Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Echinococcus multilocularis | mixed lineage leukemia protein mll | 0.0008 | 0.0016 | 0.0016 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0015 | 0.0099 | 0.0344 |
Entamoeba histolytica | acyl-coA synthetase, putative | 0.0023 | 0.0208 | 0.5016 |
Onchocerca volvulus | 0.003 | 0.0294 | 0.1026 | |
Mycobacterium ulcerans | dihydrolipoamide dehydrogenase | 0.0013 | 0.0073 | 0.0193 |
Brugia malayi | Pre-SET motif family protein | 0.003 | 0.0293 | 0.1165 |
Trypanosoma brucei | dihydrolipoamide dehydrogenase | 0.0013 | 0.0073 | 0.1953 |
Plasmodium falciparum | ataxin-2 like protein, putative | 0.0026 | 0.024 | 0.0635 |
Schistosoma mansoni | chromobox protein | 0.0011 | 0.0055 | 0.011 |
Loa Loa (eye worm) | ImpB/MucB/SamB family protein | 0.0019 | 0.0153 | 0.0611 |
Brugia malayi | ImpB/MucB/SamB family protein | 0.0019 | 0.0153 | 0.0611 |
Echinococcus granulosus | thioredoxin glutathione reductase | 0.0037 | 0.038 | 0.0761 |
Schistosoma mansoni | mixed-lineage leukemia protein mll | 0.0008 | 0.0016 | 0.0032 |
Loa Loa (eye worm) | hypothetical protein | 0.0039 | 0.0399 | 0.159 |
Loa Loa (eye worm) | hypothetical protein | 0.0023 | 0.0208 | 0.083 |
Echinococcus multilocularis | chromobox protein 1 | 0.0069 | 0.078 | 0.078 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0045 | 0.0482 | 0.0965 |
Trypanosoma brucei | dihydrolipoamide dehydrogenase, point mutation | 0.0013 | 0.0073 | 0.1953 |
Mycobacterium ulcerans | acyl-CoA synthetase | 0.0023 | 0.0208 | 0.0551 |
Echinococcus granulosus | dnaJ subfamily B | 0.0403 | 0.5001 | 1 |
Mycobacterium ulcerans | acyl-CoA synthetase | 0.0023 | 0.0208 | 0.0551 |
Plasmodium falciparum | glutathione reductase | 0.0037 | 0.0374 | 0.0991 |
Trypanosoma cruzi | DNA polymerase kappa, putative | 0.0019 | 0.0153 | 0.4101 |
Mycobacterium tuberculosis | Probable fatty-acid-CoA ligase FadD3 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) | 0.0017 | 0.0122 | 0.0322 |
Echinococcus granulosus | Chromo domain | 0.0011 | 0.0055 | 0.011 |
Plasmodium falciparum | chromodomain-helicase-DNA-binding protein 1 homolog, putative | 0.0011 | 0.0055 | 0.0146 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0027 | 0.0257 | 0.0897 |
Entamoeba histolytica | hypothetical protein | 0.0035 | 0.0361 | 0.8691 |
Schistosoma mansoni | chromobox protein | 0.0069 | 0.078 | 0.156 |
Entamoeba histolytica | hypothetical protein | 0.0011 | 0.0055 | 0.1331 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.001 | 0.0036 | 0.0959 |
Trichomonas vaginalis | chromobox protein, putative | 0.0041 | 0.0436 | 0.1521 |
Brugia malayi | Valyl-tRNA synthetase | 0.0011 | 0.0055 | 0.022 |
Schistosoma mansoni | cpg binding protein | 0.003 | 0.0291 | 0.0582 |
Trichomonas vaginalis | chromodomain helicase DNA binding protein, putative | 0.0011 | 0.0055 | 0.0193 |
Trichomonas vaginalis | chromodomain helicase DNA binding protein, putative | 0.0018 | 0.0136 | 0.0475 |
Wolbachia endosymbiont of Brugia malayi | dihydrolipoamide dehydrogenase E3 component | 0.0013 | 0.0073 | 0.0099 |
Trypanosoma cruzi | DNA polymerase kappa, putative | 0.0019 | 0.0153 | 0.4101 |
Mycobacterium ulcerans | DNA polymerase IV | 0.0019 | 0.0153 | 0.0406 |
Plasmodium falciparum | acyl-CoA synthetase | 0.0017 | 0.0134 | 0.0354 |
Schistosoma mansoni | DNA polymerase eta | 0.0019 | 0.0153 | 0.0307 |
Schistosoma mansoni | chromodomain helicase DNA binding protein | 0.0011 | 0.0055 | 0.011 |
Trichomonas vaginalis | chromosome transmission fidelity factor, putative | 0.001 | 0.0036 | 0.0125 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0019 | 0.0153 | 0.4101 |
Loa Loa (eye worm) | hypothetical protein | 0.0026 | 0.024 | 0.0956 |
Trichomonas vaginalis | chromodomain helicase DNA binding protein, putative | 0.0014 | 0.0093 | 0.0323 |
Entamoeba histolytica | acyl-CoA synthetase, putative | 0.0023 | 0.0208 | 0.5016 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0013 | 0.0079 | 0.211 |
Echinococcus multilocularis | chromobox protein 1 | 0.0069 | 0.078 | 0.078 |
Loa Loa (eye worm) | CHromoDomain protein family member | 0.0013 | 0.0076 | 0.0301 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0045 | 0.0482 | 0.0482 |
