Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Trypanosoma cruzi | DNA polymerase epsilon catalytic subunit, putative | 0.0142 | 0.1167 | 0.1804 |
Echinococcus granulosus | thioredoxin glutathione reductase | 0.0037 | 0.0143 | 0.0468 |
Brugia malayi | RNase H family protein | 0.0101 | 0.0761 | 0.2491 |
Trypanosoma brucei | DNA polymerase alpha catalytic subunit | 0.0172 | 0.1458 | 0.1458 |
Brugia malayi | reverse transcriptase | 0.0024 | 0.0013 | 0.0042 |
Trypanosoma brucei | unspecified product | 0.0124 | 0.0992 | 0.0992 |
Onchocerca volvulus | DNA polymerase homolog | 0.0142 | 0.1167 | 0.367 |
Mycobacterium tuberculosis | NADPH-dependent mycothiol reductase Mtr | 0.0037 | 0.0138 | 0.0418 |
Loa Loa (eye worm) | hypothetical protein | 0.0115 | 0.0899 | 0.2847 |
Plasmodium falciparum | DNA polymerase delta catalytic subunit | 0.0336 | 0.3055 | 1 |
Schistosoma mansoni | thymidylate kinase | 0.0087 | 0.0631 | 0.0631 |
Trypanosoma cruzi | thymidine kinase, putative | 0.0282 | 0.253 | 0.391 |
Trypanosoma cruzi | mitochondrial DNA polymerase beta-PAK, putative | 0.0325 | 0.2947 | 0.4555 |
Trypanosoma cruzi | DNA polymerase delta catalytic subunit, putative | 0.0257 | 0.2286 | 0.3533 |
Trichomonas vaginalis | NeSL-1_NeSL reverse transcriptases, putative | 0.0024 | 0.0013 | 0.0042 |
Toxoplasma gondii | DNA polymerase family B protein | 0.0063 | 0.0398 | 0.089 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0074 | 0.05 | 0.05 |
Plasmodium vivax | DNA polymerase zeta catalytic subunit, putative | 0.0142 | 0.1167 | 0.3528 |
Brugia malayi | Zinc knuckle family protein | 0.0024 | 0.0013 | 0.0042 |
Echinococcus multilocularis | RNA directed DNA polymerase (reverse transcriptase) | 0.0024 | 0.0013 | 0.0042 |
Loa Loa (eye worm) | DNA-directed DNA polymerase III | 0.0336 | 0.3055 | 0.9675 |
Brugia malayi | reverse transcriptase | 0.0024 | 0.0013 | 0.0042 |
Echinococcus granulosus | RNA directed DNA polymerase | 0.0024 | 0.0013 | 0.0042 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0074 | 0.05 | 0.05 |
Giardia lamblia | Reverse transcriptase/endonuclease, putative | 0.0024 | 0.0013 | 0.0042 |
Trichomonas vaginalis | reverse transcriptase [C. elegans], putative | 0.0024 | 0.0013 | 0.0042 |
Trypanosoma cruzi | ribonuclease H1, putative | 0.0101 | 0.0761 | 0.1176 |
Schistosoma mansoni | DNA polymerase alpha catalytic subunit | 0.007 | 0.046 | 0.046 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.0074 | 0.05 | 0.0774 |
Toxoplasma gondii | DNA polymerase (pol2) superfamily protein | 0.0242 | 0.2137 | 0.6851 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0074 | 0.05 | 0.05 |
Chlamydia trachomatis | thymidylate kinase | 0.0087 | 0.0631 | 0.5 |
Trypanosoma brucei | retrotransposon hot spot protein 4 (RHS4), interrupted | 0.0124 | 0.0992 | 0.0992 |
Trichomonas vaginalis | DNA polymerase II, putative | 0.0172 | 0.1458 | 0.4771 |
Loa Loa (eye worm) | hypothetical protein | 0.0063 | 0.0398 | 0.126 |
Brugia malayi | Cytochrome P450 family protein | 0.003 | 0.0076 | 0.0249 |
Brugia malayi | Pao retrotransposon peptidase family protein | 0.0024 | 0.0013 | 0.0042 |
