Detailed information for compound 1340868

Basic information

Technical information
  • TDR Targets ID: 1340868
  • Name: N-(3,5-dimethylphenyl)-4-(4-hydroxy-3-methoxy phenyl)-6-methyl-2-oxo-3,4-dihydro-1H-pyrimid ine-5-carboxamide
  • MW: 381.425 | Formula: C21H23N3O4
  • H donors: 4 H acceptors: 3 LogP: 2.34 Rotable bonds: 5
    Rule of 5 violations (Lipinski): 1
  • SMILES: COc1cc(ccc1O)C1NC(=O)NC(=C1C(=O)Nc1cc(C)cc(c1)C)C
  • InChi: 1S/C21H23N3O4/c1-11-7-12(2)9-15(8-11)23-20(26)18-13(3)22-21(27)24-19(18)14-5-6-16(25)17(10-14)28-4/h5-10,19,25H,1-4H3,(H,23,26)(H2,22,24,27)
  • InChiKey: QSZNBWGPKFIKFF-UHFFFAOYSA-N  


Substructure search Similarity search

Network

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Synonyms

  • N-(3,5-dimethylphenyl)-4-(4-hydroxy-3-methoxy-phenyl)-6-methyl-2-oxo-3,4-dihydro-1H-pyrimidine-5-carboxamide
  • N-(3,5-dimethylphenyl)-4-(4-hydroxy-3-methoxy-phenyl)-2-keto-6-methyl-3,4-dihydro-1H-pyrimidine-5-carboxamide
  • BAS 07396410
  • EU-0080932
  • Oprea1_539445
  • NCGC00100296-01
  • Oprea1_138168
  • STOCK3S-54696

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Loa Loa (eye worm) hypothetical protein 0.0035 0.0146 0.0146
Trichomonas vaginalis Clan MG, familly M24, aminopeptidase P-like metallopeptidase 0.0043 0.0219 0.0433
Brugia malayi excitatory GABA receptor EXP-1A 0.0019 0.0009 0.0001
Mycobacterium tuberculosis Probable NADH dehydrogenase Ndh 0.0084 0.056 0.0792
Echinococcus multilocularis neuropeptide s receptor 0.0453 0.3688 0.5442
Onchocerca volvulus 0.0063 0.0381 0.0372
Echinococcus multilocularis nuclear receptor subfamily 1 group D 0.0033 0.0131 0.018
Trypanosoma brucei protein farnesyltransferase beta subunit 0.002 0.0022 0.0024
Treponema pallidum ATP-dependent Clp protease proteolytic subunit 0.0077 0.0507 1
Onchocerca volvulus Phospholipase A2 homolog 0.1197 1 1
Toxoplasma gondii 3-oxo-5-alpha-steroid 4-dehydrogenase 0.032 0.2562 0.5182
Schistosoma mansoni integrin beta subunit 0.0179 0.1368 0.5325
Trichomonas vaginalis protein farnesyltransferase beta subunit, putative 0.002 0.0022 0.0033
Echinococcus granulosus integrin beta 2 0.0225 0.176 0.476
Loa Loa (eye worm) hypothetical protein 0.003 0.0101 0.0101
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.002 0.0018 0.0009
Brugia malayi Nuclear hormone receptor family member nhr-31 0.0063 0.0381 0.0373
Loa Loa (eye worm) hypothetical protein 0.0169 0.128 0.128
Loa Loa (eye worm) pigment dispersing factor receptor c 0.005 0.0275 0.0275
Trichomonas vaginalis short-chain dehydrogenase, putative 0.002 0.0018 0.0025
Loa Loa (eye worm) hypothetical protein 0.0231 0.181 0.181
Trypanosoma brucei beta-ketoacyl-ACP reductase 2 0.002 0.0018 0.0016
Toxoplasma gondii 3-oxo-5-alpha-steroid 4-dehydrogenase 0.032 0.2562 0.5182
Loa Loa (eye worm) hypothetical protein 0.0142 0.1055 0.1055
Trichomonas vaginalis geranylgeranyl transferase type II beta subunit, putative 0.002 0.0022 0.0033
Brugia malayi hypothetical protein 0.0025 0.0062 0.0053
Echinococcus granulosus thioredoxin glutathione reductase 0.0037 0.0165 0.0426
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.0063 0.0381 0.1013
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0035 0.0146 0.0146
Wolbachia endosymbiont of Brugia malayi ATP-dependent Clp protease proteolytic subunit 0.0077 0.0507 1
Schistosoma mansoni hypothetical protein 0.0066 0.0407 0.1559
Schistosoma mansoni family S9 non-peptidase homologue (S09 family) 0.0023 0.0048 0.0152
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0019 0.0009 0.0001
Entamoeba histolytica protein farnesyltransferase beta subunit, putative 0.002 0.0022 0.0027
Toxoplasma gondii Rab geranylgeranyl transferase type II beta subunit, putative 0.002 0.0022 0.0027
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0036 0.0155 0.0251
Trichomonas vaginalis short-chain dehydrogenase, putative 0.002 0.0018 0.0025
Echinococcus granulosus RNA directed DNA polymerase 0.0086 0.0583 0.156
Echinococcus granulosus glycine receptor subunit alpha 1 0.0019 0.0009 0.0002
Mycobacterium leprae PROBABLE ATP-DEPENDENT CLP PROTEASE PROTEOLYTIC SUBUNIT 1 CLPP1 (ENDOPEPTIDASE CLP) 0.0051 0.028 0.1796
Schistosoma mansoni family M13 unassigned peptidase (M13 family) 0.0097 0.0673 0.26
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.002 0.0018 0.0009
Echinococcus granulosus protein kinase C gamma type 0.0108 0.0765 0.2055
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.0063 0.0381 0.1459
Schistosoma mansoni synaptic glycoprotein sc2 related 0.032 0.2562 1
Brugia malayi Nuclear hormone receptor family member nhr-3 0.0063 0.0381 0.0373
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.0063 0.0381 0.0381
Brugia malayi hypothetical protein 0.002 0.0018 0.0009
Schistosoma mansoni hypothetical protein 0.0034 0.0141 0.0517
Onchocerca volvulus 0.0667 0.5503 0.5499
Loa Loa (eye worm) MH2 domain-containing protein 0.0236 0.1852 0.1852
Echinococcus granulosus carbonyl reductase 1 0.002 0.0018 0.0024
Echinococcus multilocularis neuroligin 0.0023 0.0048 0.0058
Echinococcus granulosus aldehyde dehydrogenase mitochondrial 0.0061 0.0366 0.0971
Trypanosoma cruzi cysteine peptidase, clan CA, family C1, cathepsin L-like, putative 0.0057 0.0332 0.0573
Schistosoma mansoni hypothetical protein 0.005 0.0275 0.1045
Echinococcus granulosus nuclear receptor subfamily 1 group D 0.0033 0.0131 0.0331
Trypanosoma brucei sterol 24-c-methyltransferase, putative 0.0106 0.0749 0.1346
Loa Loa (eye worm) hypothetical protein 0.002 0.0022 0.0022
Echinococcus granulosus nicotinic acetylcholine receptor beta 1 subunit 0.0019 0.0009 0.0002
Toxoplasma gondii 3-ketoacyl-CoA reductase, putative 0.002 0.0018 0.0018
Echinococcus granulosus Dehydrogenase:reductase SDR family 0.002 0.0018 0.0024
Echinococcus multilocularis neuropeptide receptor A26 0.0453 0.3688 0.5442
Trichomonas vaginalis esterase, putative 0.0035 0.0146 0.0286
Toxoplasma gondii 3-oxo-5-alpha-steroid 4-dehydrogenase 0.06 0.4937 1
Chlamydia trachomatis ATP-dependent Clp protease proteolytic subunit 0.0077 0.0507 0.5
Loa Loa (eye worm) AGC/PKC/ALPHA protein kinase 0.009 0.0609 0.0609
Loa Loa (eye worm) hypothetical protein 0.032 0.2562 0.2562
Trypanosoma brucei inositol-1(or 4)-monophosphatase 1, putative 0.0036 0.0155 0.0267
Onchocerca volvulus 0.002 0.0018 0.0008
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.002 0.0018 0.0009
Brugia malayi Neurotransmitter-gated ion-channel transmembrane region family protein 0.0019 0.0009 0.0001
Onchocerca volvulus 0.0028 0.009 0.008
Brugia malayi aspartic protease BmAsp-1, identical 0.0028 0.009 0.0081
Onchocerca volvulus 0.0064 0.0391 0.0382
Schistosoma mansoni cathepsin D (A01 family) 0.0212 0.1647 0.6416
Echinococcus granulosus acetylcholinesterase 0.0138 0.1021 0.275
Loa Loa (eye worm) hypothetical protein 0.003 0.0101 0.0101
Trichomonas vaginalis penicillin-binding protein, putative 0.0035 0.0146 0.0286
Loa Loa (eye worm) TAR-binding protein 0.0062 0.0374 0.0374
Echinococcus multilocularis retinoic acid receptor rxr beta a retinoic acid receptor rxr alpha a retinoic acid receptor rxr alpha 0.003 0.0101 0.0136
Onchocerca volvulus Dehydrogenase\/reductase SDR family member 1 homolog 0.002 0.0018 0.0008
Loa Loa (eye worm) prenyltransferase and squalene oxidase repeat family protein 0.002 0.0022 0.0022
Brugia malayi nuclear receptor NHR-88 0.003 0.0101 0.0092
Schistosoma mansoni family M13 unassigned peptidase (M13 family) 0.0047 0.0247 0.0933
Loa Loa (eye worm) nuclear hormone receptor-like 1 0.0033 0.0131 0.0131
Plasmodium falciparum geranylgeranyl transferase type2 beta subunit, putative 0.002 0.0022 0.0017
Brugia malayi hypothetical protein 0.0023 0.0048 0.0039
Toxoplasma gondii carbonyl reductase 1, putative 0.002 0.0018 0.0018
Echinococcus multilocularis peptidase Clp (S14 family) 0.0051 0.028 0.0402
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0063 0.0381 0.0373
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0028 0.009 0.0316
Brugia malayi RNA recognition motif domain containing protein 0.0062 0.0374 0.0365
Toxoplasma gondii aspartyl protease ASP3 0.0028 0.009 0.0164
Mycobacterium ulcerans aldehyde dehydrogenase 0.0061 0.0366 0.0508
Onchocerca volvulus 0.002 0.0018 0.0008
Leishmania major 3-oxo-5-alpha-steroid 4-dehydrogenase-like protein 0.06 0.4937 0.8967
Loa Loa (eye worm) AGC/PKC/ETA protein kinase 0.0035 0.0144 0.0144
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.002 0.0018 0.0009
Echinococcus granulosus methionyl aminopeptidase 2 0.0043 0.0219 0.0571
Plasmodium falciparum glutathione reductase 0.0037 0.0161 0.0565
Loa Loa (eye worm) hypothetical protein 0.0145 0.1083 0.1083
Loa Loa (eye worm) hypothetical protein 0.0035 0.0146 0.0146
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.006 0.0357 0.0947
Echinococcus granulosus nuclear receptor 2DBD gamma 0.003 0.0101 0.025
Trichomonas vaginalis carboxylesterase domain containing protein, putative 0.0023 0.0048 0.0086
Loa Loa (eye worm) hypothetical protein 0.0138 0.1021 0.1021
Echinococcus granulosus tar DNA binding protein 0.0062 0.0374 0.0992
Echinococcus multilocularis Nuclear hormone receptor HR96 0.003 0.0101 0.0136
Schistosoma mansoni short chain dehydrogenase 0.002 0.0018 0.0034
