Detailed information for compound 1349979

Basic information

Technical information
  • TDR Targets ID: 1349979
  • Name: [4-(2-methoxyphenyl)piperazin-1-yl]-(6-methyl -6,7,8,9-tetrahydro-5H-carbazol-3-yl)methanon e
  • MW: 403.517 | Formula: C25H29N3O2
  • H donors: 1 H acceptors: 1 LogP: 4.55 Rotable bonds: 4
    Rule of 5 violations (Lipinski): 1
  • SMILES: COc1ccccc1N1CCN(CC1)C(=O)c1ccc2c(c1)c1CC(C)CCc1[nH]2
  • InChi: 1S/C25H29N3O2/c1-17-7-9-21-19(15-17)20-16-18(8-10-22(20)26-21)25(29)28-13-11-27(12-14-28)23-5-3-4-6-24(23)30-2/h3-6,8,10,16-17,26H,7,9,11-15H2,1-2H3
  • InChiKey: KFTSOQSFJIWFHV-UHFFFAOYSA-N  


Substructure search Similarity search

Network

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Synonyms

  • [4-(2-methoxyphenyl)-1-piperazinyl]-(6-methyl-6,7,8,9-tetrahydro-5H-carbazol-3-yl)methanone
  • T5230119
  • MLS000335042
  • SMR000249800

Targets

Known targets for this compound

Species Target name Source Bibliographic reference
Homo sapiens glycoprotein hormones, alpha polypeptide Starlite/ChEMBL No references
Homo sapiens glucagon-like peptide 1 receptor Starlite/ChEMBL No references
Homo sapiens isocitrate dehydrogenase 1 (NADP+), soluble Starlite/ChEMBL No references
Escherichia coli penicillin-binding protein Starlite/ChEMBL No references
Homo sapiens geminin, DNA replication inhibitor Starlite/ChEMBL No references
Homo sapiens survival of motor neuron 2, centromeric Starlite/ChEMBL No references
Homo sapiens microtubule-associated protein tau Starlite/ChEMBL No references
Homo sapiens multiple endocrine neoplasia I No references
Photinus pyralis Luciferin 4-monooxygenase Starlite/ChEMBL No references
Homo sapiens lysine (K)-specific methyltransferase 2A Starlite/ChEMBL No references
Homo sapiens neuropeptide S receptor 1 Starlite/ChEMBL No references
Homo sapiens euchromatic histone-lysine N-methyltransferase 2 Starlite/ChEMBL No references