Mycobacterium tuberculosis | Possible maturase | 0.0024 | 0.0013 | 0.0039 |
Brugia malayi | DNA polymerase alpha catalytic subunit | 0.0242 | 0.2137 | 0.6993 |
Trypanosoma cruzi | DNA polymerase epsilon catalytic subunit, putative | 0.0142 | 0.1167 | 0.1804 |
Onchocerca volvulus | Putative thymidylate kinase | 0.0087 | 0.0631 | 0.1965 |
Trypanosoma cruzi | mitochondrial DNA polymerase beta, putative | 0.0686 | 0.647 | 1 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0074 | 0.05 | 0.05 |
Schistosoma mansoni | DNA polymerase zeta catalytic subunit | 0.0142 | 0.1167 | 0.1167 |
Brugia malayi | hypothetical protein | 0.0024 | 0.0013 | 0.0042 |
Onchocerca volvulus | DNA polymerase epsilon catalytic subunit A homolog | 0.0142 | 0.1167 | 0.367 |
Echinococcus multilocularis | DNA polymerase alpha catalytic subunit | 0.0277 | 0.2479 | 0.8114 |
Trypanosoma brucei | thymidylate kinase, putative | 0.0087 | 0.0631 | 0.0631 |
Mycobacterium tuberculosis | Thymidylate kinase Tmk (dTMP kinase) (thymidylic acid kinase) (TMPK) | 0.0087 | 0.0631 | 0.1909 |
Trypanosoma cruzi | DNA polymerase delta catalytic subunit, putative | 0.0336 | 0.3055 | 0.4722 |
Leishmania major | DNA polymerase delta catalytic subunit, putative | 0.0336 | 0.3055 | 0.4722 |
Giardia lamblia | Reverse transcriptase/endonuclease, putative | 0.0024 | 0.0013 | 0.0042 |
Trypanosoma cruzi | cruzipain precursor, putative | 0.0074 | 0.05 | 0.0774 |
Brugia malayi | DNA polymerase delta catalytic subunit | 0.0336 | 0.3055 | 1 |
Echinococcus granulosus | KRAB A domain containing protein | 0.0024 | 0.0013 | 0.0042 |
Leishmania major | thymidylate kinase-like protein | 0.0087 | 0.0631 | 0.0975 |
Trichomonas vaginalis | DNA polymerase delta catalytic subunit, putative | 0.0142 | 0.1167 | 0.382 |
Echinococcus multilocularis | dna polymerase epsilon catalytic subunit a | 0.0142 | 0.1167 | 0.382 |
Giardia lamblia | Thymidine kinase | 0.0282 | 0.253 | 0.828 |
Brugia malayi | Pao retrotransposon peptidase family protein | 0.0024 | 0.0013 | 0.0042 |
Schistosoma mansoni | phosphoglucomutase | 0.0101 | 0.0761 | 0.0761 |
Giardia lamblia | Ribonuclease H | 0.0101 | 0.0761 | 0.2491 |
Leishmania major | thymidine kinase, putative | 0.0282 | 0.253 | 0.391 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0074 | 0.05 | 0.05 |
Trypanosoma brucei | mitochondrial DNA polymerase beta | 0.0686 | 0.647 | 0.647 |
Onchocerca volvulus | DNA polymerase delta catalytic subunit homolog | 0.0336 | 0.3055 | 0.9673 |
Trypanosoma brucei | thymidylate kinase, putative | 0.0087 | 0.0631 | 0.0631 |
Echinococcus multilocularis | DNA polymerase zeta catalytic subunit | 0.0142 | 0.1167 | 0.382 |
Leishmania major | cathepsin L-like protease | 0.0074 | 0.05 | 0.0774 |
Mycobacterium tuberculosis | Probable membrane NADH dehydrogenase NdhA | 0.0084 | 0.0595 | 0.1802 |
Entamoeba histolytica | DNA polymerase delta catalytic subunit, putative | 0.0336 | 0.3055 | 1 |
Brugia malayi | reverse transcriptase | 0.0024 | 0.0013 | 0.0042 |
