Detailed information for compound 1329382

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 319.317 | Formula: C17H13N5O2
  • H donors: 2 H acceptors: 3 LogP: 4.26 Rotable bonds: 3
    Rule of 5 violations (Lipinski): 1
  • SMILES: Oc1[nH]c2c(c1N=NC(=O)c1c(C)nc3n1cccc3)cccc2
  • InChi: 1S/C17H13N5O2/c1-10-15(22-9-5-4-8-13(22)18-10)17(24)21-20-14-11-6-2-3-7-12(11)19-16(14)23/h2-9,19,23H,1H3
  • InChiKey: HCHLRGQSYJIQHE-UHFFFAOYSA-N  


Substructure search Similarity search

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

Species Target name Source Bibliographic reference
Homo sapiens glucagon-like peptide 1 receptor Starlite/ChEMBL No references
Homo sapiens nuclear factor, erythroid 2-like 2 Starlite/ChEMBL No references
Trypanosoma cruzi cysteine peptidase, putative Starlite/ChEMBL No references
Homo sapiens lamin A/C Starlite/ChEMBL No references
Homo sapiens APEX nuclease (multifunctional DNA repair enzyme) 1 Starlite/ChEMBL No references

Predicted pathogen targets for this compound

By orthology
Species Potential target Known druggable target/s Ortholog Group
Leishmania donovani apurinic/apyrimidinic endonuclease-redox protein Get druggable targets OG5_126768 All targets in OG5_126768
Trypanosoma congolense cysteine peptidase, Clan CA, family C1, Cathepsin L-like Get druggable targets OG5_126607 All targets in OG5_126607
Schistosoma japonicum Lamin-C, putative Get druggable targets OG5_128723 All targets in OG5_128723
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase Get druggable targets OG5_126607 All targets in OG5_126607
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase Get druggable targets OG5_126607 All targets in OG5_126607
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase Get druggable targets OG5_126607 All targets in OG5_126607
Trypanosoma congolense cysteine peptidase, Clan CA, family C1, Cathepsin L-like Get druggable targets OG5_126607 All targets in OG5_126607
Trypanosoma congolense cysteine peptidase, Clan CA, family C1, Cathepsin L-like Get druggable targets OG5_126607 All targets in OG5_126607
Trypanosoma cruzi cruzipain precursor, putative Get druggable targets OG5_126607 All targets in OG5_126607
Brugia malayi Cathepsin L-like precursor Get druggable targets OG5_126607 All targets in OG5_126607
Trichomonas vaginalis ap endonuclease, putative Get druggable targets OG5_126768 All targets in OG5_126768
Leishmania infantum apurinic/apyrimidinic endonuclease-redox protein Get druggable targets OG5_126768 All targets in OG5_126768
Schistosoma mansoni intermediate filament proteins Get druggable targets OG5_128723 All targets in OG5_128723
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like Get druggable targets OG5_126607 All targets in OG5_126607
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase Get druggable targets OG5_126607 All targets in OG5_126607
Leishmania donovani cysteine peptidase A (CBA) Get druggable targets OG5_126607 All targets in OG5_126607
Plasmodium falciparum cysteine proteinase falcipain 3 Get druggable targets OG5_126607 All targets in OG5_126607
Leishmania infantum cathepsin L-like protease Get druggable targets OG5_126607 All targets in OG5_126607
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_126607 All targets in OG5_126607
Mycobacterium tuberculosis Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) Get druggable targets OG5_126768 All targets in OG5_126768
Entamoeba histolytica cysteine protease, putative Get druggable targets OG5_126607 All targets in OG5_126607
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_126607 All targets in OG5_126607
Echinococcus granulosus cytoplasmic intermediate filament protein Get druggable targets OG5_128723 All targets in OG5_128723
Leishmania major cysteine peptidase A (CPA) Get druggable targets OG5_126607 All targets in OG5_126607
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase Get druggable targets OG5_126607 All targets in OG5_126607
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase Get druggable targets OG5_126607 All targets in OG5_126607
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase Get druggable targets OG5_126607 All targets in OG5_126607
Candida albicans similar to S. cerevisiae APN2 (YBL019W) DNA repair apurinic/apyrimidinic endonuclease Get druggable targets OG5_126768 All targets in OG5_126768
Theileria parva cysteine proteinase, putative Get druggable targets OG5_126607 All targets in OG5_126607
Schistosoma japonicum expressed protein Get druggable targets OG5_128723 All targets in OG5_128723
Loa Loa (eye worm) exodeoxyribonuclease III family protein Get druggable targets OG5_126768 All targets in OG5_126768
Wolbachia endosymbiont of Brugia malayi exonuclease III Get druggable targets OG5_126768 All targets in OG5_126768
Trypanosoma congolense cysteine peptidase, Clan CA, family C1, Cathepsin L-like Get druggable targets OG5_126607 All targets in OG5_126607
Leishmania major cathepsin L-like protease Get druggable targets OG5_126607 All targets in OG5_126607
Leishmania mexicana cathepsin L-like protease, putative Get druggable targets OG5_126607 All targets in OG5_126607
Brugia malayi Cathepsin L-like precursor Get druggable targets OG5_126607 All targets in OG5_126607
Trypanosoma brucei gambiense apurinic/apyrimidinic endonuclease, putative Get druggable targets OG5_126768 All targets in OG5_126768
Trypanosoma congolense cysteine peptidase, Clan CA, family C1, Cathepsin L-like Get druggable targets OG5_126607 All targets in OG5_126607
Echinococcus granulosus cathepsin L cysteine proteinase Get druggable targets OG5_126607 All targets in OG5_126607
Trypanosoma congolense cysteine peptidase, Clan CA, family C1, Cathepsin L-like Get druggable targets OG5_126607 All targets in OG5_126607
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase Get druggable targets OG5_126607 All targets in OG5_126607
Plasmodium knowlesi knowpain-3 Get druggable targets OG5_126607 All targets in OG5_126607
Brugia malayi Cathepsin L-like precursor Get druggable targets OG5_126607 All targets in OG5_126607
Entamoeba histolytica cysteine proteinase, putative Get druggable targets OG5_126607 All targets in OG5_126607
Plasmodium knowlesi AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative Get druggable targets OG5_126768 All targets in OG5_126768
Trypanosoma congolense cysteine peptidase, Clan CA, family C1, Cathepsin L-like Get druggable targets OG5_126607 All targets in OG5_126607
Trypanosoma brucei gambiense cysteine peptidase precursor,cysteine peptidase, Clan CA, family C1, Cathepsin L-like Get druggable targets OG5_126607 All targets in OG5_126607
Echinococcus granulosus lamin Get druggable targets OG5_128723 All targets in OG5_128723
Leishmania infantum cysteine peptidase A (CPA) Get druggable targets OG5_126607 All targets in OG5_126607
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like Get druggable targets OG5_126607 All targets in OG5_126607
Trypanosoma cruzi cysteine peptidase, putative Get druggable targets OG5_126607 All targets in OG5_126607
Echinococcus multilocularis cathepsin l cysteine peptidase Get druggable targets OG5_126607 All targets in OG5_126607
Brugia malayi Papain family cysteine protease containing protein Get druggable targets OG5_126607 All targets in OG5_126607
Trypanosoma congolense cysteine peptidase, Clan CA, family C1, Cathepsin L-like Get druggable targets OG5_126607 All targets in OG5_126607
Plasmodium yoelii berghepain-2 Get druggable targets OG5_126607 All targets in OG5_126607
Onchocerca volvulus Get druggable targets OG5_126607 All targets in OG5_126607
Schistosoma japonicum ko:K07611 lamin, putative Get druggable targets OG5_128723 All targets in OG5_128723
Schistosoma japonicum ko:K10772 AP endonuclease 2, putative Get druggable targets OG5_126768 All targets in OG5_126768
Leishmania braziliensis cathepsin L-like protease Get druggable targets OG5_126607 All targets in OG5_126607
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase Get druggable targets OG5_126607 All targets in OG5_126607
Onchocerca volvulus Get druggable targets OG5_126607 All targets in OG5_126607
Leishmania braziliensis apurinic/apyrimidinic endonuclease-redox protein Get druggable targets OG5_126768 All targets in OG5_126768