Mycobacterium ulcerans | flavoprotein disulfide reductase | 0.0013 | 0.0073 | 0.0193 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.001 | 0.0036 | 0.0959 |
Entamoeba histolytica | deoxycytidyl transferase, putative | 0.0019 | 0.0153 | 0.3696 |
Onchocerca volvulus | 0.0011 | 0.0055 | 0.0193 | |
Mycobacterium tuberculosis | NAD(P)H quinone reductase LpdA | 0.0093 | 0.1082 | 0.2864 |
Trypanosoma cruzi | BRCA1 C Terminus (BRCT) domain containing protein, putative | 0.001 | 0.0036 | 0.0959 |
Entamoeba histolytica | chromodomain-helicase-DNA-binding protein, putative | 0.0011 | 0.0055 | 0.1331 |
Mycobacterium tuberculosis | Probable chain -fatty-acid-CoA ligase FadD13 (fatty-acyl-CoA synthetase) | 0.0023 | 0.0208 | 0.0551 |
Trypanosoma brucei | BRCA1 C Terminus (BRCT) domain containing protein, putative | 0.001 | 0.0036 | 0.0959 |
Brugia malayi | dihydrolipoyl dehydrogenase, mitochondrial precursor, putative | 0.0013 | 0.0073 | 0.0291 |
Trichomonas vaginalis | conserved hypothetical protein | 0.001 | 0.0036 | 0.0125 |
Schistosoma mansoni | histone-lysine n-methyltransferase setb1 | 0.003 | 0.0293 | 0.0585 |
Mycobacterium tuberculosis | Probable dehydrogenase | 0.0083 | 0.0965 | 0.2553 |
Trichomonas vaginalis | chromodomain helicase DNA binding protein, putative | 0.0018 | 0.0136 | 0.0475 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0013 | 0.0079 | 0.211 |
Loa Loa (eye worm) | hypothetical protein | 0.001 | 0.0036 | 0.0143 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0045 | 0.0482 | 0.0965 |
Echinococcus multilocularis | nibrin | 0.001 | 0.0036 | 0.0036 |
Entamoeba histolytica | fatty acid elongase, putative | 0.004 | 0.0415 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.001 | 0.0036 | 0.0143 |
Entamoeba histolytica | fatty acid elongase, putative | 0.004 | 0.0415 | 1 |
Schistosoma mansoni | transcription factor LCR-F1 | 0.0035 | 0.0361 | 0.0722 |
Mycobacterium ulcerans | acyl-CoA synthetase | 0.0023 | 0.0208 | 0.0551 |
Trichomonas vaginalis | chromodomain helicase DNA binding protein, putative | 0.0018 | 0.0136 | 0.0475 |
Leishmania major | 4-coumarate:coa ligase-like protein | 0.0023 | 0.0208 | 0.5567 |
Brugia malayi | hypothetical protein | 0.0026 | 0.024 | 0.0956 |
Schistosoma mansoni | topbp1 | 0.001 | 0.0036 | 0.0072 |
Loa Loa (eye worm) | hypothetical protein | 0.0011 | 0.0055 | 0.022 |
Loa Loa (eye worm) | hypothetical protein | 0.0017 | 0.0134 | 0.0533 |
Leishmania major | 2-oxoglutarate dehydrogenase, e3 component, lipoamidedehydrogenase-like protein | 0.0013 | 0.0073 | 0.1953 |
Loa Loa (eye worm) | hypothetical protein | 0.001 | 0.0036 | 0.0143 |
Loa Loa (eye worm) | pre-SET domain-containing protein family protein | 0.0206 | 0.251 | 1 |
Echinococcus multilocularis | dna polymerase eta | 0.0019 | 0.0153 | 0.0153 |
Loa Loa (eye worm) | hypothetical protein | 0.0023 | 0.0208 | 0.083 |
Plasmodium falciparum | conserved Plasmodium protein, unknown function | 0.0011 | 0.0055 | 0.0146 |
Mycobacterium tuberculosis | Probable NADH dehydrogenase Ndh | 0.0083 | 0.0965 | 0.2553 |
Trichomonas vaginalis | glutathione reductase, putative | 0.0013 | 0.0073 | 0.0255 |
Brugia malayi | M-phase phosphoprotein, mpp8 | 0.0011 | 0.0055 | 0.022 |
Echinococcus granulosus | replication factor c subunit 1 | 0.001 | 0.0036 | 0.0072 |
Chlamydia trachomatis | dihydrolipoyl dehydrogenase | 0.0013 | 0.0073 | 0.0099 |
Loa Loa (eye worm) | GTP-binding regulatory protein Gs alpha-S chain | 0.0045 | 0.0482 | 0.1922 |
Schistosoma mansoni | histone-lysine n-methyltransferase setb1 | 0.003 | 0.0293 | 0.0585 |
Echinococcus multilocularis | Chromo domain | 0.0011 | 0.0055 | 0.0055 |
Loa Loa (eye worm) | hypothetical protein | 0.0017 | 0.0134 | 0.0533 |
Plasmodium vivax | hypothetical protein, conserved | 0.0011 | 0.0055 | 0.0146 |
Leishmania major | DNA polymerase kappa, putative | 0.0019 | 0.0153 | 0.4101 |
Brugia malayi | ATP dependent DNA ligase C terminal region family protein | 0.001 | 0.0036 | 0.0143 |
Onchocerca volvulus | 0.0011 | 0.0055 | 0.0193 | |
