Detailed information for compound 1327198

Basic information

Technical information
  • TDR Targets ID: 1327198
  • Name: 2-nitro-5-pyrrolidin-1-ylaniline
  • MW: 207.229 | Formula: C10H13N3O2
  • H donors: 1 H acceptors: 2 LogP: 2.23 Rotable bonds: 2
    Rule of 5 violations (Lipinski): 1
  • SMILES: [O-][N+](=O)c1ccc(cc1N)N1CCCC1
  • InChi: 1S/C10H13N3O2/c11-9-7-8(12-5-1-2-6-12)3-4-10(9)13(14)15/h3-4,7H,1-2,5-6,11H2
  • InChiKey: KZZVVXNPKKQIJZ-UHFFFAOYSA-N  


Substructure search Similarity search

Network

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Synonyms

  • 2-nitro-5-pyrrolidin-1-yl-aniline
  • 2-nitro-5-1-pyrrolidinylaniline
  • (2-nitro-5-pyrrolidin-1-yl-phenyl)amine
  • 4Z-0700
  • ZINC03883989
  • MLS000687263
  • SMR000283981
  • Oprea1_697209
  • 2-Nitro-5-pyrrolidin-1-yl-phenylamine
  • BAS 00253667

Targets

Known targets for this compound

Species Target name Source Bibliographic reference
Homo sapiens nuclear factor, erythroid 2-like 2 Starlite/ChEMBL No references
Homo sapiens lamin A/C Starlite/ChEMBL No references
Homo sapiens ATPase family, AAA domain containing 5 Starlite/ChEMBL No references
Homo sapiens APEX nuclease (multifunctional DNA repair enzyme) 1 Starlite/ChEMBL No references

