Detailed information for compound 1340442

Basic information

Technical information
  • TDR Targets ID: 1340442
  • Name: 4-methyl-N-[3-([1,3]oxazolo[4,5-b]pyridin-2-y l)phenyl]benzamide
  • MW: 329.352 | Formula: C20H15N3O2
  • H donors: 1 H acceptors: 3 LogP: 3.89 Rotable bonds: 4
    Rule of 5 violations (Lipinski): 1
  • SMILES: Cc1ccc(cc1)C(=O)Nc1cccc(c1)c1nc2c(o1)cccn2
  • InChi: 1S/C20H15N3O2/c1-13-7-9-14(10-8-13)19(24)22-16-5-2-4-15(12-16)20-23-18-17(25-20)6-3-11-21-18/h2-12H,1H3,(H,22,24)
  • InChiKey: SIIASTIMVKRMRA-UHFFFAOYSA-N  


Substructure search Similarity search

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Synonyms

  • 4-methyl-N-(3-oxazolo[4,5-b]pyridin-2-ylphenyl)benzamide
  • 4-methyl-N-[3-(2-oxazolo[4,5-b]pyridinyl)phenyl]benzamide
  • STK184148
  • Oprea1_786015
  • 4-Methyl-N-(3-oxazolo[4,5-b]pyridin-2-yl-phenyl)-benzamide
  • MLS001012237
  • SMR000425267
  • ZINC01240963

Targets

Known targets for this compound

Species Target name Source Bibliographic reference
Photinus pyralis Luciferin 4-monooxygenase Starlite/ChEMBL No references
Homo sapiens TAR DNA binding protein Starlite/ChEMBL No references
Homo sapiens EYA transcriptional coactivator and phosphatase 2 Starlite/ChEMBL No references
Homo sapiens Werner syndrome, RecQ helicase-like Starlite/ChEMBL No references