Trichomonas vaginalis | chromodomain-helicase-DNA-binding protein, putative | 0.0011 | 0.0055 | 0.0193 |
Echinococcus multilocularis | histone lysine N methyltransferase SETMAR | 0.003 | 0.0293 | 0.0293 |
Entamoeba histolytica | fatty acid elongase, putative | 0.004 | 0.0415 | 1 |
Echinococcus granulosus | cpg binding protein | 0.003 | 0.0291 | 0.0582 |
Echinococcus multilocularis | histone lysine N methyltransferase MLL3 | 0.0008 | 0.0016 | 0.0016 |
Trypanosoma brucei | unspecified product | 0.0013 | 0.0079 | 0.211 |
Trichomonas vaginalis | DNA polymerase eta, putative | 0.0019 | 0.0153 | 0.0535 |
Loa Loa (eye worm) | hypothetical protein | 0.0017 | 0.0134 | 0.0533 |
Echinococcus multilocularis | chromodomain helicase DNA binding protein 1 | 0.0011 | 0.0055 | 0.0055 |
Trichomonas vaginalis | chromodomain-helicase-DNA-binding protein, putative | 0.0015 | 0.0099 | 0.0344 |
Chlamydia trachomatis | acylglycerophosphoethanolamine acyltransferase | 0.0017 | 0.0134 | 0.0262 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0019 | 0.0153 | 0.4101 |
Entamoeba histolytica | chromodomain-helicase-DNA-binding protein, putative | 0.0011 | 0.0055 | 0.1331 |
Schistosoma mansoni | hypothetical protein | 0.0011 | 0.0055 | 0.011 |
Loa Loa (eye worm) | hypothetical protein | 0.0017 | 0.0134 | 0.0533 |
Trichomonas vaginalis | RNA polymerase II ctd phosphatase, putative | 0.001 | 0.0036 | 0.0125 |
Trichomonas vaginalis | conserved hypothetical protein | 0.001 | 0.0036 | 0.0125 |
Trypanosoma cruzi | DNA polymerase kappa, putative | 0.0019 | 0.0153 | 0.4101 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0027 | 0.0257 | 0.0897 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0039 | 0.0399 | 0.1392 |
Leishmania major | DNA polymerase kappa, putative,DNA polymerase IV, putative | 0.0019 | 0.0153 | 0.4101 |
Echinococcus granulosus | chromodomain helicase DNA binding protein 4 | 0.0013 | 0.0076 | 0.0151 |
Brugia malayi | AMP-binding enzyme family protein | 0.0023 | 0.0208 | 0.083 |
Plasmodium falciparum | thioredoxin reductase | 0.0013 | 0.0073 | 0.0193 |
Mycobacterium tuberculosis | Probable oxidoreductase | 0.0093 | 0.1082 | 0.2864 |
Entamoeba histolytica | hypothetical protein | 0.001 | 0.0036 | 0.0864 |
Trichomonas vaginalis | conserved hypothetical protein | 0.001 | 0.0036 | 0.0125 |
Brugia malayi | hypothetical protein | 0.0017 | 0.0124 | 0.0495 |
Trypanosoma brucei | PAB1-binding protein , putative | 0.0026 | 0.024 | 0.6412 |
Loa Loa (eye worm) | hypothetical protein | 0.0011 | 0.0055 | 0.022 |
Toxoplasma gondii | LsmAD domain-containing protein | 0.0026 | 0.024 | 0.3973 |
Trypanosoma cruzi | dihydrolipoamide dehydrogenase, putative | 0.0013 | 0.0073 | 0.1953 |
Brugia malayi | ImpB/MucB/SamB family protein | 0.0019 | 0.0153 | 0.0611 |
Trypanosoma brucei | DNA polymerase IV, putative | 0.0019 | 0.0153 | 0.4101 |
Echinococcus granulosus | nibrin | 0.001 | 0.0036 | 0.0072 |
Brugia malayi | Pax transcription activation domain interacting protein | 0.001 | 0.0036 | 0.0143 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0011 | 0.0055 | 0.0193 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0039 | 0.0399 | 0.1392 |
Mycobacterium ulcerans | dihydrolipoamide dehydrogenase, LpdB | 0.0013 | 0.0073 | 0.0193 |
Mycobacterium tuberculosis | Fatty-acid-AMP ligase FadD30 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) | 0.0017 | 0.0134 | 0.0354 |
Schistosoma mansoni | chromobox protein-related (chromobox 1) (heterochromatin 1) | 0.0011 | 0.0055 | 0.011 |
Toxoplasma gondii | thioredoxin reductase | 0.0037 | 0.0374 | 0.6197 |
Trypanosoma cruzi | dihydrolipoamide dehydrogenase, putative | 0.0013 | 0.0073 | 0.1953 |
Trichomonas vaginalis | mercuric reductase, putative | 0.0013 | 0.0073 | 0.0255 |
Plasmodium vivax | replication factor C subunit 1, putative | 0.001 | 0.0036 | 0.0095 |
Trichomonas vaginalis | chromodomain helicase DNA binding protein, putative | 0.0018 | 0.0136 | 0.0475 |
Schistosoma mansoni | topbp1 | 0.001 | 0.0036 | 0.0072 |
Brugia malayi | CXXC zinc finger family protein | 0.0028 | 0.0271 | 0.1078 |
Mycobacterium ulcerans | long-chain fatty-acid CoA ligase | 0.0023 | 0.0208 | 0.0551 |