Predicted pathogen targets for this compound

By orthology
Species Potential target Known druggable target/s Ortholog Group
Brugia malayi exodeoxyribonuclease III family protein Get druggable targets OG5_126768 All targets in OG5_126768
Schistosoma mansoni intermediate filament proteins Get druggable targets OG5_128723 All targets in OG5_128723
Onchocerca volvulus Get druggable targets OG5_128723 All targets in OG5_128723
Schistosoma mansoni ap endonuclease Get druggable targets OG5_126768 All targets in OG5_126768
Entamoeba histolytica exodeoxyribonuclease III, putative Get druggable targets OG5_126768 All targets in OG5_126768
Plasmodium falciparum AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative Get druggable targets OG5_126768 All targets in OG5_126768
Schistosoma japonicum ko:K07611 lamin, putative Get druggable targets OG5_128723 All targets in OG5_128723
Mycobacterium ulcerans exodeoxyribonuclease III protein XthA Get druggable targets OG5_126768 All targets in OG5_126768
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative Get druggable targets OG5_126768 All targets in OG5_126768
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_128723 All targets in OG5_128723
Plasmodium berghei AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative Get druggable targets OG5_126768 All targets in OG5_126768
Giardia lamblia Endonuclease/Exonuclease/phosphatase Get druggable targets OG5_126768 All targets in OG5_126768
Trichomonas vaginalis ap endonuclease, putative Get druggable targets OG5_126768 All targets in OG5_126768
Trypanosoma brucei gambiense apurinic/apyrimidinic endonuclease, putative Get druggable targets OG5_126768 All targets in OG5_126768
Loa Loa (eye worm) intermediate filament tail domain-containing protein Get druggable targets OG5_128723 All targets in OG5_128723
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase Get druggable targets OG5_126768 All targets in OG5_126768
Schistosoma japonicum Lamin-C, putative Get druggable targets OG5_128723 All targets in OG5_128723
Mycobacterium tuberculosis Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) Get druggable targets OG5_126768 All targets in OG5_126768
Echinococcus granulosus intermediate filament protein Get druggable targets OG5_128723 All targets in OG5_128723
Candida albicans similar to S. cerevisiae APN2 (YBL019W) DNA repair apurinic/apyrimidinic endonuclease Get druggable targets OG5_126768 All targets in OG5_126768
Schistosoma japonicum ko:K10771 AP endonuclease 1, putative Get druggable targets OG5_126768 All targets in OG5_126768
Trypanosoma cruzi apurinic/apyrimidinic endonuclease Get druggable targets OG5_126768 All targets in OG5_126768
Schistosoma japonicum expressed protein Get druggable targets OG5_128723 All targets in OG5_128723
Plasmodium yoelii putative AP endonuclease-related Get druggable targets OG5_126768 All targets in OG5_126768
Trypanosoma congolense apurinic/apyrimidinic endonuclease, putative Get druggable targets OG5_126768 All targets in OG5_126768
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_128723 All targets in OG5_128723
Schistosoma mansoni ap endonuclease Get druggable targets OG5_126768 All targets in OG5_126768
Onchocerca volvulus Get druggable targets OG5_128723 All targets in OG5_128723
Treponema pallidum exodeoxyribonuclease (exoA) Get druggable targets OG5_126768 All targets in OG5_126768
Brugia malayi Intermediate filament tail domain containing protein Get druggable targets OG5_128723 All targets in OG5_128723
Echinococcus granulosus lamin dm0 Get druggable targets OG5_128723 All targets in OG5_128723
Wolbachia endosymbiont of Brugia malayi exonuclease III Get druggable targets OG5_126768 All targets in OG5_126768
Plasmodium knowlesi AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative Get druggable targets OG5_126768 All targets in OG5_126768
Leishmania donovani apurinic/apyrimidinic endonuclease-redox protein Get druggable targets OG5_126768 All targets in OG5_126768
Echinococcus multilocularis lamin dm0 Get druggable targets OG5_128723 All targets in OG5_128723
Echinococcus multilocularis lamin Get druggable targets OG5_128723 All targets in OG5_128723
Trichomonas vaginalis ap endonuclease, putative Get druggable targets OG5_126768 All targets in OG5_126768
Toxoplasma gondii exonuclease III APE Get druggable targets OG5_126768 All targets in OG5_126768
Schistosoma japonicum Intermediate filament protein ifa-1, putative Get druggable targets OG5_128723 All targets in OG5_128723
Loa Loa (eye worm) exodeoxyribonuclease III family protein Get druggable targets OG5_126768 All targets in OG5_126768
Schistosoma japonicum expressed protein Get druggable targets OG5_128723 All targets in OG5_128723
Neospora caninum hypothetical protein Get druggable targets OG5_126768 All targets in OG5_126768
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase Get druggable targets OG5_126768 All targets in OG5_126768
Candida albicans similar to S. cerevisiae APN2 (YBL019W) DNA repair apurinic/apyrimidinic endonuclease Get druggable targets OG5_126768 All targets in OG5_126768
Echinococcus granulosus lamin Get druggable targets OG5_128723 All targets in OG5_128723
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_128723 All targets in OG5_128723
Plasmodium vivax AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative Get druggable targets OG5_126768 All targets in OG5_126768
Leishmania major apurinic/apyrimidinic endonuclease-redox protein Get druggable targets OG5_126768 All targets in OG5_126768
Loa Loa (eye worm) intermediate filament protein Get druggable targets OG5_128723 All targets in OG5_128723
Echinococcus multilocularis atpase aaa+ type core atpase aaa type core Get druggable targets OG5_139225 All targets in OG5_139225
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_128723 All targets in OG5_128723
Schistosoma japonicum ko:K10772 AP endonuclease 2, putative Get druggable targets OG5_126768 All targets in OG5_126768
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative Get druggable targets OG5_126768 All targets in OG5_126768
Echinococcus multilocularis cytoplasmic intermediate filament protein Get druggable targets OG5_128723 All targets in OG5_128723
Echinococcus multilocularis musashi Get druggable targets OG5_128723 All targets in OG5_128723
Theileria parva hypothetical protein Get druggable targets OG5_126768 All targets in OG5_126768
Brugia malayi intermediate filament protein Get druggable targets OG5_128723 All targets in OG5_128723
Schistosoma japonicum DNA-(apurinic or apyrimidinic site) lyase 2, putative Get druggable targets OG5_126768 All targets in OG5_126768
Schistosoma mansoni lamin Get druggable targets OG5_128723 All targets in OG5_128723
Schistosoma japonicum DNA-(apurinic or apyrimidinic site) lyase 2, putative Get druggable targets OG5_126768 All targets in OG5_126768
Cryptosporidium hominis dna-(apurinic or apyrimidinic site) lyase Get druggable targets OG5_126768 All targets in OG5_126768
Leishmania mexicana apurinic/apyrimidinic endonuclease-redox protein,AP-endonuclease Get druggable targets OG5_126768 All targets in OG5_126768
Schistosoma mansoni lamin Get druggable targets OG5_128723 All targets in OG5_128723
Leishmania infantum apurinic/apyrimidinic endonuclease-redox protein Get druggable targets OG5_126768 All targets in OG5_126768
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_128723 All targets in OG5_128723
Echinococcus granulosus cytoplasmic intermediate filament protein Get druggable targets OG5_128723 All targets in OG5_128723
Leishmania braziliensis apurinic/apyrimidinic endonuclease-redox protein Get druggable targets OG5_126768 All targets in OG5_126768
Cryptosporidium parvum conserved hypothetical protein Get druggable targets OG5_126768 All targets in OG5_126768
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 0.0031 0.0086 0.0147
Schistosoma mansoni voltage-gated potassium channel 0.002 0.0011 0.0016
Plasmodium vivax lysine--tRNA ligase, putative 0.0022 0.0028 0.0096
Brugia malayi MH2 domain containing protein 0.0049 0.0217 0.0217
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.002 0.0011 0.0016
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 4 0.0022 0.0027 0.0039
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0022 0.0027 0.0103
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.002 0.0011 0.0016
Onchocerca volvulus 0.0033 0.0101 0.0157
Trypanosoma brucei glucose transporter, putative 0.0031 0.0089 0.058
Trichomonas vaginalis conserved hypothetical protein 0.0022 0.0027 0.0103
Trypanosoma brucei ubiquitin carboxyl-terminal hydrolase, putative 0.0022 0.0027 0.0115
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0845 0.5866 0.8603
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0845 0.5866 0.8634
Schistosoma mansoni GTP-binding protein alpha subunit gna 0.0036 0.0127 0.0187
Loa Loa (eye worm) MH1 domain-containing protein 0.0049 0.0217 0.0217
Brugia malayi Egg laying defective protein 4 0.0022 0.0025 0.0025
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 4 0.0022 0.0027 0.0039
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 24 0.0022 0.0027 0.0039
Echinococcus multilocularis guanine nucleotide binding protein subunit 0.0036 0.0127 0.0187
Schistosoma mansoni hypothetical protein 0.0169 0.1068 0.1572
Trypanosoma cruzi apurinic/apyrimidinic endonuclease 0.0023 0.0031 0.0147
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0022 0.0027 0.0103
Schistosoma mansoni ubiquitin-specific peptidase 48 (C19 family) 0.0022 0.0027 0.0039
Loa Loa (eye worm) ubiquitin carboxyl-terminal hydrolase 0.0022 0.0027 0.0027
Trypanosoma cruzi isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0079 0.0428 0.3094
Toxoplasma gondii calcium-dependent protein kinase CDPK3 0.0031 0.0087 0.0406
Brugia malayi ubiquitin carboxyl-terminal hydrolase 46 0.0022 0.0027 0.0027
Loa Loa (eye worm) hypothetical protein 0.002 0.0011 0.0011
Toxoplasma gondii ubiquitin carboxyl-terminal hydrolase 0.0022 0.0027 0.0083
Mycobacterium tuberculosis Probable transcriptional regulatory protein Cmr 0.002 0.0011 0.0051
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0845 0.5866 1
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0022 0.0027 0.0103
Brugia malayi regulator of G-protein signaling egl-10 0.0045 0.0192 0.0192
Loa Loa (eye worm) hypothetical protein 0.002 0.0011 0.0011
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 7 0.0022 0.0027 0.0039
Plasmodium falciparum calcium-dependent protein kinase 5 0.0031 0.0087 0.0301
Trypanosoma cruzi ubiquitin hydrolase, putative 0.0022 0.0027 0.0115
Brugia malayi RNA recognition motif domain containing protein 0.0384 0.2597 0.2597
Echinococcus granulosus solute carrier family 2 facilitated glucose 0.01 0.0577 0.0984
Plasmodium falciparum calcium-dependent protein kinase 3 0.0031 0.0087 0.0301
Plasmodium vivax ubiquitin carboxyl-terminal hydrolase 1, putative 0.0022 0.0027 0.0092
Onchocerca volvulus 0.0036 0.0127 0.0198
Toxoplasma gondii ubiquitin carboxyl-terminal hydrolase 0.0022 0.0027 0.0083
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0022 0.0027 0.0103
Echinococcus granulosus Peptidase C19 ubiquitin carboxyl terminal hydrolase 2 0.0022 0.0027 0.0045
Onchocerca volvulus 0.0033 0.0101 0.0157
Onchocerca volvulus 0.002 0.0011 0.0017
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0022 0.0027 0.0103
Mycobacterium tuberculosis Probable lipase LipD 0.0034 0.0112 0.0765
Trichomonas vaginalis conserved hypothetical protein 0.0022 0.0027 0.0103
Loa Loa (eye worm) heterotrimeric G protein alpha subunit 0.0036 0.0127 0.0127
Echinococcus granulosus sodium coupled monocarboxylate transporter 1 0.0033 0.0104 0.0178
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0022 0.0027 0.0103
Schistosoma mansoni serine/threonine protein kinase 0.0022 0.0025 0.0036
Echinococcus multilocularis potassium voltage gated channel subfamily H 0.002 0.0011 0.0016
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0022 0.0027 0.0103
Leishmania major ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative 0.0022 0.0027 0.0115
Brugia malayi N-terminal motif family protein 0.0032 0.0099 0.0099
Plasmodium falciparum ubiquitin specific protease, putative 0.0022 0.0027 0.0092
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.0034 0.0112 0.0765
Echinococcus multilocularis cGMP dependent protein kinase 1 0.0022 0.0025 0.0036
Leishmania major ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative 0.0022 0.0027 0.0115
Leishmania major prolyl-tRNA synthetase, putative,bifunctional aminoacyl-tRNA synthetase, putative 0.0035 0.0117 0.0788
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 4 0.0022 0.0027 0.0045
Mycobacterium ulcerans citrate (pro-3S)-lyase subunit beta 0.0024 0.0041 0.017
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0022 0.0027 0.0027
Loa Loa (eye worm) hypothetical protein 0.003 0.0082 0.0082
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0022 0.0027 0.0103
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0022 0.0027 0.0103
Toxoplasma gondii transporter, solute:sodium symporter (SSS) family protein 0.0033 0.0104 0.0501
Trichomonas vaginalis GTP-binding protein (O) alpha subunit, gnao, putative 0.0036 0.0127 0.0671
Loa Loa (eye worm) hypothetical protein 0.0022 0.0027 0.0027
Trypanosoma cruzi ubiquitin hydrolase, putative 0.0022 0.0027 0.0115
Loa Loa (eye worm) ubiquitin carboxyl-terminal hydrolase 0.0022 0.0027 0.0027
Plasmodium vivax CDK-related protein kinase 6, putative 0.0423 0.2874 1
Echinococcus granulosus Pleckstrin G protein interacting region 0.0045 0.0192 0.0327
Echinococcus multilocularis citrate lyase subunit beta protein 0.0024 0.0041 0.006
Onchocerca volvulus 0.0033 0.0104 0.0162
Schistosoma mansoni ras GTP exchange factor 0.0032 0.0099 0.0146