Predicted pathogen targets for this compound

By orthology
Species Potential target Known druggable target/s Ortholog Group
Plasmodium falciparum acyl-CoA synthetase Get druggable targets OG5_126609 All targets in OG5_126609
Plasmodium knowlesi isocitrate dehydrogenase [NADP], mitochondrial, putative Get druggable targets OG5_127057 All targets in OG5_127057
Mycobacterium ulcerans hypothetical protein Get druggable targets OG5_126609 All targets in OG5_126609
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_126609 All targets in OG5_126609
Loa Loa (eye worm) isocitrate dehydrogenase Get druggable targets OG5_127057 All targets in OG5_127057
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD7 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) Get druggable targets OG5_126609 All targets in OG5_126609
Brugia malayi hypothetical protein Get druggable targets OG5_132873 All targets in OG5_132873
Leishmania donovani 4-coumarate:coa ligase-like protein Get druggable targets OG5_126609 All targets in OG5_126609
Schistosoma japonicum Menin, putative Get druggable targets OG5_133913 All targets in OG5_133913
Schistosoma mansoni mixed-lineage leukemia protein mll Get druggable targets OG5_130642 All targets in OG5_130642
Brugia malayi isocitrate dehydrogenase Get druggable targets OG5_127057 All targets in OG5_127057
Plasmodium yoelii peroxisomal-coenzyme a synthetase Get druggable targets OG5_126609 All targets in OG5_126609
Neospora caninum hypothetical protein Get druggable targets OG5_127057 All targets in OG5_127057
Mycobacterium tuberculosis Probable chain -fatty-acid-CoA ligase FadD13 (fatty-acyl-CoA synthetase) Get druggable targets OG5_126609 All targets in OG5_126609
Leishmania infantum 4-coumarate:coa ligase-like protein Get druggable targets OG5_126609 All targets in OG5_126609
Toxoplasma gondii isocitrate dehydrogenase Get druggable targets OG5_127057 All targets in OG5_127057
Candida albicans Mitochondrial NADP-specific isocitrate dehydrogenase Get druggable targets OG5_127057 All targets in OG5_127057
Brugia malayi AMP-binding enzyme family protein Get druggable targets OG5_126609 All targets in OG5_126609
Entamoeba histolytica acyl-CoA synthetase, putative Get druggable targets OG5_126609 All targets in OG5_126609
Leishmania braziliensis isocitrate dehydrogenase [NADP], mitochondrial precursor, putative Get druggable targets OG5_127057 All targets in OG5_127057
Plasmodium knowlesi acyl-CoA synthetase, putative Get druggable targets OG5_126609 All targets in OG5_126609
Schistosoma japonicum ko:K04380 microtubule-associated protein tau, putative Get druggable targets OG5_133504 All targets in OG5_133504
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD7 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) Get druggable targets OG5_126609 All targets in OG5_126609
Mycobacterium ulcerans long-chain-fatty-acid--CoA ligase Get druggable targets OG5_126609 All targets in OG5_126609
Onchocerca volvulus Get druggable targets OG5_131470 All targets in OG5_131470
Leishmania major 4-coumarate:coa ligase-like protein Get druggable targets OG5_126609 All targets in OG5_126609
Leishmania mexicana isocitrate dehydrogenase [NADP], mitochondrial precursor, putative Get druggable targets OG5_127057 All targets in OG5_127057
Plasmodium berghei acyl-CoA synthetase, putative Get druggable targets OG5_126609 All targets in OG5_126609
Loa Loa (eye worm) pre-SET domain-containing protein family protein Get druggable targets OG5_131470 All targets in OG5_131470
Leishmania donovani isocitrate dehydrogenase [NADP], mitochondrial precursor, putative Get druggable targets OG5_127057 All targets in OG5_127057
Plasmodium yoelii isocitrate dehydrogenase, NADP-dependent Get druggable targets OG5_127057 All targets in OG5_127057
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD2 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) Get druggable targets OG5_126609 All targets in OG5_126609
Leishmania donovani 4-coumarate:coa ligase-like protein Get druggable targets OG5_126609 All targets in OG5_126609
Mycobacterium tuberculosis Fatty-acid-AMP ligase FadD30 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) Get druggable targets OG5_126609 All targets in OG5_126609
