Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Mycobacterium leprae | Probable adenosine deaminase Add (ADENOSINE AMINOHYDROLASE) | 0.0104 | 1 | 0.5 |
Treponema pallidum | adenosine deaminase | 0.0104 | 1 | 0.5 |
Plasmodium vivax | adenosine deaminase, putative | 0.0104 | 1 | 0.5 |
Trichomonas vaginalis | adenosine deaminase, putative | 0.0104 | 1 | 0.5 |
Mycobacterium tuberculosis | Probable adenosine deaminase Add (adenosine aminohydrolase) | 0.0104 | 1 | 0.5 |
Echinococcus granulosus | adenosine deaminase | 0.0104 | 1 | 0.5 |
Entamoeba histolytica | adenosine deaminase, putative | 0.0104 | 1 | 0.5 |
Toxoplasma gondii | Adenosine/AMP deaminase domain-containing protein | 0.0104 | 1 | 0.5 |
Echinococcus multilocularis | adenosine deaminase | 0.0104 | 1 | 0.5 |
Toxoplasma gondii | Adenosine/AMP deaminase domain-containing protein | 0.0104 | 1 | 0.5 |
Schistosoma mansoni | adenosine deaminase-related | 0.0104 | 1 | 0.5 |
Schistosoma mansoni | adenosine deaminase | 0.0104 | 1 | 0.5 |
Plasmodium falciparum | adenosine deaminase | 0.0104 | 1 | 0.5 |
Entamoeba histolytica | adenosine deaminase, putative | 0.0104 | 1 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0104 | 1 | 1 |
Trichomonas vaginalis | adenosine deaminase, putative | 0.0104 | 1 | 0.5 |
Onchocerca volvulus | Adenosine deaminase homolog | 0.0104 | 1 | 0.5 |
Leishmania major | adenine aminohydrolase | 0.0104 | 1 | 0.5 |
Mycobacterium ulcerans | adenosine deaminase | 0.0104 | 1 | 0.5 |
Activity type | Activity value | Assay description | Source | Reference |
---|---|---|---|---|
Potency (functional) | = 35.4813 um | PUBCHEM_BIOASSAY: qHTS Assay for Inhibitors of Human Jumonji Domain Containing 2E (JMJD2E). (Class of assay: confirmatory) | ChEMBL. | No reference |
Potency (functional) | = 39.8107 um | PUBCHEM_BIOASSAY: qHTS Assay for Activators of Human Muscle isoform 2 Pyruvate Kinase. (Class of assay: confirmatory) | ChEMBL. | No reference |
Potency (functional) | = 39.8107 um | PUBCHEM_BIOASSAY: qHTS Assay for Inhibitors of Human Muscle isoform 2 Pyruvate Kinase. (Class of assay: confirmatory) [Related pubchem assays: 1379 ] | ChEMBL. | No reference |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.