Echinococcus multilocularis GPCR, family 2 0.0452 0.3075 0.451
Mycobacterium tuberculosis Conserved protein 0.0034 0.0112 0.0765
Schistosoma mansoni cyclic nucleotide-gated ion channel 0.002 0.0011 0.0016
Echinococcus granulosus intermediate filament protein 0.0033 0.0101 0.0172
Trichomonas vaginalis conserved hypothetical protein 0.0022 0.0027 0.0103
Trichomonas vaginalis ras GTP exchange factor, son of sevenless, putative 0.0032 0.0099 0.0514
Echinococcus granulosus cGMP dependent protein kinase 1 0.0022 0.0025 0.0042
Leishmania major protein kinase, putative 0.0022 0.0025 0.01
Plasmodium falciparum ataxin-2 like protein, putative 0.0076 0.0409 0.1423
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0022 0.0027 0.0103
Echinococcus multilocularis cAMP dependent protein kinase regulatory 0.002 0.0011 0.0016
Mycobacterium tuberculosis Probable glutamine-transport ATP-binding protein ABC transporter GlnQ 0.002 0.0011 0.0051
Echinococcus granulosus cAMP dependent protein kinase type I beta 0.002 0.0011 0.0019
Mycobacterium ulcerans lipase LipD 0.0034 0.0112 0.057
Brugia malayi bifunctional aminoacyl-tRNA synthetase 0.003 0.0082 0.0082
Brugia malayi RasGEF domain containing protein 0.0032 0.0099 0.0099
Echinococcus granulosus u4:u6.u5 tri snrnp associated protein 2 0.0022 0.0027 0.0045
Schistosoma mansoni ap endonuclease 0.0023 0.0031 0.0045
Loa Loa (eye worm) hypothetical protein 0.0033 0.0101 0.0101
Echinococcus multilocularis geminin 0.0169 0.1068 0.1567
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.0023 0.0031 0.0045
Echinococcus granulosus solute carrier family 2 facilitated glucose 0.01 0.0577 0.0984
Echinococcus multilocularis lysyl tRNA synthetase 0.0022 0.0028 0.0041
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0022 0.0027 0.0115
Schistosoma mansoni GTP-binding protein (q) alpha-11 subunit gna11 0.0036 0.0127 0.0187
Trichomonas vaginalis Harbinger-1_Harbinger/PIFA2 transposable element protein 0.0022 0.0027 0.0103
Schistosoma mansoni lysyl-tRNA synthetase 0.0022 0.0028 0.0041
Trypanosoma brucei ubiquitin carboxyl-terminal hydrolase, putative 0.0022 0.0027 0.0115
Brugia malayi follicle stimulating hormone receptor 0.0231 0.151 0.151
Brugia malayi Hypothetical UPF0028 protein ZK370.4 in chromosome III, putative 0.002 0.0011 0.0011
Loa Loa (eye worm) hypothetical protein 0.0036 0.0127 0.0127
Entamoeba histolytica Ras guanine nucleotide exchange factor, putative 0.0032 0.0099 0.2444
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0022 0.0027 0.0103
Loa Loa (eye worm) CAMK/CAMK2 protein kinase 0.0031 0.0086 0.0086
Brugia malayi guanine nucleotide-binding protein alpha-7 subunit, putative 0.0036 0.0127 0.0127
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0079 0.0428 0.0628
Schistosoma mansoni smad1 5 8 and 0.0049 0.0217 0.0319
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0022 0.0027 0.0103
Trichomonas vaginalis ap endonuclease, putative 0.0023 0.0031 0.0128
Trypanosoma cruzi Peptidase C19, ubiquitin carboxyl-terminal hydrolase, putative 0.0022 0.0027 0.0115
Mycobacterium tuberculosis Probable hydrolase 0.0034 0.0112 0.0765
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0022 0.0027 0.0103
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0022 0.0027 0.0103
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0022 0.0027 0.0103
Trypanosoma brucei glucose transporter, putative 0.0031 0.0089 0.058
Trichomonas vaginalis GTP-binding protein (q) alpha-11 subunit, gna11, putative 0.0036 0.0127 0.0671
Trichomonas vaginalis ubiquitin specific protease, putative 0.0022 0.0027 0.0103
Plasmodium falciparum ubiquitin carboxyl-terminal hydrolase 2, putative 0.0022 0.0027 0.0092
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 4 0.0022 0.0027 0.0045
Schistosoma mansoni ubiquitin-specific peptidase 2 (C19 family) 0.0022 0.0027 0.0039
Plasmodium falciparum calcium-dependent protein kinase 1 0.0031 0.0087 0.0301
Trypanosoma cruzi hypothetical protein 0.0032 0.0099 0.0656
Giardia lamblia Hypothetical protein 0.0022 0.0027 0.2179
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0022 0.0027 0.0103
Echinococcus multilocularis son of sevenless 1 0.0032 0.0099 0.0146
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0022 0.0027 0.0103
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.002 0.0011 0.0016
Leishmania major ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative 0.0022 0.0027 0.0115
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0022 0.0027 0.0103
Plasmodium falciparum ubiquitin carboxyl-terminal hydrolase, putative 0.0022 0.0027 0.0092
Leishmania major lysyl-tRNA synthetase, putative 0.0022 0.0028 0.0124
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0022 0.0027 0.0103
Leishmania major glucose transporter, lmgt3 0.0031 0.0089 0.058
Mycobacterium ulcerans esterase/lipase LipP 0.0034 0.0112 0.057
Echinococcus granulosus geminin 0.0169 0.1068 0.1821
Schistosoma mansoni voltage-gated potassium channel 0.002 0.0011 0.0016
Brugia malayi guanine nucleotide-binding protein G-o protein alpha subunit 0.0036 0.0127 0.0127
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0022 0.0027 0.0103
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0022 0.0027 0.0103
Schistosoma mansoni ubiquitin carboxyl-terminal hydrolase of the cysteine proteinase fold 0.0022 0.0027 0.0039
Loa Loa (eye worm) transcription factor SMAD2 0.0717 0.496 0.496
Echinococcus granulosus lysyl tRNA synthetase 0.0022 0.0028 0.0047
Leishmania major hypothetical protein, conserved 0.0076 0.0409 0.2952
Plasmodium falciparum cGMP-dependent protein kinase 0.0022 0.0025 0.0086
Echinococcus granulosus cyclic nucleotide gated cation channel 0.002 0.0011 0.0019
Trichomonas vaginalis conserved hypothetical protein 0.01 0.0577 0.3208
Schistosoma mansoni GTP-binding protein (I) alpha-2 subunit gnai2 0.0036 0.0127 0.0187
Brugia malayi MH1 domain containing protein 0.0027 0.0062 0.0062
Echinococcus multilocularis mothers against decapentaplegic 2 0.0022 0.0025 0.0036
Loa Loa (eye worm) pigment dispersing factor receptor c 0.1428 1 1
Plasmodium vivax calcium-dependent protein kinase 1, putative 0.0031 0.0087 0.0301
Schistosoma mansoni camp-dependent rap1 guanine-nucleotide exchange factor 0.0031 0.0088 0.013
Giardia lamblia Ubiquitin carboxyl-terminal hydrolase 4 0.0022 0.0027 0.2179
Loa Loa (eye worm) calcium/calmodulin-dependent protein kinase ID 0.0031 0.0086 0.0086
Echinococcus granulosus son of sevenless 1 0.0032 0.0099 0.017
Plasmodium falciparum ubiquitin carboxyl-terminal hydrolase 13, putative 0.0022 0.0027 0.0092
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0022 0.0027 0.0027
Trypanosoma brucei ubiquitin carboxyl-terminal hydrolase, putative 0.0022 0.0027 0.0115
Onchocerca volvulus Rap guanine nucleotide exchange factor 1 homolog 0.0032 0.0099 0.0155
Trypanosoma cruzi hypothetical protein 0.0032 0.0099 0.0656
Schistosoma mansoni ubiquitin-specific peptidase 7 (C19 family) 0.0022 0.0027 0.0039
Brugia malayi Sugar transporter family protein 0.01 0.0577 0.0577
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0022 0.0027 0.0103
Mycobacterium tuberculosis Probable conserved transmembrane protein 0.002 0.0011 0.0051
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0845 0.5866 0.5866
Echinococcus granulosus Protein son of sevenless 0.0032 0.0099 0.017
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0022 0.0027 0.0115
Schistosoma mansoni ubiquitin-specific peptidase 44 (C19 family) 0.0022 0.0027 0.0039
Schistosoma mansoni tar DNA-binding protein 0.0384 0.2597 0.3822
Trypanosoma cruzi hypothetical protein, conserved 0.021 0.1359 1
Entamoeba histolytica Ras guanine nucleotide exchange factor, putative 0.0032 0.0099 0.2444
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0022 0.0027 0.0103
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0022 0.0027 0.0103
Schistosoma mansoni serine/threonine protein kinase 0.0031 0.0086 0.0127
Schistosoma mansoni hypothetical protein 0.0034 0.0112 0.0164
Schistosoma mansoni ubiquitin-specific peptidase 14 (C19 family) 0.0022 0.0027 0.0039
Echinococcus granulosus solute carrier family 2 facilitated glucose 0.01 0.0577 0.0984
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0022 0.0027 0.0103
Echinococcus granulosus cGMP dependent protein kinase 1 0.0022 0.0025 0.0042
Loa Loa (eye worm) ubiquitin carboxyl-terminal hydrolase 46 0.0022 0.0027 0.0027
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0079 0.0428 0.0628
Trypanosoma cruzi ubiquitin hydrolase, putative 0.0022 0.0027 0.0115
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 5 0.0022 0.0027 0.0039
Loa Loa (eye worm) hypothetical protein 0.0022 0.0028 0.0028
Echinococcus granulosus guanine nucleotide binding protein G protein 0.0036 0.0127 0.0217
Trypanosoma cruzi PAB1-binding protein , putative 0.0076 0.0409 0.2952
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0022 0.0027 0.0027
Schistosoma mansoni trimeric G-protein alpha o subunit 0.0036 0.0127 0.0187
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0022 0.0027 0.0115
Trypanosoma cruzi isocitrate dehydrogenase, putative 0.0079 0.0428 0.3094
Plasmodium vivax ubiquitin specific protease, putative 0.0022 0.0027 0.0092
Plasmodium falciparum protein kinase 7 0.0282 0.1869 0.6505
Schistosoma mansoni z-protein (S1r protein) 0.0045 0.0192 0.0282
Echinococcus granulosus cyclic nucleotide gated cation channel 0.002 0.0011 0.0019
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0022 0.0027 0.0103
Schistosoma mansoni voltage-gated potassium channel 0.002 0.0011 0.0016
Plasmodium falciparum ataxin-2 like protein, putative 0.0076 0.0409 0.1423
Mycobacterium ulcerans exodeoxyribonuclease III protein XthA 0.0023 0.0031 0.0112
Plasmodium falciparum hexose transporter 0.01 0.0577 0.201
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.0023 0.0031 0.0053
Trichomonas vaginalis penicillin-binding protein, putative 0.0034 0.0112 0.0585
Trypanosoma brucei glucose transporter, putative 0.0031 0.0089 0.058
Leishmania major ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative 0.0022 0.0027 0.0115
Echinococcus granulosus hyperpolarization activated cyclic 0.002 0.0011 0.0019
Onchocerca volvulus Rap guanine nucleotide exchange factor 1 homolog 0.0923 0.6417 1
Trypanosoma brucei THT1 - hexose transporter, putative 0.0031 0.0089 0.058
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0022 0.0027 0.0103
Mycobacterium ulcerans lysyl-tRNA synthetase 0.0022 0.0028 0.0094
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0022 0.0027 0.0103
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0022 0.0027 0.0103
Trichomonas vaginalis guanine nucleotide exchange factor, putative 0.0032 0.0099 0.0514
Leishmania major ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative 0.0022 0.0027 0.0115
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0022 0.0027 0.0103
Schistosoma mansoni cyclic-nucleotide-gated cation channel 0.002 0.0011 0.0016
Trypanosoma cruzi hypothetical protein, conserved 0.021 0.1359 1
Echinococcus granulosus rap guanine nucleotide exchange factor 1 0.0032 0.0099 0.017
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0022 0.0027 0.0103
Trichomonas vaginalis conserved hypothetical protein 0.0022 0.0027 0.0103
Echinococcus multilocularis Pleckstrin G protein, interacting region 0.0045 0.0192 0.0281
Echinococcus granulosus beta LACTamase domain containing family member 0.0034 0.0112 0.0191
Echinococcus granulosus mothers against decapentaplegic 6 0.0022 0.0025 0.0042
Schistosoma mansoni Smad4 0.0022 0.0025 0.0036
Trypanosoma brucei glucose transporter, putative 0.0031 0.0089 0.058
Loa Loa (eye worm) hypothetical protein 0.0034 0.0112 0.0112
Echinococcus multilocularis Peptidase C19, ubiquitin carboxyl terminal hydrolase 2 0.0022 0.0027 0.0039
Brugia malayi Guanine nucleotide-binding protein alpha-3 subunit, putative 0.0036 0.0127 0.0127
Trichomonas vaginalis glucose transporter, putative 0.0031 0.0089 0.0456
Plasmodium vivax ubiquitin carboxyl-terminal hydrolase 13, putative 0.0022 0.0027 0.0092
Trichomonas vaginalis ubiquitin specific protease, putative 0.0022 0.0027 0.0103
Trichomonas vaginalis conserved hypothetical protein 0.0022 0.0027 0.0103
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0022 0.0027 0.0103
Onchocerca volvulus 0.0022 0.0027 0.0041
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 5 0.0022 0.0027 0.0045
Loa Loa (eye worm) hypothetical protein 0.0076 0.0409 0.0409
Brugia malayi beta-lactamase 0.0034 0.0112 0.0112
Loa Loa (eye worm) follicle stimulating hormone receptor 0.0231 0.151 0.151
Plasmodium vivax hexose transporter 0.01 0.0577 0.201
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 0.0022 0.0027 0.0039
Schistosoma mansoni glucose transport protein 0.01 0.0577 0.085
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0022 0.0027 0.0103
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0022 0.0027 0.0027
Leishmania major ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative 0.0022 0.0027 0.0115
Echinococcus granulosus guanine nucleotide binding protein subunit 0.0036 0.0127 0.0217
Trypanosoma cruzi hexose transporter, putative 0.0031 0.0089 0.058
Mycobacterium tuberculosis Conserved protein 0.0024 0.0041 0.0264
Trichomonas vaginalis Harbinger-1_Harbinger/PIFA2 transposable element protein 0.0022 0.0027 0.0103
Schistosoma mansoni neuropathy target esterase/swiss cheese-related protein 0.002 0.0011 0.0016
Schistosoma mansoni peptidase 0.0024 0.004 0.0059
Toxoplasma gondii hypothetical protein 0.0045 0.0192 0.0973
Echinococcus granulosus high affinity choline transporter 1 0.0033 0.0104 0.0178
Trichomonas vaginalis Citrate lyase beta chain, putative 0.0024 0.0041 0.0186
Loa Loa (eye worm) hypothetical protein 0.1428 1 1
Schistosoma mansoni dishevelled 0.0045 0.0192 0.0282