Predicted pathogen targets for this compound

By orthology
Species Potential target Known druggable target/s Ortholog Group
Loa Loa (eye worm) ATP-dependent DNA helicase Get druggable targets OG5_126644 All targets in OG5_126644
Entamoeba histolytica recQ family DNA helicase Get druggable targets OG5_126644 All targets in OG5_126644
Trichomonas vaginalis DNA helicase recq1, putative Get druggable targets OG5_126644 All targets in OG5_126644
Brugia malayi ATP-dependent DNA helicase, RecQ family protein Get druggable targets OG5_126644 All targets in OG5_126644
Plasmodium falciparum ATP-dependent DNA helicase Q1 Get druggable targets OG5_126644 All targets in OG5_126644
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_126609 All targets in OG5_126609
Leishmania major ATP-dependent DEAD/H DNA helicase recQ, putative Get druggable targets OG5_126644 All targets in OG5_126644
Plasmodium knowlesi acyl-CoA synthetase, putative Get druggable targets OG5_126609 All targets in OG5_126609
Leishmania major 4-coumarate:coa ligase-like protein Get druggable targets OG5_126609 All targets in OG5_126609
Loa Loa (eye worm) RNA recognition domain-containing protein domain-containing protein Get druggable targets OG5_132461 All targets in OG5_132461
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD35 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) Get druggable targets OG5_126609 All targets in OG5_126609
Mycobacterium ulcerans long-chain fatty-acid CoA ligase Get druggable targets OG5_126609 All targets in OG5_126609
Plasmodium vivax ADP-dependent DNA helicase RecQ, putative Get druggable targets OG5_126644 All targets in OG5_126644
Plasmodium berghei ADP-dependent DNA helicase RecQ, putative Get druggable targets OG5_126644 All targets in OG5_126644
Leishmania major 4-coumarate:coa ligase-like protein Get druggable targets OG5_126609 All targets in OG5_126609
Brugia malayi RNA binding protein Get druggable targets OG5_132461 All targets in OG5_132461
Brugia malayi TAR-binding protein Get druggable targets OG5_132461 All targets in OG5_132461
Leishmania donovani 4-coumarate:coa ligase-like protein Get druggable targets OG5_126609 All targets in OG5_126609
Plasmodium knowlesi ATP-dependent DNA helicase Q1, putative Get druggable targets OG5_126644 All targets in OG5_126644
Mycobacterium ulcerans hypothetical protein Get druggable targets OG5_126609 All targets in OG5_126609
Trypanosoma brucei ATP-dependent DEAD/H DNA helicase recQ, putative Get druggable targets OG5_126644 All targets in OG5_126644
Leishmania infantum 4-coumarate:coa ligase-like protein Get druggable targets OG5_126609 All targets in OG5_126609
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_126609 All targets in OG5_126609
Loa Loa (eye worm) RecQ helicase Get druggable targets OG5_126644 All targets in OG5_126644
Plasmodium yoelii ATP-dependent DNA helicase-related Get druggable targets OG5_126644 All targets in OG5_126644
Mycobacterium ulcerans acyl-CoA synthetase Get druggable targets OG5_126609 All targets in OG5_126609
Plasmodium yoelii peroxisomal-coenzyme a synthetase Get druggable targets OG5_126609 All targets in OG5_126609
Mycobacterium ulcerans acyl-CoA synthetase Get druggable targets OG5_126609 All targets in OG5_126609
Schistosoma japonicum TAR DNA-binding protein 43, putative Get druggable targets OG5_132461 All targets in OG5_132461
Treponema pallidum ATP-dependent DNA helicase Get druggable targets OG5_126644 All targets in OG5_126644
Neospora caninum hypothetical protein Get druggable targets OG5_126644 All targets in OG5_126644
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_126644 All targets in OG5_126644
Schistosoma mansoni DNA helicase recq1 Get druggable targets OG5_126644 All targets in OG5_126644
Chlamydia trachomatis acylglycerophosphoethanolamine acyltransferase Get druggable targets OG5_126609 All targets in OG5_126609
Plasmodium vivax acyl-CoA synthetase, putative Get druggable targets OG5_126609 All targets in OG5_126609
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_126644 All targets in OG5_126644
Leishmania mexicana 4-coumarate:coa ligase-like protein Get druggable targets OG5_126609 All targets in OG5_126609
Mycobacterium ulcerans fatty-acid-CoA ligase Get druggable targets OG5_126609 All targets in OG5_126609
Plasmodium berghei ATP-dependent DNA helicase Q1, putative Get druggable targets OG5_126644 All targets in OG5_126644
Cryptosporidium parvum RecQ bloom helicase (RNA helicase+hrdc) Get druggable targets OG5_126644 All targets in OG5_126644
Brugia malayi RNA recognition motif domain containing protein Get druggable targets OG5_132461 All targets in OG5_132461
Echinococcus granulosus bloom syndrome protein Get druggable targets OG5_126644 All targets in OG5_126644
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_129664 All targets in OG5_129664
Plasmodium berghei acyl-CoA synthetase, putative Get druggable targets OG5_126609 All targets in OG5_126609
Leishmania mexicana 4-coumarate:coa ligase-like protein Get druggable targets OG5_126609 All targets in OG5_126609
Babesia bovis ATP-dependent DNA helicase, RecQ family protein Get druggable targets OG5_126644 All targets in OG5_126644
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_126644 All targets in OG5_126644
Candida albicans DNA helicase Get druggable targets OG5_126644 All targets in OG5_126644
Schistosoma japonicum TAR DNA-binding protein 43, putative Get druggable targets OG5_132461 All targets in OG5_132461
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein Get druggable targets OG5_126644 All targets in OG5_126644
Mycobacterium ulcerans long-chain-fatty-acid-CoA ligase Get druggable targets OG5_126609 All targets in OG5_126609
Echinococcus multilocularis bloom syndrome protein Get druggable targets OG5_126644 All targets in OG5_126644
Brugia malayi hypothetical protein Get druggable targets OG5_129664 All targets in OG5_129664
Mycobacterium tuberculosis Fatty-acid-AMP ligase FadD30 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) Get druggable targets OG5_126609 All targets in OG5_126609
Mycobacterium tuberculosis Probable chain -fatty-acid-CoA ligase FadD13 (fatty-acyl-CoA synthetase) Get druggable targets OG5_126609 All targets in OG5_126609
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_129664 All targets in OG5_129664
Leishmania infantum ATP-dependent DEAD/H DNA helicase recQ, putative Get druggable targets OG5_126644 All targets in OG5_126644
Echinococcus multilocularis ATP dependent DNA helicase Q1 Get druggable targets OG5_126644 All targets in OG5_126644
Entamoeba histolytica acyl-CoA synthetase, putative Get druggable targets OG5_126609 All targets in OG5_126609
Theileria parva hypothetical protein Get druggable targets OG5_126644 All targets in OG5_126644
Leishmania mexicana 4-coumarate:coa ligase-like protein Get druggable targets OG5_126609 All targets in OG5_126609
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_126609 All targets in OG5_126609
Schistosoma mansoni DNA helicase recq5 Get druggable targets OG5_126644 All targets in OG5_126644
Schistosoma mansoni tar DNA-binding protein Get druggable targets OG5_132461 All targets in OG5_132461
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD2 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) Get druggable targets OG5_126609 All targets in OG5_126609
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_126609 All targets in OG5_126609
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_126609 All targets in OG5_126609
Entamoeba histolytica acyl-CoA synthetase, putative Get druggable targets OG5_126609 All targets in OG5_126609
Plasmodium yoelii ATP-dependent DNA helicase recQ-related Get druggable targets OG5_126644 All targets in OG5_126644
Onchocerca volvulus Get druggable targets OG5_126609 All targets in OG5_126609
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD7 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) Get druggable targets OG5_126609 All targets in OG5_126609
Leishmania donovani 4-coumarate:coa ligase-like protein Get druggable targets OG5_126609 All targets in OG5_126609
Schistosoma mansoni tar DNA-binding protein Get druggable targets OG5_132461 All targets in OG5_132461
Schistosoma mansoni tar DNA-binding protein Get druggable targets OG5_132461 All targets in OG5_132461
Theileria parva DNA helicase, putative Get druggable targets OG5_126644 All targets in OG5_126644
Schistosoma japonicum ko:K01104 protein-tyrosine phosphatase [EC3.1.3.48], putative Get druggable targets OG5_129664 All targets in OG5_129664
Leishmania mexicana ATP-dependent DEAD/H DNA helicase recQ, putative Get druggable targets OG5_126644 All targets in OG5_126644
Leishmania infantum 4-coumarate:coa ligase-like protein Get druggable targets OG5_126609 All targets in OG5_126609
Echinococcus granulosus ATP dependent DNA helicase Q5 Get druggable targets OG5_126644 All targets in OG5_126644
Schistosoma mansoni eyes absent homolog Get druggable targets OG5_129664 All targets in OG5_129664
Trichomonas vaginalis DNA helicase recq, putative Get druggable targets OG5_126644 All targets in OG5_126644
Babesia bovis ATP-dependent DNA helicase, RecQ family protein Get druggable targets OG5_126644 All targets in OG5_126644
Echinococcus granulosus tar DNA binding protein Get druggable targets OG5_132461 All targets in OG5_132461
Leishmania infantum 4-coumarate:coa ligase-like protein Get druggable targets OG5_126609 All targets in OG5_126609
Giardia lamblia Sgs1 DNA helicase, putative Get druggable targets OG5_126644 All targets in OG5_126644
Schistosoma mansoni tar DNA-binding protein Get druggable targets OG5_132461 All targets in OG5_132461
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein Get druggable targets OG5_126644 All targets in OG5_126644
Schistosoma mansoni blooms syndrome DNA helicase Get druggable targets OG5_126644 All targets in OG5_126644
Plasmodium falciparum ADP-dependent DNA helicase RecQ Get druggable targets OG5_126644 All targets in OG5_126644
Plasmodium knowlesi ADP-dependent DNA helicase RecQ, putative Get druggable targets OG5_126644 All targets in OG5_126644
Leishmania braziliensis ATP-dependent DEAD/H DNA helicase recQ, putative Get druggable targets OG5_126644 All targets in OG5_126644
Brugia malayi AMP-binding enzyme family protein Get druggable targets OG5_126609 All targets in OG5_126609
Entamoeba histolytica recQ family helicase, putative Get druggable targets OG5_126644 All targets in OG5_126644
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD5 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) Get druggable targets OG5_126609 All targets in OG5_126609
Schistosoma japonicum Bloom syndrome protein homolog, putative Get druggable targets OG5_126644 All targets in OG5_126644
Echinococcus multilocularis ATP dependent DNA helicase Q5 Get druggable targets OG5_126644 All targets in OG5_126644
Echinococcus multilocularis tar DNA binding protein Get druggable targets OG5_132461 All targets in OG5_132461
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_126609 All targets in OG5_126609
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_126609 All targets in OG5_126609
Neospora caninum hypothetical protein Get druggable targets OG5_126644 All targets in OG5_126644
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD3 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) Get druggable targets OG5_126609 All targets in OG5_126609
Brugia malayi ATP-dependent DNA helicase, RecQ family protein Get druggable targets OG5_126644 All targets in OG5_126644
Candida albicans DNA helicase Get druggable targets OG5_126644 All targets in OG5_126644
Cryptosporidium hominis DEAD/DEAH box helicase Get druggable targets OG5_126644 All targets in OG5_126644
Leishmania infantum 4-coumarate:coa ligase-like protein Get druggable targets OG5_126609 All targets in OG5_126609
Trypanosoma cruzi ATP-dependent DEAD/H DNA helicase recQ, putative Get druggable targets OG5_126644 All targets in OG5_126644
Brugia malayi AMP-binding enzyme family protein Get druggable targets OG5_126609 All targets in OG5_126609
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD7 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) Get druggable targets OG5_126609 All targets in OG5_126609
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD2 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) Get druggable targets OG5_126609 All targets in OG5_126609
Loa Loa (eye worm) RNA binding protein Get druggable targets OG5_132461 All targets in OG5_132461
Schistosoma japonicum ko:K03654 ATP-dependent DNA helicase RecQ, putative Get druggable targets OG5_126644 All targets in OG5_126644
Plasmodium falciparum acyl-CoA synthetase Get druggable targets OG5_126609 All targets in OG5_126609
