Detailed information for compound 1324330

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 329.307 | Formula: C16H15N3O5
  • H donors: 2 H acceptors: 4 LogP: 1.23 Rotable bonds: 7
    Rule of 5 violations (Lipinski): 1
  • SMILES: COc1c(OC)ccc(c1C(=O)O)C=NNC(=O)c1ccncc1
  • InChi: 1S/C16H15N3O5/c1-23-12-4-3-11(13(16(21)22)14(12)24-2)9-18-19-15(20)10-5-7-17-8-6-10/h3-9H,1-2H3,(H,19,20)(H,21,22)
  • InChiKey: HSYFNANHKYNZNI-UHFFFAOYSA-N  

Network

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity

Obtained from network model

Ranking Plot


Putative Targets List


Species Potential target Raw Global Species
Mycobacterium tuberculosis Possible cytochrome P450 135A1 Cyp135A1 0.0011 0.0007 0.0001
Mycobacterium tuberculosis Phenolpthiocerol synthesis type-I polyketide synthase PpsD 0.0024 0.0108 0.0143
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0031 0.0159 0.0593
Mycobacterium tuberculosis Phenolpthiocerol synthesis type-I polyketide synthase PpsC 0.0024 0.0108 0.0143
Brugia malayi Latrophilin receptor protein 2 0.0016 0.0043 0.028
Trichomonas vaginalis esterase, putative 0.0037 0.0205 0.0871
Brugia malayi nuclear receptor NHR-88 0.0014 0.0033 0.0217
Mycobacterium tuberculosis Possible cytochrome P450 135B1 Cyp135B1 0.0011 0.0007 0.0001
Loa Loa (eye worm) nuclear hormone receptor-like 1 0.0016 0.0047 0.0297
Schistosoma mansoni nuclear receptor 0.0014 0.0033 0.0103
Loa Loa (eye worm) acyl carrier protein 0.0012 0.0017 0.0106
Trypanosoma brucei mitochondrial DNA polymerase beta-PAK 0.0139 0.0985 0.453
Mycobacterium leprae PHENOLPTHIOCEROL SYNTHESIS TYPE-I POLYKETIDE SYNTHASE PPSC 0.0026 0.0121 0.0159
Brugia malayi hypothetical protein 0.0016 0.0047 0.0303
Brugia malayi nuclear receptor NHR-88 0.003 0.0156 0.1016
Trypanosoma cruzi tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0068 0.0441 0.201
Giardia lamblia Myb 1-like protein 0.0019 0.0072 0.0227
Loa Loa (eye worm) hypothetical protein 0.0016 0.0047 0.0297
Trypanosoma brucei cytochrome P450, putative 0.002 0.0076 0.0318
Mycobacterium tuberculosis Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras 0.0097 0.0665 0.0921
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.003 0.0156 0.0603
Schistosoma mansoni tyrosyl-DNA phosphodiesterase 0.0068 0.0441 0.1688
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0037 0.0205 0.0771
Mycobacterium leprae PHENOLPTHIOCEROL SYNTHESIS TYPE-I POLYKETIDE SYNTHASE PPSB 0.0019 0.0068 0.0086
Mycobacterium tuberculosis Probable cytochrome P450 132 Cyp132 0.0011 0.0007 0.0001
Echinococcus granulosus cpg binding protein 0.0031 0.0158 0.0611
Brugia malayi nuclear hormone receptor family member nhr-6 0.0014 0.0033 0.0217
Mycobacterium ulcerans thioesterase 0.0022 0.0093 0.0086
Loa Loa (eye worm) AMP-binding enzyme family protein 0.0025 0.0114 0.0734
Mycobacterium tuberculosis Phenolpthiocerol synthesis type-I polyketide synthase PpsA 0.0024 0.0108 0.0143
Echinococcus multilocularis nuclear receptor subfamily 1 group D 0.0016 0.0047 0.0177
Loa Loa (eye worm) hypothetical protein 0.0014 0.0033 0.0212
Loa Loa (eye worm) hypothetical protein 0.0012 0.0019 0.0117
Plasmodium vivax hypothetical protein, conserved 0.0037 0.0205 0.6339
Mycobacterium tuberculosis Probable polyketide synthase Pks8 0.0019 0.0071 0.0091
Onchocerca volvulus 0.0031 0.0159 0.073
Trichomonas vaginalis MYB, putative 0.0019 0.0072 0.0227
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0283 0.2093 1
Trichomonas vaginalis r2r3-MYB transcription factor, putative 0.0019 0.0071 0.0224
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0283 0.2093 1
Brugia malayi Nuclear hormone receptor family member nhr-41 0.003 0.0156 0.1016
Brugia malayi latrophilin 2 splice variant baaae 0.0034 0.0181 0.1181
Plasmodium vivax thioredoxin reductase, putative 0.0038 0.0216 0.6722
Trichomonas vaginalis pc-MYB2, putative 0.0019 0.0071 0.0224
Brugia malayi CXXC zinc finger family protein 0.0029 0.0146 0.0948
Loa Loa (eye worm) hypothetical protein 0.0014 0.0033 0.0212
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0047 0.0281 0.1067
Treponema pallidum fructose-bisphosphate aldolase 0.0283 0.2093 0.2073
Mycobacterium ulcerans phenolpthiocerol synthesis type-I polyketide synthase PpsA 0.0019 0.0068 0.0062
Loa Loa (eye worm) glutathione reductase 0.0038 0.0216 0.1401
Loa Loa (eye worm) thioredoxin reductase 0.0038 0.0216 0.1401
Echinococcus multilocularis geminin 0.0347 0.2577 1