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0022 0.0027 0.0027
Onchocerca volvulus 0.0032 0.0099 0.0155
Echinococcus multilocularis solute carrier family 2, facilitated glucose 0.01 0.0577 0.0847
Trichomonas vaginalis D-aminoacylase, putative 0.0034 0.0112 0.0585
Echinococcus granulosus segment polarity protein dishevelled 0.0045 0.0192 0.0327
Trypanosoma brucei ubiquitin carboxyl-terminal hydrolase, putative 0.0022 0.0027 0.0115
Echinococcus granulosus potassium voltage gated channel subfamily H 0.002 0.0011 0.0019
Echinococcus multilocularis Protein son of sevenless 0.0032 0.0099 0.0146
Plasmodium vivax CAMP-dependent protein kinase regulatory subunit, putative 0.002 0.0011 0.0038
Schistosoma mansoni hypothetical protein 0.0976 0.6795 1
Toxoplasma gondii cell-cycle-associated protein kinase MAPK, putative 0.0161 0.1013 0.5394
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0022 0.0027 0.0103
Onchocerca volvulus Segment polarity protein dishevelled homolog 0.0045 0.0192 0.0299
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0022 0.0027 0.0103
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0022 0.0027 0.0103
Loa Loa (eye worm) RNA binding protein 0.0384 0.2597 0.2597
Giardia lamblia Ubiquitin carboxyl-terminal hydrolase 4 0.0022 0.0027 0.2179
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0845 0.5866 0.8634
Echinococcus multilocularis regulator of G protein signaling 7 0.0045 0.0192 0.0281
Giardia lamblia DUB-1 0.0022 0.0027 0.2179
Echinococcus multilocularis smad 0.0049 0.0217 0.0318
Brugia malayi hypothetical protein 0.0157 0.0982 0.0982
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0022 0.0027 0.0103
Trichomonas vaginalis sugar transporter, putative 0.0031 0.0089 0.0456
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 7 0.0022 0.0027 0.0039
Trichomonas vaginalis conserved hypothetical protein 0.0022 0.0027 0.0103
Schistosoma mansoni ubiquitin-specific peptidase 45 (C19 family) 0.0022 0.0027 0.0039
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0845 0.5866 0.5866
Schistosoma mansoni amine GPCR 0.0545 0.374 0.5505
Loa Loa (eye worm) MH2 domain-containing protein 0.0049 0.0217 0.0217
Mycobacterium ulcerans citrate (pro-3S)-lyase subunit beta 0.0024 0.0041 0.017
Brugia malayi MH1 domain containing protein 0.0027 0.0062 0.0062
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0022 0.0027 0.0103
Echinococcus multilocularis mothers against decapentaplegic 5 0.0049 0.0217 0.0318
Entamoeba histolytica protein kinase, putative 0.0031 0.0086 0.2008
Plasmodium vivax ubiquitin carboxyl-terminal hydrolase 2, putative 0.0022 0.0027 0.0092
Schistosoma mansoni protein kinase 0.0031 0.0086 0.0127
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 24 0.0022 0.0027 0.0045
Echinococcus multilocularis General substrate transporter 0.0086 0.0478 0.0701
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0022 0.0027 0.0103
Trichomonas vaginalis conserved hypothetical protein 0.0022 0.0027 0.0103
Mycobacterium tuberculosis Conserved hypothetical protein 0.002 0.0011 0.0051
Toxoplasma gondii hypothetical protein 0.0022 0.0027 0.0083
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 20 0.0022 0.0027 0.0039
Trichomonas vaginalis conserved hypothetical protein 0.0022 0.0027 0.0103
Echinococcus multilocularis sodium coupled monocarboxylate transporter 1 0.0033 0.0104 0.0153
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0022 0.0027 0.0103
Toxoplasma gondii ubiquitin carboxyl-terminal hydrolase 0.0022 0.0027 0.0083
Plasmodium vivax rap guanine nucleotide exchange factor, putative 0.002 0.0011 0.0038
Loa Loa (eye worm) hypothetical protein 0.0036 0.0127 0.0127
Loa Loa (eye worm) ubiquitin carboxyl-terminal hydrolase 0.0022 0.0027 0.0027
Loa Loa (eye worm) hypothetical protein 0.0034 0.0112 0.0112
Toxoplasma gondii ubiquitin carboxyl-terminal hydrolase 0.0022 0.0027 0.0083
Trypanosoma brucei PAB1-binding protein , putative 0.0076 0.0409 0.2952
Toxoplasma gondii ubiquitin-specific protease USP4 0.0022 0.0027 0.0083
Toxoplasma gondii isocitrate dehydrogenase 0.0079 0.0428 0.2244
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0022 0.0027 0.0103
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0452 0.3075 0.5242
Trypanosoma brucei glucose transporter, putative 0.0031 0.0089 0.058
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0022 0.0027 0.0103
Giardia lamblia Prolyl-tRNA synthetase 0.003 0.0082 1
Trypanosoma cruzi cysteine peptidase, Clan CA, family C19, putative 0.0022 0.0027 0.0115
Echinococcus multilocularis guanine nucleotide binding protein (G protein) 0.0036 0.0127 0.0187
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0022 0.0027 0.0103
Echinococcus multilocularis cAMP dependent protein kinase type I beta 0.002 0.0011 0.0016
Schistosoma mansoni similar to Protein C20orf152 homolog 0.002 0.0011 0.0016
Schistosoma mansoni lamin 0.0033 0.0101 0.0148
Echinococcus granulosus lamin 0.0033 0.0101 0.0172
Leishmania major ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative 0.0022 0.0027 0.0115
Loa Loa (eye worm) guanine nucleotide-binding protein alpha-12 subunit 0.0036 0.0127 0.0127
Brugia malayi Calcitonin receptor-like protein seb-1 0.1428 1 1
Echinococcus multilocularis isocitrate dehydrogenase 0.0079 0.0428 0.0628
Brugia malayi GTP-binding regulatory protein alpha chain - starfish, putative 0.0036 0.0127 0.0127
Trypanosoma brucei calcium/calmodulin-dependent protein kinase, putative 0.0031 0.0086 0.056
Echinococcus multilocularis arachidonate 5 lipoxygenase 0.0051 0.0234 0.0344
Loa Loa (eye worm) hypothetical protein 0.0034 0.0112 0.0112
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 0.0022 0.0027 0.0045
Echinococcus multilocularis expressed protein 0.0036 0.0127 0.0187
Brugia malayi GH02984p 0.0033 0.0104 0.0104
Loa Loa (eye worm) hypothetical protein 0.0045 0.0192 0.0192
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0022 0.0027 0.0103
Trichomonas vaginalis esterase, putative 0.0034 0.0112 0.0585
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 23 0.0022 0.0027 0.0045
Loa Loa (eye worm) hypothetical protein 0.0452 0.3075 0.3075
Schistosoma mansoni glutamyl-tRNA synthetase cytoplasmic (glutamate--tRNA ligase) (glurs) 0.003 0.0082 0.0121
Schistosoma mansoni regulator of G protein signaling 0.0045 0.0192 0.0282
Schistosoma mansoni ubiquitin-specific peptidase 8 (C19 family) 0.0022 0.0027 0.0039
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0079 0.0428 0.0628
Trypanosoma brucei ubiquitin carboxyl-terminal hydrolase, putative 0.0022 0.0027 0.0115
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0022 0.0027 0.0103
Echinococcus granulosus regulator of G protein signaling 7 0.0045 0.0192 0.0327
Loa Loa (eye worm) hypothetical protein 0.0027 0.0062 0.0062
Echinococcus granulosus calcium dependent protein kinase 0.0029 0.0073 0.0125
Trypanosoma cruzi prolyl-tRNA synthetase, putative 0.0035 0.0117 0.0788
Loa Loa (eye worm) RasGEF domain-containing protein 0.0032 0.0099 0.0099
Schistosoma mansoni hypothetical protein 0.0452 0.3075 0.4526
Loa Loa (eye worm) hypothetical protein 0.0022 0.0027 0.0027
Echinococcus granulosus expressed protein 0.0036 0.0127 0.0217
Mycobacterium tuberculosis Conserved protein 0.0034 0.0112 0.0765
Entamoeba histolytica Ras guanine nucleotide exchange factor, putative 0.0032 0.0099 0.2444
Loa Loa (eye worm) hypothetical protein 0.0032 0.0099 0.0099
Plasmodium falciparum mitogen-activated protein kinase 2 0.0161 0.1013 0.3527
Schistosoma mansoni ubiquitin-specific peptidase 46 (C19 family) 0.0022 0.0027 0.0039
Entamoeba histolytica hypothetical protein 0.0064 0.0325 1
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 1 0.0031 0.0086 0.0147
Loa Loa (eye worm) cyclic-nucleotide gated cation channel 0.002 0.0011 0.0011
Echinococcus granulosus cAMP dependent protein kinase type II regulatory 0.002 0.0011 0.0019
Schistosoma mansoni NADP-specific isocitrate dehydrogenase 0.0079 0.0428 0.063
Trypanosoma cruzi ubiquitin hydrolase, putative 0.0022 0.0027 0.0115
Mycobacterium tuberculosis Probable lipase LipE 0.0034 0.0112 0.0765
Mycobacterium tuberculosis Probable conserved transmembrane transport protein 0.002 0.0011 0.0051
Echinococcus multilocularis isocitrate dehydrogenase 2 (NADP+) 0.0079 0.0428 0.0628
Schistosoma mansoni tar DNA-binding protein 0.0384 0.2597 0.3822
Trichomonas vaginalis conserved hypothetical protein 0.0022 0.0027 0.0103
Schistosoma mansoni GTP-binding protein (I) alpha-1subunit gnai1 0.0036 0.0127 0.0187
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0031 0.0086 0.0127
Schistosoma mansoni neuropathy target esterase/swiss cheese-related protein 0.002 0.0011 0.0016
Echinococcus multilocularis cGMP dependent protein kinase 1 0.0022 0.0025 0.0036
Echinococcus granulosus guanine nucleotide binding protein subunit 0.0036 0.0127 0.0217
Trypanosoma cruzi ubiquitin hydrolase, putative 0.0022 0.0027 0.0115
Schistosoma mansoni hypothetical protein 0.0452 0.3075 0.4526
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0022 0.0027 0.0103
Loa Loa (eye worm) AGC/PKG protein kinase 0.0022 0.0025 0.0025
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 16 0.0022 0.0027 0.0045
Schistosoma mansoni calpain-7 (C02 family) 0.0022 0.0027 0.0039
Echinococcus multilocularis sodium:glucose cotransporter 2 0.0033 0.0104 0.0153
Schistosoma mansoni cyclic-nucleotide-gated cation channel 0.002 0.0011 0.0016
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 7 0.0022 0.0027 0.0045
Trypanosoma brucei Peptidase C19, ubiquitin carboxyl-terminal hydrolase, putative 0.0022 0.0027 0.0115
Loa Loa (eye worm) hypothetical protein 0.0045 0.0192 0.0192
Plasmodium vivax mitogen-activated protein kinase 2, putative 0.0161 0.1013 0.3527
Plasmodium falciparum ubiquitin specific protease, putative 0.0022 0.0027 0.0092
Loa Loa (eye worm) hypothetical protein 0.0032 0.0097 0.0097
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0022 0.0027 0.0103
Trypanosoma cruzi lysyl-tRNA synthetase, putative 0.0022 0.0028 0.0124
Schistosoma mansoni GTP-binding protein alpha subunit 0.0036 0.0127 0.0187
Schistosoma mansoni cyclic-nucleotide-gated cation channel 0.002 0.0011 0.0016
Leishmania major ubiqitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative 0.0022 0.0027 0.0115
Echinococcus granulosus smad 0.0049 0.0217 0.0369
Loa Loa (eye worm) hypothetical protein 0.0022 0.0027 0.0027
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0022 0.0027 0.0103
Toxoplasma gondii ubiquitin carboxyl-terminal hydrolase 0.0022 0.0027 0.0083
Schistosoma mansoni glucose transport protein 0.01 0.0577 0.085
Loa Loa (eye worm) intermediate filament protein 0.0033 0.0101 0.0101
Loa Loa (eye worm) TAR-binding protein 0.0384 0.2597 0.2597
Schistosoma mansoni smad1 5 8 and 0.0049 0.0217 0.0319
Echinococcus multilocularis TGF beta signal transducer SmadC 0.0049 0.0217 0.0318
Trichomonas vaginalis D-aminoacylase, putative 0.0034 0.0112 0.0585
Schistosoma mansoni GTP-binding protein (q) alpha-11 subunit gna11 0.0036 0.0127 0.0187
Plasmodium vivax ubiquitin carboxyl-terminal hydrolase family 2, putative 0.0022 0.0027 0.0092
Loa Loa (eye worm) hypothetical protein 0.0976 0.6795 0.6795
Trypanosoma brucei glucose transporter 1E 0.0031 0.0089 0.058
Mycobacterium leprae Conserved hypothetical protein 0.002 0.0011 0.0661
Trypanosoma cruzi hypothetical protein, conserved 0.0034 0.0112 0.075
Toxoplasma gondii ubiquitin specific protease 39 isoform 2, putative 0.0022 0.0027 0.0083
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0022 0.0027 0.0103
Toxoplasma gondii protein kinase G AGC kinase family member PKG 0.0022 0.0025 0.0073
Echinococcus granulosus cyclic nucleotide gated cation channel alpha 3 0.002 0.0011 0.0019
Echinococcus multilocularis u4:u6.u5 tri snrnp associated protein 2 0.0022 0.0027 0.0039
Loa Loa (eye worm) sugar transporter 0.01 0.0577 0.0577
Leishmania major protein kinase, putative 0.0031 0.0086 0.056
Mycobacterium leprae conserved hypothetical protein 0.0034 0.0112 1
Trypanosoma brucei glucose transporter 2A 0.0031 0.0089 0.058
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0022 0.0027 0.0103
Schistosoma mansoni voltage-gated potassium channel 0.002 0.0011 0.0016
Schistosoma mansoni GTP-binding protein (I) alpha-2 subunit gnai2 0.0036 0.0127 0.0187
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0031 0.0086 0.0127
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0845 0.5866 1
Mycobacterium tuberculosis Probable isocitrate dehydrogenase [NADP] Icd1 (oxalosuccinate decarboxylase) (IDH) (NADP+-specific ICDH) (IDP) 0.0079 0.0428 0.2999
Toxoplasma gondii ubiquitin carboxyl-terminal hydrolase 0.0022 0.0027 0.0083
Toxoplasma gondii ubiquitin carboxyl-terminal hydrolase 0.0022 0.0027 0.0083
Schistosoma mansoni lipoxygenase 0.0051 0.0234 0.0345
Mycobacterium tuberculosis Probable citrate (pro-3S)-lyase (beta subunit) CitE (citrase) (citratase) (citritase) (citridesmolase) (citrase aldolase) 0.0024 0.0041 0.0264
Entamoeba histolytica Ras guanine nucleotide exchange factor, putative 0.0032 0.0099 0.2444
Schistosoma mansoni inositol transporter 0.0033 0.0104 0.0153
Mycobacterium tuberculosis Possible penicillin-binding protein 0.0218 0.1418 1
Leishmania major apurinic/apyrimidinic endonuclease-redox protein 0.0023 0.0031 0.0147
Loa Loa (eye worm) ubiquitin carboxyl-terminal hydrolase 0.0022 0.0027 0.0027
Mycobacterium tuberculosis Conserved protein 0.002 0.0011 0.0051
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0034 0.0112 0.0165
Trypanosoma brucei cysteine peptidase, Clan CA, family C19, putative 0.0022 0.0027 0.0115
Entamoeba histolytica Ras guanine nucleotide exchange factor, putative 0.0032 0.0099 0.2444
Schistosoma mansoni ubiquitin-specific peptidase 9X (C19 family) 0.0022 0.0027 0.0039
Onchocerca volvulus 0.0157 0.0982 0.1531
