vivax DNA (cytosine-5)-methyltransferase, putative 0.0024 0.0043 0.0732
Loa Loa (eye worm) transcription factor SMAD2 0.0144 0.0462 0.0462
Brugia malayi Peptidase family M1 containing protein 0.0153 0.0493 0.1078
Trichomonas vaginalis CAMK family protein kinase 0.0114 0.0358 0.7204
Echinococcus multilocularis puromycin sensitive aminopeptidase 0.0153 0.0493 0.0493
Echinococcus multilocularis cpg binding protein 0.0077 0.0228 0.0228
Onchocerca volvulus 0.0014 0.0008 0.0064
Toxoplasma gondii PHD-finger domain-containing protein 0.0035 0.0083 0.1673
Brugia malayi hypothetical protein 0.0051 0.0138 0.0302
Trypanosoma cruzi PAB1-binding protein , putative 0.0051 0.0138 0.2802
Schistosoma mansoni Tata binding protein associated factor (M01 family) 0.0153 0.0493 0.0493
Trypanosoma brucei PHD-zinc-finger like domain containing protein, putative 0.0012 0.0000052861 0.0001
Mycobacterium leprae DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE 0.0116 0.0363 1
Toxoplasma gondii chromodomain helicase DNA binding protein CHD1/SWI2/SNF2 0.0014 0.0008 0.0161
Schistosoma mansoni atypical protein kinase C 0.0016 0.0015 0.0015
Trypanosoma cruzi DNA damage repair protein, putative 0.002 0.0029 0.0592
Mycobacterium ulcerans exodeoxyribonuclease III protein XthA 0.0023 0.0039 0.0501
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0019 0.0026 0.0026
Brugia malayi Heterochromatin protein 1 0.0084 0.0253 0.0552
Echinococcus granulosus puromycin sensitive aminopeptidase 0.0153 0.0493 0.0493
Leishmania major DNA polymerase eta, putative 0.0095 0.029 0.5879
Echinococcus granulosus histone acetyltransferase KAT2B 0.017 0.0552 0.0552
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0022 0.0035 0.0563
Onchocerca volvulus Polycomb protein Sfmbt homolog 0.0058 0.016 0.1305
Echinococcus granulosus endonuclease exonuclease phosphatase 0.0232 0.0766 0.0766
Plasmodium falciparum thioredoxin reductase 0.0046 0.0119 0.2296
Echinococcus multilocularis chromobox protein 1 0.0084 0.0253 0.0253
Trypanosoma brucei DNA polymerase kappa, putative 0.0096 0.0295 0.5975
Trypanosoma cruzi metallo-peptidase, clan MA(E), family M1, putative 0.0153 0.0493 1
Echinococcus multilocularis protein kinase c iota type 0.0016 0.0015 0.0015
Trichomonas vaginalis mercuric reductase, putative 0.0016 0.0015 0.0148
Entamoeba histolytica hypothetical protein 0.0014 0.0008 0.0161
Echinococcus multilocularis puromycin sensitive aminopeptidase 0.0153 0.0493 0.0493
Brugia malayi ImpB/MucB/SamB family protein 0.0064 0.0183 0.04
Schistosoma mansoni hypothetical protein 0.0368 0.124 0.124
Echinococcus multilocularis Protein kinase C, brain isozyme 0.0058 0.0163 0.0163
Echinococcus multilocularis gcn5proteinral control of amino acid synthesis 0.0175 0.0569 0.0569
Trichomonas vaginalis chromobox protein, putative 0.0084 0.0253 0.5044
Trypanosoma cruzi DNA polymerase kappa, putative 0.0096 0.0295 0.5975
Loa Loa (eye worm) hypothetical protein 0.0014 0.0008 0.0008
Trypanosoma cruzi puromycin-sensitive aminopeptidase-like protein, putative 0.0153 0.0493 1
Loa Loa (eye worm) RecQ helicase 0.0079 0.0234 0.0234
Trypanosoma brucei unspecified product 0.0044 0.0114 0.2307
Loa Loa (eye worm) mbt repeat family protein 0.0058 0.016 0.016
Echinococcus multilocularis puromycin sensitive aminopeptidase 0.0153 0.0493 0.0493
Plasmodium vivax hypothetical protein, conserved 0.0035 0.0083 0.1546
Brugia malayi glutathione reductase 0.0046 0.0119 0.026
Schistosoma mansoni DNA helicase recq5 0.0047 0.0122 0.0122
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.0047 0.0122 0.2472
Brugia malayi hypothetical protein 0.0365 0.123 0.2688
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0092 0.0281 0.0615
Brugia malayi jmjC domain containing protein 0.0115 0.0361 0.079
Trypanosoma brucei unspecified product 0.0088 0.0267 0.5413
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0016 0.0015 0.0015
Trypanosoma brucei tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.008 0.0237 0.4812
Loa Loa (eye worm) hypothetical protein 0.0179 0.0582 0.0582
Echinococcus multilocularis histone acetyltransferase MYST2 0.0066 0.0188 0.0188
Schistosoma mansoni loxhd1 0.0024 0.0043 0.0043
Plasmodium falciparum LCCL domain-containing protein 0.0024 0.0043 0.073
Trypanosoma brucei DNA polymerase IV, putative 0.0096 0.0295 0.5975
Trypanosoma cruzi aminopeptidase, putative 0.0153 0.0493 1
Mycobacterium ulcerans aldehyde dehydrogenase 0.0063 0.0179 0.3428
Trypanosoma brucei ATP-dependent DEAD/H DNA helicase recQ, putative 0.0053 0.0145 0.2941
Brugia malayi serine/threonine-protein kinase plk-2 0.0114 0.0358 0.0782
Trichomonas vaginalis D-aminoacylase, putative 0.0036 0.0085 0.1581
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0016 0.0015 0.0306
Loa Loa (eye worm) hypothetical protein 0.0036 0.0085 0.0085
Brugia malayi hypothetical protein 0.0019 0.0028 0.006
Echinococcus granulosus aminopeptidase N 0.0153 0.0493 0.0493
Echinococcus granulosus suppression of tumorigenicity 18 protein 0.0066 0.0188 0.0188
Entamoeba histolytica deoxycytidyl transferase, putative 0.0064 0.0183 0.371
Echinococcus multilocularis Ataxin 2, N terminal,domain containing protein 0.0023 0.004 0.004
Schistosoma mansoni hypothetical protein 0.0019 0.0028 0.0028
Toxoplasma gondii NADPH-glutathione reductase 0.0016 0.0015 0.0306