Echinococcus multilocularis | replication factor c subunit 1 | 0.001 | 0.0036 | 0.0036 |
Echinococcus multilocularis | Ataxin 2, N terminal,domain containing protein | 0.0012 | 0.006 | 0.006 |
Giardia lamblia | NADH oxidase lateral transfer candidate | 0.0013 | 0.0073 | 0.3165 |
Loa Loa (eye worm) | hypothetical protein | 0.003 | 0.0293 | 0.1165 |
Loa Loa (eye worm) | hypothetical protein | 0.001 | 0.0036 | 0.0143 |
Toxoplasma gondii | NADPH-glutathione reductase | 0.0013 | 0.0073 | 0.121 |
Wolbachia endosymbiont of Brugia malayi | 3-oxoacyl-ACP synthase | 0.0306 | 0.3778 | 1 |
Mycobacterium ulcerans | 3-oxoacyl-ACP synthase | 0.0306 | 0.3778 | 1 |
Trypanosoma brucei | unspecified product | 0.0013 | 0.0079 | 0.211 |
Mycobacterium tuberculosis | Possible DNA-damage-inducible protein P DinP (DNA polymerase V) (pol IV 2) (DNA nucleotidyltransferase (DNA-directed)) | 0.0019 | 0.0153 | 0.0406 |
Schistosoma mansoni | cpg binding protein | 0.003 | 0.0291 | 0.0582 |
Loa Loa (eye worm) | hypothetical protein | 0.0023 | 0.0208 | 0.083 |
Mycobacterium ulcerans | fatty-acid-CoA ligase | 0.0023 | 0.0208 | 0.0551 |
Brugia malayi | GTP-binding regulatory protein Gs alpha-S chain, putative | 0.0045 | 0.0482 | 0.1922 |
Brugia malayi | hypothetical protein | 0.001 | 0.0036 | 0.0143 |
Echinococcus multilocularis | dna polymerase kappa | 0.0019 | 0.0153 | 0.0153 |
Echinococcus granulosus | dna polymerase eta | 0.0019 | 0.0153 | 0.0307 |
Plasmodium vivax | dihydrolipoyl dehydrogenase, mitochondrial, putative | 0.0013 | 0.0073 | 0.0193 |
Echinococcus multilocularis | chromodomain helicase DNA binding protein 4 | 0.0013 | 0.0076 | 0.0076 |
Echinococcus multilocularis | terminal deoxycytidyl transferase rev1 | 0.0019 | 0.0153 | 0.0153 |
Plasmodium vivax | thioredoxin reductase, putative | 0.0037 | 0.0374 | 0.0991 |
Echinococcus granulosus | geminin | 0.018 | 0.2187 | 0.4374 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0019 | 0.0153 | 0.4101 |
Loa Loa (eye worm) | glutathione reductase | 0.0037 | 0.0374 | 0.1491 |
Entamoeba histolytica | fatty acid elongase, putative | 0.004 | 0.0415 | 1 |
Mycobacterium tuberculosis | Probable reductase | 0.0083 | 0.0965 | 0.2553 |
Loa Loa (eye worm) | histone methyltransferase | 0.001 | 0.0038 | 0.015 |
Trichomonas vaginalis | DNA polymerase IV / kappa, putative | 0.0019 | 0.0153 | 0.0535 |
Trypanosoma brucei | DNA polymerase eta, putative | 0.0019 | 0.0153 | 0.4101 |
Toxoplasma gondii | pyruvate dehydrogenase complex subunit PDH-E3II | 0.0013 | 0.0073 | 0.121 |
Plasmodium falciparum | ataxin-2 like protein, putative | 0.0026 | 0.024 | 0.0635 |
Leishmania major | hypothetical protein, conserved | 0.0026 | 0.024 | 0.6412 |
Brugia malayi | Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain containing protein | 0.0009 | 0.0031 | 0.0122 |
Trypanosoma brucei | dihydrolipoamide dehydrogenase | 0.0013 | 0.0073 | 0.1953 |
Mycobacterium tuberculosis | Probable fatty-acid-CoA ligase FadD2 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) | 0.0023 | 0.0208 | 0.0551 |
Plasmodium vivax | dihydrolipoyl dehydrogenase, apicoplast, putative | 0.0013 | 0.0073 | 0.0193 |
Entamoeba histolytica | fatty acid elongase, putative | 0.004 | 0.0415 | 1 |
Schistosoma mansoni | chromobox protein | 0.0069 | 0.078 | 0.156 |
Giardia lamblia | DINP protein human, muc B family | 0.0019 | 0.0153 | 1 |
Schistosoma mansoni | hypothetical protein | 0.0012 | 0.006 | 0.012 |
Trypanosoma brucei | DNA polymerase IV, putative | 0.0019 | 0.0153 | 0.4101 |
Trichomonas vaginalis | chromobox protein, putative | 0.0041 | 0.0436 | 0.1521 |
Plasmodium vivax | hypothetical protein, conserved | 0.0011 | 0.0055 | 0.0146 |
Plasmodium falciparum | dihydrolipoyl dehydrogenase, mitochondrial | 0.0013 | 0.0073 | 0.0193 |
Onchocerca volvulus | Heterochromatin protein 1 homolog | 0.0041 | 0.0436 | 0.1521 |
Trichomonas vaginalis | conserved hypothetical protein | 0.001 | 0.0036 | 0.0125 |
Echinococcus multilocularis | Chromobox protein 3 | 0.0011 | 0.0055 | 0.0055 |
Echinococcus granulosus | chromobox protein 1 | 0.0069 | 0.078 | 0.156 |
Loa Loa (eye worm) | hypothetical protein | 0.0011 | 0.0055 | 0.022 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0019 | 0.0153 | 0.4101 |