Mycobacterium ulcerans acyl-CoA synthetase Get druggable targets OG5_126609 All targets in OG5_126609
Schistosoma mansoni tar DNA-binding protein Get druggable targets OG5_132461 All targets in OG5_132461
Leishmania major 4-coumarate:coa ligase-like protein Get druggable targets OG5_126609 All targets in OG5_126609
Brugia malayi Bloom's syndrome protein homolog Get druggable targets OG5_126644 All targets in OG5_126644
Leishmania braziliensis 4-coumarate:coa ligase-like protein Get druggable targets OG5_126609 All targets in OG5_126609
Trichomonas vaginalis DNA helicase recq, putative Get druggable targets OG5_126644 All targets in OG5_126644
Echinococcus granulosus ATP dependent DNA helicase Q1 Get druggable targets OG5_126644 All targets in OG5_126644
Brugia malayi AMP-binding enzyme family protein Get druggable targets OG5_126609 All targets in OG5_126609
Leishmania donovani ATP-dependent DEAD/H DNA helicase recQ, putative Get druggable targets OG5_126644 All targets in OG5_126644
Trypanosoma cruzi ATP-dependent DEAD/H DNA helicase recQ, putative Get druggable targets OG5_126644 All targets in OG5_126644
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein Get druggable targets OG5_126644 All targets in OG5_126644
Trypanosoma cruzi ATP-dependent DEAD/H DNA helicase recQ, putative Get druggable targets OG5_126644 All targets in OG5_126644
Entamoeba histolytica acyl-coA synthetase, putative Get druggable targets OG5_126609 All targets in OG5_126609
Mycobacterium ulcerans fatty-acid-CoA ligase Get druggable targets OG5_126609 All targets in OG5_126609
Loa Loa (eye worm) TAR-binding protein Get druggable targets OG5_132461 All targets in OG5_132461
Mycobacterium ulcerans long-chain-fatty-acid--CoA ligase Get druggable targets OG5_126609 All targets in OG5_126609
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_126609 All targets in OG5_126609
Trypanosoma brucei gambiense ATP-dependent DEAD/H DNA helicase recQ, putative Get druggable targets OG5_126644 All targets in OG5_126644
By sequence similarity to non orthologous known druggable targets
Species Potential target Known druggable target Length Alignment span Identity
Mycobacterium ulcerans fatty-acid-CoA ligase FadD11 Luciferin 4-monooxygenase   550 aa 498 aa 23.5 %
Mycobacterium tuberculosis Probable fatty-acid-AMP ligase FadD21 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) Luciferin 4-monooxygenase   550 aa 586 aa 24.4 %
Mycobacterium tuberculosis Fatty-acid-AMP ligase FadD28 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) Luciferin 4-monooxygenase   550 aa 504 aa 22.6 %
Echinococcus granulosus long chain fatty acid coenzyme A ligase 5 Luciferin 4-monooxygenase   550 aa 458 aa 25.8 %
Dictyostelium discoideum hypothetical protein Luciferin 4-monooxygenase   550 aa 463 aa 23.5 %
Dictyostelium discoideum fatty acyl-CoA synthetase Luciferin 4-monooxygenase   550 aa 501 aa 24.4 %
Dictyostelium discoideum hypothetical protein Luciferin 4-monooxygenase   550 aa 535 aa 21.7 %
Mycobacterium tuberculosis Bifunctional enzyme MbtA: salicyl-AMP ligase (SAL-AMP ligase) + salicyl-S-ArCP synthetase Luciferin 4-monooxygenase   550 aa 536 aa 24.4 %
Babesia bovis long-chain acyl-CoA synthetase, putative Luciferin 4-monooxygenase   550 aa 445 aa 21.8 %
Trichomonas vaginalis AMP dependent CoA ligase, putative Luciferin 4-monooxygenase   550 aa 492 aa 23.6 %
Dictyostelium discoideum hypothetical protein Luciferin 4-monooxygenase   550 aa 541 aa 21.4 %
Dictyostelium discoideum hypothetical protein Luciferin 4-monooxygenase   550 aa 542 aa 22.1 %
Candida albicans similar to S. cerevisiae ACS2 (YLR153C) acetyl-CoA synthetase Luciferin 4-monooxygenase   550 aa 543 aa 24.5 %
Mycobacterium leprae FATTY-ACID-CoA LIGASE FADD26 (FATTY-ACID-COA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) Luciferin 4-monooxygenase   550 aa 533 aa 22.7 %
Dictyostelium discoideum hypothetical protein Luciferin 4-monooxygenase   550 aa 499 aa 19.2 %
Mycobacterium ulcerans acyl-CoA synthetase Luciferin 4-monooxygenase   550 aa 530 aa 23.8 %
Trichomonas vaginalis antibiotic synthetase, putative Luciferin 4-monooxygenase   550 aa 577 aa 22.2 %
Mycobacterium tuberculosis Probable acyl-CoA ligase FadD31 (acyl-CoA synthetase) (acyl-CoA synthase) Luciferin 4-monooxygenase   550 aa 592 aa 20.4 %
Entamoeba histolytica long-chain-fatty-acid--CoA ligase, putative Luciferin 4-monooxygenase   550 aa 476 aa 20.8 %
Trichomonas vaginalis long-chain-fatty-acid CoA ligase, putative Luciferin 4-monooxygenase   550 aa 490 aa 23.3 %
Schistosoma japonicum ko:K08745 solute carrier family 27 (fatty acid transporter), member 1, putative Luciferin 4-monooxygenase   550 aa 501 aa 24.6 %
Entamoeba histolytica long-chain-fatty-acid--CoA ligase, putative Luciferin 4-monooxygenase   550 aa 480 aa 21.5 %
Cryptosporidium hominis acetyl-CoenzymeA synthetase (acetate--coa ligase) (acyl-activating enzyme) Luciferin 4-monooxygenase   550 aa 549 aa 22.6 %
Trypanosoma cruzi fatty acyl CoA synthetase, putative Luciferin 4-monooxygenase   550 aa 482 aa 24.7 %
Mycobacterium ulcerans long-chain-fatty-acid--CoA ligase Luciferin 4-monooxygenase   550 aa 509 aa 21.8 %
Mycobacterium ulcerans acyl-CoA synthetase Luciferin 4-monooxygenase   550 aa 601 aa 22.5 %
Onchocerca volvulus Lysine-specific histone demethylase 1A homolog Luciferin 4-monooxygenase   550 aa 550 aa 22.5 %
Leishmania braziliensis long-chain-fatty-acid-CoA ligase, putative Luciferin 4-monooxygenase   550 aa 504 aa 25.6 %
Trichomonas vaginalis AMP dependent ligase/synthetase, putative Luciferin 4-monooxygenase   550 aa 554 aa 24.4 %
Dictyostelium discoideum hypothetical protein Luciferin 4-monooxygenase   550 aa 522 aa 19.9 %
Leishmania major long chain fatty Acyl CoA synthetase, putative Luciferin 4-monooxygenase   550 aa 482 aa 23.2 %
Cryptosporidium parvum putative long chain fatty acyl CoA synthetase having a signal peptide Luciferin 4-monooxygenase   550 aa 472 aa 24.8 %
Schistosoma mansoni FAA1 Long-chain-fatty-acid--CoA ligase 1 Luciferin 4-monooxygenase   550 aa 494 aa 26.3 %
Mycobacterium ulcerans acyl-CoA synthetase Luciferin 4-monooxygenase   550 aa 582 aa 22.3 %
Trypanosoma brucei fatty acyl CoA synthetase 3 Luciferin 4-monooxygenase   550 aa 491 aa 23.6 %
Dictyostelium discoideum AMP-dependent synthetase and ligase domain-containing protein Luciferin 4-monooxygenase   550 aa 517 aa 24.8 %
Mycobacterium ulcerans putative fatty-acid--CoA ligase Luciferin 4-monooxygenase   550 aa 576 aa 20.8 %
Dictyostelium discoideum hypothetical protein Luciferin 4-monooxygenase   550 aa 542 aa 18.3 %
Mycobacterium leprae Probable fatty-acid-CoA synthetase FadD22 (fatty-acid-CoA ligase) (fatty-acid-CoA synthase) Luciferin 4-monooxygenase   550 aa 493 aa 20.7 %
Trichomonas vaginalis antibiotic synthetase, putative Luciferin 4-monooxygenase   550 aa 581 aa 21.2 %
Candida albicans similar to S. cerevisiae FAA4 (YMR246W) long-chain fatty acid--CoA synthetase Luciferin 4-monooxygenase   550 aa 478 aa 23.4 %
Onchocerca volvulus Luciferin 4-monooxygenase   550 aa 502 aa 24.9 %
Mycobacterium ulcerans long-chain-fatty-acid-CoA ligase, FadD11 Luciferin 4-monooxygenase   550 aa 492 aa 24.6 %
Candida albicans similar to S. cerevisiae FAT1 (YBR041W) fatty acid transporter and very long-chain fatty acyl-CoA synthetase Luciferin 4-monooxygenase   550 aa 496 aa 24.2 %
Mycobacterium tuberculosis Probable fatty-acid-AMP ligase FadD25 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) Luciferin 4-monooxygenase   550 aa 475 aa 21.1 %
Mycobacterium ulcerans long-chain-fatty-acid-CoA ligase FadD15 Luciferin 4-monooxygenase   550 aa 484 aa 26.0 %
Dictyostelium discoideum hypothetical protein Luciferin 4-monooxygenase   550 aa 576 aa 19.8 %
Trypanosoma brucei gambiense fatty acyl CoA synthetase 3 Luciferin 4-monooxygenase   550 aa 491 aa 23.6 %
Mycobacterium leprae PROBABLE FATTY-ACID--CoA LIGASE FADD21 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) Luciferin 4-monooxygenase   550 aa 565 aa 22.8 %
Neospora caninum acetyl-coenzyme a synthetase, putative Luciferin 4-monooxygenase   550 aa 549 aa 20.9 %
Dictyostelium discoideum hypothetical protein Luciferin 4-monooxygenase   550 aa 507 aa 20.9 %
Toxoplasma gondii propionate-CoA ligase Luciferin 4-monooxygenase   550 aa 550 aa 21.1 %
Neospora caninum Short-chain dehydrogenase/reductase SDR, related Luciferin 4-monooxygenase   550 aa 518 aa 19.1 %
Mycobacterium ulcerans non-ribosomal peptide synthetase Luciferin 4-monooxygenase   550 aa 541 aa 22.4 %
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD34 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) Luciferin 4-monooxygenase   550 aa 537 aa 20.9 %
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein Luciferin 4-monooxygenase   550 aa 476 aa 22.5 %
Mycobacterium leprae Probable fatty-acid-CoA ligase FadD9 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) Luciferin 4-monooxygenase   550 aa 461 aa 22.3 %
Leishmania infantum long chain fatty Acyl CoA synthetase, putative Luciferin 4-monooxygenase   550 aa 500 aa 23.4 %
Mycobacterium tuberculosis Probable peptide synthetase Nrp (peptide synthase) Luciferin 4-monooxygenase   550 aa 509 aa 22.6 %
Candida albicans similar to S. cerevisiae ACS2 (YLR153C) acetyl-CoA synthetase Luciferin 4-monooxygenase   550 aa 543 aa 24.5 %
Leishmania mexicana long chain fatty Acyl CoA synthetase, putative Luciferin 4-monooxygenase   550 aa 483 aa 23.8 %
Brugia malayi AMP-binding enzyme family protein Luciferin 4-monooxygenase   550 aa 497 aa 24.7 %
Loa Loa (eye worm) AMP-binding enzyme family protein Luciferin 4-monooxygenase   550 aa 489 aa 23.3 %
Dictyostelium discoideum hypothetical protein Luciferin 4-monooxygenase   550 aa 522 aa 19.9 %
Leishmania donovani long chain fatty Acyl CoA synthetase, putative Luciferin 4-monooxygenase   550 aa 500 aa 23.4 %
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD8 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) Luciferin 4-monooxygenase   550 aa 505 aa 28.1 %
Onchocerca volvulus Luciferin 4-monooxygenase   550 aa 487 aa 23.8 %
Mycobacterium ulcerans fatty-acid-CoA ligase FadD9 Luciferin 4-monooxygenase   550 aa 463 aa 21.8 %
Mycobacterium ulcerans acyl-CoA synthetase Luciferin 4-monooxygenase   550 aa 497 aa 19.3 %
Brugia malayi AMP-binding enzyme family protein Luciferin 4-monooxygenase   550 aa 544 aa 21.5 %
Mycobacterium ulcerans non-ribosomal peptide synthetase MbtE Luciferin 4-monooxygenase   550 aa 502 aa 22.5 %
Toxoplasma gondii type I fatty acid synthase, putative Luciferin 4-monooxygenase   550 aa 514 aa 19.8 %
Dictyostelium discoideum hypothetical protein Luciferin 4-monooxygenase   550 aa 539 aa 19.1 %
Dictyostelium discoideum AMP-dependent synthetase and ligase domain-containing protein Luciferin 4-monooxygenase   550 aa 531 aa 19.0 %
Candida albicans similar to S. cerevisiae ACS2 (YLR153C) acetyl-CoA synthetase Luciferin 4-monooxygenase   550 aa 539 aa 22.1 %
Onchocerca volvulus Matrilysin homolog Luciferin 4-monooxygenase   550 aa 466 aa 24.2 %
Trichomonas vaginalis AMP dependent ligase/synthetase, putative Luciferin 4-monooxygenase   550 aa 494 aa 24.3 %
Schistosoma japonicum ko:K01897 long-chain fatty-acid-CoA ligase [EC6.2.1.3], putative Luciferin 4-monooxygenase   550 aa 466 aa 27.3 %
Trichomonas vaginalis AMP dependent ligase, putative Luciferin 4-monooxygenase   550 aa 445 aa 26.1 %
Dictyostelium discoideum AMP-dependent synthetase and ligase domain-containing protein Luciferin 4-monooxygenase   550 aa 545 aa 24.9 %
Cryptosporidium hominis acyl-CoA synthetase Luciferin 4-monooxygenase   550 aa 460 aa 26.1 %
Mycobacterium tuberculosis P-hydroxybenzoyl-AMP ligase FadD22 Luciferin 4-monooxygenase   550 aa 493 aa 22.1 %
Mycobacterium tuberculosis Probable fatty-acid-AMP ligase FadD23 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) Luciferin 4-monooxygenase   550 aa 542 aa 23.8 %
Dictyostelium discoideum hypothetical protein Luciferin 4-monooxygenase   550 aa 538 aa 21.8 %
Mycobacterium ulcerans non-ribosomal peptide synthetase MbtF Luciferin 4-monooxygenase   550 aa 558 aa 20.1 %
Dictyostelium discoideum hypothetical protein Luciferin 4-monooxygenase   550 aa 538 aa 21.8 %
Dictyostelium discoideum acetyl-CoA ligase Luciferin 4-monooxygenase   550 aa 549 aa 22.2 %
Dictyostelium discoideum hypothetical protein Luciferin 4-monooxygenase   550 aa 539 aa 19.1 %
Dictyostelium discoideum hypothetical protein Luciferin 4-monooxygenase   550 aa 542 aa 18.3 %
Mycobacterium tuberculosis Fatty-acid-AMP ligase FadD32 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase). Also shown to have acyl-ACP ligase activity. Luciferin 4-monooxygenase   550 aa 487 aa 22.4 %
Leishmania braziliensis long chain fatty Acyl CoA synthetase, putative Luciferin 4-monooxygenase   550 aa 496 aa 22.8 %