Loa Loa (eye worm) hypothetical protein 0.0028 0.009 0.009
Schistosoma mansoni short chain dehydrogenase 0.002 0.0018 0.0034
Brugia malayi hypothetical protein 0.002 0.0018 0.0009
Loa Loa (eye worm) AGC/PKN protein kinase 0.0019 0.0009 0.0009
Trichomonas vaginalis 3-oxo-5-alpha-steroid 4-dehydrogenase, putative 0.06 0.4937 1
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.002 0.0018 0.0009
Brugia malayi Synaptic glycoprotein SC2 0.032 0.2562 0.2556
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0062 0.0378 0.0671
Brugia malayi Prenyltransferase and squalene oxidase repeat family protein 0.002 0.0022 0.0013
Schistosoma mansoni family M13 unassigned peptidase (M13 family) 0.0047 0.0247 0.0933
Brugia malayi Thioredoxin reductase 0.0037 0.0161 0.0153
Schistosoma mansoni oxidoreductase short chain dehydrogenase/reductase family 0.002 0.0018 0.0034
Loa Loa (eye worm) oxidoreductase 0.002 0.0018 0.0018
Schistosoma mansoni steroid dehydrogenase 0.002 0.0018 0.0034
Echinococcus multilocularis serine threonine protein kinase 0.0108 0.0765 0.1118
Entamoeba histolytica hypothetical protein, conserved 0.002 0.0018 0.0018
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0179 0.1364 0.5306
Mycobacterium tuberculosis Probable zinc metalloprotease Zmp1 0.0192 0.1481 0.2135
Echinococcus granulosus neuropeptide receptor A26 0.0453 0.3688 1
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.0063 0.0381 0.1013
Schistosoma mansoni geranylgeranyl transferase type II beta subunit 0.002 0.0022 0.0051
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0028 0.009 0.0316
Loa Loa (eye worm) kelch domain-containing protein family protein 0.0046 0.0242 0.0242
Schistosoma mansoni BC026374 protein (S09 family) 0.0023 0.0048 0.0152
Schistosoma mansoni nuclear receptor 0.003 0.0101 0.036
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.003 0.0101 0.0091
Loa Loa (eye worm) hypothetical protein 0.0228 0.1787 0.1787
Plasmodium falciparum ataxin-2 like protein, putative 0.0025 0.0062 0.0173
Echinococcus multilocularis carboxylesterase 5A 0.0138 0.1021 0.1496
Brugia malayi nuclear receptor subfamily 1, group D, member 1, putative 0.003 0.0101 0.0092
Loa Loa (eye worm) PHD-finger family protein 0.0021 0.0025 0.0025
Echinococcus multilocularis methionyl aminopeptidase 2 0.0043 0.0219 0.0311
Loa Loa (eye worm) hypothetical protein 0.0033 0.0131 0.0131
Toxoplasma gondii oxidoreductase, short chain dehydrogenase/reductase family protein 0.002 0.0018 0.0018
Schistosoma mansoni Cys-loop ligand gated ion channel subunit 0.0019 0.0009 0.0003
Loa Loa (eye worm) hypothetical protein 0.0145 0.1083 0.1083
Onchocerca volvulus 0.002 0.0018 0.0008
Schistosoma mansoni short chain dehydrogenase 0.002 0.0018 0.0034
Trichomonas vaginalis short-chain dehydrogenase, putative 0.002 0.0018 0.0025
Schistosoma mansoni 3-keto-dihydrosphingosine reductase 0.002 0.0018 0.0034
Trypanosoma brucei methionine aminopeptidase 2, putative 0.0043 0.0219 0.0382
Loa Loa (eye worm) hypothetical protein 0.0035 0.0146 0.0146
Loa Loa (eye worm) hypothetical protein 0.003 0.0101 0.0101
Plasmodium vivax ATP-dependent Clp protease proteolytic subunit, putative 0.0077 0.0507 0.1922
Plasmodium vivax aspartyl protease, putative 0.0028 0.009 0.0283
Loa Loa (eye worm) aspartic protease BmAsp-1 0.0028 0.009 0.009
Onchocerca volvulus 0.0667 0.5503 0.5499
Schistosoma mansoni short chain dehydrogenase 0.002 0.0018 0.0034
Brugia malayi Bromodomain containing protein 0.0038 0.0175 0.0167
Mycobacterium tuberculosis Probable reductase 0.0084 0.056 0.0792
Trichomonas vaginalis AGC family protein kinase 0.0019 0.0009 0.0007
Schistosoma mansoni 3-hydroxyacyl-CoA dehydrogenase 0.002 0.0018 0.0034
Echinococcus granulosus 3 ketodihydrosphingosine reductase 0.002 0.0018 0.0024
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0062 0.0378 0.0671
Echinococcus multilocularis acetylcholinesterase 0.0138 0.1021 0.1496
Echinococcus granulosus protein kinase c iota type 0.0032 0.0121 0.0305
Echinococcus granulosus protein kinase c epsilon type 0.0035 0.0144 0.0369
Loa Loa (eye worm) hypothetical protein 0.0368 0.2973 0.2973
Brugia malayi hypothetical protein 0.003 0.0101 0.0092
Schistosoma mansoni Cys-loop ligand gated ion channel subunit 0.0019 0.0009 0.0003
Trypanosoma brucei 3-oxo-5-alpha-steroid 4-dehydrogenase-like, putative 0.06 0.4937 0.8968
Schistosoma mansoni methionyl aminopeptidase 2 (M24 family) 0.0043 0.0219 0.0822
Echinococcus granulosus protein farnesyltransferase subunit beta 0.002 0.0022 0.0036
Loa Loa (eye worm) hypothetical protein 0.0099 0.069 0.069
Trichomonas vaginalis short-chain dehydrogenase, putative 0.002 0.0018 0.0025
Loa Loa (eye worm) hypothetical protein 0.0019 0.0009 0.0009
Toxoplasma gondii ATP-dependent Clp endopeptidase, proteolytic subunit ClpP domain-containing protein 0.0077 0.0507 0.101
Trichomonas vaginalis synaptic glycoprotein sc2, putative 0.032 0.2562 0.5185
Loa Loa (eye worm) dehydrogenase 0.002 0.0018 0.0018
Schistosoma mansoni tar DNA-binding protein 0.0062 0.0374 0.143
Echinococcus granulosus BC026374 protein S09 family 0.0023 0.0048 0.0106
Onchocerca volvulus Dehydrogenase\/reductase SDR family member 13 homolog 0.002 0.0018 0.0008
Entamoeba histolytica hypothetical protein 0.032 0.2562 0.5182
Leishmania major lanosterol synthase, putative 0.0128 0.0934 0.1671
Mycobacterium tuberculosis Halimadienyl diphosphate synthase 0.0082 0.0545 0.077
Brugia malayi S-adenosyl-methionine cycloartenol-C24-methyltransferase 0.0099 0.069 0.0681
Leishmania major cathepsin L-like protease 0.0062 0.0378 0.0656
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.0063 0.0381 0.1459
Loa Loa (eye worm) AGC/NDR protein kinase 0.0019 0.0009 0.0009
Loa Loa (eye worm) hypothetical protein 0.002 0.0018 0.0018
Schistosoma mansoni steroid dehydrogenase 0.002 0.0018 0.0034
Mycobacterium leprae Probable lipase LipE 0.0035 0.0146 0.088
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.002 0.0018 0.0009
Trichomonas vaginalis hydroxyacyl dehydrogenase, putative 0.002 0.0018 0.0025
Schistosoma mansoni atypical protein kinase C 0.0032 0.0121 0.044
Plasmodium falciparum plasmepsin II 0.012 0.0864 0.3325
Loa Loa (eye worm) hypothetical protein 0.002 0.0018 0.0018
Echinococcus granulosus carbonyl reductase 1 0.002 0.0018 0.0024
Echinococcus multilocularis nuclear receptor subfamily 4 group A 0.003 0.0101 0.0136
Loa Loa (eye worm) hypothetical protein 0.0033 0.0131 0.0131
Entamoeba histolytica oxidoreductase, short chain dehydrogenase/reductase family 0.002 0.0018 0.0018
Mycobacterium leprae PROBABLE NADH DEHYDROGENASE NDH 0.0084 0.056 0.371
Mycobacterium tuberculosis Probable oxidoreductase 0.0093 0.064 0.0908
Echinococcus granulosus nuclear receptor nhr 48 0.003 0.0101 0.025
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.003 0.0101 0.0136
Loa Loa (eye worm) hypothetical protein 0.0145 0.1083 0.1083
Brugia malayi Nuclear hormone receptor family member nhr-40 0.0063 0.0381 0.0373
Echinococcus multilocularis nuclear receptor nhr 48 0.003 0.0101 0.0136
Schistosoma mansoni peptidase Clp (S14 family) 0.0077 0.0507 0.195
Echinococcus granulosus inositol monophosphatase 1 0.0036 0.0155 0.0399
Schistosoma mansoni carbonyl reductase 0.002 0.0018 0.0034
Brugia malayi Neurotransmitter-gated ion-channel transmembrane region family protein 0.0019 0.0009 0.0001
Mycobacterium tuberculosis POSSIBLE PARA-NITROBENZYL ESTERASE (FRAGMENT) 0.0023 0.0048 0.0044
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0036 0.0155 0.0304
Echinococcus granulosus neuropeptide s receptor 0.0453 0.3688 1
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0062 0.0378 0.0671
Onchocerca volvulus 0.003 0.0101 0.0091
Schistosoma mansoni retinoic acid receptor RXR 0.0063 0.0381 0.1459
Loa Loa (eye worm) steroid hormone receptor 0.0063 0.0381 0.0381
Echinococcus granulosus nicotinic acetylcholine receptor subunit type 0.0019 0.0009 0.0002
Toxoplasma gondii ATP-dependent Clp endopeptidase, proteolytic subunit ClpP domain-containing protein 0.0077 0.0507 0.101
Trichomonas vaginalis 3-oxo-5-alpha-steroid 4-dehydrogenase, putative 0.032 0.2562 0.5185
Loa Loa (eye worm) AGC/DMPK/GEK protein kinase 0.0019 0.0009 0.0009
Schistosoma mansoni thyroid hormone receptor 0.0063 0.0381 0.1459
Echinococcus granulosus integrin alpha ps 0.0066 0.0407 0.1082
Toxoplasma gondii 2,4-dienoyl CoA reductase 2, peroxisomal family protein 0.002 0.0018 0.0018
Mycobacterium tuberculosis POSSIBLE PARA-NITROBENZYL ESTERASE (FRAGMENT) 0.0023 0.0048 0.0044
Schistosoma mansoni inositol monophosphatase 0.0036 0.0155 0.0574
Loa Loa (eye worm) hypothetical protein 0.0048 0.0259 0.0259
Brugia malayi nuclear receptor NHR-67 0.003 0.0101 0.0092
Toxoplasma gondii sterol carrier protein-2 HAD-2SCP-2 0.002 0.0018 0.0018
Loa Loa (eye worm) hypothetical protein 0.0019 0.0009 0.0009
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.0063 0.0381 0.0381
Loa Loa (eye worm) inositol-1 0.0036 0.0155 0.0155
Schistosoma mansoni neprilysin 0.005 0.0275 0.1045
Trypanosoma cruzi cysteine peptidase, putative 0.0062 0.0378 0.0656
Brugia malayi Cation transporter family protein 0.0019 0.0009 0.0001
Trichomonas vaginalis geranylgeranyl transferase type beta subunit, putative 0.002 0.0022 0.0033