Loa Loa (eye worm) cAMP-dependent protein kinase regulatory subunit 0.002 0.0011 0.0011
Loa Loa (eye worm) hypothetical protein 0.0022 0.0027 0.0027
Brugia malayi Guanine nucleotide-binding protein alpha-6 subunit, putative 0.0036 0.0127 0.0127
Schistosoma mansoni TGF-beta signal transducer Smad2 0.0049 0.0217 0.0319
Schistosoma mansoni hypothetical protein 0.01 0.0577 0.085
Mycobacterium ulcerans citrate lyase beta subunit, CitE_2 0.0024 0.0041 0.017
Echinococcus multilocularis solute carrier family 2 facilitated glucose 0.01 0.0577 0.0847
Loa Loa (eye worm) hypothetical protein 0.0034 0.0112 0.0112
Wolbachia endosymbiont of Brugia malayi exonuclease III 0.0023 0.0031 0.5
Echinococcus granulosus gtp binding protein I alpha 1subunit 0.0036 0.0127 0.0217
Leishmania major glucose transporter, lmgt2 0.0031 0.0089 0.058
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0022 0.0027 0.0103
Schistosoma mansoni camp-dependent protein kinase regulatory chain 0.002 0.0011 0.0016
Loa Loa (eye worm) hypothetical protein 0.0022 0.0027 0.0027
Brugia malayi ubiquitin specific protease 14 0.0022 0.0027 0.0027
Schistosoma mansoni GTP-binding protein alpha subunit 0.0036 0.0127 0.0187
Echinococcus multilocularis ubiquitin specific peptidase 42 (C19 family) 0.0022 0.0027 0.0039
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0022 0.0027 0.0103
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0022 0.0027 0.0027
Loa Loa (eye worm) hypothetical protein 0.0036 0.0127 0.0127
Onchocerca volvulus 0.0034 0.0112 0.0175
Echinococcus granulosus solute carrier family 2 facilitated glucose 0.01 0.0577 0.0984
Toxoplasma gondii calcium-dependent protein kinase CDPK2A 0.0031 0.0087 0.0406
Trypanosoma cruzi hexose transporter, putative 0.0031 0.0089 0.058
Echinococcus granulosus General substrate transporter 0.0086 0.0478 0.0815
Loa Loa (eye worm) hypothetical protein 0.0022 0.0025 0.0025
Mycobacterium tuberculosis Conserved protein 0.0034 0.0112 0.0765
Entamoeba histolytica Ras guanine nucleotide exchange factor, putative 0.0032 0.0099 0.2444
Schistosoma mansoni tar DNA-binding protein 0.0384 0.2597 0.3822
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0022 0.0027 0.0103
Leishmania major hypothetical protein, conserved 0.021 0.1359 1
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0022 0.0027 0.0103
Plasmodium vivax proline--tRNA ligase, putative 0.0035 0.0117 0.0408
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0022 0.0027 0.0103
Schistosoma mansoni glucose transport protein 0.01 0.0577 0.085
Echinococcus multilocularis ubiquitin specific peptidase (c family) ubiquitin terminal hydrolase 0.0022 0.0027 0.0039
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 47 0.0022 0.0027 0.0045
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0022 0.0027 0.0103
Trichomonas vaginalis ap endonuclease, putative 0.0023 0.0031 0.0128
Trypanosoma brucei glucose transporter, putative 0.0031 0.0089 0.058
Toxoplasma gondii prolyl-tRNA synthetase (ProRS) 0.0035 0.0117 0.0571
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0022 0.0027 0.0115
Trypanosoma brucei THT1 - hexose transporter, putative 0.0031 0.0089 0.058
Echinococcus granulosus potassium voltage gated channel subfamily H 0.002 0.0011 0.0019
Schistosoma mansoni inositol transporter 0.0033 0.0104 0.0153
Echinococcus granulosus rap guanine nucleotide exchange factor 6 0.0032 0.0099 0.017
Echinococcus granulosus sodium:glucose cotransporter 2 0.0033 0.0104 0.0178
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0022 0.0027 0.0027
Toxoplasma gondii LsmAD domain-containing protein 0.0076 0.0409 0.214
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0022 0.0027 0.0027
Trypanosoma cruzi ubiquitin hydrolase, putative 0.0022 0.0027 0.0115
Loa Loa (eye worm) hypothetical protein 0.0024 0.0042 0.0042
Loa Loa (eye worm) ubiquitin specific peptidase 39 0.0022 0.0027 0.0027
Brugia malayi hypothetical protein 0.0064 0.0325 0.0325
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0022 0.0027 0.0103
Schistosoma mansoni cyclic-nucleotide-gated cation channel 0.002 0.0011 0.0016
Mycobacterium tuberculosis Probable conserved lipoprotein 0.0034 0.0112 0.0765
Loa Loa (eye worm) glutaminase 0.027 0.1783 0.1783
Loa Loa (eye worm) hypothetical protein 0.0022 0.0027 0.0027
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 22 0.0022 0.0027 0.0045
Echinococcus multilocularis Ataxin 2, N terminal,domain containing protein 0.0034 0.0112 0.0164
Leishmania major ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative 0.0022 0.0027 0.0115
Trichomonas vaginalis ras GTP exchange factor, putative 0.0032 0.0099 0.0514
Trichomonas vaginalis conserved hypothetical protein 0.0022 0.0027 0.0103
Schistosoma mansoni GTP-binding protein (I) alpha-1subunit gnai1 0.0036 0.0127 0.0187
Brugia malayi latrophilin 2 splice variant baaae 0.0976 0.6795 0.6795
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0022 0.0027 0.0027
Echinococcus multilocularis Smad4 0.0049 0.0217 0.0318
Brugia malayi TAR-binding protein 0.0384 0.2597 0.2597
Brugia malayi Guanine nucleotide-binding protein alpha-3 subunit, putative 0.0036 0.0127 0.0127
Plasmodium vivax AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0023 0.0031 0.0108
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0034 0.0112 0.0112
Plasmodium vivax ubiquitin carboxyl-terminal hydrolase, putative 0.0022 0.0027 0.0092
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0022 0.0027 0.0103
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 12 0.0022 0.0027 0.0045
Entamoeba histolytica hypothetical protein 0.0022 0.0028 0.004
Schistosoma mansoni ras GTP exchange factor son of sevenless 0.0032 0.0099 0.0146
Schistosoma mansoni glutaminase 0.027 0.1783 0.2624
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0022 0.0027 0.0115
Trypanosoma brucei ubiquitin carboxyl-terminal hydrolase, putative 0.0022 0.0027 0.0115
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0034 0.0112 0.0165
Leishmania major protein kinase, putative 0.0022 0.0025 0.01
Echinococcus multilocularis cyclic nucleotide gated cation channel alpha 3 0.002 0.0011 0.0016
Brugia malayi lysyl-tRNA synthetase 0.0022 0.0028 0.0028
Plasmodium vivax hypothetical protein, conserved 0.0034 0.0112 0.039
Trypanosoma cruzi ubiquitin hydrolase, putative 0.0022 0.0027 0.0115
Toxoplasma gondii ubiquitin carboxyl-terminal hydrolase 0.0022 0.0027 0.0083
Brugia malayi RasGEF domain containing protein 0.0032 0.0099 0.0099
Trypanosoma brucei ubiquitin carboxyl-terminal hydrolase, putative 0.0022 0.0027 0.0115
Leishmania major ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative 0.0022 0.0027 0.0115
Schistosoma mansoni GTP-binding protein (I) alpha subunit gnai 0.0036 0.0127 0.0187
Loa Loa (eye worm) hypothetical protein 0.0022 0.0027 0.0027
Toxoplasma gondii protein kinase, putative 0.0282 0.1869 1
Schistosoma mansoni ubiquitin-specific peptidase 16 (C19 family) 0.0022 0.0027 0.0039
Schistosoma mansoni smad 0.0049 0.0217 0.0319
Schistosoma mansoni ubiquitin-specific peptidase 10 (C19 family) 0.0022 0.0027 0.0039
Brugia malayi isocitrate dehydrogenase 0.0079 0.0428 0.0428
Brugia malayi N-terminal motif family protein 0.0032 0.0099 0.0099
Leishmania major ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative 0.0022 0.0027 0.0115
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0022 0.0027 0.0103
Echinococcus multilocularis patatin phospholipase domain containing protein 0.002 0.0011 0.0016
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0452 0.3075 0.3075
Brugia malayi G-protein alpha subunit 0.0036 0.0127 0.0127
Schistosoma mansoni protein kinase 0.0031 0.0086 0.0127
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0022 0.0027 0.0027
Trichomonas vaginalis conserved hypothetical protein 0.0022 0.0027 0.0103
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0022 0.0027 0.0103
Echinococcus granulosus GPCR family 2 0.0452 0.3075 0.5242
Onchocerca volvulus 0.0045 0.0192 0.0299
Toxoplasma gondii ubiquitin carboxyl-terminal hydrolase 0.0022 0.0027 0.0083
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0022 0.0027 0.0103
Trichomonas vaginalis lysyl-tRNA synthetase, putative 0.0022 0.0028 0.011
Echinococcus multilocularis segment polarity protein dishevelled 0.0045 0.0192 0.0281
Echinococcus multilocularis expressed conserved protein 0.0022 0.0025 0.0036
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0031 0.0086 0.0127
Brugia malayi Domain found in Dishevelled, Egl-10, and Pleckstrin family protein 0.0045 0.0192 0.0192
Trypanosoma brucei hypothetical protein, conserved 0.0034 0.0112 0.075
Echinococcus multilocularis lamin dm0 0.0033 0.0101 0.0148
Trypanosoma cruzi hypothetical protein, conserved 0.0034 0.0112 0.075
Trypanosoma brucei ubiquitin carboxyl-terminal hydrolase, putative 0.0022 0.0027 0.0115
Trichomonas vaginalis conserved hypothetical protein 0.0022 0.0027 0.0103
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0022 0.0027 0.0103
Trypanosoma cruzi cysteine peptidase, Clan CA, family C19, putative 0.0022 0.0027 0.0115
Trypanosoma cruzi ubiquitin hydrolase, putative 0.0022 0.0027 0.0115
Schistosoma mansoni lamin 0.0033 0.0101 0.0148
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0022 0.0027 0.0027
Loa Loa (eye worm) Smad1 0.0049 0.0217 0.0217
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 20 0.0022 0.0027 0.0045
Echinococcus granulosus mothers against decapentaplegic 2 0.0022 0.0025 0.0042
Trichomonas vaginalis G protein (olf) alpha subunit, gnal, putative 0.0036 0.0127 0.0671
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0022 0.0027 0.0103
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0022 0.0027 0.0103
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0022 0.0027 0.0103
Brugia malayi hypothetical protein 0.0076 0.0409 0.0409
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0022 0.0027 0.0103
Leishmania major glucose transporter, lmgt1 0.0031 0.0089 0.058
Loa Loa (eye worm) isocitrate dehydrogenase 0.0079 0.0428 0.0428
Echinococcus multilocularis expressed protein 0.0022 0.0027 0.0039
Echinococcus granulosus tar DNA binding protein 0.0384 0.2597 0.4427
Trichomonas vaginalis GTP-binding protein (z) alpha subunit, gnaz, putative 0.0036 0.0127 0.0671
Brugia malayi mothers against decapentaplegic homolog 3 0.0022 0.0025 0.0025
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0022 0.0027 0.0103
Echinococcus granulosus patatin phospholipase domain containing protein 0.002 0.0011 0.0019
Trichomonas vaginalis Harbinger-1_Harbinger/PIFA2 transposable element protein 0.0022 0.0027 0.0103
Loa Loa (eye worm) hypothetical protein 0.0033 0.0104 0.0104
Trypanosoma brucei isocitrate dehydrogenase, putative 0.0079 0.0428 0.3094
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0022 0.0027 0.0103
Loa Loa (eye worm) hypothetical protein 0.0036 0.0127 0.0127
Loa Loa (eye worm) beta-lactamase 0.0034 0.0112 0.0112
Echinococcus granulosus ubiquitin specific peptidase 30 (C19 family) 0.0022 0.0027 0.0045
Plasmodium vivax ubiquitin carboxyl-terminal hydrolase, putative 0.0022 0.0027 0.0092
Onchocerca volvulus 0.0034 0.0112 0.0175
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 12 0.0022 0.0027 0.0039
Echinococcus multilocularis hyperpolarization activated cyclic 0.002 0.0011 0.0016
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0064 0.0325 0.0476
Trypanosoma brucei glucose transporter, putative 0.0031 0.0089 0.058
Entamoeba histolytica hypothetical protein 0.0064 0.0325 1
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0022 0.0027 0.0027
Schistosoma mansoni ubiquitin-specific peptidase 30 (C19 family) 0.0022 0.0027 0.0039
Chlamydia trachomatis lysine--tRNA ligase 0.0022 0.0028 1
Echinococcus granulosus voltage gated potassium channel 0.002 0.0011 0.0019
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0022 0.0027 0.0103
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0022 0.0027 0.0103
Trypanosoma cruzi ubiquitin hydrolase, putative 0.0022 0.0027 0.0115
Schistosoma mansoni intermediate filament proteins 0.0033 0.0101 0.0148
Brugia malayi RasGEF domain containing protein 0.0032 0.0099 0.0099
Loa Loa (eye worm) guanine nucleotide-binding protein alpha-6 subunit 0.0036 0.0127 0.0127
Entamoeba histolytica Ras guanine nucleotide exchange factor, putative 0.0032 0.0099 0.2444
Schistosoma mansoni GTP-binding protein alpha subunit gna 0.0036 0.0127 0.0187
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0022 0.0027 0.0103
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0022 0.0027 0.0103
Brugia malayi beta-lactamase family protein 0.0034 0.0112 0.0112
Echinococcus granulosus Smad4 0.0049 0.0217 0.0369
Trypanosoma cruzi prolyl-tRNA synthetase, putative 0.0035 0.0117 0.0788
Echinococcus granulosus sodium:myo inositol cotransporter 0.0033 0.0104 0.0178
Trichomonas vaginalis GTP-binding protein alpha subunit, gna, putative 0.0036 0.0127 0.0671
Brugia malayi Latrophilin receptor protein 2 0.0452 0.3075 0.3075
Plasmodium falciparum AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0023 0.0031 0.0108
Echinococcus multilocularis solute carrier family 5 0.0033 0.0104 0.0153
Entamoeba histolytica Ras guanine nucleotide exchange factor, putative 0.0032 0.0099 0.2444
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0022 0.0027 0.0103
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0022 0.0027 0.0115
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0022 0.0027 0.0103
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.0034 0.0112 0.057
Plasmodium falciparum protein kinase 6 0.0423 0.2874 1
Schistosoma mansoni lysyl-tRNA synthetase 0.0022 0.0028 0.0041
Brugia malayi Bifunctional aminoacyl-tRNA synthetase 0.003 0.0082 0.0082
Schistosoma mansoni hypothetical protein 0.0022 0.0027 0.0039
Echinococcus granulosus sodium:glucose cotransporter 0.0033 0.0104 0.0178