Trypanosoma cruzi fatty acyl CoA synthetase, putative Luciferin 4-monooxygenase   550 aa 480 aa 25.2 %
Dictyostelium discoideum hypothetical protein Luciferin 4-monooxygenase   550 aa 542 aa 22.1 %
Dictyostelium discoideum hypothetical protein Luciferin 4-monooxygenase   550 aa 541 aa 21.4 %
Trichomonas vaginalis AMP dependent ligase/synthetase, putative Luciferin 4-monooxygenase   550 aa 554 aa 22.9 %
Echinococcus multilocularis long chain fatty acid coenzyme A ligase 5 Luciferin 4-monooxygenase   550 aa 458 aa 25.5 %
Trypanosoma cruzi fatty acyl CoA synthetase 2, putative Luciferin 4-monooxygenase   550 aa 495 aa 22.6 %
Trichomonas vaginalis AMP dependent CoA ligase, putative Luciferin 4-monooxygenase   550 aa 527 aa 25.0 %
Trichomonas vaginalis AMP dependent ligase/synthetase, putative Luciferin 4-monooxygenase   550 aa 476 aa 23.5 %
Dictyostelium discoideum fatty acyl-CoA synthetase Luciferin 4-monooxygenase   550 aa 462 aa 23.8 %
Entamoeba histolytica acyl-CoA synthetase, putative Luciferin 4-monooxygenase   550 aa 446 aa 22.0 %
Mycobacterium ulcerans acyl-CoA synthetase Luciferin 4-monooxygenase   550 aa 593 aa 22.1 %
Dictyostelium discoideum hypothetical protein Luciferin 4-monooxygenase   550 aa 535 aa 22.6 %
Leishmania braziliensis acetyl-CoA synthetase, putative Luciferin 4-monooxygenase   550 aa 596 aa 21.1 %
Cryptosporidium parvum acetyl-coenzyme A synthetase Luciferin 4-monooxygenase   550 aa 545 aa 22.8 %
Mycobacterium ulcerans peptide synthetase Nrp (peptide synthase) Luciferin 4-monooxygenase   550 aa 535 aa 23.2 %
Echinococcus multilocularis long chain fatty acid coenzyme A ligase 1 Luciferin 4-monooxygenase   550 aa 443 aa 26.4 %
Mycobacterium ulcerans long-chain-fatty-acid-CoA ligase FadD15 Luciferin 4-monooxygenase   550 aa 482 aa 24.3 %
Echinococcus multilocularis long chain fatty acid coenzyme A ligase 1 Luciferin 4-monooxygenase   550 aa 459 aa 27.0 %
Dictyostelium discoideum hypothetical protein Luciferin 4-monooxygenase   550 aa 541 aa 21.6 %
Dictyostelium discoideum hypothetical protein Luciferin 4-monooxygenase   550 aa 558 aa 20.4 %
Mycobacterium tuberculosis Probable fatty-acid-AMP ligase FadD24 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) Luciferin 4-monooxygenase   550 aa 526 aa 21.9 %
Dictyostelium discoideum hypothetical protein Luciferin 4-monooxygenase   550 aa 541 aa 21.6 %
Trypanosoma brucei gambiense fatty acyl CoA synthetase 4, putative Luciferin 4-monooxygenase   550 aa 497 aa 23.7 %
Mycobacterium tuberculosis Fatty-acid-AMP ligase FadD26 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) Luciferin 4-monooxygenase   550 aa 560 aa 21.4 %
Babesia bovis fatty acyl-CoA synthetase family protein Luciferin 4-monooxygenase   550 aa 461 aa 23.4 %
Mycobacterium tuberculosis Fatty-acid-AMP ligase FadD29 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) Luciferin 4-monooxygenase   550 aa 617 aa 22.2 %
Candida albicans similar to S. cerevisiae ACS2 (YLR153C) acetyl-CoA synthetase Luciferin 4-monooxygenase   550 aa 539 aa 22.1 %
Mycobacterium leprae Probable fatty-acid-CoA synthetase FadD28 (fatty-acid-CoA ligase) (fatty-acid-CoA synthase) Luciferin 4-monooxygenase   550 aa 484 aa 20.5 %
Mycobacterium leprae Probable long-chain-fatty-acid-CoA ligase FadD15 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) Luciferin 4-monooxygenase   550 aa 484 aa 23.3 %
Echinococcus multilocularis long chain fatty acid transport protein 4 Luciferin 4-monooxygenase   550 aa 476 aa 22.3 %
Echinococcus granulosus long chain fatty acid coenzyme A ligase 1 Luciferin 4-monooxygenase   550 aa 452 aa 26.1 %
Trypanosoma congolense fatty acyl CoA synthetase 2, putative Luciferin 4-monooxygenase   550 aa 500 aa 22.4 %
Theileria parva long-chain fatty acid CoA ligase, putative Luciferin 4-monooxygenase   550 aa 507 aa 23.5 %
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD9 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) Luciferin 4-monooxygenase   550 aa 480 aa 22.5 %
Trichomonas vaginalis AMP dependent CoA ligase, putative Luciferin 4-monooxygenase   550 aa 524 aa 24.0 %
Schistosoma japonicum ko:K01897 long-chain fatty-acid-CoA ligase [EC6.2.1.3], putative Luciferin 4-monooxygenase   550 aa 541 aa 22.4 %
Dictyostelium discoideum hypothetical protein Luciferin 4-monooxygenase   550 aa 478 aa 21.1 %
Leishmania mexicana acetyl-CoA synthetase, putative Luciferin 4-monooxygenase   550 aa 559 aa 20.6 %
Mycobacterium leprae Probable fatty-acid-CoA synthetase FadD32 (fatty-acid-CoA ligase) (fatty-acid-CoA synthase) Luciferin 4-monooxygenase   550 aa 442 aa 23.5 %
Cryptosporidium parvum acyl-CoA synthetase Luciferin 4-monooxygenase   550 aa 460 aa 25.7 %
Trichomonas vaginalis AMP dependent ligase/synthetase, putative Luciferin 4-monooxygenase   550 aa 526 aa 22.4 %
Dictyostelium discoideum AMP-dependent synthetase and ligase domain-containing protein Luciferin 4-monooxygenase   550 aa 550 aa 20.9 %
Mycobacterium leprae Probable fatty-acid-CoA synthetase FadD29 (fatty-acid-CoA ligase) (fatty-acid-CoA synthase) Luciferin 4-monooxygenase   550 aa 529 aa 22.3 %
Candida albicans similar to S. cerevisiae FAT1 (YBR041W) fatty acid transporter and very long-chain fatty acyl-CoA synthetase Luciferin 4-monooxygenase   550 aa 496 aa 24.2 %
Echinococcus granulosus long chain fatty acid transport protein 4 Luciferin 4-monooxygenase   550 aa 476 aa 22.3 %
Trichomonas vaginalis long-chain-fatty-acid CoA ligase, putative Luciferin 4-monooxygenase   550 aa 466 aa 21.7 %
Leishmania braziliensis acetyl-CoA synthetase, putative Luciferin 4-monooxygenase   550 aa 603 aa 22.6 %
Entamoeba histolytica long-chain-fatty-acid--CoA ligase, putative Luciferin 4-monooxygenase   550 aa 494 aa 23.9 %
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Echinococcus granulosus rhodopsin orphan GPCR 0.0044 0.262 0.3332
Echinococcus multilocularis allatostatin A receptor 0.0044 0.262 0.3332
Echinococcus granulosus fmrfamide receptor 0.0044 0.262 0.3332
Brugia malayi EGF-like domain containing protein 0.0016 0.0661 0.0817
Brugia malayi AKH receptor 0.0044 0.262 0.3588
Echinococcus multilocularis slit 2 protein 0.0016 0.0661 0.0758
Leishmania major P-type H -ATPase, putative 0.001 0.0214 0.089
Echinococcus granulosus 7TM GPCR rhodopsin 0.0044 0.262 0.3332
Loa Loa (eye worm) hypothetical protein 0.0044 0.262 0.2557
Mycobacterium ulcerans hypothetical protein 0.0029 0.1543 1
Toxoplasma gondii phospholipid-translocating P-type ATPase, flippase subfamily protein 0.001 0.0214 0.1642
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0044 0.262 0.3332
Mycobacterium ulcerans acyl-CoA synthetase 0.0029 0.1543 1
Schistosoma mansoni lipoxygenase 0.008 0.5222 0.6751
Trypanosoma cruzi P-type H+-ATPase, putative 0.001 0.0214 0.2543
Mycobacterium tuberculosis Bifunctional enzyme MbtA: salicyl-AMP ligase (SAL-AMP ligase) + salicyl-S-ArCP synthetase 0.0008 0.0084 0.0546
Loa Loa (eye worm) hypothetical protein 0.0051 0.3141 0.3082
Echinococcus multilocularis rhodopsin orphan GPCR 0.0044 0.262 0.3332
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0044 0.262 0.3332
Onchocerca volvulus 0.0044 0.262 0.8296
Echinococcus multilocularis g protein coupled receptor 0.0044 0.262 0.3332
Loa Loa (eye worm) animal heme peroxidase 0.0051 0.3141 0.3082
Onchocerca volvulus 0.0044 0.262 0.8296
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD3 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.002 0.0936 0.6071
Schistosoma mansoni peptide (allatostatin)-like receptor 0.0044 0.262 0.3332
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0044 0.262 0.3332
Loa Loa (eye worm) hypothetical protein 0.0051 0.3141 0.3082
Brugia malayi Calcium binding EGF domain containing protein 0.0016 0.0661 0.0817
Onchocerca volvulus 0.0016 0.0661 0.1888
Echinococcus multilocularis phospholipid transporting ATPase IIB 0.001 0.0214 0.0171
Leishmania major vacuolar-type Ca2 -ATPase, putative 0.001 0.0214 0.089
Echinococcus multilocularis protein jagged 1 0.0016 0.0661 0.0758
Entamoeba histolytica Plasma membrane calcium-transporting ATPase, putative 0.001 0.0214 0.089
Loa Loa (eye worm) hypothetical protein 0.0021 0.1021 0.0944
Echinococcus multilocularis 7TM GPCR, rhodopsin 0.0044 0.262 0.3332
Brugia malayi EGF-like domain containing protein 0.0016 0.0661 0.0817
Trichomonas vaginalis DNA helicase recq1, putative 0.0029 0.1568 1
Schistosoma mansoni thyrotropin-releasing hormone receptor 0.0044 0.262 0.3332
Loa Loa (eye worm) hypothetical protein 0.0044 0.262 0.2557
Plasmodium vivax cation transporting ATPase, putative 0.001 0.0214 0.1386
Treponema pallidum hypothetical protein 0.001 0.0214 0.5
Echinococcus multilocularis lipoxygenase domain containing protein 0.0019 0.0852 0.1008
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0044 0.262 0.3332
Onchocerca volvulus 0.0044 0.262 0.8296
Brugia malayi G protein-coupled receptor F59B2.13 0.0044 0.262 0.3588
Trypanosoma brucei cation-transporting ATPase, putative 0.001 0.0214 0.2543
Echinococcus granulosus alpha 1A adrenergic receptor 0.0044 0.262 0.3332
Echinococcus granulosus fibropellin Ia 0.0016 0.0661 0.0758
Echinococcus multilocularis growth hormone secretagogue receptor type 1 0.0044 0.262 0.3332
Schistosoma mansoni laminin gamma-3 chain 0.0016 0.0661 0.0758
Loa Loa (eye worm) hypothetical protein 0.001 0.0214 0.0131
Loa Loa (eye worm) animal heme peroxidase 0.0051 0.3141 0.3082
Brugia malayi gonadotropin-releasing hormone receptor 2 0.0044 0.262 0.3588
Loa Loa (eye worm) doublecortin family protein 0.0019 0.0852 0.0774
Loa Loa (eye worm) hypothetical protein 0.0016 0.0661 0.0582
Trichomonas vaginalis ATPase, class VI, type 11C, putative 0.001 0.0214 0.0875
Echinococcus multilocularis serotonin receptor 0.0044 0.262 0.3332
Mycobacterium tuberculosis Probable medium chain fatty-acid-CoA ligase FadD14 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0008 0.0084 0.0546
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD2 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0029 0.1543 1
Brugia malayi Blistered cuticle protein 3 0.0051 0.3141 0.4325
Echinococcus granulosus neurogenic locus notch protein 0.0016 0.0661 0.0758
Mycobacterium tuberculosis Fatty-acid-CoA synthetase FadD17 (fatty-acid-CoA synthase) (fatty-acid-CoA ligase) 0.0008 0.0084 0.0546
Loa Loa (eye worm) RNA binding protein 0.0076 0.4994 0.4951
Echinococcus multilocularis fibropellin Ia 0.0016 0.0661 0.0758
Loa Loa (eye worm) hypothetical protein 0.0044 0.262 0.2557
Loa Loa (eye worm) hypothetical protein 0.0044 0.262 0.2557
Loa Loa (eye worm) hypothetical protein 0.0016 0.0661 0.0582
Loa Loa (eye worm) Notch2 0.0016 0.0661 0.0582
Entamoeba histolytica plasma membrane calcium ion-transporting ATPase, putative 0.001 0.0214 0.089
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0044 0.262 0.3332
Plasmodium falciparum copper-transporting ATPase 0.001 0.0214 0.1055
Brugia malayi larval opioid receptor 0.0044 0.262 0.3588
Echinococcus multilocularis G protein coupled 5 hydroxytryptamine receptor 0.0044 0.262 0.3332
Echinococcus granulosus neuropeptide s receptor 0.0044 0.262 0.3332
Schistosoma mansoni peptide (FMRFamide/neurokinin-3)-like receptor 0.0044 0.262 0.3332
Mycobacterium ulcerans long-chain-fatty-acid-CoA ligase 0.0029 0.1543 1
Brugia malayi Animal haem peroxidase family protein 0.0051 0.3141 0.4325
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.0012 0.0341 0.3248
Onchocerca volvulus 0.0044 0.262 0.8296
Echinococcus granulosus bloom syndrome protein 0.0029 0.1568 0.195
Schistosoma mansoni rab6-interacting 0.0019 0.0852 0.1008
Mycobacterium ulcerans metal cation-transporting p-type ATPase CtpC 0.001 0.0214 0.089
Loa Loa (eye worm) hypothetical protein 0.0044 0.262 0.2557
Loa Loa (eye worm) 5-hydroxytryptamine 2C receptor 0.0044 0.262 0.2557
Brugia malayi Calcium binding EGF domain containing protein 0.0016 0.0661 0.0817
Mycobacterium tuberculosis Peptide synthetase MbtF (peptide synthase) 0.0008 0.0084 0.0546
Loa Loa (eye worm) hypothetical protein 0.0021 0.1021 0.0944
Onchocerca volvulus Dopamine\/Ecdysteroid receptor homolog 0.0044 0.262 0.8296
Echinococcus multilocularis RUN 0.0019 0.0852 0.1008
Echinococcus multilocularis thyrotropin releasing hormone receptor 0.0044 0.262 0.3332
Echinococcus granulosus phospholipid transporting ATPase VA 0.001 0.0214 0.0171
Echinococcus multilocularis bloom syndrome protein 0.0029 0.1568 0.195
Loa Loa (eye worm) hypothetical protein 0.0044 0.262 0.2557
Schistosoma mansoni cation-transporting atpase worm 0.001 0.0214 0.0171
Schistosoma mansoni opsin-like receptor 0.0044 0.262 0.3332
Onchocerca volvulus 0.0044 0.262 0.8296
Schistosoma mansoni amine GPCR 0.0044 0.262 0.3332
Onchocerca volvulus 0.0044 0.262 0.8296
Echinococcus granulosus neuropeptide FF receptor 2 0.0044 0.262 0.3332