Schistosoma mansoni retinoid-x-receptor (RXR) 0.003 0.0156 0.0581
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0031 0.0159 0.0593
Trichomonas vaginalis MYB72, putative 0.0019 0.0071 0.0224
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0013 0.0025 0.0084
Schistosoma mansoni dihydrolipoamide dehydrogenase 0.0013 0.0025 0.007
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0013 0.0025 0.0084
Mycobacterium ulcerans polyketide synthase Pks9 0.0015 0.0039 0.0032
Loa Loa (eye worm) nuclear hormone receptor 0.0014 0.0033 0.0212
Mycobacterium tuberculosis Probable esterase LipL 0.0037 0.0205 0.0278
Schistosoma mansoni Tr4/Tr2 (homologue) 0.003 0.0156 0.0581
Mycobacterium tuberculosis Probable hydrolase 0.0037 0.0205 0.0278
Loa Loa (eye worm) hypothetical protein 0.0034 0.0181 0.1176
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.003 0.0156 0.1011
Echinococcus multilocularis thyroid hormone receptor alpha 0.003 0.0156 0.0603
Brugia malayi ecdysone receptor 0.0014 0.0033 0.0217
Mycobacterium tuberculosis Cytochrome P450 121 Cyp121 0.0011 0.0007 0.0001
Mycobacterium tuberculosis Probable lipase LipE 0.0037 0.0205 0.0278
Schistosoma mansoni hypothetical protein 0.0016 0.0043 0.0141
Mycobacterium tuberculosis Probable cytochrome P450 137 Cyp137 0.0011 0.0007 0.0001
Mycobacterium tuberculosis NADPH-dependent mycothiol reductase Mtr 0.0038 0.0216 0.0294
Loa Loa (eye worm) hypothetical protein 0.003 0.0156 0.1011
Loa Loa (eye worm) hypothetical protein 0.0155 0.1109 0.7215
Onchocerca volvulus Fatty acid synthase homolog 0.0048 0.029 0.1488
Loa Loa (eye worm) hypothetical protein 0.003 0.0156 0.1011
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.003 0.0156 0.0603
Loa Loa (eye worm) hypothetical protein 0.0037 0.0205 0.133
Echinococcus granulosus nuclear receptor subfamily 1 group D 0.0016 0.0047 0.0177
Trypanosoma cruzi hypothetical protein, conserved 0.0037 0.0205 0.0918
Trypanosoma cruzi cytochrome P450, putative 0.002 0.0076 0.0318
Mycobacterium tuberculosis Probable fructose-bisphosphate aldolase Fba 0.0138 0.0984 0.1367
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0014 0.0033 0.0126
Onchocerca volvulus 0.0029 0.0146 0.0651
Schistosoma mansoni thyroid hormone receptor 0.003 0.0156 0.0581
Toxoplasma gondii histone lysine methyltransferase SET1 0.0056 0.0353 0.1254
Loa Loa (eye worm) hypothetical protein 0.0016 0.0047 0.0297
Mycobacterium leprae PHENOLPTHIOCEROL SYNTHESIS TYPE-I POLYKETIDE SYNTHASE PPSD 0.0024 0.0108 0.0142
Loa Loa (eye worm) hypothetical protein 0.0049 0.0301 0.1953
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.0283 0.2093 1
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.003 0.0156 0.0581
Mycobacterium tuberculosis Phenyloxazoline synthase MbtB (phenyloxazoline synthetase) 0.0025 0.0114 0.0151
Mycobacterium leprae DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE 0.0097 0.0665 0.092
Mycobacterium tuberculosis Probable polyketide synthase Pks7 0.0026 0.0121 0.0161
Plasmodium vivax SET domain protein, putative 0.0031 0.0159 0.4724
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0013 0.0025 0.0084
Brugia malayi hypothetical protein 0.0014 0.0033 0.0217
Toxoplasma gondii hypothetical protein 0.0047 0.0285 0.101
Brugia malayi Cytochrome P450 family protein 0.002 0.0076 0.0492
Mycobacterium ulcerans beta-lactamase 0.0037 0.0205 0.0198
Brugia malayi Nuclear hormone receptor family member nhr-3 0.003 0.0156 0.1016
Mycobacterium tuberculosis Probable polyketide synthase Pks9 0.0015 0.0039 0.0047
Brugia malayi orphan nuclear receptor NR2E1 0.0014 0.0033 0.0217
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.003 0.0156 0.0603
Toxoplasma gondii type I fatty acid synthase, putative 0.0019 0.0068 0.0223
Mycobacterium tuberculosis Probable multifunctional mycocerosic acid synthase membrane-associated Mas 0.0026 0.0121 0.0161
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0211 0.1537 1
Loa Loa (eye worm) latrophilin receptor protein 2 0.0016 0.0043 0.0275
Brugia malayi beta-lactamase 0.0037 0.0205 0.1335
Loa Loa (eye worm) hypothetical protein 0.0014 0.0033 0.0212
Brugia malayi cytochrome P450 0.0011 0.0007 0.0045
Leishmania major mitochondrial DNA polymerase beta 0.0293 0.2166 1
Plasmodium vivax glutathione reductase, putative 0.0038 0.0216 0.6722
Echinococcus multilocularis cpg binding protein 0.0031 0.0158 0.0611
Echinococcus multilocularis retinoic acid receptor rxr beta a retinoic acid receptor rxr alpha a retinoic acid receptor rxr alpha 0.0014 0.0033 0.0126