Leishmania major cathepsin L-like protease Get druggable targets OG5_126607 All targets in OG5_126607
Theileria parva cysteine proteinase, putative Get druggable targets OG5_126607 All targets in OG5_126607
Trypanosoma congolense cysteine peptidase, Clan CA, family C1, Cathepsin L-like Get druggable targets OG5_126607 All targets in OG5_126607
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like Get druggable targets OG5_126607 All targets in OG5_126607
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like Get druggable targets OG5_126607 All targets in OG5_126607
Trypanosoma brucei gambiense cysteine peptidase precursor,cysteine peptidase, Clan CA, family C1, Cathepsin L-like Get druggable targets OG5_126607 All targets in OG5_126607
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase Get druggable targets OG5_126607 All targets in OG5_126607
Plasmodium falciparum cysteine proteinase falcipain 2a Get druggable targets OG5_126607 All targets in OG5_126607
Entamoeba histolytica cysteine proteinase, putative Get druggable targets OG5_126607 All targets in OG5_126607
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like Get druggable targets OG5_126607 All targets in OG5_126607
Schistosoma mansoni lamin Get druggable targets OG5_128723 All targets in OG5_128723
Leishmania major apurinic/apyrimidinic endonuclease-redox protein Get druggable targets OG5_126768 All targets in OG5_126768
Theileria parva cysteine proteinase, putative Get druggable targets OG5_126607 All targets in OG5_126607
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase Get druggable targets OG5_126607 All targets in OG5_126607
Loa Loa (eye worm) ctsf protein Get druggable targets OG5_126607 All targets in OG5_126607
Cryptosporidium hominis cryptopain precursor Get druggable targets OG5_126607 All targets in OG5_126607
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_128723 All targets in OG5_128723
Plasmodium falciparum cysteine proteinase falcipain 2b Get druggable targets OG5_126607 All targets in OG5_126607
Loa Loa (eye worm) fibroinase Get druggable targets OG5_126607 All targets in OG5_126607
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like Get druggable targets OG5_126607 All targets in OG5_126607
Schistosoma japonicum expressed protein Get druggable targets OG5_126607 All targets in OG5_126607
Leishmania mexicana Get druggable targets OG5_126607 All targets in OG5_126607
Theileria parva cysteine proteinase Get druggable targets OG5_126607 All targets in OG5_126607
Theileria parva cysteine protease, putative Get druggable targets OG5_126607 All targets in OG5_126607
Trypanosoma cruzi cysteine peptidase, clan CA, family C1, cathepsin L-like, putative Get druggable targets OG5_126607 All targets in OG5_126607
Trypanosoma brucei gambiense cysteine peptidase precursor,cysteine peptidase, Clan CA, family C1, Cathepsin L-like Get druggable targets OG5_126607 All targets in OG5_126607
Trypanosoma cruzi cysteine peptidase, putative Get druggable targets OG5_126607 All targets in OG5_126607
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase Get druggable targets OG5_126607 All targets in OG5_126607
Onchocerca volvulus Get druggable targets OG5_128723 All targets in OG5_128723
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like Get druggable targets OG5_126607 All targets in OG5_126607
Onchocerca volvulus Get druggable targets OG5_126607 All targets in OG5_126607
Mycobacterium ulcerans exodeoxyribonuclease III protein XthA Get druggable targets OG5_126768 All targets in OG5_126768
Trypanosoma congolense cysteine peptidase, Clan CA, family C1, Cathepsin L-like Get druggable targets OG5_126607 All targets in OG5_126607
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase Get druggable targets OG5_126607 All targets in OG5_126607
Neospora caninum Cathepsin L, related Get druggable targets OG5_126607 All targets in OG5_126607
Plasmodium berghei AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative Get druggable targets OG5_126768 All targets in OG5_126768
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_128723 All targets in OG5_128723
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_126607 All targets in OG5_126607
Plasmodium berghei berghepain-2 Get druggable targets OG5_126607 All targets in OG5_126607
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase Get druggable targets OG5_126607 All targets in OG5_126607
Schistosoma mansoni cathepsin F (C01 family) Get druggable targets OG5_126607 All targets in OG5_126607
Loa Loa (eye worm) intermediate filament tail domain-containing protein Get druggable targets OG5_128723 All targets in OG5_128723
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase Get druggable targets OG5_126607 All targets in OG5_126607
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase Get druggable targets OG5_126607 All targets in OG5_126607
Onchocerca volvulus Cathepsin L homolog Get druggable targets OG5_126607 All targets in OG5_126607
Trypanosoma cruzi apurinic/apyrimidinic endonuclease Get druggable targets OG5_126768 All targets in OG5_126768
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase Get druggable targets OG5_126768 All targets in OG5_126768
Trypanosoma congolense cysteine peptidase, Clan CA, family C1, Cathepsin L-like Get druggable targets OG5_126607 All targets in OG5_126607
Schistosoma japonicum ko:K10771 AP endonuclease 1, putative Get druggable targets OG5_126768 All targets in OG5_126768
Loa Loa (eye worm) intermediate filament protein Get druggable targets OG5_128723 All targets in OG5_128723
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like Get druggable targets OG5_126607 All targets in OG5_126607
Schistosoma japonicum Intermediate filament protein ifa-1, putative Get druggable targets OG5_128723 All targets in OG5_128723
Plasmodium vivax vivapain-2 Get druggable targets OG5_126607 All targets in OG5_126607
Echinococcus granulosus lamin dm0 Get druggable targets OG5_128723 All targets in OG5_128723
Schistosoma japonicum expressed protein Get druggable targets OG5_128723 All targets in OG5_128723
Treponema pallidum exodeoxyribonuclease (exoA) Get druggable targets OG5_126768 All targets in OG5_126768
Schistosoma mansoni cathepsin F (C01 family) Get druggable targets OG5_126607 All targets in OG5_126607
Plasmodium knowlesi knowpain-2 Get druggable targets OG5_126607 All targets in OG5_126607
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like Get druggable targets OG5_126607 All targets in OG5_126607
Leishmania mexicana cathepsin L-like protease, putative Get druggable targets OG5_126607 All targets in OG5_126607
Theileria parva cysteine protease, putative Get druggable targets OG5_126607 All targets in OG5_126607
Trypanosoma congolense cysteine peptidase, Clan CA, family C1, Cathepsin L-like Get druggable targets OG5_126607 All targets in OG5_126607
Echinococcus multilocularis cysteine protease Get druggable targets OG5_126607 All targets in OG5_126607
Leishmania major cathepsin L-like protease Get druggable targets OG5_126607 All targets in OG5_126607
Brugia malayi Cathepsin L-like precursor Get druggable targets OG5_126607 All targets in OG5_126607
Leishmania mexicana Get druggable targets OG5_126607 All targets in OG5_126607
Brugia malayi exodeoxyribonuclease III family protein Get druggable targets OG5_126768 All targets in OG5_126768
Loa Loa (eye worm) cysteine protease Get druggable targets OG5_126607 All targets in OG5_126607
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase Get druggable targets OG5_126607 All targets in OG5_126607
Leishmania major cathepsin L-like protease Get druggable targets OG5_126607 All targets in OG5_126607
Onchocerca volvulus Get druggable targets OG5_126607 All targets in OG5_126607
Leishmania mexicana Get druggable targets OG5_126607 All targets in OG5_126607
Schistosoma japonicum Cathepsin L-like proteinase precursor, putative Get druggable targets OG5_126607 All targets in OG5_126607
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative Get druggable targets OG5_126768 All targets in OG5_126768