Echinococcus multilocularis Transcription factor, JmjC domain containing protein 0.0115 0.0361 0.0361
Trichomonas vaginalis CAMK family protein kinase 0.0057 0.0157 0.3075
Toxoplasma gondii DNA methyltransferase 2, putative 0.0024 0.0043 0.0872
Onchocerca volvulus 0.0016 0.0015 0.0123
Schistosoma mansoni chromobox protein 0.0084 0.0253 0.0253
Leishmania major DNA damage repair protein, putative 0.002 0.0029 0.0592
Echinococcus multilocularis serine threonine protein kinase 0.0052 0.0141 0.0141
Echinococcus granulosus geminin 0.0368 0.124 0.124
Schistosoma mansoni kinase 0.0058 0.0162 0.0162
Onchocerca volvulus 0.0036 0.0085 0.0689
Schistosoma mansoni gcn5proteinral control of amino-acid synthesis 5-like 2 gcnl2 0.0175 0.0569 0.0569
Leishmania major aldehyde dehydrogenase, mitochondrial precursor 0.0063 0.0179 0.3629
Echinococcus granulosus lipoxygenase domain containing protein 0.0024 0.0043 0.0043
Plasmodium falciparum glutathione reductase 0.0016 0.0015 0.0158
Schistosoma mansoni dihydrolipoamide dehydrogenase 0.0016 0.0015 0.0015
Trypanosoma brucei aminopeptidase, putative 0.0153 0.0493 1
Toxoplasma gondii C-5 cytosine-specific DNA methylase superfamily protein 0.0024 0.0043 0.0872
Trichomonas vaginalis conserved hypothetical protein 0.0018 0.0023 0.0302
Trichomonas vaginalis CAMK family protein kinase 0.0114 0.0358 0.7204
Schistosoma mansoni hypothetical protein 0.0023 0.004 0.004
Schistosoma mansoni hypothetical protein 0.0014 0.0008 0.0008
Echinococcus multilocularis jumonji domain containing protein 0.0049 0.0131 0.0131
Trichomonas vaginalis DNA helicase recq, putative 0.0079 0.0234 0.4654
Loa Loa (eye worm) TK/ALK protein kinase 0.0019 0.0028 0.0028
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0016 0.0015 0.0306
Brugia malayi Tyrosyl-DNA phosphodiesterase family protein 0.008 0.0237 0.0519
Schistosoma mansoni bromodomain-containing nuclear protein 1 brd1 0.0035 0.0083 0.0083
Echinococcus granulosus histone acetyltransferase MYST2 0.0066 0.0188 0.0188
Echinococcus multilocularis Polycystic kidney disease protein 0.0024 0.0043 0.0043
Loa Loa (eye worm) PHD-finger family protein 0.0035 0.0083 0.0083
Brugia malayi Type III restriction enzyme, res subunit family protein 0.0014 0.0008 0.0017
Mycobacterium ulcerans aminopeptidase N PepN 0.0153 0.0493 1
Plasmodium falciparum AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0023 0.0039 0.0651
Mycobacterium tuberculosis Conserved protein 0.0036 0.0085 0.0939
Echinococcus granulosus histone acetyltransferase KAT2B 0.0051 0.0139 0.0139
Toxoplasma gondii BRCA1 C Terminus (BRCT) domain-containing protein 0.0028 0.0057 0.1154
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0016 0.0015 0.0306
Loa Loa (eye worm) CHromoDomain protein family member 0.0016 0.0015 0.0015
Brugia malayi Associated with TFs and helicases family protein 0.0014 0.0008 0.0017
Entamoeba histolytica recQ family DNA helicase 0.0024 0.0043 0.0862
Plasmodium falciparum histone acetyltransferase GCN5 0.0047 0.0124 0.2403
Schistosoma mansoni leukotriene A4 hydrolase (M01 family) 0.2885 1 1
Leishmania major trypanothione reductase 0.0046 0.0119 0.2411
Onchocerca volvulus 0.0018 0.0023 0.0186
Schistosoma mansoni hypothetical protein 0.0368 0.124 0.124
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0016 0.0015 0.0306
Treponema pallidum ATP-dependent DNA helicase 0.0024 0.0043 1
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0048 0.0126 0.2558
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0036 0.0085 0.0085
Brugia malayi beta-lactamase family protein 0.0036 0.0085 0.0185
Echinococcus multilocularis serine:threonine protein kinase PLK1 0.0114 0.0358 0.0358
Brugia malayi hypothetical protein 0.0153 0.0493 0.1078
Echinococcus multilocularis Peptidase C19, ubiquitin carboxyl terminal hydrolase 2 0.0048 0.0126 0.0126
Loa Loa (eye worm) hypothetical protein 0.0058 0.016 0.016
Brugia malayi hypothetical protein 0.0153 0.0493 0.1078
Schistosoma mansoni ap endonuclease 0.0023 0.0039 0.0039
Echinococcus granulosus cpg binding protein 0.0077 0.0228 0.0228
Plasmodium vivax ataxin-2 like protein, putative 0.0051 0.0138 0.2692
Toxoplasma gondii PHD-finger domain-containing protein 0.0035 0.0083 0.1673
Trypanosoma cruzi hypothetical protein, conserved 0.0036 0.0085 0.1717
Loa Loa (eye worm) jmjC domain-containing protein 0.0045 0.0115 0.0115
Leishmania major ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative 0.0048 0.0126 0.2558
Brugia malayi Peptidase family M1 containing protein 0.0153 0.0493 0.1078
Trypanosoma brucei unspecified product 0.0044 0.0114 0.2307
Brugia malayi CHD4 protein 0.0016 0.0015 0.0032
Onchocerca volvulus Heterochromatin protein 1 homolog 0.0047 0.0124 0.1009
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0012 0.0002 0.0002
Brugia malayi Protein kinase domain containing protein 0.0019 0.0028 0.006
Loa Loa (eye worm) hypothetical protein 0.0047 0.0122 0.0122
Trypanosoma brucei ubiquitin carboxyl-terminal hydrolase, putative 0.0048 0.0126 0.2558
Schistosoma mansoni cytosol alanyl aminopeptidase (M01 family) 0.0153 0.0493 0.0493
Leishmania major DNA polymerase eta, putative 0.0051 0.0136 0.2762
Trypanosoma brucei DNA polymerase kappa, putative 0.0096 0.0295 0.5975
Loa Loa (eye worm) peptidase family M1 containing protein 0.0153 0.0493 0.0493
Trichomonas vaginalis D-aminoacylase, putative 0.0036 0.0085 0.1581