Echinococcus granulosus nuclear receptor subfamily 4 group A 0.0014 0.0033 0.0126
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.003 0.0156 0.0603
Brugia malayi Pre-SET motif family protein 0.0211 0.1537 1
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.003 0.0156 0.1016
Mycobacterium tuberculosis Probable cytochrome P450 136 Cyp136 0.0011 0.0007 0.0001
Mycobacterium tuberculosis Probable cytochrome P450 128 Cyp128 0.0011 0.0007 0.0001
Leishmania major acetoin dehydrogenase e3 component-like protein 0.0013 0.0025 0.0084
Trichomonas vaginalis r2r3-MYB transcription factor, putative 0.0019 0.0071 0.0224
Treponema pallidum UDP-N-acetylglucosamine 1-carboxyvinyltransferase 0.1316 1 1
Brugia malayi Nuclear hormone receptor family member nhr-49 0.003 0.0156 0.1016
Loa Loa (eye worm) hypothetical protein 0.0016 0.0043 0.0275
Trypanosoma brucei PAB1-binding protein , putative 0.005 0.0309 0.14
Leishmania major 2-oxoglutarate dehydrogenase, e3 component, lipoamidedehydrogenase-like protein 0.0013 0.0025 0.0084
Loa Loa (eye worm) hypothetical protein 0.0014 0.0033 0.0212
Toxoplasma gondii pyruvate dehydrogenase complex subunit PDH-E3II 0.0013 0.0025 0.0066
Mycobacterium tuberculosis Probable cytochrome P450 124 Cyp124 0.0011 0.0007 0.0001
Toxoplasma gondii NADPH-glutathione reductase 0.0013 0.0025 0.0066
Wolbachia endosymbiont of Brugia malayi UDP-N-acetylglucosamine 1-carboxyvinyltransferase 0.1316 1 1
Trypanosoma cruzi DNA polymerase beta thumb, putative 0.0041 0.0239 0.1075
Brugia malayi conserved hypotetical protein 0.0014 0.0033 0.0217
Echinococcus multilocularis 0.0011 0.0007 0.0023
Leishmania major cytochrome p450-like protein 0.002 0.0076 0.0318
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0013 0.0025 0.0084
Mycobacterium ulcerans thioesterase TesA 0.0022 0.0093 0.0086
Mycobacterium ulcerans phenolpthiocerol synthesis type-I polyketide synthase PpsC 0.0026 0.0121 0.0114
Onchocerca volvulus 0.0155 0.1109 0.6234
Trypanosoma brucei dihydrolipoyl dehydrogenase 0.0013 0.0025 0.0084
Brugia malayi dihydrolipoyl dehydrogenase, mitochondrial precursor, putative 0.0013 0.0025 0.0163
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.003 0.0156 0.0603
Schistosoma mansoni RAR-like nuclear receptor 0.003 0.0156 0.0581
Echinococcus multilocularis dihydrolipoamide dehydrogenase 0.0013 0.0025 0.0094
Loa Loa (eye worm) CYP4Cod1 0.002 0.0076 0.0486
Mycobacterium ulcerans dihydrolipoamide dehydrogenase, LpdB 0.0013 0.0025 0.0018
Mycobacterium ulcerans hypothetical protein 0.0154 0.1105 0.1098
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0013 0.0025 0.0084
Loa Loa (eye worm) hypothetical protein 0.0037 0.0205 0.133
Echinococcus multilocularis transcription factor Dp 1 0.0039 0.0223 0.0863
Trichomonas vaginalis r2r3-MYB transcription factor, putative 0.0019 0.0071 0.0224
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0047 0.0281 0.1088
Mycobacterium tuberculosis Probable dehydrogenase 0.0087 0.059 0.0817
Echinococcus granulosus FTZ F1 alpha 0.003 0.0156 0.0603
Mycobacterium tuberculosis Probable reductase 0.0087 0.059 0.0817
Mycobacterium tuberculosis Probable polyketide synthase Pks1 0.0019 0.007 0.0089
Echinococcus granulosus nuclear receptor nhr 48 0.0014 0.0033 0.0126
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0047 0.0281 0.1067
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.005 0.0308 0.1394
Trypanosoma brucei hypothetical protein, conserved 0.0037 0.0205 0.0918
Brugia malayi MH2 domain containing protein 0.0116 0.0814 0.5296
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0016 0.0047 0.0154
Schistosoma mansoni nuclear receptor 0.0014 0.0033 0.0103
Loa Loa (eye worm) hypothetical protein 0.0014 0.0033 0.0212
Brugia malayi Steroid receptor seven-up type 2 0.003 0.0156 0.1016
Trypanosoma cruzi tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0068 0.0441 0.201
Brugia malayi beta-lactamase family protein 0.0037 0.0205 0.1335
Loa Loa (eye worm) hypothetical protein 0.0037 0.0205 0.133
Brugia malayi Beta-ketoacyl synthase, N-terminal domain containing protein 0.0024 0.0108 0.0704
Echinococcus granulosus Nuclear hormone receptor HR96 0.0014 0.0033 0.0126
Loa Loa (eye worm) hypothetical protein 0.0042 0.0246 0.1599
Schistosoma mansoni nuclear receptor nhr-48 0.0014 0.0033 0.0103
Schistosoma mansoni nuclear hormone receptor 0.0014 0.0033 0.0103
Mycobacterium leprae Probable polyketide synthase Pks1 0.0026 0.0121 0.0159
