Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Echinococcus granulosus | dro:myosuppressin receptor | 0.0009 | 0.0858 | 0.1158 |
Echinococcus multilocularis | rhodopsin orphan GPCR | 0.0009 | 0.0858 | 0.1158 |
Treponema pallidum | exodeoxyribonuclease (exoA) | 0.0019 | 0.2628 | 1 |
Echinococcus granulosus | g protein linked acetylcholine receptor gar 2a | 0.0009 | 0.0858 | 0.1158 |
Brugia malayi | neuropeptide F receptor | 0.0009 | 0.0858 | 0.1158 |
Entamoeba histolytica | exodeoxyribonuclease III, putative | 0.0019 | 0.2628 | 1 |
Echinococcus granulosus | peptide allatostatin:somatostatin | 0.0009 | 0.0858 | 0.1158 |
Schistosoma mansoni | ap endonuclease | 0.0019 | 0.2628 | 0.2628 |
Echinococcus granulosus | tm gpcr rhodopsin | 0.0009 | 0.0858 | 0.1158 |
Echinococcus multilocularis | tachykinin peptides receptor 99D | 0.0009 | 0.0858 | 0.1158 |
Echinococcus multilocularis | neuropeptide receptor A26 | 0.0009 | 0.0858 | 0.1158 |
Onchocerca volvulus | 0.0009 | 0.0858 | 0.1966 | |
Brugia malayi | G-protein coupled receptor | 0.0009 | 0.0858 | 0.1158 |
Schistosoma mansoni | amine GPCR | 0.0009 | 0.0858 | 0.0858 |
Onchocerca volvulus | 0.0027 | 0.4094 | 0.9382 | |
Echinococcus multilocularis | cytoplasmic intermediate filament protein | 0.0013 | 0.1632 | 0.2203 |
Echinococcus multilocularis | tm gpcr rhodopsin gpcr rhodopsin superfamily | 0.0009 | 0.0858 | 0.1158 |
Echinococcus multilocularis | g protein coupled receptor | 0.0009 | 0.0858 | 0.1158 |
Loa Loa (eye worm) | hypothetical protein | 0.0009 | 0.0858 | 0.1158 |
Echinococcus granulosus | lamin dm0 | 0.0027 | 0.4094 | 0.5527 |
Loa Loa (eye worm) | G-protein coupled receptor | 0.0009 | 0.0858 | 0.1158 |
Echinococcus multilocularis | histone lysine N methyltransferase MLL3 | 0.0009 | 0.0891 | 0.1203 |
Loa Loa (eye worm) | cytoplasmic intermediate filament protein | 0.0014 | 0.1884 | 0.2544 |
Echinococcus granulosus | lamin | 0.0027 | 0.4094 | 0.5527 |
Echinococcus multilocularis | growth hormone secretagogue receptor type 1 | 0.0009 | 0.0858 | 0.1158 |
Brugia malayi | RE15519p | 0.0009 | 0.0858 | 0.1158 |
Echinococcus multilocularis | g protein linked acetylcholine receptor gar 2a | 0.0009 | 0.0858 | 0.1158 |
Brugia malayi | Serotonin/octopamine receptor family protein 7 | 0.0009 | 0.0858 | 0.1158 |
Echinococcus multilocularis | thyrotropin releasing hormone receptor | 0.0009 | 0.0858 | 0.1158 |
Onchocerca volvulus | 0.0009 | 0.0858 | 0.1966 | |
Loa Loa (eye worm) | gonadotropin-releasing hormone receptor 2 | 0.0009 | 0.0858 | 0.1158 |
Echinococcus multilocularis | rhodopsin orphan GPCR | 0.0009 | 0.0858 | 0.1158 |
Schistosoma mansoni | ap endonuclease | 0.0019 | 0.2628 | 0.2628 |
Loa Loa (eye worm) | hypothetical protein | 0.0009 | 0.0858 | 0.1158 |
Schistosoma mansoni | neuropeptide f receptor 76f | 0.0009 | 0.0858 | 0.0858 |
Brugia malayi | G protein-coupled receptor F59B2.13 | 0.0009 | 0.0858 | 0.1158 |
Brugia malayi | Dopamine receptor protein 2 | 0.0009 | 0.0858 | 0.1158 |
Schistosoma mansoni | rhodopsin-like orphan GPCR | 0.0009 | 0.0858 | 0.0858 |
Echinococcus multilocularis | rhodopsin orphan GPCR | 0.0009 | 0.0858 | 0.1158 |
Loa Loa (eye worm) | hypothetical protein | 0.0009 | 0.0858 | 0.1158 |
Echinococcus granulosus | neuropeptide Y receptor | 0.0009 | 0.0858 | 0.1158 |
Loa Loa (eye worm) | hypothetical protein | 0.0009 | 0.0858 | 0.1158 |
Brugia malayi | hypothetical protein | 0.0009 | 0.0858 | 0.1158 |