Leishmania mexicana apurinic/apyrimidinic endonuclease-redox protein,AP-endonuclease Get druggable targets OG5_126768 All targets in OG5_126768
Candida albicans similar to S. cerevisiae APN2 (YBL019W) DNA repair apurinic/apyrimidinic endonuclease Get druggable targets OG5_126768 All targets in OG5_126768
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase Get druggable targets OG5_126607 All targets in OG5_126607
Schistosoma mansoni cathepsin F (C01 family) Get druggable targets OG5_126607 All targets in OG5_126607
Schistosoma mansoni lamin Get druggable targets OG5_128723 All targets in OG5_128723
Echinococcus multilocularis cytoplasmic intermediate filament protein Get druggable targets OG5_128723 All targets in OG5_128723
Plasmodium yoelii putative AP endonuclease-related Get druggable targets OG5_126768 All targets in OG5_126768
Trypanosoma congolense cysteine peptidase, Clan CA, family C1, Cathepsin L-like Get druggable targets OG5_126607 All targets in OG5_126607
Trypanosoma cruzi cysteine peptidase, putative Get druggable targets OG5_126607 All targets in OG5_126607
Schistosoma japonicum DNA-(apurinic or apyrimidinic site) lyase 2, putative Get druggable targets OG5_126768 All targets in OG5_126768
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase Get druggable targets OG5_126607 All targets in OG5_126607
Toxoplasma gondii cathepsin CPL Get druggable targets OG5_126607 All targets in OG5_126607
Leishmania major cathepsin L-like protease Get druggable targets OG5_126607 All targets in OG5_126607
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative Get druggable targets OG5_126768 All targets in OG5_126768
Brugia malayi Cathepsin L-like precursor Get druggable targets OG5_126607 All targets in OG5_126607
Onchocerca volvulus Get druggable targets OG5_126607 All targets in OG5_126607
Theileria parva cysteine protease, putative Get druggable targets OG5_126607 All targets in OG5_126607
Trypanosoma congolense cysteine peptidase, Clan CA, family C1, Cathepsin L-like Get druggable targets OG5_126607 All targets in OG5_126607
Echinococcus granulosus cathepsin l1 Get druggable targets OG5_126607 All targets in OG5_126607
Brugia malayi Intermediate filament tail domain containing protein Get druggable targets OG5_128723 All targets in OG5_128723
Brugia malayi Cathepsin L-like precursor Get druggable targets OG5_126607 All targets in OG5_126607
Leishmania braziliensis cathepsin L-like protease Get druggable targets OG5_126607 All targets in OG5_126607
Leishmania infantum cathepsin L-like protease Get druggable targets OG5_126607 All targets in OG5_126607
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like Get druggable targets OG5_126607 All targets in OG5_126607
Giardia lamblia Endonuclease/Exonuclease/phosphatase Get druggable targets OG5_126768 All targets in OG5_126768
Leishmania mexicana Get druggable targets OG5_126607 All targets in OG5_126607
Trypanosoma congolense cysteine peptidase, Clan CA, family C1, Cathepsin L-like Get druggable targets OG5_126607 All targets in OG5_126607
Echinococcus multilocularis cysteine protease Get druggable targets OG5_126607 All targets in OG5_126607
Brugia malayi Cathepsin L-like precursor Get druggable targets OG5_126607 All targets in OG5_126607
Trypanosoma congolense cysteine peptidase, Clan CA, family C1, Cathepsin L-like Get druggable targets OG5_126607 All targets in OG5_126607
Neospora caninum hypothetical protein Get druggable targets OG5_126768 All targets in OG5_126768
Entamoeba histolytica cysteine proteinase, putative Get druggable targets OG5_126607 All targets in OG5_126607
Leishmania major cathepsin L-like protease Get druggable targets OG5_126607 All targets in OG5_126607
Brugia malayi cathepsin L-like precursor Get druggable targets OG5_126607 All targets in OG5_126607
Trichomonas vaginalis ap endonuclease, putative Get druggable targets OG5_126768 All targets in OG5_126768
Brugia malayi Cathepsin L-like precursor Get druggable targets OG5_126607 All targets in OG5_126607
Cryptosporidium parvum conserved hypothetical protein Get druggable targets OG5_126768 All targets in OG5_126768
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like Get druggable targets OG5_126607 All targets in OG5_126607
Echinococcus multilocularis cathepsin L cysteine protease Get druggable targets OG5_126607 All targets in OG5_126607
Toxoplasma gondii exonuclease III APE Get druggable targets OG5_126768 All targets in OG5_126768
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase Get druggable targets OG5_126607 All targets in OG5_126607
Echinococcus granulosus cathepsin l cysteine peptidase Get druggable targets OG5_126607 All targets in OG5_126607
Plasmodium falciparum AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative Get druggable targets OG5_126768 All targets in OG5_126768
Loa Loa (eye worm) papain family cysteine protease containing protein Get druggable targets OG5_126607 All targets in OG5_126607
Onchocerca volvulus Get druggable targets OG5_126607 All targets in OG5_126607
Leishmania major cathepsin L-like protease Get druggable targets OG5_126607 All targets in OG5_126607
Schistosoma japonicum ko:K01373 cathepsin F [EC3.4.22.41], putative Get druggable targets OG5_126607 All targets in OG5_126607
Plasmodium vivax vivapain-2 Get druggable targets OG5_126607 All targets in OG5_126607
Echinococcus multilocularis musashi Get druggable targets OG5_128723 All targets in OG5_128723
Onchocerca volvulus Get druggable targets OG5_128723 All targets in OG5_128723
Schistosoma japonicum DNA-(apurinic or apyrimidinic site) lyase 2, putative Get druggable targets OG5_126768 All targets in OG5_126768
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase Get druggable targets OG5_126768 All targets in OG5_126768
Onchocerca volvulus Get druggable targets OG5_126607 All targets in OG5_126607
Echinococcus multilocularis lamin dm0 Get druggable targets OG5_128723 All targets in OG5_128723
Leishmania major cathepsin L-like protease Get druggable targets OG5_126607 All targets in OG5_126607
Onchocerca volvulus Get druggable targets OG5_126607 All targets in OG5_126607
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_128723 All targets in OG5_128723
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase Get druggable targets OG5_126607 All targets in OG5_126607
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_126607 All targets in OG5_126607
Leishmania mexicana Get druggable targets OG5_126607 All targets in OG5_126607
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase Get druggable targets OG5_126607 All targets in OG5_126607
Trypanosoma congolense cysteine peptidase, Clan CA, family C1, Cathepsin L-like Get druggable targets OG5_126607 All targets in OG5_126607
Echinococcus granulosus cathepsin l1 Get druggable targets OG5_126607 All targets in OG5_126607
Schistosoma mansoni ap endonuclease Get druggable targets OG5_126768 All targets in OG5_126768
Echinococcus multilocularis cathepsin l cysteine peptidase Get druggable targets OG5_126607 All targets in OG5_126607
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase Get druggable targets OG5_126607 All targets in OG5_126607
Loa Loa (eye worm) Papain cysteine protease/cathepsin propeptide inhibitor-containing protein Get druggable targets OG5_126607 All targets in OG5_126607
Echinococcus multilocularis cathepsin L cysteine protease Get druggable targets OG5_126607 All targets in OG5_126607
Trypanosoma congolense cysteine peptidase, Clan CA, family C1, Cathepsin L-like Get druggable targets OG5_126607 All targets in OG5_126607
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase Get druggable targets OG5_126607 All targets in OG5_126607
Leishmania mexicana cysteine peptidase A (CBA) Get druggable targets OG5_126607 All targets in OG5_126607
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase Get druggable targets OG5_126607 All targets in OG5_126607
Onchocerca volvulus Cathepsin L homolog Get druggable targets OG5_126607 All targets in OG5_126607
Schistosoma mansoni ap endonuclease Get druggable targets OG5_126768 All targets in OG5_126768
Plasmodium vivax AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative Get druggable targets OG5_126768 All targets in OG5_126768