Schistosoma mansoni biogenic amine (5HT) receptor 0.0044 0.262 0.3332
Schistosoma mansoni hypothetical protein 0.0016 0.0661 0.0758
Trichomonas vaginalis plasma membrane calcium-transporting ATPase, putative 0.001 0.0214 0.0875
Onchocerca volvulus Peroxidase homolog 0.0051 0.3141 1
Onchocerca volvulus 0.0044 0.262 0.8296
Schistosoma mansoni ancient conserved domain protein 2 (cyclin m2) 0.0044 0.262 0.3332
Echinococcus multilocularis phosphoserine phosphatase 0.001 0.0214 0.0171
Entamoeba histolytica Plasma membrane calcium-transporting ATPase, putative 0.001 0.0214 0.089
Loa Loa (eye worm) E1-E2 ATPase 0.001 0.0214 0.0131
Loa Loa (eye worm) hypothetical protein 0.0044 0.262 0.2557
Trichomonas vaginalis plasma membrane calcium-transporting ATPase, putative 0.001 0.0214 0.0875
Onchocerca volvulus 0.0029 0.1543 0.4771
Brugia malayi Animal haem peroxidase family protein 0.0051 0.3141 0.4325
Trichomonas vaginalis plasma membrane calcium-transporting ATPase, putative 0.001 0.0214 0.0875
Echinococcus multilocularis G protein coupled receptor 139 0.0044 0.262 0.3332
Mycobacterium ulcerans cation-transporter p-type ATPase B CtpB 0.001 0.0214 0.089
Echinococcus multilocularis rhodopsin orphan GPCR 0.0044 0.262 0.3332
Schistosoma mansoni neuropeptide receptor 0.0044 0.262 0.3332
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0044 0.262 0.3332
Schistosoma mansoni hypothetical protein 0.0016 0.0661 0.0758
Mycobacterium ulcerans acyl-CoA synthetase 0.0029 0.1543 1
Echinococcus multilocularis phosphoserine phosphatase 0.001 0.0214 0.0171
Echinococcus multilocularis biogenic amine (5HT) receptor 0.0044 0.262 0.3332
Echinococcus multilocularis copper transporting ATPase 1 0.001 0.0214 0.0171
Onchocerca volvulus 0.0051 0.3141 1
Loa Loa (eye worm) hypothetical protein 0.0021 0.1021 0.0944
Toxoplasma gondii sarco/endoplasmic reticulum Ca2+-ATPase 0.001 0.0214 0.1642
Echinococcus granulosus dro:myosuppressin receptor 0.0044 0.262 0.3332
Chlamydia trachomatis acylglycerophosphoethanolamine acyltransferase 0.0021 0.1021 1
Brugia malayi hypothetical protein 0.001 0.0214 0.0184
Loa Loa (eye worm) neuropeptide F receptor 0.0044 0.262 0.2557
Brugia malayi Peroxidasin 0.0051 0.3141 0.4325
Brugia malayi Dopamine receptor protein 1, putative (partial) 0.0044 0.262 0.3588
Brugia malayi Delta serrate ligand family protein 0.0016 0.0661 0.0817
Schistosoma mansoni cation-transporting atpase 13a1 (G-box binding protein) 0.001 0.0214 0.0171
Brugia malayi Dopamine receptor protein 1 0.0044 0.262 0.3588
Plasmodium falciparum acyl-CoA synthetase 0.0021 0.1021 0.7611
Onchocerca volvulus Peroxidasin homolog 0.0051 0.3141 1
Trypanosoma brucei P-type H+-ATPase, putative 0.001 0.0214 0.2543
Echinococcus multilocularis Tetracycline resistance leader peptide, TetL 0.001 0.0214 0.0171
Schistosoma mansoni neuropeptide F-like receptor 0.0044 0.262 0.3332
Echinococcus granulosus cation transporting ATPase 13A1 0.001 0.0214 0.0171
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0044 0.262 0.3332
Trypanosoma cruzi phospholipid-transporting ATPase-like protein, putative 0.001 0.0214 0.2543
Echinococcus granulosus copper transporting ATPase 1 0.001 0.0214 0.0171
Echinococcus granulosus allatostatin A receptor 0.0044 0.262 0.3332
Trypanosoma brucei ATP-dependent DEAD/H DNA helicase recQ, putative 0.0015 0.0595 1
Trichomonas vaginalis plasma membrane calcium-transporting ATPase, putative 0.001 0.0214 0.0875
Onchocerca volvulus Chorion peroxidase homolog 0.0051 0.3141 1
Loa Loa (eye worm) hypothetical protein 0.0044 0.262 0.2557
Loa Loa (eye worm) hypothetical protein 0.0019 0.0852 0.0774
Echinococcus multilocularis peptide (allatostatin:somatostatin) 0.0044 0.262 0.3332
Echinococcus multilocularis fmrfamide receptor 0.0044 0.262 0.3332
Brugia malayi haloacid dehalogenase-like hydrolase family protein 0.001 0.0214 0.0184
Loa Loa (eye worm) hypothetical protein 0.0012 0.0341 0.0259
Schistosoma mansoni eyes absent homolog 0.0106 0.7151 0.9287
Brugia malayi hypothetical protein 0.0044 0.262 0.3588
Echinococcus granulosus 7tm_1 domain containing protein 0.0044 0.262 0.3332
Echinococcus multilocularis calcium transporting ATPase type 2C member 0.001 0.0214 0.0171
Brugia malayi Animal haem peroxidase family protein 0.0051 0.3141 0.4325
Trypanosoma cruzi proton motive ATPase 1, putative 0.001 0.0214 0.2543
Echinococcus multilocularis phosphoserine phosphatase 0.001 0.0214 0.0171
Echinococcus granulosus protein jagged 2 0.0016 0.0661 0.0758
Onchocerca volvulus Dual oxidase homolog 0.0051 0.3141 1
Loa Loa (eye worm) hypothetical protein 0.0044 0.262 0.2557
Schistosoma mansoni loxhd1 0.0019 0.0852 0.1008
Loa Loa (eye worm) hypothetical protein 0.0051 0.3141 0.3082
Mycobacterium tuberculosis Probable cation transporter P-type ATPase D CtpD 0.001 0.0214 0.1388
Echinococcus granulosus RUN 0.0019 0.0852 0.1008
Brugia malayi hypothetical protein 0.0106 0.7151 1
Toxoplasma gondii phospholipid-translocating P-type ATPase, flippase subfamily protein 0.001 0.0214 0.1642
Entamoeba histolytica phospholipid-transporting P-type ATPase, putative 0.001 0.0214 0.089
Leishmania major vacuolar-type Ca2 -ATPase, putative 0.001 0.0214 0.089
Echinococcus granulosus neural cadherin 0.0016 0.0661 0.0758
Brugia malayi notch-like transmembrane receptor 0.0016 0.0661 0.0817
Echinococcus multilocularis rhodopsin orphan GPCR 0.0044 0.262 0.3332
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD7 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0029 0.1543 1
Schistosoma mansoni myosin xvIII 0.0044 0.262 0.3332
Plasmodium falciparum ATP-dependent DNA helicase Q1 0.0012 0.0341 0.2087
Brugia malayi EGF-like domain containing protein 0.0016 0.0661 0.0817
Loa Loa (eye worm) hypothetical protein 0.0051 0.3141 0.3082
Echinococcus multilocularis lipoxygenase domain containing protein 0.0019 0.0852 0.1008
Onchocerca volvulus 0.0051 0.3141 1
Loa Loa (eye worm) hypothetical protein 0.0044 0.262 0.2557
Echinococcus multilocularis rhodopsin orphan GPCR 0.0044 0.262 0.3332
Loa Loa (eye worm) hypothetical protein 0.0016 0.0661 0.0582
Onchocerca volvulus 0.0016 0.0661 0.1888
Echinococcus granulosus tm gpcr rhodopsin 0.0044 0.262 0.3332
Echinococcus multilocularis tachykinin peptides receptor 99D 0.0044 0.262 0.3332
Schistosoma mansoni hypothetical protein 0.0016 0.0661 0.0758
Loa Loa (eye worm) hypothetical protein 0.0044 0.262 0.2557
Brugia malayi hypothetical protein 0.0019 0.0852 0.1086
Brugia malayi ATP-dependent DNA helicase, RecQ family protein 0.0012 0.0341 0.0363
Schistosoma mansoni cation-transporting atpase worm 0.001 0.0214 0.0171
Loa Loa (eye worm) hypothetical protein 0.0044 0.262 0.2557
Echinococcus granulosus serotonin receptor 0.0044 0.262 0.3332
Brugia malayi E1-E2 ATPase family protein 0.001 0.0214 0.0184
Trypanosoma cruzi copper-transporting ATPase-like protein, putative 0.001 0.0214 0.2543
Schistosoma mansoni notch 0.0016 0.0661 0.0758
Echinococcus granulosus rhodopsin orphan GPCR 0.0044 0.262 0.3332
Echinococcus granulosus cation transporting ATPase 13A3 0.001 0.0214 0.0171
Mycobacterium tuberculosis Peptide synthetase MbtE (peptide synthase) 0.0008 0.0084 0.0546
Toxoplasma gondii P-type ATPase PMA1 0.001 0.0214 0.1642
Trichomonas vaginalis cation-transporting ATPase, putative 0.001 0.0214 0.0875
Echinococcus granulosus pyroglutamylated rfamide peptide receptor 0.0044 0.262 0.3332
Onchocerca volvulus 0.0044 0.262 0.8296
Schistosoma mansoni rab6-interacting 0.0019 0.0852 0.1008
Echinococcus granulosus neuropeptide receptor A26 0.0044 0.262 0.3332
Brugia malayi Bloom's syndrome protein homolog 0.0029 0.1568 0.21
Echinococcus multilocularis Polycystic kidney disease protein 0.0019 0.0852 0.1008
Trypanosoma cruzi plasma membrane Ca2+ ATPase 0.001 0.0214 0.2543
Loa Loa (eye worm) TAR-binding protein 0.0076 0.4994 0.4951
Onchocerca volvulus 0.0016 0.0661 0.1888
Echinococcus multilocularis sarco:endoplasmic reticulum calcium ATPase 0.001 0.0214 0.0171
Echinococcus granulosus neurogenic locus notch protein 4 0.0016 0.0661 0.0758
Loa Loa (eye worm) hypothetical protein 0.0051 0.3141 0.3082
Echinococcus granulosus ATP dependent DNA helicase Q5 0.0012 0.0341 0.0337
Onchocerca volvulus Putative cubilin 0.0016 0.0661 0.1888
Schistosoma mansoni tar DNA-binding protein 0.0076 0.4994 0.6452
Brugia malayi EGF-like domain containing protein 0.0016 0.0661 0.0817
Loa Loa (eye worm) hypothetical protein 0.0051 0.3141 0.3082
Entamoeba histolytica recQ family helicase, putative 0.0015 0.0595 0.3501
Schistosoma mansoni notch 0.0016 0.0661 0.0758
Echinococcus multilocularis serotonin receptor 0.0044 0.262 0.3332
Mycobacterium ulcerans long-chain fatty-acid CoA ligase 0.0029 0.1543 1
Echinococcus granulosus plasma membrane calcium transporting ATPase 2 0.001 0.0214 0.0171
Mycobacterium tuberculosis Fatty-acid-AMP ligase FadD30 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) 0.0021 0.1021 0.6617
Trichomonas vaginalis cation-transporting ATPase, putative 0.001 0.0214 0.0875
Echinococcus multilocularis peroxidasin 0.0051 0.3141 0.4017
Echinococcus multilocularis fmrfamide receptor 0.0044 0.262 0.3332
Loa Loa (eye worm) hypothetical protein 0.0021 0.1021 0.0944
Loa Loa (eye worm) hypothetical protein 0.001 0.0214 0.0131
Echinococcus multilocularis phosphoserine phosphatase 0.001 0.0214 0.0171
Loa Loa (eye worm) hypothetical protein 0.0044 0.262 0.2557
Brugia malayi G protein-coupled receptor 0.0044 0.262 0.3588
Loa Loa (eye worm) hypothetical protein 0.0044 0.262 0.2557
Echinococcus granulosus ATP dependent DNA helicase Q1 0.0012 0.0341 0.0337
Brugia malayi potential phospholipid-transporting ATPase IIB, putative 0.001 0.0214 0.0184
Echinococcus granulosus orexin receptor type 2 0.0044 0.262 0.3332
Leishmania major proton motive ATPase, putative 0.001 0.0214 0.089
Brugia malayi Tachykinin-like peptides receptor 99D 0.0044 0.262 0.3588
Echinococcus multilocularis neurogenic locus notch protein 0.0016 0.0661 0.0758
Toxoplasma gondii EGF family domain-containing protein 0.0016 0.0661 0.7301
Echinococcus multilocularis rhodopsin orphan GPCR 0.0044 0.262 0.3332
Loa Loa (eye worm) unidentified vitellogenin-linked transcript protein 6 0.0044 0.262 0.2557
Echinococcus granulosus protein jagged 1 0.0016 0.0661 0.0758
Brugia malayi hypothetical protein 0.0044 0.262 0.3588
Loa Loa (eye worm) ATP-dependent DNA helicase 0.0012 0.0341 0.0259
Echinococcus multilocularis cation transporting ATPase 13A3 0.001 0.0214 0.0171
Schistosoma mansoni tar DNA-binding protein 0.0076 0.4994 0.6452
Echinococcus granulosus Polycystic kidney disease protein 0.0019 0.0852 0.1008
Loa Loa (eye worm) hypothetical protein 0.001 0.0214 0.0131
Echinococcus multilocularis g-protein coupled receptor 0.0044 0.262 0.3332
Echinococcus granulosus protein jagged 1 0.0016 0.0661 0.0758
Loa Loa (eye worm) hypothetical protein 0.0016 0.0661 0.0582
Echinococcus granulosus protein jagged 2 0.0016 0.0661 0.0758
Echinococcus granulosus hypothetical protein 0.0044 0.262 0.3332
Schistosoma mansoni hypothetical protein 0.0044 0.262 0.3332
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0044 0.262 0.3332
Brugia malayi hypothetical protein 0.0044 0.262 0.3588
Echinococcus multilocularis cation transporting ATPase 13A1 0.001 0.0214 0.0171
Echinococcus multilocularis neuropeptide s receptor 0.0044 0.262 0.3332
Schistosoma mansoni tar DNA-binding protein 0.0076 0.4994 0.6452
Onchocerca volvulus Slit protein homolog 0.0016 0.0661 0.1888
Trichomonas vaginalis phospholipid-transporting ATPase, putative 0.001 0.0214 0.0875
Schistosoma mansoni Pro-neuregulin-4 membrane-bound isoform (Pro-NRG4) [Contains: Neuregulin-4 (NRG-4)] 0.0016 0.0661 0.0758
Echinococcus multilocularis fat cadherin tumor suppressor 0.0016 0.0661 0.0758
Schistosoma mansoni slit 0.0016 0.0661 0.0758
Schistosoma mansoni phosphoserine phosphatase 0.001 0.0214 0.0171
Echinococcus granulosus rhodopsin orphan GPCR 0.0044 0.262 0.3332
Echinococcus multilocularis phospholipid transporting ATPase VA 0.001 0.0214 0.0171
Trichomonas vaginalis DNA helicase recq, putative 0.0015 0.0595 0.344
Echinococcus granulosus neuropeptide Y receptor 0.0044 0.262 0.3332
Onchocerca volvulus 0.0044 0.262 0.8296
Onchocerca volvulus Neuropeptide F receptor homolog 0.0044 0.262 0.8296
Brugia malayi Transmembrane cell adhesion receptor mua-3 precursor, putative 0.0016 0.0661 0.0817
Loa Loa (eye worm) hypothetical protein 0.0016 0.0661 0.0582
Mycobacterium leprae Probable metal cation-transporting P-type ATPase C CtpC 0.001 0.0214 0.089
Mycobacterium tuberculosis Probable chain -fatty-acid-CoA ligase FadD13 (fatty-acyl-CoA synthetase) 0.0029 0.1543 1
Schistosoma mansoni neuropeptide F-like receptor 0.0044 0.262 0.3332
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0044 0.262 0.3332
Echinococcus multilocularis pyroglutamylated rfamide peptide receptor 0.0044 0.262 0.3332