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0017 0.0021 0.0261
Entamoeba histolytica hypothetical protein 0.0014 0.0008 0.0161
Leishmania major DNA polymerase kappa, putative 0.002 0.0029 0.0592
Brugia malayi TATA binding protein associated factor 0.0153 0.0493 0.1078
Schistosoma mansoni SET domain protein 0.0016 0.0014 0.0014
Toxoplasma gondii LsmAD domain-containing protein 0.0051 0.0138 0.2802
Echinococcus granulosus thioredoxin glutathione reductase 0.0046 0.0121 0.0121
Schistosoma mansoni disco-interacting protein 2 (dip2) 0.0047 0.0122 0.0122
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0016 0.0015 0.0306
Echinococcus multilocularis endonuclease exonuclease phosphatase 0.0232 0.0766 0.0766
Echinococcus multilocularis neuropeptide receptor A26 0.0563 0.1918 0.1918
Mycobacterium tuberculosis Putative ferredoxin reductase 0.0104 0.0323 0.4147
Toxoplasma gondii exonuclease III APE 0.0023 0.0039 0.0791
Entamoeba histolytica recQ family helicase, putative 0.0023 0.0039 0.0799
Plasmodium vivax dihydrolipoyl dehydrogenase, mitochondrial, putative 0.0016 0.0015 0.0158
Echinococcus granulosus ubiquitin specific protease 41 0.0048 0.0126 0.0126
Plasmodium vivax DNA repair protein REV1, putative 0.002 0.0029 0.0449
Mycobacterium ulcerans DNA polymerase IV 0.0096 0.0295 0.5848
Loa Loa (eye worm) hypothetical protein 0.0014 0.0008 0.0008
Mycobacterium tuberculosis NAD(P)H quinone reductase LpdA 0.0116 0.0363 0.4693
Brugia malayi Protein cec-1. 0.0014 0.0008 0.0017
Leishmania major aminopeptidase-like protein,metallo-peptidase, Clan MA(E), Family M1 0.0153 0.0493 1
Brugia malayi beta-lactamase 0.0036 0.0085 0.0185
Trypanosoma brucei Aminopeptidase M1, putative 0.0153 0.0493 1
Schistosoma mansoni jumonji/arid domain-containing protein 0.0045 0.0115 0.0115
Toxoplasma gondii pyruvate dehydrogenase complex subunit PDH-E3II 0.0016 0.0015 0.0306
Brugia malayi jmjC domain containing protein 0.0045 0.0115 0.0252
Echinococcus multilocularis thioredoxin glutathione reductase 0.0046 0.0121 0.0121
Leishmania major aminopeptidase, putative,metallo-peptidase, Clan MA(E), Family M1 0.0153 0.0493 1
Trypanosoma cruzi trypanothione reductase, putative 0.0046 0.0119 0.2411
Trypanosoma brucei DNA polymerase kappa, putative 0.0096 0.0295 0.5975
Mycobacterium ulcerans hypothetical protein 0.002 0.0029 0.0295
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0022 0.0035 0.0563
Toxoplasma gondii aminopeptidase N protein 0.0153 0.0493 1
Trichomonas vaginalis conserved hypothetical protein 0.0047 0.0124 0.2394
Giardia lamblia Endonuclease/Exonuclease/phosphatase 0.0023 0.0039 0.0699
Plasmodium vivax hypothetical protein, conserved 0.0014 0.0008 0.0011
Echinococcus granulosus protein kinase c epsilon type 0.0017 0.0019 0.0019
Loa Loa (eye worm) pigment dispersing factor receptor c 0.006 0.017 0.017
Echinococcus multilocularis RNA directed DNA polymerase 0.0041 0.0104 0.0104
Echinococcus granulosus peregrin 0.0051 0.0137 0.0137
Onchocerca volvulus 0.0014 0.0008 0.0064
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0016 0.0015 0.0306
Mycobacterium ulcerans hypothetical protein 0.0036 0.0085 0.1455
Trichomonas vaginalis ap endonuclease, putative 0.0023 0.0039 0.0641
Mycobacterium tuberculosis Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras 0.0116 0.0363 0.4693
Echinococcus granulosus transcription factor Dp 1 0.0046 0.0121 0.0121
Echinococcus granulosus Polycystic kidney disease protein 0.0024 0.0043 0.0043
Plasmodium falciparum conserved Plasmodium protein, unknown function 0.0014 0.0008 0.0011
Echinococcus granulosus ATP dependent DNA helicase Q1 0.0047 0.0122 0.0122
Echinococcus granulosus ATP dependent DNA helicase Q5 0.0047 0.0122 0.0122
Schistosoma mansoni blooms syndrome DNA helicase 0.0055 0.0151 0.0151
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0012 0.0002 0.0002
Brugia malayi latrophilin 2 splice variant baaae 0.0041 0.0103 0.0226
Schistosoma mansoni hypothetical protein 0.0348 0.1171 0.1171
Trypanosoma cruzi apurinic/apyrimidinic endonuclease 0.0023 0.0039 0.0791
Echinococcus granulosus lipoxygenase domain containing protein 0.0024 0.0043 0.0043
Trypanosoma brucei DNA polymerase kappa, putative 0.0052 0.0141 0.2857
Echinococcus granulosus puromycin sensitive aminopeptidase 0.0153 0.0493 0.0493
Loa Loa (eye worm) hypothetical protein 0.0024 0.0043 0.0043
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0036 0.0085 0.0085
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0075 0.0221 0.0221
Echinococcus granulosus Transcription factor JmjC domain containing protein 0.0115 0.0361 0.0361
Echinococcus granulosus chromodomain helicase DNA binding protein 1 0.0014 0.0008 0.0008
Plasmodium falciparum M1-family alanyl aminopeptidase 0.0153 0.0493 1
Toxoplasma gondii hypothetical protein 0.0102 0.0316 0.6397
Plasmodium falciparum conserved Plasmodium protein, unknown function 0.0102 0.0316 0.6342
Loa Loa (eye worm) hypothetical protein 0.0153 0.0493 0.0493
Echinococcus multilocularis chromobox protein 2 0.0014 0.0008 0.0008
Echinococcus multilocularis chromobox protein 1 0.0084 0.0253 0.0253
Echinococcus granulosus polycomb protein SCMH1 0.0058 0.016 0.016
Loa Loa (eye worm) hypothetical protein 0.0153 0.0493 0.0493
Plasmodium vivax M1-family alanyl aminopeptidase, putative 0.0153 0.0493 1
