Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Loa Loa (eye worm) | glutamate-gated chloride channel alpha3A subunit | 0.0026 | 0.0218 | 0.0294 |
Loa Loa (eye worm) | hypothetical protein | 0.0056 | 0.0848 | 0.1147 |
Loa Loa (eye worm) | hypothetical protein | 0.0026 | 0.0218 | 0.0294 |
Echinococcus multilocularis | snurportin 1 | 0.0301 | 0.5961 | 0.8064 |
Echinococcus granulosus | histone lysine methyltransferase setb | 0.0035 | 0.0408 | 0.0552 |
Onchocerca volvulus | 0.003 | 0.0308 | 0.0126 | |
Brugia malayi | Hypothetical glycine receptor like protein T20B12.9 in chromosome III | 0.003 | 0.0308 | 0.0417 |
Echinococcus multilocularis | nicotinic acetylcholine receptor subunit alpha 8 | 0.0056 | 0.0848 | 0.1147 |
Brugia malayi | Cation transporter family protein | 0.0138 | 0.2553 | 0.3453 |
Schistosoma mansoni | nAChR subunit | 0.0056 | 0.0848 | 0.1147 |
Brugia malayi | Neuronal acetylcholine receptor protein, alpha-2 chain precursor | 0.0026 | 0.0218 | 0.0294 |
Mycobacterium tuberculosis | Probable reductase | 0.0101 | 0.1789 | 0.1262 |
Loa Loa (eye worm) | hypothetical protein | 0.0056 | 0.0848 | 0.1147 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0077 | 0.1294 | 0.1624 |
Echinococcus multilocularis | thioredoxin glutathione reductase | 0.0045 | 0.0616 | 0.0833 |
Loa Loa (eye worm) | hypothetical protein | 0.0056 | 0.0848 | 0.1147 |
Onchocerca volvulus | 0.0056 | 0.0848 | 0.0878 | |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0098 | 0.1735 | 0.2347 |
Mycobacterium leprae | PROBABLE THYMIDYLATE SYNTHASE THYA (TS) (TSASE) | 0.0369 | 0.7393 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0049 | 0.0696 | 0.0941 |
Echinococcus granulosus | intermediate filament protein | 0.0026 | 0.0229 | 0.0309 |
Loa Loa (eye worm) | hypothetical protein | 0.003 | 0.0308 | 0.0417 |
Plasmodium vivax | thioredoxin reductase, putative | 0.0044 | 0.0603 | 0.0676 |
Loa Loa (eye worm) | hypothetical protein | 0.003 | 0.0308 | 0.0417 |
Mycobacterium tuberculosis | Probable lipase LipE | 0.0077 | 0.1294 | 0.0735 |
Trichomonas vaginalis | set domain proteins, putative | 0.0277 | 0.5472 | 1 |
Trypanosoma cruzi | trypanothione reductase, putative | 0.0044 | 0.0603 | 0.0676 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0098 | 0.1735 | 0.2347 |
Mycobacterium leprae | PROBABLE NADH DEHYDROGENASE NDH | 0.0101 | 0.1789 | 0.0812 |
Loa Loa (eye worm) | hypothetical protein | 0.0026 | 0.0218 | 0.0294 |
Mycobacterium leprae | DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE | 0.0112 | 0.2024 | 0.1198 |
Mycobacterium tuberculosis | Possible conserved lipoprotein LpqK | 0.0077 | 0.1294 | 0.0735 |
Brugia malayi | hypothetical protein | 0.0026 | 0.0218 | 0.0294 |
Echinococcus granulosus | Cys loop ligand gated ion channel subunit | 0.0026 | 0.0218 | 0.0294 |
Trichomonas vaginalis | Importin beta-1 subunit, putative | 0.0023 | 0.0155 | 0.0082 |
Loa Loa (eye worm) | hypothetical protein | 0.0056 | 0.0848 | 0.1147 |
Brugia malayi | Pre-SET motif family protein | 0.0244 | 0.4769 | 0.6451 |
Echinococcus granulosus | 5'partial|histone lysine N methyltransferase SETDB2 | 0.0034 | 0.0381 | 0.0516 |
Loa Loa (eye worm) | beta-LACTamase domain containing family member | 0.0077 | 0.1294 | 0.175 |
Loa Loa (eye worm) | ACC-1 protein | 0.0056 | 0.0848 | 0.1147 |
Brugia malayi | RNA, U transporter 1 | 0.008 | 0.1352 | 0.1829 |