Brugia malayi | Serotonin receptor | 0.0009 | 0.0858 | 0.1158 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0045 | 0.7406 | 1 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0045 | 0.7406 | 0.7406 |
Echinococcus multilocularis | tm gpcr rhodopsin gpcr rhodopsin superfamily | 0.0009 | 0.0858 | 0.1158 |
Echinococcus multilocularis | rhodopsin orphan GPCR | 0.0009 | 0.0858 | 0.1158 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0006 | 0.0474 | 0.1806 |
Loa Loa (eye worm) | hypothetical protein | 0.0012 | 0.1545 | 0.2086 |
Echinococcus granulosus | tachykinin peptides receptor 99D | 0.0009 | 0.0858 | 0.1158 |
Schistosoma mansoni | rhodopsin-like orphan GPCR | 0.0009 | 0.0858 | 0.0858 |
Brugia malayi | AKH receptor | 0.0009 | 0.0858 | 0.1158 |
Echinococcus granulosus | neuropeptide FF receptor 2 | 0.0009 | 0.0858 | 0.1158 |
Brugia malayi | Dopamine receptor protein 1, putative (partial) | 0.0009 | 0.0858 | 0.1158 |
Echinococcus granulosus | growth hormone secretagogue receptor type 1 | 0.0009 | 0.0858 | 0.1158 |
Loa Loa (eye worm) | hypothetical protein | 0.0009 | 0.0858 | 0.1158 |
Loa Loa (eye worm) | hypothetical protein | 0.0012 | 0.1545 | 0.2086 |
Loa Loa (eye worm) | hypothetical protein | 0.0009 | 0.0858 | 0.1158 |
Onchocerca volvulus | 0.0009 | 0.0858 | 0.1966 | |
Brugia malayi | hypothetical protein | 0.0009 | 0.0858 | 0.1158 |
Echinococcus multilocularis | g protein coupled receptor | 0.0009 | 0.0858 | 0.1158 |
Echinococcus multilocularis | lamin dm0 | 0.0027 | 0.4094 | 0.5527 |
Echinococcus granulosus | somatostatin receptor | 0.0009 | 0.0858 | 0.1158 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0006 | 0.0474 | 0.1806 |
Schistosoma mansoni | growth hormone secretagogue receptor | 0.0009 | 0.0858 | 0.0858 |
Echinococcus multilocularis | orexin receptor type 2 | 0.0009 | 0.0858 | 0.1158 |
Echinococcus granulosus | tm gpcr rhodopsin | 0.0009 | 0.0858 | 0.1158 |
Echinococcus multilocularis | G protein coupled 5 hydroxytryptamine receptor | 0.0009 | 0.0858 | 0.1158 |
Brugia malayi | G protein-coupled receptor | 0.0009 | 0.0858 | 0.1158 |
Schistosoma mansoni | rhodopsin-like orphan GPCR | 0.0009 | 0.0858 | 0.0858 |
Schistosoma mansoni | peptide (allatostatin)-like receptor | 0.0009 | 0.0858 | 0.0858 |
Schistosoma mansoni | hypothetical protein | 0.0009 | 0.0858 | 0.0858 |
Schistosoma mansoni | neuropeptide F-like receptor | 0.0009 | 0.0858 | 0.0858 |
Echinococcus multilocularis | histone lysine N methyltransferase MLL3 | 0.0007 | 0.0584 | 0.0789 |
Echinococcus multilocularis | mixed lineage leukemia protein mll | 0.0007 | 0.0584 | 0.0789 |
Loa Loa (eye worm) | hypothetical protein | 0.0009 | 0.0858 | 0.1158 |
Schistosoma mansoni | neuropeptide receptor | 0.0009 | 0.0858 | 0.0858 |
Loa Loa (eye worm) | follicle stimulating hormone receptor | 0.0009 | 0.0858 | 0.1158 |
Echinococcus granulosus | orexin receptor type 2 | 0.0009 | 0.0858 | 0.1158 |
Schistosoma mansoni | neuropeptide F-like receptor | 0.0009 | 0.0858 | 0.0858 |
Trichomonas vaginalis | chromodomain-helicase-DNA-binding protein, putative | 0.0006 | 0.0474 | 0.1806 |
Echinococcus granulosus | rhodopsin orphan GPCR | 0.0009 | 0.0858 | 0.1158 |
Echinococcus multilocularis | dro:myosuppressin receptor | 0.0009 | 0.0858 | 0.1158 |
Echinococcus granulosus | cytoplasmic intermediate filament protein | 0.0013 | 0.1632 | 0.2203 |
Loa Loa (eye worm) | hypothetical protein | 0.0009 | 0.0858 | 0.1158 |
Loa Loa (eye worm) | hypothetical protein | 0.0009 | 0.0858 | 0.1158 |