Brugia malayi nicotinic acetylcholine receptor alpha subunit, putative 0.0019 0.0009 0.0001
Brugia malayi Steroid receptor seven-up type 2 0.0063 0.0381 0.0373
Loa Loa (eye worm) hypothetical protein 0.0064 0.0391 0.0391
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0062 0.0378 0.0671
Schistosoma mansoni short chain dehydrogenase 0.002 0.0018 0.0034
Trypanosoma brucei metallo-peptidase, Clan MG, Family M24 0.0043 0.0219 0.0382
Mycobacterium tuberculosis Conserved protein 0.0035 0.0146 0.0188
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0062 0.0378 0.0671
Brugia malayi nuclear hormone receptor family member odr-7 0.003 0.0101 0.0092
Loa Loa (eye worm) hypothetical protein 0.0019 0.0009 0.0009
Loa Loa (eye worm) hypothetical protein 0.06 0.4937 0.4937
Loa Loa (eye worm) hypothetical protein 0.0041 0.0196 0.0196
Loa Loa (eye worm) acetylcholine receptor alpha subunit 0.0019 0.0009 0.0009
Echinococcus granulosus Cys loop ligand gated ion channel subunit 0.0019 0.0009 0.0002
Plasmodium falciparum ATP-dependent Clp protease proteolytic subunit 0.0027 0.0076 0.023
Loa Loa (eye worm) platelet-activating factor acetylhydrolase 0.0667 0.5503 0.5503
Plasmodium vivax hypothetical protein, conserved 0.0035 0.0146 0.0506
Brugia malayi dehydrogenases, short chain protein 2 0.002 0.0018 0.0009
Toxoplasma gondii hypothetical protein 0.0027 0.0076 0.0137
Brugia malayi Calcitonin receptor-like protein seb-1 0.005 0.0275 0.0267
Echinococcus granulosus carboxylesterase 5A 0.0138 0.1021 0.275
Plasmodium vivax plasmepsin IV, putative 0.012 0.0864 0.3325
Loa Loa (eye worm) hypothetical protein 0.003 0.0101 0.0101
Onchocerca volvulus 0.032 0.2562 0.2555
Brugia malayi photoreceptor-specific nuclear receptor 0.0063 0.0381 0.0373
Plasmodium falciparum protein farnesyltransferase subunit beta 0.002 0.0022 0.0017
Echinococcus multilocularis atpase aaa+ type core atpase aaa type core 0.0816 0.677 1
Schistosoma mansoni short chain dehydrogenase 0.002 0.0018 0.0034
Echinococcus granulosus fetal alzheimer antigen falz 0.0023 0.0041 0.0089
Loa Loa (eye worm) oxidoreductase 0.002 0.0018 0.0018
Loa Loa (eye worm) hypothetical protein 0.0019 0.0009 0.0009
Mycobacterium ulcerans short chain dehydrogenase 0.0828 0.687 1
Trypanosoma cruzi sterol 24-c-methyltransferase, putative 0.0203 0.1573 0.2836
Trypanosoma brucei 3-keto-dihydrosphingosine reductase 0.002 0.0018 0.0016
Echinococcus multilocularis integrin beta 2 0.0225 0.176 0.259
Trypanosoma brucei geranylgeranyl transferase type II beta subunit, putative 0.002 0.0022 0.0024
Trypanosoma brucei beta-ketoacyl-ACP reductase 3, putative 0.002 0.0018 0.0016
Schistosoma mansoni family S9 non-peptidase homologue (S09 family) 0.0023 0.0048 0.0152
Trypanosoma brucei 3-oxo-5-alpha-steroid 4-dehydrogenase, putative 0.032 0.2562 0.4647
Entamoeba histolytica steroid 5-alpha reductase, putative 0.06 0.4937 1
Loa Loa (eye worm) hypothetical protein 0.0019 0.0009 0.0009
Brugia malayi Hypothetical zinc metalloproteinase T16A9.4 0.0192 0.1481 0.1473
Trypanosoma brucei short-chain dehydrogenase, putative 0.002 0.0018 0.0016
Loa Loa (eye worm) ACC-1 protein 0.0019 0.0009 0.0009
Echinococcus multilocularis retinol dehydrogenase 11 0.002 0.0018 0.0013
Loa Loa (eye worm) hypothetical protein 0.0028 0.009 0.009
Schistosoma mansoni steroid dehydrogenase 0.002 0.0018 0.0034
Schistosoma mansoni nAChR subunit 0.0019 0.0009 0.0003
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0062 0.0378 0.0671
Echinococcus granulosus 3 oxo 5 alpha steroid 4 dehydrogenase C terminal 0.032 0.2562 0.694
Loa Loa (eye worm) hypothetical protein 0.0071 0.0455 0.0455
Echinococcus granulosus integrin alpha ps 0.0137 0.1012 0.2726
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.002 0.0018 0.0009
Loa Loa (eye worm) hypothetical protein 0.003 0.0101 0.0101
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0062 0.0378 0.0671
Brugia malayi hypothetical protein 0.0028 0.009 0.0081
Loa Loa (eye worm) carboxylesterase 0.0138 0.1021 0.1021
Loa Loa (eye worm) hypothetical protein 0.0019 0.0009 0.0009
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0179 0.1364 0.5306
Toxoplasma gondii aspartyl proteinase (eimepsin), putative 0.012 0.0864 0.1735
Trypanosoma brucei short-chain dehydrogenase, putative 0.002 0.0018 0.0016
Loa Loa (eye worm) hypothetical protein 0.0033 0.0131 0.0131
Onchocerca volvulus 0.0023 0.0048 0.0038
Echinococcus multilocularis integrin alpha 3 0.0234 0.1837 0.2703
Brugia malayi Eukaryotic aspartyl protease family protein 0.0028 0.009 0.0081
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0028 0.009 0.0316
Brugia malayi beta-lactamase family protein 0.0035 0.0146 0.0138
Brugia malayi gamma-aminobutyric-acid receptor beta subunit precursor 0.0019 0.0009 0.0001
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.0036 0.0155 0.0398
Echinococcus multilocularis integrin alpha ps 0.0137 0.1012 0.1483
Schistosoma mansoni short chain dehydrogenase 0.002 0.0018 0.0034
Trypanosoma cruzi hypothetical protein, conserved 0.0035 0.0146 0.0235
Trichomonas vaginalis estradiol 17 beta-dehydrogenase, putative 0.002 0.0018 0.0025
Loa Loa (eye worm) hypothetical protein 0.0071 0.0451 0.0451
Brugia malayi Retinol dehydrogenase 12 0.002 0.0018 0.0009
Brugia malayi Carboxylesterase family protein 0.0023 0.0048 0.0039
Mycobacterium tuberculosis Probable membrane NADH dehydrogenase NdhA 0.0084 0.056 0.0792
Loa Loa (eye worm) hypothetical protein 0.0095 0.0658 0.0658
Entamoeba histolytica short chain dehydrogenase family protein 0.002 0.0018 0.0018
Loa Loa (eye worm) nuclear hormone receptor 0.003 0.0101 0.0101
Brugia malayi Nuclear hormone receptor family member nhr-49 0.0063 0.0381 0.0373
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.0063 0.0381 0.0551
Echinococcus multilocularis retinol dehydrogenase 13 0.002 0.0018 0.0013
Loa Loa (eye worm) ligand-Gated ion Channel family member 0.0019 0.0009 0.0009
Schistosoma mansoni nuclear hormone receptor superfamily protein-related 0.003 0.0101 0.036
Mycobacterium ulcerans esterase/lipase LipP 0.0035 0.0146 0.0188
Loa Loa (eye worm) hypothetical protein 0.0034 0.0141 0.0141
Loa Loa (eye worm) hypothetical protein 0.0046 0.0242 0.0242
Loa Loa (eye worm) hypothetical protein 0.002 0.0018 0.0018
Loa Loa (eye worm) hypothetical protein 0.0019 0.0009 0.0009
Trypanosoma cruzi trypanothione reductase, putative 0.0037 0.0161 0.0262
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0179 0.1364 0.1364
Leishmania major methionine aminopeptidase 2, putative 0.0043 0.0219 0.0367
Echinococcus granulosus family S9 non peptidase ue S09 family 0.0023 0.0048 0.0106
Schistosoma mansoni integrin alpha-ps 0.0137 0.1012 0.3928
Brugia malayi conserved hypotetical protein 0.003 0.0101 0.0092
Mycobacterium tuberculosis Probable lipase LipD 0.0035 0.0146 0.0188
Onchocerca volvulus 0.0028 0.009 0.008
Echinococcus granulosus survival motor neuron protein 1 0.0228 0.1787 0.4833
Echinococcus granulosus tumor protein p63 0.033 0.2645 0.7164
Plasmodium vivax glutathione reductase, putative 0.0037 0.0161 0.0565
Trypanosoma brucei oxidoreductase-like protein 0.002 0.0018 0.0016
Leishmania major sterol 24-c-methyltransferase, putative 0.0203 0.1573 0.2836
Loa Loa (eye worm) carboxylesterase 0.0023 0.0048 0.0048
Trypanosoma cruzi PAB1-binding protein , putative 0.0025 0.0062 0.008
Giardia lamblia Synaptic glycoprotein SC2 0.032 0.2562 1
Loa Loa (eye worm) glutamate-gated chloride channel alpha3A subunit 0.0019 0.0009 0.0009
Echinococcus granulosus nAChR subunit 0.0019 0.0009 0.0002
Brugia malayi Carboxylesterase family protein 0.0138 0.1021 0.1013
Schistosoma mansoni coup transcription factor 0.0063 0.0381 0.1459
Echinococcus granulosus beta LACTamase domain containing family member 0.0035 0.0146 0.0374
Onchocerca volvulus 0.002 0.0018 0.0008
Loa Loa (eye worm) aspartyl protease 6 0.0028 0.009 0.009
Echinococcus multilocularis FTZ F1 alpha 0.0063 0.0381 0.0551
Schistosoma mansoni protein farnesyltransferase subunit beta 0.002 0.0022 0.0051
Plasmodium falciparum plasmepsin VII 0.0028 0.009 0.0283
Schistosoma mansoni Tr4/Tr2 (homologue) 0.0063 0.0381 0.1459
Schistosoma mansoni nAChR subunit (ShAR1-alpha-like) 0.0019 0.0009 0.0003
Loa Loa (eye worm) transcription factor SMAD2 0.0236 0.1852 0.1852
Trichomonas vaginalis AGC family protein kinase 0.0019 0.0009 0.0007
Plasmodium vivax thioredoxin reductase, putative 0.0037 0.0161 0.0565
Trypanosoma brucei 3-ketoacyl-CoA reductase, putative 0.002 0.0018 0.0016
Trypanosoma cruzi cysteine peptidase, putative 0.0062 0.0378 0.0656
Onchocerca volvulus 0.002 0.0018 0.0008
Trichomonas vaginalis short-chain dehydrogenase, putative 0.002 0.0018 0.0025
Plasmodium falciparum methionine aminopeptidase 2 0.0043 0.0219 0.0791
Brugia malayi MH2 domain containing protein 0.0236 0.1852 0.1845
Mycobacterium leprae ATP-dependent Clp protease proteolytic subunit 1 0.0027 0.0076 0.0401
Echinococcus granulosus neuroligin 0.0023 0.0048 0.0106
Trichomonas vaginalis synaptic glycoprotein sc2, putative 0.032 0.2562 0.5185
Schistosoma mansoni short chain dehydrogenase 0.002 0.0018 0.0034
Trypanosoma brucei hypothetical protein, conserved 0.0035 0.0146 0.025
Plasmodium vivax ATP-dependent Clp protease proteolytic subunit, putative 0.0027 0.0076 0.023