Echinococcus multilocularis potassium voltage gated channel subfamily H 0.002 0.0011 0.0016
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0845 0.5866 0.8634
Entamoeba histolytica hypothetical protein 0.0064 0.0325 1
Brugia malayi Cam kinase protein 1 0.0031 0.0086 0.0086
Schistosoma mansoni calpain-7 (C02 family) 0.0022 0.0027 0.0039
Trichomonas vaginalis conserved hypothetical protein 0.002 0.0011 0.0016
Echinococcus multilocularis calcium dependent protein kinase 0.0029 0.0073 0.0107
Trichomonas vaginalis CAMK family protein kinase 0.0031 0.0086 0.0441
Trypanosoma cruzi ubiquitin hydrolase, putative 0.0022 0.0027 0.0115
Brugia malayi MH2 domain containing protein 0.0022 0.0025 0.0025
Loa Loa (eye worm) hypothetical protein 0.0034 0.0112 0.0112
Brugia malayi Isocitrate dehydrogenase 0.0079 0.0428 0.0428
Loa Loa (eye worm) ubiquitin carboxyl-terminal hydrolase 0.0022 0.0027 0.0027
Trypanosoma cruzi ubiquitin hydrolase, putative 0.0022 0.0027 0.0115
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0022 0.0027 0.0103
Loa Loa (eye worm) glutaminase 2 0.027 0.1783 0.1783
Echinococcus granulosus guanine nucleotide binding protein G protein 0.0036 0.0127 0.0217
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.002 0.0011 0.0016
Trichomonas vaginalis ubiquitin specific protease, putative 0.0022 0.0027 0.0103
Brugia malayi Voltage-gated potassium channel, HERG (KCNH2)-related. C. elegans unc-103 ortholog 0.002 0.0011 0.0011
Mycobacterium leprae Probable prolyl tRNA synthetase ProS 0.003 0.0082 0.7222
Echinococcus granulosus ras GTP exchange factor 0.0032 0.0099 0.017
Echinococcus multilocularis beta LACTamase domain containing family member 0.0034 0.0112 0.0164
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0022 0.0027 0.0103
Loa Loa (eye worm) hypothetical protein 0.0036 0.0127 0.0127
Onchocerca volvulus 0.002 0.0011 0.0017
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0022 0.0027 0.0103
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0022 0.0027 0.0103
Brugia malayi Cyclic-nucleotide gated cation channel, C. elegans tax-4 ortholog 0.002 0.0011 0.0011
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0022 0.0027 0.0103
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.002 0.0011 0.0016
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0022 0.0027 0.0103
Brugia malayi cAMP-dependent protein kinase regulatory chain, putative 0.002 0.0011 0.0011
Trypanosoma brucei glucose transporter, putative 0.0031 0.0089 0.058
Leishmania major ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative 0.0022 0.0027 0.0115
Echinococcus multilocularis regulator of G protein signaling 7 0.0045 0.0192 0.0281
Toxoplasma gondii ubiquitin carboxyl-terminal hydrolase 0.0022 0.0027 0.0083
Brugia malayi MH1 domain containing protein 0.0049 0.0217 0.0217
Echinococcus granulosus citrate lyase subunit beta protein 0.0024 0.0041 0.007
Brugia malayi guanine nucleotide-binding protein alpha-3 subunit, putative 0.0036 0.0127 0.0127
Loa Loa (eye worm) hypothetical protein 0.0022 0.0027 0.0027
Trichomonas vaginalis Harbinger-1_Harbinger/PIFA2 transposable element protein 0.0022 0.0027 0.0103
Schistosoma mansoni ras GTP exchange factor son of sevenless 0.0032 0.0099 0.0146
Brugia malayi hypothetical protein 0.0022 0.0027 0.0027
Schistosoma mansoni camp-dependent protein kinase type I-beta regulatory subunit 0.002 0.0011 0.0016
Onchocerca volvulus 0.0036 0.0127 0.0198
Echinococcus multilocularis potassium:sodium hyperpolarization activated 0.002 0.0011 0.0016
Plasmodium vivax calcium-dependent protein kinase 3, putative 0.0031 0.0087 0.0301
Toxoplasma gondii ubiquitin carboxyl-terminal hydrolase family 2 protein 0.0022 0.0027 0.0083
Echinococcus granulosus arachidonate 5 lipoxygenase 0.0051 0.0234 0.04
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0022 0.0027 0.0103
Schistosoma mansoni sodium/solute symporter 0.0033 0.0104 0.0153
Trypanosoma brucei isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0079 0.0428 0.3094
Onchocerca volvulus 0.0022 0.0027 0.0041
Leishmania major ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative 0.0022 0.0027 0.0115
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0022 0.0027 0.0103
Entamoeba histolytica Ras guanine nucleotide exchange factor, putative 0.0032 0.0099 0.2444
Schistosoma mansoni hyperpolarization activated cyclic nucleotide-gated potassium channel 0.002 0.0011 0.0016
Trichomonas vaginalis glutaminase, putative 0.027 0.1783 1
Schistosoma mansoni hyperpolarization activated cyclic nucleotide-gated potassium channel 0.002 0.0011 0.0016
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 8 0.0022 0.0027 0.0039
Plasmodium vivax calcium-dependent protein kinase 4, putative 0.0031 0.0087 0.0301
Trypanosoma brucei ubiquitin carboxyl-terminal hydrolase, putative 0.0022 0.0027 0.0115
Trichomonas vaginalis conserved hypothetical protein 0.0022 0.0027 0.0103
Entamoeba histolytica exodeoxyribonuclease III, putative 0.0023 0.0031 0.0147
Echinococcus multilocularis glutamyl tRNA synthetase cytoplasmic 0.003 0.0082 0.012
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 36 0.0022 0.0027 0.0039
Echinococcus multilocularis cAMP dependent protein kinase type II regulatory 0.002 0.0011 0.0016
Loa Loa (eye worm) hypothetical protein 0.0022 0.0027 0.0027
Schistosoma mansoni Smad4 0.0022 0.0025 0.0036
Plasmodium vivax calcium-dependent protein kinase, putative 0.0031 0.0087 0.0301
Brugia malayi Cyclic-nucleotide gated cation channel 0.002 0.0011 0.0011
Schistosoma mansoni ubiquitin-specific peptidase 24 (C19 family) 0.0022 0.0027 0.0039
Schistosoma mansoni tar DNA-binding protein 0.0384 0.2597 0.3822
Echinococcus multilocularis hyperpolarization activated cyclic 0.002 0.0011 0.0016
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0022 0.0027 0.0103
Loa Loa (eye worm) hypothetical protein 0.002 0.0011 0.0011
Leishmania major hypothetical protein, conserved 0.0034 0.0112 0.075
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0022 0.0027 0.0103
Brugia malayi beta-lactamase family protein 0.0034 0.0112 0.0112
Echinococcus multilocularis guanine nucleotide binding protein subunit 0.0036 0.0127 0.0187
Loa Loa (eye worm) MH2 domain-containing protein 0.0022 0.0025 0.0025
Trichomonas vaginalis GTP-binding protein alpha subunit, gna, putative 0.0036 0.0127 0.0671
Loa Loa (eye worm) ubiquitin carboxyl-terminal hydrolase 0.0022 0.0027 0.0027
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.002 0.0011 0.0016
Plasmodium falciparum isocitrate dehydrogenase [NADP], mitochondrial 0.0079 0.0428 0.149
Loa Loa (eye worm) voltage and ligand gated potassium channel 0.002 0.0011 0.0011
Loa Loa (eye worm) hypothetical protein 0.0157 0.0982 0.0982
Trichomonas vaginalis GTP-binding protein alpha subunit, gna, putative 0.0036 0.0127 0.0671
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0022 0.0027 0.0103
Schistosoma mansoni tar DNA-binding protein 0.0384 0.2597 0.3822
Schistosoma mansoni ras GTP exchange factor son of sevenless 0.0032 0.0099 0.0146
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0022 0.0027 0.0103
Schistosoma mansoni voltage-gated potassium channel 0.002 0.0011 0.0016
Brugia malayi MH2 domain containing protein 0.0049 0.0217 0.0217
Loa Loa (eye worm) hypothetical protein 0.0045 0.0192 0.0192
Mycobacterium tuberculosis Probable esterase LipL 0.0034 0.0112 0.0765
Brugia malayi Calcium/calmodulin-dependent protein kinase type II alpha chain 0.0031 0.0086 0.0086
Trichomonas vaginalis conserved hypothetical protein 0.0022 0.0027 0.0103
Treponema pallidum exodeoxyribonuclease (exoA) 0.0023 0.0031 1
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0022 0.0027 0.0103
Brugia malayi intermediate filament protein 0.0033 0.0101 0.0101
Schistosoma mansoni glutamyl-tRNA synthetase cytoplasmic (glutamate--tRNA ligase) (glurs) 0.003 0.0082 0.0121
Plasmodium vivax U4/U6.U5 tri-snRNP-associated protein 2, putative 0.0022 0.0027 0.0092
Echinococcus multilocularis solute carrier family 2 facilitated glucose 0.01 0.0577 0.0847
Brugia malayi N-terminal motif family protein 0.0923 0.6417 0.6417
Trypanosoma brucei lysyl-tRNA synthetase, putative 0.0022 0.0028 0.0124
Echinococcus multilocularis sodium:myo inositol cotransporter 0.0033 0.0104 0.0153
Echinococcus granulosus TGF beta signal transducer SmadC 0.0049 0.0217 0.0369
Echinococcus granulosus mothers against decapentaplegic 5 0.0049 0.0217 0.0369
Echinococcus granulosus solute carrier family 5 0.0033 0.0104 0.0178
Echinococcus multilocularis lamin 0.0033 0.0101 0.0148
Trichomonas vaginalis cAMP-dependent protein kinase regulatory subunit, putative 0.002 0.0011 0.0016
Schistosoma mansoni hypothetical protein 0.0452 0.3075 0.4526
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0022 0.0027 0.0103
Mycobacterium ulcerans beta-lactamase 0.0034 0.0112 0.057
Echinococcus multilocularis Ubiquitin carboxyl terminal hydrolase 48 0.0022 0.0027 0.0039
Schistosoma mansoni transcription factor LCR-F1 0.0064 0.0325 0.0478
Schistosoma mansoni smad 0.0022 0.0025 0.0036
Trypanosoma cruzi PAB1-binding protein , putative 0.0076 0.0409 0.2952
Trypanosoma cruzi ubiquitin hydrolase, putative 0.0022 0.0027 0.0115
Toxoplasma gondii ABC1 family protein 0.0034 0.0112 0.0544
Loa Loa (eye worm) hypothetical protein 0.0033 0.0104 0.0104
Toxoplasma gondii facilitative glucose transporter GT1 0.01 0.0577 0.3048
Mycobacterium leprae Probable lipase LipE 0.0034 0.0112 1
Echinococcus multilocularis high affinity choline transporter 1 0.0033 0.0104 0.0153
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0452 0.3075 0.451
Loa Loa (eye worm) latrophilin receptor protein 2 0.0452 0.3075 0.3075
Plasmodium vivax ataxin-2 like protein, putative 0.0076 0.0409 0.1423
Plasmodium vivax isocitrate dehydrogenase [NADP], mitochondrial, putative 0.0079 0.0428 0.149
Loa Loa (eye worm) G protein alpha subunit 3 0.0036 0.0127 0.0127
Echinococcus granulosus regulator of G protein signaling 7 0.0045 0.0192 0.0327
Giardia lamblia Lysyl-tRNA synthetase 0.0022 0.0028 0.2345
Schistosoma mansoni hypothetical protein 0.0169 0.1068 0.1572
Entamoeba histolytica hypothetical protein 0.0032 0.0099 0.2444
Schistosoma mansoni hypothetical protein 0.0064 0.0325 0.0478
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 7 0.0022 0.0027 0.0045
Onchocerca volvulus 0.0022 0.0027 0.0041
Trichomonas vaginalis sugar transporter, putative 0.0031 0.0089 0.0456
Schistosoma mansoni hypothetical protein 0.002 0.0011 0.0016
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 0.0031 0.0086 0.0147
Brugia malayi hypothetical protein 0.0045 0.0192 0.0192
Echinococcus granulosus segment polarity protein dishevelled 0.0045 0.0192 0.0327
Echinococcus multilocularis segment polarity protein dishevelled 0.0045 0.0192 0.0281
Echinococcus multilocularis mothers against decapentaplegic 6 0.0022 0.0025 0.0036
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0022 0.0027 0.0103
Entamoeba histolytica G protein alpha subunit, putative 0.0036 0.0127 0.3378
Brugia malayi Smad1 0.0049 0.0217 0.0217
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0022 0.0027 0.0103
Schistosoma mansoni camp-dependent protein kinase type I-beta regulatory subunit 0.002 0.0011 0.0016
Brugia malayi Guanine nucleotide-binding protein alpha-12 subunit, putative 0.0036 0.0127 0.0127
Trypanosoma cruzi ubiquitin hydrolase, putative 0.0022 0.0027 0.0115
Brugia malayi Intermediate filament tail domain containing protein 0.0033 0.0101 0.0101
Brugia malayi Sodium:solute symporter family protein 0.0033 0.0104 0.0104
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0022 0.0027 0.0103
Echinococcus multilocularis rap guanine nucleotide exchange factor 6 0.0032 0.0099 0.0146
Brugia malayi hypothetical protein 0.0036 0.0127 0.0127
Schistosoma mansoni hypothetical protein 0.0452 0.3075 0.4526
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0022 0.0027 0.0027
Trypanosoma cruzi cysteine peptidase, Clan CA, family C19, putative 0.0022 0.0027 0.0115
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 4 0.0022 0.0027 0.0039
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 47 0.0022 0.0027 0.0039
Trichomonas vaginalis GTP-binding protein alpha subunit, gna, putative 0.0036 0.0127 0.0671
Toxoplasma gondii calcium-dependent protein kinase CDPK2B 0.0031 0.0087 0.0406
Trichomonas vaginalis conserved hypothetical protein 0.0022 0.0027 0.0103
Echinococcus multilocularis rap guanine nucleotide exchange factor 1 0.0032 0.0099 0.0146
Giardia lamblia Ubiquitin carboxyl-terminal hydrolase 14 0.0022 0.0027 0.2179
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0022 0.0027 0.0103
Mycobacterium ulcerans lysyl-tRNA synthetase 0.0022 0.0028 0.0094
Loa Loa (eye worm) hypothetical protein 0.0022 0.0027 0.0027
Schistosoma mansoni smad1 5 8 and 0.0049 0.0217 0.0319
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.0034 0.0112 0.0765
Trichomonas vaginalis conserved hypothetical protein 0.0022 0.0027 0.0103
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0022 0.0027 0.0027
Trichomonas vaginalis conserved hypothetical protein 0.0031 0.0089 0.0456
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 14 0.0022 0.0027 0.0039
Trichomonas vaginalis D-aminoacylase, putative 0.0034 0.0112 0.0585
Trypanosoma brucei THT1 - hexose transporter, putative 0.0031 0.0089 0.058
Echinococcus multilocularis solute carrier family 2 facilitated glucose 0.01 0.0577 0.0847
Echinococcus granulosus NADP dependent isocitrate dehydrogenase 0.0079 0.0428 0.073
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0022 0.0027 0.0103
Schistosoma mansoni high-affinity choline transporter 0.0033 0.0104 0.0153
Echinococcus granulosus Ataxin 2 N terminaldomain containing protein 0.0034 0.0112 0.019
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0022 0.0027 0.0103