Brugia malayi | follicle stimulating hormone receptor | 0.0009 | 0.0858 | 0.1158 |
Echinococcus multilocularis | peptide (allatostatin:somatostatin) | 0.0009 | 0.0858 | 0.1158 |
Loa Loa (eye worm) | intermediate filament tail domain-containing protein | 0.0027 | 0.4094 | 0.5527 |
Echinococcus granulosus | neuropeptide receptor | 0.0009 | 0.0858 | 0.1158 |
Onchocerca volvulus | 0.0009 | 0.0858 | 0.1966 | |
Echinococcus granulosus | neuropeptide Y receptor | 0.0009 | 0.0858 | 0.1158 |
Brugia malayi | hypothetical protein | 0.0009 | 0.0858 | 0.1158 |
Trichomonas vaginalis | chromodomain helicase DNA binding protein, putative | 0.0006 | 0.0474 | 0.1806 |
Schistosoma mansoni | histamine-responsive GPCR (AAF21638) | 0.0009 | 0.0858 | 0.0858 |
Loa Loa (eye worm) | G-protein coupled receptor | 0.0009 | 0.0858 | 0.1158 |
Trichomonas vaginalis | ap endonuclease, putative | 0.0019 | 0.2628 | 1 |
Echinococcus granulosus | tm gpcr rhodopsin | 0.0009 | 0.0858 | 0.1158 |
Schistosoma mansoni | biogenic amine (dopamine) receptor | 0.0009 | 0.0858 | 0.0858 |
Schistosoma mansoni | lamin | 0.0027 | 0.4094 | 0.4094 |
Loa Loa (eye worm) | hypothetical protein | 0.0009 | 0.0858 | 0.1158 |
Brugia malayi | hypothetical protein | 0.0009 | 0.0858 | 0.1158 |
Trichomonas vaginalis | chromodomain helicase DNA binding protein, putative | 0.0006 | 0.0474 | 0.1806 |
Toxoplasma gondii | exonuclease III APE | 0.0019 | 0.2628 | 0.2966 |
Brugia malayi | cytoplasmic intermediate filament protein | 0.0014 | 0.1884 | 0.2544 |
Loa Loa (eye worm) | hypothetical protein | 0.0013 | 0.1632 | 0.2203 |
Echinococcus multilocularis | neuropeptide FF receptor 2 | 0.0009 | 0.0858 | 0.1158 |
Onchocerca volvulus | 0.0009 | 0.0858 | 0.1966 | |
Loa Loa (eye worm) | hypothetical protein | 0.0009 | 0.0858 | 0.1158 |
Schistosoma mansoni | peptide (FMRFamide/neurokinin-3)-like receptor | 0.0009 | 0.0858 | 0.0858 |
Echinococcus multilocularis | serotonin receptor | 0.0009 | 0.0858 | 0.1158 |
Brugia malayi | G-protein coupled receptor | 0.0009 | 0.0858 | 0.1158 |
Schistosoma mansoni | opsin-like receptor | 0.0009 | 0.0858 | 0.0858 |
Echinococcus granulosus | rhodopsin orphan GPCR | 0.0009 | 0.0858 | 0.1158 |
Schistosoma mansoni | alpha-1 adrenergic receptor | 0.0009 | 0.0858 | 0.0858 |
Brugia malayi | CXXC zinc finger family protein | 0.0028 | 0.4363 | 0.5891 |
Onchocerca volvulus | 0.0027 | 0.4094 | 0.9382 | |
Brugia malayi | putative neuropeptide receptor | 0.0009 | 0.0858 | 0.1158 |
Onchocerca volvulus | 0.0009 | 0.0858 | 0.1966 | |
Schistosoma mansoni | rhodopsin-like orphan GPCR | 0.0009 | 0.0858 | 0.0858 |
Brugia malayi | Dopamine receptor | 0.0009 | 0.0858 | 0.1158 |
Wolbachia endosymbiont of Brugia malayi | exonuclease III | 0.0019 | 0.2628 | 0.5 |
Echinococcus multilocularis | alpha 1A adrenergic receptor | 0.0009 | 0.0858 | 0.1158 |
Schistosoma mansoni | adenoreceptor | 0.0009 | 0.0858 | 0.0858 |
Echinococcus multilocularis | lamin | 0.0027 | 0.4094 | 0.5527 |
Onchocerca volvulus | 0.0009 | 0.0858 | 0.1966 | |
Schistosoma mansoni | histamine h1 receptor | 0.0009 | 0.0858 | 0.0858 |
Trichomonas vaginalis | helicase, putative | 0.0006 | 0.0474 | 0.1806 |
Schistosoma mansoni | neuropeptide receptor | 0.0009 | 0.0858 | 0.0858 |
Echinococcus multilocularis | G-protein coupled receptor, putative | 0.0009 | 0.0858 | 0.1158 |
Schistosoma mansoni | peptide (FMRFamide/somatostatin)-like receptor | 0.0009 | 0.0858 | 0.0858 |
Schistosoma mansoni | biogenic amine receptor | 0.0009 | 0.0858 | 0.0858 |