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.012 0.0864 0.3347
Entamoeba histolytica Rab geranylgeranyltransferase beta subunit, putative 0.002 0.0022 0.0027
Leishmania major farnesyltransferase beta subunit 0.002 0.0022 0.0008
Mycobacterium tuberculosis Conserved protein 0.0035 0.0146 0.0188
Onchocerca volvulus 0.002 0.0018 0.0008
Echinococcus granulosus ATP dependent Clp protease proteolytic subunit 0.0077 0.0507 0.1353
Schistosoma mansoni memapsin-2 (A01 family) 0.0028 0.009 0.0316
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.0036 0.0155 0.0217
Loa Loa (eye worm) LGC-31 protein 0.0019 0.0009 0.0009
Trypanosoma brucei short-chain dehydrogenase, putative 0.002 0.0018 0.0016
Echinococcus multilocularis aldehyde dehydrogenase, mitochondrial 0.0061 0.0366 0.0528
Echinococcus granulosus 3 hydroxyacyl coenzyme A dehydrogenase type 2 0.002 0.0018 0.0024
Schistosoma mansoni steroid dehydrogenase 0.002 0.0018 0.0034
Trichomonas vaginalis synaptic glycoprotein sc2, putative 0.032 0.2562 0.5185
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0063 0.0381 0.1013
Echinococcus multilocularis 3 oxo 5 alpha steroid 4 dehydrogenase, C terminal 0.032 0.2562 0.3777
Loa Loa (eye worm) hypothetical protein 0.002 0.0018 0.0018
Schistosoma mansoni hypothetical protein 0.005 0.0275 0.1045
Plasmodium falciparum plasmepsin VIII, putative 0.0028 0.009 0.0283
Loa Loa (eye worm) hypothetical protein 0.0063 0.0381 0.0381
Trypanosoma brucei lanosterol synthase 0.0148 0.1106 0.1997
Entamoeba histolytica short chain dehydrogenase family protein 0.002 0.0018 0.0018
Mycobacterium tuberculosis Probable ATP-dependent CLP protease proteolytic subunit 1 ClpP1 (endopeptidase CLP) 0.0051 0.028 0.0384
Plasmodium falciparum plasmepsin V 0.0028 0.009 0.0283
Brugia malayi PHD-finger family protein 0.0025 0.0062 0.0053
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.0063 0.0381 0.0372
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0019 0.0009 0.0001
Loa Loa (eye worm) hypothetical protein 0.0019 0.0009 0.0009
Schistosoma mansoni family M13 unassigned peptidase (M13 family) 0.0047 0.0247 0.0933
Echinococcus multilocularis geminin 0.0165 0.1253 0.184
Mycobacterium tuberculosis Inositol-1-monophosphatase SuhB 0.0032 0.0123 0.0154
Schistosoma mansoni short chain dehydrogenase 0.002 0.0018 0.0034
Echinococcus multilocularis thioredoxin glutathione reductase 0.0037 0.0165 0.0232
Brugia malayi ecdysteroid receptor 0.0063 0.0381 0.0373
Echinococcus multilocularis conserved hypothetical protein 0.002 0.0018 0.0013
Schistosoma mansoni zinc finger protein 0.002 0.0016 0.0029
Schistosoma mansoni acetylcholinesterase 0.0023 0.0048 0.0152
Onchocerca volvulus Protein ultraspiracle homolog 0.0063 0.0381 0.0372
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0036 0.0155 0.0304
Echinococcus multilocularis 3 ketodihydrosphingosine reductase 0.002 0.0018 0.0013
Brugia malayi nuclear hormone receptor 0.003 0.0101 0.0092
Echinococcus granulosus Nuclear hormone receptor HR96 0.003 0.0101 0.025
Brugia malayi Cation transporter family protein 0.0019 0.0009 0.0001
Schistosoma mansoni neprilysin-2 (M13 family) 0.0097 0.0673 0.26
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0035 0.0146 0.0539
Schistosoma mansoni acetyl-CoA C-acetyltransferase 0.0023 0.0041 0.0128
Brugia malayi Nuclear hormone receptor family member nhr-1 0.0063 0.0381 0.0373
Echinococcus granulosus geranylgeranyl transferase type I beta subunit 0.002 0.0022 0.0036
Schistosoma mansoni endothelin-converting enzyme-related 0.0047 0.0247 0.0933
Schistosoma mansoni Nep2 peptidase (M13 family) 0.0097 0.0673 0.26
Echinococcus multilocularis nAChR subunit 0.0019 0.0009 0.0001
Loa Loa (eye worm) hypothetical protein 0.0063 0.0381 0.0381
Trypanosoma cruzi metallo-peptidase, Clan MG, Family M24 0.0043 0.0219 0.0367
Onchocerca volvulus 0.0095 0.0658 0.0649
Schistosoma mansoni short-chain dehydrogenase/reductase 0.002 0.0018 0.0034
Toxoplasma gondii thioredoxin reductase 0.0037 0.0161 0.031
Echinococcus granulosus zinc finger protein 0.002 0.0016 0.002
Toxoplasma gondii oxidoreductase, short chain dehydrogenase/reductase family protein 0.002 0.0018 0.0018
Schistosoma mansoni integrin alpha-ps 0.0071 0.0455 0.1747
Schistosoma mansoni ecdysone-induced protein 78c (dr-78) 0.0033 0.0131 0.0477
Loa Loa (eye worm) nuclear receptor NHR-67 0.003 0.0101 0.0101
Schistosoma mansoni family M13 unassigned peptidase (M13 family) 0.0192 0.1481 0.5764
Loa Loa (eye worm) hypothetical protein 0.0023 0.0048 0.0048
Plasmodium falciparum plasmepsin IV 0.012 0.0864 0.3325
Onchocerca volvulus 0.002 0.0018 0.0008
Plasmodium vivax farnesyltransferase beta subunit, putative 0.002 0.0022 0.0017
Leishmania major myo-inositol-1(or 4)-monophosphatase 1, putative 0.0036 0.0155 0.0251
Brugia malayi Platelet-activating factor acetylhydrolase, plasma/intracellular isoform II family protein 0.0667 0.5503 0.5499
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0063 0.0381 0.0373
Loa Loa (eye worm) hypothetical protein 0.0192 0.1481 0.1481
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0062 0.0378 0.0671
Loa Loa (eye worm) hypothetical protein 0.0035 0.0146 0.0146
Brugia malayi TAR-binding protein 0.0062 0.0374 0.0365
Brugia malayi hypothetical protein 0.0033 0.0131 0.0122
Trichomonas vaginalis Clan MG, familly M24, aminopeptidase P-like metallopeptidase 0.0043 0.0219 0.0433
Trypanosoma cruzi 3-oxo-5-alpha-steroid 4-dehydrogenase, putative 0.032 0.2562 0.4639
Schistosoma mansoni short chain dehydrogenase 0.002 0.0018 0.0034
Plasmodium falciparum ataxin-2 like protein, putative 0.0025 0.0062 0.0173
Loa Loa (eye worm) hypothetical protein 0.0063 0.0381 0.0381
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0035 0.0146 0.0539
Loa Loa (eye worm) hypothetical protein 0.0019 0.0009 0.0009
Schistosoma mansoni carbonyl reductase 0.002 0.0018 0.0034
Echinococcus granulosus carbonyl reductase 1 0.002 0.0018 0.0024
Loa Loa (eye worm) hypothetical protein 0.0145 0.1083 0.1083
Mycobacterium ulcerans aldehyde dehydrogenase 0.0061 0.0366 0.0508
Loa Loa (eye worm) hypothetical protein 0.0066 0.0407 0.0407
Brugia malayi hypothetical protein 0.0033 0.0131 0.0122
Schistosoma mansoni family M13 unassigned peptidase (M13 family) 0.0097 0.0673 0.26
Echinococcus multilocularis carbonyl reductase 1 0.002 0.0018 0.0013
Echinococcus multilocularis ATP dependent Clp protease proteolytic subunit 0.0077 0.0507 0.0736
Trichomonas vaginalis 3-oxo-5-alpha-steroid 4-dehydrogenase, putative 0.06 0.4937 1
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0028 0.009 0.0316
Schistosoma mansoni RAR-like nuclear receptor 0.0063 0.0381 0.1459
Echinococcus granulosus epidermal retinal dehydrogenase 2 0.002 0.0018 0.0024
Echinococcus granulosus ecdysone induced protein 78C 0.0063 0.0381 0.1013
Plasmodium falciparum plasmepsin I 0.012 0.0864 0.3325
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.002 0.0018 0.0009
Trypanosoma cruzi phospholipase A2-like protein, putative 0.0306 0.2442 0.442
Trypanosoma cruzi PAB1-binding protein , putative 0.0025 0.0062 0.008
Echinococcus multilocularis tumor protein p63 0.033 0.2645 0.3899
Leishmania major sterol 24-c-methyltransferase, putative 0.0203 0.1573 0.2836
Loa Loa (eye worm) dehydrogenase 0.002 0.0018 0.0018
Loa Loa (eye worm) hypothetical protein 0.003 0.0101 0.0101
Echinococcus multilocularis telomerase reverse transcriptase subunit 0.0086 0.0583 0.0849
Brugia malayi Peptidase family M13 containing protein 0.0192 0.1481 0.1473
Schistosoma mansoni nuclear receptor nhr-48 0.003 0.0101 0.036
Plasmodium vivax aspartyl proteinase, putative 0.012 0.0864 0.3325
Loa Loa (eye worm) hypothetical protein 0.0142 0.1055 0.1055
Toxoplasma gondii inositol(myo)-1(or 4)-monophosphatase 2, putative 0.0036 0.0155 0.0298
Entamoeba histolytica methionine aminopeptidase, putative 0.0043 0.0219 0.0426
Brugia malayi initiation factor 2-associated protein. 0.0043 0.0219 0.021
Onchocerca volvulus Bile acid receptor homolog 0.0063 0.0381 0.0372
Entamoeba histolytica estradiol 17-beta-dehydrogenase, putative 0.002 0.0018 0.0018
Trypanosoma cruzi 3-oxo-5-alpha-steroid 4-dehydrogenase, putative 0.06 0.4937 0.8967
Schistosoma mansoni hypothetical protein 0.005 0.0275 0.1045
Plasmodium vivax aspartyl proteinase, putative 0.0028 0.009 0.0283
Echinococcus multilocularis nicotinic acetylcholine receptor beta 1 subunit 0.0019 0.0009 0.0001
Giardia lamblia Prenyltransferase 0.002 0.0022 0.0017
Echinococcus multilocularis fetal alzheimer antigen, falz 0.0023 0.0041 0.0048
Mycobacterium leprae possible inositol monophosphatase SubH (IMPase) (inositol-1-phosphatase) (I-1-Pase ). 0.0032 0.0123 0.0723
Trichomonas vaginalis type I geranylgeranyltransferase beta subunit, putative 0.002 0.0022 0.0033
Schistosoma mansoni ephrin receptor 0.0065 0.0397 0.1521
Echinococcus multilocularis glycine receptor subunit beta 0.0019 0.0009 0.0001
Schistosoma mansoni steroid dehydrogenase 0.002 0.0018 0.0034
Loa Loa (eye worm) nicotinic acetylcholine receptor non-alpha subunit 0.0019 0.0009 0.0009
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.0063 0.0381 0.0381
Trichomonas vaginalis AGC family protein kinase 0.0019 0.0009 0.0007