Schistosoma mansoni | nAChR subunit | 0.0056 | 0.0848 | 0.1147 |
Schistosoma mansoni | neurotransmitter gated ion channel | 0.003 | 0.0308 | 0.0417 |
Loa Loa (eye worm) | hypothetical protein | 0.0026 | 0.0218 | 0.0294 |
Brugia malayi | glutathione reductase | 0.0044 | 0.0603 | 0.0816 |
Brugia malayi | nicotinic acetylcholine receptor alpha subunit, putative | 0.0056 | 0.0848 | 0.1147 |
Leishmania major | importin beta-1 subunit, putative | 0.0023 | 0.0155 | 0.0061 |
Echinococcus granulosus | glycine receptor subunit beta | 0.0056 | 0.0848 | 0.1147 |
Entamoeba histolytica | hypothetical protein | 0.003 | 0.0308 | 1 |
Schistosoma mansoni | ran | 0.0021 | 0.0111 | 0.015 |
Brugia malayi | latrophilin 2 splice variant baaae | 0.0033 | 0.0374 | 0.0505 |
Mycobacterium tuberculosis | Probable esterase/lipase LipP | 0.0077 | 0.1294 | 0.0735 |
Brugia malayi | Hypothetical glycine receptor like protein T20B12.9 in chromosome III | 0.0056 | 0.0848 | 0.1147 |
Schistosoma mansoni | histone-lysine n-methyltransferase setb1 | 0.0035 | 0.0408 | 0.0552 |
Loa Loa (eye worm) | nicotinic acetylcholine receptor non-alpha subunit | 0.0056 | 0.0848 | 0.1147 |
Onchocerca volvulus | 0.0056 | 0.0848 | 0.0878 | |
Echinococcus multilocularis | nAChR subunit | 0.003 | 0.0308 | 0.0417 |
Mycobacterium tuberculosis | Putative ferredoxin reductase | 0.0101 | 0.1789 | 0.1262 |
Loa Loa (eye worm) | hypothetical protein | 0.0056 | 0.0848 | 0.1147 |
Echinococcus multilocularis | nicotinic acetylcholine receptor alpha subunit | 0.0056 | 0.0848 | 0.1147 |
Onchocerca volvulus | 0.0138 | 0.2553 | 0.3254 | |
Schistosoma mansoni | Cys-loop ligand gated ion channel subunit | 0.0056 | 0.0848 | 0.1147 |
Loa Loa (eye worm) | hypothetical protein | 0.0056 | 0.0848 | 0.1147 |
Loa Loa (eye worm) | hypothetical protein | 0.0077 | 0.1294 | 0.175 |
Trypanosoma brucei | dihydrofolate reductase-thymidylate synthase | 0.0369 | 0.7393 | 1 |
Trichomonas vaginalis | penicillin-binding protein, putative | 0.0077 | 0.1294 | 0.2206 |
Brugia malayi | excitatory GABA receptor EXP-1A | 0.0056 | 0.0848 | 0.1147 |
Trichomonas vaginalis | esterase, putative | 0.0077 | 0.1294 | 0.2206 |
Loa Loa (eye worm) | intermediate filament protein | 0.0026 | 0.0229 | 0.0309 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0098 | 0.1735 | 0.2347 |
Trypanosoma brucei | trypanothione reductase | 0.0044 | 0.0603 | 0.0676 |
Plasmodium falciparum | importin beta, putative | 0.0028 | 0.0267 | 0.0213 |
Mycobacterium tuberculosis | Probable hydrolase | 0.0077 | 0.1294 | 0.0735 |
Loa Loa (eye worm) | hypothetical protein | 0.0026 | 0.0218 | 0.0294 |
Loa Loa (eye worm) | hypothetical protein | 0.0026 | 0.0229 | 0.0309 |
Echinococcus multilocularis | GTP binding nuclear protein Ran | 0.0021 | 0.0111 | 0.015 |
Loa Loa (eye worm) | hypothetical protein | 0.0035 | 0.0408 | 0.0552 |
Onchocerca volvulus | 0.0077 | 0.1294 | 0.15 | |
Echinococcus granulosus | nicotinic acetylcholine receptor subunit alpha 8 | 0.0056 | 0.0848 | 0.1147 |
Loa Loa (eye worm) | hypothetical protein | 0.0138 | 0.2553 | 0.3453 |
Brugia malayi | hypothetical protein | 0.0026 | 0.0218 | 0.0294 |
Brugia malayi | Neurotransmitter-gated ion-channel transmembrane region family protein | 0.0056 | 0.0848 | 0.1147 |
Echinococcus granulosus | acetylcholine receptor subunit beta 1 | 0.0056 | 0.0848 | 0.1147 |