Trichomonas vaginalis pc-MYB2, putative 0.0019 0.0071 0.0224
Mycobacterium leprae PHENOLPTHIOCEROL SYNTHESIS TYPE-I POLYKETIDE SYNTHASE PPSE 0.0015 0.0039 0.0045
Schistosoma mansoni nuclear hormone receptor 0.003 0.0156 0.0581
Mycobacterium tuberculosis Probable cytochrome P450 143 Cyp143 0.0011 0.0007 0.0001
Brugia malayi nuclear receptor subfamily 1, group D, member 1, putative 0.0014 0.0033 0.0217
Onchocerca volvulus 0.0037 0.0205 0.0996
Trichomonas vaginalis C-MYB, putative 0.0019 0.0071 0.0224
Loa Loa (eye worm) hypothetical protein 0.003 0.0156 0.1011
Brugia malayi Thioredoxin reductase 0.0038 0.0216 0.1406
Mycobacterium leprae probable 3-phosphoshikimate 1-carboxyvinyl transferase AroA (5-ENOLPYRUVYLSHIKIMATE-3-PHOSPHATE SYNTHASE) (EPSP SYNTHASE) (EPSPS 0.0371 0.2764 0.3855
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0013 0.0025 0.0084
Onchocerca volvulus 0.0037 0.0205 0.0996
Loa Loa (eye worm) beta-lactamase 0.0037 0.0205 0.133
Plasmodium falciparum glutathione reductase 0.0038 0.0216 0.6722
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0063 0.0403 0.1541
Onchocerca volvulus 0.0037 0.0205 0.0996
Brugia malayi nuclear receptor NHR-67 0.0014 0.0033 0.0217
Schistosoma mansoni hypothetical protein 0.0023 0.0097 0.0349
Echinococcus granulosus GPCR family 2 0.0016 0.0043 0.0164
Giardia lamblia Fructose-bisphosphate aldolase 0.0283 0.2093 1
Loa Loa (eye worm) tyrosyl-DNA phosphodiesterase 0.0068 0.0441 0.2865
Mycobacterium leprae PROBABLE UDP-N-ACETYLGLUCOSAMINE 1-CARBOXYVINYLTRANSFERASE MURA 0.0945 0.7159 1
Trypanosoma brucei mitochondrial DNA polymerase beta 0.0293 0.2166 1
Brugia malayi oxidoreductase, zinc-binding dehydrogenase family protein 0.0048 0.029 0.1888
Mycobacterium tuberculosis Possible cytochrome P450 126 Cyp126 0.0011 0.0007 0.0001
Mycobacterium ulcerans cytochrome P450 185A4 Cyp185A4 0.002 0.0076 0.0069
Mycobacterium leprae PROBABLE NADH DEHYDROGENASE NDH 0.0087 0.059 0.0816
Toxoplasma gondii type I fatty acid synthase, putative 0.0026 0.0121 0.0413
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0013 0.0025 0.0084
Toxoplasma gondii thioredoxin reductase 0.0038 0.0216 0.0758
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.003 0.0156 0.1011
Brugia malayi photoreceptor-specific nuclear receptor 0.003 0.0156 0.1016
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.003 0.0156 0.0603
Trichomonas vaginalis penicillin-binding protein, putative 0.0037 0.0205 0.0871
Trichomonas vaginalis D-aminoacylase, putative 0.0037 0.0205 0.0871
Loa Loa (eye worm) transcription factor SMAD2 0.0116 0.0814 0.5293
Brugia malayi ecdysteroid receptor 0.003 0.0156 0.1016
Mycobacterium ulcerans phenolpthiocerol synthesis type-I polyketide synthase PpsD 0.0024 0.0108 0.0101
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.003 0.0156 0.0603
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0047 0.0281 0.1088
Loa Loa (eye worm) hypothetical protein 0.003 0.0156 0.1011
Brugia malayi AMP-binding enzyme family protein 0.0025 0.0114 0.074
Schistosoma mansoni nuclear hormone receptor superfamily protein-related 0.0014 0.0033 0.0103
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0029 0.0146 0.0563
Schistosoma mansoni thyroid hormone receptor 0.003 0.0156 0.0581
Brugia malayi Pre-SET motif family protein 0.0031 0.0159 0.1036
Mycobacterium leprae PROBABLE THIOESTERASE TESA 0.0022 0.0093 0.0121
Loa Loa (eye worm) hypothetical protein 0.0016 0.0047 0.0297
Echinococcus granulosus tyrosyl DNA phosphodiesterase 1 0.0068 0.0441 0.1708
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0283 0.2093 1
Mycobacterium tuberculosis Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB 0.0087 0.059 0.0817
Trypanosoma cruzi hypothetical protein, conserved 0.0037 0.0205 0.0918
Schistosoma mansoni hypothetical protein 0.0034 0.0181 0.0679
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.003 0.0156 0.0581
Mycobacterium tuberculosis Probable cytochrome P450 130 Cyp130 0.0011 0.0007 0.0001
Mycobacterium tuberculosis Probable soluble pyridine nucleotide transhydrogenase SthA (STH) (NAD(P)(+) transhydrogenase [B-specific]) (nicotinamide nucleot 0.0013 0.0025 0.0027
Loa Loa (eye worm) fatty acid synthase 0.0026 0.0124 0.0804
Schistosoma mansoni ecdysone-induced protein 78c (dr-78) 0.0016 0.0047 0.0154
Loa Loa (eye worm) cytochrome P450 family protein 0.002 0.0076 0.0486
Mycobacterium ulcerans Type I modular polyketide synthase 0.0024 0.0108 0.0101