Mycobacterium tuberculosis Probable dehydrogenase 0.0104 0.0323 0.4147
Trichomonas vaginalis DNA helicase recq1, putative 0.0079 0.0234 0.4654
Plasmodium falciparum glutathione reductase 0.0046 0.0119 0.2296
Echinococcus granulosus puromycin sensitive aminopeptidase 0.0153 0.0493 0.0493
Echinococcus multilocularis GPCR, family 2 0.0019 0.0026 0.0026
Trypanosoma brucei hypothetical protein, conserved 0.002 0.0029 0.0592
Plasmodium falciparum dihydrolipoyl dehydrogenase, mitochondrial 0.0016 0.0015 0.0158
Loa Loa (eye worm) hypothetical protein 0.0014 0.0008 0.0008
Echinococcus granulosus terminal deoxycytidyl transferase rev1 0.0064 0.0183 0.0183
Plasmodium vivax ATP-dependent DNA helicase Q1, putative 0.0023 0.0039 0.0658
Brugia malayi beta-lactamase family protein 0.0036 0.0085 0.0185
Trichomonas vaginalis bromodomain-containing protein, putative 0.0051 0.0139 0.2703
Mycobacterium tuberculosis Conserved protein 0.0036 0.0085 0.0939
Trypanosoma brucei DNA polymerase kappa, putative 0.0096 0.0295 0.5975
Trypanosoma brucei DNA damage repair protein, putative 0.002 0.0029 0.0592
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0022 0.0035 0.0563
Loa Loa (eye worm) ATP-dependent DNA helicase 0.0047 0.0122 0.0122
Loa Loa (eye worm) hypothetical protein 0.0048 0.0126 0.0126
Schistosoma mansoni DNA polymerase IV / kappa 0.002 0.0029 0.0029
Plasmodium vivax AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0023 0.0039 0.0651
Echinococcus multilocularis histone lysine N methyltransferase, H3 lysine 36 0.0014 0.0007 0.0007
Mycobacterium tuberculosis Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) 0.0023 0.0039 0.0323
Trypanosoma cruzi puromycin-sensitive aminopeptidase-like protein, putative 0.0153 0.0493 1
Onchocerca volvulus 0.0037 0.0089 0.0721
Echinococcus multilocularis puromycin sensitive aminopeptidase 0.0153 0.0493 0.0493
Schistosoma mansoni chromobox protein-related (chromobox 1) (heterochromatin 1) 0.0014 0.0008 0.0008
Trichomonas vaginalis conserved hypothetical protein 0.0048 0.0126 0.2436
Schistosoma mansoni aminopeptidase PILS (M01 family) 0.0155 0.0501 0.0501
Echinococcus granulosus neuropeptide receptor A26 0.0563 0.1918 0.1918
Mycobacterium ulcerans DNA polymerase IV 0.0096 0.0295 0.5848
Echinococcus granulosus serine:threonine protein kinase PLK1 0.0114 0.0358 0.0358
Trichomonas vaginalis conserved hypothetical protein 0.0033 0.0076 0.1407
Onchocerca volvulus 0.0058 0.016 0.1305
Echinococcus multilocularis ATP dependent DNA helicase Q5 0.0047 0.0122 0.0122
Brugia malayi protein kinase C II. 0.0017 0.0019 0.0042
Schistosoma mansoni ap endonuclease 0.0023 0.0039 0.0039
Echinococcus granulosus arachidonate 5 lipoxygenase 0.0142 0.0456 0.0456
Loa Loa (eye worm) latrophilin receptor protein 2 0.0019 0.0026 0.0026
Toxoplasma gondii aminopeptidase n, putative 0.0153 0.0493 1
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.0036 0.0085 0.0939
Treponema pallidum exodeoxyribonuclease (exoA) 0.0023 0.0039 0.8721
Onchocerca volvulus 0.0047 0.0122 0.0991
Onchocerca volvulus 0.0153 0.0493 0.4011
Trypanosoma brucei PHD-zinc-finger like domain containing protein, putative 0.0012 0.0000052861 0.0001
Plasmodium falciparum thioredoxin reductase 0.0016 0.0015 0.0158
Echinococcus granulosus histone lysine N methyltransferase H3 lysine 36 0.0014 0.0007 0.0007
Trypanosoma brucei metallo-peptidase, Clan MA(E) Family M1 0.0153 0.0493 1
Trypanosoma cruzi aminopeptidase, putative 0.0153 0.0493 1
Trypanosoma brucei DNA damage repair protein, putative 0.002 0.0029 0.0592
Trichomonas vaginalis CAMK family protein kinase 0.0114 0.0358 0.7204
Brugia malayi chromobox protein homolog 3 0.0047 0.0124 0.0271
Schistosoma mansoni hypothetical protein 0.0012 0.0000052861 0.0000052861
Echinococcus multilocularis neuropeptide receptor 0.0114 0.0358 0.0358
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0022 0.0035 0.0563
Leishmania major modification methylase-like protein 0.0024 0.0043 0.0872
Brugia malayi SEA domain containing protein 0.0018 0.0023 0.005
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0014 0.0008 0.0000000013755
Trypanosoma brucei DNA polymerase kappa, putative 0.0072 0.0211 0.4272
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0092 0.0281 0.0281
Leishmania major 2-oxoglutarate dehydrogenase, e3 component, lipoamidedehydrogenase-like protein 0.0016 0.0015 0.0306
Mycobacterium ulcerans esterase/lipase LipP 0.0036 0.0085 0.1455
Schistosoma mansoni aldehyde dehydrogenase 0.0063 0.0179 0.0179
Schistosoma mansoni serine/threonine protein kinase 0.0017 0.0019 0.0019
Brugia malayi ATP-dependent DNA helicase, RecQ family protein 0.0047 0.0122 0.0267
Plasmodium falciparum DNA repair protein REV1, putative 0.002 0.0029 0.0449
Trichomonas vaginalis Clan MA, family M1, aminopeptidase N-like metallopeptidase 0.0153 0.0493 1
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0016 0.0015 0.0306
Trypanosoma cruzi trypanothione reductase, putative 0.0016 0.0015 0.0306
Onchocerca volvulus 0.0019 0.0028 0.0225
Trypanosoma cruzi metallo-peptidase, clan MA(E), family M1, putative 0.0153 0.0493 1
Plasmodium vivax M1-family alanyl aminopeptidase, putative 0.0153 0.0493 1
Echinococcus multilocularis puromycin sensitive aminopeptidase 0.0153 0.0493 0.0493
Trypanosoma brucei DNA polymerase IV, putative 0.0088 0.0267 0.5413