Schistosoma mansoni | histone-lysine n-methyltransferase setb1 | 0.0035 | 0.0408 | 0.0552 |
Leishmania major | trypanothione reductase | 0.0044 | 0.0603 | 0.0676 |
Echinococcus granulosus | nicotinic acetylcholine receptor alpha subunit | 0.0056 | 0.0848 | 0.1147 |
Schistosoma mansoni | nAChR subunit | 0.0056 | 0.0848 | 0.1147 |
Schistosoma mansoni | nAChR subunit | 0.0026 | 0.0218 | 0.0294 |
Brugia malayi | Neurotransmitter-gated ion-channel ligand binding domain containing protein | 0.0056 | 0.0848 | 0.1147 |
Brugia malayi | Neurotransmitter-gated ion-channel ligand binding domain containing protein | 0.0056 | 0.0848 | 0.1147 |
Brugia malayi | Calcitonin receptor-like protein seb-1 | 0.0049 | 0.0696 | 0.0941 |
Mycobacterium tuberculosis | Probable dehydrogenase | 0.0101 | 0.1789 | 0.1262 |
Echinococcus multilocularis | Cys loop ligand gated ion channel subunit | 0.0026 | 0.0218 | 0.0294 |
Loa Loa (eye worm) | hypothetical protein | 0.003 | 0.0308 | 0.0417 |
Brugia malayi | Neurotransmitter-gated ion-channel ligand binding domain containing protein | 0.0056 | 0.0848 | 0.1147 |
Brugia malayi | Neurotransmitter-gated ion-channel transmembrane region family protein | 0.003 | 0.0308 | 0.0417 |
Loa Loa (eye worm) | glutamate-gated chloride channel alpha3A subunit | 0.0056 | 0.0848 | 0.1147 |
Brugia malayi | beta-lactamase | 0.0077 | 0.1294 | 0.175 |
Loa Loa (eye worm) | ACC-1 protein | 0.0056 | 0.0848 | 0.1147 |
Loa Loa (eye worm) | pre-SET domain-containing protein family protein | 0.0244 | 0.4769 | 0.6451 |
Schistosoma mansoni | nAChR subunit | 0.0056 | 0.0848 | 0.1147 |
Loa Loa (eye worm) | hypothetical protein | 0.003 | 0.0308 | 0.0417 |
Brugia malayi | acetylcholine receptor alpha subunit precursor, putative | 0.0056 | 0.0848 | 0.1147 |
Plasmodium vivax | hypothetical protein, conserved | 0.0077 | 0.1294 | 0.1624 |
Brugia malayi | Neurotransmitter-gated ion-channel transmembrane region family protein | 0.0056 | 0.0848 | 0.1147 |
Schistosoma mansoni | family S12 unassigned peptidase (S12 family) | 0.0077 | 0.1294 | 0.175 |
Schistosoma mansoni | hypothetical protein | 0.0334 | 0.6656 | 0.9003 |
Echinococcus granulosus | nicotinic acetylcholine receptor a11 subunit | 0.0056 | 0.0848 | 0.1147 |
Brugia malayi | GTP-binding regulatory protein Gs alpha-S chain, putative | 0.0098 | 0.1735 | 0.2347 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0098 | 0.1735 | 0.2347 |
Loa Loa (eye worm) | hypothetical protein | 0.0138 | 0.2553 | 0.3453 |
Loa Loa (eye worm) | hypothetical protein | 0.0056 | 0.0848 | 0.1147 |
Echinococcus multilocularis | nicotinic acetylcholine receptor a11 subunit | 0.0056 | 0.0848 | 0.1147 |
Echinococcus multilocularis | neuronal acetylcholine receptor subunit alpha 4 | 0.0056 | 0.0848 | 0.1147 |
Echinococcus granulosus | nAChR subunit | 0.003 | 0.0308 | 0.0417 |
Loa Loa (eye worm) | hypothetical protein | 0.003 | 0.0308 | 0.0417 |
Echinococcus multilocularis | nAChR subunit | 0.0056 | 0.0848 | 0.1147 |
Trichomonas vaginalis | Importin beta-1 subunit, putative | 0.0023 | 0.0155 | 0.0082 |
Brugia malayi | acetylcholine receptor, alpha-type subunit unc-38 precursor | 0.0056 | 0.0848 | 0.1147 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0098 | 0.1735 | 0.2347 |
Loa Loa (eye worm) | hypothetical protein | 0.0026 | 0.0218 | 0.0294 |
Schistosoma mansoni | lamin | 0.0026 | 0.0229 | 0.0309 |