Echinococcus granulosus | Basic leucine zipper bZIP transcription | 0.0035 | 0.0361 | 0.0722 |
Loa Loa (eye worm) | CXXC zinc finger family protein | 0.0028 | 0.0271 | 0.1078 |
Toxoplasma gondii | histone lysine methyltransferase SET/SUV39 | 0.003 | 0.0293 | 0.4844 |
Loa Loa (eye worm) | hypothetical protein | 0.0011 | 0.0055 | 0.022 |
Trichomonas vaginalis | Heterochromatin protein, putative | 0.0011 | 0.0055 | 0.0193 |
Schistosoma mansoni | histone-lysine n-methyltransferase setb1 | 0.003 | 0.0293 | 0.0585 |
Brugia malayi | Type III restriction enzyme, res subunit family protein | 0.0011 | 0.0055 | 0.022 |
Echinococcus granulosus | histone lysine methyltransferase setb | 0.003 | 0.0293 | 0.0585 |
Loa Loa (eye worm) | hypothetical protein | 0.001 | 0.0036 | 0.0143 |
Schistosoma mansoni | hypothetical protein | 0.018 | 0.2187 | 0.4374 |
Schistosoma mansoni | chromodomain helicase DNA binding protein | 0.0013 | 0.0076 | 0.0151 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0019 | 0.0153 | 0.4101 |
Echinococcus granulosus | Ataxin 2 N terminaldomain containing protein | 0.0012 | 0.006 | 0.012 |
Echinococcus multilocularis | geminin | 0.018 | 0.2187 | 0.2187 |
Schistosoma mansoni | chromosome transmission fidelity factor | 0.001 | 0.0036 | 0.0072 |
Wolbachia endosymbiont of Brugia malayi | dihydrolipoamide dehydrogenase E3 component | 0.0013 | 0.0073 | 0.0099 |
Plasmodium falciparum | glutathione reductase | 0.0013 | 0.0073 | 0.0193 |
Trichomonas vaginalis | chromosome transmission fidelity factor, putative | 0.001 | 0.0036 | 0.0125 |
Entamoeba histolytica | hypothetical protein | 0.0035 | 0.0361 | 0.8691 |
Echinococcus granulosus | Chromobox protein 3 | 0.0011 | 0.0055 | 0.011 |
Mycobacterium tuberculosis | Probable soluble pyridine nucleotide transhydrogenase SthA (STH) (NAD(P)(+) transhydrogenase [B-specific]) (nicotinamide nucleot | 0.0013 | 0.0073 | 0.0193 |
Mycobacterium leprae | PROBABLE FATTY-ACID-CoA LIGASE FADD2 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) | 0.0023 | 0.0208 | 0.1926 |
Trypanosoma cruzi | FHA domain containing protein, putative | 0.001 | 0.0036 | 0.0959 |
Schistosoma mansoni | cpg binding protein | 0.0028 | 0.0271 | 0.0541 |
Mycobacterium ulcerans | DNA polymerase IV | 0.0019 | 0.0153 | 0.0406 |
Loa Loa (eye worm) | hypothetical protein | 0.0011 | 0.0055 | 0.022 |
Brugia malayi | AMP-binding enzyme family protein | 0.0023 | 0.0208 | 0.083 |
Mycobacterium leprae | PROBABLE FATTY-ACID-CoA LIGASE FADD7 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) | 0.0023 | 0.0208 | 0.1926 |
Trypanosoma brucei | dihydrolipoyl dehydrogenase | 0.0013 | 0.0073 | 0.1953 |
Leishmania major | acetoin dehydrogenase e3 component-like protein | 0.0013 | 0.0073 | 0.1953 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0045 | 0.0482 | 0.0965 |
Trichomonas vaginalis | chromodomain-helicase-DNA-binding protein, putative | 0.0011 | 0.0055 | 0.0193 |
Entamoeba histolytica | hypothetical protein | 0.0035 | 0.0361 | 0.8691 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0011 | 0.0055 | 0.0193 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0019 | 0.0153 | 0.4101 |
Trichomonas vaginalis | chromodomain helicase DNA binding protein, putative | 0.0018 | 0.0136 | 0.0475 |
Brugia malayi | Heterochromatin protein 1 | 0.0069 | 0.078 | 0.3108 |
Trichomonas vaginalis | hypothetical protein | 0.0011 | 0.0055 | 0.0193 |
Loa Loa (eye worm) | hypothetical protein | 0.0017 | 0.0134 | 0.0533 |
Schistosoma mansoni | chromobox protein-related (chromobox 1) (heterochromatin 1) | 0.0011 | 0.0055 | 0.011 |
Brugia malayi | hypothetical protein | 0.0011 | 0.0055 | 0.022 |
Schistosoma mansoni | histone-lysine n-methyltransferase suv9 | 0.0041 | 0.0434 | 0.0869 |
Leishmania major | DNA polymerase eta, putative | 0.0019 | 0.0153 | 0.4101 |
Mycobacterium ulcerans | 3-oxoacyl-ACP synthase | 0.0306 | 0.3778 | 1 |
Entamoeba histolytica | acyl-CoA synthetase, putative | 0.0023 | 0.0208 | 0.5016 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0011 | 0.0055 | 0.0193 |
Trypanosoma cruzi | DNA polymerase kappa, putative | 0.0019 | 0.0153 | 0.4101 |