Schistosoma mansoni | rhodopsin-like orphan GPCR | 0.0009 | 0.0858 | 0.0858 |
Echinococcus granulosus | hypothetical protein | 0.0009 | 0.0858 | 0.1158 |
Schistosoma mansoni | neuropeptide receptor | 0.0009 | 0.0858 | 0.0858 |
Echinococcus multilocularis | neuropeptide receptor | 0.0009 | 0.0858 | 0.1158 |
Loa Loa (eye worm) | hypothetical protein | 0.0009 | 0.0858 | 0.1158 |
Schistosoma mansoni | peptide (allatostatin/somatostatin)-like receptor | 0.0009 | 0.0858 | 0.0858 |
Echinococcus granulosus | g protein linked acetylcholine receptor gar 2a | 0.0009 | 0.0858 | 0.1158 |
Echinococcus granulosus | 7TM GPCR rhodopsin | 0.0009 | 0.0858 | 0.1158 |
Echinococcus granulosus | neuropeptides capa receptor | 0.0009 | 0.0858 | 0.1158 |
Schistosoma mansoni | lamin | 0.0027 | 0.4094 | 0.4094 |
Loa Loa (eye worm) | hypothetical protein | 0.0009 | 0.0858 | 0.1158 |
Loa Loa (eye worm) | hypothetical protein | 0.0009 | 0.0858 | 0.1158 |
Giardia lamblia | Endonuclease/Exonuclease/phosphatase | 0.0019 | 0.2628 | 1 |
Echinococcus granulosus | g-protein coupled receptor | 0.0009 | 0.0858 | 0.1158 |
Loa Loa (eye worm) | hypothetical protein | 0.0009 | 0.0858 | 0.1158 |
Schistosoma mansoni | rhodopsin-like orphan GPCR | 0.0009 | 0.0858 | 0.0858 |
Schistosoma mansoni | rhodopsin-like orphan GPCR | 0.0009 | 0.0858 | 0.0858 |
Brugia malayi | hypothetical protein | 0.0009 | 0.0858 | 0.1158 |
Echinococcus multilocularis | rhodopsin orphan GPCR | 0.0009 | 0.0858 | 0.1158 |
Loa Loa (eye worm) | hypothetical protein | 0.0009 | 0.0858 | 0.1158 |
Loa Loa (eye worm) | hypothetical protein | 0.0009 | 0.0858 | 0.1158 |
Echinococcus granulosus | DNA apurinic or apyrimidinic site lyase | 0.0019 | 0.2628 | 0.3548 |
Onchocerca volvulus | 0.0009 | 0.0858 | 0.1966 | |
Onchocerca volvulus | 0.0009 | 0.0858 | 0.1966 | |
Brugia malayi | ORL1-like opioid receptor | 0.0009 | 0.0858 | 0.1158 |
Leishmania major | apurinic/apyrimidinic endonuclease-redox protein | 0.0019 | 0.2628 | 1 |
Toxoplasma gondii | histone lysine methyltransferase SET1 | 0.0054 | 0.8861 | 1 |
Schistosoma mansoni | myosin xvIII | 0.0009 | 0.0858 | 0.0858 |
Loa Loa (eye worm) | hypothetical protein | 0.0009 | 0.0858 | 0.1158 |
Echinococcus multilocularis | neuropeptides capa receptor | 0.0009 | 0.0858 | 0.1158 |
Loa Loa (eye worm) | histone methyltransferase | 0.0009 | 0.0891 | 0.1203 |
Onchocerca volvulus | Dopamine\/Ecdysteroid receptor homolog | 0.0009 | 0.0858 | 0.1966 |
Schistosoma mansoni | biogenic amine receptor | 0.0009 | 0.0858 | 0.0858 |
Loa Loa (eye worm) | 5-hydroxytryptamine 2C receptor | 0.0009 | 0.0858 | 0.1158 |
Schistosoma mansoni | thyrotropin-releasing hormone receptor | 0.0009 | 0.0858 | 0.0858 |
Echinococcus granulosus | g protein coupled receptor | 0.0009 | 0.0858 | 0.1158 |
Brugia malayi | G-protein-linked acetylcholine receptor protein 2, putative | 0.0009 | 0.0858 | 0.1158 |
Loa Loa (eye worm) | hypothetical protein | 0.0009 | 0.0858 | 0.1158 |
Echinococcus multilocularis | g protein coupled receptor | 0.0009 | 0.0858 | 0.1158 |
Plasmodium falciparum | AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative | 0.0019 | 0.2628 | 1 |
Echinococcus multilocularis | rhodopsin orphan GPCR | 0.0009 | 0.0858 | 0.1158 |
Trichomonas vaginalis | chromodomain-helicase-DNA-binding protein, putative | 0.0006 | 0.0474 | 0.1806 |
Mycobacterium ulcerans | exodeoxyribonuclease III protein XthA | 0.0019 | 0.2628 | 0.5 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0045 | 0.7406 | 1 |