Schistosoma mansoni | nAChR subunit (ShAR1-beta-like) | 0.0138 | 0.2553 | 0.3453 |
Brugia malayi | Neurotransmitter-gated ion-channel ligand binding domain containing protein | 0.0026 | 0.0218 | 0.0294 |
Loa Loa (eye worm) | GTP-binding regulatory protein Gs alpha-S chain | 0.0098 | 0.1735 | 0.2347 |
Echinococcus granulosus | gamma aminobutyric acid receptor subunit | 0.0026 | 0.0218 | 0.0294 |
Brugia malayi | Pre-SET motif family protein | 0.0035 | 0.0408 | 0.0552 |
Echinococcus granulosus | glycine receptor subunit alpha 1 | 0.0056 | 0.0848 | 0.1147 |
Loa Loa (eye worm) | hypothetical protein | 0.0026 | 0.0218 | 0.0294 |
Onchocerca volvulus | 0.0035 | 0.0408 | 0.0266 | |
Plasmodium vivax | glutathione reductase, putative | 0.0044 | 0.0603 | 0.0676 |
Brugia malayi | acetylcholine receptor protein, alpha-like chain, putative | 0.0056 | 0.0848 | 0.1147 |
Toxoplasma gondii | thioredoxin reductase | 0.0044 | 0.0603 | 0.0676 |
Loa Loa (eye worm) | hypothetical protein | 0.0056 | 0.0848 | 0.1147 |
Loa Loa (eye worm) | acetylcholine receptor protein | 0.0026 | 0.0218 | 0.0294 |
Echinococcus multilocularis | glycine receptor subunit beta | 0.0056 | 0.0848 | 0.1147 |
Loa Loa (eye worm) | glutathione reductase | 0.0044 | 0.0603 | 0.0816 |
Brugia malayi | Importin beta-1 subunit | 0.0028 | 0.0267 | 0.0361 |
Loa Loa (eye worm) | hypothetical protein | 0.0056 | 0.0848 | 0.1147 |
Loa Loa (eye worm) | hypothetical protein | 0.0056 | 0.0848 | 0.1147 |
Brugia malayi | hypothetical protein | 0.0026 | 0.0218 | 0.0294 |
Brugia malayi | Neurotransmitter-gated ion-channel ligand binding domain containing protein | 0.0056 | 0.0848 | 0.1147 |
Trichomonas vaginalis | D-aminoacylase, putative | 0.0077 | 0.1294 | 0.2206 |
Brugia malayi | hypothetical protein | 0.0026 | 0.0218 | 0.0294 |
Schistosoma mansoni | hypothetical protein | 0.0301 | 0.5961 | 0.8064 |
Echinococcus multilocularis | histone lysine N methyltransferase SETMAR | 0.0035 | 0.0408 | 0.0552 |
Schistosoma mansoni | importin beta-1 | 0.0028 | 0.0267 | 0.0361 |
Trypanosoma cruzi | importin beta-1 subunit, putative | 0.0023 | 0.0155 | 0.0061 |
Loa Loa (eye worm) | beta-lactamase | 0.0077 | 0.1294 | 0.175 |
Loa Loa (eye worm) | hypothetical protein | 0.003 | 0.0308 | 0.0417 |
Schistosoma mansoni | neurotransmitter gated ion channel | 0.0026 | 0.0218 | 0.0294 |
Echinococcus granulosus | beta LACTamase domain containing family member | 0.0077 | 0.1294 | 0.175 |
Brugia malayi | glutamate-gated chloride channel alpha3A subunit, putative | 0.0026 | 0.0218 | 0.0294 |
Brugia malayi | Cation transporter family protein | 0.0056 | 0.0848 | 0.1147 |
Schistosoma mansoni | Cys-loop ligand gated ion channel subunit | 0.0056 | 0.0848 | 0.1147 |
Schistosoma mansoni | nicotinic acetylcholine receptor alpha | 0.003 | 0.0308 | 0.0417 |
Mycobacterium tuberculosis | Probable thymidylate synthase ThyA (ts) (TSASE) | 0.0369 | 0.7393 | 0.7225 |
Leishmania major | dihydrofolate reductase-thymidylate synthase | 0.0369 | 0.7393 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0056 | 0.0848 | 0.1147 |
Echinococcus multilocularis | nicotinic acetylcholine receptor beta 1 subunit | 0.0056 | 0.0848 | 0.1147 |
Plasmodium falciparum | glutathione reductase | 0.0044 | 0.0603 | 0.0676 |
Echinococcus multilocularis | musashi | 0.0026 | 0.0229 | 0.0309 |
Echinococcus multilocularis | beta LACTamase domain containing family member | 0.0077 | 0.1294 | 0.175 |