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.0063 0.0381 0.0551
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.0063 0.0381 0.0381
Trichomonas vaginalis spcc417.12 protein, putative 0.0023 0.0048 0.0086
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0035 0.0146 0.0138
Echinococcus granulosus peptidase Clp S14 family 0.0051 0.028 0.0738
Trypanosoma cruzi sterol 24-c-methyltransferase, putative 0.0203 0.1573 0.2836
Echinococcus granulosus retinol dehydrogenase 11 0.002 0.0018 0.0024
Loa Loa (eye worm) oxidoreductase 0.002 0.0018 0.0018
Mycobacterium tuberculosis NAD(P)H quinone reductase LpdA 0.0093 0.064 0.0908
Trichomonas vaginalis AGC family protein kinase 0.0019 0.0009 0.0007
Trypanosoma cruzi phospholipase A1, putative 0.0667 0.5503 1
Loa Loa (eye worm) thioredoxin reductase 0.0037 0.0161 0.0161
Brugia malayi nuclear receptor RXR 0.003 0.0101 0.0092
Leishmania major phospholipase A1, putative 0.0667 0.5503 1
Toxoplasma gondii aspartyl protease ASP1 0.012 0.0864 0.1735
Brugia malayi ephrin receptor 1 precursor 0.0031 0.0111 0.0102
Echinococcus granulosus Protein kinase C brain isozyme 0.0121 0.0877 0.236
Onchocerca volvulus 0.0023 0.0048 0.0038
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0019 0.0009 0.0001
Trypanosoma cruzi hypothetical protein, conserved 0.002 0.0022 0.0008
Onchocerca volvulus 0.0035 0.0146 0.0137
Mycobacterium ulcerans zinc metalloprotease 0.0192 0.1481 0.2135
Loa Loa (eye worm) peptidase family M13 containing protein 0.0142 0.1055 0.1055
Loa Loa (eye worm) short chain dehydrogenase/reductase family oxidoreductase 0.002 0.0018 0.0018
Loa Loa (eye worm) RNA recognition domain-containing protein domain-containing protein 0.0062 0.0374 0.0374
Loa Loa (eye worm) hypothetical protein 0.0192 0.1481 0.1481
Toxoplasma gondii oxidoreductase, short chain dehydrogenase/reductase family protein 0.002 0.0018 0.0018
Schistosoma mansoni gliotactin 0.0023 0.0048 0.0152
Trichomonas vaginalis AGC family protein kinase 0.0019 0.0009 0.0007
Trichomonas vaginalis AGC family protein kinase 0.0019 0.0009 0.0007
Brugia malayi Hypothetical glycine receptor like protein T20B12.9 in chromosome III 0.0019 0.0009 0.0001
Loa Loa (eye worm) hypothetical protein 0.003 0.0101 0.0101
Mycobacterium ulcerans beta-lactamase 0.0035 0.0146 0.0188
Echinococcus multilocularis nicotinic acetylcholine receptor subunit alpha 8 0.0019 0.0009 0.0001
Toxoplasma gondii LsmAD domain-containing protein 0.0025 0.0062 0.0107
Loa Loa (eye worm) hypothetical protein 0.0019 0.0009 0.0009
Echinococcus multilocularis acetylcholine receptor subunit beta 1 0.0019 0.0009 0.0001
Mycobacterium ulcerans aldehyde dehydrogenase 0.0061 0.0366 0.0508
Loa Loa (eye worm) hypothetical protein 0.002 0.0018 0.0018
Schistosoma mansoni serine/threonine protein kinase 0.0121 0.0877 0.3401
Loa Loa (eye worm) oxidoreductase 0.002 0.0018 0.0018
Onchocerca volvulus 0.0667 0.5503 0.5499
Loa Loa (eye worm) hypothetical protein 0.01 0.0695 0.0695
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0063 0.0381 0.0373
Echinococcus multilocularis protein kinase c iota type 0.0032 0.0121 0.0166
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.0047 0.0245 0.0237
Loa Loa (eye worm) hypothetical protein 0.0063 0.0381 0.0381
Schistosoma mansoni steroid dehydrogenase 0.002 0.0018 0.0034
Mycobacterium tuberculosis Probable esterase LipL 0.0035 0.0146 0.0188
Schistosoma mansoni short chain dehydrogenase 0.002 0.0018 0.0034
Loa Loa (eye worm) zinc metallopeptidase 4 0.0047 0.0247 0.0247
Echinococcus granulosus glycine receptor subunit alpha 1 0.0019 0.0009 0.0002
Echinococcus multilocularis Nuclear hormone receptor HR96 0.003 0.0101 0.0136
Brugia malayi RNA binding protein 0.0062 0.0374 0.0365
Echinococcus granulosus retinoic acid receptor rxr beta a 0.0063 0.0381 0.1013
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0019 0.0009 0.0001
Plasmodium falciparum 3-oxo-5-alpha-steroid 4-dehydrogenase, putative 0.032 0.2562 1
Echinococcus granulosus steroid dehydrogenase 0.002 0.0018 0.0024
Echinococcus granulosus thyroid hormone receptor alpha 0.003 0.0101 0.025
Trypanosoma cruzi phospholipase A2-like protein, putative 0.0306 0.2442 0.442
Trypanosoma cruzi geranylgeranyl transferase type II beta subunit, putative 0.002 0.0022 0.0008
Loa Loa (eye worm) TK/EPH protein kinase 0.0082 0.0546 0.0546
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.003 0.0101 0.0091
Schistosoma mansoni hepatocyte nuclear factor 4-alpha (hnf-4-alpha) 0.003 0.0101 0.036
Schistosoma mansoni hypothetical protein 0.005 0.0275 0.1045
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0019 0.0009 0.0001
Toxoplasma gondii prenyltransferase and squalene oxidase repeat-containing protein 0.002 0.0022 0.0027
Brugia malayi Integrin alpha pat-2 precursor 0.0306 0.2442 0.2435
Brugia malayi acetylcholine receptor protein, alpha-like chain, putative 0.0019 0.0009 0.0001
Echinococcus granulosus hypothetical protein 0.002 0.0018 0.0024
Schistosoma mansoni zinc finger protein 0.003 0.0101 0.036
Trypanosoma brucei PAB1-binding protein , putative 0.0025 0.0062 0.0096
Loa Loa (eye worm) hypothetical protein 0.003 0.0101 0.0101
Echinococcus granulosus neuronal acetylcholine receptor subunit alpha 4 0.0019 0.0009 0.0002
Leishmania major cathepsin L-like protease 0.0062 0.0378 0.0656
Schistosoma mansoni nuclear hormone receptor 0.003 0.0101 0.036
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.0063 0.0381 0.1459
Brugia malayi 3-hydroxyacyl-CoA dehydrogenase type II 0.002 0.0018 0.0009
Mycobacterium tuberculosis Carboxylesterase LipT 0.0023 0.0048 0.0044
Echinococcus multilocularis glycine receptor subunit alpha 1 0.0019 0.0009 0.0001
Onchocerca volvulus Sepiapterin reductase homolog 0.002 0.0018 0.0008
Loa Loa (eye worm) hypothetical protein 0.012 0.0864 0.0864
Loa Loa (eye worm) hypothetical protein 0.002 0.0018 0.0018
Loa Loa (eye worm) hypothetical protein 0.003 0.0101 0.0101
Brugia malayi Carboxylesterase family protein 0.0138 0.1021 0.1013
Mycobacterium tuberculosis Possible penicillin-binding protein 0.0223 0.1744 0.2519
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.002 0.0018 0.0009
Loa Loa (eye worm) hypothetical protein 0.0145 0.1083 0.1083
Loa Loa (eye worm) DR-78 0.003 0.0101 0.0101
Brugia malayi Hypothetical oxidoreductase F56D1.5 0.002 0.0018 0.0009
Loa Loa (eye worm) oxidoreductase 0.002 0.0018 0.0018
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.002 0.0018 0.0009
Plasmodium falciparum plasmepsin IX 0.0028 0.009 0.0283
Brugia malayi nicotinic acetylcholine receptor beta-1 chain precursor 0.0019 0.0009 0.0001
Entamoeba histolytica geranylgeranyl transferase beta subunit 0.002 0.0022 0.0027
Echinococcus multilocularis transient receptor potential cation channel 0.002 0.0018 0.0013
Brugia malayi Nuclear hormone receptor-like 1 0.0033 0.0131 0.0122
Trichomonas vaginalis conserved hypothetical protein 0.032 0.2562 0.5185
Echinococcus multilocularis nicotinic acetylcholine receptor alpha subunit 0.0019 0.0009 0.0001
Brugia malayi orphan nuclear receptor NR2E1 0.003 0.0101 0.0092
Mycobacterium ulcerans ATP-dependent Clp protease proteolytic subunit 0.0077 0.0507 0.0714
Mycobacterium leprae DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE 0.0093 0.064 0.4251
Mycobacterium tuberculosis NADPH-dependent mycothiol reductase Mtr 0.0037 0.0161 0.021
Plasmodium vivax plasmepsin V, putative 0.0028 0.009 0.0283
Echinococcus granulosus FTZ F1 alpha 0.0063 0.0381 0.1013
Brugia malayi ecdysone receptor 0.003 0.0101 0.0092
Plasmodium vivax geranylgeranyltransferase, putative 0.002 0.0022 0.0017
Schistosoma mansoni hypothetical protein 0.005 0.0275 0.1045
Trichomonas vaginalis AGC family protein kinase 0.0019 0.0009 0.0007
Trypanosoma brucei sterol 24-c-methyltransferase, putative 0.0203 0.1573 0.2847
Loa Loa (eye worm) hypothetical protein 0.0033 0.0131 0.0131
Brugia malayi Prenyltransferase and squalene oxidase repeat family protein 0.002 0.0022 0.0013
Trypanosoma cruzi lanosterol synthase, putative 0.0148 0.1106 0.1985
Loa Loa (eye worm) hypothetical protein 0.003 0.0101 0.0101
Trichomonas vaginalis inositol monophosphatase, putative 0.0036 0.0155 0.0304
Echinococcus granulosus glycine receptor subunit alpha 1 0.0019 0.0009 0.0002
Trichomonas vaginalis D-aminoacylase, putative 0.0035 0.0146 0.0286
Schistosoma mansoni hypothetical protein 0.0047 0.0245 0.0925
Schistosoma mansoni nAChR subunit 0.0019 0.0009 0.0003
Loa Loa (eye worm) hypothetical protein 0.002 0.0018 0.0018
Plasmodium vivax aspartyl protease, putative 0.0028 0.009 0.0283
Echinococcus multilocularis neuronal acetylcholine receptor subunit alpha 4 0.0019 0.0009 0.0001
Echinococcus multilocularis Rab geranylgeranyltransferase, beta subunit 0.002 0.0022 0.0019
Schistosoma mansoni tar DNA-binding protein 0.0062 0.0374 0.143
Plasmodium vivax methionine aminopeptidase 2, putative 0.0043 0.0219 0.0791
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0036 0.0155 0.0251
Loa Loa (eye worm) hypothetical protein 0.002 0.0022 0.0022
Leishmania major cathepsin L-like protease 0.0062 0.0378 0.0656
Loa Loa (eye worm) beta-lactamase 0.0035 0.0146 0.0146
Plasmodium vivax ataxin-2 like protein, putative 0.0025 0.0062 0.0173