Brugia malayi G-protein coupled receptor 0.0044 0.262 0.3588
Echinococcus granulosus rhodopsin orphan GPCR 0.0044 0.262 0.3332
Brugia malayi Melatonin receptor type 1A 0.0044 0.262 0.3588
Loa Loa (eye worm) hypothetical protein 0.0016 0.0661 0.0582
Trichomonas vaginalis plasma membrane calcium-transporting ATPase, putative 0.001 0.0214 0.0875
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0044 0.262 0.3332
Loa Loa (eye worm) hypothetical protein 0.0051 0.3141 0.3082
Mycobacterium ulcerans metal cation-transporting p-type ATPase F, CtpF 0.001 0.0214 0.089
Plasmodium falciparum non-SERCA-type Ca2+ -transporting P-ATPase 0.001 0.0214 0.1055
Brugia malayi hypothetical protein 0.0044 0.262 0.3588
Schistosoma mansoni septate junction protein 0.0016 0.0661 0.0758
Onchocerca volvulus 0.0044 0.262 0.8296
Brugia malayi EGF-like domain containing protein 0.0016 0.0661 0.0817
Echinococcus granulosus g protein coupled receptor 0.0044 0.262 0.3332
Loa Loa (eye worm) hypothetical protein 0.0044 0.262 0.2557
Schistosoma mansoni neuropeptide receptor 0.0044 0.262 0.3332
Plasmodium vivax multidomain scavenger receptor, putative 0.0019 0.0852 0.8194
Echinococcus multilocularis neurogenic locus protein delta 0.0016 0.0661 0.0758
Echinococcus granulosus slit 2 protein 0.0016 0.0661 0.0758
Loa Loa (eye worm) hypothetical protein 0.0044 0.262 0.2557
Echinococcus granulosus neuropeptides capa receptor 0.0044 0.262 0.3332
Brugia malayi follicle stimulating hormone receptor 0.0044 0.262 0.3588
Echinococcus granulosus biogenic amine 5HT receptor 0.0044 0.262 0.3332
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD8 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0008 0.0084 0.0546
Schistosoma mansoni type V p-type atpase isoform 0.001 0.0214 0.0171
Echinococcus granulosus neuropeptide receptor 0.0044 0.262 0.3332
Mycobacterium ulcerans long-chain-fatty-acid--CoA ligase 0.0029 0.1543 1
Brugia malayi Dopamine receptor 0.0044 0.262 0.3588
Loa Loa (eye worm) animal heme peroxidase 0.0051 0.3141 0.3082
Loa Loa (eye worm) neuropeptide F receptor 0.0044 0.262 0.2557
Schistosoma mansoni growth hormone secretagogue receptor 0.0044 0.262 0.3332
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0029 0.1543 1
Schistosoma mansoni biogenic amine (5HT) receptor 0.0044 0.262 0.3332
Brugia malayi AMP-binding enzyme family protein 0.0029 0.1543 0.2064
Loa Loa (eye worm) hypothetical protein 0.0044 0.262 0.2557
Onchocerca volvulus 0.0044 0.262 0.8296
Loa Loa (eye worm) hypothetical protein 0.0051 0.3141 0.3082
Loa Loa (eye worm) hypothetical protein 0.0051 0.3141 0.3082
Echinococcus granulosus G protein coupled receptor 139 0.0044 0.262 0.3332
Brugia malayi RE15519p 0.0044 0.262 0.3588
Loa Loa (eye worm) hypothetical protein 0.0044 0.262 0.2557
Brugia malayi Serotonin receptor 0.0044 0.262 0.3588
Mycobacterium tuberculosis Probable peptide synthetase Nrp (peptide synthase) 0.0008 0.0084 0.0546
Echinococcus multilocularis neurogenic locus notch protein 0.0016 0.0661 0.0758
Echinococcus granulosus neurogenic locus notch protein 0.0016 0.0661 0.0758
Brugia malayi ORL1-like opioid receptor 0.0044 0.262 0.3588
Schistosoma mansoni ATPase 0.001 0.0214 0.0171
Brugia malayi E1-E2 ATPase family protein 0.001 0.0214 0.0184
Schistosoma mansoni tar DNA-binding protein 0.0076 0.4994 0.6452
Loa Loa (eye worm) hypothetical protein 0.0016 0.0661 0.0582
Brugia malayi hypothetical protein 0.0019 0.0852 0.1086
Schistosoma mansoni neuropeptide f receptor 76f 0.0044 0.262 0.3332
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD35 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.002 0.0936 0.6071
Treponema pallidum cation-transporting ATPase, P-type 0.001 0.0214 0.5
Echinococcus granulosus G protein coupled 5 hydroxytryptamine receptor 0.0044 0.262 0.3332
Loa Loa (eye worm) calcium ATPase 0.001 0.0214 0.0131
Schistosoma mansoni peroxidasin 0.0051 0.3141 0.4017
Mycobacterium tuberculosis Probable metal cation transporter P-type ATPase CtpV 0.001 0.0214 0.1388
Loa Loa (eye worm) G-protein coupled receptor 0.0044 0.262 0.2557
Schistosoma mansoni opsin-like receptor 0.0044 0.262 0.3332
Loa Loa (eye worm) hypothetical protein 0.0016 0.0661 0.0582
Echinococcus granulosus rhodopsin orphan GPCR 0.0044 0.262 0.3332
Mycobacterium tuberculosis Possible metal cation transporting P-type ATPase CtpH 0.001 0.0214 0.1388
Schistosoma mansoni histamine-responsive GPCR (AAF21638) 0.0044 0.262 0.3332
Loa Loa (eye worm) G-protein coupled receptor 0.0044 0.262 0.2557
Echinococcus multilocularis neurogenic locus protein delta 0.0016 0.0661 0.0758
Loa Loa (eye worm) hypothetical protein 0.0044 0.262 0.2557
Echinococcus multilocularis g protein coupled receptor 0.0044 0.262 0.3332
Trichomonas vaginalis cation-transporting ATPase, putative 0.001 0.0214 0.0875
Brugia malayi hypothetical protein 0.0044 0.262 0.3588
Schistosoma mansoni peptide (allatostatin/somatostatin)-like receptor 0.0044 0.262 0.3332
Entamoeba histolytica phospholipid-transporting P-type ATPase, putative 0.001 0.0214 0.089
Loa Loa (eye worm) hypothetical protein 0.0044 0.262 0.2557
Mycobacterium ulcerans metal cation transporter ATPase p-type CtpE 0.001 0.0214 0.089
Plasmodium falciparum ADP-dependent DNA helicase RecQ 0.0025 0.1315 1
Mycobacterium ulcerans cation transporter p-type ATPase D CtpD 0.001 0.0214 0.089
Schistosoma mansoni adenoreceptor 0.0044 0.262 0.3332
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD7 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.002 0.0936 0.6071
Loa Loa (eye worm) RNA recognition domain-containing protein domain-containing protein 0.0076 0.4994 0.4951
Loa Loa (eye worm) Na,K-ATPase alpha subunit 0.001 0.0214 0.0131
Toxoplasma gondii haloacid dehalogenase family hydrolase domain-containing protein 0.001 0.0214 0.1642
Schistosoma mansoni peroxidasin 0.0051 0.3141 0.4017
Echinococcus granulosus lipoxygenase domain containing protein 0.0019 0.0852 0.1008
Schistosoma mansoni hypothetical protein 0.0044 0.262 0.3332
Brugia malayi hypothetical protein 0.0044 0.262 0.3588
Loa Loa (eye worm) hypothetical protein 0.0044 0.262 0.2557
Loa Loa (eye worm) hypothetical protein 0.0016 0.0661 0.0582
Echinococcus granulosus arachidonate 5 lipoxygenase 0.0114 0.7694 1
Brugia malayi EGF-like domain containing protein 0.0016 0.0661 0.0817
Echinococcus multilocularis notch 0.0016 0.0661 0.0758
Loa Loa (eye worm) hypothetical protein 0.0016 0.0661 0.0582
Entamoeba histolytica calcium-transporting P-type ATPase, putative 0.001 0.0214 0.089
Trypanosoma cruzi copper-transporting ATPase-like protein, putative 0.001 0.0214 0.2543
Plasmodium vivax ADP-dependent DNA helicase RecQ, putative 0.002 0.0891 0.8621
Onchocerca volvulus 0.0016 0.0661 0.1888
Leishmania major P-type H -ATPase, putative 0.001 0.0214 0.089
Schistosoma mansoni hypothetical protein 0.0016 0.0661 0.0758
Brugia malayi GnHR receptor homolog 0.0044 0.262 0.3588
Schistosoma mansoni histamine h1 receptor 0.0044 0.262 0.3332
Brugia malayi Unidentified vitellogenin-linked transcript protein 6, putative 0.0044 0.262 0.3588
Trypanosoma cruzi P-type H+-ATPase, putative 0.001 0.0214 0.2543
Loa Loa (eye worm) hypothetical protein 0.0051 0.3141 0.3082
Loa Loa (eye worm) hypothetical protein 0.0044 0.262 0.2557
Echinococcus multilocularis alpha 1A adrenergic receptor 0.0044 0.262 0.3332
Trichomonas vaginalis cation-transporting ATPase fungi, putative 0.001 0.0214 0.0875
Mycobacterium tuberculosis Cation transporter P-type ATPase a CtpA 0.001 0.0214 0.1388
Schistosoma mansoni hypothetical protein 0.0016 0.0661 0.0758
Loa Loa (eye worm) hypothetical protein 0.0016 0.0661 0.0582
Onchocerca volvulus 0.0044 0.262 0.8296
Echinococcus granulosus sarco:endoplasmic reticulum calcium ATPase 0.001 0.0214 0.0171
Schistosoma mansoni notch 0.0016 0.0661 0.0758
Trypanosoma cruzi copper-transporting ATPase-like protein, putative 0.001 0.0214 0.2543
Schistosoma mansoni blooms syndrome DNA helicase 0.0023 0.1129 0.1372
Echinococcus multilocularis phosphoserine phosphatase 0.001 0.0214 0.0171
Leishmania major copper-transporting ATPase-like protein, putative 0.001 0.0214 0.089
Brugia malayi Animal haem peroxidase family protein 0.0051 0.3141 0.4325
Schistosoma mansoni ATPase 0.001 0.0214 0.0171
Brugia malayi Dopamine receptor protein 2 0.0044 0.262 0.3588
Mycobacterium tuberculosis Possible fatty-acid-CoA ligase FadD10 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0008 0.0084 0.0546
Onchocerca volvulus Neurogenic locus notch protein homolog 0.0016 0.0661 0.1888
Echinococcus granulosus lipoxygenase domain containing protein 0.0019 0.0852 0.1008
Echinococcus multilocularis neuropeptide receptor 0.0044 0.262 0.3332
Loa Loa (eye worm) hypothetical protein 0.0044 0.262 0.2557
Loa Loa (eye worm) melatonin receptor type 1A 0.0044 0.262 0.2557
Brugia malayi hypothetical protein 0.0044 0.262 0.3588
Trypanosoma cruzi plasma membrane Ca2+ ATPase 0.001 0.0214 0.2543
Echinococcus granulosus notch 0.0016 0.0661 0.0758
Loa Loa (eye worm) hypothetical protein 0.0021 0.1021 0.0944
Schistosoma mansoni alpha-1 adrenergic receptor 0.0044 0.262 0.3332
Schistosoma mansoni DNA helicase recq5 0.0012 0.0341 0.0337
Onchocerca volvulus 0.001 0.0214 0.0425
Loa Loa (eye worm) hypothetical protein 0.0044 0.262 0.2557
Schistosoma mansoni hypothetical protein 0.0044 0.262 0.3332
Loa Loa (eye worm) RecQ helicase 0.0029 0.1568 0.1497
Brugia malayi Animal haem peroxidase family protein 0.0051 0.3141 0.4325
Giardia lamblia Sgs1 DNA helicase, putative 0.0012 0.0341 0.2837
Leishmania major 4-coumarate:coa ligase-like protein 0.0029 0.1543 1
Plasmodium vivax acyl-CoA synthetase, putative 0.0021 0.1021 1
Echinococcus multilocularis somatostatin receptor 0.0044 0.262 0.3332
Onchocerca volvulus 0.0019 0.0852 0.2511
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD2 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0029 0.1543 1
Echinococcus granulosus tm gpcr rhodopsin 0.0044 0.262 0.3332
Echinococcus multilocularis cation transporting atpase worm 0.001 0.0214 0.0171
Loa Loa (eye worm) hypothetical protein 0.0016 0.0661 0.0582
Echinococcus multilocularis ATP dependent DNA helicase Q1 0.0012 0.0341 0.0337
Toxoplasma gondii cation-transporting atpase family protein 0.001 0.0214 0.1642
Brugia malayi hypothetical protein 0.0044 0.262 0.3588
Loa Loa (eye worm) hypothetical protein 0.0051 0.3141 0.3082
Echinococcus granulosus tachykinin peptides receptor 99D 0.0044 0.262 0.3332
Onchocerca volvulus 0.0044 0.262 0.8296
Entamoeba histolytica cation-transporting P-typeATPase, putative 0.001 0.0214 0.089
Leishmania major calcium-translocating P-type ATPase 0.001 0.0214 0.089
Echinococcus granulosus phospholipid transporting ATPase IIB 0.001 0.0214 0.0171
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0021 0.1021 0.6421
Loa Loa (eye worm) hypothetical protein 0.0044 0.262 0.2557
Trypanosoma brucei copper-transporting ATPase-like protein, putative 0.001 0.0214 0.2543
Echinococcus multilocularis sex peptide receptor 0.0044 0.262 0.3332
Echinococcus multilocularis neuropeptides capa receptor 0.0044 0.262 0.3332
Loa Loa (eye worm) hypothetical protein 0.001 0.0214 0.0131
Schistosoma mansoni neuropeptide receptor 0.0044 0.262 0.3332
Loa Loa (eye worm) hypothetical protein 0.0016 0.0661 0.0582
Toxoplasma gondii heavy metal translocating P-type ATPase subfamily protein 0.001 0.0214 0.1642
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0044 0.262 0.3332
Loa Loa (eye worm) hypothetical protein 0.0029 0.1543 0.1471
Onchocerca volvulus 0.0044 0.262 0.8296
Entamoeba histolytica acyl-CoA synthetase, putative 0.0029 0.1543 1
Schistosoma mansoni amine GPCR 0.0044 0.262 0.3332
Loa Loa (eye worm) hypothetical protein 0.0044 0.262 0.2557
Echinococcus multilocularis neuropeptide receptor A26 0.0044 0.262 0.3332
Mycobacterium ulcerans cation transporter p-type ATPase a CtpA 0.001 0.0214 0.089
Loa Loa (eye worm) hypothetical protein 0.0044 0.262 0.2557
Trichomonas vaginalis cation-transporting ATPase, putative 0.001 0.0214 0.0875
Brugia malayi Cadherin domain containing protein 0.0016 0.0661 0.0817
Echinococcus multilocularis ATP dependent DNA helicase Q5 0.0012 0.0341 0.0337
Mycobacterium tuberculosis Phenyloxazoline synthase MbtB (phenyloxazoline synthetase) 0.0008 0.0084 0.0546
Brugia malayi RNA recognition motif domain containing protein 0.0076 0.4994 0.6947
Echinococcus granulosus rhodopsin orphan GPCR 0.0044 0.262 0.3332
Plasmodium vivax copper-transporting ATPase, putative 0.001 0.0214 0.1386
Loa Loa (eye worm) hypothetical protein 0.0051 0.3141 0.3082
Schistosoma mansoni cell polarity protein 0.0016 0.0661 0.0758
Entamoeba histolytica phospholipid-transporting P-type ATPase, putative 0.001 0.0214 0.089
Schistosoma mansoni atpase class VI type 11c 0.001 0.0214 0.0171