Echinococcus multilocularis lamin Get druggable targets OG5_128723 All targets in OG5_128723
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_128723 All targets in OG5_128723
Leishmania braziliensis cathepsin L-like protease Get druggable targets OG5_126607 All targets in OG5_126607
Trypanosoma congolense apurinic/apyrimidinic endonuclease, putative Get druggable targets OG5_126768 All targets in OG5_126768
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase Get druggable targets OG5_126607 All targets in OG5_126607
Leishmania braziliensis cysteine peptidase A (CPA) Get druggable targets OG5_126607 All targets in OG5_126607
Plasmodium knowlesi knowpain-4 Get druggable targets OG5_126607 All targets in OG5_126607
Cryptosporidium parvum cryptopain - cysteine proteinase secreted, possible transmembrane domain near N-terminus Get druggable targets OG5_126607 All targets in OG5_126607
Brugia malayi intermediate filament protein Get druggable targets OG5_128723 All targets in OG5_128723
Echinococcus granulosus intermediate filament protein Get druggable targets OG5_128723 All targets in OG5_128723
Theileria parva hypothetical protein Get druggable targets OG5_126768 All targets in OG5_126768
Brugia malayi Cathepsin L-like cysteine proteinase Get druggable targets OG5_126607 All targets in OG5_126607
Cryptosporidium hominis dna-(apurinic or apyrimidinic site) lyase Get druggable targets OG5_126768 All targets in OG5_126768
Entamoeba histolytica exodeoxyribonuclease III, putative Get druggable targets OG5_126768 All targets in OG5_126768
Onchocerca volvulus Cathepsin F homolog Get druggable targets OG5_126607 All targets in OG5_126607
Trypanosoma cruzi cysteine peptidase, putative Get druggable targets OG5_126607 All targets in OG5_126607
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_128723 All targets in OG5_128723
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase Get druggable targets OG5_126607 All targets in OG5_126607
By sequence similarity to non orthologous known druggable targets
Species Potential target Known druggable target Length Alignment span Identity
Loa Loa (eye worm) pigment dispersing factor receptor c glucagon-like peptide 1 receptor 463 aa 388 aa 25.8 %
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0014 0.0107 0.0163
Mycobacterium tuberculosis Conserved protein 0.0038 0.0629 0.1214
Brugia malayi Cathepsin L-like precursor 0.0014 0.0107 0.0157
Schistosoma mansoni hypothetical protein 0.0371 0.7683 0.8736
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0077 0.1453 1
Toxoplasma gondii cathepsin CPL 0.002 0.0248 0.2195
Onchocerca volvulus 0.003 0.045 0.0863
Echinococcus multilocularis cysteine protease 0.002 0.0248 0.0248
Loa Loa (eye worm) histone methyltransferase 0.001 0.0038 0.0023
Schistosoma mansoni hypothetical protein 0.0019 0.0224 0.0254
Trichomonas vaginalis D-aminoacylase, putative 0.0038 0.0629 0.1227
Loa Loa (eye worm) hypothetical protein 0.0038 0.0629 0.1179
Loa Loa (eye worm) ctsf protein 0.002 0.0248 0.0435
Echinococcus granulosus cation transporting atpase worm 0.001 0.0027 0.0027
Trypanosoma cruzi cysteine protease, putative 0.001 0.0041 0.0099
Leishmania major cathepsin L-like protease 0.002 0.0248 0.1556
Brugia malayi exodeoxyribonuclease III family protein 0.0023 0.0301 0.0538
Trichomonas vaginalis nADP transhydrogenase, putative 0.0017 0.0174 0.0301
Entamoeba histolytica cysteine proteinase 1, putative 0.001 0.0041 0.0048
Trypanosoma brucei JmjC domain, hydroxylase, putative 0.0018 0.0203 0.124
Schistosoma mansoni phd/f-box containing protein 0.0018 0.0203 0.0231
Mycobacterium tuberculosis Possible dehydrogenase 0.0149 0.2969 0.5931
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0019 0.0224 0.0224
Trichomonas vaginalis nADP transhydrogenase, putative 0.0017 0.0174 0.0301
Loa Loa (eye worm) follicle stimulating hormone receptor 0.0236 0.4813 0.9375
Echinococcus granulosus cpg binding protein 0.0031 0.0486 0.0486
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0077 0.1453 1
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.0038 0.0629 0.1214
Echinococcus granulosus lysine specific demethylase 6a 0.0018 0.0203 0.0203
Echinococcus granulosus plasma membrane calcium transporting ATPase 2 0.001 0.0027 0.0027
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0064 0.118 0.1342
Entamoeba histolytica NAD(P)( ) transhydrogenase (AB-specific), alpha subunit, putative 0.0017 0.0174 0.0503
Entamoeba histolytica cysteine proteinase 2 0.001 0.0041 0.0048
Trichomonas vaginalis alcohol dehydrogenase, putative 0.0149 0.2969 0.5996
Echinococcus granulosus calcium transporting ATPase type 2C member 0.001 0.0027 0.0027
Schistosoma mansoni hypothetical protein 0.0041 0.0692 0.0787
Plasmodium falciparum pyridine nucleotide transhydrogenase, putative 0.0017 0.0174 0.5384
Trypanosoma cruzi cysteine peptidase (N-terminal), putative 0.001 0.0041 0.0099
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0047 0.0823 0.0823
Echinococcus granulosus GPCR family 2 0.0019 0.0224 0.0224
Schistosoma mansoni transcription factor LCR-F1 0.0079 0.1489 0.1693
Onchocerca volvulus 0.002 0.0248 0.0452
Echinococcus granulosus cytoplasmic intermediate filament protein 0.0016 0.0153 0.0153
Loa Loa (eye worm) fibroinase 0.002 0.0248 0.0435
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.0023 0.0301 0.0301
Brugia malayi cathepsin L-like precursor 0.0014 0.0107 0.0157
Schistosoma mansoni phosphoserine phosphatase 0.001 0.0027 0.003
Echinococcus granulosus lamin dm0 0.0033 0.051 0.051
Brugia malayi jmjC domain containing protein 0.007 0.1294 0.2483
Schistosoma mansoni eyes absent homolog 0.0102 0.1975 0.2246
Mycobacterium tuberculosis Probable lipase LipD 0.0038 0.0629 0.1214
Loa Loa (eye worm) hypothetical protein 0.0038 0.0629 0.1179
Schistosoma mansoni survival motor neuron protein 0.0051 0.0903 0.1027
Echinococcus multilocularis cation transporting ATPase 13A3 0.001 0.0027 0.0027
Plasmodium falciparum JmjC domain-containing protein, putative 0.0018 0.0203 0.644
Loa Loa (eye worm) hypothetical protein 0.0038 0.0629 0.1179
Brugia malayi Papain family cysteine protease containing protein 0.001 0.0041 0.0028
Loa Loa (eye worm) hypothetical protein 0.0038 0.0629 0.1179
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0038 0.0629 0.0715
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.002 0.0248 0.0452
Mycobacterium leprae PROBABLE NAD(P) TRANSHYDROGENASE (SUBUNIT ALPHA) PNTAA [FIRST PART; CATALYTIC PART] (PYRIDINE NUCLEOTIDE TRANSHYDROGENASE SUBUNI 0.0017 0.0174 0.2456
Onchocerca volvulus 0.002 0.0248 0.0452
Echinococcus granulosus sarco:endoplasmic reticulum calcium ATPase 0.001 0.0027 0.0027
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0077 0.1453 1
Leishmania major cathepsin L-like protease 0.0077 0.1453 1
Mycobacterium ulcerans NAD(P) transhydrogenase PntA 0.0017 0.0174 0.0503
Schistosoma mansoni hypothetical protein 0.0371 0.7683 0.8736
Echinococcus multilocularis neuropeptide s receptor 0.048 1 1
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0077 0.1453 1
Echinococcus granulosus cathepsin l1 0.002 0.0248 0.0248
Loa Loa (eye worm) cytoplasmic intermediate filament protein 0.0017 0.019 0.0319
Loa Loa (eye worm) hypothetical protein 0.0014 0.0107 0.0157
Schistosoma mansoni ubiquitously transcribed sex (X/Y) chromosome tetratricopeptide repeat protein-related 0.0018 0.0203 0.0231
Mycobacterium ulcerans exodeoxyribonuclease III protein XthA 0.0023 0.0301 0.0934
Plasmodium vivax vivapain-2 0.002 0.0248 0.3685
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0079 0.1489 0.1489
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0077 0.1453 1
Echinococcus multilocularis lysine specific demethylase 5A 0.0068 0.1258 0.1258
Toxoplasma gondii histone lysine demethylase JMJC1/KDM5D/JARID1D 0.0018 0.0203 0.175
Echinococcus granulosus geminin 0.0371 0.7683 0.7683
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0212 0.4315 0.8399
Toxoplasma gondii alanine dehydrogenase 0.0017 0.0174 0.1463
Entamoeba histolytica cysteine protease, putative 0.002 0.0248 0.0754
Wolbachia endosymbiont of Brugia malayi exonuclease III 0.0023 0.0301 0.5
Echinococcus granulosus cathepsin L 0.001 0.0041 0.0041