Echinococcus multilocularis | RNA directed DNA polymerase (reverse transcriptase) | 0.0024 | 0.0013 | 0.0042 |
Echinococcus granulosus | DNA polymerase delta catalytic subunit | 0.0336 | 0.3055 | 1 |
Echinococcus granulosus | DNA polymerase alpha catalytic subunit | 0.0277 | 0.2479 | 0.8114 |
Schistosoma mansoni | hypothetical protein | 0.0087 | 0.0631 | 0.0631 |
Schistosoma mansoni | thymidylate kinase | 0.0087 | 0.0631 | 0.0631 |
Brugia malayi | Pao retrotransposon peptidase family protein | 0.0024 | 0.0013 | 0.0042 |
Trichomonas vaginalis | DNA polymerase zeta catalytic subunit, putative | 0.0336 | 0.3055 | 1 |
Mycobacterium tuberculosis | Putative ferredoxin reductase | 0.0084 | 0.0595 | 0.1802 |
Leishmania major | cathepsin L-like protease | 0.0074 | 0.05 | 0.0774 |
Trypanosoma brucei | SLACS reverse transcriptase, putative | 0.0024 | 0.0013 | 0.0013 |
Trypanosoma cruzi | thymidine kinase, putative | 0.0282 | 0.253 | 0.391 |
Brugia malayi | Pao retrotransposon peptidase family protein | 0.0024 | 0.0013 | 0.0042 |
Echinococcus multilocularis | telomerase reverse transcriptase subunit | 0.0024 | 0.0013 | 0.0042 |
Leishmania major | DNA polymerase epsilon catalytic subunit, putative | 0.0142 | 0.1167 | 0.1804 |
Echinococcus granulosus | RNA directed DNA polymerase reverse transcriptase | 0.0024 | 0.0013 | 0.0042 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0063 | 0.0398 | 0.1302 |
Brugia malayi | Pao retrotransposon peptidase family protein | 0.0024 | 0.0013 | 0.0042 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0074 | 0.05 | 0.05 |
Mycobacterium tuberculosis | Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras | 0.0093 | 0.0686 | 0.2077 |
Echinococcus multilocularis | hypothetical protein | 0.0115 | 0.0899 | 0.2943 |
Echinococcus multilocularis | RNA directed DNA polymerase (reverse transcriptase) | 0.0024 | 0.0013 | 0.0042 |
Trypanosoma cruzi | UMP-CMP kinase, mitochondrial, putative | 0.0034 | 0.0115 | 0.0177 |
Echinococcus multilocularis | RNA directed DNA polymerase (reverse transcriptase) | 0.0024 | 0.0013 | 0.0042 |
Mycobacterium leprae | DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE | 0.0093 | 0.0686 | 1 |
Schistosoma mansoni | DNA polymerase delta catalytic subunit | 0.0336 | 0.3055 | 0.3055 |
Echinococcus granulosus | thymidylate kinase | 0.0087 | 0.0631 | 0.2065 |
Loa Loa (eye worm) | thymidylate kinase | 0.0087 | 0.0631 | 0.1998 |
Brugia malayi | glutathione reductase | 0.0037 | 0.0138 | 0.0452 |
Trypanosoma brucei | ingi protein (ORF1) | 0.0124 | 0.0992 | 0.0992 |
Brugia malayi | Pao retrotransposon peptidase family protein | 0.0024 | 0.0013 | 0.0042 |
Entamoeba histolytica | DNA polymerase alpha catalytic subunit, putative | 0.0093 | 0.0688 | 0.2253 |
Wolbachia endosymbiont of Brugia malayi | ribonuclease HI | 0.0101 | 0.0761 | 1 |
Echinococcus multilocularis | RNA directed DNA polymerase | 0.0024 | 0.0013 | 0.0042 |
Echinococcus multilocularis | RNA directed DNA polymerase (reverse transcriptase) | 0.0024 | 0.0013 | 0.0042 |
Echinococcus granulosus | RNA directed DNA polymerase reverse transcriptase | 0.0024 | 0.0013 | 0.0042 |