Toxoplasma gondii | chromodomain helicase DNA binding protein CHD1/SWI2/SNF2 | 0.0011 | 0.0055 | 0.0915 |
Trichomonas vaginalis | chromobox protein, putative | 0.0069 | 0.078 | 0.272 |
Onchocerca volvulus | 0.0023 | 0.0208 | 0.0726 | |
Schistosoma mansoni | chromobox protein | 0.0011 | 0.0055 | 0.011 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0011 | 0.0055 | 0.0193 |
Entamoeba histolytica | chromodomain-helicase-DNA-binding protein, putative | 0.0011 | 0.0055 | 0.1331 |
Mycobacterium ulcerans | long-chain-fatty-acid--CoA ligase | 0.0023 | 0.0208 | 0.0551 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0019 | 0.0153 | 0.4101 |
Trypanosoma cruzi | PAB1-binding protein , putative | 0.0026 | 0.024 | 0.6412 |
Trichomonas vaginalis | RNA polymerase II ctd phosphatase, putative | 0.001 | 0.0036 | 0.0125 |
Echinococcus granulosus | chromodomain helicase DNA binding protein 1 | 0.0011 | 0.0055 | 0.011 |
Loa Loa (eye worm) | hypothetical protein | 0.0011 | 0.0055 | 0.022 |
Trichomonas vaginalis | chromobox protein, putative | 0.0069 | 0.078 | 0.272 |
Mycobacterium leprae | PROBABLE DNA LIGASE [NAD DEPENDENT] LIGA (POLYDEOXYRIBONUCLEOTIDE SYNTHASE [NAD+]) | 0.001 | 0.0036 | 0.0332 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0011 | 0.0055 | 0.0193 |
Mycobacterium ulcerans | hypothetical protein | 0.0023 | 0.0208 | 0.0551 |
Echinococcus granulosus | terminal deoxycytidyl transferase rev1 | 0.0019 | 0.0153 | 0.0307 |
Trypanosoma cruzi | dihydrolipoamide dehydrogenase, putative | 0.0013 | 0.0073 | 0.1953 |
Brugia malayi | Thioredoxin reductase | 0.0037 | 0.0374 | 0.1491 |
Trichomonas vaginalis | chromobox protein, putative | 0.0011 | 0.0055 | 0.0193 |
Toxoplasma gondii | poly(ADP-ribose) polymerase catalytic domain-containing protein | 0.001 | 0.0036 | 0.0594 |
Loa Loa (eye worm) | hypothetical protein | 0.0019 | 0.0153 | 0.0611 |
Trypanosoma cruzi | trypanothione reductase, putative | 0.0037 | 0.0374 | 1 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0011 | 0.0055 | 0.0193 |
Treponema pallidum | NADH oxidase | 0.0013 | 0.0073 | 1 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0045 | 0.0482 | 0.0965 |
Echinococcus granulosus | mixed lineage leukemia protein mll | 0.0008 | 0.0016 | 0.0032 |
Loa Loa (eye worm) | hypothetical protein | 0.003 | 0.0294 | 0.1172 |
Plasmodium vivax | SET domain protein, putative | 0.003 | 0.0293 | 0.0774 |
Schistosoma mansoni | DNA ligase IV | 0.001 | 0.0036 | 0.0072 |
Brugia malayi | F/Y-rich N-terminus family protein | 0.001 | 0.0036 | 0.0144 |
Echinococcus granulosus | chromobox protein 2 | 0.0011 | 0.0055 | 0.011 |
Toxoplasma gondii | ATPase, AAA family protein | 0.001 | 0.0036 | 0.0594 |
Brugia malayi | chromobox protein homolog 3 | 0.0039 | 0.0399 | 0.159 |
Entamoeba histolytica | hypothetical protein | 0.0035 | 0.0361 | 0.8691 |
Leishmania major | 4-coumarate:coa ligase-like protein | 0.0023 | 0.0208 | 0.5567 |
Mycobacterium tuberculosis | Probable fatty-acid-CoA ligase FadD35 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) | 0.0017 | 0.0122 | 0.0322 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0045 | 0.0482 | 0.0482 |
Trypanosoma cruzi | DNA polymerase eta, putative | 0.0019 | 0.0153 | 0.4101 |
Echinococcus multilocularis | dnaJ subfamily B | 0.0403 | 0.5001 | 0.5001 |
Trypanosoma brucei | unspecified product | 0.0019 | 0.0153 | 0.4101 |
Plasmodium falciparum | heterochromatin protein 1 | 0.0011 | 0.0055 | 0.0146 |
Schistosoma mansoni | terminal deoxycytidyl transferase | 0.0019 | 0.0153 | 0.0307 |
Brugia malayi | AMP-binding enzyme family protein | 0.0023 | 0.0208 | 0.083 |
Mycobacterium leprae | PROBABLE NADH DEHYDROGENASE NDH | 0.0083 | 0.0965 | 0.8916 |
Echinococcus granulosus | dna polymerase kappa | 0.0019 | 0.0153 | 0.0307 |
Brugia malayi | alpha keto acid dehydrogenase complex, E3 component, lipoamide dehydrogenase | 0.0009 | 0.0031 | 0.0122 |
Mycobacterium tuberculosis | Putative ferredoxin reductase | 0.0083 | 0.0965 | 0.2553 |
Leishmania major | trypanothione reductase | 0.0037 | 0.0374 | 1 |
Brugia malayi | CHD4 protein | 0.0013 | 0.0076 | 0.0301 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0019 | 0.0153 | 0.4101 |