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.002 0.0248 0.0452
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0019 0.0224 0.0224
Mycobacterium ulcerans hypothetical protein 0.0038 0.0629 0.2046
Entamoeba histolytica hypothetical protein 0.0079 0.1489 0.4971
Entamoeba histolytica cysteine protease, putative 0.001 0.0041 0.0048
Entamoeba histolytica cysteine proteinase, putative 0.002 0.0248 0.0754
Echinococcus granulosus cysteine protease 0.001 0.0041 0.0041
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0038 0.0629 0.0715
Loa Loa (eye worm) hypothetical protein 0.0251 0.5132 1
Loa Loa (eye worm) hypothetical protein 0.0014 0.0107 0.0157
Loa Loa (eye worm) jmjC domain-containing protein 0.007 0.1294 0.2483
Mycobacterium ulcerans lipase LipD 0.0038 0.0629 0.2046
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.001 0.0038 0.0038
Schistosoma mansoni jumonji/arid domain-containing protein 0.007 0.1294 0.1472
Entamoeba histolytica cysteine protease, putative 0.001 0.0041 0.0048
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.001 0.0041 0.0029
Loa Loa (eye worm) hypothetical protein 0.0032 0.0498 0.0922
Brugia malayi Cathepsin L-like precursor 0.002 0.0248 0.0435
Entamoeba histolytica cysteine protease, putative 0.001 0.0041 0.0048
Echinococcus multilocularis phospholipid transporting ATPase IIB 0.001 0.0027 0.0027
Loa Loa (eye worm) hypothetical protein 0.0033 0.051 0.0947
Mycobacterium tuberculosis Possible penicillin-binding protein 0.0244 0.4987 1
Brugia malayi beta-lactamase family protein 0.0038 0.0629 0.1179
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.0023 0.0301 0.0538
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.002 0.0248 0.0452
Schistosoma mansoni jumonji domain containing protein 0.0068 0.1258 0.1431
Echinococcus multilocularis phosphoserine phosphatase 0.001 0.0027 0.0027
Schistosoma mansoni intermediate filament proteins 0.0033 0.051 0.058
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.002 0.0248 0.0452
Schistosoma mansoni cation-transporting ATPase 0.001 0.0027 0.003
Toxoplasma gondii histone lysine methyltransferase SET1 0.0057 0.1037 1
Brugia malayi Latrophilin receptor protein 2 0.0019 0.0224 0.0386
Mycobacterium tuberculosis Probable lipase LipE 0.0038 0.0629 0.1214
Echinococcus multilocularis lamin dm0 0.0033 0.051 0.051
Echinococcus multilocularis cathepsin l cysteine peptidase 0.002 0.0248 0.0248
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.002 0.0248 0.0452
Loa Loa (eye worm) pigment dispersing factor receptor c 0.006 0.1096 0.2095
Echinococcus multilocularis survival motor neuron protein 1 0.0251 0.5132 0.5132
Echinococcus granulosus Transcription factor JmjC domain containing protein 0.0068 0.1258 0.1258
Echinococcus granulosus nadp transhydrogenase 0.0017 0.0174 0.0174
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.001 0.0041 0.0046
Echinococcus multilocularis cathepsin L 0.001 0.0041 0.0041
Echinococcus multilocularis phd:f box containing protein 0.0018 0.0203 0.0203
Echinococcus multilocularis lysine specific demethylase 6a 0.0018 0.0203 0.0203
Echinococcus granulosus beta LACTamase domain containing family member 0.0038 0.0629 0.0629
Loa Loa (eye worm) hypothetical protein 0.0038 0.0629 0.1179
Echinococcus multilocularis Jumonji, AT rich interactive domain 1B 0.002 0.0239 0.0239
Echinococcus granulosus cathepsin L cysteine proteinase 0.002 0.0248 0.0248
Plasmodium vivax pyridine nucleotide transhydrogenase, putative 0.0017 0.0174 0.2456
Echinococcus multilocularis cation transporting atpase worm 0.001 0.0027 0.0027
Schistosoma mansoni type V p-type atpase isoform 0.001 0.0027 0.003
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0038 0.0629 0.1179
Trichomonas vaginalis D-aminoacylase, putative 0.0038 0.0629 0.1227
Brugia malayi Papain family cysteine protease containing protein 0.001 0.0041 0.0028
Trypanosoma cruzi cysteine proteinase, putative 0.001 0.0041 0.0099
Echinococcus granulosus cation transporting ATPase 13A1 0.001 0.0027 0.0027
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.0038 0.0629 0.2046
Giardia lamblia Endonuclease/Exonuclease/phosphatase 0.0023 0.0301 1
Entamoeba histolytica cysteine proteinase, putative 0.001 0.0041 0.0048
Echinococcus multilocularis jumonji domain containing 1A 0.0018 0.0203 0.0203
Plasmodium vivax hypothetical protein, conserved 0.0038 0.0629 1
Schistosoma mansoni lamin 0.0033 0.051 0.058
Onchocerca volvulus 0.0038 0.0629 0.1227
Schistosoma mansoni ATPase 0.001 0.0027 0.003
Trichomonas vaginalis set domain proteins, putative 0.0241 0.4934 1
Onchocerca volvulus 0.0051 0.0903 0.1787
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0047 0.0823 0.1561
Echinococcus multilocularis cathepsin L cysteine protease 0.002 0.0248 0.0248
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0031 0.0476 0.0476
Schistosoma mansoni cation-transporting atpase 13a1 (G-box binding protein) 0.001 0.0027 0.003
Trypanosoma cruzi JmjC domain, hydroxylase, putative 0.0018 0.0203 0.124
Loa Loa (eye worm) hypothetical protein 0.0038 0.0629 0.1179
Schistosoma mansoni phosphatidylserine receptor 0.0018 0.0203 0.0231
Onchocerca volvulus 0.0033 0.051 0.0985
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.002 0.0248 0.0452
Loa Loa (eye worm) intermediate filament protein 0.0033 0.051 0.0947
Loa Loa (eye worm) papain family cysteine protease containing protein 0.002 0.0248 0.0435
Schistosoma mansoni cation-transporting atpase worm 0.001 0.0027 0.003
Treponema pallidum exodeoxyribonuclease (exoA) 0.0023 0.0301 1
Schistosoma mansoni ap endonuclease 0.0023 0.0301 0.0343
Entamoeba histolytica cysteine proteinase, putative 0.001 0.0041 0.0048
Onchocerca volvulus Cathepsin L homolog 0.002 0.0248 0.0452
Echinococcus multilocularis cation transporting ATPase 13A1 0.001 0.0027 0.0027
Leishmania major cysteine peptidase A (CPA) 0.002 0.0248 0.1556
Mycobacterium tuberculosis Conserved protein 0.0038 0.0629 0.1214
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.001 0.0041 0.0099
Echinococcus granulosus phd:f box containing protein 0.0018 0.0203 0.0203
Echinococcus multilocularis nadp transhydrogenase 0.0017 0.0174 0.0174
Brugia malayi intermediate filament protein 0.0033 0.051 0.0947
Echinococcus granulosus Jumonji AT rich interactive domain 1B 0.002 0.0239 0.0239
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.001 0.0041 0.0046
Brugia malayi jmjC domain containing protein 0.0068 0.1258 0.2413
Trypanosoma cruzi cysteine peptidase, putative 0.0077 0.1453 1
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0031 0.0476 0.0542
Echinococcus granulosus cathepsin l cysteine peptidase 0.002 0.0248 0.0248
Entamoeba histolytica hypothetical protein 0.0079 0.1489 0.4971
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.002 0.0248 0.0452
Brugia malayi Cathepsin L-like precursor 0.002 0.0248 0.0435
Trypanosoma cruzi hypothetical protein, conserved 0.0038 0.0629 0.4221
Brugia malayi jmjC domain containing protein 0.0018 0.0203 0.0346
Echinococcus granulosus phospholipid transporting ATPase IIB 0.001 0.0027 0.0027
Brugia malayi jmjC domain containing protein 0.0018 0.0203 0.0346
Mycobacterium ulcerans secreted L-alanine dehydrogenase Ald (40 kDa antigen) 0.0017 0.0174 0.0503
Trypanosoma cruzi hypothetical protein, conserved 0.0038 0.0629 0.4221
Plasmodium falciparum cysteine proteinase falcipain 3 0.002 0.0248 0.8078
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.0038 0.0629 0.1214
Trypanosoma cruzi major cysteine proteinase, putative 0.0061 0.1103 0.7549
Schistosoma mansoni ap endonuclease 0.0023 0.0301 0.0343
Schistosoma mansoni jumonji/arid domain-containing protein 0.007 0.1294 0.1472
Trypanosoma cruzi cysteine peptidase, putative 0.0077 0.1453 1
Echinococcus multilocularis beta LACTamase domain containing family member 0.0038 0.0629 0.0629
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.002 0.0248 0.0452
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.0023 0.0301 0.1926
Brugia malayi cytoplasmic intermediate filament protein 0.0017 0.019 0.0319
Brugia malayi Cathepsin L-like precursor 0.002 0.0248 0.0435
Entamoeba histolytica cysteine protease, putative 0.001 0.0041 0.0048
Echinococcus multilocularis phosphoserine phosphatase 0.001 0.0027 0.0027