Brugia malayi | intermediate filament protein | 0.0026 | 0.0229 | 0.0309 |
Echinococcus multilocularis | acetylcholine receptor subunit beta 1 | 0.0056 | 0.0848 | 0.1147 |
Brugia malayi | Neurotransmitter-gated ion-channel ligand binding domain containing protein | 0.0056 | 0.0848 | 0.1147 |
Loa Loa (eye worm) | ligand-Gated ion Channel family member | 0.0056 | 0.0848 | 0.1147 |
Trypanosoma cruzi | dihydrofolate reductase-thymidylate synthase, putative | 0.0176 | 0.3348 | 0.4445 |
Echinococcus granulosus | GTP binding nuclear protein Ran | 0.0021 | 0.0111 | 0.015 |
Loa Loa (eye worm) | neuronal acetylcholine receptor protein | 0.0026 | 0.0218 | 0.0294 |
Brugia malayi | Corticotropin releasing factor receptor 2 precursor, putative | 0.0049 | 0.0696 | 0.0941 |
Loa Loa (eye worm) | hypothetical protein | 0.0026 | 0.0218 | 0.0294 |
Schistosoma mansoni | nAChR subunit | 0.0026 | 0.0218 | 0.0294 |
Schistosoma mansoni | nAChR subunit | 0.0056 | 0.0848 | 0.1147 |
Loa Loa (eye worm) | hypothetical protein | 0.0056 | 0.0848 | 0.1147 |
Brugia malayi | hypothetical protein | 0.0026 | 0.0218 | 0.0294 |
Trypanosoma brucei | importin beta-1 subunit, putative | 0.0028 | 0.0267 | 0.0213 |
Echinococcus granulosus | glycine receptor subunit alpha 1 | 0.0056 | 0.0848 | 0.1147 |
Giardia lamblia | GTP-binding nuclear protein RAN/TC4 | 0.0021 | 0.0111 | 0.5 |
Onchocerca volvulus | 0.0138 | 0.2553 | 0.3254 | |
Mycobacterium tuberculosis | NAD(P)H quinone reductase LpdA | 0.0112 | 0.2024 | 0.1512 |
Echinococcus multilocularis | lamin | 0.0026 | 0.0229 | 0.0309 |
Mycobacterium tuberculosis | Probable lipase LipD | 0.0077 | 0.1294 | 0.0735 |
Trichomonas vaginalis | D-aminoacylase, putative | 0.0077 | 0.1294 | 0.2206 |
Brugia malayi | Intermediate filament tail domain containing protein | 0.0026 | 0.0229 | 0.0309 |
Brugia malayi | gamma-aminobutyric-acid receptor beta subunit precursor | 0.0056 | 0.0848 | 0.1147 |
Trichomonas vaginalis | importin beta-1, putative | 0.0023 | 0.0155 | 0.0082 |
Loa Loa (eye worm) | hypothetical protein | 0.0077 | 0.1294 | 0.175 |
Echinococcus granulosus | glycine receptor subunit alpha 1 | 0.0056 | 0.0848 | 0.1147 |
Loa Loa (eye worm) | thymidylate synthase | 0.0369 | 0.7393 | 1 |
Echinococcus multilocularis | Cys loop ligand gated ion channel subunit | 0.0056 | 0.0848 | 0.1147 |
Mycobacterium tuberculosis | Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB | 0.0101 | 0.1789 | 0.1262 |
Echinococcus multilocularis | histone lysine methyltransferase setb histone lysine methyltransferase eggless | 0.0035 | 0.0408 | 0.0552 |
Schistosoma mansoni | ran | 0.0021 | 0.0111 | 0.015 |
Brugia malayi | Neurotransmitter-gated ion-channel ligand binding domain containing protein | 0.0056 | 0.0848 | 0.1147 |
Echinococcus granulosus | glycine receptor subunit beta | 0.0056 | 0.0848 | 0.1147 |
Loa Loa (eye worm) | LGC-31 protein | 0.0056 | 0.0848 | 0.1147 |
Loa Loa (eye worm) | hypothetical protein | 0.0077 | 0.1294 | 0.175 |
Trypanosoma brucei | hypothetical protein, conserved | 0.0077 | 0.1294 | 0.1624 |
Schistosoma mansoni | acetylcholine receptor-related | 0.0026 | 0.0218 | 0.0294 |
Loa Loa (eye worm) | intermediate filament tail domain-containing protein | 0.0026 | 0.0229 | 0.0309 |