Trichomonas vaginalis | chromodomain helicase DNA binding protein, putative | 0.0006 | 0.0474 | 0.1806 |
Brugia malayi | sulfakinin receptor protein | 0.0009 | 0.0858 | 0.1158 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0006 | 0.0474 | 0.1806 |
Echinococcus granulosus | alpha 1A adrenergic receptor | 0.0009 | 0.0858 | 0.1158 |
Schistosoma mansoni | cpg binding protein | 0.003 | 0.465 | 0.465 |
Echinococcus granulosus | cpg binding protein | 0.003 | 0.465 | 0.6278 |
Echinococcus granulosus | serotonin receptor | 0.0009 | 0.0858 | 0.1158 |
Onchocerca volvulus | 0.0028 | 0.4363 | 1 | |
Loa Loa (eye worm) | hypothetical protein | 0.0009 | 0.0858 | 0.1158 |
Echinococcus multilocularis | sex peptide receptor | 0.0009 | 0.0858 | 0.1158 |
Loa Loa (eye worm) | hypothetical protein | 0.0009 | 0.0858 | 0.1158 |
Brugia malayi | Unidentified vitellogenin-linked transcript protein 6, putative | 0.0009 | 0.0858 | 0.1158 |
Brugia malayi | GTP-binding regulatory protein Gs alpha-S chain, putative | 0.0045 | 0.7406 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0009 | 0.0858 | 0.1158 |
Echinococcus granulosus | intermediate filament protein | 0.0027 | 0.4094 | 0.5527 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0045 | 0.7406 | 0.7406 |
Loa Loa (eye worm) | hypothetical protein | 0.0009 | 0.0858 | 0.1158 |
Loa Loa (eye worm) | hypothetical protein | 0.0009 | 0.0858 | 0.1158 |
Brugia malayi | hypothetical protein | 0.0009 | 0.0858 | 0.1158 |
Trypanosoma cruzi | apurinic/apyrimidinic endonuclease | 0.0019 | 0.2628 | 1 |
Onchocerca volvulus | Neuropeptide F receptor homolog | 0.0009 | 0.0858 | 0.1966 |
Loa Loa (eye worm) | intermediate filament protein | 0.0027 | 0.4094 | 0.5527 |
Plasmodium vivax | AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative | 0.0019 | 0.2628 | 1 |
Schistosoma mansoni | mixed-lineage leukemia protein mll | 0.0007 | 0.0584 | 0.0584 |
Brugia malayi | hypothetical protein | 0.0009 | 0.0858 | 0.1158 |
Schistosoma mansoni | amine GPCR | 0.0009 | 0.0858 | 0.0858 |
Schistosoma mansoni | ancient conserved domain protein 2 (cyclin m2) | 0.0009 | 0.0858 | 0.0858 |
Echinococcus granulosus | neuropeptide receptor A26 | 0.0009 | 0.0858 | 0.1158 |
Loa Loa (eye worm) | neuropeptide F receptor | 0.0009 | 0.0858 | 0.1158 |
Echinococcus granulosus | sex peptide receptor | 0.0009 | 0.0858 | 0.1158 |
Schistosoma mansoni | cpg binding protein | 0.003 | 0.465 | 0.465 |
Brugia malayi | Serotonin receptor | 0.0009 | 0.0858 | 0.1158 |
Schistosoma mansoni | hypothetical protein | 0.0009 | 0.0858 | 0.0858 |
Schistosoma mansoni | biogenic amine (5HT) receptor | 0.0009 | 0.0858 | 0.0858 |
Loa Loa (eye worm) | exodeoxyribonuclease III family protein | 0.0019 | 0.2628 | 0.3548 |
Echinococcus multilocularis | allatostatin A receptor | 0.0009 | 0.0858 | 0.1158 |
Loa Loa (eye worm) | G-protein-linked acetylcholine receptor protein 2 | 0.0009 | 0.0858 | 0.1158 |
Loa Loa (eye worm) | hypothetical protein | 0.0009 | 0.0858 | 0.1158 |
Schistosoma mansoni | rhodopsin-like orphan GPCR | 0.0009 | 0.0858 | 0.0858 |
Echinococcus granulosus | rhodopsin orphan GPCR | 0.0009 | 0.0858 | 0.1158 |
Echinococcus granulosus | fmrfamide receptor | 0.0009 | 0.0858 | 0.1158 |
Trichomonas vaginalis | chromodomain helicase DNA binding protein, putative | 0.0006 | 0.0474 | 0.1806 |
Schistosoma mansoni | biogenic amine (5HT) receptor | 0.0009 | 0.0858 | 0.0858 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0006 | 0.0474 | 0.1806 |
Echinococcus multilocularis | biogenic amine (5HT) receptor | 0.0009 | 0.0858 | 0.1158 |