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.002 0.0248 0.0452
Loa Loa (eye worm) hypothetical protein 0.0019 0.0224 0.0386
Echinococcus multilocularis phosphoserine phosphatase 0.001 0.0027 0.0027
Trichomonas vaginalis alcohol dehydrogenase, putative 0.0149 0.2969 0.5996
Trypanosoma cruzi cruzipain precursor, putative 0.0077 0.1453 1
Toxoplasma gondii histone lysine demethylase JMJD6a 0.0018 0.0203 0.175
Trichomonas vaginalis penicillin-binding protein, putative 0.0038 0.0629 0.1227
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0077 0.1453 1
Leishmania major apurinic/apyrimidinic endonuclease-redox protein 0.0023 0.0301 0.1926
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0077 0.1453 1
Onchocerca volvulus 0.002 0.0248 0.0452
Mycobacterium leprae conserved hypothetical protein 0.0038 0.0629 1
Echinococcus multilocularis lamin 0.0033 0.051 0.051
Echinococcus multilocularis cysteine protease 0.002 0.0248 0.0248
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0047 0.0823 0.0936
Echinococcus multilocularis cpg binding protein 0.0031 0.0486 0.0486
Toxoplasma gondii alanine dehydrogenase/pyridine nucleotide transhydrogenase domain-containing protein 0.0017 0.0174 0.1463
Brugia malayi Pre-SET motif family protein 0.0031 0.0476 0.0881
Plasmodium vivax vivapain-2 0.002 0.0248 0.3685
Plasmodium falciparum cysteine proteinase falcipain 2b 0.002 0.0248 0.8078
Brugia malayi CXXC zinc finger family protein 0.003 0.045 0.0829
Trypanosoma cruzi cysteine peptidase, putative 0.002 0.0248 0.1556
Leishmania major hypothetical protein, conserved 0.0038 0.0629 0.4221
Leishmania major cathepsin L-like protease 0.0077 0.1453 1
Brugia malayi Papain family cysteine protease containing protein 0.002 0.0248 0.0435
Brugia malayi Cathepsin L-like precursor 0.002 0.0248 0.0435
Loa Loa (eye worm) CXXC zinc finger family protein 0.003 0.045 0.0829
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.002 0.0248 0.0452
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0077 0.1453 1
Onchocerca volvulus Cathepsin F homolog 0.002 0.0248 0.0452
Brugia malayi jmjC domain containing protein 0.0018 0.0203 0.0346
Loa Loa (eye worm) latrophilin receptor protein 2 0.0019 0.0224 0.0386
Plasmodium vivax unspecified product 0.001 0.0041 0.0233
Brugia malayi Cathepsin L-like precursor 0.002 0.0248 0.0435
Schistosoma mansoni hypothetical protein 0.0019 0.0224 0.0254
Schistosoma mansoni cathepsin F (C01 family) 0.0014 0.0107 0.0121
Brugia malayi follicle stimulating hormone receptor 0.0236 0.4813 0.9375
Loa Loa (eye worm) hypothetical protein 0.0015 0.014 0.0223
Schistosoma mansoni lamin 0.0033 0.051 0.058
Schistosoma mansoni hypothetical protein 0.0019 0.0224 0.0254
Toxoplasma gondii NAD(P) transhydrogenase subunit beta, putative 0.0017 0.0174 0.1463
Echinococcus multilocularis phosphoserine phosphatase 0.001 0.0027 0.0027
Leishmania major cathepsin L-like protease 0.002 0.0248 0.1556
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.0051 0.0903 0.1717
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.002 0.0248 0.0452
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.002 0.0248 0.0452
Trichomonas vaginalis esterase, putative 0.0038 0.0629 0.1227
Schistosoma mansoni cpg binding protein 0.0031 0.0486 0.0552
Loa Loa (eye worm) hypothetical protein 0.006 0.1096 0.2095
Plasmodium falciparum cysteine proteinase falcipain 1 0.001 0.0041 0.0512
Schistosoma mansoni hypothetical protein 0.0423 0.8794 1
Entamoeba histolytica NAD(P) transhydrogenase subunit alpha, putative 0.0017 0.0174 0.0503
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0079 0.1489 0.1489
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0047 0.0823 0.0823
Leishmania major cathepsin L-like protease 0.0077 0.1453 1
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.002 0.0248 0.0452
Echinococcus multilocularis copper transporting ATPase 1 0.001 0.0027 0.0027
Onchocerca volvulus 0.002 0.0248 0.0452
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0031 0.0476 0.0542
Echinococcus multilocularis calcium transporting ATPase type 2C member 0.001 0.0027 0.0027
Schistosoma mansoni cpg binding protein 0.0031 0.0486 0.0552
Entamoeba histolytica cysteine protease, putative 0.001 0.0041 0.0048
Brugia malayi Cathepsin L-like precursor 0.0014 0.0107 0.0157
Mycobacterium ulcerans esterase/lipase LipP 0.0038 0.0629 0.2046
Entamoeba histolytica hypothetical protein 0.0079 0.1489 0.4971
Schistosoma mansoni hypothetical protein 0.0019 0.0224 0.0254
Plasmodium falciparum cysteine proteinase falcipain 2a 0.002 0.0248 0.8078
Mycobacterium tuberculosis Probable esterase LipL 0.0038 0.0629 0.1214
Onchocerca volvulus 0.0038 0.0629 0.1227
Entamoeba histolytica cysteine protease, putative 0.001 0.0041 0.0048
Echinococcus multilocularis Tetracycline resistance leader peptide, TetL 0.001 0.0027 0.0027
Mycobacterium leprae SECRETED L-ALANINE DEHYDROGENASE ALD (40 KDA ANTIGEN) (TB43) 0.0017 0.0174 0.2456
Brugia malayi hypothetical protein 0.0079 0.1489 0.2865
Echinococcus granulosus lysine specific demethylase 5A 0.007 0.1294 0.1294
Trichomonas vaginalis D-aminoacylase, putative 0.0038 0.0629 0.1227
Schistosoma mansoni hypothetical protein 0.0079 0.1489 0.1693
Loa Loa (eye worm) hypothetical protein 0.0018 0.0203 0.0346
Trypanosoma brucei hypothetical protein, conserved 0.0038 0.0629 0.4221
Loa Loa (eye worm) hypothetical protein 0.0102 0.1975 0.3817
Brugia malayi jmjC domain containing protein 0.0018 0.0203 0.0346
Echinococcus multilocularis dnaJ subfamily B 0.0423 0.8794 0.8794
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.006 0.1096 0.2095
Plasmodium falciparum AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0023 0.0301 1
Leishmania major cathepsin L-like protease 0.002 0.0248 0.1556
Trichomonas vaginalis alcohol dehydrogenase, putative 0.0149 0.2969 0.5996
Echinococcus granulosus JmjC domain containing protein 4 0.0018 0.0203 0.0203
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0031 0.0476 0.445
Echinococcus granulosus intermediate filament protein 0.0033 0.051 0.051
Echinococcus multilocularis geminin 0.0371 0.7683 0.7683
Entamoeba histolytica exodeoxyribonuclease III, putative 0.0023 0.0301 0.0934
Echinococcus granulosus lamin 0.0033 0.051 0.051
Brugia malayi beta-lactamase family protein 0.0038 0.0629 0.1179
Trichomonas vaginalis penicillin-binding protein, putative 0.0038 0.0629 0.1227
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.002 0.0248 0.0452
Schistosoma mansoni cation-transporting atpase worm 0.001 0.0027 0.003
Entamoeba histolytica cysteine protease, putative 0.001 0.0041 0.0048
Leishmania major hypothetical protein, conserved 0.0018 0.0203 0.124
Brugia malayi Pre-SET motif family protein 0.0212 0.4315 0.8399
Entamoeba histolytica cysteine proteinase, putative 0.001 0.0041 0.0048
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.002 0.0248 0.0452
Entamoeba histolytica cysteine protease, putative 0.001 0.0041 0.0048
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.0033 0.051 0.0947
Brugia malayi F/Y-rich N-terminus family protein 0.001 0.0036 0.0018
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.002 0.0248 0.0452
Echinococcus granulosus phospholipid transporting ATPase VA 0.001 0.0027 0.0027
Schistosoma mansoni jumonji domain containing protein 0.0018 0.0203 0.0231
Trypanosoma cruzi cysteine proteinase, putative 0.001 0.0041 0.0099
Loa Loa (eye worm) jmjC domain-containing protein 0.0018 0.0203 0.0346
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0014 0.0107 0.0163
Onchocerca volvulus 0.0031 0.0476 0.0917
Brugia malayi Cathepsin L-like precursor 0.002 0.0248 0.0435
Trypanosoma cruzi cysteine peptidase, putative 0.001 0.0041 0.0099
Brugia malayi Calcitonin receptor-like protein seb-1 0.006 0.1096 0.2095
Schistosoma mansoni NADP transhydrogenase 0.0017 0.0174 0.0198
Entamoeba histolytica hypothetical protein 0.0079 0.1489 0.4971
Echinococcus granulosus cathepsin L cysteine protease 0.001 0.0041 0.0041
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative 0.0023 0.0301 0.1926
Schistosoma mansoni cathepsin F (C01 family) 0.002 0.0248 0.0282
Plasmodium vivax vivapain-1 0.001 0.0041 0.0233
Echinococcus multilocularis musashi 0.0033 0.051 0.051