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.002 0.0018 0.0009
Onchocerca volvulus 0.0023 0.0048 0.0038
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.0035 0.0146 0.0188
Plasmodium falciparum plasmepsin VI 0.012 0.0864 0.3325
Schistosoma mansoni nAChR subunit 0.0019 0.0009 0.0003
Echinococcus granulosus hypothetical protein 0.002 0.0018 0.0024
Toxoplasma gondii oxidoreductase, putative 0.002 0.0018 0.0018
Echinococcus multilocularis BC026374 protein (S09 family) 0.0023 0.0048 0.0058
Loa Loa (eye worm) RNA binding protein 0.0062 0.0374 0.0374
Schistosoma mansoni steroid dehydrogenase 0.002 0.0018 0.0034
Leishmania major trypanothione reductase 0.0037 0.0161 0.0262
Brugia malayi Neurotransmitter-gated ion-channel transmembrane region family protein 0.0019 0.0009 0.0001
Brugia malayi Carboxylesterase family protein 0.0023 0.0048 0.0039
Schistosoma mansoni neuroligin 3 (S09 family) 0.0023 0.0048 0.0152
Loa Loa (eye worm) carboxylesterase 0.0023 0.0048 0.0048
Schistosoma mansoni retinal dehydrogenase 0.002 0.0018 0.0034
Loa Loa (eye worm) hypothetical protein 0.0019 0.0009 0.0009
Onchocerca volvulus 0.002 0.0018 0.0008
Schistosoma mansoni family S9 non-peptidase homologue (S09 family) 0.0023 0.0048 0.0152
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0062 0.0378 0.0671
Loa Loa (eye worm) hypothetical protein 0.0145 0.1083 0.1083
Loa Loa (eye worm) hypothetical protein 0.0023 0.0048 0.0048
Schistosoma mansoni nuclear receptor 0.003 0.0101 0.036
Brugia malayi D-beta-hydroxybutyrate dehydrogenase, mitochondrial precursor 0.002 0.0018 0.0009
Echinococcus multilocularis RNA directed DNA polymerase 0.0086 0.0583 0.0849
Schistosoma mansoni steroid dehydrogenase 0.002 0.0018 0.0034
Echinococcus multilocularis steroid dehydrogenase 0.002 0.0018 0.0013
Toxoplasma gondii oxidoreductase, short chain dehydrogenase/reductase family protein 0.002 0.0018 0.0018
Trichomonas vaginalis conserved hypothetical protein 0.032 0.2562 0.5185
Schistosoma mansoni nuclear hormone receptor 0.0063 0.0381 0.1459
Echinococcus multilocularis epidermal retinal dehydrogenase 2 0.002 0.0018 0.0013
Schistosoma mansoni short chain dehydrogenase 0.002 0.0018 0.0034
Schistosoma mansoni steroid dehydrogenase 0.002 0.0018 0.0034
Schistosoma mansoni aldehyde dehydrogenase 0.0061 0.0366 0.1399
Schistosoma mansoni thyroid hormone receptor 0.0063 0.0381 0.1459
Loa Loa (eye worm) acetylcholinesterase 1 0.0138 0.1021 0.1021
Schistosoma mansoni tar DNA-binding protein 0.0062 0.0374 0.143
Echinococcus multilocularis acetylcholinesterase 0.0138 0.1021 0.1496
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0179 0.1364 0.3682
Loa Loa (eye worm) integrin alpha pat-2 0.0471 0.3845 0.3845
Loa Loa (eye worm) hypothetical protein 0.002 0.0018 0.0018
Schistosoma mansoni inositol monophosphatase 0.0036 0.0155 0.0574
Schistosoma mansoni short chain dehydrogenase 0.002 0.0018 0.0034
Loa Loa (eye worm) glutathione reductase 0.0037 0.0161 0.0161
Loa Loa (eye worm) hypothetical protein 0.003 0.0101 0.0101
Loa Loa (eye worm) AGC/AKT protein kinase 0.0019 0.0009 0.0009
Echinococcus multilocularis para nitrobenzyl esterase 0.0023 0.0048 0.0058
Echinococcus multilocularis carbonyl reductase 1 0.002 0.0018 0.0013
Toxoplasma gondii aldehyde dehydrogenase 0.0061 0.0366 0.0725
Onchocerca volvulus 0.0035 0.0146 0.0137
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.0063 0.0381 0.0381
Brugia malayi hypothetical protein 0.003 0.0101 0.0092
Schistosoma mansoni Cys-loop ligand gated ion channel subunit 0.0019 0.0009 0.0003
Brugia malayi Cation transporter family protein 0.0019 0.0009 0.0001
Loa Loa (eye worm) hypothetical protein 0.0035 0.0146 0.0146
Loa Loa (eye worm) hypothetical protein 0.002 0.0018 0.0018
Schistosoma mansoni endothelin-converting enzyme-like 1 (damage-induced neuronal endopeptidase) 0.0047 0.0247 0.0933
Trypanosoma brucei phospholipase A1, putative 0.0667 0.5503 1
Loa Loa (eye worm) hypothetical protein 0.002 0.0018 0.0018
Trichomonas vaginalis geranylgeranyl transferase type I beta subunit, putative 0.002 0.0022 0.0033
Wolbachia endosymbiont of Brugia malayi fructose-1,6-bisphosphatase 0.0036 0.0155 0.2819
Plasmodium vivax polyprenol reductase, putative 0.032 0.2562 1
Trichomonas vaginalis Clan MG, familly M24, aminopeptidase P-like metallopeptidase 0.0043 0.0219 0.0433
Toxoplasma gondii oxidoreductase, putative 0.002 0.0018 0.0018
Plasmodium falciparum ATP-dependent Clp protease proteolytic subunit 0.0077 0.0507 0.1922
Loa Loa (eye worm) hypothetical protein 0.0038 0.0176 0.0176
Toxoplasma gondii ABC1 family protein 0.0035 0.0146 0.0279
Loa Loa (eye worm) hypothetical protein 0.003 0.0101 0.0101
Loa Loa (eye worm) nuclear receptor nhr-7B 0.003 0.0101 0.0101
Brugia malayi hypothetical protein 0.0046 0.0242 0.0233
Trichomonas vaginalis protein farnesyltransferase beta subunit, putative 0.002 0.0022 0.0033
Loa Loa (eye worm) initiation factor 2-associated protein 0.0043 0.0219 0.0219
Loa Loa (eye worm) hypothetical protein 0.0142 0.1055 0.1055
Trichomonas vaginalis AGC family protein kinase 0.0019 0.0009 0.0007
Mycobacterium leprae conserved hypothetical protein 0.0035 0.0146 0.088
Loa Loa (eye worm) hypothetical protein 0.0023 0.0048 0.0048
Brugia malayi Kelch motif family protein 0.0046 0.0242 0.0233
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.0063 0.0381 0.0381
Trypanosoma cruzi 3-oxo-5-alpha-steroid 4-dehydrogenase, putative 0.06 0.4937 0.8967
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0063 0.0381 0.0551
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0062 0.0378 0.0671
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0028 0.009 0.0316
Echinococcus multilocularis integrin alpha ps 0.0066 0.0407 0.0589
Trichomonas vaginalis AGC family protein kinase 0.0019 0.0009 0.0007
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.002 0.0018 0.0009
Loa Loa (eye worm) hypothetical protein 0.0019 0.0009 0.0009
Echinococcus granulosus Nuclear hormone receptor HR96 0.003 0.0101 0.025
Onchocerca volvulus 0.003 0.0101 0.0091
Trichomonas vaginalis AGC family protein kinase 0.0019 0.0009 0.0007
Loa Loa (eye worm) hypothetical protein 0.0023 0.0048 0.0048
Mycobacterium tuberculosis Probable dehydrogenase 0.0084 0.056 0.0792
Loa Loa (eye worm) hypothetical protein 0.0035 0.0146 0.0146
Echinococcus multilocularis inositol monophosphatase 1 0.0036 0.0155 0.0217
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0179 0.1364 0.1356
Schistosoma mansoni geranylgeranyl transferase type I beta subunit 0.002 0.0022 0.0051
Schistosoma mansoni tar DNA-binding protein 0.0062 0.0374 0.143
Schistosoma mansoni family M13 unassigned peptidase (M13 family) 0.005 0.0275 0.1045
Schistosoma mansoni aldehyde dehydrogenase 0.0061 0.0366 0.1399
Trypanosoma cruzi sterol 24-c-methyltransferase, putative 0.0203 0.1573 0.2836
Echinococcus granulosus para nitrobenzyl esterase 0.0023 0.0048 0.0106
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0179 0.1364 0.3682
Plasmodium vivax aspartyl protease, putative 0.0028 0.009 0.0283
Plasmodium falciparum geranylgeranyltransferase, putative 0.002 0.0022 0.0017
Loa Loa (eye worm) hypothetical protein 0.0019 0.0009 0.0009
Loa Loa (eye worm) oxidoreductase 0.002 0.0018 0.0018
Trypanosoma cruzi hypothetical protein, conserved 0.002 0.0022 0.0008
Echinococcus multilocularis oxidoreductase 0.002 0.0018 0.0013
Plasmodium falciparum plasmepsin X 0.0028 0.009 0.0283
Onchocerca volvulus Methionine aminopeptidase 2 homolog 0.0043 0.0219 0.0209
Toxoplasma gondii prenyltransferase and squalene oxidase repeat-containing protein 0.002 0.0022 0.0027
Brugia malayi acetylcholine receptor, alpha-type subunit unc-38 precursor 0.0019 0.0009 0.0001
Echinococcus multilocularis Dehydrogenase:reductase SDR family 0.002 0.0018 0.0013
Loa Loa (eye worm) AGC/RSK/RSK protein kinase 0.0019 0.0009 0.0009
Echinococcus multilocularis steroid dehydrogenase 0.002 0.0018 0.0013
Brugia malayi Bromodomain containing protein 0.0075 0.0487 0.0479
Brugia malayi Dehydrogenases, short chain protein 30 0.002 0.0018 0.0009
Brugia malayi Integrin beta pat-3 precursor 0.0304 0.2429 0.2422
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0179 0.1364 0.5306
Brugia malayi Nuclear hormone receptor E75 0.003 0.0101 0.0092
Onchocerca volvulus 0.0048 0.0259 0.025
Mycobacterium tuberculosis Putative ferredoxin reductase 0.0084 0.056 0.0792
Trichomonas vaginalis 3-oxo-5-alpha-steroid 4-dehydrogenase, putative 0.06 0.4937 1
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.006 0.0357 0.0515
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.002 0.0018 0.0009
Loa Loa (eye worm) hypothetical protein 0.0138 0.1021 0.1021
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.0063 0.0381 0.0551
Trypanosoma brucei short-chain dehydrogenase, putative 0.002 0.0018 0.0016
Schistosoma mansoni nAChR subunit 0.0019 0.0009 0.0003
Brugia malayi hypothetical protein 0.0228 0.1787 0.178
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0063 0.0381 0.1013
Onchocerca volvulus 0.002 0.0018 0.0008
Onchocerca volvulus 0.0023 0.0048 0.0038
Echinococcus granulosus synaptic glycoprotein sc2 0.032 0.2562 0.694
Trypanosoma brucei short-chain dehydrogenase, putative 0.002 0.0018 0.0016