Trypanosoma cruzi polo-like protein kinase, putative 0.0114 0.0358 0.7249
Trypanosoma brucei trypanothione reductase 0.0046 0.0119 0.2411
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.006 0.017 0.037
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0016 0.0015 0.0306
Schistosoma mansoni cpg binding protein 0.0077 0.0228 0.0228
Leishmania major aminopeptidase, putative,metallo-peptidase, Clan MA(E), Family M1 0.0153 0.0493 1
Brugia malayi PHD-finger family protein 0.0013 0.0007 0.0015
Loa Loa (eye worm) hypothetical protein 0.013 0.0411 0.0411
Loa Loa (eye worm) hypothetical protein 0.0066 0.0188 0.0188
Schistosoma mansoni myelin transcription factor 1 myt1 0.0066 0.0188 0.0188
Loa Loa (eye worm) hypothetical protein 0.0051 0.0138 0.0138
Brugia malayi exodeoxyribonuclease III family protein 0.0023 0.0039 0.0085
Schistosoma mansoni jumonji/arid domain-containing protein 0.0045 0.0115 0.0115
Trypanosoma cruzi polo-like protein kinase, putative 0.0114 0.0358 0.7249
Toxoplasma gondii histone lysine methyltransferase SET1 0.0071 0.0208 0.422
Trypanosoma cruzi tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.008 0.0237 0.4812
Plasmodium falciparum chromodomain-helicase-DNA-binding protein 1 homolog, putative 0.0014 0.0008 0.0011
Loa Loa (eye worm) hypothetical protein 0.0036 0.0085 0.0085
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0019 0.0026 0.0026
Loa Loa (eye worm) histone methyltransferase 0.0012 0.0002 0.0002
Brugia malayi Bromodomain containing protein 0.0039 0.0097 0.0213
Echinococcus multilocularis beta LACTamase domain containing family member 0.0036 0.0085 0.0085
Mycobacterium ulcerans beta-lactamase 0.0036 0.0085 0.1455
Schistosoma mansoni polycystin 1-related 0.0024 0.0043 0.0043
Schistosoma mansoni scm-relatedprotein containing 4 mbt domains (sfmbt) 0.0058 0.016 0.016
Plasmodium falciparum M1-family alanyl aminopeptidase, putative 0.0153 0.0493 1
Loa Loa (eye worm) hypothetical protein 0.0019 0.0028 0.0028
Loa Loa (eye worm) hypothetical protein 0.0019 0.0028 0.0028
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 8 0.0048 0.0126 0.0126
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0016 0.0015 0.0306
Loa Loa (eye worm) TATA binding protein associated factor 0.0153 0.0493 0.0493
Trichomonas vaginalis conserved hypothetical protein 0.0047 0.0124 0.2394
Mycobacterium tuberculosis Probable esterase LipL 0.0036 0.0085 0.0939
Loa Loa (eye worm) hypothetical protein 0.0047 0.0124 0.0124
Echinococcus granulosus puromycin sensitive aminopeptidase 0.0153 0.0493 0.0493
Trichomonas vaginalis penicillin-binding protein, putative 0.0036 0.0085 0.1581
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0036 0.0085 0.0185
Mycobacterium tuberculosis Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB 0.0104 0.0323 0.4147
Echinococcus granulosus SAM and MBT domain containing protein 0.0058 0.016 0.016
Mycobacterium leprae PROBABLE NADH DEHYDROGENASE NDH 0.0104 0.0323 0.8547
Brugia malayi mbt repeat family protein 0.0058 0.016 0.0351
Brugia malayi SET domain containing protein 0.0016 0.0015 0.0033
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0092 0.0281 0.0281
Brugia malayi Calcitonin receptor-like protein seb-1 0.006 0.017 0.037
Schistosoma mansoni lipoxygenase 0.0142 0.0456 0.0456
Mycobacterium ulcerans lipase LipD 0.0036 0.0085 0.1455
Trichomonas vaginalis ap endonuclease, putative 0.0023 0.0039 0.0641
Plasmodium falciparum phd finger protein, putative 0.0035 0.0083 0.1546
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase domain containing protein 0.0048 0.0126 0.2558
Mycobacterium ulcerans aminopeptidase N PepN 0.0153 0.0493 1
Echinococcus granulosus Chromo domain 0.0014 0.0008 0.0008
Trypanosoma brucei DNA polymerase IV, putative 0.0096 0.0295 0.5975
Trypanosoma cruzi metallo-peptidase, Clan MA(E) Family M1 0.0153 0.0493 1
Echinococcus multilocularis chromodomain helicase DNA binding protein 4 0.0016 0.0015 0.0015
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0018 0.0023 0.0302
Plasmodium vivax multidomain scavenger receptor, putative 0.0024 0.0043 0.073

Activities

Activity type Activity value Assay description Source Reference
AC50 (binding) 8.26 uM PubChem BioAssay. Development of Small Molecule Probes of the Histone Methyltransferase, NSD2 Measured in Biochemical System Using Plate Reader - 7053-01_Inhibitor_Dose_CherryPick_Activity. (Class of assay: confirmatory) ChEMBL. No reference
AC50 (functional) = 9.966 uM PUBCHEM_BIOASSAY: MITF Measured in Cell-Based System Using Plate Reader - 2084-01_Inhibitor_DoseNoFile_CherryPick_Activity_Set2. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID488944] ChEMBL. No reference
AC50 (functional) = 9.966 uM PUBCHEM_BIOASSAY: MITF Measured in Cell-Based System Using Plate Reader - 2084-01_Inhibitor_DoseNoFile_CherryPick_Activity_Set4. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID488944] ChEMBL. No reference
AC50 (functional) = 9.966 uM PUBCHEM_BIOASSAY: MITF Measured in Cell-Based System Using Plate Reader - 2084-01_Inhibitor_DoseNoFile_CherryPick_Activity_Set3. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID488944] ChEMBL. No reference
EC50 (functional) > 20 uM PUBCHEM_BIOASSAY: uHTS luminescence assay for the identification of compounds that inhibit NOD2. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID1575, AID1578, AID1579, AID1848, AID1849, AID1852, AID2001, AID2260, AID2264, AID2334, AID2335, AID2337, AID2466, AID2475, AID2485, AID2503, AID2793, AID2798, AID2799] ChEMBL. No reference