Loa Loa (eye worm) | hypothetical protein | 0.0347 | 0.3158 | 1 |
Mycobacterium tuberculosis | Conserved hypothetical protein | 0.0362 | 0.3304 | 1 |
Mycobacterium ulcerans | hypothetical protein | 0.0362 | 0.3304 | 1 |
Leishmania major | mitochondrial DNA polymerase beta | 0.0686 | 0.647 | 1 |
Trypanosoma cruzi | major cysteine proteinase, putative | 0.0058 | 0.0347 | 0.0536 |
Brugia malayi | DNA polymerase I family protein | 0.0115 | 0.0899 | 0.2943 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0074 | 0.05 | 0.05 |
Trichomonas vaginalis | ribonuclease H1, putative | 0.0101 | 0.0761 | 0.2491 |
Leishmania major | cathepsin L-like protease | 0.0074 | 0.05 | 0.0774 |
Leishmania major | trypanothione reductase | 0.0037 | 0.0138 | 0.0214 |
Toxoplasma gondii | DNA polymerase family B protein | 0.0142 | 0.1167 | 0.3528 |
Brugia malayi | hypothetical protein | 0.0024 | 0.0013 | 0.0042 |
Echinococcus multilocularis | DNA polymerase delta catalytic subunit | 0.0336 | 0.3055 | 1 |
Echinococcus granulosus | DNA polymerase subunit gamma | 0.0115 | 0.0899 | 0.2943 |
Trypanosoma brucei | hypothetical protein, conserved | 0.0124 | 0.0992 | 0.0992 |
Trypanosoma brucei | SLACS retrotransposable element (part), putative | 0.0024 | 0.0013 | 0.0013 |
Trypanosoma cruzi | DNA polymerase beta thumb, putative | 0.0097 | 0.0722 | 0.1116 |
Echinococcus multilocularis | RNA directed DNA polymerase (reverse transcriptase) | 0.0024 | 0.0013 | 0.0042 |
Onchocerca volvulus | Ribonuclease H1 homolog | 0.0101 | 0.0761 | 0.2379 |
Trichomonas vaginalis | thymidylate kinase, putative | 0.0087 | 0.0631 | 0.2065 |
Trypanosoma brucei | mitochondrial DNA polymerase beta-PAK | 0.0325 | 0.2947 | 0.2947 |
Trichomonas vaginalis | reverse transcriptases, putative | 0.0024 | 0.0013 | 0.0042 |
Trichomonas vaginalis | thymidine kinase, putative | 0.0282 | 0.253 | 0.828 |
Brugia malayi | DNA polymerase family B containing protein | 0.0142 | 0.1167 | 0.382 |
Schistosoma mansoni | DNA polymerase epsilon catalytic subunit | 0.0142 | 0.1167 | 0.1167 |
Giardia lamblia | DNA polymerase epsilon, catalytic subunit | 0.0142 | 0.1167 | 0.382 |
Mycobacterium tuberculosis | Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB | 0.0084 | 0.0595 | 0.1802 |
Brugia malayi | Pao retrotransposon peptidase family protein | 0.0024 | 0.0013 | 0.0042 |
Echinococcus granulosus | ribonuclease H1 | 0.0101 | 0.0761 | 0.2491 |
Brugia malayi | thymidylate kinase | 0.0087 | 0.0631 | 0.2065 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0074 | 0.05 | 0.05 |
Mycobacterium ulcerans | thymidylate kinase | 0.0087 | 0.0631 | 0.1909 |
Mycobacterium tuberculosis | Probable dehydrogenase | 0.0084 | 0.0595 | 0.1802 |
Schistosoma mansoni | protein kinase | 0.0024 | 0.0013 | 0.0013 |
Trichomonas vaginalis | reverse transcriptases, putative | 0.0024 | 0.0013 | 0.0042 |
Trypanosoma brucei | DNA polymerase delta catalytic subunit, putative | 0.0336 | 0.3055 | 0.3055 |
Schistosoma mansoni | hypothetical protein | 0.0024 | 0.0013 | 0.0013 |
Brugia malayi | hypothetical protein | 0.0024 | 0.0013 | 0.0042 |