Echinococcus multilocularis dnaJ subfamily B Get druggable targets OG5_133913 All targets in OG5_133913
Schistosoma mansoni hypothetical protein Get druggable targets OG5_133913 All targets in OG5_133913
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_126609 All targets in OG5_126609
Leishmania braziliensis 4-coumarate:coa ligase-like protein Get druggable targets OG5_126609 All targets in OG5_126609
Plasmodium falciparum isocitrate dehydrogenase [NADP], mitochondrial Get druggable targets OG5_127057 All targets in OG5_127057
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase Get druggable targets OG5_127057 All targets in OG5_127057
Echinococcus multilocularis neuropeptide s receptor Get druggable targets OG5_136011 All targets in OG5_136011
Leishmania mexicana 4-coumarate:coa ligase-like protein Get druggable targets OG5_126609 All targets in OG5_126609
Mycobacterium ulcerans long-chain fatty-acid CoA ligase Get druggable targets OG5_126609 All targets in OG5_126609
Trypanosoma congolense isocitrate dehydrogenase, putative Get druggable targets OG5_127057 All targets in OG5_127057
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase Get druggable targets OG5_127057 All targets in OG5_127057
Theileria parva isocitrate dehydrogenase (NADP+), putative Get druggable targets OG5_127057 All targets in OG5_127057
Neospora caninum Multidomain chromatinic protein with the following architecture: 3x PHD-bromo-3xPHD-SET domain and associated cysteine cluster a Get druggable targets OG5_130642 All targets in OG5_130642
Candida albicans N terminus of cytosolic NADP-specific isocitrate dehydrogenase. Get druggable targets OG5_127057 All targets in OG5_127057
Brugia malayi Isocitrate dehydrogenase Get druggable targets OG5_127057 All targets in OG5_127057
Plasmodium yoelii isocitrate dehydrogenase, NADP-dependent, putative Get druggable targets OG5_127057 All targets in OG5_127057
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_126609 All targets in OG5_126609
Leishmania mexicana 4-coumarate:coa ligase-like protein Get druggable targets OG5_126609 All targets in OG5_126609
Trypanosoma brucei isocitrate dehydrogenase, putative Get druggable targets OG5_127057 All targets in OG5_127057
Leishmania mexicana 4-coumarate:coa ligase-like protein Get druggable targets OG5_126609 All targets in OG5_126609
Leishmania major 4-coumarate:coa ligase-like protein Get druggable targets OG5_126609 All targets in OG5_126609
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD35 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) Get druggable targets OG5_126609 All targets in OG5_126609
Plasmodium vivax acyl-CoA synthetase, putative Get druggable targets OG5_126609 All targets in OG5_126609
Trypanosoma congolense isocitrate dehydrogenase, putative Get druggable targets OG5_127057 All targets in OG5_127057
Leishmania infantum 4-coumarate:coa ligase-like protein Get druggable targets OG5_126609 All targets in OG5_126609
Neospora caninum Isocitrate dehydrogenase-like protein, related Get druggable targets OG5_127057 All targets in OG5_127057
Mycobacterium ulcerans long-chain-fatty-acid-CoA ligase Get druggable targets OG5_126609 All targets in OG5_126609
Plasmodium berghei isocitrate dehydrogenase [NADP], mitochondrial, putative Get druggable targets OG5_127057 All targets in OG5_127057
Leishmania major isocitrate dehydrogenase [NADP], mitochondrial precursor, putative Get druggable targets OG5_127057 All targets in OG5_127057
Leishmania infantum 4-coumarate:coa ligase-like protein Get druggable targets OG5_126609 All targets in OG5_126609
Echinococcus granulosus neuropeptide s receptor Get druggable targets OG5_136011 All targets in OG5_136011
Trypanosoma brucei gambiense isocitrate dehydrogenase [NADP], mitochondrial precursor, putative Get druggable targets OG5_127057 All targets in OG5_127057
Trypanosoma cruzi isocitrate dehydrogenase, putative Get druggable targets OG5_127057 All targets in OG5_127057
Echinococcus multilocularis microtubule associated protein 2 Get druggable targets OG5_133504 All targets in OG5_133504