Echinococcus granulosus geminin 0.0347 0.2577 1
Echinococcus granulosus thioredoxin glutathione reductase 0.0039 0.022 0.085
Brugia malayi Nuclear hormone receptor family member nhr-25 0.003 0.0156 0.1016
Mycobacterium leprae Polyketide synthase Pks13 0.0037 0.0209 0.0282
Loa Loa (eye worm) hypothetical protein 0.0014 0.0033 0.0212
Mycobacterium tuberculosis Polyketide synthase Pks13 0.0037 0.0209 0.0283
Brugia malayi tailless protein 0.0014 0.0033 0.0217
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0031 0.0159 0.0593
Mycobacterium leprae Probable lipase LipE 0.0037 0.0205 0.0277
Brugia malayi Nuclear hormone receptor family member nhr-1 0.003 0.0156 0.1016
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0016 0.0043 0.0164
Mycobacterium ulcerans phenolpthiocerol synthesis type-I polyketide synthase PpsE 0.0015 0.0039 0.0032
Schistosoma mansoni cpg binding protein 0.0031 0.0158 0.0589
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0283 0.2093 1
Mycobacterium ulcerans multifunctional mycocerosic acid synthase membrane-associated Mas 0.0026 0.0121 0.0114
Loa Loa (eye worm) hypothetical protein 0.0016 0.0047 0.0297
Mycobacterium ulcerans UDP-N-acetylglucosamine 1-carboxyvinyltransferase 0.1316 1 1
Loa Loa (eye worm) hypothetical protein 0.0014 0.0033 0.0212
Echinococcus multilocularis nuclear receptor subfamily 4 group A 0.0014 0.0033 0.0126
Mycobacterium ulcerans fructose-bisphosphate aldolase 0.0138 0.0984 0.0977
Loa Loa (eye worm) hypothetical protein 0.0014 0.0033 0.0212
Mycobacterium leprae PHENOLPTHIOCEROL SYNTHESIS TYPE-I POLYKETIDE SYNTHASE PPSA 0.0024 0.0108 0.0142
Mycobacterium leprae Probable multifunctional mycocerosic acid synthase membrane associated enzyme Mas 0.0026 0.0121 0.0159
Echinococcus granulosus ecdysone induced protein 78C 0.003 0.0156 0.0603
Plasmodium vivax ataxin-2 like protein, putative 0.005 0.0309 1
Echinococcus granulosus dihydrolipoamide dehydrogenase 0.0013 0.0025 0.0094
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0013 0.0025 0.0084
Echinococcus multilocularis nuclear receptor nhr 48 0.0014 0.0033 0.0126
Mycobacterium tuberculosis Possible penicillin-binding protein 0.0235 0.1721 0.2398
Onchocerca volvulus Bile acid receptor homolog 0.003 0.0156 0.0711
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0037 0.0205 0.0771
Mycobacterium tuberculosis Probable cytochrome P450 123 Cyp123 0.0011 0.0007 0.0001
Mycobacterium ulcerans phenolpthiocerol synthesis type-I polyketide synthase PpsB 0.0019 0.0068 0.0062
Mycobacterium leprae Probable fructose bisphosphate aldolase Fba 0.0138 0.0984 0.1365
Trypanosoma cruzi trypanothione reductase, putative 0.0038 0.0216 0.0969
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0031 0.0159 0.0615
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0049 0.0301 0.1957
Mycobacterium tuberculosis NAD(P)H quinone reductase LpdA 0.0097 0.0665 0.0921
Mycobacterium tuberculosis Conserved hypothetical protein 0.0154 0.1105 0.1536
Loa Loa (eye worm) hypothetical protein 0.005 0.0309 0.2007
Brugia malayi nuclear hormone receptor family member odr-7 0.0014 0.0033 0.0217
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.003 0.0156 0.1011
Mycobacterium tuberculosis Probable cytochrome P450 138 Cyp138 0.0011 0.0007 0.0001
Brugia malayi Nuclear hormone receptor-like 1 0.003 0.0156 0.1016
Trichomonas vaginalis r2r3-MYB transcription factor, putative 0.0019 0.0072 0.0227
Echinococcus granulosus Ataxin 2 N terminaldomain containing protein 0.0023 0.0097 0.0372
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0031 0.0159 0.0615
Brugia malayi nuclear hormone receptor 0.0014 0.0033 0.0217
Toxoplasma gondii ABC1 family protein 0.0037 0.0205 0.0719
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.003 0.0156 0.1011
Echinococcus granulosus retinoic acid receptor rxr beta a 0.003 0.0156 0.0603
Loa Loa (eye worm) nuclear receptor nhr-7B 0.0014 0.0033 0.0212
Mycobacterium tuberculosis Probable NADH dehydrogenase Ndh 0.0087 0.059 0.0817
Schistosoma mansoni steroid hormone receptor ad4bp 0.003 0.0156 0.0581
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.003 0.0156 0.1011
Trypanosoma cruzi mitochondrial DNA polymerase beta, putative 0.0293 0.2166 1
Echinococcus granulosus beta LACTamase domain containing family member 0.0037 0.0205 0.0793
Trypanosoma brucei DNA polymerase beta thumb, putative 0.0041 0.0239 0.1075
Echinococcus granulosus thyroid hormone receptor alpha 0.0014 0.0033 0.0126
