Detailed information for compound 130746

Basic information

Technical information
  • TDR Targets ID: 130746
  • Name: 2-hydroxynonadecane-1,2,3-tricarboxylic acid
  • MW: 416.549 | Formula: C22H40O7
  • H donors: 4 H acceptors: 7 LogP: 6.5 Rotable bonds: 20
    Rule of 5 violations (Lipinski): 1
  • SMILES: CCCCCCCCCCCCCCCCC(C(C(=O)O)(CC(=O)O)O)C(=O)O
  • InChi: 1S/C22H40O7/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-18(20(25)26)22(29,21(27)28)17-19(23)24/h18,29H,2-17H2,1H3,(H,23,24)(H,25,26)(H,27,28)
  • InChiKey: HZLCGUXUOFWCCN-UHFFFAOYSA-N  


Substructure search Similarity search

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Synonyms

  • agaric acid
  • 666-99-9
  • NCI60_019676
  • NSC 60429
  • NSC65690
  • .alpha.-Cetylcitric acid
  • 1,2,3-Nonadecanetricarboxylic acid, 2-hydroxy-
  • Agaricic acid
  • Agaricin
  • Agaricinic acid
  • Laricic acid
  • NSC 65690
  • NSC60429
  • A7384_SIGMA
  • (-)-2-Hydroxy-1,2,3-nonadecantricarbonsaeure
  • 2-Hydroxy-1,2,3-nona- decane- tricarboxylic acid
  • 2-Hydroxy-1,2,3-nonadecanetricarboxylic acid
  • 4-03-00-01284 (Beilstein Handbook Reference)
  • Agaricinsaeure
  • BRN 1729981
  • EINECS 211-566-5
  • alpha-Cetylcitric acid
  • n-Hexadecylcitric acid

Targets

Known targets for this compound

Species Target name Source Bibliographic reference
Leishmania major fructose-1,6-bisphosphate aldolase Curated by TDR Targets References
Homo sapiens glutaminase Starlite/ChEMBL No references
Homo sapiens jun proto-oncogene Starlite/ChEMBL No references
Homo sapiens nuclear factor, erythroid 2-like 2 Starlite/ChEMBL No references
Homo sapiens K(lysine) acetyltransferase 2A Starlite/ChEMBL No references
Homo sapiens polymerase (DNA directed) kappa Starlite/ChEMBL No references
Rattus norvegicus Squalene synthetase Starlite/ChEMBL No references
Homo sapiens vitamin D (1,25- dihydroxyvitamin D3) receptor Starlite/ChEMBL No references