Entamoeba histolytica acyl-coA synthetase, putative Get druggable targets OG5_126609 All targets in OG5_126609
Brugia malayi Pre-SET motif family protein Get druggable targets OG5_131470 All targets in OG5_131470
Echinococcus granulosus survival motor neuron protein 1 Get druggable targets OG5_132873 All targets in OG5_132873
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_126609 All targets in OG5_126609
Schistosoma japonicum ko:K00031 isocitrate dehydrogenase [EC1.1.1.42], putative Get druggable targets OG5_127057 All targets in OG5_127057
Plasmodium vivax isocitrate dehydrogenase [NADP], mitochondrial, putative Get druggable targets OG5_127057 All targets in OG5_127057
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_126609 All targets in OG5_126609
Echinococcus multilocularis isocitrate dehydrogenase 2 (NADP+) Get druggable targets OG5_127057 All targets in OG5_127057
Mycobacterium ulcerans fatty-acid-CoA ligase Get druggable targets OG5_126609 All targets in OG5_126609
Brugia malayi AMP-binding enzyme family protein Get druggable targets OG5_126609 All targets in OG5_126609
Echinococcus multilocularis neuropeptide receptor A26 Get druggable targets OG5_136011 All targets in OG5_136011
Candida albicans C terminus of cytosolic NADP-specific isocitrate dehydrogenase. Get druggable targets OG5_127057 All targets in OG5_127057
Trypanosoma cruzi isocitrate dehydrogenase [NADP], mitochondrial precursor, putative Get druggable targets OG5_127057 All targets in OG5_127057
Mycobacterium tuberculosis Possible penicillin-binding protein Get druggable targets OG5_149948 All targets in OG5_149948
Mycobacterium tuberculosis Probable isocitrate dehydrogenase [NADP] Icd1 (oxalosuccinate decarboxylase) (IDH) (NADP+-specific ICDH) (IDP) Get druggable targets OG5_127057 All targets in OG5_127057
Leishmania infantum isocitrate dehydrogenase [NADP], mitochondrial precursor, putative Get druggable targets OG5_127057 All targets in OG5_127057
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase Get druggable targets OG5_127057 All targets in OG5_127057
Trypanosoma brucei gambiense isocitrate dehydrogenase, putative Get druggable targets OG5_127057 All targets in OG5_127057
Trypanosoma brucei isocitrate dehydrogenase [NADP], mitochondrial precursor, putative Get druggable targets OG5_127057 All targets in OG5_127057
Leishmania infantum 4-coumarate:coa ligase-like protein Get druggable targets OG5_126609 All targets in OG5_126609
Candida albicans Mitochondrial NADP-specific isocitrate dehydrogenase Get druggable targets OG5_127057 All targets in OG5_127057
Mycobacterium ulcerans acyl-CoA synthetase Get druggable targets OG5_126609 All targets in OG5_126609
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD2 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) Get druggable targets OG5_126609 All targets in OG5_126609
Echinococcus granulosus neuropeptide receptor A26 Get druggable targets OG5_136011 All targets in OG5_136011
Schistosoma mansoni NADP-specific isocitrate dehydrogenase Get druggable targets OG5_127057 All targets in OG5_127057
Echinococcus multilocularis survival motor neuron protein 1 Get druggable targets OG5_132873 All targets in OG5_132873
Echinococcus granulosus dnaJ subfamily B Get druggable targets OG5_133913 All targets in OG5_133913
Toxoplasma gondii histone lysine methyltransferase SET1 Get druggable targets OG5_130642 All targets in OG5_130642
Mycobacterium ulcerans acyl-CoA synthetase Get druggable targets OG5_126609 All targets in OG5_126609
Babesia bovis isocitrate dehydrogenase, NADP-dependent family protein Get druggable targets OG5_127057 All targets in OG5_127057
Brugia malayi AMP-binding enzyme family protein Get druggable targets OG5_126609 All targets in OG5_126609
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD3 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) Get druggable targets OG5_126609 All targets in OG5_126609
Entamoeba histolytica acyl-CoA synthetase, putative Get druggable targets OG5_126609 All targets in OG5_126609
Echinococcus multilocularis isocitrate dehydrogenase Get druggable targets OG5_127057 All targets in OG5_127057
Chlamydia trachomatis acylglycerophosphoethanolamine acyltransferase Get druggable targets OG5_126609 All targets in OG5_126609