Echinococcus granulosus neuropeptide Y receptor 0.0044 0.262 0.3332
Brugia malayi EGF-like domain containing protein 0.0016 0.0661 0.0817
Loa Loa (eye worm) hypothetical protein 0.0016 0.0661 0.0582
Brugia malayi AMP-binding enzyme family protein 0.0029 0.1543 0.2064
Brugia malayi Serotonin/octopamine receptor family protein 7 0.0044 0.262 0.3588
Schistosoma mansoni tar DNA-binding protein 0.0076 0.4994 0.6452
Trypanosoma cruzi cation-transporting ATPase, putative 0.001 0.0214 0.2543
Brugia malayi TAR-binding protein 0.0076 0.4994 0.6947
Loa Loa (eye worm) hypothetical protein 0.0016 0.0661 0.0582
Entamoeba histolytica plasma membrane calcium-transporting ATPase 1, putative 0.001 0.0214 0.089
Echinococcus multilocularis neuropeptide Y receptor 0.0044 0.262 0.3332
Trypanosoma cruzi copper-transporting ATPase, putative 0.001 0.0214 0.2543
Leishmania major 4-coumarate:coa ligase-like protein 0.0029 0.1543 1
Loa Loa (eye worm) notch protein 0.0016 0.0661 0.0582
Mycobacterium ulcerans metal cation transporter p-type ATPase, CtpV 0.001 0.0214 0.089
Echinococcus granulosus somatostatin receptor 0.0044 0.262 0.3332
Schistosoma mansoni cation-transporting ATPase 0.001 0.0214 0.0171
Trichomonas vaginalis DNA helicase recq, putative 0.0029 0.1568 1
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD5 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.002 0.0936 0.6071
Onchocerca volvulus 0.0044 0.262 0.8296
Mycobacterium leprae PROBABLE CATION-TRANSPORTER P-TYPE ATPASE B CTPB 0.001 0.0214 0.089
Loa Loa (eye worm) hypothetical protein 0.0044 0.262 0.2557
Brugia malayi putative neuropeptide receptor NPR1 0.0044 0.262 0.3588
Echinococcus multilocularis g protein coupled receptor 0.0044 0.262 0.3332
Schistosoma mansoni notch 0.0016 0.0661 0.0758
Echinococcus multilocularis neural cadherin 0.0016 0.0661 0.0758
Loa Loa (eye worm) hypothetical protein 0.0051 0.3141 0.3082
Brugia malayi Doublecortin family protein 0.0019 0.0852 0.1086
Loa Loa (eye worm) hypothetical protein 0.0044 0.262 0.2557
Schistosoma mansoni biogenic amine receptor 0.0044 0.262 0.3332
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0044 0.262 0.3332
Echinococcus multilocularis rhodopsin orphan GPCR 0.0044 0.262 0.3332
Loa Loa (eye worm) hypothetical protein 0.0044 0.262 0.2557
Echinococcus multilocularis G-protein coupled receptor, putative 0.0044 0.262 0.3332
Schistosoma mansoni neuropeptide receptor 0.0044 0.262 0.3332
Echinococcus granulosus neuropeptide receptor 0.0044 0.262 0.3332
Schistosoma mansoni DNA helicase recq1 0.0012 0.0341 0.0337
Echinococcus multilocularis protein jagged 2 0.0016 0.0661 0.0758
Brugia malayi sulfakinin receptor protein 0.0044 0.262 0.3588
Loa Loa (eye worm) TYRA-2 protein 0.0044 0.262 0.2557
Brugia malayi ATP-dependent DNA helicase, RecQ family protein 0.0012 0.0341 0.0363
Brugia malayi neuropeptide F receptor 0.0044 0.262 0.3588
Mycobacterium ulcerans metal cation transporter p-type ATPase a 0.001 0.0214 0.089
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.0012 0.0341 0.3248
Entamoeba histolytica acyl-CoA synthetase, putative 0.0029 0.1543 1
Loa Loa (eye worm) hypothetical protein 0.0044 0.262 0.2557
Schistosoma mansoni amine GPCR 0.0044 0.262 0.3332
Schistosoma mansoni muscarinic acetylcholine (GAR) receptor 0.0044 0.262 0.3332
Onchocerca volvulus 0.0019 0.0852 0.2511
Trypanosoma brucei P-type H+-ATPase, putative 0.001 0.0214 0.2543
Schistosoma mansoni notch 0.0016 0.0661 0.0758
Schistosoma mansoni biogenic amine receptor 0.0044 0.262 0.3332
Echinococcus multilocularis neurogenic locus notch protein 4 0.0016 0.0661 0.0758
Loa Loa (eye worm) hypothetical protein 0.0044 0.262 0.2557
Echinococcus multilocularis neuropeptides capa receptor 0.0044 0.262 0.3332
Plasmodium vivax calcium-transporting ATPase, putative 0.001 0.0214 0.1386
Brugia malayi Na,K-ATPase alpha subunit 0.001 0.0214 0.0184
Loa Loa (eye worm) gonadotropin-releasing hormone receptor 2 0.0044 0.262 0.2557
Echinococcus granulosus tar DNA binding protein 0.0076 0.4994 0.6452
Onchocerca volvulus Neurogenic locus notch homolog 0.0016 0.0661 0.1888
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0044 0.262 0.3332
Schistosoma mansoni hypothetical protein 0.0019 0.0852 0.1008
Loa Loa (eye worm) hypothetical protein 0.0016 0.0661 0.0582
Echinococcus granulosus g-protein coupled receptor 0.0044 0.262 0.3332
Loa Loa (eye worm) hypothetical protein 0.0044 0.262 0.2557
Echinococcus granulosus peroxidasin 0.0051 0.3141 0.4017
Loa Loa (eye worm) hypothetical protein 0.0044 0.262 0.2557
Echinococcus multilocularis dro:myosuppressin receptor 0.0044 0.262 0.3332
Schistosoma mansoni Na+/K+ transporting ATPase subunit alpha 0.001 0.0214 0.0171
Loa Loa (eye worm) hypothetical protein 0.0016 0.0661 0.0582
Loa Loa (eye worm) hypothetical protein 0.0106 0.7151 0.7127
Echinococcus multilocularis phosphoserine phosphatase 0.001 0.0214 0.0171
Brugia malayi Sodium/potassium-transporting ATPase alpha chain, putative 0.001 0.0214 0.0184
Schistosoma mansoni biogenic amine (octopamine/dopamine) receptor 0.0044 0.262 0.3332
Echinococcus granulosus thyrotropin releasing hormone receptor 0.0044 0.262 0.3332
Mycobacterium tuberculosis Probable metal cation transporter ATPase P-type CtpE 0.001 0.0214 0.1388
Echinococcus granulosus g protein coupled receptor 0.0044 0.262 0.3332
Trypanosoma brucei vacuolar-type Ca2+-ATPase 1 0.001 0.0214 0.2543
Brugia malayi neuropeptide F receptor 0.0044 0.262 0.3588
Schistosoma mansoni polycystin 1-related 0.0019 0.0852 0.1008
Trichomonas vaginalis cation-transporting ATPase, putative 0.001 0.0214 0.0875
Echinococcus granulosus cation transporting atpase worm 0.001 0.0214 0.0171
Echinococcus granulosus g protein coupled receptor 0.0044 0.262 0.3332
Brugia malayi AMP-binding enzyme family protein 0.0029 0.1543 0.2064
Loa Loa (eye worm) hypothetical protein 0.0044 0.262 0.2557
Mycobacterium leprae PROBABLE CATION-TRANSPORTER ATPASE I CTPI 0.001 0.0214 0.089
Echinococcus multilocularis neuropeptide receptor 0.0044 0.262 0.3332
Echinococcus granulosus delta-like protein 1 0.0016 0.0661 0.0758
Echinococcus multilocularis neuropeptide FF receptor 2 0.0044 0.262 0.3332
Onchocerca volvulus Peroxidasin homolog 0.0051 0.3141 1
Echinococcus granulosus growth hormone secretagogue receptor type 1 0.0044 0.262 0.3332
Echinococcus multilocularis rhodopsin orphan GPCR 0.0044 0.262 0.3332
Toxoplasma gondii haloacid dehalogenase family hydrolase domain-containing protein 0.001 0.0214 0.1642
Mycobacterium tuberculosis P-hydroxybenzoyl-AMP ligase FadD22 0.0008 0.0084 0.0546
Brugia malayi hypothetical protein 0.0051 0.3141 0.4325
Loa Loa (eye worm) hypothetical protein 0.0029 0.1543 0.1471
Loa Loa (eye worm) hypothetical protein 0.0019 0.0852 0.0774
Loa Loa (eye worm) hypothetical protein 0.0044 0.262 0.2557
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.0019 0.0875 1
Loa Loa (eye worm) hypothetical protein 0.0044 0.262 0.2557
Loa Loa (eye worm) sodium/potassium-transporting ATPase subunit alpha 0.001 0.0214 0.0131
Brugia malayi Muscle positioning protein 4 0.0016 0.0661 0.0817
Trichomonas vaginalis ATPase, class I, type 8B, putative 0.001 0.0214 0.0875
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0044 0.262 0.3332
Echinococcus granulosus neurogenic locus protein delta 0.0016 0.0661 0.0758
Loa Loa (eye worm) hypothetical protein 0.0051 0.3141 0.3082
Echinococcus granulosus rhodopsin orphan GPCR 0.0044 0.262 0.3332
Trypanosoma cruzi Calcium ATPase SERCA-like 0.001 0.0214 0.2543
Mycobacterium tuberculosis Possible fatty-acid-CoA ligase FadD1 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0008 0.0084 0.0546
Loa Loa (eye worm) hypothetical protein 0.0044 0.262 0.2557
Schistosoma mansoni hypothetical protein 0.0016 0.0661 0.0758
Loa Loa (eye worm) hypothetical protein 0.0016 0.0661 0.0582
Plasmodium falciparum LCCL domain-containing protein 0.0019 0.0852 0.6237
Onchocerca volvulus Peroxidase homolog 0.0051 0.3141 1
Echinococcus multilocularis orexin receptor type 2 0.0044 0.262 0.3332
Loa Loa (eye worm) hypothetical protein 0.0044 0.262 0.2557
Brugia malayi G-protein-linked acetylcholine receptor protein 2, putative 0.0044 0.262 0.3588
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0044 0.262 0.3332
Brugia malayi hypothetical protein 0.0044 0.262 0.3588
Entamoeba histolytica acyl-coA synthetase, putative 0.0029 0.1543 1
Echinococcus granulosus calcium transporting ATPase type 2C member 0.001 0.0214 0.0171
Loa Loa (eye worm) hypothetical protein 0.0016 0.0661 0.0582
Leishmania major 4-coumarate:coa ligase-like protein 0.0029 0.1543 1
Onchocerca volvulus 0.0044 0.262 0.8296
Trypanosoma brucei vacuolar-type Ca2+-ATPase, putative 0.001 0.0214 0.2543
Schistosoma mansoni lipoxygenase 0.0114 0.7694 1
Brugia malayi G-protein coupled receptor 0.0044 0.262 0.3588
Loa Loa (eye worm) hypothetical protein 0.0044 0.262 0.2557
Schistosoma mansoni hypothetical protein 0.0044 0.262 0.3332
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0044 0.262 0.3332
Loa Loa (eye worm) hypothetical protein 0.0044 0.262 0.2557
Loa Loa (eye worm) G-protein-linked acetylcholine receptor protein 2 0.0044 0.262 0.2557
Brugia malayi Serotonin receptor 0.0044 0.262 0.3588
Echinococcus multilocularis neuropeptide Y receptor 0.0044 0.262 0.3332
Loa Loa (eye worm) hypothetical protein 0.0029 0.1543 0.1471
Onchocerca volvulus 0.0044 0.262 0.8296
Mycobacterium ulcerans cation-transporter ATPase I CtpI 0.001 0.0214 0.089
Plasmodium vivax P-type ATPase4, putative 0.001 0.0214 0.1386
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0044 0.262 0.3332
Loa Loa (eye worm) blistered cuticle protein 3 0.0051 0.3141 0.3082
Giardia lamblia High cysteine protein 0.0016 0.0661 1
Schistosoma mansoni hypothetical protein 0.0016 0.0661 0.0758
Echinococcus granulosus neuropeptides capa receptor 0.0044 0.262 0.3332
Toxoplasma gondii P-type ATPase4, putative 0.001 0.0214 0.1642
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0044 0.262 0.3332
Schistosoma mansoni copper ABC transporter ATPase 0.001 0.0214 0.0171
Brugia malayi GCC2 and GCC3 family protein 0.0016 0.0661 0.0817
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0044 0.262 0.3332
Brugia malayi Calcium binding EGF domain containing protein 0.0016 0.0661 0.0817
Loa Loa (eye worm) hypothetical protein 0.001 0.0214 0.0131
Schistosoma mansoni biogenic amine receptor 0.0044 0.262 0.3332
Loa Loa (eye worm) animal heme peroxidase 0.0051 0.3141 0.3082
Loa Loa (eye worm) hypothetical protein 0.0106 0.7151 0.7127
Schistosoma mansoni amine GPCR 0.0044 0.262 0.3332
Brugia malayi putative neuropeptide receptor 0.0044 0.262 0.3588
Brugia malayi hypothetical protein 0.0044 0.262 0.3588
Brugia malayi RNA binding protein 0.0076 0.4994 0.6947
Echinococcus multilocularis protein jagged 1 0.0016 0.0661 0.0758
Echinococcus multilocularis tar DNA binding protein 0.0076 0.4994 0.6452
Echinococcus granulosus sex peptide receptor 0.0044 0.262 0.3332
Schistosoma mansoni opsin-like receptor 0.0044 0.262 0.3332
Onchocerca volvulus 0.0016 0.0661 0.1888
Loa Loa (eye worm) hypothetical protein 0.0044 0.262 0.2557
Onchocerca volvulus 0.0051 0.3141 1
Leishmania major ATP-dependent DEAD/H DNA helicase recQ, putative 0.0015 0.0595 0.3501
Trypanosoma cruzi ATP-dependent DEAD/H DNA helicase recQ, putative 0.0015 0.0595 1
Mycobacterium ulcerans acyl-CoA synthetase 0.0029 0.1543 1
Echinococcus multilocularis arachidonate 5 lipoxygenase 0.0114 0.7694 1
Echinococcus granulosus peptide allatostatin:somatostatin 0.0044 0.262 0.3332
Loa Loa (eye worm) hypothetical protein 0.0016 0.0661 0.0582
Echinococcus granulosus biogenic amine 5HT receptor 0.0044 0.262 0.3332
Schistosoma mansoni notch 0.0016 0.0661 0.0758
Loa Loa (eye worm) hypothetical protein 0.0044 0.262 0.2557
Toxoplasma gondii calcium-translocating P-type ATPase, PMCA-type protein 0.001 0.0214 0.1642
Loa Loa (eye worm) hypothetical protein 0.0016 0.0661 0.0582
Loa Loa (eye worm) hypothetical protein 0.0016 0.0661 0.0582
Loa Loa (eye worm) hypothetical protein 0.0044 0.262 0.2557
Echinococcus granulosus tm gpcr rhodopsin 0.0044 0.262 0.3332
Trypanosoma brucei vacuolar-type Ca2+-ATPase 2 0.001 0.0214 0.2543
Loa Loa (eye worm) follicle stimulating hormone receptor 0.0044 0.262 0.2557
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0044 0.262 0.3332
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0044 0.262 0.3332
Schistosoma mansoni amine GPCR 0.0044 0.262 0.3332
Loa Loa (eye worm) hypothetical protein 0.0044 0.262 0.2557
Entamoeba histolytica Plasma membrane calcium-transporting ATPase, putative 0.001 0.0214 0.089
Echinococcus multilocularis rhodopsin orphan GPCR 0.0044 0.262 0.3332
Brugia malayi Cadherin domain containing protein 0.0016 0.0661 0.0817
Brugia malayi Probable cation-transporting ATPase C10C6.6 in chromosome IV 0.001 0.0214 0.0184