Predicted pathogen targets for this compound

By orthology
Species Potential target Known druggable target/s Ortholog Group
Echinococcus multilocularis dna polymerase kappa Get druggable targets OG5_127393 All targets in OG5_127393
Cryptosporidium hominis histone acetyltransferase Get druggable targets OG5_127781 All targets in OG5_127781
Leishmania mexicana fructose-1,6-bisphosphate aldolase Get druggable targets OG5_127143 All targets in OG5_127143
Plasmodium vivax histone acetyltransferase GCN5, putative Get druggable targets OG5_127781 All targets in OG5_127781
Echinococcus granulosus histone acetyltransferase KAT2B Get druggable targets OG5_127781 All targets in OG5_127781
Schistosoma mansoni fructose 16-bisphosphate aldolase Get druggable targets OG5_127143 All targets in OG5_127143
Brugia malayi acetyltransferase, GNAT family protein Get druggable targets OG5_127781 All targets in OG5_127781
Trypanosoma cruzi fructose-bisphosphate aldolase, glycosomal, putative Get druggable targets OG5_127143 All targets in OG5_127143
Echinococcus multilocularis fructose bisphosphate aldolase class I Get druggable targets OG5_127143 All targets in OG5_127143
Leishmania braziliensis squalene synthase, putative Get druggable targets OG5_129470 All targets in OG5_129470
Giardia lamblia DINP protein human, muc B family Get druggable targets OG5_127393 All targets in OG5_127393
Leishmania donovani fructose-1,6-bisphosphate aldolase Get druggable targets OG5_127143 All targets in OG5_127143
Trichomonas vaginalis DNA polymerase eta, putative Get druggable targets OG5_127393 All targets in OG5_127393
Brugia malayi bZIP transcription factor family protein Get druggable targets OG5_131442 All targets in OG5_131442
Leishmania mexicana farnesyltransferase, putative Get druggable targets OG5_129470 All targets in OG5_129470
Trypanosoma cruzi DNA polymerase kappa, putative Get druggable targets OG5_127393 All targets in OG5_127393
Trypanosoma brucei DNA polymerase kappa, putative Get druggable targets OG5_127393 All targets in OG5_127393
Brugia malayi polk-prov protein Get druggable targets OG5_127393 All targets in OG5_127393
Mycobacterium tuberculosis Possible DNA-damage-inducible protein P DinP (DNA polymerase V) (pol IV 2) (DNA nucleotidyltransferase (DNA-directed)) Get druggable targets OG5_127393 All targets in OG5_127393
Brugia malayi fructose-bisphosphate aldolase 2 Get druggable targets OG5_127143 All targets in OG5_127143
Trypanosoma brucei DNA polymerase kappa, putative Get druggable targets OG5_127393 All targets in OG5_127393
Mycobacterium ulcerans DNA polymerase IV Get druggable targets OG5_127393 All targets in OG5_127393
Theileria parva histone acetyltransferase Gcn5, putative Get druggable targets OG5_127781 All targets in OG5_127781
Trypanosoma brucei DNA polymerase kappa, putative Get druggable targets OG5_127393 All targets in OG5_127393
Trypanosoma brucei gambiense fructose-bisphosphate aldolase, glycosomal putative Get druggable targets OG5_127143 All targets in OG5_127143
Cryptosporidium hominis fructose-1,6-bisphosphate aldolase Get druggable targets OG5_127143 All targets in OG5_127143
Trypanosoma brucei DNA polymerase kappa, putative Get druggable targets OG5_127393 All targets in OG5_127393
Trypanosoma brucei DNA polymerase kappa, putative Get druggable targets OG5_127393 All targets in OG5_127393
Plasmodium berghei histone acetyltransferase GCN5, putative Get druggable targets OG5_127781 All targets in OG5_127781
Plasmodium falciparum fructose-bisphosphate aldolase Get druggable targets OG5_127143 All targets in OG5_127143
Trypanosoma cruzi fructose-bisphosphate aldolase, glycosomal, putative Get druggable targets OG5_127143 All targets in OG5_127143
Leishmania donovani DNA polymerase kappa, putative Get druggable targets OG5_127393 All targets in OG5_127393
Leishmania braziliensis DNA polymerase kappa, putative Get druggable targets OG5_127393 All targets in OG5_127393
Babesia bovis fructose-1,6-bisphosphate aldolase Get druggable targets OG5_127143 All targets in OG5_127143
Neospora caninum Bromodomain containing protein, related Get druggable targets OG5_127781 All targets in OG5_127781
Schistosoma mansoni fructose 16-bisphosphate aldolase Get druggable targets OG5_127143 All targets in OG5_127143
Toxoplasma gondii histone lysine acetyltransferase GCN5-B Get druggable targets OG5_127781 All targets in OG5_127781
Trypanosoma brucei DNA polymerase IV, putative Get druggable targets OG5_127393 All targets in OG5_127393
Echinococcus multilocularis fructose 1,6 bisphosphate aldolase Get druggable targets OG5_127143 All targets in OG5_127143
Schistosoma mansoni glutaminase Get druggable targets OG5_129245 All targets in OG5_129245
Leishmania infantum DNA polymerase kappa, putative,DNA polymerase IV, putative Get druggable targets OG5_127393 All targets in OG5_127393
Echinococcus multilocularis jun protein Get druggable targets OG5_131442 All targets in OG5_131442
Plasmodium vivax fructose 1,6-bisphosphate aldolase, putative Get druggable targets OG5_127143 All targets in OG5_127143
Trichomonas vaginalis DNA polymerase IV / kappa, putative Get druggable targets OG5_127393 All targets in OG5_127393
Trypanosoma cruzi DNA polymerase kappa, putative Get druggable targets OG5_127393 All targets in OG5_127393
Leishmania infantum squalene synthase, putative Get druggable targets OG5_129470 All targets in OG5_129470
Brugia malayi glutaminase DH11.1 Get druggable targets OG5_129245 All targets in OG5_129245
Giardia lamblia Histone acetyltransferase GCN5 Get druggable targets OG5_127781 All targets in OG5_127781
Loa Loa (eye worm) fructose-bisphosphate aldolase 1 Get druggable targets OG5_127143 All targets in OG5_127143
Leishmania infantum fructose-1,6-bisphosphate aldolase Get druggable targets OG5_127143 All targets in OG5_127143
Trypanosoma brucei DNA polymerase kappa, putative Get druggable targets OG5_127393 All targets in OG5_127393
Leishmania major DNA polymerase kappa, putative Get druggable targets OG5_127393 All targets in OG5_127393
Plasmodium yoelii histone acetyltransferase GCN5-related Get druggable targets OG5_127781 All targets in OG5_127781
Babesia bovis histone acetyltransferase Get druggable targets OG5_127781 All targets in OG5_127781
Plasmodium berghei fructose-bisphosphate aldolase 2 Get druggable targets OG5_127143 All targets in OG5_127143
Neospora caninum Fructose-bisphosphate aldolase (EC 4.1.2.13), related Get druggable targets OG5_127143 All targets in OG5_127143
Trypanosoma brucei DNA polymerase kappa, putative Get druggable targets OG5_127393 All targets in OG5_127393
Echinococcus granulosus fructose 16 bisphosphate aldolase Get druggable targets OG5_127143 All targets in OG5_127143
Candida albicans bromodomain protein similar to S. cerevisiae GCN5 (YGR252W) histone acetyltransferase Get druggable targets OG5_127781 All targets in OG5_127781
Echinococcus multilocularis gcn5proteinral control of amino acid synthesis Get druggable targets OG5_127781 All targets in OG5_127781
Trichomonas vaginalis bromodomain-containing protein, putative Get druggable targets OG5_127781 All targets in OG5_127781
Echinococcus granulosus fructose 16 bisphosphate aldolase Get druggable targets OG5_127143 All targets in OG5_127143
Trypanosoma congolense DNA polymerase kappa, putative Get druggable targets OG5_127393 All targets in OG5_127393
Trypanosoma brucei gambiense DNA polymerase kappa, putative Get druggable targets OG5_127393 All targets in OG5_127393
Plasmodium yoelii Fructose-bisphosphate aldolase class-I Get druggable targets OG5_127143 All targets in OG5_127143
Trypanosoma brucei DNA polymerase kappa, putative Get druggable targets OG5_127393 All targets in OG5_127393
Candida albicans bromodomain protein similar to S. cerevisiae GCN5 (YGR252W) histone acetyltransferase Get druggable targets OG5_127781 All targets in OG5_127781
Trypanosoma brucei squalene synthase, putative Get druggable targets OG5_129470 All targets in OG5_129470
Loa Loa (eye worm) glutaminase 2 Get druggable targets OG5_129245 All targets in OG5_129245
Leishmania major squalene synthase, putative Get druggable targets OG5_129470 All targets in OG5_129470
Trypanosoma brucei DNA polymerase kappa, putative Get druggable targets OG5_127393 All targets in OG5_127393
Candida albicans squalene synthase similar to S. cerevisiae ERG9 (YHR190W) involved in ergosterol biosynthesis Get druggable targets OG5_129470 All targets in OG5_129470
Plasmodium falciparum histone acetyltransferase GCN5 Get druggable targets OG5_127781 All targets in OG5_127781
Schistosoma mansoni gcn5proteinral control of amino-acid synthesis 5-like 2 gcnl2 Get druggable targets OG5_127781 All targets in OG5_127781
Trypanosoma cruzi fructose-bisphosphate aldolase, glycosomal, putative Get druggable targets OG5_127143 All targets in OG5_127143
Cryptosporidium parvum fructose-1,6-bisphosphate aldolase Get druggable targets OG5_127143 All targets in OG5_127143
Leishmania mexicana DNA polymerase kappa, putative,DNA polymerase IV, putative Get druggable targets OG5_127393 All targets in OG5_127393
Brugia malayi fructose-bisphosphate aldolase 1 Get druggable targets OG5_127143 All targets in OG5_127143
Trypanosoma congolense squalene synthase, putative Get druggable targets OG5_129470 All targets in OG5_129470
Trypanosoma brucei gambiense DNA polymerase kappa, putative,DNA polymerase IV, putative Get druggable targets OG5_127393 All targets in OG5_127393
Trypanosoma brucei fructose-bisphosphate aldolase, glycosomal, putative Get druggable targets OG5_127143 All targets in OG5_127143
Leishmania braziliensis DNA polymerase kappa, putative,DNA polymerase IV, putative Get druggable targets OG5_127393 All targets in OG5_127393
Mycobacterium ulcerans DNA polymerase IV Get druggable targets OG5_127393 All targets in OG5_127393
Plasmodium knowlesi fructose-bisphosphate aldolase, putative Get druggable targets OG5_127143 All targets in OG5_127143
Trypanosoma brucei gambiense farnesyltransferase, putative,squalene synthase, putative Get druggable targets OG5_129470 All targets in OG5_129470
Leishmania donovani DNA polymerase kappa, putative Get druggable targets OG5_127393 All targets in OG5_127393
Echinococcus granulosus dna polymerase kappa Get druggable targets OG5_127393 All targets in OG5_127393
Echinococcus granulosus jun protein Get druggable targets OG5_131442 All targets in OG5_131442
Schistosoma japonicum ko:K01623 fructose-bisphosphate aldolase, class I [EC4.1.2.13A], putative Get druggable targets OG5_127143 All targets in OG5_127143
Trypanosoma congolense fructose-bisphosphate aldolase, glycosomal, putative Get druggable targets OG5_127143 All targets in OG5_127143
Trypanosoma brucei gambiense DNA polymerase kappa, putative Get druggable targets OG5_127393 All targets in OG5_127393
Leishmania infantum DNA polymerase kappa, putative Get druggable targets OG5_127393 All targets in OG5_127393
Leishmania braziliensis fructose-1,6-bisphosphate aldolase Get druggable targets OG5_127143 All targets in OG5_127143
Echinococcus granulosus histone acetyltransferase KAT2B Get druggable targets OG5_127781 All targets in OG5_127781
Trypanosoma brucei gambiense DNA polymerase kappa, putative Get druggable targets OG5_127393 All targets in OG5_127393
Mycobacterium tuberculosis Probable DNA polymerase IV DinX (pol IV 1) (DNA nucleotidyltransferase (DNA-directed)) Get druggable targets OG5_127393 All targets in OG5_127393
Trypanosoma brucei gambiense DNA polymerase kappa, putative,DNA polymerase IV, putative Get druggable targets OG5_127393 All targets in OG5_127393
Echinococcus multilocularis fructose 1,6 bisphosphate aldolase Get druggable targets OG5_127143 All targets in OG5_127143
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_131442 All targets in OG5_131442
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_127393 All targets in OG5_127393
Mycobacterium ulcerans glutaminase Get druggable targets OG5_129245 All targets in OG5_129245
Trypanosoma brucei DNA polymerase kappa, putative Get druggable targets OG5_127393 All targets in OG5_127393
Loa Loa (eye worm) glutaminase Get druggable targets OG5_129245 All targets in OG5_129245
Echinococcus granulosus fructose bisphosphate aldolase class I Get druggable targets OG5_127143 All targets in OG5_127143
Toxoplasma gondii fructose-bisphosphate aldolase, putative Get druggable targets OG5_127143 All targets in OG5_127143
Toxoplasma gondii fructose-1,6-bisphosphate aldolase Get druggable targets OG5_127143 All targets in OG5_127143
Neospora caninum hypothetical protein Get druggable targets OG5_127781 All targets in OG5_127781
Trypanosoma cruzi fructose-bisphosphate aldolase, glycosomal, putative Get druggable targets OG5_127143 All targets in OG5_127143
Echinococcus multilocularis fructose 1,6 bisphosphate aldolase Get druggable targets OG5_127143 All targets in OG5_127143
Trichomonas vaginalis glutaminase, putative Get druggable targets OG5_129245 All targets in OG5_129245
Theileria parva fructose-bisphosphate aldolase, putative Get druggable targets OG5_127143 All targets in OG5_127143
Trypanosoma brucei gambiense DNA polymerase kappa, putative,DNA polymerase IV, putative Get druggable targets OG5_127393 All targets in OG5_127393
Echinococcus granulosus Basic leucine zipper bZIP transcription factor Get druggable targets OG5_131442 All targets in OG5_131442
Trypanosoma brucei DNA polymerase kappa, putative Get druggable targets OG5_127393 All targets in OG5_127393
Schistosoma japonicum ko:K06062 p300/CBP-associated factor, putative Get druggable targets OG5_127781 All targets in OG5_127781
Cryptosporidium parvum GCN5 like acetylase + bromodomain Get druggable targets OG5_127781 All targets in OG5_127781
Entamoeba histolytica acetyltransferase, GNAT family Get druggable targets OG5_127781 All targets in OG5_127781
Loa Loa (eye worm) acetyltransferase Get druggable targets OG5_127781 All targets in OG5_127781
Plasmodium knowlesi histone acetyltransferase GCN5, putative Get druggable targets OG5_127781 All targets in OG5_127781
Leishmania donovani farnesyltransferase, putative Get druggable targets OG5_129470 All targets in OG5_129470
Echinococcus granulosus fructose 16 bisphosphate aldolase Get druggable targets OG5_127143 All targets in OG5_127143
Trypanosoma congolense squalene synthase, putative Get druggable targets OG5_129470 All targets in OG5_129470
Leishmania mexicana DNA polymerase kappa, putative Get druggable targets OG5_127393 All targets in OG5_127393
Leishmania major fructose-1,6-bisphosphate aldolase Get druggable targets OG5_127143 All targets in OG5_127143
Trypanosoma congolense squalene synthase, putative Get druggable targets OG5_129470 All targets in OG5_129470
Trypanosoma cruzi squalene synthase, putative Get druggable targets OG5_129470 All targets in OG5_129470
Loa Loa (eye worm) fructose-bisphosphate aldolase 2 Get druggable targets OG5_127143 All targets in OG5_127143
Toxoplasma gondii histone lysine acetyltransferase GCN5-A Get druggable targets OG5_127781 All targets in OG5_127781
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription factor Get druggable targets OG5_131442 All targets in OG5_131442
Schistosoma japonicum ko:K03511 DNA polymerase kappa subunit, putative Get druggable targets OG5_127393 All targets in OG5_127393
Trypanosoma brucei gambiense DNA polymerase kappa, putative Get druggable targets OG5_127393 All targets in OG5_127393
Trypanosoma brucei DNA polymerase kappa, putative Get druggable targets OG5_127393 All targets in OG5_127393
Trypanosoma cruzi DNA polymerase kappa, putative Get druggable targets OG5_127393 All targets in OG5_127393
Trichomonas vaginalis cat eye syndrome critical region protein 2, cscr2, putative Get druggable targets OG5_127781 All targets in OG5_127781
Leishmania major DNA polymerase kappa, putative,DNA polymerase IV, putative Get druggable targets OG5_127393 All targets in OG5_127393
Toxoplasma gondii BRCA1 C Terminus (BRCT) domain-containing protein Get druggable targets OG5_127393 All targets in OG5_127393
Trypanosoma brucei DNA polymerase kappa, putative Get druggable targets OG5_127393 All targets in OG5_127393
Trypanosoma brucei DNA polymerase IV, putative Get druggable targets OG5_127393 All targets in OG5_127393
Trypanosoma brucei DNA polymerase kappa, putative Get druggable targets OG5_127393 All targets in OG5_127393
Trypanosoma cruzi squalene synthase, putative Get druggable targets OG5_129470 All targets in OG5_129470
Trypanosoma cruzi DNA polymerase kappa, putative Get druggable targets OG5_127393 All targets in OG5_127393
Toxoplasma gondii fructose-1,6-bisphosphate aldolase Get druggable targets OG5_127143 All targets in OG5_127143
Trypanosoma brucei DNA polymerase kappa, putative Get druggable targets OG5_127393 All targets in OG5_127393
Candida albicans squalene synthase similar to S. cerevisiae ERG9 (YHR190W) involved in ergosterol biosynthesis Get druggable targets OG5_129470 All targets in OG5_129470
By sequence similarity to non orthologous known druggable targets
Species Potential target Known druggable target Length Alignment span Identity
Brugia malayi steroid hormone receptor vitamin D (1,25- dihydroxyvitamin D3) receptor 427 aa 416 aa 24.5 %
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Trichomonas vaginalis glutaminase, putative 0.033 0.0536 0.1836
Entamoeba histolytica endonuclease/exonuclease/phosphatase family protein 0.0024 0.0003 0.0000020403
Loa Loa (eye worm) hypothetical protein 0.0772 0.1306 0.2984
Plasmodium vivax plasmepsin V, putative 0.0058 0.0063 0.0485
Schistosoma mansoni hypothetical protein 0.0089 0.0117 0.0475
Trichomonas vaginalis mannose-6-phosphate isomerase, putative 0.0099 0.0134 0.0454
Trichomonas vaginalis conserved hypothetical protein 0.0047 0.0042 0.0139
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD2 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.005 0.0048 0.0338
Echinococcus multilocularis microtubule associated protein 2 0.1393 0.239 0.2388
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.16 0.2751 0.944
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.0036 0.0024 0.0076
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0032 0.0017 0.0117
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0047 0.0042 0.0139
Plasmodium falciparum ataxin-2 like protein, putative 0.0155 0.0232 1
Plasmodium falciparum plasmepsin VII 0.0058 0.0063 0.2608
Mycobacterium ulcerans dihydrolipoamide dehydrogenase, LpdB 0.0032 0.0017 0.0109
Loa Loa (eye worm) GTP-binding regulatory protein alpha chain 0.0024 0.0003 0.0004
Schistosoma mansoni fructose 16-bisphosphate aldolase 0.011 0.0152 0.0624
Loa Loa (eye worm) hypothetical protein 0.0024 0.0003 0.0004
Loa Loa (eye worm) hypothetical protein 0.0027 0.0008 0.0016
Treponema pallidum exodeoxyribonuclease (exoA) 0.012 0.017 0.0608
Echinococcus granulosus thyroid hormone receptor alpha 0.0024 0.0003 0.0001
Plasmodium falciparum dihydrolipoyl dehydrogenase, mitochondrial 0.0032 0.0017 0.0626
Schistosoma mansoni ap endonuclease 0.012 0.017 0.07
Giardia lamblia Endonuclease/Exonuclease/phosphatase 0.012 0.017 0.0608
Onchocerca volvulus 0.0036 0.0024 0.0082
Mycobacterium leprae PROBABLE GLUTAMATE-1-SEMIALDEHYDE 2,1-AMINOMUTASE HEML (GSA) (GLUTAMATE-1-SEMIALDEHYDE AMINOTRANSFERASE) (GSA-AT) 0.0024 0.0003 0.0001
Echinococcus granulosus Chromobox protein 3 0.0047 0.0042 0.0165
Leishmania major cysteine peptidase A (CPA) 0.0036 0.0024 0.017
Echinococcus multilocularis serine:threonine protein kinase PLK1 0.0105 0.0145 0.0142
Trypanosoma cruzi heat shock protein 85, putative 0.0026 0.0007 0.0032
Brugia malayi Protein-tyrosine phosphatase containing protein 0.0294 0.0473 0.1078
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0568 0.0951 0.0948
Trypanosoma brucei DNA damage repair protein, putative 0.0044 0.0037 0.0275
Echinococcus multilocularis Protein lozenge 0.0114 0.016 0.0157
Schistosoma mansoni loxhd1 0.0042 0.0034 0.0127
Onchocerca volvulus 0.026 0.0415 0.1423
Trichomonas vaginalis PIKK family atypical protein kinase 0.0044 0.0037 0.012
Schistosoma mansoni integrin alpha-ps 0.0143 0.021 0.0868
Trypanosoma brucei phosphomannose isomerase 0.0099 0.0134 0.1065
Echinococcus multilocularis muscleblind protein 1 0.0337 0.0549 0.0546
Echinococcus granulosus cathepsin d lysosomal aspartyl protease 0.0134 0.0195 0.0805
Trichomonas vaginalis heat shock protein, putative 0.0026 0.0007 0.0018
Echinococcus multilocularis jumonji domain containing protein 0.0129 0.0185 0.0182
Brugia malayi Bromodomain containing protein 0.0081 0.0103 0.0232
Plasmodium falciparum plasmepsin III 0.0058 0.0063 0.2608
Schistosoma mansoni sex comb on midleg homolog 0.0139 0.0204 0.0841
Echinococcus multilocularis suppression of tumorigenicity 18 protein 0.0159 0.0237 0.0234