Mycobacterium tuberculosis Probable NAD(P) transhydrogenase (subunit alpha) PntAa [first part; catalytic part] (pyridine nucleotide transhydrogenase subuni 0.0017 0.0174 0.0298
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0047 0.0823 0.0823
Echinococcus granulosus neuropeptide receptor A26 0.048 1 1
Loa Loa (eye worm) hypothetical protein 0.0016 0.0153 0.0248
Echinococcus multilocularis phospholipid transporting ATPase VA 0.001 0.0027 0.0027
Brugia malayi latrophilin 2 splice variant baaae 0.0041 0.0692 0.1304
Toxoplasma gondii exonuclease III APE 0.0023 0.0301 0.2718
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.002 0.0248 0.0452
Mycobacterium ulcerans dehydrogenase 0.0149 0.2969 1
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0019 0.0224 0.0224
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.002 0.0248 0.0452
Leishmania major cathepsin L-like protease 0.002 0.0248 0.1556
Trypanosoma cruzi apurinic/apyrimidinic endonuclease 0.0023 0.0301 0.1926
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0047 0.0823 0.0936
Loa Loa (eye worm) hypothetical protein 0.0031 0.0476 0.0881
Mycobacterium leprae Probable lipase LipE 0.0038 0.0629 1
Loa Loa (eye worm) hypothetical protein 0.0102 0.1975 0.3817
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.001 0.0038 0.0038
Echinococcus granulosus cation transporting ATPase 13A3 0.001 0.0027 0.0027
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.001 0.0041 0.0046
Loa Loa (eye worm) beta-lactamase 0.0038 0.0629 0.1179
Loa Loa (eye worm) Papain cysteine protease/cathepsin propeptide inhibitor-containing protein 0.002 0.0248 0.0435
Schistosoma mansoni Na+/K+ transporting ATPase subunit alpha 0.001 0.0027 0.003
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0029 0.0439 0.0439
Loa Loa (eye worm) jmjC domain-containing protein 0.0018 0.0203 0.0346
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0047 0.0823 0.0936
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0047 0.0823 0.1561
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0038 0.0629 0.1179
Loa Loa (eye worm) hypothetical protein 0.0041 0.0692 0.1304
Onchocerca volvulus 0.0038 0.0629 0.1227
Loa Loa (eye worm) jmjC domain-containing protein 0.0018 0.0203 0.0346
Entamoeba histolytica cysteine protease, putative 0.001 0.0041 0.0048
Onchocerca volvulus Cathepsin L homolog 0.002 0.0248 0.0452
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.0023 0.0301 0.0301
Plasmodium vivax SET domain protein, putative 0.0031 0.0476 0.7471
Chlamydia trachomatis metal transport ATPase 0.001 0.0027 0.5
Echinococcus multilocularis Transcription factor, JmjC domain containing protein 0.0068 0.1258 0.1258
Mycobacterium tuberculosis Probable hydrolase 0.0038 0.0629 0.1214
Echinococcus multilocularis phosphoserine phosphatase 0.001 0.0027 0.0027
Plasmodium vivax vivapain-3 0.001 0.0041 0.0233
Plasmodium vivax AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0023 0.0301 0.4562
Echinococcus multilocularis GPCR, family 2 0.0019 0.0224 0.0224
Entamoeba histolytica cysteine protease, putative 0.001 0.0041 0.0048
Trichomonas vaginalis ap endonuclease, putative 0.0023 0.0301 0.056
Trypanosoma cruzi cysteine peptidase, clan CA, family C1, cathepsin L-like, putative 0.007 0.1311 0.9007
Onchocerca volvulus 0.0033 0.051 0.0985
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0077 0.1453 1
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0031 0.0476 0.0542
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0077 0.1453 1
Schistosoma mansoni protein phosphatase 2C 0.0018 0.0203 0.0231
Echinococcus multilocularis sarco:endoplasmic reticulum calcium ATPase 0.001 0.0027 0.0027
Onchocerca volvulus 0.0014 0.0107 0.0163
Mycobacterium ulcerans beta-lactamase 0.0038 0.0629 0.2046
Schistosoma mansoni copper ABC transporter ATPase 0.001 0.0027 0.003
Brugia malayi beta-lactamase 0.0038 0.0629 0.1179
Mycobacterium tuberculosis Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) 0.0023 0.0301 0.0554
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.002 0.0248 0.0452
Echinococcus multilocularis cytoplasmic intermediate filament protein 0.0016 0.0153 0.0153
Loa Loa (eye worm) hypothetical protein 0.0018 0.0203 0.0346
Entamoeba histolytica cysteine proteinase, putative 0.002 0.0248 0.0754
Leishmania major cathepsin L-like protease 0.002 0.0248 0.1556
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.002 0.0248 0.0452
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.002 0.0248 0.0452
Entamoeba histolytica cysteine proteinase, putative 0.0014 0.0107 0.0273
Schistosoma mansoni cathepsin F (C01 family) 0.002 0.0248 0.0282
Echinococcus granulosus survival motor neuron protein 1 0.0251 0.5132 0.5132
Entamoeba histolytica cysteine protease, putative 0.001 0.0041 0.0048
Loa Loa (eye worm) hypothetical protein 0.0015 0.014 0.0223
Mycobacterium tuberculosis Conserved protein 0.0038 0.0629 0.1214
Mycobacterium tuberculosis Probable conserved lipoprotein 0.0038 0.0629 0.1214
Entamoeba histolytica cysteine protease, putative 0.001 0.0041 0.0048
Schistosoma mansoni cpg binding protein 0.003 0.045 0.0512
Echinococcus multilocularis neuropeptide receptor A26 0.048 1 1
Schistosoma mansoni ATPase 0.001 0.0027 0.003
Loa Loa (eye worm) cysteine protease 0.002 0.0248 0.0435
Brugia malayi hypothetical protein 0.0102 0.1975 0.3817
Loa Loa (eye worm) hypothetical protein 0.002 0.0248 0.0435
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.001 0.0041 0.0099
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.002 0.0248 0.0452
Brugia malayi hypothetical protein 0.0251 0.5132 1
Echinococcus multilocularis cathepsin l cysteine peptidase 0.002 0.0248 0.0248
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0019 0.0224 0.0386
Onchocerca volvulus 0.002 0.0248 0.0452
Echinococcus multilocularis phosphoserine phosphatase 0.001 0.0027 0.0027
Trypanosoma cruzi cysteine peptidase, putative 0.0077 0.1453 1
Entamoeba histolytica NADP-dependent alcohol dehydrogenase, putative 0.0149 0.2969 1
Entamoeba histolytica cysteine protease, putative 0.001 0.0041 0.0048
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.001 0.0041 0.0029
Onchocerca volvulus 0.002 0.0248 0.0452
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0077 0.1453 1
Toxoplasma gondii ABC1 family protein 0.0038 0.0629 0.5957
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0019 0.0224 0.0224
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0047 0.0823 0.0823
Brugia malayi Cathepsin L-like cysteine proteinase 0.0014 0.0107 0.0157
Echinococcus multilocularis JmjC domain containing protein 4 0.0018 0.0203 0.0203
Schistosoma mansoni hypothetical protein 0.0051 0.0903 0.1027
Trypanosoma cruzi JmjC domain, hydroxylase, putative 0.0018 0.0203 0.124
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0031 0.0476 0.0476
Onchocerca volvulus 0.002 0.0248 0.0452
Onchocerca volvulus 0.0241 0.4934 1
Echinococcus granulosus jumonji domain containing 1A 0.0018 0.0203 0.0203
Trichomonas vaginalis ap endonuclease, putative 0.0023 0.0301 0.056
Loa Loa (eye worm) hypothetical protein 0.0018 0.0203 0.0346
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.002 0.0248 0.0452
Echinococcus granulosus copper transporting ATPase 1 0.001 0.0027 0.0027
Plasmodium vivax JmjC domain containing protein 0.0018 0.0203 0.2938
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0031 0.0476 0.0542
Echinococcus granulosus histone lysine methyltransferase setb 0.0031 0.0476 0.0476
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.002 0.0248 0.0452
Loa Loa (eye worm) hypothetical protein 0.0014 0.0107 0.0157
Mycobacterium tuberculosis Secreted L-alanine dehydrogenase Ald (40 kDa antigen) (TB43) 0.0017 0.0174 0.0298
Entamoeba histolytica cysteine proteinase, putative 0.001 0.0041 0.0048
Echinococcus multilocularis cathepsin L cysteine protease 0.002 0.0248 0.0248
Schistosoma mansoni atpase class VI type 11c 0.001 0.0027 0.003
Brugia malayi Intermediate filament tail domain containing protein 0.0033 0.051 0.0947
Echinococcus granulosus dnaJ subfamily B 0.0423 0.8794 0.8794
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.002 0.0248 0.0452
Echinococcus granulosus cathepsin l1 0.0014 0.0107 0.0107