Echinococcus granulosus | nicotinic acetylcholine receptor beta 1 subunit | 0.0056 | 0.0848 | 0.1147 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0077 | 0.1294 | 0.1624 |
Mycobacterium tuberculosis | Probable conserved lipoprotein | 0.0077 | 0.1294 | 0.0735 |
Loa Loa (eye worm) | hypothetical protein | 0.0026 | 0.0218 | 0.0294 |
Loa Loa (eye worm) | hypothetical protein | 0.0026 | 0.0218 | 0.0294 |
Mycobacterium tuberculosis | Conserved protein | 0.0077 | 0.1294 | 0.0735 |
Loa Loa (eye worm) | hypothetical protein | 0.0056 | 0.0848 | 0.1147 |
Echinococcus granulosus | neuronal acetylcholine receptor subunit alpha 4 | 0.0056 | 0.0848 | 0.1147 |
Onchocerca volvulus | 0.0026 | 0.0229 | 0.0015 | |
Mycobacterium tuberculosis | Conserved protein | 0.0077 | 0.1294 | 0.0735 |
Onchocerca volvulus | 0.0026 | 0.0229 | 0.0015 | |
Brugia malayi | nicotinic acetylcholine receptor beta-1 chain precursor | 0.0056 | 0.0848 | 0.1147 |
Echinococcus multilocularis | geminin | 0.0334 | 0.6656 | 0.9003 |
Loa Loa (eye worm) | hypothetical protein | 0.0028 | 0.0267 | 0.0361 |
Schistosoma mansoni | lamin | 0.0026 | 0.0229 | 0.0309 |
Schistosoma mansoni | hypothetical protein | 0.0334 | 0.6656 | 0.9003 |
Schistosoma mansoni | hypothetical protein | 0.0033 | 0.0374 | 0.0505 |
Mycobacterium tuberculosis | Probable membrane NADH dehydrogenase NdhA | 0.0101 | 0.1789 | 0.1262 |
Schistosoma mansoni | acetylcholine receptor subunit beta | 0.0026 | 0.0218 | 0.0294 |
Loa Loa (eye worm) | excitatory GABA receptor EXP-1A | 0.0056 | 0.0848 | 0.1147 |
Loa Loa (eye worm) | hypothetical protein | 0.003 | 0.0308 | 0.0417 |
Brugia malayi | beta-lactamase family protein | 0.0077 | 0.1294 | 0.175 |
Toxoplasma gondii | HEAT repeat-containing protein | 0.0028 | 0.0267 | 0.0213 |
Loa Loa (eye worm) | acetylcholine receptor alpha subunit | 0.0056 | 0.0848 | 0.1147 |
Schistosoma mansoni | Cys-loop ligand gated ion channel subunit | 0.0056 | 0.0848 | 0.1147 |
Loa Loa (eye worm) | hypothetical protein | 0.0026 | 0.0218 | 0.0294 |
Loa Loa (eye worm) | hypothetical protein | 0.0056 | 0.0848 | 0.1147 |
Loa Loa (eye worm) | hypothetical protein | 0.0056 | 0.0848 | 0.1147 |
Schistosoma mansoni | nAChR subunit (ShAR1-beta2-like) | 0.0056 | 0.0848 | 0.1147 |
Loa Loa (eye worm) | hypothetical protein | 0.0026 | 0.0218 | 0.0294 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0098 | 0.1735 | 0.2347 |
Onchocerca volvulus | 0.0369 | 0.7393 | 1 | |
Echinococcus multilocularis | glycine receptor subunit alpha 1 | 0.0056 | 0.0848 | 0.1147 |
Onchocerca volvulus | 0.0138 | 0.2553 | 0.3254 | |
Loa Loa (eye worm) | hypothetical protein | 0.0056 | 0.0848 | 0.1147 |
Loa Loa (eye worm) | hypothetical protein | 0.0026 | 0.0218 | 0.0294 |
Echinococcus granulosus | thioredoxin glutathione reductase | 0.0045 | 0.0616 | 0.0833 |
Schistosoma mansoni | neurotransmitter gated ion channel | 0.0026 | 0.0218 | 0.0294 |
Toxoplasma gondii | histone lysine methyltransferase SET/SUV39 | 0.0035 | 0.0408 | 0.0408 |
Loa Loa (eye worm) | hypothetical protein | 0.0026 | 0.0218 | 0.0295 |
Entamoeba histolytica | hypothetical protein | 0.0023 | 0.0155 | 0.2239 |
Loa Loa (eye worm) | hypothetical protein | 0.0026 | 0.0218 | 0.0294 |
Plasmodium vivax | SET domain protein, putative | 0.0035 | 0.0408 | 0.0408 |
Echinococcus multilocularis | nicotinic acetylcholine receptor subunit type | 0.0026 | 0.0218 | 0.0294 |
Schistosoma mansoni | histone-lysine n-methyltransferase suv9 | 0.0035 | 0.0408 | 0.0552 |