Plasmodium falciparum cysteine proteinase falcipain 2a 0.0036 0.0024 0.0911
Loa Loa (eye worm) hypothetical protein 0.0094 0.0125 0.0283
Echinococcus multilocularis tyrosine protein phosphatase non receptor type 0.0294 0.0473 0.047
Echinococcus granulosus cytoplasmic intermediate filament protein 0.0091 0.012 0.0491
Trypanosoma cruzi heat shock protein 85, putative 0.0033 0.0019 0.0128
Brugia malayi hypothetical protein 0.0099 0.0134 0.0303
Echinococcus granulosus arachidonate 5 lipoxygenase 0.0178 0.0272 0.1126
Schistosoma mansoni serine/threonine protein kinase 0.0105 0.0145 0.0594
Echinococcus granulosus terminal deoxycytidyl transferase rev1 0.0141 0.0206 0.085
Schistosoma mansoni DNA polymerase eta 0.0141 0.0206 0.085
Trypanosoma cruzi hypothetical protein, conserved 0.0044 0.0037 0.0275
Brugia malayi Guanine nucleotide-binding protein alpha-6 subunit, putative 0.0024 0.0003 0.0004
Trichomonas vaginalis GTP-binding protein (O) alpha subunit, gnao, putative 0.0024 0.0003 0.0005
Brugia malayi Intermediate filament tail domain containing protein 0.019 0.0291 0.0663
Trichomonas vaginalis GTP-binding protein alpha subunit, gna, putative 0.0024 0.0003 0.0005
Plasmodium vivax hypothetical protein, conserved 0.0092 0.0122 0.0966
Brugia malayi hypothetical protein 0.0772 0.1306 0.2984
Loa Loa (eye worm) hypothetical protein 0.0052 0.0051 0.0113
Loa Loa (eye worm) hypothetical protein 0.0058 0.0063 0.014
Trypanosoma brucei DNA polymerase kappa, putative 0.0076 0.0093 0.073
Trichomonas vaginalis CAMK family protein kinase 0.0105 0.0145 0.0491
Brugia malayi Type III restriction enzyme, res subunit family protein 0.0047 0.0042 0.0094
Schistosoma mansoni integrin alpha 0.0319 0.0517 0.2153
Brugia malayi nuclear receptor NHR-88 0.0052 0.0051 0.0113
Trypanosoma cruzi phosphomannose isomerase, putative 0.0099 0.0134 0.1065
Schistosoma mansoni tar DNA-binding protein 0.045 0.0746 0.3111
Leishmania major 4-coumarate:coa ligase-like protein 0.005 0.0048 0.0363
Treponema pallidum NADH oxidase 0.0032 0.0017 0.0052
Trypanosoma brucei GTP-binding nuclear protein rtb2, putative 0.0045 0.0039 0.0291
Brugia malayi hypothetical protein 0.0027 0.0008 0.0016
Entamoeba histolytica cysteine protease, putative 0.0036 0.0024 0.0076
Schistosoma mansoni bromodomain-containing nuclear protein 1 brd1 0.0092 0.0122 0.0498
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0052 0.0051 0.0113
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.16 0.2751 1
Trichomonas vaginalis PIKK family atypical protein kinase 0.0035 0.0021 0.0067
Trypanosoma brucei DNA polymerase kappa, putative 0.0076 0.0093 0.073
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0052 0.0051 0.0113
Brugia malayi polk-prov protein 0.0076 0.0093 0.0209
Onchocerca volvulus 0.0052 0.0051 0.0174
Brugia malayi Nuclear hormone receptor family member nhr-31 0.0052 0.0051 0.0113
Leishmania major cathepsin L-like protease 0.0036 0.0024 0.017
Loa Loa (eye worm) GTP-binding nuclear protein RAN/TC4 0.0045 0.0039 0.0086
Schistosoma mansoni chromobox protein 0.0286 0.0459 0.1909
Loa Loa (eye worm) hypothetical protein 0.0052 0.0051 0.0113
Echinococcus multilocularis 3 hydroxyacyl coenzyme A dehydrogenase type 2 0.0061 0.0067 0.0064
Mycobacterium tuberculosis Conserved hypothetical protein 0.0141 0.0206 0.0251
Giardia lamblia Histone acetyltransferase GCN5 0.0047 0.0043 0.0146
Brugia malayi F/Y-rich N-terminus family protein 0.0042 0.0034 0.0074
Brugia malayi aspartic protease BmAsp-1, identical 0.0058 0.0063 0.014
Leishmania major pantothenate kinase subunit, putative 0.0026 0.0007 0.0029
Leishmania major DNA polymerase kappa, putative,DNA polymerase IV, putative 0.0149 0.022 0.1762
Trichomonas vaginalis conserved hypothetical protein 0.0047 0.0042 0.0139
Loa Loa (eye worm) hypothetical protein 0.0047 0.0042 0.0094
Onchocerca volvulus Heterochromatin protein 1 homolog 0.016 0.024 0.0824
Plasmodium vivax fructose 1,6-bisphosphate aldolase, putative 0.011 0.0152 0.1212
Schistosoma mansoni jumonji domain containing protein 0.031 0.0501 0.2087
Echinococcus multilocularis cysteine protease 0.0036 0.0024 0.0021
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0052 0.0051 0.0113
Brugia malayi G-protein alpha subunit 0.0024 0.0003 0.0004
Echinococcus multilocularis sterol regulatory element binding protein 0.0093 0.0122 0.0119
Brugia malayi MH2 domain containing protein 0.0042 0.0034 0.0075
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0052 0.0051 0.0048
Leishmania major hypothetical protein, conserved 0.0031 0.0015 0.0093
Mycobacterium ulcerans heat shock protein 90 0.0026 0.0007 0.003
Trypanosoma cruzi heat shock protein 85, putative 0.0033 0.0019 0.0128
Leishmania major heat shock protein 83-1 0.0033 0.0019 0.0128
Brugia malayi Endonuclease/Exonuclease/phosphatase family protein 0.0024 0.0003 0.0004
Mycobacterium tuberculosis Probable chaperone protein HtpG (heat shock protein) (HSP90 family protein) (high temperature protein G) 0.0026 0.0007 0.0005
Echinococcus granulosus jumonji domain containing 1A 0.0048 0.0045 0.0176
Echinococcus multilocularis dna polymerase eta 0.0141 0.0206 0.0203
Echinococcus multilocularis chromobox protein 1 0.0286 0.0459 0.0456
Loa Loa (eye worm) jmjC domain-containing protein 0.0185 0.0284 0.0646
Echinococcus granulosus microtubule associated protein 2 0.1393 0.239 1
Loa Loa (eye worm) hypothetical protein 0.0074 0.0091 0.0204
Wolbachia endosymbiont of Brugia malayi heat shock protein 90 0.0026 0.0007 0.0227
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0036 0.0024 0.0076
Leishmania major hypothetical protein, conserved 0.0094 0.0125 0.0994
Schistosoma mansoni hypothetical protein 0.0094 0.0125 0.0512
Echinococcus granulosus retinoic acid receptor rxr beta a 0.0052 0.0051 0.0199
Leishmania major heat shock protein 83-1 0.0033 0.0019 0.0128
Brugia malayi Cathepsin L-like precursor 0.0036 0.0024 0.0052
Schistosoma mansoni tar DNA-binding protein 0.045 0.0746 0.3111
Echinococcus granulosus fructose 16 bisphosphate aldolase 0.011 0.0152 0.0624
Mycobacterium tuberculosis Probable exported protein 0.0024 0.0003 0.0000034831
Echinococcus granulosus ecdysone induced protein 78C 0.0052 0.0051 0.0199
Leishmania major 2-oxoglutarate dehydrogenase, e3 component, lipoamidedehydrogenase-like protein 0.0032 0.0017 0.0117
Entamoeba histolytica heat shock protein 90, putative 0.0033 0.0019 0.0057
Trypanosoma cruzi ISWI complex protein 0.0031 0.0015 0.0093
Loa Loa (eye worm) hypothetical protein 0.0049 0.0047 0.0104
Plasmodium falciparum importin beta, putative 0.0061 0.0067 0.2786
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0024 0.0003 0.0004
Echinococcus multilocularis Niemann Pick C1 protein 0.0216 0.0337 0.0334
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0719 0.1214 0.2773
Trichomonas vaginalis bromodomain-containing protein, putative 0.0056 0.0059 0.0196
Plasmodium vivax importin-beta 2, putative 0.0061 0.0067 0.0518
Echinococcus multilocularis gcn5proteinral control of amino acid synthesis 0.018 0.0274 0.0271
Onchocerca volvulus 0.0047 0.0042 0.0146
Brugia malayi Guanine nucleotide-binding protein alpha-12 subunit, putative 0.0024 0.0003 0.0004
Entamoeba histolytica acyl-CoA synthetase, putative 0.005 0.0048 0.0162
Entamoeba histolytica sphingomyelinase C precursor, putative 0.0024 0.0003 0.0000020403
Echinococcus granulosus chromobox protein 2 0.0047 0.0042 0.0165
Mycobacterium leprae Probable Acetylornithine aminotransferase ArgD 0.0024 0.0003 0.0001
Echinococcus granulosus fructose bisphosphate aldolase class I 0.011 0.0152 0.0624
Mycobacterium tuberculosis Probable reductase 0.0214 0.0333 0.0408
Brugia malayi chromobox protein homolog 3 0.016 0.024 0.0546
Trypanosoma cruzi heat shock protein 85, putative 0.0033 0.0019 0.0128
Echinococcus multilocularis chromobox protein 1 0.0286 0.0459 0.0456
Entamoeba histolytica endonuclease/exonuclease/phosphatase domain containing protein 0.0024 0.0003 0.0000020403
Trypanosoma brucei DNA polymerase beta thumb, putative 0.0048 0.0044 0.0336
Entamoeba histolytica endonuclease/exonuclease/phosphatase family protein 0.0024 0.0003 0.0000020403
Echinococcus granulosus fructose 16 bisphosphate aldolase 0.011 0.0152 0.0624
Echinococcus granulosus tumor protein p63 0.1316 0.2256 0.9438
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.073 0.1233 0.9314
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0032 0.0017 0.0117
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.0052 0.0051 0.0199
Trypanosoma brucei unspecified product 0.0165 0.0248 0.1991
Onchocerca volvulus 0.019 0.0291 0.1
Echinococcus multilocularis nuclear receptor subfamily 1 group D 0.0027 0.0008 0.0005
Leishmania major cathepsin L-like protease 0.0036 0.0024 0.017
Loa Loa (eye worm) ctsf protein 0.0036 0.0024 0.0052
Brugia malayi Endonuclease/Exonuclease/phosphatase family protein 0.0024 0.0003 0.0004
Loa Loa (eye worm) hypothetical protein 0.0337 0.0549 0.1252
Trypanosoma brucei mitochondrial DNA polymerase beta-PAK 0.0161 0.0242 0.1943
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0027 0.0008 0.0022
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0032 0.0017 0.0117
Echinococcus granulosus L aminoadipate semialdehyde 0.0067 0.0078 0.0315
Brugia malayi hypothetical protein 0.0042 0.0034 0.0073
Trypanosoma cruzi Heat shock protein 83, putative 0.0033 0.0019 0.0128
Schistosoma mansoni rab6-interacting 0.0042 0.0034 0.0127
Echinococcus granulosus Basic leucine zipper bZIP transcription factor 0.0101 0.0138 0.0564
Loa Loa (eye worm) hypothetical protein 0.0024 0.0003 0.0004
Trypanosoma cruzi target of rapamycin kinase 3 0.0035 0.0022 0.0149
Loa Loa (eye worm) DR-78 0.0024 0.0003 0.0004
Loa Loa (eye worm) fructose-bisphosphate aldolase 2 0.011 0.0152 0.0345
Loa Loa (eye worm) transcription factor SMAD2 0.0617 0.1037 0.2369
Trypanosoma brucei dihydrolipoamide dehydrogenase, point mutation 0.0032 0.0017 0.0117
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0058 0.0063 0.0485
Trichomonas vaginalis conserved hypothetical protein 0.017 0.0257 0.0875
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.0052 0.0051 0.0048
Brugia malayi jmjC domain containing protein 0.0048 0.0045 0.01
Trichomonas vaginalis PIKK family atypical protein kinase 0.0026 0.0006 0.0015
Leishmania major importin beta-1 subunit, putative 0.0049 0.0047 0.0356
Loa Loa (eye worm) ImpB/MucB/SamB family protein 0.0141 0.0206 0.0468
Schistosoma mansoni transient receptor potential channel 4 0.0083 0.0106 0.0432
Mycobacterium tuberculosis Probable oxidoreductase 0.0237 0.0375 0.046
Leishmania major phosphomannose isomerase 0.0099 0.0134 0.1065
Loa Loa (eye worm) MH2 domain-containing protein 0.0617 0.1037 0.2369
Echinococcus multilocularis protein patched 0.0093 0.0122 0.0119
Brugia malayi CCR4 0.0024 0.0003 0.0004
Wolbachia endosymbiont of Brugia malayi exonuclease III 0.012 0.017 1
Schistosoma mansoni kinase 0.0054 0.0054 0.0215
Trichomonas vaginalis heat shock protein, putative 0.0026 0.0007 0.0018
Schistosoma mansoni Tr4/Tr2 (homologue) 0.0052 0.0051 0.0199
Trypanosoma brucei Phosphatidylinositol 3-kinase tor1 0.0044 0.0037 0.0276
Entamoeba histolytica hypothetical protein 0.0047 0.0042 0.0143
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.0052 0.0051 0.0048
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0049 0.0047 0.0154
Echinococcus multilocularis chromobox protein 2 0.0047 0.0042 0.0039
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0024 0.0003 0.0001
Leishmania major heat shock protein 83-1 0.0033 0.0019 0.0128
Brugia malayi Cytochrome P450 family protein 0.0024 0.0003 0.0004
Trichomonas vaginalis PIKK family atypical protein kinase 0.0044 0.0037 0.012
Brugia malayi nuclear receptor RXR 0.0024 0.0003 0.0004
Brugia malayi AMP-binding enzyme family protein 0.005 0.0048 0.0106
Trichomonas vaginalis chromobox protein, putative 0.0286 0.0459 0.1569
Echinococcus granulosus Mitotic checkpoint protein PRCC C terminal 0.0122 0.0174 0.0716
Trichomonas vaginalis conserved hypothetical protein 0.0113 0.0159 0.0538
Echinococcus granulosus GPCR family 2 0.0227 0.0357 0.1484
Loa Loa (eye worm) hypothetical protein 0.0024 0.0003 0.0004
Loa Loa (eye worm) PHD-finger family protein 0.0042 0.0033 0.0073
Schistosoma mansoni importin beta-1 0.0061 0.0067 0.0267
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.0052 0.0051 0.0113
Echinococcus multilocularis ecdysone induced protein 78C 0.0052 0.0051 0.0048
Schistosoma mansoni heat shock protein 0.0033 0.0019 0.0066
Schistosoma mansoni chromodomain helicase DNA binding protein 0.0047 0.0042 0.0165
Echinococcus granulosus Squalene phytoene synthase 0.0094 0.0125 0.0512
Brugia malayi MH2 domain containing protein 0.0042 0.0034 0.0075
Leishmania major heat shock protein 83-1 0.0033 0.0019 0.0128
Plasmodium vivax AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.012 0.017 0.1358
Schistosoma mansoni hypothetical protein 0.0089 0.0117 0.0475
Leishmania major DNA polymerase eta, putative 0.0141 0.0206 0.1649
Schistosoma mansoni lipoxygenase 0.0103 0.0141 0.0578
Entamoeba histolytica hypothetical protein 0.019 0.0292 0.1053
Schistosoma mansoni ap endonuclease 0.012 0.017 0.07
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.0157 0.0235 0.0535
Mycobacterium ulcerans hypothetical protein 0.0044 0.0037 0.0256
Entamoeba histolytica hypothetical protein 0.0047 0.0042 0.0143
Brugia malayi Transient-receptor-potential like protein 0.0034 0.002 0.0043
Mycobacterium ulcerans dihydrolipoamide dehydrogenase 0.0032 0.0017 0.0109
Plasmodium falciparum chromodomain-helicase-DNA-binding protein 1 homolog, putative 0.0047 0.0042 0.1715
Mycobacterium tuberculosis Probable conserved lipoprotein 0.073 0.1233 0.1521
Trichomonas vaginalis Clan AA, family A1, cathepsin D-like aspartic peptidase 0.0134 0.0195 0.0664
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0052 0.0051 0.0199
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0032 0.0017 0.0117
Leishmania major aldehyde dehydrogenase, mitochondrial precursor 0.0263 0.042 0.3391
Entamoeba histolytica Niemann-Pick C1 protein, putative 0.0216 0.0337 0.1216
Brugia malayi cytochrome P450 0.0024 0.0003 0.0004
Trichomonas vaginalis PIKK family atypical protein kinase 0.0026 0.0006 0.0014
Toxoplasma gondii NADPH-glutathione reductase 0.0032 0.0017 0.0117
Trypanosoma cruzi heat shock protein 90, putative 0.0026 0.0007 0.0032
Mycobacterium tuberculosis Probable aldehyde dehydrogenase 0.0263 0.042 0.0516
Schistosoma mansoni fructose 16-bisphosphate aldolase 0.011 0.0152 0.0624
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0052 0.0051 0.0048
Onchocerca volvulus 0.0042 0.0034 0.0115
Brugia malayi Nuclear hormone receptor E75 0.0024 0.0003 0.0004
Loa Loa (eye worm) protein-tyrosine phosphatase 0.0294 0.0473 0.1078
Trypanosoma brucei DNA polymerase kappa, putative 0.0173 0.0262 0.2104
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0248 0.0393 0.1632
Toxoplasma gondii ImpB/MucB/SamB family protein 0.0044 0.0037 0.0275
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0138 0.0201 0.1611
Trypanosoma cruzi apurinic/apyrimidinic endonuclease 0.012 0.017 0.1358
Plasmodium falciparum heat shock protein 90 0.0033 0.0019 0.0688
Loa Loa (eye worm) CHromoDomain protein family member 0.0051 0.0049 0.0109
Schistosoma mansoni ran 0.0045 0.0039 0.015
Echinococcus granulosus lipoxygenase domain containing protein 0.0042 0.0034 0.0127
Toxoplasma gondii aldehyde dehydrogenase 0.0263 0.042 0.3391
Entamoeba histolytica exodeoxyribonuclease III, putative 0.012 0.017 0.0608
Echinococcus granulosus nuclear receptor subfamily 1 group D 0.0027 0.0008 0.0022
Mycobacterium tuberculosis Possible penicillin-binding protein 0.4662 0.8089 1
Loa Loa (eye worm) glutathione reductase 0.0094 0.0124 0.0281
Echinococcus granulosus PHD finger protein rhinoceros 0.0092 0.0122 0.0498
Loa Loa (eye worm) jmjC domain-containing protein 0.0191 0.0294 0.0668
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0036 0.0024 0.0076
Schistosoma mansoni jumonji domain containing protein 0.0048 0.0045 0.0176
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0138 0.0201 0.1611
Loa Loa (eye worm) latrophilin receptor protein 2 0.0227 0.0357 0.0814
Giardia lamblia Heat shock protein HSP 90-alpha 0.0033 0.0019 0.0057
Mycobacterium leprae conserved hypothetical protein 0.073 0.1233 0.9314
Loa Loa (eye worm) cytochrome P450 family protein 0.0024 0.0003 0.0004
Trypanosoma brucei DNA polymerase kappa, putative 0.0173 0.0262 0.2104
Brugia malayi Nuclear hormone receptor-like 1 0.0027 0.0008 0.0016
Trypanosoma cruzi polo-like protein kinase, putative 0.0105 0.0145 0.1152
Trypanosoma cruzi ISWI complex protein 0.0031 0.0015 0.0093
Schistosoma mansoni niemann-pick C1 (NPC1) 0.0219 0.0343 0.1424
Trichomonas vaginalis GTP-binding protein (z) alpha subunit, gnaz, putative 0.0024 0.0003 0.0005
Trichomonas vaginalis PIKK family atypical protein kinase 0.0035 0.0021 0.0067
Echinococcus granulosus transient receptor potential gamma protein 0.0083 0.0106 0.0432
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0047 0.0042 0.0139
Trypanosoma brucei chrX additional, unordered contigs 0.0044 0.0037 0.0275
Mycobacterium tuberculosis Conserved hypothetical protein 0.018 0.0274 0.0335
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0047 0.0042 0.0139
Toxoplasma gondii phosphomannose isomerase type I protein 0.0099 0.0134 0.1065
Schistosoma mansoni endoplasmin 0.0033 0.0019 0.0066
Loa Loa (eye worm) hypothetical protein 0.0067 0.0078 0.0176
Echinococcus granulosus JmjC domain containing protein 4 0.0048 0.0045 0.0176
Trypanosoma cruzi DNA damage repair protein, putative 0.0044 0.0037 0.0275
Echinococcus multilocularis Transcription factor, JmjC domain containing protein 0.0372 0.061 0.0607
Leishmania major DNA polymerase kappa, putative 0.0044 0.0037 0.0275
Schistosoma mansoni hypothetical protein 0.0157 0.0235 0.0973
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0038 0.0027 0.0101
Schistosoma mansoni hepatocyte nuclear factor 4-alpha (hnf-4-alpha) 0.0024 0.0003 0.0001
Leishmania major 4-coumarate:coa ligase-like protein 0.005 0.0048 0.0363
Echinococcus multilocularis cysteine protease 0.0036 0.0024 0.0021
Plasmodium vivax GTP-binding nuclear protein RAN/TC4, putative 0.0045 0.0039 0.0291
Onchocerca volvulus 0.0024 0.0003 0.0011
Onchocerca volvulus 0.0036 0.0024 0.0082
Entamoeba histolytica deoxycytidyl transferase, putative 0.0141 0.0206 0.0738
Mycobacterium tuberculosis Adenosylmethionine-8-amino-7-oxononanoate aminotransferase BioA 0.0171 0.0259 0.0317
Brugia malayi dihydrolipoyl dehydrogenase, mitochondrial precursor, putative 0.0032 0.0017 0.0037
Trichomonas vaginalis CAMK family protein kinase 0.0105 0.0145 0.0491
Entamoeba histolytica acetyltransferase, GNAT family 0.0047 0.0043 0.0146
Schistosoma mansoni zinc finger protein 0.0044 0.0037 0.0142
Mycobacterium ulcerans aldehyde dehydrogenase 0.0263 0.042 0.3158
Plasmodium falciparum histone acetyltransferase GCN5 0.0047 0.0043 0.1749
Loa Loa (eye worm) hypothetical protein 0.0024 0.0003 0.0004
Brugia malayi heat shock protein 90 0.0033 0.0019 0.004
Trypanosoma cruzi DNA polymerase beta thumb, putative 0.0048 0.0044 0.0336
Mycobacterium tuberculosis Probable hydrolase 0.073 0.1233 0.1521
Leishmania major target of rapamycin (TOR) kinase 1, putative 0.0044 0.0037 0.0276
Brugia malayi M-phase phosphoprotein, mpp8 0.0047 0.0042 0.0094
Echinococcus granulosus histone acetyltransferase KAT2B 0.0056 0.0059 0.0234
Mycobacterium leprae Probable 4-aminobutyrate aminotransferase GabT (GAMMA-AMINO-N-BUTYRATE TRANSAMINASE) (GABA TRANSAMINASE) (GLUTAMATE:SUCCINIC SEM 0.0024 0.0003 0.0001
Loa Loa (eye worm) endonuclease/Exonuclease/phosphatase 0.0024 0.0003 0.0004
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0138 0.0201 0.1611
Loa Loa (eye worm) Papain cysteine protease/cathepsin propeptide inhibitor-containing protein 0.0036 0.0024 0.0052
Loa Loa (eye worm) hypothetical protein 0.0024 0.0003 0.0004
Leishmania major protein kinase, putative,polo-like protein kinase, putative 0.0105 0.0145 0.1152
Schistosoma mansoni sex comb on midleg homolog 0.0139 0.0204 0.0841
Toxoplasma gondii PHD-finger domain-containing protein 0.0092 0.0122 0.0967
Echinococcus multilocularis zinc finger protein 0.0044 0.0037 0.0034
Loa Loa (eye worm) hypothetical protein 0.0433 0.0716 0.1634
Schistosoma mansoni chromobox protein-related (chromobox 1) (heterochromatin 1) 0.0047 0.0042 0.0165
Trypanosoma brucei PHD-zinc-finger like domain containing protein, putative 0.003 0.0014 0.0085
Entamoeba histolytica endonuclease/exonuclease/phosphatase family protein 0.0024 0.0003 0.0000020403
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.0036 0.0024 0.0076
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0058 0.0063 0.025
Loa Loa (eye worm) hypothetical protein 0.0061 0.0067 0.015