Loa Loa (eye worm) | hypothetical protein | 0.0079 | 0.0551 | 0.1744 |
Trichomonas vaginalis | thymidine kinase, putative | 0.0282 | 0.253 | 0.828 |
Echinococcus multilocularis | RNA directed DNA polymerase (reverse transcriptase) | 0.0024 | 0.0013 | 0.0042 |
Entamoeba histolytica | thymidine kinase, putative | 0.0282 | 0.253 | 0.828 |
Loa Loa (eye worm) | DNA polymerase epsilon catalytic subunit | 0.0079 | 0.0551 | 0.1744 |
Brugia malayi | Pao retrotransposon peptidase family protein | 0.0024 | 0.0013 | 0.0042 |
Plasmodium vivax | DNA polymerase epsilon, catalytic subunit a, putative | 0.0142 | 0.1167 | 0.3528 |
Trypanosoma cruzi | DNA polymerase zeta catalytic subunit, putative | 0.0063 | 0.0398 | 0.0615 |
Giardia lamblia | DNA polymerase delta, catalytic subunit | 0.0336 | 0.3055 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0079 | 0.0551 | 0.1744 |
Schistosoma mansoni | hypothetical protein | 0.0024 | 0.0013 | 0.0013 |
Trypanosoma cruzi | thymidylate kinase, putative | 0.0087 | 0.0631 | 0.0975 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0074 | 0.05 | 0.05 |
Plasmodium falciparum | DNA polymerase alpha catalytic subunit A | 0.0093 | 0.0688 | 0.1886 |
Echinococcus multilocularis | RNA directed DNA polymerase (reverse transcriptase) | 0.0024 | 0.0013 | 0.0042 |
Trypanosoma cruzi | trypanothione reductase, putative | 0.0037 | 0.0138 | 0.0214 |
Schistosoma mansoni | phosphoglucomutase | 0.0101 | 0.0761 | 0.0761 |
Trypanosoma brucei | DNA polymerase epsilon catalytic subunit, putative | 0.0142 | 0.1167 | 0.1167 |
Entamoeba histolytica | Thymidylate kinase, putative | 0.0087 | 0.0631 | 0.2065 |
Mycobacterium tuberculosis | Probable oxidoreductase | 0.0093 | 0.0686 | 0.2077 |
Brugia malayi | Pao retrotransposon peptidase family protein | 0.0024 | 0.0013 | 0.0042 |
Trypanosoma cruzi | DNA polymerase I alpha catalytic subunit, putative | 0.0172 | 0.1458 | 0.2253 |
Echinococcus granulosus | dna polymerase epsilon catalytic subunit a | 0.0142 | 0.1167 | 0.382 |
Echinococcus multilocularis | thioredoxin glutathione reductase | 0.0037 | 0.0143 | 0.0468 |
Trypanosoma cruzi | mitochondrial DNA polymerase beta, putative | 0.0686 | 0.647 | 1 |
Trypanosoma brucei | ribonuclease H1 | 0.0101 | 0.0761 | 0.0761 |
Brugia malayi | Thioredoxin reductase | 0.0037 | 0.0138 | 0.0452 |
Trypanosoma brucei | trypanothione reductase | 0.0037 | 0.0138 | 0.0138 |
Brugia malayi | Pao retrotransposon peptidase family protein | 0.0024 | 0.0013 | 0.0042 |
Loa Loa (eye worm) | hypothetical protein | 0.0063 | 0.0398 | 0.126 |
Trypanosoma cruzi | mitochondrial DNA polymerase beta-PAK, putative | 0.0118 | 0.0927 | 0.1434 |
Giardia lamblia | CDC8 | 0.0087 | 0.0631 | 0.2065 |
Leishmania major | mitochondrial DNA polymerase beta-PAK, putative | 0.0325 | 0.2947 | 0.4555 |
Plasmodium falciparum | DNA polymerase zeta catalytic subunit, putative | 0.0063 | 0.0398 | 0.089 |
Schistosoma mansoni | serine/threonine protein kinase | 0.0024 | 0.0013 | 0.0013 |
Schistosoma mansoni | DNA polymerase gamma | 0.0115 | 0.0899 | 0.0899 |