Trypanosoma cruzi cytochrome P450, putative 0.002 0.0076 0.0318
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.0037 0.0205 0.0278
Brugia malayi Calcitonin receptor-like protein seb-1 0.0049 0.0301 0.1957
Echinococcus multilocularis tyrosyl DNA phosphodiesterase 1 0.0068 0.0441 0.1708
Brugia malayi Nuclear hormone receptor family member nhr-31 0.003 0.0156 0.1016
Schistosoma mansoni retinoic acid receptor RXR 0.003 0.0156 0.0581
Onchocerca volvulus Protein ultraspiracle homolog 0.003 0.0156 0.0711
Mycobacterium tuberculosis Putative ferredoxin reductase 0.0087 0.059 0.0817
Brugia malayi Nuclear hormone receptor family member nhr-19 0.003 0.0156 0.1016
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0049 0.0301 0.1953
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0047 0.0281 0.1826
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0016 0.0043 0.0164
Trypanosoma cruzi mitochondrial DNA polymerase beta, putative 0.0293 0.2166 1
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.003 0.0156 0.0603
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.0283 0.2093 1
Mycobacterium tuberculosis Probable membrane bound polyketide synthase Pks6 0.0037 0.0209 0.0283
Loa Loa (eye worm) cytochrome P450 0.0011 0.0007 0.0039
Loa Loa (eye worm) hypothetical protein 0.0037 0.0205 0.133
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.0037 0.0205 0.0198
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0283 0.2093 1
Mycobacterium tuberculosis Probable cytochrome P450 139 Cyp139 0.0011 0.0007 0.0001
Loa Loa (eye worm) hypothetical protein 0.003 0.0156 0.1011
Brugia malayi Nuclear hormone receptor family member nhr-19 0.003 0.0156 0.1016
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0031 0.0159 0.0552
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0031 0.0159 0.0593
Trichomonas vaginalis r2r3-MYB transcription factor, putative 0.0019 0.0072 0.0227
Leishmania major trypanothione reductase 0.0038 0.0216 0.0969
Mycobacterium tuberculosis Conserved protein 0.0037 0.0205 0.0278
Brugia malayi Tyrosyl-DNA phosphodiesterase family protein 0.0068 0.0441 0.2869
Echinococcus granulosus cytochrome P450 2K1 0.0011 0.0007 0.0023
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.003 0.0156 0.0581
Brugia malayi glutathione reductase 0.0038 0.0216 0.1406
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0013 0.0025 0.0084
Brugia malayi Nuclear hormone receptor family member nhr-14 0.003 0.0156 0.1016
Brugia malayi Cytochrome P450 family protein 0.0011 0.0007 0.0045
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0283 0.2093 1
Toxoplasma gondii shikimate dehydrogenase substrate binding domain-containing protein 0.0371 0.2764 1
Mycobacterium tuberculosis Conserved protein 0.0037 0.0205 0.0278
Schistosoma mansoni hepatocyte nuclear factor 4-alpha (hnf-4-alpha) 0.0014 0.0033 0.0103
Toxoplasma gondii LsmAD domain-containing protein 0.005 0.0309 0.1096
Trichomonas vaginalis C-MYB, putative 0.0019 0.0071 0.0224
Mycobacterium tuberculosis Polyketide synthase Pks12 0.0026 0.0121 0.0161
Plasmodium falciparum ataxin-2 like protein, putative 0.005 0.0309 1
Schistosoma mansoni hypothetical protein 0.0016 0.0043 0.0141
Loa Loa (eye worm) nuclear receptor NHR-67 0.0014 0.0033 0.0212
Mycobacterium ulcerans esterase/lipase LipP 0.0037 0.0205 0.0198
Loa Loa (eye worm) hypothetical protein 0.0014 0.0033 0.0212
Mycobacterium tuberculosis Probable cytochrome P450 144 Cyp144 0.0011 0.0007 0.0001
Loa Loa (eye worm) cytochrome P450 family protein 0.003 0.0156 0.1013
Mycobacterium tuberculosis Probable conserved lipoprotein 0.0037 0.0205 0.0278
Brugia malayi Cytochrome P450 family protein 0.002 0.0076 0.0492
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.003 0.0156 0.0603
Brugia malayi hypothetical protein 0.0155 0.1109 0.7217
Echinococcus multilocularis FTZ F1 alpha 0.003 0.0156 0.0603
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0013 0.0025 0.0084
Onchocerca volvulus 0.0046 0.0278 0.1415
Brugia malayi hypothetical protein 0.0033 0.0173 0.1123
Mycobacterium tuberculosis Probable oxidoreductase 0.0097 0.0665 0.0921
Brugia malayi steroid hormone receptor 0.003 0.0156 0.1016
Loa Loa (eye worm) cytochrome P450 family protein 0.002 0.0076 0.0486
Trypanosoma cruzi PAB1-binding protein , putative 0.005 0.0309 0.14
Echinococcus granulosus transcription factor Dp 1 0.0039 0.0223 0.0863
Mycobacterium ulcerans polyketide synthase 0.0026 0.0121 0.0114