Loa Loa (eye worm) hypothetical protein 0.0099 0.0133 0.0301
Giardia lamblia DINP protein human, muc B family 0.0149 0.022 0.0789
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD3 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0035 0.0022 0.0024
Schistosoma mansoni rab6-interacting 0.0042 0.0034 0.0127
Mycobacterium ulcerans glutaminase 0.033 0.0536 0.4039
Onchocerca volvulus Polycomb protein Sfmbt homolog 0.0139 0.0204 0.07
Schistosoma mansoni intermediate filament proteins 0.019 0.0291 0.1208
Trypanosoma cruzi DNA polymerase eta, putative 0.0141 0.0206 0.1649
Schistosoma mansoni tar DNA-binding protein 0.045 0.0746 0.3111
Trypanosoma cruzi PAB1-binding protein , putative 0.0155 0.0232 0.1861
Loa Loa (eye worm) TAR-binding protein 0.045 0.0746 0.1702
Trypanosoma brucei DNA polymerase kappa, putative 0.0149 0.022 0.1762
Brugia malayi cathepsin L-like precursor 0.0024 0.0003 0.0004
Schistosoma mansoni hypothetical protein 0.0871 0.148 0.6186
Echinococcus granulosus thioredoxin glutathione reductase 0.0094 0.0124 0.0507
Schistosoma mansoni hypothetical protein 0.0042 0.0034 0.0127
Onchocerca volvulus Bile acid receptor homolog 0.0052 0.0051 0.0174
Onchocerca volvulus 0.008 0.01 0.0342
Onchocerca volvulus 0.0024 0.0003 0.0012
Schistosoma mansoni hypothetical protein 0.0089 0.0117 0.0475
Trypanosoma brucei DNA polymerase kappa, putative 0.0173 0.0262 0.2104
Loa Loa (eye worm) hypothetical protein 0.0024 0.0003 0.0004
Mycobacterium ulcerans adenosylmethionine-8-amino-7-oxononanoate aminotransferase 0.0171 0.0259 0.1938
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0134 0.0195 0.0805
Leishmania major heat shock protein 83-1 0.0033 0.0019 0.0128
Loa Loa (eye worm) hypothetical protein 0.0058 0.0063 0.014
Schistosoma mansoni hypothetical protein 0.0335 0.0545 0.2271
Leishmania major heat shock protein 83-1 0.0033 0.0019 0.0128
Loa Loa (eye worm) hypothetical protein 0.0034 0.002 0.0043
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.0052 0.0051 0.0113
Schistosoma mansoni GTP-binding protein alpha subunit gna 0.0024 0.0003 0.0001
Onchocerca volvulus 0.0157 0.0235 0.0808
Schistosoma mansoni smad1 5 8 and 0.0042 0.0034 0.013
Mycobacterium leprae Probable lipase LipE 0.073 0.1233 0.9314
Schistosoma mansoni GTP-binding protein (I) alpha-1subunit gnai1 0.0024 0.0003 0.0001
Trypanosoma brucei DNA polymerase kappa, putative 0.0173 0.0262 0.2104
Brugia malayi jmjC domain containing protein 0.0372 0.061 0.1391
Brugia malayi ecdysteroid receptor 0.0052 0.0051 0.0113
Echinococcus multilocularis lysine specific demethylase 6a 0.0048 0.0045 0.0042
Echinococcus multilocularis musashi 0.019 0.0291 0.0288
Loa Loa (eye worm) hypothetical protein 0.0052 0.0051 0.0113
Mycobacterium tuberculosis Probable lipase LipE 0.073 0.1233 0.1521
Loa Loa (eye worm) phosphatidylinositol 3 0.0044 0.0037 0.0081
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.16 0.2751 0.944
Echinococcus granulosus histone acetyltransferase KAT2B 0.017 0.0258 0.1066
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0213 0.0333 0.1382
Trichomonas vaginalis GTP-binding protein (q) alpha-11 subunit, gna11, putative 0.0024 0.0003 0.0005
Brugia malayi nuclear receptor RXR 0.0027 0.0008 0.0016
Loa Loa (eye worm) hypothetical protein 0.0024 0.0003 0.0004
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0568 0.0951 0.3969
Brugia malayi photoreceptor-specific nuclear receptor 0.0052 0.0051 0.0113
Brugia malayi Kelch motif family protein 0.0099 0.0134 0.0303
Mycobacterium leprae probable mannose-6-phosphate isomerase ManA (PHOSPHOMANNOSE ISOMERASE) (PHOSPHOMANNOISOMERASE) (PMI) (PHOSPHOHEXOISOMERASE) (PHO 0.0054 0.0055 0.0391
Trichomonas vaginalis penicillin-binding protein, putative 0.073 0.1233 0.4228
Echinococcus multilocularis survival motor neuron protein 1 0.0772 0.1306 0.1304
Loa Loa (eye worm) nuclear receptor NHR-67 0.0024 0.0003 0.0004
Echinococcus multilocularis heat shock protein 90 0.0026 0.0007 0.0004
Entamoeba histolytica serine/threonine protein kinase, putative 0.0105 0.0145 0.0516
Loa Loa (eye worm) nuclear hormone receptor-like 1 0.0027 0.0008 0.0016
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0047 0.0042 0.0139
Trichomonas vaginalis PIKK family atypical protein kinase 0.0032 0.0018 0.0053
Trypanosoma cruzi DNA polymerase eta, putative 0.0044 0.0037 0.0275
Schistosoma mansoni lamin 0.019 0.0291 0.1208
Plasmodium falciparum plasmepsin I 0.0134 0.0195 0.8396
Schistosoma mansoni mannose-6-phosphate isomerase 0.0099 0.0134 0.0549
Echinococcus granulosus phd:f box containing protein 0.0048 0.0045 0.0176
Echinococcus multilocularis Chromobox protein 3 0.0047 0.0042 0.0039
Echinococcus multilocularis peregrin 0.0101 0.0138 0.0135
Schistosoma mansoni zinc finger protein 0.0024 0.0003 0.0001
Echinococcus multilocularis integrin alpha ps 0.0143 0.021 0.0207
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0047 0.0042 0.0139
Mycobacterium tuberculosis Probable esterase LipL 0.073 0.1233 0.1521
Trichomonas vaginalis chromobox protein, putative 0.0172 0.0261 0.089
Loa Loa (eye worm) nuclear receptor nhr-7B 0.0024 0.0003 0.0004
Brugia malayi Nuclear hormone receptor E75 0.0024 0.0003 0.0004
Plasmodium falciparum fructose-bisphosphate aldolase 0.011 0.0152 0.6513
Trypanosoma cruzi squalene synthase, putative 0.0303 0.0489 0.3947
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0138 0.0201 0.1611
Brugia malayi fructose-bisphosphate aldolase 1 0.011 0.0152 0.0345
Trypanosoma cruzi DNA polymerase kappa, putative 0.0173 0.0262 0.2104
Trichomonas vaginalis type IV inositol 5-phosphatase, putative 0.0024 0.0003 0.0004
Trichomonas vaginalis conserved hypothetical protein 0.016 0.024 0.0818
Plasmodium vivax thioredoxin reductase, putative 0.0094 0.0124 0.0984
Trypanosoma brucei DNA polymerase IV, putative 0.0173 0.0262 0.2104
Echinococcus granulosus transient receptor potential ion channel A 0.0076 0.0093 0.0378
Loa Loa (eye worm) hypothetical protein 0.0024 0.0003 0.0004
Trichomonas vaginalis cat eye syndrome critical region protein 2, cscr2, putative 0.0056 0.0059 0.0196
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.019 0.0292 0.1212
Echinococcus multilocularis JmjC domain containing protein 4 0.0048 0.0045 0.0042
Echinococcus granulosus guanine nucleotide binding protein subunit 0.0024 0.0003 0.0001
Brugia malayi RNA binding protein 0.045 0.0746 0.1702
Echinococcus granulosus importin subunit beta 1 0.0061 0.0067 0.0267
Loa Loa (eye worm) hypothetical protein 0.0024 0.0003 0.0004
Brugia malayi mannose-6-phosphate isomerase, class I family protein 0.0099 0.0134 0.0303
Loa Loa (eye worm) hypothetical protein 0.0037 0.0026 0.0056
Onchocerca volvulus Protein ultraspiracle homolog 0.0052 0.0051 0.0174
Brugia malayi Cytochrome P450 family protein 0.0024 0.0003 0.0004
Giardia lamblia Heat shock protein HSP 90-alpha 0.0026 0.0007 0.0014
Trypanosoma cruzi cruzipain precursor, putative 0.0138 0.0201 0.1611
Mycobacterium tuberculosis Probable lipase LipD 0.073 0.1233 0.1521
Onchocerca volvulus 0.0024 0.0003 0.0011
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.0045 0.0039 0.0291
Trypanosoma cruzi Phosphatidylinositol 3-kinase tor1 0.0044 0.0037 0.0276
Loa Loa (eye worm) helicase 0.0047 0.0042 0.0094
Echinococcus multilocularis snurportin 1 0.0649 0.1092 0.109
Loa Loa (eye worm) integrin beta-2 0.0653 0.11 0.2512
Loa Loa (eye worm) hypothetical protein 0.0491 0.0817 0.1866
Echinococcus multilocularis heat shock protein 90 0.0033 0.0019 0.0016
Schistosoma mansoni glutaminase 0.033 0.0536 0.2234
Brugia malayi guanine nucleotide-binding protein G-o protein alpha subunit 0.0024 0.0003 0.0004
Loa Loa (eye worm) hypothetical protein 0.0142 0.0209 0.0474
Toxoplasma gondii histone lysine acetyltransferase GCN5-B 0.0056 0.0059 0.0454
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.019 0.0292 0.0289
Echinococcus granulosus Ataxin 2 N terminaldomain containing protein 0.007 0.0082 0.0332
Trypanosoma cruzi fructose-bisphosphate aldolase, glycosomal, putative 0.011 0.0152 0.1212
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0036 0.0024 0.0076
Loa Loa (eye worm) hypothetical protein 0.0177 0.027 0.0613
Echinococcus multilocularis TRP (transient receptor potential) channel 0.0034 0.002 0.0017
Loa Loa (eye worm) hypothetical protein 0.0048 0.0045 0.01
Onchocerca volvulus 0.019 0.0291 0.1
Echinococcus granulosus intermediate filament protein 0.019 0.0291 0.1208
Plasmodium falciparum plasmepsin X 0.0058 0.0063 0.2608
Loa Loa (eye worm) hypothetical protein 0.016 0.024 0.0546
Onchocerca volvulus 0.0125 0.018 0.0617
Schistosoma mansoni Smad4 0.0042 0.0034 0.013
Brugia malayi beta-lactamase family protein 0.073 0.1233 0.2817
Loa Loa (eye worm) hypothetical protein 0.0037 0.0026 0.0056
Plasmodium vivax hypothetical protein, conserved 0.073 0.1233 1
Leishmania major DNA polymerase kappa, putative 0.0149 0.022 0.1762
Echinococcus multilocularis fructose bisphosphate aldolase class I 0.011 0.0152 0.0149
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.0052 0.0051 0.0199
Echinococcus multilocularis lipoxygenase domain containing protein 0.0042 0.0034 0.003
Brugia malayi Valyl-tRNA synthetase 0.0047 0.0042 0.0094
Schistosoma mansoni hypothetical protein 0.0031 0.0015 0.0048
Brugia malayi RNA, U transporter 1 0.0173 0.0262 0.0597
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0213 0.0333 0.2682
Trichomonas vaginalis importin beta-1, putative 0.0049 0.0047 0.0154
Entamoeba histolytica acyl-coA synthetase, putative 0.005 0.0048 0.0162
Mycobacterium leprae Probable fructose bisphosphate aldolase Fba 0.0782 0.1324 1
Brugia malayi hypothetical protein 0.0027 0.0008 0.0016
Mycobacterium tuberculosis NAD(P)H quinone reductase LpdA 0.0237 0.0375 0.046
Plasmodium vivax hypothetical protein, conserved 0.0047 0.0042 0.0319
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0036 0.0024 0.0076
Schistosoma mansoni cathepsin F (C01 family) 0.0036 0.0024 0.0087
Brugia malayi Cathepsin L-like precursor 0.0036 0.0024 0.0052
Trichomonas vaginalis Phospholipase C precursor, putative 0.0024 0.0003 0.0004
Mycobacterium tuberculosis NADPH-dependent mycothiol reductase Mtr 0.0094 0.0124 0.015
Brugia malayi Cathepsin L-like precursor 0.0036 0.0024 0.0052
Echinococcus granulosus cathepsin l cysteine peptidase 0.0036 0.0024 0.0087
Trichomonas vaginalis CAMK family protein kinase 0.0105 0.0145 0.0491
Brugia malayi mannose-6-phosphate isomerase, class I family protein 0.0099 0.0134 0.0303
Brugia malayi aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase 0.0067 0.0078 0.0176
Toxoplasma gondii aspartyl protease ASP3 0.0058 0.0063 0.0485
Echinococcus granulosus peregrin 0.0101 0.0138 0.0564
Leishmania major DNA damage repair protein, putative 0.0044 0.0037 0.0275
Schistosoma mansoni chromobox protein-related (chromobox 1) (heterochromatin 1) 0.0047 0.0042 0.0165
Leishmania major heat shock protein 83-1 0.0033 0.0019 0.0128
Loa Loa (eye worm) hypothetical protein 0.0047 0.0042 0.0094
Onchocerca volvulus 0.0036 0.0024 0.0082
Echinococcus granulosus cathepsin L cysteine proteinase 0.0036 0.0024 0.0087
Onchocerca volvulus Putative neutral sphingomyelinase 0.0024 0.0003 0.0011
Loa Loa (eye worm) hypothetical protein 0.005 0.0048 0.0106
Loa Loa (eye worm) fructose-bisphosphate aldolase 1 0.011 0.0152 0.0345
Trypanosoma cruzi JmjC domain, hydroxylase, putative 0.0048 0.0045 0.0342
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0227 0.0357 0.0354
Treponema pallidum fructose-bisphosphate aldolase 0.16 0.2751 1
Echinococcus granulosus FKBP12 rapamycin complex associated protein 0.0044 0.0037 0.0142
Brugia malayi ImpB/MucB/SamB family protein 0.0141 0.0206 0.0468
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0024 0.0003 0.0004
Schistosoma mansoni hypothetical protein 0.0069 0.008 0.0324
Mycobacterium ulcerans hypothetical protein 0.018 0.0274 0.205
Schistosoma mansoni nuclear receptor 0.0024 0.0003 0.0001
Brugia malayi hypothetical protein 0.0433 0.0716 0.1634
Trypanosoma brucei heat shock protein, putative 0.0033 0.0019 0.0128
Brugia malayi Cathepsin L-like precursor 0.0036 0.0024 0.0052
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0138 0.0201 0.1611
Brugia malayi MH1 domain containing protein 0.0042 0.0034 0.0075
Echinococcus multilocularis CCR4 NOT transcription complex subunit 6 0.0024 0.0003 0.0000028173
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0036 0.0024 0.0076
Mycobacterium leprae PROBABLE NADH DEHYDROGENASE NDH 0.0214 0.0333 0.25
Trypanosoma cruzi Phosphatidylinositol 3-kinase tor2 0.0044 0.0037 0.0276
Leishmania major hypothetical protein, conserved 0.0155 0.0232 0.1861
Plasmodium falciparum conserved Plasmodium protein, unknown function 0.0047 0.0042 0.1715
Echinococcus multilocularis tumor protein p63 0.1316 0.2256 0.2254
Brugia malayi Importin beta-1 subunit 0.0061 0.0067 0.015
Brugia malayi hypothetical protein 0.0155 0.0232 0.0527
Trichomonas vaginalis chromobox protein, putative 0.0047 0.0042 0.0139
Echinococcus granulosus mothers against decapentaplegic 5 0.0042 0.0034 0.013
Plasmodium vivax aspartyl protease, putative 0.0058 0.0063 0.0485
Toxoplasma gondii PHD-finger domain-containing protein 0.003 0.0014 0.0085
Mycobacterium tuberculosis Putative ferredoxin reductase 0.0214 0.0333 0.0408
Loa Loa (eye worm) doublecortin family protein 0.0042 0.0034 0.0073
Mycobacterium tuberculosis Probable NADH dehydrogenase Ndh 0.0214 0.0333 0.0408
Trypanosoma cruzi DNA damage repair protein, putative 0.0044 0.0037 0.0275
Mycobacterium tuberculosis Conserved protein 0.073 0.1233 0.1521
Schistosoma mansoni heat shock protein 0.0033 0.0019 0.0066
Loa Loa (eye worm) PHD-finger family protein 0.0092 0.0122 0.0276
Mycobacterium ulcerans L-lysine aminotransferase 0.0024 0.0003 0.0001
Trypanosoma brucei squalene synthase, putative 0.0303 0.0489 0.3947
Loa Loa (eye worm) hypothetical protein 0.025 0.0398 0.0906
Loa Loa (eye worm) hypothetical protein 0.0093 0.0122 0.0276
Echinococcus multilocularis importin subunit beta 1 0.0061 0.0067 0.0064
Trypanosoma brucei DNA polymerase kappa, putative 0.0173 0.0262 0.2104
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0052 0.0051 0.0199
Echinococcus granulosus Nuclear hormone receptor HR96 0.0024 0.0003 0.0001
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0036 0.0024 0.0076
Schistosoma mansoni hypothetical protein 0.0491 0.0817 0.3411
Brugia malayi Cathepsin L-like precursor 0.0024 0.0003 0.0004
Schistosoma mansoni GTP-binding protein (I) alpha subunit gnai 0.0024 0.0003 0.0001
Giardia lamblia NADH oxidase lateral transfer candidate 0.0032 0.0017 0.0052
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0138 0.0201 0.1611
Echinococcus granulosus endonuclease exonuclease phosphatase 0.0573 0.096 0.401
Trichomonas vaginalis conserved hypothetical protein 0.0047 0.0042 0.0139
Loa Loa (eye worm) hypothetical protein 0.0024 0.0003 0.0004
Entamoeba histolytica inositol polyphosphate 5-phosphatase, putative 0.0024 0.0003 0.0000020403
Mycobacterium ulcerans DNA polymerase IV 0.0173 0.0262 0.196
Trypanosoma brucei unspecified product 0.0097 0.013 0.1031
Loa Loa (eye worm) hypothetical protein 0.0024 0.0003 0.0004
Leishmania major mitochondrial DNA polymerase beta 0.0341 0.0555 0.4488
Loa Loa (eye worm) cytoplasmic intermediate filament protein 0.0102 0.0138 0.0312
Onchocerca volvulus Cathepsin F homolog 0.0036 0.0024 0.0082
Schistosoma mansoni protein phosphatase 2C 0.0048 0.0045 0.0176
Loa Loa (eye worm) aspartic protease BmAsp-2 0.0134 0.0195 0.0443
Trichomonas vaginalis PIKK family atypical protein kinase 0.0032 0.0018 0.0053
Echinococcus multilocularis Polycystic kidney disease protein 0.0042 0.0034 0.003
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0036 0.0024 0.0076
Echinococcus granulosus Niemann Pick C1 protein 0.0216 0.0337 0.1399
Brugia malayi Nuclear hormone receptor family member nhr-3 0.0052 0.0051 0.0113
Giardia lamblia GTP-binding nuclear protein RAN/TC4 0.0045 0.0039 0.013
Trichomonas vaginalis conserved hypothetical protein 0.0047 0.0042 0.0139
Mycobacterium ulcerans long-chain-fatty-acid--CoA ligase 0.005 0.0048 0.0338
Schistosoma mansoni nuclear receptor 0.0024 0.0003 0.0001
Schistosoma mansoni thyroid hormone receptor 0.0174 0.0264 0.1092
Brugia malayi mbt repeat family protein 0.0139 0.0204 0.0463
Schistosoma mansoni hypothetical protein 0.0227 0.0357 0.1484
Toxoplasma gondii 'chromo' (CHRromatin Organization MOdifier) domain-containing protein 0.0047 0.0042 0.0319
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.0052 0.0051 0.0199
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0058 0.0063 0.025
Loa Loa (eye worm) endoplasmin 0.0033 0.0019 0.004
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD7 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0035 0.0022 0.0024
Mycobacterium ulcerans aldehyde dehydrogenase 0.0263 0.042 0.3158
Loa Loa (eye worm) hypothetical protein 0.0088 0.0114 0.0258
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0047 0.0042 0.0139
Brugia malayi TAR-binding protein 0.045 0.0746 0.1702
Loa Loa (eye worm) hypothetical protein 0.0052 0.0051 0.0113
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0138 0.0201 0.1611
Echinococcus granulosus geminin 0.0335 0.0545 0.2271
Entamoeba histolytica FKBP-rapamycin associated protein (FRAP), putative 0.0044 0.0037 0.0123
Echinococcus multilocularis muscleblind protein 0.0337 0.0549 0.0546
Trichomonas vaginalis CAMK family protein kinase 0.0052 0.0052 0.0172
Onchocerca volvulus 0.0024 0.0003 0.0011
Trypanosoma cruzi phytoene synthase, putative 0.0094 0.0125 0.0994
Trichomonas vaginalis conserved hypothetical protein 0.0047 0.0042 0.0139
Echinococcus multilocularis integrin alpha 3 0.0245 0.0387 0.0384
Leishmania major cathepsin L-like protease 0.0036 0.0024 0.017
Schistosoma mansoni smad1 5 8 and 0.0042 0.0034 0.013
Loa Loa (eye worm) hypothetical protein 0.0077 0.0095 0.0215
Leishmania major heat shock protein 83-1 0.0033 0.0019 0.0128
Brugia malayi Nuclear hormone receptor family member nhr-1 0.0052 0.0051 0.0113
Plasmodium falciparum plasmepsin V 0.0058 0.0063 0.2608
Loa Loa (eye worm) cysteine protease 0.0036 0.0024 0.0052
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.019 0.0291 0.0663
Brugia malayi PHD-finger family protein 0.0034 0.002 0.0043
Leishmania major heat shock protein 83-1 0.0033 0.0019 0.0128
Loa Loa (eye worm) runx1 0.0114 0.016 0.0364
Entamoeba histolytica hypothetical protein 0.019 0.0292 0.1053
Entamoeba histolytica endonuclease/exonuclease/phosphatase domain containing protein 0.0024 0.0003 0.0000020403
Brugia malayi Nuclear hormone receptor family member nhr-41 0.0052 0.0051 0.0113
Trypanosoma brucei heat shock protein, putative 0.0033 0.0019 0.0128
Plasmodium vivax multidomain scavenger receptor, putative 0.0042 0.0034 0.0247
Toxoplasma gondii aspartyl protease 0.0058 0.0063 0.0485
Brugia malayi hypothetical protein 0.0024 0.0003 0.0004
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0036 0.0024 0.0052
Loa Loa (eye worm) hypothetical protein 0.0216 0.0337 0.0768
Brugia malayi guanine nucleotide-binding protein alpha-3 subunit, putative 0.0024 0.0003 0.0004
Toxoplasma gondii exonuclease III APE 0.012 0.017 0.1358
Loa Loa (eye worm) cytochrome P450 0.0024 0.0003 0.0004
Trichomonas vaginalis PIKK family atypical protein kinase 0.0032 0.0018 0.0053
Brugia malayi glutaminase DH11.1 0.033 0.0536 0.1223
Trypanosoma cruzi squalene synthase, putative 0.0303 0.0489 0.3947
Loa Loa (eye worm) follicle stimulating hormone receptor 0.2531 0.4374 1
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.073 0.1233 0.5152
Mycobacterium tuberculosis Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB 0.0214 0.0333 0.0408
Trypanosoma brucei DNA polymerase eta, putative 0.0141 0.0206 0.1649
Trichomonas vaginalis set domain proteins, putative 0.1693 0.2914 1
Trypanosoma cruzi trypanothione reductase, putative 0.0094 0.0124 0.0984
Schistosoma mansoni scm-relatedprotein containing 4 mbt domains (sfmbt) 0.0139 0.0204 0.0841
Trichomonas vaginalis CAMK family protein kinase 0.0052 0.0052 0.0172
Loa Loa (eye worm) hypothetical protein 0.0069 0.008 0.0181
Loa Loa (eye worm) hypothetical protein 0.0086 0.0111 0.0251
Plasmodium falciparum thioredoxin reductase 0.0094 0.0124 0.5288
Echinococcus granulosus endoplasmin 0.0026 0.0007 0.0017
Loa Loa (eye worm) hypothetical protein 0.0027 0.0007 0.0013
Brugia malayi nuclear hormone receptor family member nhr-6 0.0024 0.0003 0.0004
Brugia malayi Cytochrome P450 family protein 0.0024 0.0003 0.0004
Echinococcus multilocularis terminal deoxycytidyl transferase rev1 0.0141 0.0206 0.0203
Loa Loa (eye worm) hypothetical protein 0.0125 0.018 0.0408
Schistosoma mansoni GTP-binding protein (q) alpha-11 subunit gna11 0.0024 0.0003 0.0001
Brugia malayi aspartic protease BmAsp-2, identical 0.0058 0.0063 0.014