Trypanosoma cruzi | trypanothione reductase, putative | 0.0013 | 0.0073 | 0.1953 |
Onchocerca volvulus | 0.0028 | 0.0271 | 0.0944 | |
Plasmodium vivax | acyl-CoA synthetase, putative | 0.0017 | 0.0134 | 0.0354 |
Trypanosoma brucei | trypanothione reductase | 0.0037 | 0.0374 | 1 |
Trichomonas vaginalis | conserved hypothetical protein | 0.001 | 0.0036 | 0.0125 |
Brugia malayi | SET domain containing protein | 0.0013 | 0.0077 | 0.0306 |
Brugia malayi | hypothetical protein | 0.001 | 0.0036 | 0.0143 |
Entamoeba histolytica | hypothetical protein | 0.0011 | 0.0055 | 0.1331 |
Plasmodium falciparum | replication factor C subunit 1, putative | 0.001 | 0.0036 | 0.0095 |
Echinococcus granulosus | chromobox protein 1 | 0.0069 | 0.078 | 0.156 |
Mycobacterium leprae | DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE | 0.0093 | 0.1082 | 1 |
Echinococcus granulosus | dihydrolipoamide dehydrogenase | 0.0013 | 0.0073 | 0.0146 |
Mycobacterium ulcerans | NAD-dependent DNA ligase LigA | 0.001 | 0.0036 | 0.0095 |
Trypanosoma cruzi | dihydrolipoyl dehydrogenase, putative | 0.0013 | 0.0073 | 0.1953 |
Echinococcus multilocularis | thioredoxin glutathione reductase | 0.0037 | 0.038 | 0.038 |
Echinococcus multilocularis | histone lysine methyltransferase setb histone lysine methyltransferase eggless | 0.003 | 0.0293 | 0.0293 |
Echinococcus multilocularis | dihydrolipoamide dehydrogenase | 0.0013 | 0.0073 | 0.0073 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0019 | 0.0153 | 0.4101 |
Schistosoma mansoni | dihydrolipoamide dehydrogenase | 0.0013 | 0.0073 | 0.0146 |
Entamoeba histolytica | hypothetical protein | 0.0011 | 0.0055 | 0.1331 |
Schistosoma mansoni | rab geranylgeranyl transferase alpha subunit | 0.0019 | 0.0153 | 0.0307 |
Plasmodium vivax | beta-ketoacyl-acyl carrier protein synthase III precursor, putative | 0.0306 | 0.3778 | 1 |
Plasmodium falciparum | dihydrolipoyl dehydrogenase, apicoplast | 0.0013 | 0.0073 | 0.0193 |
Mycobacterium tuberculosis | NADPH-dependent mycothiol reductase Mtr | 0.0037 | 0.0374 | 0.0991 |
Brugia malayi | DKFZp564C0469 protein | 0.001 | 0.0036 | 0.0143 |
Brugia malayi | topoisomerase | 0.001 | 0.0036 | 0.0143 |
Echinococcus multilocularis | cpg binding protein | 0.003 | 0.0291 | 0.0291 |
Mycobacterium tuberculosis | Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras | 0.0093 | 0.1082 | 0.2864 |
Loa Loa (eye worm) | helicase | 0.0011 | 0.0055 | 0.022 |
Mycobacterium ulcerans | long-chain-fatty-acid-CoA ligase | 0.0023 | 0.0208 | 0.0551 |
Trypanosoma brucei | DNA polymerase IV, putative | 0.0019 | 0.0153 | 0.4101 |
Trypanosoma cruzi | dihydrolipoyl dehydrogenase, putative | 0.0013 | 0.0073 | 0.1953 |
Plasmodium vivax | glutathione reductase, putative | 0.0037 | 0.0374 | 0.0991 |
Echinococcus granulosus | 5'partial|histone lysine N methyltransferase SETDB2 | 0.0028 | 0.0271 | 0.0542 |
Trichomonas vaginalis | chromodomain-helicase-DNA-binding protein, putative | 0.0018 | 0.0136 | 0.0475 |
Echinococcus multilocularis | histone lysine N methyltransferase MLL3 | 0.001 | 0.0038 | 0.0038 |
Trichomonas vaginalis | chromodomain-helicase-DNA-binding protein, putative | 0.0018 | 0.0136 | 0.0475 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0011 | 0.0055 | 0.0193 |
Chlamydia trachomatis | oxoacyl-ACP synthase III | 0.0306 | 0.3778 | 1 |
Mycobacterium ulcerans | beta-ketoacyl synthase-like protein | 0.0306 | 0.3778 | 1 |
Trypanosoma cruzi | dihydrolipoamide dehydrogenase, putative | 0.0013 | 0.0073 | 0.1953 |
Onchocerca volvulus | 0.0234 | 0.2868 | 1 | |
Mycobacterium ulcerans | fatty-acid-CoA ligase | 0.0017 | 0.0134 | 0.0354 |
Mycobacterium tuberculosis | Probable fatty-acid-CoA ligase FadD5 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) | 0.0017 | 0.0122 | 0.0322 |
Trypanosoma cruzi | dihydrolipoamide dehydrogenase, putative | 0.0013 | 0.0073 | 0.1953 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0019 | 0.0153 | 0.4101 |
Mycobacterium tuberculosis | Conserved hypothetical protein | 0.0019 | 0.0153 | 0.0406 |
Toxoplasma gondii | histone lysine methyltransferase SET1 | 0.0055 | 0.0604 | 1 |