EC50 (functional) > 20 uM PUBCHEM_BIOASSAY: uHTS luminescence assay for the identification of compounds that inhibit NOD1. uHTS luminescence assay for the identification of compounds that inhibit NOD1, utilizing an NF-kB-mediated luciferase reporter gene activity as a measure of NOD1 modulation (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID1566, AID1575, AID1849, AID1852, AID2250, AID2255, AID2260, AID2261, AID2264, AID2333, AID2334, AID2335, AID2337, AID2466, AID2469, AID2475, AID2483, AID2485, AID2503, AID2505, AID2789, AID2792, AID2793, AID2798, AID2799, AID2800, AID2801] ChEMBL. No reference
IC50 (functional) = 8.31 uM PUBCHEM_BIOASSAY: Dose response confirmation of DNMT1 inhibitors in a Fluorescent Molecular Beacon assay. (Class of assay: confirmatory) ChEMBL. No reference
IC50 (functional) = 18.801 uM PUBCHEM_BIOASSAY: HTS dose response assay for identification of inhibitors of TNFa-specific NF-kB induction. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID1566, AID1575, AID1578, AID1579, AID1852, AID2337] ChEMBL. No reference
IC50 (functional) > 20 uM PUBCHEM_BIOASSAY: uHTS Fluorescence assay for the identification of cytotoxic compounds among compounds active in NOD1 cell inhibition assay. Cytotoxicity counterscreen. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID1566, AID1575, AID1578, AID1852, AID2001, AID2260, AID2264, AID2334, AID2335, AID2466, AID2469, AID2475, AID2503, AID2793, AID2798, AID2799, AID2800] ChEMBL. No reference
IC50 (functional) > 20 uM PUBCHEM_BIOASSAY: uHTS Fluorescence assay for the identification of cytotoxic compounds among compounds active in NOD2 cell inhibition assay. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID1566, AID1579, AID2260, AID2334, AID2335, AID2475, AID2503, AID2799, AID2800] ChEMBL. No reference
IC50 (functional) > 20 uM PUBCHEM_BIOASSAY: uHTS luminescence assay for the identification of compounds that inhibit NOD2 in MDP treated cells. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID1566, AID1579, AID1849, AID2260, AID2335, AID2469, AID2503, AID2800] ChEMBL. No reference
Potency (functional) 0.4654 uM PUBCHEM_BIOASSAY: Primary qHTS for delayed death inhibitors of the malarial parasite plastid, 96 hour incubation. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID488745, AID488752, AID488774, AID504848, AID504850] ChEMBL. No reference
Potency (functional) 0.5623 uM PUBCHEM_BIOASSAY: qHTS Assay for Inhibitors of GCN5L2. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID504398] ChEMBL. No reference
Potency (functional) 2.5119 uM PUBCHEM_BIOASSAY: qHTS for Inhibitors of Polymerase Eta. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID588636] ChEMBL. No reference
Potency (functional) = 3.5481 um PUBCHEM_BIOASSAY: qHTS Assay for the Inhibitors of Schistosoma Mansoni Peroxiredoxins. (Class of assay: confirmatory) [Related pubchem assays: 1011 (Confirmation Concentration-Response Assay for Inhibitors of the Schistosoma mansoni Redox Cascade ), 448 (Schistosoma Mansoni Peroxiredoxins (Prx2) and thioredoxin glutathione reductase (TGR) coupled assay)] ChEMBL. No reference
Potency (functional) 4.7444 uM PUBCHEM_BIOASSAY: qHTS Assay for the Inhibitors of L3MBTL1: Hit Validation. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID485292] ChEMBL. No reference
Potency (functional) 4.7444 uM PubChem BioAssay. qHTS for Inhibitors of PLK1-PDB (polo-like kinase 1 - polo-box domain): Primary Screen. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) 5.6234 uM PubChem BioAssay. qHTS for Antagonists of gsp, the Etiologic Mutation Responsible for Fibrous Dysplasia/McCune-Albright Syndrome: qHTS. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) 7.9433 uM PUBCHEM_BIOASSAY: CHOP2 Reporter Counterscreen Assay for Inhibitors of Ubiquitin-specific Protease USP2a. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID2281, AID463106, AID463254] ChEMBL. No reference
Potency (functional) 8.5683 uM PubChem BioAssay. qHTS for Inhibitors of WRN Helicase: BLM Helicase Counterscreen for WRN Inhibitors. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) 9.2 uM PubChem BioAssay. A quantitative high throughput screen for small molecules that induce DNA re-replication in MCF 10a normal breast cells. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) 9.5283 uM PubChem BioAssay. qHTS for Inhibitors of Polymerase Eta: Confirmatory Assay for Cherry-picked Compounds. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) = 10 um PUBCHEM_BIOASSAY: qHTS Assay for Inhibitors of RecQ-Like Dna Helicase 1 (RECQ1). (Class of assay: confirmatory) [Related pubchem assays: 594 (Rhodamine region spectral profiling screen), 593 (Fluorescein region spectral profiling screen), 2367 (Probe Development Summary for Inhibitors of RecQ-Like Dna Helicase 1 (RECQ1)), 2353 (qHTS Validation Assay for Inhibitors of RecQ-Like Dna Helicase 1 (RECQ1))] ChEMBL. No reference