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0036 0.0024 0.0076
Mycobacterium ulcerans acyl-CoA synthetase 0.005 0.0048 0.0338
Loa Loa (eye worm) hypothetical protein 0.0141 0.0206 0.0468
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0047 0.0042 0.0139
Loa Loa (eye worm) cytochrome P450 family protein 0.0024 0.0003 0.0004
Schistosoma mansoni hypothetical protein 0.019 0.0292 0.1212
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.0045 0.0039 0.0291
Plasmodium vivax endoplasmin, putative 0.0033 0.0019 0.0128
Onchocerca volvulus 0.073 0.1233 0.4232
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.0052 0.0051 0.0199
Trichomonas vaginalis DNA polymerase IV / kappa, putative 0.0173 0.0262 0.0893
Schistosoma mansoni endoplasmin 0.0033 0.0019 0.0066
Trichomonas vaginalis conserved hypothetical protein 0.0047 0.0042 0.0139
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0568 0.0951 0.3969
Loa Loa (eye worm) hypothetical protein 0.0024 0.0003 0.0004
Mycobacterium ulcerans ornithine aminotransferase RocD1 and RocD2 0.0024 0.0003 0.0001
Brugia malayi jmjC domain containing protein 0.0048 0.0045 0.01
Echinococcus multilocularis deoxyribonuclease 1 2 0.0024 0.0003 0.0000028173
Toxoplasma gondii cathepsin CPL 0.0036 0.0024 0.017
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD2 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.005 0.0048 0.0055
Brugia malayi nuclear receptor NHR-67 0.0024 0.0003 0.0004
Leishmania major squalene synthase, putative 0.0303 0.0489 0.3947
Leishmania major heat shock protein 83-1 0.0033 0.0019 0.0128
Loa Loa (eye worm) hypothetical protein 0.0139 0.0204 0.0463
Trichomonas vaginalis Heterochromatin protein, putative 0.0047 0.0042 0.0139
Leishmania major DNA polymerase eta, putative 0.0044 0.0037 0.0275
Trypanosoma cruzi DNA polymerase kappa, putative 0.0173 0.0262 0.2104
Schistosoma mansoni cellular tumor antigen P53 0.0193 0.0297 0.123
Loa Loa (eye worm) hypothetical protein 0.0027 0.0008 0.0016
Trichomonas vaginalis PIKK family atypical protein kinase 0.0037 0.0026 0.0082
Trypanosoma brucei heat shock protein, putative 0.0033 0.0019 0.0128
Brugia malayi Papain family cysteine protease containing protein 0.0036 0.0024 0.0052
Loa Loa (eye worm) PLK/PLK1 protein kinase 0.0105 0.0145 0.0328
Echinococcus multilocularis tar DNA binding protein 0.045 0.0746 0.0743
Loa Loa (eye worm) steroid hormone receptor 0.0052 0.0051 0.0113
Loa Loa (eye worm) glutaminase 0.033 0.0536 0.1223
Echinococcus multilocularis phd:f box containing protein 0.0048 0.0045 0.0042
Echinococcus granulosus Niemann Pick C1 protein 0.0308 0.0499 0.2076
Entamoeba histolytica inositol polyphosphate-5-phosphatase, putative 0.0024 0.0003 0.0000020403
Onchocerca volvulus 0.0067 0.0078 0.0269
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0568 0.0951 0.2171
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.0052 0.0051 0.0199
Trypanosoma brucei importin beta-1 subunit, putative 0.0061 0.0067 0.0519
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD35 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0035 0.0022 0.0024
Entamoeba histolytica chromodomain-helicase-DNA-binding protein, putative 0.0047 0.0042 0.0143
Leishmania major acetoin dehydrogenase e3 component-like protein 0.0032 0.0017 0.0117
Schistosoma mansoni hypothetical protein 0.0122 0.0174 0.0716
Trichomonas vaginalis PIKK family atypical protein kinase 0.0026 0.0006 0.0015
Leishmania major hypothetical protein, conserved 0.073 0.1233 1
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription factor 0.0101 0.0138 0.0135
Trichomonas vaginalis heat shock protein, putative 0.0026 0.0007 0.0018
Mycobacterium ulcerans flavoprotein disulfide reductase 0.0032 0.0017 0.0109
Mycobacterium ulcerans fatty-acid-CoA ligase 0.005 0.0048 0.0338
Schistosoma mansoni thyroid hormone receptor 0.0174 0.0264 0.1092
Chlamydia trachomatis acylglycerophosphoethanolamine acyltransferase 0.0037 0.0026 1
Toxoplasma gondii chromodomain helicase DNA binding protein CHD1/SWI2/SNF2 0.0047 0.0042 0.0319
Echinococcus multilocularis mannose 6 phosphate isomerase 0.0099 0.0134 0.0131
Echinococcus granulosus Transcription factor JmjC domain containing protein 0.0372 0.061 0.2541
Brugia malayi beta-lactamase family protein 0.073 0.1233 0.2817
Leishmania major cathepsin L-like protease 0.0138 0.0201 0.1611
Trypanosoma brucei unspecified product 0.0097 0.013 0.1031
Trichomonas vaginalis PIKK family atypical protein kinase 0.0035 0.0021 0.0067
Loa Loa (eye worm) hypothetical protein 0.0047 0.0042 0.0094
Trypanosoma cruzi cysteine peptidase, putative 0.0138 0.0201 0.1611
Trichomonas vaginalis CAMK family protein kinase 0.0105 0.0145 0.0491
Trypanosoma cruzi polo-like protein kinase, putative 0.0105 0.0145 0.1152
Leishmania major cathepsin L-like protease 0.0138 0.0201 0.1611
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0248 0.0393 0.1632
Loa Loa (eye worm) hypothetical protein 0.073 0.1233 0.2817
Brugia malayi Pre-SET motif family protein 0.1488 0.2555 0.584
Mycobacterium tuberculosis Probable short-chain type dehydrogenase/reductase 0.0061 0.0067 0.0079
Loa Loa (eye worm) jmjC domain-containing protein 0.0048 0.0045 0.01
Brugia malayi nuclear receptor NHR-88 0.0024 0.0003 0.0004
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0058 0.0063 0.025
Brugia malayi Integrin alpha cytoplasmic region family protein 0.0241 0.0382 0.0869
Plasmodium vivax glutathione reductase, putative 0.0094 0.0124 0.0984
Echinococcus granulosus Polycystic kidney disease protein 0.0042 0.0034 0.0127
Schistosoma mansoni TGF-beta signal transducer Smad2 0.0042 0.0034 0.013
Loa Loa (eye worm) jmjC domain-containing protein 0.0048 0.0045 0.01
Brugia malayi MH2 domain containing protein 0.0617 0.1037 0.2369
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0568 0.0951 0.3969
Brugia malayi jmjC domain containing protein 0.0048 0.0045 0.01
Loa Loa (eye worm) nucleolar RNA-associated protein alpha 0.0649 0.1092 0.2495
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0138 0.0201 0.1611
Leishmania major 4-coumarate:coa ligase-like protein 0.005 0.0048 0.0363
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0052 0.0051 0.0113
Schistosoma mansoni GTP-binding protein (q) alpha-11 subunit gna11 0.0024 0.0003 0.0001
Toxoplasma gondii fructose-1,6-bisphosphate aldolase 0.011 0.0152 0.1212
Trypanosoma cruzi major cysteine proteinase, putative 0.0108 0.015 0.1193
Loa Loa (eye worm) hypothetical protein 0.019 0.0291 0.0663
Onchocerca volvulus Serine\/threonine kinase homolog 0.0105 0.0145 0.0497
Plasmodium vivax aspartyl protease, putative 0.0058 0.0063 0.0485
Trypanosoma cruzi cysteine peptidase, putative 0.0138 0.0201 0.1611
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0138 0.0201 0.1611
Loa Loa (eye worm) RNA recognition domain-containing protein domain-containing protein 0.045 0.0746 0.1702
Loa Loa (eye worm) G protein alpha subunit 3 0.0024 0.0003 0.0004
Trypanosoma brucei DNA polymerase IV, putative 0.0173 0.0262 0.2104
Brugia malayi Muscleblind-like protein 0.0337 0.0549 0.1252
Echinococcus granulosus polycomb protein SCMH1 0.0139 0.0204 0.0841
Brugia malayi Cytochrome P450 family protein 0.0132 0.0191 0.0434
Schistosoma mansoni hypothetical protein 0.0335 0.0545 0.2271
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.012 0.017 0.0386
Onchocerca volvulus 0.0193 0.0297 0.1019
Brugia malayi Cathepsin L-like precursor 0.0036 0.0024 0.0052
Loa Loa (eye worm) hypothetical protein 0.0076 0.0093 0.0209
Onchocerca volvulus 0.005 0.0048 0.0164
Echinococcus multilocularis endonuclease exonuclease phosphatase 0.0573 0.096 0.0958
Loa Loa (eye worm) hypothetical protein 0.0091 0.012 0.0272
Schistosoma mansoni jumonji/arid domain-containing protein 0.0185 0.0284 0.1176
Brugia malayi steroid hormone receptor 0.0052 0.0051 0.0113
Trypanosoma brucei phosphatidylinositol 4-kinase, putative 0.0044 0.0037 0.0276
Echinococcus granulosus guanine nucleotide binding protein subunit 0.0024 0.0003 0.0001
Leishmania major cathepsin L-like protease 0.0036 0.0024 0.017
Trichomonas vaginalis PIKK family atypical protein kinase 0.0035 0.0021 0.0067
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0032 0.0017 0.0117
Trichomonas vaginalis ap endonuclease, putative 0.012 0.017 0.0578
Onchocerca volvulus 0.1693 0.2914 1
Leishmania major heat shock protein 83-1 0.0033 0.0019 0.0128
Trichomonas vaginalis PIKK family atypical protein kinase 0.0028 0.001 0.0029
Entamoeba histolytica hypothetical protein 0.0047 0.0042 0.0143
Loa Loa (eye worm) hypothetical protein 0.0159 0.0237 0.054
Loa Loa (eye worm) acetyltransferase 0.018 0.0274 0.0624
Schistosoma mansoni ornithine--oxo-acid transaminase 0.0024 0.0003 0.0001
Plasmodium falciparum glutathione reductase 0.0094 0.0124 0.5288
Echinococcus multilocularis methyl CpG binding domain protein 2 0.0034 0.0021 0.0018
Mycobacterium tuberculosis Probable chain -fatty-acid-CoA ligase FadD13 (fatty-acyl-CoA synthetase) 0.005 0.0048 0.0055
Loa Loa (eye worm) hypothetical protein 0.0719 0.1214 0.2773
Echinococcus granulosus methyl CpG binding domain protein 2 0.0034 0.0021 0.0074
Brugia malayi conserved hypotetical protein 0.0024 0.0003 0.0004
Entamoeba histolytica chromodomain-helicase-DNA-binding protein, putative 0.0047 0.0042 0.0143
Mycobacterium tuberculosis Probable aminotransferase 0.0171 0.0259 0.0317
Schistosoma mansoni nuclear hormone receptor 0.0052 0.0051 0.0199
Mycobacterium tuberculosis Conserved protein 0.073 0.1233 0.1521
Brugia malayi Endonuclease/Exonuclease/phosphatase family protein 0.0024 0.0003 0.0004
Echinococcus granulosus serine:threonine protein kinase PLK1 0.0105 0.0145 0.0594
Toxoplasma gondii 'chromo' (CHRromatin Organization MOdifier) domain-containing protein 0.0047 0.0042 0.0319
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0058 0.0063 0.025
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0161 0.0242 0.1943
Trichomonas vaginalis type II inositol 5-phosphatase, putative 0.0024 0.0003 0.0004
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.16 0.2751 0.944
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0138 0.0201 0.1611
Onchocerca volvulus 0.0433 0.0716 0.2458
Schistosoma mansoni patched 1 0.0093 0.0122 0.05
Toxoplasma gondii BRCA1 C Terminus (BRCT) domain-containing protein 0.0052 0.0051 0.0388
Echinococcus multilocularis short transient receptor potential channel 6 0.0057 0.006 0.0057
Brugia malayi cytoplasmic intermediate filament protein 0.0102 0.0138 0.0312
Brugia malayi jmjC domain containing protein 0.0048 0.0045 0.01
Trichomonas vaginalis chromobox protein, putative 0.0172 0.0261 0.089
Brugia malayi Associated with TFs and helicases family protein 0.0047 0.0042 0.0094
Schistosoma mansoni lozenge 0.0114 0.016 0.0659
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.16 0.2751 1
Mycobacterium ulcerans long-chain fatty-acid CoA ligase 0.005 0.0048 0.0338
Echinococcus granulosus lamin 0.019 0.0291 0.1208
Echinococcus multilocularis neutral sphingomyelinase 0.0024 0.0003 0.0000028173
Trypanosoma cruzi heat shock protein 90, putative 0.0033 0.0019 0.0128
Loa Loa (eye worm) hypothetical protein 0.0047 0.0042 0.0094
Toxoplasma gondii eukaryotic aspartyl protease superfamily protein 0.0058 0.0063 0.0485
Mycobacterium ulcerans hypothetical protein 0.073 0.1233 0.9314
Loa Loa (eye worm) thioredoxin reductase 0.0094 0.0124 0.0281
Trichomonas vaginalis CAMK family protein kinase 0.0105 0.0145 0.0491
Leishmania major trypanothione reductase 0.0094 0.0124 0.0984
Trypanosoma brucei heat shock protein, putative 0.0033 0.0019 0.0128
Trypanosoma brucei PAB1-binding protein , putative 0.0155 0.0232 0.1861
Trypanosoma brucei ISWI complex protein 0.0031 0.0015 0.0093
Schistosoma mansoni cathepsin F (C01 family) 0.0036 0.0024 0.0087
Brugia malayi hypothetical protein 0.0058 0.0063 0.014
Mycobacterium ulcerans DNA polymerase IV 0.0173 0.0262 0.196
Toxoplasma gondii fructose-1,6-bisphosphate aldolase 0.011 0.0152 0.1212
Brugia malayi Integrin beta pat-3 precursor 0.0653 0.11 0.2512
Loa Loa (eye worm) hypothetical protein 0.0024 0.0003 0.0004
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.073 0.1233 0.2817
Loa Loa (eye worm) hypothetical protein 0.0024 0.0003 0.0004
Trichomonas vaginalis PIKK family atypical protein kinase 0.0032 0.0018 0.0053
Plasmodium vivax dihydrolipoyl dehydrogenase, apicoplast, putative 0.0032 0.0017 0.0117
Echinococcus granulosus suppression of tumorigenicity 18 protein 0.0159 0.0237 0.0982
Leishmania major heat shock protein 83-1 0.0033 0.0019 0.0128
Brugia malayi hypothetical protein 0.0024 0.0003 0.0004
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0048 0.0044 0.0336
Brugia malayi GTP-binding regulatory protein alpha chain - starfish, putative 0.0024 0.0003 0.0004
Trichomonas vaginalis conserved hypothetical protein 0.0113 0.0159 0.0538
Echinococcus multilocularis short transient receptor potential channel 6 0.0057 0.006 0.0057
Entamoeba histolytica chromodomain-helicase-DNA-binding protein, putative 0.0047 0.0042 0.0143
Mycobacterium tuberculosis Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras 0.0237 0.0375 0.046
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0036 0.0024 0.0076
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0248 0.0393 0.039
Plasmodium falciparum GTP-binding nuclear protein RAN/TC4 0.0045 0.0039 0.1563
Loa Loa (eye worm) hypothetical protein 0.0241 0.0382 0.0869
Loa Loa (eye worm) CCR4-NOT transcription complex subunit 6 family protein 0.0024 0.0003 0.0004
Loa Loa (eye worm) intermediate filament protein 0.019 0.0291 0.0663
Schistosoma mansoni acetyl-CoA C-acetyltransferase 0.0045 0.004 0.0154
Loa Loa (eye worm) hypothetical protein 0.0248 0.0393 0.0895
Loa Loa (eye worm) cytochrome P450 family protein 0.0132 0.0191 0.0434
Echinococcus multilocularis thioredoxin glutathione reductase 0.0094 0.0124 0.0121
Toxoplasma gondii thioredoxin reductase 0.0094 0.0124 0.0984
Brugia malayi CHD4 protein 0.0051 0.0049 0.0109
Trypanosoma brucei DNA polymerase kappa, putative 0.0105 0.0144 0.1144
Leishmania major fructose-1,6-bisphosphate aldolase 0.011 0.0152 0.1212
Trichomonas vaginalis conserved hypothetical protein 0.0047 0.0042 0.0139
Giardia lamblia Fructose-bisphosphate aldolase 0.16 0.2751 1
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0568 0.0951 0.0948
Trypanosoma cruzi fructose-bisphosphate aldolase, glycosomal, putative 0.011 0.0152 0.1212
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0036 0.0024 0.0076
Brugia malayi Eukaryotic aspartyl protease family protein 0.0058 0.0063 0.014
Loa Loa (eye worm) abnormal chemotaxis protein 14 0.0093 0.0122 0.0276
Schistosoma mansoni microtubule-associated protein tau 0.1393 0.239 1
Brugia malayi CHE-14 protein 0.0093 0.0122 0.0276
Brugia malayi hypothetical protein 0.0042 0.0034 0.0073
Echinococcus multilocularis histone acetyltransferase MYST2 0.0159 0.0237 0.0234
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.0052 0.0051 0.0113
Schistosoma mansoni integrin alpha-ps 0.0074 0.0091 0.0367
Echinococcus granulosus guanine nucleotide binding protein G protein 0.0024 0.0003 0.0001
Toxoplasma gondii pyruvate dehydrogenase complex subunit PDH-E3II 0.0032 0.0017 0.0117
Trichomonas vaginalis esterase, putative 0.073 0.1233 0.4228
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.073 0.1233 0.5152
Schistosoma mansoni memapsin-2 (A01 family) 0.0893 0.1519 0.6349
Brugia malayi jmjC domain containing protein 0.0185 0.0284 0.0646
Toxoplasma gondii histone lysine acetyltransferase GCN5-A 0.0056 0.0059 0.0454
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0058 0.0063 0.025
Echinococcus multilocularis fructose 1,6 bisphosphate aldolase 0.011 0.0152 0.0149
Onchocerca volvulus 0.073 0.1233 0.4232
Trichomonas vaginalis penicillin-binding protein, putative 0.073 0.1233 0.4228
Brugia malayi hypothetical protein 0.0058 0.0063 0.014
Loa Loa (eye worm) hypothetical protein 0.0024 0.0003 0.0004
Loa Loa (eye worm) hypothetical protein 0.0024 0.0003 0.0004
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.16 0.2751 0.944
Echinococcus multilocularis beta LACTamase domain containing family member 0.073 0.1233 0.123
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0061 0.0067 0.0481
Trypanosoma brucei hypothetical protein, conserved 0.073 0.1233 1
Loa Loa (eye worm) hypothetical protein 0.073 0.1233 0.2817
Brugia malayi PHD-finger family protein 0.0092 0.0122 0.0276
Loa Loa (eye worm) hypothetical protein 0.0088 0.0114 0.0258
Loa Loa (eye worm) hypothetical protein 0.0083 0.0106 0.024
Echinococcus multilocularis dihydrolipoamide dehydrogenase 0.0032 0.0017 0.0014
Schistosoma mansoni transient receptor potential channel 0.0083 0.0106 0.0432
Echinococcus multilocularis endoplasmin 0.0026 0.0007 0.0004
Loa Loa (eye worm) mannose-6-phosphate isomerase 0.0099 0.0134 0.0303
Loa Loa (eye worm) MH1 domain-containing protein 0.0042 0.0034 0.0075
Chlamydia trachomatis dihydrolipoyl dehydrogenase 0.0032 0.0017 0.6306
Echinococcus granulosus dihydrolipoamide dehydrogenase 0.0032 0.0017 0.006
Echinococcus multilocularis GTP binding nuclear protein Ran 0.0045 0.0039 0.0036
Onchocerca volvulus 0.0058 0.0063 0.0216
Trichomonas vaginalis acetylornithine aminotransferase, putative 0.0171 0.0259 0.0883
Echinococcus granulosus dna polymerase eta 0.0141 0.0206 0.085
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0213 0.0333 0.033
Trichomonas vaginalis carbon catabolite repressor protein, putative 0.0024 0.0003 0.0004
Brugia malayi 3-hydroxyacyl-CoA dehydrogenase type II 0.0061 0.0067 0.0149
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0047 0.0042 0.0139
Trypanosoma cruzi hypothetical protein, conserved 0.0044 0.0037 0.0275
Trichomonas vaginalis mercuric reductase, putative 0.0032 0.0017 0.0053
Mycobacterium leprae DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE 0.0237 0.0375 0.2815
Trypanosoma cruzi fructose-bisphosphate aldolase, glycosomal, putative 0.011 0.0152 0.1212
Giardia lamblia Grp94/Hsp90 0.0026 0.0007 0.0014
Onchocerca volvulus Alhambra homolog 0.0092 0.0122 0.0419
Onchocerca volvulus Heterochromatin protein 1 homolog 0.0172 0.0261 0.0896
Onchocerca volvulus 0.0024 0.0003 0.0011
Trypanosoma brucei hypothetical protein, conserved 0.0044 0.0037 0.0275
Mycobacterium ulcerans glutamate-1-semialdehyde aminotransferase 0.0024 0.0003 0.0001
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0036 0.0024 0.0076
Entamoeba histolytica endonuclease/exonuclease/phosphatase family protein 0.0024 0.0003 0.0000020403
Trichomonas vaginalis ap endonuclease, putative 0.012 0.017 0.0578
Trichomonas vaginalis D-aminoacylase, putative 0.073 0.1233 0.4228
Trypanosoma cruzi DNA polymerase beta thumb, putative 0.0048 0.0044 0.0336
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0036 0.0024 0.0076
Plasmodium falciparum plasmepsin VI 0.0134 0.0195 0.8396
Brugia malayi Latrophilin receptor protein 2 0.0227 0.0357 0.0814
Schistosoma mansoni chromodomain helicase DNA binding protein 0.0051 0.0049 0.0193
Echinococcus granulosus heat shock protein 0.0033 0.0019 0.0066
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0061 0.0067 0.0481
Schistosoma mansoni hypothetical protein 0.0227 0.0357 0.1484
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.16 0.2751 0.944
Brugia malayi SET domain containing protein 0.0055 0.0056 0.0125
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.012 0.017 0.07
Brugia malayi PHD-finger family protein 0.0054 0.0056 0.0124
Trypanosoma brucei fructose-bisphosphate aldolase, glycosomal, putative 0.011 0.0152 0.1212
Brugia malayi Guanine nucleotide-binding protein alpha-3 subunit, putative 0.0024 0.0003 0.0004
Trypanosoma brucei importin beta-1 subunit, putative 0.0061 0.0067 0.0519
Echinococcus multilocularis heat shock protein 0.0033 0.0019 0.0016
Entamoeba histolytica G protein alpha subunit, putative 0.0024 0.0003 0.0001
Mycobacterium ulcerans fructose-bisphosphate aldolase 0.0782 0.1324 1
Brugia malayi ecdysone receptor 0.0024 0.0003 0.0004
Entamoeba histolytica hypothetical protein 0.019 0.0292 0.1053
Echinococcus multilocularis expressed conserved protein 0.0203 0.0314 0.0311
Entamoeba histolytica endonuclease/exonuclease/phosphatase family protein 0.0024 0.0003 0.0000020403
Echinococcus granulosus Jumonji AT rich interactive domain 1B 0.0052 0.0052 0.0205
Echinococcus granulosus integrin alpha ps 0.0069 0.008 0.0324
Entamoeba histolytica mannose-6-phosphate isomerase, putative 0.0045 0.004 0.0135
Loa Loa (eye worm) hypothetical protein 0.073 0.1233 0.2817
Loa Loa (eye worm) hypothetical protein 0.0113 0.0159 0.036
Schistosoma mansoni hypothetical protein 0.0227 0.0357 0.1484
Plasmodium falciparum cysteine proteinase falcipain 2b 0.0036 0.0024 0.0911
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.012 0.017 0.0167