Schistosoma mansoni | histone-lysine n-methyltransferase setb1 | 0.0035 | 0.0408 | 0.0552 |
Echinococcus granulosus | importin subunit beta 1 | 0.0028 | 0.0267 | 0.0361 |
Echinococcus granulosus | thymidylate synthase | 0.0369 | 0.7393 | 1 |
Trichomonas vaginalis | penicillin-binding protein, putative | 0.0077 | 0.1294 | 0.2206 |
Schistosoma mansoni | nAChR subunit | 0.0056 | 0.0848 | 0.1147 |
Loa Loa (eye worm) | hypothetical protein | 0.0112 | 0.2013 | 0.2723 |
Brugia malayi | Cation transporter family protein | 0.0056 | 0.0848 | 0.1147 |
Brugia malayi | Neurotransmitter-gated ion-channel transmembrane region family protein | 0.003 | 0.0308 | 0.0417 |
Brugia malayi | GTP-binding nuclear protein RAN/TC4 | 0.0021 | 0.0111 | 0.015 |
Mycobacterium tuberculosis | Probable oxidoreductase | 0.0112 | 0.2024 | 0.1512 |
Loa Loa (eye worm) | hypothetical protein | 0.0026 | 0.0218 | 0.0294 |
Brugia malayi | beta-lactamase family protein | 0.0077 | 0.1294 | 0.175 |
Brugia malayi | Thioredoxin reductase | 0.0044 | 0.0603 | 0.0816 |
Echinococcus granulosus | lamin | 0.0026 | 0.0229 | 0.0309 |
Brugia malayi | Neurotransmitter-gated ion-channel ligand binding domain containing protein | 0.0026 | 0.0218 | 0.0294 |
Schistosoma mansoni | Cys-loop ligand gated ion channel subunit | 0.003 | 0.0308 | 0.0417 |
Mycobacterium tuberculosis | Probable NADH dehydrogenase Ndh | 0.0101 | 0.1789 | 0.1262 |
Trichomonas vaginalis | D-aminoacylase, putative | 0.0077 | 0.1294 | 0.2206 |
Brugia malayi | Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative | 0.0077 | 0.1294 | 0.175 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0176 | 0.3348 | 0.6038 |
Echinococcus granulosus | Cys loop ligand gated ion channel subunit | 0.0056 | 0.0848 | 0.1147 |
Leishmania major | hypothetical protein, conserved | 0.0077 | 0.1294 | 0.1624 |
Loa Loa (eye worm) | hypothetical protein | 0.003 | 0.0308 | 0.0417 |
Mycobacterium ulcerans | thymidylate synthase | 0.0369 | 0.7393 | 1 |
Mycobacterium tuberculosis | Probable esterase LipL | 0.0077 | 0.1294 | 0.0735 |
Mycobacterium tuberculosis | Hypothetical protein | 0.0176 | 0.3348 | 0.2921 |
Trypanosoma cruzi | dihydrofolate reductase-thymidylate synthase | 0.0369 | 0.7393 | 1 |
Toxoplasma gondii | bifunctional dihydrofolate reductase-thymidylate synthase | 0.0369 | 0.7393 | 1 |
Schistosoma mansoni | intermediate filament proteins | 0.0026 | 0.0229 | 0.0309 |
Brugia malayi | thymidylate synthase | 0.0369 | 0.7393 | 1 |
Echinococcus granulosus | lamin dm0 | 0.0026 | 0.0229 | 0.0309 |
Loa Loa (eye worm) | hypothetical protein | 0.0077 | 0.1294 | 0.175 |
Echinococcus multilocularis | glycine receptor subunit alpha 1 | 0.0056 | 0.0848 | 0.1147 |
Echinococcus granulosus | geminin | 0.0334 | 0.6656 | 0.9003 |
Onchocerca volvulus | 0.003 | 0.0308 | 0.0126 | |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0098 | 0.1735 | 0.2347 |
Onchocerca volvulus | 0.0056 | 0.0848 | 0.0878 | |
Mycobacterium tuberculosis | Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras | 0.0112 | 0.2024 | 0.1512 |
Schistosoma mansoni | bifunctional dihydrofolate reductase-thymidylate synthase | 0.0369 | 0.7393 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0026 | 0.0218 | 0.0294 |
Echinococcus granulosus | nAChR subunit | 0.0056 | 0.0848 | 0.1147 |