Brugia malayi Probable protein farnesyltransferase beta subunit, putative 0.002 0.0022 0.0013
Echinococcus granulosus oxidoreductase 0.002 0.0018 0.0024
Mycobacterium tuberculosis Probable ATP-dependent CLP protease proteolytic subunit 2 ClpP2 (endopeptidase CLP 2) 0.0051 0.028 0.0384
Echinococcus multilocularis synaptic glycoprotein sc2 0.032 0.2562 0.3777
Brugia malayi follicle stimulating hormone receptor 0.0234 0.1838 0.1831
Echinococcus multilocularis integrin alpha ps 0.0137 0.1012 0.1483
Schistosoma mansoni steroid dehydrogenase 0.002 0.0018 0.0034
Trypanosoma brucei trypanothione reductase 0.0037 0.0161 0.0278
Trichomonas vaginalis D-aminoacylase, putative 0.0035 0.0146 0.0286
Trichomonas vaginalis D-aminoacylase, putative 0.0035 0.0146 0.0286
Echinococcus granulosus nicotinic acetylcholine receptor a11 subunit 0.0019 0.0009 0.0002
Schistosoma mansoni nAChR subunit 0.0019 0.0009 0.0003
Loa Loa (eye worm) hypothetical protein 0.0019 0.0009 0.0009
Schistosoma mansoni nAChR subunit (ShAR1-beta2-like) 0.0019 0.0009 0.0003
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0179 0.1364 0.2004
Loa Loa (eye worm) hypothetical protein 0.0025 0.0062 0.0062
Brugia malayi protein kinase C II. 0.0035 0.0144 0.0136
Schistosoma mansoni nAChR subunit 0.0019 0.0009 0.0003
Mycobacterium ulcerans hypothetical protein 0.0035 0.0146 0.0188
Brugia malayi Protein kinase c protein 2 0.0103 0.0722 0.0714
Schistosoma mansoni survival motor neuron protein 0.0047 0.0245 0.0925
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0033 0.0131 0.0477
Toxoplasma gondii oxidoreductase, short chain dehydrogenase/reductase family protein 0.002 0.0018 0.0018
Loa Loa (eye worm) oxidoreductase 0.002 0.0018 0.0018
Mycobacterium tuberculosis Probable conserved lipoprotein 0.0035 0.0146 0.0188
Echinococcus granulosus nicotinic acetylcholine receptor subunit alpha 8 0.0019 0.0009 0.0002
Echinococcus multilocularis retinol dehydrogenase 11 0.002 0.0018 0.0013
Echinococcus multilocularis thyroid hormone receptor alpha 0.0063 0.0381 0.0551
Loa Loa (eye worm) hypothetical protein 0.0019 0.0009 0.0009
Brugia malayi Nuclear hormone receptor family member nhr-41 0.0063 0.0381 0.0373
Echinococcus multilocularis family S9 non peptidase ue (S09 family) 0.0023 0.0048 0.0058
Echinococcus multilocularis carbonyl reductase 1 0.002 0.0018 0.0013
Schistosoma mansoni cathepsin D (A01 family) 0.0212 0.1647 0.6416
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0028 0.009 0.0316
Trichomonas vaginalis Clan MG, familly M24, aminopeptidase P-like metallopeptidase 0.0043 0.0219 0.0433
Loa Loa (eye worm) prenyltransferase and squalene oxidase repeat family protein 0.002 0.0022 0.0022
Brugia malayi Nuclear hormone receptor E75 0.003 0.0101 0.0092
Loa Loa (eye worm) hypothetical protein 0.0063 0.0381 0.0381
Giardia lamblia Methionine aminopeptidase 0.0043 0.0219 0.0791
Loa Loa (eye worm) hypothetical protein 0.0019 0.0009 0.0009
Onchocerca volvulus Dehydrogenase\/reductase SDR family member 13 homolog 0.002 0.0018 0.0008
Toxoplasma gondii methionine aminopeptidase 2, putative 0.0043 0.0219 0.0426
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0028 0.009 0.0316
Echinococcus multilocularis nicotinic acetylcholine receptor a11 subunit 0.0019 0.0009 0.0001
Loa Loa (eye worm) hypothetical protein 0.0192 0.1481 0.1481
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0062 0.0378 0.0671
Brugia malayi peptidase family M13 containing protein 0.0047 0.0247 0.0239
Loa Loa (eye worm) hypothetical protein 0.0033 0.0131 0.0131
Loa Loa (eye worm) hypothetical protein 0.0063 0.0381 0.0381
Echinococcus multilocularis Cys loop ligand gated ion channel subunit 0.0019 0.0009 0.0001
Mycobacterium ulcerans ATP-dependent Clp protease proteolytic subunit 0.0077 0.0507 0.0714
Schistosoma mansoni carbonyl reductase 0.002 0.0018 0.0034
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.002 0.0018 0.0009
Entamoeba histolytica hypothetical protein, conserved 0.002 0.0018 0.0018
Schistosoma mansoni family M13 non-peptidase homologue (M13 family) 0.0047 0.0247 0.0933
Echinococcus multilocularis geranylgeranyl transferase type I beta subunit 0.002 0.0022 0.0019
Echinococcus multilocularis carbonyl reductase 1 0.002 0.0018 0.0013
Schistosoma mansoni family M13 non-peptidase homologue (M13 family) 0.0097 0.0673 0.26
Brugia malayi nuclear receptor NHR-88 0.0063 0.0381 0.0373
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0019 0.0009 0.0001
Echinococcus multilocularis glycine receptor subunit alpha 1 0.0019 0.0009 0.0001
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.002 0.0018 0.0009
Echinococcus granulosus cathepsin d lysosomal aspartyl protease 0.012 0.0864 0.2323
Mycobacterium ulcerans carboxylesterase, LipT 0.0023 0.0048 0.0044
Brugia malayi Nuclear hormone receptor-like 1 0.0063 0.0381 0.0373
Loa Loa (eye worm) peptidase family M13 containing protein 0.0142 0.1055 0.1055
Echinococcus granulosus nuclear receptor subfamily 4 group A 0.003 0.0101 0.025
Brugia malayi acetylcholine receptor alpha subunit precursor, putative 0.0019 0.0009 0.0001
Loa Loa (eye worm) hypothetical protein 0.0019 0.0009 0.0009
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.0063 0.0381 0.1013
Onchocerca volvulus Phospholipase A2 homolog 0.0368 0.2973 0.2966
Schistosoma mansoni synaptic glycoprotein sc2 related 0.032 0.2562 1
Loa Loa (eye worm) hypothetical protein 0.1197 1 1
Schistosoma mansoni steroid hormone receptor ad4bp 0.0063 0.0381 0.1459
Schistosoma mansoni serine/threonine protein kinase 0.0121 0.0877 0.3401
Loa Loa (eye worm) oxidoreductase 0.002 0.0018 0.0018
Loa Loa (eye worm) nicotinic acetylcholine receptor alpha subunit 0.0019 0.0009 0.0009
Loa Loa (eye worm) oxidoreductase 0.002 0.0018 0.0018
Brugia malayi Carboxylesterase family protein 0.0023 0.0048 0.0039
Echinococcus granulosus WW domain containing oxidoreductase 0.002 0.0018 0.0024
Trichomonas vaginalis geranylgeranyl transferase type II beta subunit, putative 0.002 0.0022 0.0033
Loa Loa (eye worm) hypothetical protein 0.0019 0.0009 0.0009
Echinococcus multilocularis cathepsin d (lysosomal aspartyl protease) 0.012 0.0864 0.1264
Trypanosoma cruzi metallo-peptidase, Clan MG, Family M24 0.0043 0.0219 0.0367
Loa Loa (eye worm) hypothetical protein 0.003 0.0101 0.0101
Onchocerca volvulus 0.0023 0.0048 0.0038
Brugia malayi steroid hormone receptor 0.0063 0.0381 0.0373
Trypanosoma cruzi cysteine peptidase, putative 0.0062 0.0378 0.0656
Schistosoma mansoni tar DNA-binding protein 0.0062 0.0374 0.143
Brugia malayi beta-lactamase family protein 0.0035 0.0146 0.0138
Mycobacterium tuberculosis Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras 0.0093 0.064 0.0908
Trypanosoma cruzi protein farnesyltransferase, putative 0.002 0.0022 0.0008
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0179 0.1364 0.2004
Schistosoma mansoni nuclear hormone receptor 0.003 0.0101 0.036
Leishmania major geranylgeranyltransferase, putative 0.002 0.0022 0.0008
Onchocerca volvulus 0.002 0.0018 0.0008
Trichomonas vaginalis short-chain dehydrogenases/reductase, putative 0.002 0.0018 0.0025
Echinococcus multilocularis ecdysone induced protein 78C 0.0063 0.0381 0.0551
Brugia malayi beta-lactamase 0.0035 0.0146 0.0138
Echinococcus multilocularis 3 hydroxyacyl coenzyme A dehydrogenase type 2 0.002 0.0018 0.0013
Echinococcus multilocularis protein kinase c epsilon type 0.0035 0.0144 0.0201
Mycobacterium tuberculosis Probable lipase LipE 0.0035 0.0146 0.0188
Mycobacterium tuberculosis Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB 0.0084 0.056 0.0792
Echinococcus granulosus endothelin converting enzyme 1 0.0192 0.1481 0.4
Loa Loa (eye worm) AGC/RSK/MSK protein kinase 0.0019 0.0009 0.0009
Brugia malayi Carboxylesterase family protein 0.0023 0.0048 0.0039
Brugia malayi Inositol-1 0.0036 0.0155 0.0147
Echinococcus multilocularis tar DNA binding protein 0.0062 0.0374 0.054
Schistosoma mansoni hypothetical protein 0.0021 0.0025 0.0064
Entamoeba histolytica estradiol 17-beta-dehydrogenase, putative 0.002 0.0018 0.0018
Loa Loa (eye worm) hypothetical protein 0.002 0.0018 0.0018
Mycobacterium ulcerans lipase LipD 0.0035 0.0146 0.0188
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0063 0.0381 0.0373
Echinococcus granulosus glycine receptor subunit beta 0.0019 0.0009 0.0002
Trypanosoma brucei sterol 24-c-methyltransferase, putative 0.0203 0.1573 0.2847
Echinococcus multilocularis estradiol 17 beta dehydrogenase 12 0.002 0.0018 0.0013
Brugia malayi nuclear hormone receptor 0.0063 0.0381 0.0373
Leishmania major hypothetical protein, conserved 0.0025 0.0062 0.008
Trypanosoma cruzi lanosterol synthase, putative 0.0148 0.1106 0.1985
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.0063 0.0381 0.0381
Trypanosoma cruzi cruzipain precursor, putative 0.0062 0.0378 0.0656
Echinococcus granulosus nicotinic acetylcholine receptor alpha subunit 0.0019 0.0009 0.0002
Brugia malayi Pepsin A precursor 0.0028 0.009 0.0081
Loa Loa (eye worm) hypothetical protein 0.0086 0.0583 0.0583
Trichomonas vaginalis penicillin-binding protein, putative 0.0035 0.0146 0.0286
Echinococcus granulosus glycine receptor subunit beta 0.0019 0.0009 0.0002
Trichomonas vaginalis geranylgeranyl transferase type I beta subunit, putative 0.002 0.0022 0.0033