Brugia malayi beta-lactamase family protein 0.0037 0.0205 0.1335
Mycobacterium ulcerans polyketide synthase Pks13 0.0037 0.0209 0.0202
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0283 0.2093 1
Brugia malayi hypothetical protein 0.0016 0.0047 0.0303
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0041 0.0239 0.1075
Mycobacterium tuberculosis Probable cytochrome P450 monooxygenase 142 Cyp142 0.0011 0.0007 0.0001
Mycobacterium ulcerans 3-phosphoshikimate 1-carboxyvinyltransferase 0.0371 0.2764 0.2759
Schistosoma mansoni hypothetical protein 0.0347 0.2577 1
Loa Loa (eye worm) hypothetical protein 0.0014 0.0033 0.0212
Toxoplasma gondii AMP-binding enzyme domain-containing protein 0.0013 0.0026 0.0071
Loa Loa (eye worm) steroid hormone receptor 0.003 0.0156 0.1011
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.003 0.0156 0.0711
Brugia malayi Nuclear hormone receptor E75 0.0014 0.0033 0.0217
Echinococcus multilocularis thioredoxin glutathione reductase 0.0039 0.022 0.085
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0037 0.0205 0.133
Loa Loa (eye worm) hypothetical protein 0.0037 0.0205 0.133
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.0037 0.0205 0.0278
Loa Loa (eye worm) hypothetical protein 0.0016 0.0047 0.0297
Mycobacterium ulcerans Type I modular polyketide synthase 0.0024 0.0108 0.0101
Loa Loa (eye worm) hypothetical protein 0.003 0.0156 0.1011
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0016 0.0043 0.028
Echinococcus multilocularis GPCR, family 2 0.0016 0.0043 0.0164
Brugia malayi nuclear receptor RXR 0.0014 0.0033 0.0217
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0013 0.0025 0.0084
Brugia malayi Nuclear hormone receptor-like 1 0.0016 0.0047 0.0303
Plasmodium falciparum ataxin-2 like protein, putative 0.005 0.0309 1
Brugia malayi Nuclear hormone receptor family member nhr-40 0.003 0.0156 0.1016
Trichomonas vaginalis r2r3-MYB transcription factor, putative 0.0019 0.0071 0.0224
Mycobacterium leprae conserved hypothetical protein 0.0037 0.0205 0.0277
Brugia malayi hypothetical protein 0.005 0.0309 0.2012
Mycobacterium ulcerans lipase LipD 0.0037 0.0205 0.0198
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0037 0.0205 0.1335
Trichomonas vaginalis r2r3-MYB transcription factor, putative 0.0019 0.0071 0.0224
Echinococcus granulosus histone lysine methyltransferase setb 0.0031 0.0159 0.0615
Loa Loa (eye worm) hypothetical protein 0.0037 0.0205 0.133
Trichomonas vaginalis r2r3-MYB transcription factor, putative 0.0019 0.0071 0.0224
Loa Loa (eye worm) CXXC zinc finger family protein 0.0029 0.0146 0.0943
Leishmania major mitochondrial DNA polymerase beta-PAK, putative 0.0139 0.0985 0.453
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0047 0.0281 0.183
Mycobacterium ulcerans polyketide synthase 0.0024 0.0108 0.0101
Schistosoma mansoni hypothetical protein 0.0016 0.0043 0.0141
Plasmodium falciparum thioredoxin reductase 0.0038 0.0216 0.6722
Trichomonas vaginalis D-aminoacylase, putative 0.0037 0.0205 0.0871
Onchocerca volvulus 0.0025 0.0114 0.0465
Trypanosoma cruzi trypanothione reductase, putative 0.0013 0.0025 0.0084
Onchocerca volvulus 0.003 0.0156 0.0711
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.003 0.0156 0.1016
Brugia malayi hypothetical protein 0.0014 0.0033 0.0217
Loa Loa (eye worm) DR-78 0.0014 0.0033 0.0212
Loa Loa (eye worm) hypothetical protein 0.003 0.0156 0.1011
Mycobacterium tuberculosis Probable cytochrome P450 140 Cyp140 0.0011 0.0007 0.0001
Trichomonas vaginalis penicillin-binding protein, putative 0.0037 0.0205 0.0871
Trichomonas vaginalis D-aminoacylase, putative 0.0037 0.0205 0.0871
Brugia malayi Cytochrome P450 family protein 0.003 0.0156 0.1018
Loa Loa (eye worm) hypothetical protein 0.0014 0.0033 0.0212
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0047 0.0281 0.1088
Toxoplasma gondii beta-ketoacyl synthase, N-terminal domain-containing protein 0.0017 0.0056 0.0177
Echinococcus granulosus Nuclear hormone receptor HR96 0.0014 0.0033 0.0126
Leishmania major tyrosyl-DNA phosphodiesterase 1 0.0068 0.0441 0.201
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0013 0.0025 0.0084
Mycobacterium tuberculosis Probable polyketide synthase Pks5 0.0026 0.0121 0.0161
Mycobacterium tuberculosis Probable thioesterase TesA 0.0022 0.0093 0.0122
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.003 0.0156 0.1011
Trichomonas vaginalis MYB3r3, putative 0.0019 0.0071 0.0224