Schistosoma mansoni DNA polymerase IV / kappa 0.0044 0.0037 0.0142
Echinococcus multilocularis integrin beta 2 0.0484 0.0805 0.0802
Toxoplasma gondii ImpB/MucB/SamB family protein 0.0044 0.0037 0.0275
Schistosoma mansoni cathepsin F (C01 family) 0.0024 0.0003 0.0000094491
Trichomonas vaginalis DNA polymerase eta, putative 0.0173 0.0262 0.0893
Brugia malayi glutathione reductase 0.0094 0.0124 0.0281
Toxoplasma gondii LsmAD domain-containing protein 0.0155 0.0232 0.1861
Toxoplasma gondii aspartyl proteinase (eimepsin), putative 0.0134 0.0195 0.1562
Plasmodium falciparum phd finger protein, putative 0.0092 0.0122 0.5195
Loa Loa (eye worm) MH2 domain-containing protein 0.0042 0.0034 0.0075
Giardia lamblia DNA damage repair protein 0.0044 0.0037 0.0123
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0227 0.0357 0.1484
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.0052 0.0051 0.0113
Plasmodium vivax heterochromatin protein 1, putative 0.0047 0.0042 0.0319
Mycobacterium tuberculosis Possible DNA-damage-inducible protein P DinP (DNA polymerase V) (pol IV 2) (DNA nucleotidyltransferase (DNA-directed)) 0.0149 0.022 0.0268
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.16 0.2751 0.944
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0052 0.0051 0.0113
Plasmodium vivax vivapain-2 0.0036 0.0024 0.017
Brugia malayi guanine nucleotide-binding protein G(o), alpha subunit, putative 0.0024 0.0003 0.0004
Trichomonas vaginalis ran, putative 0.0045 0.0039 0.0127
Loa Loa (eye worm) hypothetical protein 0.0176 0.0268 0.0609
Schistosoma mansoni smad1 5 8 and 0.0042 0.0034 0.013
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0047 0.0042 0.0139
Echinococcus granulosus mannose 6 phosphate isomerase 0.0099 0.0134 0.0549
Toxoplasma gondii histone lysine demethylase JMJD6a 0.0048 0.0045 0.0342
Loa Loa (eye worm) hypothetical protein 0.0177 0.0269 0.0613
Schistosoma mansoni GTP-binding protein alpha subunit 0.0024 0.0003 0.0001
Schistosoma mansoni phosphatidylserine receptor 0.0048 0.0045 0.0176
Brugia malayi exodeoxyribonuclease III family protein 0.012 0.017 0.0386
Plasmodium vivax ataxin-2 like protein, putative 0.0155 0.0232 0.186
Loa Loa (eye worm) 3-hydroxyacyl-CoA dehydrogenase type II 0.0053 0.0053 0.0118
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0036 0.0024 0.0076
Brugia malayi Endoplasmin precursor 0.0033 0.0019 0.004
Trypanosoma brucei heat shock protein 90, putative 0.0033 0.0019 0.0128
Toxoplasma gondii HEAT repeat-containing protein 0.0061 0.0067 0.0519
Loa Loa (eye worm) hypothetical protein 0.0027 0.0008 0.0016
Echinococcus granulosus histone acetyltransferase MYST2 0.0159 0.0237 0.0982
Entamoeba histolytica endonuclease/exonuclease/phosphatase family protein 0.0024 0.0003 0.0000020403
Trichomonas vaginalis GTP-binding protein alpha subunit, gna, putative 0.0024 0.0003 0.0005
Echinococcus multilocularis FTZ F1 alpha 0.0052 0.0051 0.0048
Echinococcus multilocularis protein dispatched 1 0.0106 0.0145 0.0142
Trichomonas vaginalis PIKK family atypical protein kinase 0.0032 0.0018 0.0053
Brugia malayi Nuclear hormone receptor family member nhr-14 0.0052 0.0051 0.0113
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.073 0.1233 0.1521
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD5 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0035 0.0022 0.0024
Echinococcus multilocularis fructose 1,6 bisphosphate aldolase 0.011 0.0152 0.0149
Plasmodium vivax histone acetyltransferase GCN5, putative 0.0056 0.0059 0.0454
Loa Loa (eye worm) hypothetical protein 0.009 0.0118 0.0266
Plasmodium falciparum plasmepsin IV 0.0134 0.0195 0.8396
Plasmodium vivax mannose-6-phosphate isomerase, putative 0.0099 0.0134 0.1064
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.073 0.1233 0.2817
Trichomonas vaginalis carbon catabolite repressor protein, putative 0.0024 0.0003 0.0004
Plasmodium falciparum dihydrolipoyl dehydrogenase, apicoplast 0.0032 0.0017 0.0626
Brugia malayi 4-aminobutyrate aminotransferase, mitochondrial precursor 0.0024 0.0003 0.0004
Loa Loa (eye worm) hypothetical protein 0.0155 0.0232 0.0527
Echinococcus granulosus TGF beta signal transducer SmadC 0.0042 0.0034 0.013
Brugia malayi Nuclear hormone receptor-like 1 0.0052 0.0051 0.0113
Loa Loa (eye worm) hypothetical protein 0.0052 0.0051 0.0113
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.0072 0.0087 0.0351
Echinococcus multilocularis integrin alpha ps 0.0069 0.008 0.0077
Trypanosoma cruzi JmjC domain, hydroxylase, putative 0.0048 0.0045 0.0342
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0568 0.0951 0.3969
Plasmodium falciparum acyl-CoA synthetase 0.0037 0.0026 0.0989
Echinococcus multilocularis smad 0.0042 0.0034 0.0031
Trichomonas vaginalis chromobox protein, putative 0.0047 0.0042 0.0139
Echinococcus granulosus jun protein 0.0101 0.0138 0.0564
Toxoplasma gondii WD domain, G-beta repeat-containing protein 0.003 0.0014 0.0085
Toxoplasma gondii hypothetical protein 0.0055 0.0057 0.0436
Loa Loa (eye worm) hypothetical protein 0.0024 0.0003 0.0004
Entamoeba histolytica phosphomannose isomerase, putative 0.0099 0.0134 0.0477
Echinococcus multilocularis lamin dm0 0.019 0.0291 0.0288
Echinococcus multilocularis TGF beta signal transducer SmadC 0.0042 0.0034 0.0031
Entamoeba histolytica acyl-CoA synthetase, putative 0.005 0.0048 0.0162
Echinococcus multilocularis cathepsin l cysteine peptidase 0.0036 0.0024 0.0021
Plasmodium vivax aspartyl proteinase, putative 0.0134 0.0195 0.1562
Echinococcus multilocularis Mitotic checkpoint protein PRCC, C terminal 0.0122 0.0174 0.0171
Echinococcus multilocularis synaptojanin 1 0.0024 0.0003 0.0000028173
Onchocerca volvulus 0.0036 0.0024 0.0082
Loa Loa (eye worm) hypothetical protein 0.0186 0.0285 0.0649
Leishmania major cathepsin L-like protease 0.0138 0.0201 0.1611
Plasmodium falciparum ornithine aminotransferase 0.0024 0.0003 0.0007
Loa Loa (eye worm) hypothetical protein 0.0052 0.0051 0.0113
Loa Loa (eye worm) mannose-6-phosphate isomerase 0.0099 0.0134 0.0303
Plasmodium falciparum cysteine proteinase falcipain 3 0.0036 0.0024 0.0911
Leishmania major mitochondrial DNA polymerase beta-PAK, putative 0.0161 0.0242 0.1943
Schistosoma mansoni cathepsin D (A01 family) 0.0328 0.0533 0.222
Schistosoma mansoni lipoxygenase 0.0178 0.0272 0.1126
Loa Loa (eye worm) hypothetical protein 0.0034 0.002 0.0043
Loa Loa (eye worm) hypothetical protein 0.005 0.0048 0.0106
Brugia malayi intermediate filament protein 0.019 0.0291 0.0663
Plasmodium falciparum LCCL domain-containing protein 0.0042 0.0034 0.1329
Brugia malayi fructose-bisphosphate aldolase 2 0.011 0.0152 0.0345
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.0052 0.0051 0.0174
Onchocerca volvulus 0.0047 0.0042 0.0146
Schistosoma mansoni transient receptor potential channel 0.0057 0.006 0.0238
Loa Loa (eye worm) hypothetical protein 0.0092 0.0122 0.0276
Onchocerca volvulus NADH dehydrogenase (ubiquinone) complex I, assembly factor 6 homolog 0.0094 0.0125 0.043
Trypanosoma cruzi importin beta-1 subunit, putative 0.0049 0.0047 0.0356
Schistosoma mansoni GTP-binding protein (I) alpha-1subunit gnai1 0.0024 0.0003 0.0001
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0032 0.0017 0.0117
Wolbachia endosymbiont of Brugia malayi dihydrolipoamide dehydrogenase E3 component 0.0032 0.0017 0.085
Brugia malayi RNA recognition motif domain containing protein 0.045 0.0746 0.1702
Mycobacterium ulcerans phytoene synthase, CrtB 0.0094 0.0125 0.0926
Loa Loa (eye worm) aspartyl protease 6 0.0058 0.0063 0.014
Onchocerca volvulus 0.0042 0.0034 0.0115
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0032 0.0017 0.0117
Echinococcus multilocularis transient receptor potential gamma protein 0.0083 0.0106 0.0103
Giardia lamblia Kinase, PLK 0.0105 0.0145 0.0516
Trichomonas vaginalis G protein (olf) alpha subunit, gnal, putative 0.0024 0.0003 0.0005
Echinococcus granulosus dna polymerase kappa 0.0173 0.0262 0.1084
Echinococcus multilocularis FKBP12 rapamycin complex associated protein 0.0044 0.0037 0.0034
Loa Loa (eye worm) hypothetical protein 0.0042 0.0034 0.0073
Brugia malayi guanine nucleotide-binding protein alpha-7 subunit, putative 0.0024 0.0003 0.0004
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.0052 0.0051 0.0113
Echinococcus multilocularis geminin 0.0335 0.0545 0.0542
Plasmodium vivax aspartyl proteinase, putative 0.0058 0.0063 0.0485
Echinococcus multilocularis PHD finger protein rhinoceros 0.0092 0.0122 0.0119
Echinococcus multilocularis fetal alzheimer antigen, falz 0.0045 0.004 0.0037
Toxoplasma gondii heat shock protein 90, putative 0.0033 0.0019 0.0128
Schistosoma mansoni rab geranylgeranyl transferase alpha subunit 0.0141 0.0206 0.085
Loa Loa (eye worm) hypothetical protein 0.0227 0.0357 0.0814
Schistosoma mansoni aldehyde dehydrogenase 0.0263 0.042 0.1747
Schistosoma mansoni hypothetical protein 0.0092 0.0122 0.0498
Loa Loa (eye worm) endonuclease/Exonuclease/phosphatase 0.0024 0.0003 0.0004
Echinococcus granulosus expressed protein 0.0024 0.0003 0.0001
Schistosoma mansoni aminoadipate-semialdehyde dehydrogenase 0.0067 0.0078 0.0315
Echinococcus multilocularis aldehyde dehydrogenase, mitochondrial 0.0263 0.042 0.0417
Mycobacterium ulcerans hypothetical protein 0.005 0.0048 0.0338
Brugia malayi Thioredoxin reductase 0.0094 0.0124 0.0281
Echinococcus granulosus expressed conserved protein 0.0203 0.0314 0.1304
Plasmodium vivax heat shock protein 86, putative 0.0033 0.0019 0.0128
Leishmania major heat shock protein 83-1 0.0033 0.0019 0.0128
Trichomonas vaginalis hypothetical protein 0.0047 0.0042 0.0139
Brugia malayi orphan nuclear receptor NR2E1 0.0024 0.0003 0.0004
Trichomonas vaginalis chromobox protein, putative 0.0286 0.0459 0.1569
Schistosoma mansoni GTP-binding protein (I) alpha-2 subunit gnai2 0.0024 0.0003 0.0001
Leishmania major heat shock protein 83-1 0.0033 0.0019 0.0128
Loa Loa (eye worm) MBCTL1 0.0159 0.0237 0.054
Echinococcus multilocularis Niemann Pick C1 protein 0.0308 0.0499 0.0496
Wolbachia endosymbiont of Brugia malayi dihydrolipoamide dehydrogenase E3 component 0.0032 0.0017 0.085
Trypanosoma brucei DNA polymerase kappa, putative 0.0173 0.0262 0.2104
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0058 0.0063 0.025
Echinococcus granulosus chromobox protein 1 0.0286 0.0459 0.1909
Echinococcus granulosus smad 0.0042 0.0034 0.013
Brugia malayi Endonuclease/Exonuclease/phosphatase family protein 0.0024 0.0003 0.0004
Brugia malayi Endonuclease/Exonuclease/phosphatase family protein 0.0024 0.0003 0.0004
Echinococcus multilocularis Jumonji, AT rich interactive domain 1B 0.0052 0.0052 0.0049
Loa Loa (eye worm) nuclear hormone receptor 0.0024 0.0003 0.0004
Schistosoma mansoni hypothetical protein 0.0227 0.0357 0.1484
Mycobacterium tuberculosis Probable soluble pyridine nucleotide transhydrogenase SthA (STH) (NAD(P)(+) transhydrogenase [B-specific]) (nicotinamide nucleot 0.0032 0.0017 0.0018
Schistosoma mansoni GTP-binding protein alpha subunit gna 0.0024 0.0003 0.0001
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.0072 0.0087 0.0084
Plasmodium vivax JmjC domain containing protein 0.0048 0.0045 0.0342
Schistosoma mansoni terminal deoxycytidyl transferase 0.0141 0.0206 0.085
Trichomonas vaginalis D-aminoacylase, putative 0.073 0.1233 0.4228
Loa Loa (eye worm) hypothetical protein 0.0037 0.0026 0.0056
Entamoeba histolytica hypothetical protein 0.0049 0.0047 0.0159
Echinococcus granulosus Protein patched homolog 1 0.0093 0.0122 0.05
Onchocerca volvulus 0.0036 0.0024 0.0082
Schistosoma mansoni integrin beta subunit 0.0385 0.0632 0.2633
Loa Loa (eye worm) endonuclease/Exonuclease/phosphatase 0.0024 0.0003 0.0004
Brugia malayi Voltage-gated calcium channel, T-type, alpha subunit. C. elegans cca-1 ortholog 0.0177 0.027 0.0613
Schistosoma mansoni retinoic acid receptor RXR 0.0052 0.0051 0.0199
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0036 0.0024 0.0076
Onchocerca volvulus 0.0036 0.0024 0.0082
Brugia malayi AF-10 protein 0.003 0.0014 0.0028
Plasmodium vivax vivapain-2 0.0036 0.0024 0.017
Plasmodium vivax acyl-CoA synthetase, putative 0.0037 0.0026 0.0184
Plasmodium falciparum conserved Plasmodium membrane protein, unknown function 0.003 0.0014 0.0455
Echinococcus granulosus heat shock protein 90 0.0033 0.0019 0.0066
Echinococcus granulosus zinc finger protein 0.0044 0.0037 0.0142
Schistosoma mansoni hypothetical protein 0.007 0.0082 0.0332
Echinococcus multilocularis polycomb protein SCMH1 0.0139 0.0204 0.0201
Trypanosoma brucei dihydrolipoyl dehydrogenase 0.0032 0.0017 0.0117
Echinococcus granulosus beta LACTamase domain containing family member 0.073 0.1233 0.5152
Trypanosoma brucei polo-like protein kinase 0.0105 0.0145 0.1152
Trypanosoma brucei DNA polymerase kappa, putative 0.0105 0.0144 0.1144
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0052 0.0051 0.0113
Plasmodium vivax ornithine aminotransferase, putative 0.0024 0.0003 0.0001
Schistosoma mansoni lamin 0.019 0.0291 0.1208
Echinococcus multilocularis dna polymerase kappa 0.0173 0.0262 0.0259
Plasmodium vivax aspartyl protease, putative 0.0058 0.0063 0.0485
Onchocerca volvulus 0.0024 0.0003 0.0012
Schistosoma mansoni coup transcription factor 0.0052 0.0051 0.0199
Mycobacterium ulcerans acyl-CoA synthetase 0.005 0.0048 0.0338
Mycobacterium tuberculosis Conserved protein 0.073 0.1233 0.1521
Trypanosoma cruzi hypothetical protein, conserved 0.073 0.1233 1
Loa Loa (eye worm) hypothetical protein 0.0042 0.0034 0.0073
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.026 0.0415 0.1723
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0032 0.0017 0.0117
Echinococcus granulosus integrin alpha 3 0.0245 0.0387 0.1609
Brugia malayi Protein cec-1. 0.0047 0.0042 0.0094
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.0124 0.0178 0.0731
Onchocerca volvulus 0.0058 0.0063 0.0216
Toxoplasma gondii ABC1 family protein 0.073 0.1233 1
Brugia malayi Pre-SET motif family protein 0.0213 0.0333 0.0758
Schistosoma mansoni GTP-binding protein (I) alpha-2 subunit gnai2 0.0024 0.0003 0.0001
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0719 0.1214 0.2773
Brugia malayi Integrin alpha pat-2 precursor 0.0319 0.0517 0.1179
Schistosoma mansoni methyl-cpg binding protein mbd 0.0034 0.0021 0.0074
Schistosoma mansoni hypothetical protein 0.0089 0.0117 0.0475
Trichomonas vaginalis PIKK family atypical protein kinase 0.0032 0.0018 0.0053
Brugia malayi Smad1 0.0042 0.0034 0.0075
Schistosoma mansoni hypothetical protein 0.003 0.0014 0.0044
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0036 0.0024 0.0076
Schistosoma mansoni bromodomain containing protein 0.0132 0.019 0.0784
Trichomonas vaginalis PIKK family atypical protein kinase 0.0026 0.0006 0.0015
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0227 0.0357 0.0814
Mycobacterium ulcerans acetylornithine aminotransferase 0.0024 0.0003 0.0001
Echinococcus granulosus heat shock protein heat shock protein 90 alpha 0.0026 0.0007 0.0017
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0032 0.0017 0.0117
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0227 0.0357 0.0354
Schistosoma mansoni transcription factor LCR-F1 0.019 0.0292 0.1212
Plasmodium vivax SET domain protein, putative 0.0213 0.0333 0.2682
Trichomonas vaginalis D-aminoacylase, putative 0.073 0.1233 0.4228
Echinococcus granulosus survival motor neuron protein 1 0.0772 0.1306 0.5459
Trypanosoma brucei hypothetical protein, conserved 0.0044 0.0037 0.0275
Trypanosoma brucei Heat shock protein 83, putative 0.0033 0.0019 0.0128
Onchocerca volvulus 0.0024 0.0003 0.0012
Plasmodium falciparum DNA repair protein REV1, putative 0.0044 0.0037 0.1478
Echinococcus multilocularis cathepsin d (lysosomal aspartyl protease) 0.0134 0.0195 0.0192
Loa Loa (eye worm) heat shock protein 90 0.0033 0.0019 0.004
Loa Loa (eye worm) hypothetical protein 0.0024 0.0003 0.0004
Schistosoma mansoni nuclear hormone receptor superfamily protein-related 0.0024 0.0003 0.0001
Schistosoma mansoni survival motor neuron protein 0.0157 0.0235 0.0973
Brugia malayi Bromodomain containing protein 0.0101 0.0138 0.0312
Schistosoma mansoni zinc finger protein 0.0031 0.0015 0.0048
Loa Loa (eye worm) hypothetical protein 0.0193 0.0297 0.0676
Toxoplasma gondii GTP-binding nuclear protein ran/tc4 0.0045 0.0039 0.0291
Loa Loa (eye worm) CYP4Cod1 0.0024 0.0003 0.0004
Brugia malayi Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain containing protein 0.0024 0.0002 0.0002
Echinococcus granulosus jumonji domain containing protein 0.0129 0.0185 0.0762
Schistosoma mansoni ecdysone-induced protein 78c (dr-78) 0.0027 0.0008 0.0022
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0036 0.0024 0.0076
Loa Loa (eye worm) hypothetical protein 0.0099 0.0134 0.0303
Echinococcus granulosus snurportin 1 0.0649 0.1092 0.4563
Onchocerca volvulus 0.0036 0.0024 0.0082
Mycobacterium leprae PROBABLE ADENOSYLMETHIONINE-8-AMINO-7-OXONONANOATE AMINOTRANSFERASE BIOA 0.0171 0.0259 0.1938
Loa Loa (eye worm) hypothetical protein 0.073 0.1233 0.2817
Trypanosoma brucei heat shock protein, putative 0.0033 0.0019 0.0128
Plasmodium vivax plasmepsin IV, putative 0.0134 0.0195 0.1562
Brugia malayi follicle stimulating hormone receptor 0.2531 0.4374 1
Echinococcus granulosus Aminotransferase class III 0.0024 0.0003 0.0001
Loa Loa (eye worm) hypothetical protein 0.0052 0.0051 0.0113
Trichomonas vaginalis conserved hypothetical protein 0.0093 0.0122 0.0414
Plasmodium vivax DNA repair protein REV1, putative 0.0044 0.0037 0.0275
Brugia malayi hypothetical protein 0.0024 0.0003 0.0004
Trichomonas vaginalis GTP-binding protein alpha subunit, gna, putative 0.0024 0.0003 0.0005
Echinococcus granulosus histone lysine methyltransferase setb 0.0248 0.0393 0.1632
Trypanosoma brucei DNA polymerase kappa, putative 0.0105 0.0144 0.1144
Mycobacterium ulcerans exodeoxyribonuclease III protein XthA 0.012 0.017 0.1265
Toxoplasma gondii aspartyl protease ASP1 0.0134 0.0195 0.1562
Schistosoma mansoni tar DNA-binding protein 0.045 0.0746 0.3111
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.0052 0.0051 0.0113
Echinococcus multilocularis cathepsin L cysteine protease 0.0036 0.0024 0.0021
Trichomonas vaginalis PIKK family atypical protein kinase 0.0032 0.0018 0.0053
Plasmodium falciparum plasmepsin IX 0.0058 0.0063 0.2608
Plasmodium vivax dihydrolipoyl dehydrogenase, mitochondrial, putative 0.0032 0.0017 0.0117
Mycobacterium tuberculosis Probable fructose-bisphosphate aldolase Fba 0.0782 0.1324 0.1633
Echinococcus multilocularis Smad4 0.0042 0.0034 0.0031
Entamoeba histolytica phosphatidylinositol3-kinaseTor2, putative 0.0044 0.0037 0.0123
Echinococcus multilocularis chromodomain helicase DNA binding protein 4 0.0051 0.0049 0.0046
Trichomonas vaginalis conserved hypothetical protein 0.016 0.024 0.0818
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0047 0.0042 0.0139
Loa Loa (eye worm) hypothetical protein 0.073 0.1233 0.2817
Mycobacterium leprae PROBABLE CHAPERONE PROTEIN HTPG (HEAT SHOCK PROTEIN) (HSP90 FAMILY PROTEIN) (HIGH TEMPERATURE PROTEIN G) 0.0026 0.0007 0.003
Mycobacterium ulcerans beta-lactamase 0.073 0.1233 0.9314
Echinococcus multilocularis traf and tnf receptor associated protein 0.0024 0.0003 0.0000028173
Mycobacterium tuberculosis Probable dehydrogenase 0.0214 0.0333 0.0408
Trypanosoma cruzi mitochondrial DNA polymerase beta, putative 0.0341 0.0555 0.4488
Leishmania major heat shock protein 83-1 0.0033 0.0019 0.0128
Leishmania major target of rapamycin kinase (TOR) kinase 3 0.0035 0.0022 0.0149
Mycobacterium tuberculosis Fatty-acid-AMP ligase FadD30 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) 0.0037 0.0026 0.0028
Leishmania major target of rapamycin (TOR) kinase 2, putative 0.0044 0.0037 0.0276
Brugia malayi Pepsin A precursor 0.0058 0.0063 0.014
Loa Loa (eye worm) hypothetical protein 0.0052 0.0051 0.0113
Schistosoma mansoni polycystin 1-related 0.0042 0.0034 0.0127
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0036 0.0024 0.0076
Brugia malayi Endonuclease/Exonuclease/phosphatase family protein 0.0024 0.0003 0.0004
Echinococcus multilocularis chromodomain helicase DNA binding protein 1 0.0047 0.0042 0.0039
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.012 0.017 0.1358
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.0124 0.0178 0.0175
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0024 0.0003 0.0011
Loa Loa (eye worm) aspartic protease BmAsp-1 0.0058 0.0063 0.014
Schistosoma mansoni RAR-like nuclear receptor 0.0052 0.0051 0.0199
Onchocerca volvulus Cathepsin L homolog 0.0036 0.0024 0.0082
Leishmania major heat shock protein 83-1 0.0033 0.0019 0.0128
Trypanosoma brucei DNA damage repair protein, putative 0.0044 0.0037 0.0275
Trichomonas vaginalis carbon catabolite repressor protein, putative 0.0024 0.0003 0.0004
Schistosoma mansoni ran 0.0045 0.0039 0.015