Loa Loa (eye worm) hypothetical protein 0.0022 0.0027 0.0027
Schistosoma mansoni GTP-binding protein (I) alpha-2 subunit gnai2 0.0036 0.0127 0.0187
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0022 0.0027 0.0103
Echinococcus multilocularis ras GTP exchange factor 0.0032 0.0099 0.0146
Trypanosoma cruzi ubiquitin hydrolase, putative 0.0022 0.0027 0.0115
Entamoeba histolytica prolyl-tRNA synthetase, putative 0.003 0.0082 0.1861
Leishmania major glucose transporter/membrane transporter D2, putative 0.0031 0.0089 0.058
Plasmodium falciparum calcium-dependent protein kinase 2 0.0031 0.0087 0.0301
Mycobacterium leprae Possible lysyl-tRNA synthetase 2 LysX 0.0022 0.0028 0.22
Echinococcus granulosus cyclic nucleotide gated cation channel 0.002 0.0011 0.0019
Schistosoma mansoni ubiquitin-specific peptidase 4 (C19 family) 0.0022 0.0027 0.0039
Brugia malayi guanine nucleotide-binding protein G(o), alpha subunit, putative 0.0036 0.0127 0.0127
Brugia malayi MH2 domain containing protein 0.0717 0.496 0.496
Trypanosoma brucei Peptidase C19, ubiquitin carboxyl-terminal hydrolase, putative 0.0022 0.0027 0.0115
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0022 0.0027 0.0103
Mycobacterium ulcerans hypothetical protein 0.0024 0.0041 0.017
Echinococcus multilocularis cyclic nucleotide gated cation channel 0.002 0.0011 0.0016
Echinococcus granulosus Ubiquitin carboxyl terminal hydrolase 48 0.0022 0.0027 0.0045
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0064 0.0325 0.0554
Leishmania major ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative 0.0022 0.0027 0.0115
Echinococcus granulosus cAMP dependent protein kinase regulatory 0.002 0.0011 0.0019
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0845 0.5866 0.8603
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 4 0.0022 0.0027 0.0045
Toxoplasma gondii UBA/TS-N domain-containing protein 0.0022 0.0027 0.0083
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0022 0.0027 0.0103
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0022 0.0027 0.0103
Onchocerca volvulus 0.0036 0.0127 0.0198
Leishmania major ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative 0.0022 0.0027 0.0115
Entamoeba histolytica Ras guanine nucleotide exchange factor, putative 0.0032 0.0099 0.2444
Trypanosoma cruzi 2,4-dihydroxyhept-2-ene-1,7-dioic acid aldolase, putative 0.0024 0.0041 0.0224
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0022 0.0027 0.0103
Trichomonas vaginalis conserved hypothetical protein 0.0022 0.0027 0.0103
Trichomonas vaginalis glucose transporter, putative 0.0031 0.0089 0.0456
Toxoplasma gondii isocitrate dehydrogenase 0.0079 0.0428 0.2244
Loa Loa (eye worm) hypothetical protein 0.0031 0.0086 0.0086
Entamoeba histolytica hypothetical protein 0.0064 0.0325 1
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0022 0.0027 0.0103
Trichomonas vaginalis sugar transporter, putative 0.0031 0.0089 0.0456
Echinococcus multilocularis cyclic nucleotide gated cation channel 0.002 0.0011 0.0016
Loa Loa (eye worm) DIX domain-containing protein 0.0045 0.0192 0.0192
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.0023 0.0031 0.0147
Echinococcus multilocularis voltage gated potassium channel 0.002 0.0011 0.0016
Onchocerca volvulus 0.0034 0.0112 0.0175
Brugia malayi Voltage-gated potassium channel, EAG (KCNH1)-related. C. elegans egl-2 ortholog 0.002 0.0011 0.0011
Loa Loa (eye worm) hypothetical protein 0.0034 0.0112 0.0112
Trypanosoma brucei hypothetical protein, conserved 0.021 0.1359 1
Trichomonas vaginalis cAMP-dependent protein kinase type I-beta regulatory subunit, putative 0.002 0.0011 0.0016
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0022 0.0027 0.0103
Schistosoma mansoni ubiquitin-specific peptidase 9X (C19 family) 0.0022 0.0027 0.0039
Brugia malayi exodeoxyribonuclease III family protein 0.0023 0.0031 0.0031
Trichomonas vaginalis conserved hypothetical protein 0.0022 0.0027 0.0103
Trypanosoma brucei ubiquitin carboxyl-terminal hydrolase, putative 0.0022 0.0027 0.0115
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 36 0.0022 0.0027 0.0045
Entamoeba histolytica protein kinase, putative 0.0031 0.0086 0.2008
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0022 0.0027 0.0103
Schistosoma mansoni fyve finger-containing phosphoinositide kinase fyv1 0.0045 0.0192 0.0282
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.0023 0.0031 0.0031
Mycobacterium ulcerans hypothetical protein 0.0034 0.0112 0.057
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0022 0.0027 0.0103
Trypanosoma brucei bifunctional aminoacyl-tRNA synthetase, putative 0.0035 0.0117 0.0788
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 0.0031 0.0086 0.0147
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0022 0.0027 0.0103
Schistosoma mansoni camp-dependent protein kinase type II-alpha regulatory subunit 0.002 0.0011 0.0016
Echinococcus multilocularis musashi 0.0033 0.0101 0.0148
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0022 0.0027 0.0115
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0022 0.0027 0.0103
Loa Loa (eye worm) ubiquitin carboxyl-terminal hydrolase 0.0022 0.0027 0.0027
Echinococcus granulosus 5'partial|Ubiquitin carboxyl terminal hydrolase 48 0.0022 0.0027 0.0045
Echinococcus multilocularis tar DNA binding protein 0.0384 0.2597 0.3809
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0022 0.0027 0.0103
Schistosoma mansoni guanine-nucleotide-exchange-factor 0.0032 0.0099 0.0146
Trypanosoma cruzi ubiquitin hydrolase, putative 0.0022 0.0027 0.0115
Echinococcus multilocularis cyclic nucleotide gated cation channel 0.002 0.0011 0.0016
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0034 0.0112 0.0112
Trypanosoma cruzi guanine nucleotide releasing protein, putative 0.0032 0.0099 0.0656
Schistosoma mansoni ubiquitin-specific peptidase 5 (C19 family) 0.0022 0.0027 0.0039
Schistosoma mansoni camp-dependent protein kinase type II regulatory subunit 0.002 0.0011 0.0016
Plasmodium falciparum U4/U6.U5 tri-snRNP-associated protein 2, putative 0.0022 0.0027 0.0092
Plasmodium falciparum ubiquitin carboxyl-terminal hydrolase, putative 0.0022 0.0027 0.0092
Brugia malayi DIX domain containing protein 0.0045 0.0192 0.0192
Echinococcus granulosus ubiquitin specific protease 41 0.0022 0.0027 0.0045
Loa Loa (eye worm) ubiquitin carboxyl-terminal hydrolase 0.0022 0.0027 0.0027
Loa Loa (eye worm) hypothetical protein 0.0923 0.6417 0.6417
Mycobacterium ulcerans glutaminase 0.027 0.1783 1
Trypanosoma cruzi hexose transporter 0.0031 0.0089 0.058
Plasmodium falciparum calcium-dependent protein kinase 4 0.0031 0.0087 0.0301
Mycobacterium ulcerans hypothetical protein 0.0024 0.0041 0.017
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 8 0.0022 0.0027 0.0045
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0022 0.0027 0.0103
Echinococcus multilocularis gtp binding protein (I) alpha 1subunit 0.0036 0.0127 0.0187
Loa Loa (eye worm) cyclic-nucleotide gated cation channel 0.002 0.0011 0.0011
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.0033 0.0101 0.0101
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 16 0.0022 0.0027 0.0039
Loa Loa (eye worm) MH2 domain-containing protein 0.0717 0.496 0.496
Loa Loa (eye worm) nuclear factor I 0.0027 0.0062 0.0062
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0022 0.0027 0.0103
Schistosoma mansoni hyperpolarization activated cyclic nucleotide-gated potassium channel 0.002 0.0011 0.0016
Trypanosoma brucei ubiquitin carboxyl-terminal hydrolase, putative 0.0022 0.0027 0.0115
Loa Loa (eye worm) RasGEF domain-containing protein 0.0032 0.0099 0.0099
Leishmania major ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative 0.0022 0.0027 0.0115
Brugia malayi glutaminase DH11.1 0.027 0.1783 0.1783
Trypanosoma cruzi 2,4-dihydroxyhept-2-ene-1,7-dioic acid aldolase, putative 0.0024 0.0041 0.0224
Trichomonas vaginalis prolyl-tRNA synthetase, putative 0.003 0.0082 0.0416
Toxoplasma gondii exonuclease III APE 0.0023 0.0031 0.0107
Trypanosoma brucei ubiquitin carboxyl-terminal hydrolase, putative 0.0022 0.0027 0.0115
Giardia lamblia Endonuclease/Exonuclease/phosphatase 0.0023 0.0031 0.2794
Trypanosoma cruzi Peptidase C19, ubiquitin carboxyl-terminal hydrolase, putative 0.0022 0.0027 0.0115
Onchocerca volvulus Mothers against decapentaplegic homolog 0.0022 0.0025 0.0039
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 22 0.0022 0.0027 0.0039
Loa Loa (eye worm) RasGEF domain-containing protein 0.0032 0.0099 0.0099
Brugia malayi Domain found in Dishevelled, Egl-10, and Pleckstrin family protein 0.0045 0.0192 0.0192
Loa Loa (eye worm) G protein signaling regulator EGL-10 0.0045 0.0192 0.0192
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0022 0.0027 0.0027
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0022 0.0027 0.0103
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0022 0.0027 0.0103
Schistosoma mansoni family C19 unassigned peptidase (C19 family) 0.0022 0.0027 0.0039
Schistosoma mansoni serine/threonine protein kinase 0.0022 0.0025 0.0036
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0022 0.0027 0.0027
Trypanosoma brucei ubiquitin carboxyl-terminal hydrolase, putative 0.0022 0.0027 0.0115
Loa Loa (eye worm) MH1 domain-containing protein 0.0022 0.0025 0.0025
Schistosoma mansoni Smad4 0.0049 0.0217 0.0319
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0022 0.0027 0.0103
Entamoeba histolytica Ras guanine nucleotide exchange factor, putative 0.0032 0.0099 0.2444
Loa Loa (eye worm) GTP-binding regulatory protein alpha chain 0.0036 0.0127 0.0127
Echinococcus granulosus glutamyl tRNA synthetase cytoplasmic 0.003 0.0082 0.014
Trichomonas vaginalis conserved hypothetical protein 0.0031 0.0089 0.0456
Giardia lamblia Ubiquitin carboxyl-terminal hydrolase 14 0.0022 0.0027 0.2179
Schistosoma mansoni dishevelled 0.0045 0.0192 0.0282
Schistosoma mansoni ubiquitin-specific peptidase 22 (C19 family) 0.0022 0.0027 0.0039
Loa Loa (eye worm) hypothetical protein 0.003 0.0082 0.0082
Schistosoma mansoni family C19 non-peptidase homologue (C19 family) 0.0022 0.0027 0.0039
Trichomonas vaginalis ras GTP exchange factor, putative 0.0032 0.0099 0.0514
Brugia malayi hypothetical protein 0.0045 0.0192 0.0192
Leishmania major prolyl-tRNA synthetase, putative,bifunctional aminoacyl-tRNA synthetase, putative 0.0035 0.0117 0.0788
Trichomonas vaginalis conserved hypothetical protein 0.0022 0.0027 0.0103
Brugia malayi MH1 domain containing protein 0.0049 0.0217 0.0217
Plasmodium vivax hypothetical protein, conserved 0.0022 0.0027 0.0092
Mycobacterium tuberculosis Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) 0.0023 0.0031 0.0191
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0022 0.0027 0.0103
Loa Loa (eye worm) hypothetical protein 0.0022 0.0027 0.0027
Schistosoma mansoni dep domain containing protein 0.0045 0.0192 0.0282
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0022 0.0027 0.0103
Schistosoma mansoni protein kinase 0.0031 0.0086 0.0127
Trichomonas vaginalis conserved hypothetical protein 0.0022 0.0027 0.0103
Plasmodium falciparum proline--tRNA ligase 0.0035 0.0117 0.0408
Leishmania major 2,4-dihydroxyhept-2-ene-1,7-dioic acid aldolase, putative 0.0024 0.0041 0.0224
Echinococcus multilocularis ubiquitin specific protease 41 0.0022 0.0027 0.0039
Trypanosoma cruzi hexose transporter, putative 0.0031 0.0089 0.058
Echinococcus granulosus lamin dm0 0.0033 0.0101 0.0172
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative 0.0023 0.0031 0.0147
Schistosoma mansoni serine/threonine protein kinase 0.0022 0.0025 0.0036
Leishmania major isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0079 0.0428 0.3094
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0452 0.3075 0.451
Echinococcus multilocularis guanine nucleotide binding protein (G protein) 0.0036 0.0127 0.0187
Brugia malayi hypothetical protein 0.0049 0.0218 0.0218
Brugia malayi RNA binding protein 0.0384 0.2597 0.2597
Entamoeba histolytica Ras guanine nucleotide exchange factor, putative 0.0032 0.0099 0.2444
Echinococcus multilocularis atpase aaa+ type core atpase aaa type core 0.0979 0.6819 1
Plasmodium falciparum ubiquitin carboxyl-terminal hydrolase 14 0.0022 0.0027 0.0092
Entamoeba histolytica Ras guanine nucleotide exchange factor, putative 0.0032 0.0099 0.2444
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0022 0.0027 0.0027
Echinococcus granulosus cGMP dependent protein kinase 0.0022 0.0025 0.0042
Echinococcus granulosus potassium:sodium hyperpolarization activated 0.002 0.0011 0.0019
Mycobacterium tuberculosis Conserved hypothetical protein 0.002 0.0011 0.0051
Schistosoma mansoni ap endonuclease 0.0023 0.0031 0.0045
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0022 0.0027 0.0115
Loa Loa (eye worm) hypothetical protein 0.0022 0.0027 0.0027
Plasmodium falciparum lysine--tRNA ligase 0.0022 0.0028 0.0096
Schistosoma mansoni ubiquitin-specific peptidase 42 (C19 family) 0.0022 0.0027 0.0039
Echinococcus granulosus hyperpolarization activated cyclic 0.002 0.0011 0.0019
Toxoplasma gondii lysine-tRNA ligase 0.0022 0.0028 0.009
Echinococcus granulosus ubiquitin specific peptidase c family 0.0022 0.0027 0.0045
Trichomonas vaginalis penicillin-binding protein, putative 0.0034 0.0112 0.0585
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 14 0.0022 0.0027 0.0045
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0031 0.0086 0.0127
Plasmodium falciparum cAMP-dependent protein kinase regulatory subunit 0.002 0.0011 0.0038
Loa Loa (eye worm) RNA recognition domain-containing protein domain-containing protein 0.0384 0.2597 0.2597
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0022 0.0027 0.0103
Loa Loa (eye worm) hypothetical protein 0.0032 0.0099 0.0099
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0452 0.3075 0.5242