Echinococcus multilocularis survival motor neuron protein 1 0.0228 0.1787 0.263
Trypanosoma brucei beta-D-hydroxybutyrate dehydrogenase 0.002 0.0018 0.0016
Echinococcus granulosus integrin alpha 3 0.0234 0.1837 0.4968
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0063 0.0381 0.0551
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.002 0.0018 0.0009
Toxoplasma gondii peptidase family M13 protein 0.0192 0.1481 0.2987
Trichomonas vaginalis geranylgeranyl transferase type II beta subunit, putative 0.002 0.0022 0.0033
Entamoeba histolytica 3-ketodihydrosphingosine reductase protein, putative 0.002 0.0018 0.0018
Schistosoma mansoni bromodomain containing protein 0.0063 0.0388 0.1484
Mycobacterium tuberculosis Probable oxidoreductase 0.0828 0.687 1
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.002 0.0018 0.0009
Loa Loa (eye worm) hypothetical protein 0.0023 0.0048 0.0048
Loa Loa (eye worm) excitatory GABA receptor EXP-1A 0.0019 0.0009 0.0009
Brugia malayi 3-oxo-5-alpha-steroid 4-dehydrogenase 1 0.06 0.4937 0.4932
Echinococcus multilocularis endothelin converting enzyme 1 0.0192 0.1481 0.2177
Trypanosoma cruzi hypothetical protein, conserved 0.0035 0.0146 0.0235
Brugia malayi dehydrogenases, short chain protein 9 0.002 0.0018 0.0009
Trichomonas vaginalis short-chain dehydrogenase, putative 0.002 0.0018 0.0025
Loa Loa (eye worm) hypothetical protein 0.0043 0.0212 0.0212
Brugia malayi tailless protein 0.003 0.0101 0.0092
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0063 0.0381 0.0373
Echinococcus multilocularis glycine receptor subunit beta 0.0019 0.0009 0.0001
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0063 0.0381 0.0373
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.0035 0.0146 0.0188
Onchocerca volvulus 0.002 0.0018 0.0008
Schistosoma mansoni hypothetical protein 0.0165 0.1253 0.4872
Entamoeba histolytica myo-inositol monophosphatase, putative 0.0036 0.0155 0.0298
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0028 0.009 0.0316
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.0063 0.0381 0.0551
Schistosoma mansoni cellular tumor antigen P53 0.0048 0.0259 0.098
Plasmodium vivax geranylgeranyl transferase type2 beta subunit, putative 0.002 0.0022 0.0017
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.002 0.0018 0.0009
Leishmania major hypothetical protein, conserved 0.0035 0.0146 0.0235
Mycobacterium leprae probable zinc metalloprotease 0.0192 0.1481 1
Plasmodium falciparum polyprenol reductase, putative 0.032 0.2562 1
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.005 0.0275 0.0267
Trypanosoma cruzi major cysteine proteinase, putative 0.0049 0.0265 0.045
Chlamydia trachomatis ATP-dependent Clp protease proteolytic subunit 0.0077 0.0507 0.5
Brugia malayi oxidoreductase 0.002 0.0018 0.0009
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.0035 0.0146 0.0188
Giardia lamblia Rab geranylgeranyltransferase 0.002 0.0022 0.0017
Schistosoma mansoni hypothetical protein 0.0165 0.1253 0.4872
Loa Loa (eye worm) hypothetical protein 0.0023 0.0048 0.0048
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.0063 0.0381 0.1013
Mycobacterium ulcerans extragenic suppressor protein SuhB 0.0036 0.0155 0.0201
Loa Loa (eye worm) hypothetical protein 0.0063 0.0381 0.0381
Loa Loa (eye worm) follicle stimulating hormone receptor 0.0234 0.1838 0.1838
Plasmodium falciparum thioredoxin reductase 0.0037 0.0161 0.0565
Brugia malayi Probable ClpP-like protease 0.0077 0.0507 0.0498
Trichomonas vaginalis short-chain dehydrogenase, putative 0.002 0.0018 0.0025
Trypanosoma cruzi protein farnesyltransferase, putative 0.002 0.0022 0.0008
Echinococcus multilocularis beta LACTamase domain containing family member 0.0035 0.0146 0.0203
Mycobacterium leprae PROBABLE ATP-DEPENDENT CLP PROTEASE PROTEOLYTIC SUBUNIT 2 CLPP2 (ENDOPEPTIDASE CLP 2) 0.0077 0.0507 0.3343
Mycobacterium tuberculosis Conserved protein 0.0035 0.0146 0.0188
Loa Loa (eye worm) aspartic protease BmAsp-2 0.012 0.0864 0.0864
Loa Loa (eye worm) hypothetical protein 0.005 0.0275 0.0275
Schistosoma mansoni nAChR subunit 0.0019 0.0009 0.0003
Brugia malayi Integrin alpha cytoplasmic region family protein 0.0231 0.181 0.1803
Plasmodium vivax 3-oxo-5-alpha-steroid 4-dehydrogenase, putative 0.032 0.2562 1
Echinococcus granulosus geminin 0.0165 0.1253 0.3381
Brugia malayi hypothetical protein 0.0028 0.009 0.0081
Brugia malayi Dehydrogenases, short chain protein 2 0.002 0.0018 0.0009
Leishmania major aldehyde dehydrogenase, mitochondrial precursor 0.0061 0.0366 0.0635
Schistosoma mansoni nAChR subunit (ShAR1-beta-like) 0.0019 0.0009 0.0003
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0063 0.0381 0.1459
Mycobacterium ulcerans hypothetical protein 0.06 0.4937 0.7179
Loa Loa (eye worm) hypothetical protein 0.0063 0.0381 0.0381
Mycobacterium tuberculosis Probable hydrolase 0.0035 0.0146 0.0188
Trichomonas vaginalis AGC family protein kinase 0.0019 0.0009 0.0007
Entamoeba histolytica trans-2,3-enoyl-CoA reductase, putative 0.032 0.2562 0.5182
Loa Loa (eye worm) hypothetical protein 0.0142 0.1055 0.1055
Toxoplasma gondii aspartyl protease 0.0028 0.009 0.0164
Loa Loa (eye worm) integrin beta-2 0.0304 0.2429 0.2429
Trichomonas vaginalis steroid dehydrogenase, putative 0.002 0.0018 0.0025
Loa Loa (eye worm) hypothetical protein 0.0023 0.0048 0.0048
Echinococcus multilocularis glycine receptor subunit alpha 1 0.0019 0.0009 0.0001
Brugia malayi nuclear receptor RXR 0.0033 0.0131 0.0122
Echinococcus multilocularis ephrin type A receptor 4 A 0.0065 0.0397 0.0574
Loa Loa (eye worm) hypothetical protein 0.024 0.1885 0.1885
Echinococcus granulosus acetylcholine receptor subunit beta 1 0.0019 0.0009 0.0002
Echinococcus multilocularis protein farnesyltransferase subunit beta 0.002 0.0022 0.0019
Onchocerca volvulus 0.0047 0.0245 0.0236
Onchocerca volvulus 0.002 0.0018 0.0008
Loa Loa (eye worm) hypothetical protein 0.0019 0.0009 0.0009
Trichomonas vaginalis Clan AA, family A1, cathepsin D-like aspartic peptidase 0.012 0.0864 0.174
Loa Loa (eye worm) hypothetical protein 0.0019 0.0009 0.0009
Entamoeba histolytica estradiol 17-beta-dehydrogenase, putative 0.002 0.0018 0.0018
Schistosoma mansoni serine/threonine protein kinase 0.0035 0.0144 0.0531
Schistosoma mansoni short chain dehydrogenase 0.002 0.0018 0.0034
Echinococcus granulosus acetylcholinesterase 0.0138 0.1021 0.275
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.0063 0.0381 0.1459
Loa Loa (eye worm) AGC/RSK/P70 protein kinase 0.0019 0.0009 0.0009
Plasmodium falciparum plasmepsin III 0.0028 0.009 0.0283
Echinococcus granulosus retinol dehydrogenase 11 0.002 0.0018 0.0024
Brugia malayi Nuclear hormone receptor family member nhr-14 0.0063 0.0381 0.0373
Brugia malayi aspartic protease BmAsp-2, identical 0.0028 0.009 0.0081
Schistosoma mansoni family S9 non-peptidase homologue (S09 family) 0.0138 0.1021 0.3962
Brugia malayi nuclear hormone receptor family member nhr-6 0.003 0.0101 0.0092
Mycobacterium tuberculosis Probable aldehyde dehydrogenase 0.0061 0.0366 0.0508
Brugia malayi Nuclear hormone receptor-like 1 0.0033 0.0131 0.0122
Echinococcus multilocularis Protein kinase C, brain isozyme 0.0121 0.0877 0.1284
Onchocerca volvulus 0.002 0.0018 0.0008
Loa Loa (eye worm) hypothetical protein 0.0032 0.0125 0.0125
Entamoeba histolytica 3-oxo-5-alpha-steroid 4-dehydrogenase domain-containing protein 0.032 0.2562 0.5182
Loa Loa (eye worm) ACC-1 protein 0.0019 0.0009 0.0009
Loa Loa (eye worm) hypothetical protein 0.0077 0.0507 0.0507
Echinococcus granulosus carbonyl reductase 1 0.002 0.0018 0.0024
Echinococcus granulosus ephrin type A receptor 4 A 0.0065 0.0397 0.1056
Toxoplasma gondii eukaryotic aspartyl protease superfamily protein 0.0028 0.009 0.0164
Trypanosoma brucei Sterol methyltransferase, putative 0.0203 0.1573 0.2847
Trichomonas vaginalis short-chain dehydrogenase, putative 0.002 0.0018 0.0025
Schistosoma mansoni short chain dehydrogenase 0.002 0.0018 0.0034
Loa Loa (eye worm) hypothetical protein 0.032 0.2562 0.2562
Brugia malayi latrophilin 2 splice variant baaae 0.0034 0.0141 0.0132
Echinococcus multilocularis zinc finger protein 0.002 0.0016 0.0011
Entamoeba histolytica hypothetical protein 0.002 0.0018 0.0018
Brugia malayi glutathione reductase 0.0037 0.0161 0.0153
Schistosoma mansoni geranylgeranyl transferase type I beta subunit 0.002 0.0022 0.0051
Onchocerca volvulus 0.0035 0.0146 0.0137
Schistosoma mansoni integrin alpha 0.0306 0.2442 0.9528
Trypanosoma cruzi phospholipase A1, putative 0.0667 0.5503 1
Schistosoma mansoni hypothetical protein 0.005 0.0275 0.1045

Activities

Activity type Activity value Assay description Source Reference
Potency (functional) = 35.4813 um PUBCHEM_BIOASSAY: qHTS Assay for Inhibitors and Activators of Human alpha-Glucosidase Cleavage of Glycogen. (Class of assay: confirmatory) [Related pubchem assays: 1473, 1466 ] ChEMBL. No reference
Potency (functional) 100 uM PUBCHEM_BIOASSAY: qHTS for Inhibitors of Polymerase Iota. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID588623] ChEMBL. No reference

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

No literature references available for this target.

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