Onchocerca volvulus | 0.0009 | 0.0858 | 0.1966 | |
Brugia malayi | Intermediate filament tail domain containing protein | 0.0027 | 0.4094 | 0.5527 |
Loa Loa (eye worm) | hypothetical protein | 0.0009 | 0.0858 | 0.1158 |
Loa Loa (eye worm) | hypothetical protein | 0.0009 | 0.0858 | 0.1158 |
Brugia malayi | hypothetical protein | 0.0009 | 0.0858 | 0.1158 |
Schistosoma mansoni | mixed-lineage leukemia protein mll | 0.0004 | 0.0056 | 0.0056 |
Schistosoma mansoni | neuropeptide receptor | 0.0009 | 0.0858 | 0.0858 |
Schistosoma mansoni | amine GPCR | 0.0009 | 0.0858 | 0.0858 |
Loa Loa (eye worm) | GTP-binding regulatory protein Gs alpha-S chain | 0.0045 | 0.7406 | 1 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0006 | 0.0474 | 0.1806 |
Brugia malayi | hypothetical protein | 0.0009 | 0.0858 | 0.1158 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0045 | 0.7406 | 0.7406 |
Loa Loa (eye worm) | hypothetical protein | 0.0009 | 0.0858 | 0.1158 |
Loa Loa (eye worm) | hypothetical protein | 0.0009 | 0.0858 | 0.1158 |
Brugia malayi | hypothetical protein | 0.0009 | 0.0858 | 0.1158 |
Echinococcus multilocularis | neuropeptide receptor | 0.0009 | 0.0858 | 0.1158 |
Onchocerca volvulus | 0.0009 | 0.0858 | 0.1966 | |
Brugia malayi | larval opioid receptor | 0.0009 | 0.0858 | 0.1158 |
Schistosoma mansoni | biogenic amine (dopamine) receptor | 0.0009 | 0.0858 | 0.0858 |
Echinococcus multilocularis | cpg binding protein | 0.003 | 0.465 | 0.6278 |
Echinococcus multilocularis | G protein coupled receptor 139 | 0.0009 | 0.0858 | 0.1158 |
Brugia malayi | GnHR receptor homolog | 0.0009 | 0.0858 | 0.1158 |
Loa Loa (eye worm) | hypothetical protein | 0.0009 | 0.0858 | 0.1158 |
Brugia malayi | neuropeptide F receptor | 0.0009 | 0.0858 | 0.1158 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0006 | 0.0474 | 0.1806 |
Echinococcus granulosus | histone lysine N methyltransferase MLL3 | 0.0007 | 0.0584 | 0.0789 |
Echinococcus granulosus | biogenic amine 5HT receptor | 0.0009 | 0.0858 | 0.1158 |
Echinococcus multilocularis | musashi | 0.0027 | 0.4094 | 0.5527 |
Trichomonas vaginalis | ap endonuclease, putative | 0.0019 | 0.2628 | 1 |
Brugia malayi | putative neuropeptide receptor NPR1 | 0.0009 | 0.0858 | 0.1158 |
Loa Loa (eye worm) | neuropeptide F receptor | 0.0009 | 0.0858 | 0.1158 |
Onchocerca volvulus | 0.0009 | 0.0858 | 0.1966 | |
Schistosoma mansoni | intermediate filament proteins | 0.0027 | 0.4094 | 0.4094 |
Brugia malayi | intermediate filament protein | 0.0027 | 0.4094 | 0.5527 |
Loa Loa (eye worm) | TYRA-2 protein | 0.0009 | 0.0858 | 0.1158 |
Schistosoma mansoni | biogenic amine receptor | 0.0009 | 0.0858 | 0.0858 |
Echinococcus multilocularis | g protein linked acetylcholine receptor gar 2a | 0.0009 | 0.0858 | 0.1158 |
Loa Loa (eye worm) | hypothetical protein | 0.0009 | 0.0858 | 0.1158 |
Brugia malayi | Tachykinin-like peptides receptor 99D | 0.0009 | 0.0858 | 0.1158 |
Loa Loa (eye worm) | hypothetical protein | 0.0009 | 0.0858 | 0.1158 |
Schistosoma mansoni | opsin-like receptor | 0.0009 | 0.0858 | 0.0858 |
Loa Loa (eye worm) | hypothetical protein | 0.0009 | 0.0858 | 0.1158 |
Echinococcus granulosus | G protein coupled receptor 139 | 0.0009 | 0.0858 | 0.1158 |
Loa Loa (eye worm) | hypothetical protein | 0.0009 | 0.0858 | 0.1158 |
Loa Loa (eye worm) | hypothetical protein | 0.0009 | 0.0858 | 0.1158 |
Schistosoma mansoni | amine GPCR | 0.0009 | 0.0858 | 0.0858 |