Activities

Activity type Activity value Assay description Source Reference
Potency (functional) 0.2936 uM PUBCHEM_BIOASSAY: Primary qHTS for delayed death inhibitors of the malarial parasite plastid, 96 hour incubation. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID488745, AID488752, AID488774, AID504848, AID504850] ChEMBL. No reference
Potency (functional) 1 uM PubChem BioAssay. qHTS Assay for Inhibitors of the Human Apurinic/apyrimidinic Endonuclease 1 (APE1). (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) = 5.0119 um PUBCHEM_BIOASSAY: qHTS Assay for Promiscuous and Specific Inhibitors of Cruzain (without detergent). (Class of assay: confirmatory) [Related pubchem assays: 2158 (Confirmation qHTS Assay for Inhibitors of Cruzain), 2249 (Probe Development Summary of Promiscuous Inhibitors (Artifacts) of Cruzain), 2161 (qHTS Assay for Inhibitors of Papain: Counterscreen for Cruzain Assay), 1478 (qHTS Assay for Promiscuous and Specific Inhibitors of Cruzain (with detergent))] ChEMBL. No reference
Potency (functional) 5.8048 uM PUBCHEM_BIOASSAY: Nrf2 qHTS screen for inhibitors. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID493153, AID493163, AID504648] ChEMBL. No reference
Potency (functional) = 6.3096 um PUBCHEM_BIOASSAY: qHTS Assay for Modulators of Lamin A Splicing. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) 6.3096 uM PubChem BioAssay. qHTS of GLP-1 Receptor Inverse Agonists (Inhibition Mode). (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) 89.1251 uM PUBCHEM_BIOASSAY: qHTS for Inhibitors of Polymerase Iota. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID588623] ChEMBL. No reference

Phenotypes

Whole-cell/tissue/organism interactions

Species name Source Reference Is orphan
Plasmodium falciparum ChEMBL23

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

Bibliographic References

No literature references available for this target.

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