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.003 0.0156 0.0603
Mycobacterium tuberculosis Probable UDP-N-acetylglucosamine 1-carboxyvinyltransferase MurA 0.0945 0.7159 1
Chlamydia trachomatis phosphoshikimate 1-carboxyl vinyltransferase 0.0371 0.2764 0.2746
Trypanosoma brucei trypanothione reductase 0.0038 0.0216 0.0969
Schistosoma mansoni cpg binding protein 0.0029 0.0146 0.054
Schistosoma mansoni hypothetical protein 0.0016 0.0043 0.0141
Trypanosoma brucei dihydrolipoamide dehydrogenase, point mutation 0.0013 0.0025 0.0084
Schistosoma mansoni hypothetical protein 0.0347 0.2577 1
Entamoeba histolytica tyrosyl-DNA phosphodiesterase, putative 0.0068 0.0441 0.1828
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0047 0.0281 0.1067
Mycobacterium ulcerans flavoprotein disulfide reductase 0.0013 0.0025 0.0018
Mycobacterium tuberculosis Probable lipase LipD 0.0037 0.0205 0.0278
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0016 0.0043 0.0164
Loa Loa (eye worm) MH2 domain-containing protein 0.0116 0.0814 0.5293
Mycobacterium tuberculosis Conserved protein 0.0037 0.0205 0.0278
Brugia malayi Nuclear hormone receptor E75 0.0014 0.0033 0.0217
Brugia malayi nuclear receptor RXR 0.0016 0.0047 0.0303
Mycobacterium ulcerans dihydrolipoamide dehydrogenase 0.0013 0.0025 0.0018
Trichomonas vaginalis set domain proteins, putative 0.024 0.1759 0.8382
Brugia malayi Nuclear hormone receptor family member nhr-25 0.003 0.0156 0.1016
Mycobacterium tuberculosis Cytochrome P450 51 Cyp51 (CYPL1) (P450-L1A1) (sterol 14-alpha demethylase) (lanosterol 14-alpha demethylase) (P450-14DM) 0.0011 0.0007 0.0001
Trypanosoma brucei tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0068 0.0441 0.201
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.003 0.0156 0.0581
Echinococcus multilocularis beta LACTamase domain containing family member 0.0037 0.0205 0.0793
Brugia malayi Nuclear hormone receptor-like 1 0.0016 0.0047 0.0303
Schistosoma mansoni zinc finger protein 0.0014 0.0033 0.0103
Schistosoma mansoni coup transcription factor 0.003 0.0156 0.0581
Echinococcus multilocularis Ataxin 2, N terminal,domain containing protein 0.0023 0.0097 0.0372
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0016 0.0043 0.0164
Onchocerca volvulus 0.024 0.1759 1
Mycobacterium tuberculosis Probable membrane NADH dehydrogenase NdhA 0.0087 0.059 0.0817
Mycobacterium tuberculosis Probable cytochrome P450 141 Cyp141 0.0011 0.0007 0.0001
Loa Loa (eye worm) hypothetical protein 0.003 0.0156 0.1011
Echinococcus multilocularis ecdysone induced protein 78C 0.003 0.0156 0.0603
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0014 0.0033 0.0126
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0014 0.0033 0.0126
Echinococcus granulosus nuclear receptor 2DBD gamma 0.003 0.0156 0.0603
Mycobacterium tuberculosis Probable cytochrome P450 125 Cyp125 0.0011 0.0007 0.0001
Trypanosoma cruzi PAB1-binding protein , putative 0.005 0.0309 0.14
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0047 0.0281 0.1088
Leishmania major hypothetical protein, conserved 0.0037 0.0205 0.0918
Loa Loa (eye worm) hypothetical protein 0.0014 0.0033 0.0212
Mycobacterium tuberculosis Polyketide synthase Pks2 0.0026 0.0121 0.0161
Loa Loa (eye worm) hypothetical protein 0.0031 0.0159 0.1031
Echinococcus granulosus nuclear receptor 2DBD gamma 0.003 0.0156 0.0603
Schistosoma mansoni nuclear hormone receptor 0.0014 0.0033 0.0103
Mycobacterium ulcerans Type I modular polyketide synthase 0.0024 0.0108 0.0101
Mycobacterium ulcerans hypothetical protein 0.0037 0.0205 0.0198
Trypanosoma cruzi DNA polymerase beta thumb, putative 0.0041 0.0239 0.1075
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0139 0.0985 0.453
Toxoplasma gondii Myb family DNA-binding domain-containing protein 0.0019 0.0072 0.0236
Brugia malayi nuclear hormone receptor 0.003 0.0156 0.1016
Schistosoma mansoni cpg binding protein 0.0031 0.0158 0.0589
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0014 0.0033 0.0126
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.003 0.0156 0.1011
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0283 0.2093 1
Loa Loa (eye worm) hypothetical protein 0.0014 0.0033 0.0212
Leishmania major hypothetical protein, conserved 0.005 0.0309 0.14

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

No literature references available for this target.

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