Loa Loa (eye worm) mbt repeat family protein 0.0139 0.0204 0.0463
Entamoeba histolytica heat shock protein 90, putative 0.0033 0.0019 0.0057
Echinococcus granulosus nuclear receptor nhr 48 0.0024 0.0003 0.0001
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0568 0.0951 0.2171
Entamoeba histolytica cysteine proteinase, putative 0.0036 0.0024 0.0076
Trypanosoma brucei target of rapamycin kinase 3, putative 0.0035 0.0022 0.0149
Echinococcus multilocularis arachidonate 5 lipoxygenase 0.0178 0.0272 0.0269
Mycobacterium tuberculosis Probable membrane NADH dehydrogenase NdhA 0.0214 0.0333 0.0408
Schistosoma mansoni aldehyde dehydrogenase 0.0263 0.042 0.1747
Toxoplasma gondii fructose-bisphosphate aldolase, putative 0.011 0.0152 0.1212
Trichomonas vaginalis glutathione reductase, putative 0.0032 0.0017 0.0053
Echinococcus granulosus ornithine aminotransferase 0.0024 0.0003 0.0001
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.16 0.2751 0.944
Echinococcus granulosus Chromo domain 0.0047 0.0042 0.0165
Brugia malayi acetyltransferase, GNAT family protein 0.018 0.0274 0.0624
Trypanosoma brucei trypanothione reductase 0.0094 0.0124 0.0984
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0206 0.0319 0.1324
Trypanosoma cruzi phosphomannose isomerase, putative 0.0099 0.0134 0.1065
Echinococcus granulosus muscleblind protein 0.0337 0.0549 0.2287
Schistosoma mansoni hypothetical protein 0.0649 0.1092 0.4563
Echinococcus granulosus chromodomain helicase DNA binding protein 4 0.0051 0.0049 0.0193
Echinococcus multilocularis SAM and MBT domain containing protein 0.0139 0.0204 0.0201
Echinococcus multilocularis inositol polyphosphate 5 phosphatase OCRL 1 0.0024 0.0003 0.0000028173
Schistosoma mansoni myelin transcription factor 1 myt1 0.0159 0.0237 0.0982
Brugia malayi GTP-binding nuclear protein RAN/TC4 0.0045 0.0039 0.0086
Loa Loa (eye worm) RNA binding protein 0.045 0.0746 0.1702
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0052 0.0051 0.0199
Loa Loa (eye worm) guanine nucleotide-binding protein alpha-12 subunit 0.0024 0.0003 0.0004
Mycobacterium ulcerans 4-aminobutyrate aminotransferase 0.0024 0.0003 0.0001
Echinococcus granulosus short transient receptor potential channel 6 0.0057 0.006 0.0238
Mycobacterium tuberculosis Probable mannose-6-phosphate isomerase ManA (phosphomannose isomerase) (phosphomannoisomerase) (PMI) (phosphohexoisomerase) (pho 0.0054 0.0055 0.0064
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0036 0.0024 0.0076
Plasmodium falciparum mannose-6-phosphate isomerase, putative 0.0099 0.0134 0.5722
Schistosoma mansoni GTP-binding protein (I) alpha-2 subunit gnai2 0.0024 0.0003 0.0001
Echinococcus multilocularis RUN 0.0042 0.0034 0.003
Echinococcus granulosus tyrosine protein phosphatase non receptor type 0.0294 0.0473 0.1967
Brugia malayi Bromodomain containing protein 0.0155 0.0231 0.0526
Loa Loa (eye worm) hypothetical protein 0.073 0.1233 0.2817
Loa Loa (eye worm) heterochromatin protein 1 0.0286 0.0459 0.1046
Trypanosoma cruzi PAB1-binding protein , putative 0.0155 0.0232 0.1861
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0044 0.0037 0.0081
Schistosoma mansoni ubiquitously transcribed sex (X/Y) chromosome tetratricopeptide repeat protein-related 0.0048 0.0045 0.0176
Trichomonas vaginalis ocrl type II inositol 5-phosphatase, putative 0.0024 0.0003 0.0004
Echinococcus granulosus fetal alzheimer antigen falz 0.0045 0.004 0.0154
Onchocerca volvulus 0.0139 0.0204 0.07
Trichomonas vaginalis chromobox protein, putative 0.0047 0.0042 0.0139
Trypanosoma brucei DNA polymerase kappa, putative 0.0173 0.0262 0.2104
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.0052 0.0051 0.0048
Brugia malayi Endonuclease/Exonuclease/phosphatase family protein 0.0024 0.0003 0.0004
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.1488 0.2555 0.584
Schistosoma mansoni chromobox protein 0.0047 0.0042 0.0165
Brugia malayi Cathepsin L-like precursor 0.0036 0.0024 0.0052
Brugia malayi hypothetical protein 0.0047 0.0042 0.0094
Trypanosoma brucei heat shock protein, putative 0.0033 0.0019 0.0128
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0227 0.0357 0.1484
Loa Loa (eye worm) hypothetical protein 0.0024 0.0003 0.0004
Schistosoma mansoni jun-related protein 0.0082 0.0105 0.0425
Echinococcus granulosus cathepsin l1 0.0036 0.0024 0.0087
Loa Loa (eye worm) hypothetical protein 0.0047 0.0042 0.0094
Echinococcus multilocularis integrin alpha ps 0.0143 0.021 0.0207
Loa Loa (eye worm) hypothetical protein 0.0134 0.0195 0.0443
Brugia malayi Guanine nucleotide-binding protein alpha-3 subunit, putative 0.0024 0.0003 0.0004
Loa Loa (eye worm) bromodomain containing protein 0.004 0.003 0.0066
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.0052 0.0051 0.0113
Brugia malayi mbt repeat family protein 0.0139 0.0204 0.0463
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0032 0.0017 0.0117
Brugia malayi C2-HC type zinc finger protein C.e-MyT1 0.0159 0.0237 0.054
Schistosoma mansoni hypothetical protein 0.0082 0.0105 0.0425
Loa Loa (eye worm) endonuclease/Exonuclease/phosphatase 0.0024 0.0003 0.0004
Echinococcus granulosus sterol regulatory element binding protein 0.0093 0.0122 0.05
Leishmania major hypothetical protein, conserved 0.0048 0.0045 0.0342
Leishmania major 3-oxoacyl-(acyl-carrier protein) reductase, putative 0.0061 0.0067 0.0516
Echinococcus granulosus aldehyde dehydrogenase mitochondrial 0.0263 0.042 0.1747
Echinococcus granulosus Smad4 0.0042 0.0034 0.013
Schistosoma mansoni trimeric G-protein alpha o subunit 0.0024 0.0003 0.0001
Loa Loa (eye worm) endonuclease/Exonuclease/phosphatase 0.0024 0.0003 0.0004
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0036 0.0024 0.0076
Loa Loa (eye worm) heterotrimeric G protein alpha subunit 0.0024 0.0003 0.0004
Toxoplasma gondii histone lysine demethylase JMJC1/KDM5D/JARID1D 0.0048 0.0045 0.0342
Echinococcus granulosus heat shock protein 90 0.0026 0.0007 0.0017
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0047 0.0042 0.0139
Schistosoma mansoni chromobox protein 0.0286 0.0459 0.1909
Brugia malayi serine/threonine-protein kinase plk-2 0.0105 0.0145 0.0328
Loa Loa (eye worm) hypothetical protein 0.0024 0.0003 0.0004
Mycobacterium ulcerans acyl-CoA synthetase 0.005 0.0048 0.0338
Trichomonas vaginalis PIKK family atypical protein kinase 0.0026 0.0006 0.0014
Echinococcus multilocularis cytoplasmic intermediate filament protein 0.0091 0.012 0.0117
Echinococcus granulosus SAM and MBT domain containing protein 0.0139 0.0204 0.0841
Schistosoma mansoni tar DNA-binding protein 0.045 0.0746 0.3111
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0036 0.0024 0.0076
Echinococcus granulosus integrin beta 2 0.0484 0.0805 0.3358
Leishmania major heat shock protein 83-1 0.0033 0.0019 0.0128
Mycobacterium tuberculosis Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) 0.012 0.017 0.0207
Brugia malayi latrophilin 2 splice variant baaae 0.0491 0.0817 0.1866
Brugia malayi Heterochromatin protein 1 0.0286 0.0459 0.1046
Onchocerca volvulus Cathepsin L homolog 0.0036 0.0024 0.0082
Trichomonas vaginalis heat shock protein, putative 0.0033 0.0019 0.0058
Trypanosoma cruzi cysteine peptidase, putative 0.0036 0.0024 0.017
Loa Loa (eye worm) hypothetical protein 0.0024 0.0003 0.0004
Brugia malayi Steroid receptor seven-up type 2 0.0052 0.0051 0.0113
Trypanosoma cruzi DNA polymerase kappa, putative 0.0173 0.0262 0.2104
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0036 0.0024 0.0076
Toxoplasma gondii ornithine aminotransferase, mitochondrial precursor, putative 0.0024 0.0003 0.0001
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.0052 0.0051 0.0048
Brugia malayi nuclear hormone receptor 0.0024 0.0003 0.0004
Brugia malayi Nuclear hormone receptor family member nhr-49 0.0052 0.0051 0.0113
Onchocerca volvulus 0.0024 0.0003 0.0011
Trypanosoma cruzi cysteine peptidase, clan CA, family C1, cathepsin L-like, putative 0.0126 0.018 0.1442
Schistosoma mansoni chromobox protein 0.0047 0.0042 0.0165
Loa Loa (eye worm) kelch domain-containing protein family protein 0.0099 0.0134 0.0303
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD7 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.005 0.0048 0.0338
Echinococcus granulosus fructose 16 bisphosphate aldolase 0.011 0.0152 0.0624
Schistosoma mansoni GTP-binding protein alpha subunit 0.0024 0.0003 0.0001
Brugia malayi Doublecortin family protein 0.0042 0.0034 0.0073
Schistosoma mansoni protein tyrosine phosphatase non-receptor type nt1 0.0294 0.0473 0.1967
Loa Loa (eye worm) hypothetical protein 0.0024 0.0003 0.0004
Giardia lamblia GTOR 0.0044 0.0037 0.0123
Loa Loa (eye worm) hypothetical protein 0.0037 0.0026 0.0056
Entamoeba histolytica hypothetical protein 0.019 0.0292 0.1053
Brugia malayi beta-lactamase 0.073 0.1233 0.2817
Loa Loa (eye worm) jmjC domain-containing protein 0.0048 0.0045 0.01
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0568 0.0951 0.3969
Loa Loa (eye worm) guanine nucleotide-binding protein alpha-6 subunit 0.0024 0.0003 0.0004
Loa Loa (eye worm) hypothetical protein 0.005 0.0048 0.0106
Mycobacterium ulcerans 4-aminobutyrate aminotransferase 0.0024 0.0003 0.0001
Trichomonas vaginalis PIKK family atypical protein kinase 0.0044 0.0037 0.012
Loa Loa (eye worm) hypothetical protein 0.0036 0.0024 0.0052
Brugia malayi AMP-binding enzyme family protein 0.005 0.0048 0.0106
Loa Loa (eye worm) integrin alpha pat-2 0.0492 0.0818 0.1868
Trypanosoma brucei heat shock protein 90, putative 0.0033 0.0019 0.0128
Plasmodium vivax hypothetical protein, conserved 0.0047 0.0042 0.0319
Schistosoma mansoni transient receptor potential channel 0.0057 0.006 0.0238
Plasmodium falciparum plasmepsin VIII, putative 0.0058 0.0063 0.2608
Mycobacterium ulcerans long-chain-fatty-acid-CoA ligase 0.005 0.0048 0.0338
Plasmodium falciparum thioredoxin reductase 0.0032 0.0017 0.0626
Trichomonas vaginalis conserved hypothetical protein 0.0047 0.0042 0.0139
Loa Loa (eye worm) hypothetical protein 0.0024 0.0003 0.0004
Trypanosoma cruzi hypothetical protein, conserved 0.073 0.1233 1
Trypanosoma cruzi mitochondrial DNA polymerase beta, putative 0.0341 0.0555 0.4488
Echinococcus multilocularis fructose 1,6 bisphosphate aldolase 0.011 0.0152 0.0149
Mycobacterium ulcerans esterase/lipase LipP 0.073 0.1233 0.9314
Echinococcus multilocularis cathepsin l cysteine peptidase 0.0036 0.0024 0.0021
Mycobacterium ulcerans mannose-6-phosphate isomerase ManA 0.0099 0.0134 0.0992
Toxoplasma gondii PHD-finger domain-containing protein 0.0092 0.0122 0.0967
Brugia malayi ImpB/MucB/SamB family protein 0.0141 0.0206 0.0468
Plasmodium falciparum ataxin-2 like protein, putative 0.0155 0.0232 1
Echinococcus granulosus nuclear receptor subfamily 4 group A 0.0024 0.0003 0.0001
Leishmania major GTP-binding protein, putative 0.0045 0.0039 0.0291
Entamoeba histolytica Ran family GTPase 0.0045 0.0039 0.013
Loa Loa (eye worm) glutaminase 2 0.033 0.0536 0.1223
Trichomonas vaginalis sphingomyelinase C 2 precursor, putative 0.0024 0.0003 0.0004
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0138 0.0201 0.1611
Leishmania major cathepsin L-like protease 0.0036 0.0024 0.017
Brugia malayi Cathepsin L-like precursor 0.0024 0.0003 0.0004
Echinococcus multilocularis jun protein 0.0101 0.0138 0.0135
Trichomonas vaginalis PIKK family atypical protein kinase 0.0029 0.0012 0.0034
Schistosoma mansoni hypothetical protein 0.0047 0.0042 0.0165
Brugia malayi Nuclear hormone receptor-like 1 0.0027 0.0008 0.0016
Onchocerca volvulus 0.073 0.1233 0.4232
Schistosoma mansoni smad 0.0042 0.0034 0.013
Echinococcus granulosus gtp binding protein I alpha 1subunit 0.0024 0.0003 0.0001
Treponema pallidum heat shock protein 90 0.0026 0.0007 0.0014
Plasmodium vivax hypothetical protein, conserved 0.003 0.0014 0.0085
Echinococcus granulosus RUN 0.0042 0.0034 0.0127
Loa Loa (eye worm) hypothetical protein 0.0048 0.0045 0.01
Echinococcus granulosus Nuclear hormone receptor HR96 0.0024 0.0003 0.0001
Echinococcus granulosus lysine specific demethylase 6a 0.0048 0.0045 0.0176
Plasmodium falciparum AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.012 0.017 0.7298
Trypanosoma cruzi DNA polymerase kappa, putative 0.0173 0.0262 0.2104
Brugia malayi hypothetical protein 0.01 0.0136 0.0307
Trichomonas vaginalis skeletal muscle/kidney enriched inositol 5-phosphatase, putative 0.0024 0.0003 0.0004
Echinococcus multilocularis transient receptor potential ion channel A 0.0076 0.0093 0.009
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.073 0.1233 0.1521
Echinococcus granulosus 3 hydroxyacyl coenzyme A dehydrogenase type 2 0.0061 0.0067 0.0266
Echinococcus granulosus TRP transient receptor potential channel 0.0034 0.002 0.0071
Leishmania major apurinic/apyrimidinic endonuclease-redox protein 0.012 0.017 0.1358
Trypanosoma cruzi trypanothione reductase, putative 0.0032 0.0017 0.0117
Echinococcus multilocularis thyroid hormone receptor alpha 0.0174 0.0264 0.0261
Trichomonas vaginalis GTP-binding protein alpha subunit, gna, putative 0.0024 0.0003 0.0005
Mycobacterium ulcerans lipase LipD 0.073 0.1233 0.9314
Leishmania major lipophosphoglycan biosynthetic protein, putative,heat shock protein 90, putative,glucose regulated protein 94, putative 0.0026 0.0007 0.0032
Trichomonas vaginalis PIKK family atypical protein kinase 0.0035 0.0021 0.0067
Loa Loa (eye worm) hypothetical protein 0.0037 0.0026 0.0056
Brugia malayi nuclear hormone receptor family member odr-7 0.0024 0.0003 0.0004
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0058 0.0063 0.025
Schistosoma mansoni dihydrolipoamide dehydrogenase 0.0032 0.0017 0.006
Echinococcus multilocularis lipoxygenase domain containing protein 0.0042 0.0034 0.003
Plasmodium falciparum plasmepsin II 0.0134 0.0195 0.8396
Echinococcus granulosus cathepsin l1 0.0024 0.0003 0.0000094491
Brugia malayi Cathepsin L-like cysteine proteinase 0.0024 0.0003 0.0004
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.0052 0.0051 0.0199
Echinococcus multilocularis lysine specific demethylase 5A 0.0181 0.0277 0.0274
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.16 0.2751 0.944
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0032 0.0017 0.0117
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.0052 0.0051 0.0199
Mycobacterium ulcerans aldehyde dehydrogenase 0.0263 0.042 0.3158
Echinococcus multilocularis mothers against decapentaplegic 5 0.0042 0.0034 0.0031
Echinococcus granulosus GTP binding nuclear protein Ran 0.0045 0.0039 0.015
Loa Loa (eye worm) Smad1 0.0042 0.0034 0.0075
Echinococcus granulosus tar DNA binding protein 0.045 0.0746 0.3111
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0032 0.0017 0.0117
Echinococcus granulosus FTZ F1 alpha 0.0052 0.0051 0.0199
Echinococcus granulosus lamin dm0 0.019 0.0291 0.1208
Schistosoma mansoni jumonji/arid domain-containing protein 0.0185 0.0284 0.1176
Trypanosoma brucei mitochondrial DNA polymerase beta 0.0341 0.0555 0.4488
Brugia malayi hypothetical protein 0.008 0.01 0.0225
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0047 0.0042 0.0139
Schistosoma mansoni 3-hydroxyacyl-CoA dehydrogenase 0.0061 0.0067 0.0266
Loa Loa (eye worm) hypothetical protein 0.0047 0.0042 0.0094
Loa Loa (eye worm) fibroinase 0.0036 0.0024 0.0052
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0024 0.0003 0.0011
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative 0.012 0.017 0.1358
Brugia malayi AMP-binding enzyme family protein 0.005 0.0048 0.0106
Trypanosoma brucei PHD-zinc-finger like domain containing protein, putative 0.003 0.0014 0.0085
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0049 0.0047 0.0154
Loa Loa (eye worm) hypothetical protein 0.0047 0.0042 0.0094
Echinococcus granulosus chromodomain helicase DNA binding protein 1 0.0047 0.0042 0.0165
Trypanosoma brucei heat shock protein, putative 0.0033 0.0019 0.0128
Plasmodium falciparum JmjC domain-containing protein, putative 0.0048 0.0045 0.184
Echinococcus multilocularis lamin 0.019 0.0291 0.0288
Toxoplasma gondii heat shock protein HSP90 0.0033 0.0019 0.0128
Schistosoma mansoni hypothetical protein 0.0042 0.0033 0.0126
Echinococcus granulosus lysine specific demethylase 5A 0.0185 0.0284 0.1176
Trypanosoma cruzi fructose-bisphosphate aldolase, glycosomal, putative 0.011 0.0152 0.1212
Schistosoma mansoni cathepsin D (A01 family) 0.0328 0.0533 0.222
Echinococcus multilocularis cathepsin L cysteine protease 0.0036 0.0024 0.0021
Brugia malayi alpha keto acid dehydrogenase complex, E3 component, lipoamide dehydrogenase 0.0024 0.0002 0.0002
Brugia malayi Endonuclease/Exonuclease/phosphatase family protein 0.0024 0.0003 0.0004
Plasmodium falciparum heterochromatin protein 1 0.0047 0.0042 0.1715
Mycobacterium tuberculosis Probable phytoene synthase PhyA 0.0094 0.0125 0.0151
Trichomonas vaginalis CAMK family protein kinase 0.0105 0.0145 0.0491
Brugia malayi bZIP transcription factor family protein 0.0101 0.0138 0.0312
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0036 0.0024 0.0076
Echinococcus granulosus integrin alpha ps 0.0143 0.021 0.0868
Plasmodium falciparum glutathione reductase 0.0032 0.0017 0.0626
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0037 0.0026 0.0172
Brugia malayi nuclear receptor subfamily 1, group D, member 1, putative 0.0024 0.0003 0.0004
Trypanosoma cruzi cysteine peptidase, putative 0.0138 0.0201 0.1611
Loa Loa (eye worm) beta-lactamase 0.073 0.1233 0.2817
Loa Loa (eye worm) hypothetical protein 0.0027 0.0008 0.0016
Echinococcus multilocularis GPCR, family 2 0.0227 0.0357 0.0354
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0036 0.0024 0.0076
Echinococcus multilocularis Ataxin 2, N terminal,domain containing protein 0.007 0.0082 0.0079
Brugia malayi MH1 domain containing protein 0.0042 0.0034 0.0075
Echinococcus granulosus short transient receptor potential channel 6 0.0057 0.006 0.0238
Echinococcus granulosus lipoxygenase domain containing protein 0.0042 0.0034 0.0127
Echinococcus granulosus guanine nucleotide binding protein G protein 0.0024 0.0003 0.0001
Brugia malayi nuclear hormone receptor 0.0052 0.0051 0.0113
Echinococcus granulosus chromobox protein 1 0.0286 0.0459 0.1909
Loa Loa (eye worm) hypothetical protein 0.0024 0.0003 0.0004
Schistosoma mansoni methyl-cpg binding protein mbd 0.0034 0.0021 0.0074
Brugia malayi Calcitonin receptor-like protein seb-1 0.0719 0.1214 0.2773
Schistosoma mansoni phd/f-box containing protein 0.0048 0.0045 0.0176
Trypanosoma brucei heat shock protein, putative 0.0033 0.0019 0.0128
Brugia malayi Nuclear hormone receptor family member nhr-40 0.0052 0.0051 0.0113
Loa Loa (eye worm) hypothetical protein 0.0433 0.0716 0.1634
Schistosoma mansoni nuclear receptor nhr-48 0.0024 0.0003 0.0001
Echinococcus multilocularis Squalene phytoene synthase 0.0094 0.0125 0.0122
Loa Loa (eye worm) hypothetical protein 0.0027 0.0008 0.0016
Mycobacterium ulcerans hypothetical protein 0.0171 0.0259 0.1938
Echinococcus multilocularis Chromo domain 0.0047 0.0042 0.0039
Schistosoma mansoni gcn5proteinral control of amino-acid synthesis 5-like 2 gcnl2 0.018 0.0274 0.1136
Schistosoma mansoni nuclear hormone receptor 0.0024 0.0003 0.0001
Brugia malayi Endonuclease/Exonuclease/phosphatase family protein 0.0024 0.0003 0.0004
Echinococcus multilocularis jumonji domain containing 1A 0.0048 0.0045 0.0042
Schistosoma mansoni nuclear hormone receptor 0.0024 0.0003 0.0001
Brugia malayi Niemann-Pick C1 protein precursor 0.0216 0.0337 0.0768
Schistosoma mansoni ataxia telangiectasia mutated (atm)-related 0.0044 0.0037 0.0142
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0047 0.0042 0.0139
Loa Loa (eye worm) hypothetical protein 0.0337 0.0549 0.1252
Entamoeba histolytica cysteine proteinase, putative 0.0036 0.0024 0.0076
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0058 0.0063 0.025
Trypanosoma cruzi pantothenate kinase subunit, putative 0.0026 0.0007 0.0029
Loa Loa (eye worm) hypothetical protein 0.0024 0.0003 0.0004
Toxoplasma gondii target of rapamycin (TOR), putative 0.0032 0.0018 0.0117
Giardia lamblia PHD finger protein 15 0.0092 0.0122 0.0433
Trypanosoma brucei DNA polymerase IV, putative 0.0165 0.0248 0.1991
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.0052 0.0051 0.0199
Trypanosoma brucei DNA polymerase kappa, putative 0.0173 0.0262 0.2104
Brugia malayi hypothetical protein 0.019 0.0292 0.0665
Trypanosoma brucei JmjC domain, hydroxylase, putative 0.0048 0.0045 0.0342
Schistosoma mansoni steroid hormone receptor ad4bp 0.0052 0.0051 0.0199
Trypanosoma brucei DNA polymerase kappa, putative 0.0173 0.0262 0.2104
Brugia malayi tailless protein 0.0024 0.0003 0.0004
Echinococcus multilocularis L aminoadipate semialdehyde 0.0067 0.0078 0.0075
Trichomonas vaginalis CAMK family protein kinase 0.0105 0.0145 0.0491
Trichomonas vaginalis conserved hypothetical protein 0.0047 0.0042 0.0139