Loa Loa (eye worm) | thioredoxin reductase | 0.0037 | 0.0374 | 0.1491 |
Plasmodium vivax | heterochromatin protein 1, putative | 0.0011 | 0.0055 | 0.0146 |
Trichomonas vaginalis | chromobox protein, putative | 0.0011 | 0.0055 | 0.0193 |
Mycobacterium tuberculosis | Probable fatty-acid-CoA ligase FadD7 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) | 0.0017 | 0.0122 | 0.0322 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0011 | 0.0055 | 0.0193 |
Echinococcus granulosus | histone lysine N methyltransferase MLL3 | 0.001 | 0.0038 | 0.0075 |
Trichomonas vaginalis | replication factor C large subunit, putative | 0.001 | 0.0036 | 0.0125 |
Plasmodium falciparum | thioredoxin reductase | 0.0037 | 0.0374 | 0.0991 |
Brugia malayi | hypothetical protein | 0.0035 | 0.0361 | 0.1438 |
Leishmania major | dihydrolipoamide dehydrogenase, putative | 0.0013 | 0.0073 | 0.1953 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0045 | 0.0482 | 0.0965 |
Plasmodium vivax | ataxin-2 like protein, putative | 0.0026 | 0.024 | 0.0635 |
Mycobacterium tuberculosis | Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB | 0.0083 | 0.0965 | 0.2553 |
Loa Loa (eye worm) | hypothetical protein | 0.0011 | 0.0055 | 0.022 |
Loa Loa (eye worm) | heterochromatin protein 1 | 0.0069 | 0.078 | 0.3108 |
Trypanosoma cruzi | dihydrolipoamide dehydrogenase, putative | 0.0013 | 0.0073 | 0.1953 |
Toxoplasma gondii | 'chromo' (CHRromatin Organization MOdifier) domain-containing protein | 0.0011 | 0.0055 | 0.0915 |
Toxoplasma gondii | 'chromo' (CHRromatin Organization MOdifier) domain-containing protein | 0.0011 | 0.0055 | 0.0915 |
Onchocerca volvulus | Heterochromatin protein 1 homolog | 0.0039 | 0.0399 | 0.1392 |
Echinococcus multilocularis | chromobox protein 2 | 0.0011 | 0.0055 | 0.0055 |
Trichomonas vaginalis | chromodomain helicase DNA binding protein, putative | 0.0018 | 0.0136 | 0.0475 |
Brugia malayi | Protein cec-1. | 0.0011 | 0.0055 | 0.022 |
Brugia malayi | Pre-SET motif family protein | 0.0206 | 0.251 | 1 |
Echinococcus granulosus | histone lysine N methyltransferase MLL3 | 0.0008 | 0.0016 | 0.0032 |
Trichomonas vaginalis | set domain proteins, putative | 0.0234 | 0.2868 | 1 |
Trichomonas vaginalis | chromobox protein, putative | 0.0011 | 0.0055 | 0.0193 |
Schistosoma mansoni | hypothetical protein | 0.018 | 0.2187 | 0.4374 |
Leishmania major | 4-coumarate:coa ligase-like protein | 0.0023 | 0.0208 | 0.5567 |
Brugia malayi | glutathione reductase | 0.0037 | 0.0374 | 0.1491 |
Schistosoma mansoni | hypothetical protein | 0.0035 | 0.0361 | 0.0722 |
Leishmania major | dihydrolipoamide dehydrogenase, putative | 0.0013 | 0.0073 | 0.1953 |
Echinococcus multilocularis | Basic leucine zipper (bZIP) transcription | 0.0035 | 0.0361 | 0.0361 |
Mycobacterium tuberculosis | Probable membrane NADH dehydrogenase NdhA | 0.0083 | 0.0965 | 0.2553 |
Schistosoma mansoni | hypothetical protein | 0.0403 | 0.5001 | 1 |
Plasmodium falciparum | beta-ketoacyl-ACP synthase III | 0.0306 | 0.3778 | 1 |
Schistosoma mansoni | mixed-lineage leukemia protein mll | 0.0061 | 0.0685 | 0.1369 |
Onchocerca volvulus | 0.0041 | 0.0434 | 0.1515 | |
Entamoeba histolytica | Activator 1 140 kDa subunit, putative | 0.001 | 0.0036 | 0.0864 |
Trypanosoma cruzi | PAB1-binding protein , putative | 0.0026 | 0.024 | 0.6412 |
Onchocerca volvulus | 0.001 | 0.0036 | 0.0125 | |
Loa Loa (eye worm) | hypothetical protein | 0.001 | 0.0036 | 0.0143 |
Mycobacterium tuberculosis | 3-oxoacyl-[acyl-carrier-protein] synthase III FabH (beta-ketoacyl-ACP synthase III) (KAS III) | 0.0306 | 0.3778 | 1 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0013 | 0.0079 | 0.211 |
Brugia malayi | Associated with TFs and helicases family protein | 0.0011 | 0.0055 | 0.022 |
Activity type | Activity value | Assay description | Source | Reference |
---|---|---|---|---|
Potency (functional) | 56.2341 uM | PUBCHEM_BIOASSAY: HTS for Inhibitors of HP1-beta Chromodomain Interactions with Methylated Histone Tails. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID488962] | ChEMBL. | No reference |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.