Potency (functional) = 10 um PUBCHEM_BIOASSAY: qHTS Assay for Antagonists of the Neuropeptide S Receptor: cAMP Signal Transduction. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) 11.2202 uM PUBCHEM_BIOASSAY: qHTS for Inducers of the Endoplasmic Reticulum Stress Response (ERSR) in Human Glioma: qHTS. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) 12.5893 uM PUBCHEM_BIOASSAY: Ub-rhodamine 110 based assay for inhibitors Ubiquitin-specific Protease USP2a. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID2281, AID463106, AID463254] ChEMBL. No reference
Potency (functional) 12.5893 uM PubChem BioAssay. qHTS of GLP-1 Receptor Agonists. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) 14.0441 uM PubChem BioAssay. qHTS for inhibitors of Vif-A3F interactions: Cherry picks. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) 14.1254 uM PUBCHEM_BIOASSAY: qHTS Assay for Inhibitors of JMJD2A-Tudor Domain. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID504402] ChEMBL. No reference
Potency (functional) 14.6892 uM PUBCHEM_BIOASSAY: Confirmation Assay for Inhibitors of Ubiquitin-specific Protease USP2a Using CHOP2 as the Reporter. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID2281, AID463106, AID463254] ChEMBL. No reference
Potency (functional) = 15.8489 um PUBCHEM_BIOASSAY: qHTS for Inhibitors of Tau Fibril Formation, Fluorescence Polarization. (Class of assay: confirmatory) [Related pubchem assays: 596 ] ChEMBL. No reference
Potency (functional) 17.0961 uM PubChem BioAssay. qHTS for Inhibitors of WRN Helicase: Confirmatory Assay for Cherry-picked Compounds.. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) 17.7828 uM PUBCHEM_BIOASSAY: qHTS for Inhibitors of Vif-A3F Interactions: qHTS. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) 18.8876 uM PubChem BioAssay. qHTS for Inhibitors of Polymerase Iota: Confirmatory Assay for Cherry-picked Compounds. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) = 19.9526 um PUBCHEM_BIOASSAY: qHTS Assay for Inhibitors of Ubiquitin-specific Protease USP2a Using CHOP2 as the Reporter. (Class of assay: confirmatory) [Related pubchem assays: 2281 (Summary of qHTS Assay for Inhibitors of Ubiquitin-specific Protease USP2a), 463106 (LOPAC Validation Assay for Inhibitors of Ubiquitin-specific Protease USP2a)] ChEMBL. No reference
Potency (functional) 19.9526 uM PUBCHEM_BIOASSAY: qHTS Assay for Inhibitors of 15-hLO-2 (15-human lipoxygenase 2). (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID2312, AID2537, AID2702] ChEMBL. No reference
Potency (functional) 22.2584 uM PubChem BioAssay. qHTS for inhibitors of Vif-A3G interactions: Cherry picks counterscreen. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) = 22.3872 um PUBCHEM_BIOASSAY: qHTS Assay for Inhibitors Targeting the Menin-MLL Interaction in MLL Related Leukemias: Competition With Fluorescein Labeled MLL-derived Peptide. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) = 22.3872 um PUBCHEM_BIOASSAY: qHTS Assay for Inhibitors of Aldehyde Dehydrogenase 1 (ALDH1A1). (Class of assay: confirmatory) [Related pubchem assays: 1030 (qHTS Validation Assay for Inhibitors of aldehyde dehydrogenase 1 (ALDH1A1))] ChEMBL. No reference
Potency (functional) = 22.3872 um PUBCHEM_BIOASSAY: qHTS Assay for Inhibitors of DNA Polymerase Beta. (Class of assay: confirmatory) ChEMBL. No reference
Potency (binding) 22.3872 uM PUBCHEM_BIOASSAY: qHTS Assay for Compounds Blocking the Interaction Between CBF-beta and RUNX1 for the Treatment of Acute Myeloid Leukemia. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID1484, AID504370, AID504374, AID504375] ChEMBL. No reference
Potency (functional) 22.3872 uM PUBCHEM_BIOASSAY: qHTS for Inhibitors of Polymerase Kappa. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID588638] ChEMBL. No reference
Potency (functional) 22.3872 uM PubChem BioAssay. qHTS for Inhibitors of Glutaminase (GLS). (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) 22.3872 uM PubChem BioAssay. qHTS for Inhibitors of Vif-A3G Interactions: qHTS. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) 22.3872 uM PUBCHEM_BIOASSAY: qHTS for Inhibitors of binding or entry into cells for Lassa Virus. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID463114, AID540249] ChEMBL. No reference
Potency (functional) 24.9744 uM PubChem BioAssay. qHTS for inhibitors of Vif-A3G interactions: Cherry picks. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) 24.9744 uM PubChem BioAssay. qHTS for inhibitors of Vif-A3F interactions: Cherry picks counterscreen. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) = 25.1189 um PUBCHEM_BIOASSAY: qHTS Assay for Modulators of Lamin A Splicing. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) = 25.1189 um PUBCHEM_BIOASSAY: qHTS Multiplex Assay to Identify Dual Action Probes in a Cell Model of Huntington: Aggregate Formation (GFP). (Class of assay: confirmatory) [Related pubchem assays: 1482, 1471 ] ChEMBL. No reference
Potency (functional) 25.1189 uM PubChem BioAssay. qHTS Assay for Inhibitors of the Human Apurinic/apyrimidinic Endonuclease 1 (APE1). (Class of assay: confirmatory) ChEMBL. No reference
Potency (binding) = 28.1838 um PUBCHEM_BIOASSAY: qHTS for Inhibitors of Tau Fibril Formation, Thioflavin T Binding. (Class of assay: confirmatory) [Related pubchem assays: 596 ] ChEMBL. No reference
Potency (functional) = 28.1838 um PUBCHEM_BIOASSAY: qHTS Assay for Inhibitors of Bloom's syndrome helicase (BLM). (Class of assay: confirmatory) [Related pubchem assays: 593 (Fluorescein region spectral profiling screen), 2386 (Probe Development Summary for Inhibitors of Bloom's syndrome helicase (BLM)), 594 (Rhodamine region spectral profiling screen), 2364 (qHTS Validation Assay for Inhibitors of Bloom's syndrome helicase (BLM))] ChEMBL. No reference