Giardia lamblia | DNA polymerase alpha subunit A | 0.0198 | 0.171 | 0.5596 |
Trypanosoma cruzi | DNA polymerase beta thumb, putative | 0.0097 | 0.0722 | 0.1116 |
Plasmodium vivax | DNA polymerase alpha, putative | 0.0242 | 0.2137 | 0.6851 |
Echinococcus multilocularis | ribonuclease H1 | 0.0101 | 0.0761 | 0.2491 |
Plasmodium vivax | DNA polymerase delta catalytic subunit, putative | 0.0336 | 0.3055 | 1 |
Loa Loa (eye worm) | thioredoxin reductase | 0.0037 | 0.0138 | 0.0438 |
Echinococcus granulosus | DNA polymerase zeta catalytic subunit | 0.0142 | 0.1167 | 0.382 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0074 | 0.05 | 0.05 |
Toxoplasma gondii | DNA polymerase | 0.0336 | 0.3055 | 1 |
Trypanosoma brucei | DNA polymerase zeta catalytic subunit, putative | 0.0142 | 0.1167 | 0.1167 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0024 | 0.0013 | 0.002 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.0074 | 0.05 | 0.0774 |
Trypanosoma brucei | thymidine kinase | 0.0282 | 0.253 | 0.253 |
Brugia malayi | Pao retrotransposon peptidase family protein | 0.0024 | 0.0013 | 0.0042 |
Trichomonas vaginalis | DNA polymerase alpha catalytic subunit, putative | 0.0172 | 0.1458 | 0.4771 |
Toxoplasma gondii | thymidylate kinase | 0.0087 | 0.0631 | 0.1689 |
Trypanosoma brucei | RNA helicase, putative | 0.1049 | 1 | 1 |
Loa Loa (eye worm) | cytochrome P450 family protein | 0.003 | 0.0076 | 0.0241 |
Echinococcus multilocularis | thymidylate kinase | 0.0087 | 0.0631 | 0.2065 |
Trypanosoma brucei | ingi protein (ORF1) | 0.0124 | 0.0992 | 0.0992 |
Toxoplasma gondii | hypothetical protein | 0.0111 | 0.086 | 0.2475 |
Trichomonas vaginalis | DNA polymerase alpha catalytic subunit, putative | 0.0079 | 0.0551 | 0.1802 |
Echinococcus granulosus | RNA directed DNA polymerase reverse transcriptase | 0.0024 | 0.0013 | 0.0042 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0074 | 0.05 | 0.05 |
Trypanosoma cruzi | mitochondrial DNA polymerase beta-PAK, putative | 0.0097 | 0.0722 | 0.1116 |
Trypanosoma brucei | Endonuclease-reverse transcriptase/Reverse transcriptase (RNA-dependent DNA polymerase), putative | 0.0024 | 0.0013 | 0.0013 |
Plasmodium falciparum | thymidylate kinase | 0.0087 | 0.0631 | 0.1689 |
Leishmania major | ribonuclease H1, putative | 0.0101 | 0.0761 | 0.1176 |
Toxoplasma gondii | ribonuclease HI protein | 0.0101 | 0.0761 | 0.2135 |
Treponema pallidum | ribonuclease H (rnhA) | 0.0101 | 0.0761 | 1 |
Plasmodium vivax | thymidylate kinase, putative | 0.0087 | 0.0631 | 0.1689 |
Giardia lamblia | Reverse transcriptase/endonuclease, putative | 0.0024 | 0.0013 | 0.0042 |
Trypanosoma brucei | DNA polymerase beta thumb, putative | 0.0097 | 0.0722 | 0.0722 |
Loa Loa (eye worm) | glutathione reductase | 0.0037 | 0.0138 | 0.0438 |
Trypanosoma cruzi | ribonuclease H1, putative | 0.0101 | 0.0761 | 0.1176 |
Leishmania major | hypothetical protein, conserved | 0.0034 | 0.0115 | 0.0177 |
Entamoeba histolytica | DNA polymerase zeta catalytic subunit, putative | 0.0063 | 0.0398 | 0.1302 |