Trypanosoma brucei | apurinic/apyrimidinic endonuclease, putative | 0.0019 | 0.2628 | 1 |
Echinococcus multilocularis | g-protein coupled receptor | 0.0009 | 0.0858 | 0.1158 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0045 | 0.7406 | 1 |
Echinococcus multilocularis | neuropeptide Y receptor | 0.0009 | 0.0858 | 0.1158 |
Echinococcus multilocularis | neuropeptides capa receptor | 0.0009 | 0.0858 | 0.1158 |
Echinococcus multilocularis | neuropeptide s receptor | 0.0009 | 0.0858 | 0.1158 |
Schistosoma mansoni | peptide (FMRFamide/somatostatin)-like receptor | 0.0009 | 0.0858 | 0.0858 |
Schistosoma mansoni | opsin-like receptor | 0.0009 | 0.0858 | 0.0858 |
Loa Loa (eye worm) | hypothetical protein | 0.0009 | 0.0858 | 0.1158 |
Echinococcus granulosus | g protein coupled receptor | 0.0009 | 0.0858 | 0.1158 |
Loa Loa (eye worm) | hypothetical protein | 0.0009 | 0.0858 | 0.1158 |
Echinococcus multilocularis | rhodopsin orphan GPCR | 0.0009 | 0.0858 | 0.1158 |
Echinococcus granulosus | rhodopsin orphan GPCR | 0.0009 | 0.0858 | 0.1158 |
Mycobacterium tuberculosis | Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) | 0.0019 | 0.2628 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0009 | 0.0858 | 0.1158 |
Echinococcus multilocularis | neuropeptide Y receptor | 0.0009 | 0.0858 | 0.1158 |
Loa Loa (eye worm) | hypothetical protein | 0.0026 | 0.4007 | 0.541 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0006 | 0.0474 | 0.1806 |
Echinococcus granulosus | mixed lineage leukemia protein mll | 0.0007 | 0.0584 | 0.0789 |
Echinococcus granulosus | 7tm_1 domain containing protein | 0.0009 | 0.0858 | 0.1158 |
Onchocerca volvulus | 0.0009 | 0.0858 | 0.1966 | |
Echinococcus multilocularis | serotonin receptor | 0.0009 | 0.0858 | 0.1158 |
Brugia malayi | Dopamine receptor protein 1 | 0.0009 | 0.0858 | 0.1158 |
Schistosoma mansoni | hypothetical protein | 0.0009 | 0.0858 | 0.0858 |
Schistosoma mansoni | biogenic amine (dopamine) receptor | 0.0009 | 0.0858 | 0.0858 |
Onchocerca volvulus | 0.0009 | 0.0858 | 0.1966 | |
Loa Loa (eye worm) | hypothetical protein | 0.0027 | 0.4094 | 0.5527 |
Echinococcus granulosus | neuropeptide s receptor | 0.0009 | 0.0858 | 0.1158 |
Echinococcus granulosus | pyroglutamylated rfamide peptide receptor | 0.0009 | 0.0858 | 0.1158 |
Echinococcus granulosus | g protein coupled receptor | 0.0009 | 0.0858 | 0.1158 |
Trichomonas vaginalis | chromodomain helicase DNA binding protein, putative | 0.0006 | 0.0474 | 0.1806 |
Echinococcus multilocularis | fmrfamide receptor | 0.0009 | 0.0858 | 0.1158 |
Echinococcus multilocularis | rhodopsin orphan GPCR | 0.0009 | 0.0858 | 0.1158 |
Schistosoma mansoni | biogenic amine (octopamine/dopamine) receptor | 0.0009 | 0.0858 | 0.0858 |
Schistosoma mansoni | muscarinic acetylcholine (GAR) receptor | 0.0009 | 0.0858 | 0.0858 |
Echinococcus multilocularis | tm gpcr rhodopsin gpcr rhodopsin superfamily | 0.0009 | 0.0858 | 0.1158 |
Brugia malayi | exodeoxyribonuclease III family protein | 0.0019 | 0.2628 | 0.3548 |
Echinococcus granulosus | neuropeptides capa receptor | 0.0009 | 0.0858 | 0.1158 |
Echinococcus granulosus | thyrotropin releasing hormone receptor | 0.0009 | 0.0858 | 0.1158 |
Schistosoma mansoni | rhodopsin-like orphan GPCR | 0.0009 | 0.0858 | 0.0858 |
Echinococcus granulosus | rhodopsin orphan GPCR | 0.0009 | 0.0858 | 0.1158 |
Echinococcus multilocularis | DNA (apurinic or apyrimidinic site) lyase | 0.0019 | 0.2628 | 0.3548 |
Echinococcus multilocularis | somatostatin receptor | 0.0009 | 0.0858 | 0.1158 |