Activities

Activity type Activity value Assay description Source Reference
Potency (functional) 7.9433 uM PubChem BioAssay. qHTS for Inhibitors of WRN Helicase. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) 9.285 uM PUBCHEM_BIOASSAY: Primary qHTS for delayed death inhibitors of the malarial parasite plastid, 48 hour incubation. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID488752, AID488774, AID504848, AID504850] ChEMBL. No reference
Potency (functional) 13.4591 uM PUBCHEM_BIOASSAY: qHTS profiling assay for firefly luciferase inhibitor/activator using purified enzyme and Km concentrations of substrates (counterscreen for miR-21 project). (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID2288, AID2289, AID2598, AID411] ChEMBL. No reference
Potency (functional) 14.1254 uM PubChem BioAssay. qHTS of TDP-43 Inhibitors. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) 16.9469 uM PubChem BioAssay. qHTS for Inhibitors of the Phosphatase Activity of Eya2: Confirmatory Assay for Cherry-picked Compounds. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) 29.0929 uM PUBCHEM_BIOASSAY: Nrf2 qHTS screen for inhibitors. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID493153, AID493163, AID504648] ChEMBL. No reference
Potency (functional) 32.6427 uM PubChem BioAssay. A quantitative high throughput screen for small molecules that induce DNA re-replication in MCF 10a normal breast cells. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) = 35.4813 um PUBCHEM_BIOASSAY: qHTS Assay for Inhibitors of Human Jumonji Domain Containing 2E (JMJD2E). (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) 44.6684 uM PubChem BioAssay. qHTS of PTHR Inhibitors: Primary Screen. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) 44.6684 uM PubChem BioAssay. qHTS for Antagonists of gsp, the Etiologic Mutation Responsible for Fibrous Dysplasia/McCune-Albright Syndrome: qHTS. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) 84.9214 uM PubChem BioAssay. qHTS Assay to Find Inhibitors of Pin1. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) 89.1251 uM PUBCHEM_BIOASSAY: qHTS for Inhibitors of Polymerase Iota. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID588623] ChEMBL. No reference

Phenotypes

Whole-cell/tissue/organism interactions

Species name Source Reference Is orphan
Plasmodium falciparum ChEMBL23

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

Bibliographic References

No literature references available for this target.

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