Activities

Activity type Activity value Assay description Source Reference
GI50 (functional) -4.829 PUBCHEM_BIOASSAY: NCI human tumor cell line growth inhibition assay. Data for the HL-60(TB) Leukemia cell line. (Class of assay: confirmatory) ChEMBL. No reference
GI50 (functional) -4.692 PUBCHEM_BIOASSAY: NCI human tumor cell line growth inhibition assay. Data for the UO-31 Renal cell line. (Class of assay: confirmatory) ChEMBL. No reference
GI50 (functional) -4.664 PUBCHEM_BIOASSAY: NCI human tumor cell line growth inhibition assay. Data for the SN12C Renal cell line. (Class of assay: confirmatory) ChEMBL. No reference
GI50 (functional) -4.551 PUBCHEM_BIOASSAY: NCI human tumor cell line growth inhibition assay. Data for the SF-539 Central Nervous System cell line. (Class of assay: confirmatory) ChEMBL. No reference
GI50 (functional) -4.538 PUBCHEM_BIOASSAY: NCI human tumor cell line growth inhibition assay. Data for the NCI-H23 Non-Small Cell Lung cell line. (Class of assay: confirmatory) ChEMBL. No reference
GI50 (functional) -4.448 PUBCHEM_BIOASSAY: NCI human tumor cell line growth inhibition assay. Data for the DU-145 Prostate cell line. (Class of assay: confirmatory) ChEMBL. No reference
GI50 (functional) -4.408 PUBCHEM_BIOASSAY: NCI human tumor cell line growth inhibition assay. Data for the SK-MEL-5 Melanoma cell line. (Class of assay: confirmatory) ChEMBL. No reference
GI50 (functional) -4.391 PUBCHEM_BIOASSAY: NCI human tumor cell line growth inhibition assay. Data for the ACHN Renal cell line. (Class of assay: confirmatory) ChEMBL. No reference
GI50 (functional) -4.328 PUBCHEM_BIOASSAY: NCI human tumor cell line growth inhibition assay. Data for the MDA-N Breast cell line. (Class of assay: confirmatory) ChEMBL. No reference
IC50 (binding) = 9000 nM In vitro inhibitory activity against rat squalene synthase ChEMBL. No reference
IC50 (binding) = 9000 nM In vitro inhibitory activity against rat squalene synthase ChEMBL. No reference
Inhibition (functional) = 0 % In vivo inhibitory activity against mouse hepatic cholesterol synthesis administered orally at 48 mpk ChEMBL. No reference
Inhibition (functional) = 0 % In vivo inhibitory activity against mouse hepatic cholesterol synthesis administered orally at 48 mpk ChEMBL. No reference
Potency (functional) 1.122 uM PUBCHEM_BIOASSAY: qHTS Assay for Inhibitors of GCN5L2. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID504398] ChEMBL. No reference
Potency (functional) 10 uM PUBCHEM_BIOASSAY: Inhibitors of the vitamin D receptor (VDR): qHTS. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID504855] ChEMBL. No reference
Potency (functional) 12.5893 uM PubChem BioAssay. qHTS for Inhibitors of Glutaminase (GLS). (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) 15.8489 uM PUBCHEM_BIOASSAY: qHTS for Inhibitors of Polymerase Kappa. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID588638] ChEMBL. No reference
Potency (functional) 16.9301 uM PubChem BioAssay: Tox21. qHTS assay to identify small molecule agonists of the AP-1 signaling pathway. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) 18.8322 uM PubChem BioAssay: Tox21. qHTS assay for small molecule agonists of the antioxidant response element (ARE) signaling pathway. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) 22.3872 uM PUBCHEM_BIOASSAY: Inhibitors of USP1/UAF1: Pilot qHTS. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID504878] ChEMBL. No reference
Potency (functional) 26.6011 uM PubChem BioAssay: Tox21. qHTS assay for small molecule activators of the heat shock response signaling pathway. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) 26.8325 uM PubChem BioAssay: Tox21. qHTS assay to identify small molecule agonists of the androgen receptor (AR) signaling pathway. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) 26.8325 uM PubChem BioAssay: Tox21. qHTS assay to identify small molecule agonists of the NFkB signaling pathway. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) 29.8554 uM PubChem BioAssay. A quantitative high throughput screen for small molecules that induce DNA re-replication in MCF 10a normal breast cells. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) 32.1968 uM PUBCHEM_BIOASSAY: Biochemical firefly luciferase enzyme assay for NPC. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) = 39.8107 um PUBCHEM_BIOASSAY: qHTS Assay for Inhibitors of Bloom's syndrome helicase (BLM). (Class of assay: confirmatory) [Related pubchem assays: 593 (Fluorescein region spectral profiling screen), 2386 (Probe Development Summary for Inhibitors of Bloom's syndrome helicase (BLM)), 594 (Rhodamine region spectral profiling screen), 2364 (qHTS Validation Assay for Inhibitors of Bloom's syndrome helicase (BLM))] ChEMBL. No reference

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

Affected Entity Phenotypic quality Occurs in Occurs at Evidence Observed in Targets
catalytic activity (GO:0003824) decreased (PATO:0000468) in vitro (MI:0492) inferred from specific protein inhibition (ECO:0000020) Leishmania mexicana 21366  
Annotator: aaronjr@u.washington.edu Comment: chemical inhibition with ALD inhibitors leads to reduced enzyme activity in vitro; References: 10551371

In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

Bibliographic References

5 literature references were collected for this gene.

If you have references for this compound, please enter them in a user comment (below) or Contact us.