Potency (functional) 28.1838 uM PUBCHEM_BIOASSAY: HTS for Inhibitors of HP1-beta Chromodomain Interactions with Methylated Histone Tails. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID488962] ChEMBL. No reference
Potency (functional) 28.1838 uM PubChem BioAssay. qHTS for Agonist of gsp, the Etiologic Mutation Responsible for Fibrous Dysplasia/McCune-Albright Syndrome: qHTS. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) 29.0929 uM PUBCHEM_BIOASSAY: qHTS screen for small molecules that inhibit ELG1-dependent DNA repair in human embryonic kidney (HEK293T) cells expressing luciferase-tagged ELG1. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID493107, AID493125] ChEMBL. No reference
Potency (functional) 29.0929 uM PubChem BioAssay. A quantitative high throughput screen for small molecules that induce DNA re-replication in SW480 colon adenocarcinoma cells. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) 29.0929 uM PubChem BioAssay. qHTS for induction of synthetic lethality in tumor cells producing 2HG: qHTS for the HT-1080-NT fibrosarcoma cell line. (Class of assay: confirmatory) ChEMBL. No reference
Potency (binding) = 31.6228 um PUBCHEM_BIOASSAY: qHTS Assay for Identification of Novel General Anesthetics. In this assay, a GABAergic mimetic model system, apoferritin and a profluorescent 1-aminoanthracene ligand (1-AMA), was used to construct a competitive binding assay for identification of novel general anesthetics (Class of assay: confirmatory) [Related pubchem assays: 2385 (Probe Development Summary for Identification of Novel General Anesthetics), 2323 (Validation apoferritin assay run on SigmaAldrich LOPAC1280 collection)] ChEMBL. No reference
Potency (functional) = 31.6228 um PUBCHEM_BIOASSAY: qHTS Assay for Inhibitors of 12-hLO (12-human lipoxygenase). (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) = 31.6228 um PUBCHEM_BIOASSAY: qHTS Assay for the Inhibitors of L3MBTL1. (Class of assay: confirmatory) [Related pubchem assays: 485292 (Probe Development Summary for Inhibitors of L3MBTL1)] ChEMBL. No reference
Potency (functional) = 31.6228 um PUBCHEM_BIOASSAY: qHTS Assay for Inhibitors of HPGD (15-Hydroxyprostaglandin Dehydrogenase). (Class of assay: confirmatory) [Related pubchem assays: 2429 (Confirmation qHTS Assay for Inhibitors of HPGD (15-Hydroxyprostaglandin Dehydrogenase)), 2407 (Probe Development Summary for Inhibitors of HPGD (15-Hydroxyprostaglandin Dehydrogenase)), 2427 (Thermal Shift Assay for Inhibitors of HPGD (15-Hydroxyprostaglandin Dehydrogenase))] ChEMBL. No reference
Potency (functional) 31.6228 uM PUBCHEM_BIOASSAY: qHTS for Inhibitors of Polymerase Iota. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID588623] ChEMBL. No reference
Potency (functional) 31.6228 uM PUBCHEM_BIOASSAY: qHTS Assay to Find Inhibitors of Phosphoglycerate Kinase. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) 31.6228 uM PubChem BioAssay. qHTS of Nrf2 Activators. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) = 35.4813 um PUBCHEM_BIOASSAY: VP16 counterscreen qHTS for inhibitors of ROR gamma transcriptional activity. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) = 35.4813 um PUBCHEM_BIOASSAY: qHTS for inhibitors of ROR gamma transcriptional activity. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) 35.4813 uM PUBCHEM_BIOASSAY: qHTS Assay for Inhibitors of BAZ2B. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID504391] ChEMBL. No reference
Potency (functional) 35.4813 uM PubChem BioAssay. qHTS for Inhibitors of WRN Helicase. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) 37.933 uM PubChem BioAssay. qHTS Assay to Find Inhibitors of Pin1. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) 39.8107 uM PubChem BioAssay. qHTS for Inhibitors of ATXN expression. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) 39.8107 uM PubChem BioAssay. qHTS for Small Molecule Inhibitors of the ERG Ets/DNA interaction. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) 50.1187 uM PubChem BioAssay. qHTS for Antagonist of cAMP-regulated guanine nucleotide exchange factor 3 (EPAC1): primary screen. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) 56.2341 uM PUBCHEM_BIOASSAY: qHTS Assay for the Inhibitors of Human Flap endonuclease 1 (FEN1). (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID488813] ChEMBL. No reference
Potency (functional) 63.0957 uM PUBCHEM_BIOASSAY: qHTS Assay for Inhibitors of Rango (Ran-regulated importin-beta cargo) - Importin beta complex formation. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID540273] ChEMBL. No reference
Potency (functional) 223.8721 uM PubChem BioAssay. Inhibitors of Secretory Acid Sphingomyelinase (S-ASM): qHTS. (Class of assay: confirmatory) ChEMBL. No reference

Phenotypes

Whole-cell/tissue/organism interactions

Species name Source Reference Is orphan
Homo sapiens ChEMBL23
Plasmodium falciparum ChEMBL23

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

Bibliographic References

No literature references available for this target.

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