Echinococcus multilocularis | 7TM GPCR, rhodopsin | 0.0009 | 0.0858 | 0.1158 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0045 | 0.7406 | 1 |
Trichomonas vaginalis | chromodomain helicase DNA binding protein, putative | 0.0006 | 0.0474 | 0.1806 |
Brugia malayi | F/Y-rich N-terminus family protein | 0.0009 | 0.0871 | 0.1176 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0006 | 0.0474 | 0.1806 |
Onchocerca volvulus | 0.0009 | 0.0858 | 0.1966 | |
Echinococcus granulosus | rhodopsin orphan GPCR | 0.0009 | 0.0858 | 0.1158 |
Onchocerca volvulus | 0.0009 | 0.0858 | 0.1966 | |
Echinococcus multilocularis | pyroglutamylated rfamide peptide receptor | 0.0009 | 0.0858 | 0.1158 |
Loa Loa (eye worm) | hypothetical protein | 0.0009 | 0.0858 | 0.1158 |
Brugia malayi | gonadotropin-releasing hormone receptor 2 | 0.0009 | 0.0858 | 0.1158 |
Onchocerca volvulus | 0.0009 | 0.0858 | 0.1966 | |
Trypanosoma cruzi | apurinic/apyrimidinic endonuclease, putative | 0.0019 | 0.2628 | 1 |
Echinococcus granulosus | rhodopsin orphan GPCR | 0.0009 | 0.0858 | 0.1158 |
Schistosoma mansoni | hypothetical protein | 0.0009 | 0.0858 | 0.0858 |
Loa Loa (eye worm) | melatonin receptor type 1A | 0.0009 | 0.0858 | 0.1158 |
Schistosoma mansoni | cpg binding protein | 0.0028 | 0.4363 | 0.4363 |
Loa Loa (eye worm) | hypothetical protein | 0.0009 | 0.0858 | 0.1158 |
Echinococcus granulosus | neuropeptide receptor | 0.0009 | 0.0858 | 0.1158 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0006 | 0.0474 | 0.1806 |
Loa Loa (eye worm) | CXXC zinc finger family protein | 0.0028 | 0.4363 | 0.5891 |
Echinococcus granulosus | biogenic amine 5HT receptor | 0.0009 | 0.0858 | 0.1158 |
Brugia malayi | Melatonin receptor type 1A | 0.0009 | 0.0858 | 0.1158 |
Echinococcus granulosus | allatostatin A receptor | 0.0009 | 0.0858 | 0.1158 |
Loa Loa (eye worm) | hypothetical protein | 0.0009 | 0.0858 | 0.1158 |
Echinococcus multilocularis | fmrfamide receptor | 0.0009 | 0.0858 | 0.1158 |
Echinococcus granulosus | G protein coupled 5 hydroxytryptamine receptor | 0.0009 | 0.0858 | 0.1158 |
Loa Loa (eye worm) | hypothetical protein | 0.0009 | 0.0858 | 0.1158 |
Loa Loa (eye worm) | hypothetical protein | 0.0009 | 0.0858 | 0.1158 |
Loa Loa (eye worm) | hypothetical protein | 0.0009 | 0.0858 | 0.1158 |
Echinococcus granulosus | histone lysine N methyltransferase MLL3 | 0.0009 | 0.0891 | 0.1203 |
Loa Loa (eye worm) | unidentified vitellogenin-linked transcript protein 6 | 0.0009 | 0.0858 | 0.1158 |
Loa Loa (eye worm) | hypothetical protein | 0.0009 | 0.0858 | 0.1158 |
Schistosoma mansoni | amine GPCR | 0.0009 | 0.0858 | 0.0858 |
Activity type | Activity value | Assay description | Source | Reference |
---|---|---|---|---|
Potency (functional) | 26.8545 uM | PUBCHEM_BIOASSAY: qHTS profiling assay for firefly luciferase inhibitor/activator using purified enzyme and Km concentrations of substrates (counterscreen for miR-21 project). (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID2288, AID2289, AID2598, AID411] | ChEMBL. | No reference |
Potency (functional) | = 35.4813 um | PUBCHEM_BIOASSAY: qHTS Assay for Inhibitors of Human Jumonji Domain Containing 2E (JMJD2E). (Class of assay: confirmatory) | ChEMBL. | No reference |
Potency (functional) | 39.8107 uM | PubChem BioAssay. qHTS Assay for Inhibitors of the Human Apurinic/apyrimidinic Endonuclease 1 (APE1). (Class of assay: confirmatory) | ChEMBL. | No reference |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.