Activities

Activity type Activity value Assay description Source Reference
Potency (functional) = 6.3096 um PUBCHEM_BIOASSAY: qHTS Assay for Modulators of Lamin A Splicing. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) 7.0795 uM PubChem BioAssay. qHTS Assay for Inhibitors of the Human Apurinic/apyrimidinic Endonuclease 1 (APE1). (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) 11.6891 uM PUBCHEM_BIOASSAY: Primary qHTS for delayed death inhibitors of the malarial parasite plastid, 96 hour incubation. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID488745, AID488752, AID488774, AID504848, AID504850] ChEMBL. No reference
Potency (functional) 16.3601 uM PUBCHEM_BIOASSAY: Nrf2 qHTS screen for inhibitors. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID493153, AID493163, AID504648] ChEMBL. No reference
Potency (functional) 18.3489 uM PUBCHEM_BIOASSAY: qHTS screen for small molecules that induce genotoxicity in human embryonic kidney (HEK293T) cells expressing luciferase-tagged ELG1. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID493106, AID493143] ChEMBL. No reference
Potency (functional) 21.1923 uM PubChem BioAssay. qHTS for Inhibitors of ATXN expression. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) 89.1251 uM PUBCHEM_BIOASSAY: qHTS for Inhibitors of Polymerase Iota. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID588623] ChEMBL. No reference

Phenotypes

Whole-cell/tissue/organism interactions

Species name Source Reference Is orphan
Plasmodium falciparum ChEMBL23

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

Bibliographic References

No literature references available for this target.

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