Loa Loa (eye worm) | nicotinic acetylcholine receptor alpha subunit | 0.0056 | 0.0848 | 0.1147 |
Loa Loa (eye worm) | thioredoxin reductase | 0.0044 | 0.0603 | 0.0816 |
Onchocerca volvulus | 0.0077 | 0.1294 | 0.15 | |
Brugia malayi | hypothetical protein | 0.0176 | 0.3348 | 0.4529 |
Brugia malayi | Neurotransmitter-gated ion-channel transmembrane region family protein | 0.0056 | 0.0848 | 0.1147 |
Echinococcus multilocularis | glycine receptor subunit alpha 1 | 0.0056 | 0.0848 | 0.1147 |
Onchocerca volvulus | 0.0277 | 0.5472 | 0.7323 | |
Loa Loa (eye worm) | hypothetical protein | 0.0033 | 0.0374 | 0.0505 |
Loa Loa (eye worm) | hypothetical protein | 0.0077 | 0.1294 | 0.175 |
Schistosoma mansoni | nAChR subunit (ShAR1-alpha-like) | 0.0138 | 0.2553 | 0.3453 |
Loa Loa (eye worm) | nucleolar RNA-associated protein alpha | 0.0301 | 0.5961 | 0.8064 |
Echinococcus multilocularis | gamma aminobutyric acid receptor subunit | 0.0026 | 0.0218 | 0.0294 |
Loa Loa (eye worm) | GTP-binding nuclear protein RAN/TC4 | 0.0021 | 0.0111 | 0.015 |
Trypanosoma brucei | importin beta-1 subunit, putative | 0.0028 | 0.0267 | 0.0213 |
Brugia malayi | glutamate-gated chloride channel alpha3A subunit, putative | 0.003 | 0.0308 | 0.0417 |
Plasmodium falciparum | bifunctional dihydrofolate reductase-thymidylate synthase | 0.0369 | 0.7393 | 1 |
Echinococcus multilocularis | glycine receptor subunit beta | 0.0056 | 0.0848 | 0.1147 |
Echinococcus multilocularis | lamin dm0 | 0.0026 | 0.0229 | 0.0309 |
Brugia malayi | Neurotransmitter-gated ion-channel ligand binding domain containing protein | 0.0026 | 0.0218 | 0.0294 |
Schistosoma mansoni | nAChR subunit | 0.0056 | 0.0848 | 0.1147 |
Onchocerca volvulus | 0.0077 | 0.1294 | 0.15 | |
Echinococcus multilocularis | importin subunit beta 1 | 0.0028 | 0.0267 | 0.0361 |
Toxoplasma gondii | ABC1 family protein | 0.0077 | 0.1294 | 0.1624 |
Loa Loa (eye worm) | hypothetical protein | 0.0077 | 0.1294 | 0.175 |
Brugia malayi | Acetylcholine receptor protein, alpha-like chain 1 precursor | 0.0026 | 0.0218 | 0.0294 |
Mycobacterium tuberculosis | Conserved protein | 0.0077 | 0.1294 | 0.0735 |
Loa Loa (eye worm) | pigment dispersing factor receptor c | 0.0049 | 0.0696 | 0.0941 |
Plasmodium falciparum | thioredoxin reductase | 0.0044 | 0.0603 | 0.0676 |
Echinococcus multilocularis | thymidylate synthase | 0.0369 | 0.7393 | 1 |
Plasmodium vivax | importin-beta 2, putative | 0.0028 | 0.0267 | 0.0213 |
Plasmodium vivax | bifunctional dihydrofolate reductase-thymidylate synthase, putative | 0.0369 | 0.7393 | 1 |
Echinococcus granulosus | snurportin 1 | 0.0301 | 0.5961 | 0.8064 |
Loa Loa (eye worm) | hypothetical protein | 0.0056 | 0.0848 | 0.1147 |
Echinococcus granulosus | nicotinic acetylcholine receptor subunit type | 0.0056 | 0.0848 | 0.1147 |
Loa Loa (eye worm) | GABA receptor subunit | 0.003 | 0.0308 | 0.0417 |
Schistosoma mansoni | family S12 unassigned peptidase (S12 family) | 0.0077 | 0.1294 | 0.175 |
Onchocerca volvulus | Putative nachr subunit | 0.0056 | 0.0848 | 0.0878 |
Activity type | Activity value | Assay description | Source | Reference |
---|---|---|---|---|
Inhibition (functional) | 0 % | Compound was evaluated for its agonist activity against mGluR6 in Chinese hamster ovary (CHO) cells; Inactive | ChEMBL. | 9873559 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.
1 literature reference was collected for this gene.