Brugia malayi | Pao retrotransposon peptidase family protein | 0.0024 | 0.0013 | 0.0042 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.0074 | 0.05 | 0.0774 |
Schistosoma mansoni | DNA polymerase alpha catalytic subunit | 0.0277 | 0.2479 | 0.2479 |
Echinococcus multilocularis | RNA directed DNA polymerase (reverse transcriptase) | 0.0024 | 0.0013 | 0.0042 |
Trypanosoma cruzi | UMP-CMP kinase, mitochondrial, putative | 0.0034 | 0.0115 | 0.0177 |
Brugia malayi | Pao retrotransposon peptidase family protein | 0.0024 | 0.0013 | 0.0042 |
Trichomonas vaginalis | DNA polymerase alpha catalytic subunit, putative | 0.0142 | 0.1167 | 0.382 |
Leishmania major | DNA polymerase zeta catalytic subunit, putative | 0.0063 | 0.0398 | 0.0615 |
Mycobacterium leprae | probable thymidylate kinase Tmk (dTMP KINASE) (THYMIDYLIC ACID KINASE) (TMPK) | 0.0087 | 0.0631 | 0.3897 |
Onchocerca volvulus | DNA polymerase alpha catalytic subunit homolog | 0.0347 | 0.3158 | 1 |
Trypanosoma cruzi | cysteine peptidase, clan CA, family C1, cathepsin L-like, putative | 0.0067 | 0.0438 | 0.0677 |
Trypanosoma cruzi | thymidylate kinase, putative | 0.0087 | 0.0631 | 0.0975 |
Echinococcus granulosus | RNA directed DNA polymerase reverse transcriptase | 0.0024 | 0.0013 | 0.0042 |
Giardia lamblia | Reverse transcriptase/endonuclease, putative | 0.0024 | 0.0013 | 0.0042 |
Brugia malayi | Pao retrotransposon peptidase family protein | 0.0024 | 0.0013 | 0.0042 |
Brugia malayi | RNase H family protein | 0.0101 | 0.0761 | 0.2491 |
Mycobacterium tuberculosis | Probable reductase | 0.0084 | 0.0595 | 0.1802 |
Trichomonas vaginalis | thymidylate kinase, putative | 0.0087 | 0.0631 | 0.2065 |
Trichomonas vaginalis | thymidine kinase, putative | 0.0282 | 0.253 | 0.828 |
Mycobacterium tuberculosis | NAD(P)H quinone reductase LpdA | 0.0093 | 0.0686 | 0.2077 |
Loa Loa (eye worm) | DNA polymerase epsilon catalytic subunit | 0.0063 | 0.0398 | 0.126 |
Mycobacterium tuberculosis | Probable NADH dehydrogenase Ndh | 0.0084 | 0.0595 | 0.1802 |
Plasmodium falciparum | DNA polymerase epsilon catalytic subunit A, putative | 0.0079 | 0.0551 | 0.1414 |
Brugia malayi | DNA polymerase family B, exonuclease domain containing protein | 0.0142 | 0.1167 | 0.382 |
Giardia lamblia | Reverse transcriptase/endonuclease | 0.0024 | 0.0013 | 0.0042 |
Schistosoma mansoni | scy1(yeast) protein kinase-like | 0.0024 | 0.0013 | 0.0013 |
Leishmania major | DNA polymerase I alpha catalytic subunit, putative | 0.0172 | 0.1458 | 0.2253 |
Brugia malayi | RNase H family protein | 0.0101 | 0.0761 | 0.2491 |
Schistosoma mansoni | phosphoglucomutase | 0.0101 | 0.0761 | 0.0761 |
Brugia malayi | hypothetical protein | 0.0024 | 0.0013 | 0.0042 |
Brugia malayi | Zinc knuckle family protein | 0.0024 | 0.0013 | 0.0042 |
Activity type | Activity value | Assay description | Source | Reference |
---|---|---|---|---|
Potency (functional) | 89.1251 uM | PUBCHEM_BIOASSAY: HTS for Inhibitors of HP1-beta Chromodomain Interactions with Methylated Histone Tails. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID488962] | ChEMBL. | No reference |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.