Schistosoma mansoni microtubule-associated protein tau Get druggable targets OG5_133504 All targets in OG5_133504
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_132873 All targets in OG5_132873
Toxoplasma gondii isocitrate dehydrogenase Get druggable targets OG5_127057 All targets in OG5_127057
Echinococcus granulosus NADP dependent isocitrate dehydrogenase Get druggable targets OG5_127057 All targets in OG5_127057
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_126609 All targets in OG5_126609
Trichomonas vaginalis set domain proteins, putative Get druggable targets OG5_131470 All targets in OG5_131470
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_126609 All targets in OG5_126609
Mycobacterium ulcerans fatty-acid-CoA ligase Get druggable targets OG5_126609 All targets in OG5_126609
Onchocerca volvulus Get druggable targets OG5_126609 All targets in OG5_126609
Schistosoma japonicum IPR000276,Rhodopsin-like GPCR superfamily,domain-containing Get druggable targets OG5_136011 All targets in OG5_136011
Schistosoma japonicum ko:K09188 myeloid/lymphoid or mixed-lineage leukemia protein 3, putative Get druggable targets OG5_130642 All targets in OG5_130642
Leishmania major 4-coumarate:coa ligase-like protein Get druggable targets OG5_126609 All targets in OG5_126609
Mycobacterium ulcerans acyl-CoA synthetase Get druggable targets OG5_126609 All targets in OG5_126609
Candida albicans cytosolic NADP-specific isocitrate dehydrogenase. Get druggable targets OG5_127057 All targets in OG5_127057
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_126609 All targets in OG5_126609
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD5 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) Get druggable targets OG5_126609 All targets in OG5_126609
Echinococcus granulosus microtubule associated protein 2 Get druggable targets OG5_133504 All targets in OG5_133504
By sequence similarity to non orthologous known druggable targets
Species Potential target Known druggable target Length Alignment span Identity
Neospora caninum Short-chain dehydrogenase/reductase SDR, related Luciferin 4-monooxygenase   550 aa 518 aa 19.1 %
Dictyostelium discoideum AMP-dependent synthetase and ligase domain-containing protein Luciferin 4-monooxygenase   550 aa 517 aa 24.8 %
Leishmania major long chain fatty Acyl CoA synthetase, putative Luciferin 4-monooxygenase   550 aa 482 aa 23.2 %
Mycobacterium tuberculosis Fatty-acid-AMP ligase FadD28 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) Luciferin 4-monooxygenase   550 aa 504 aa 22.6 %
Candida albicans similar to S. cerevisiae FAA4 (YMR246W) long-chain fatty acid--CoA synthetase Luciferin 4-monooxygenase   550 aa 478 aa 23.4 %
Mycobacterium ulcerans non-ribosomal peptide synthetase MbtF Luciferin 4-monooxygenase   550 aa 558 aa 20.1 %
Cryptosporidium hominis acyl-CoA synthetase Luciferin 4-monooxygenase   550 aa 460 aa 26.1 %
Mycobacterium leprae PROBABLE FATTY-ACID--CoA LIGASE FADD21 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) Luciferin 4-monooxygenase   550 aa 565 aa 22.8 %
Mycobacterium ulcerans long-chain-fatty-acid-CoA ligase, FadD11 Luciferin 4-monooxygenase   550 aa 492 aa 24.6 %
Dictyostelium discoideum acetyl-CoA ligase Luciferin 4-monooxygenase   550 aa 549 aa 22.2 %
Mycobacterium ulcerans acyl-CoA synthetase Luciferin 4-monooxygenase   550 aa 530 aa 23.8 %
Trypanosoma brucei fatty acyl CoA synthetase 3 Luciferin 4-monooxygenase   550 aa 491 aa 23.6 %
Leishmania infantum long chain fatty Acyl CoA synthetase, putative Luciferin 4-monooxygenase   550 aa 500 aa 23.4 %
Candida albicans similar to S. cerevisiae FAT1 (YBR041W) fatty acid transporter and very long-chain fatty acyl-CoA synthetase Luciferin 4-monooxygenase   550 aa 496 aa 24.2 %
Neospora caninum acetyl-coenzyme a synthetase, putative Luciferin 4-monooxygenase   550 aa 549 aa 20.9 %
Leishmania braziliensis long-chain-fatty-acid-CoA ligase, putative Luciferin 4-monooxygenase   550 aa 504 aa 25.6 %
Cryptosporidium hominis acetyl-CoenzymeA synthetase (acetate--coa ligase) (acyl-activating enzyme) Luciferin 4-monooxygenase   550 aa 549 aa 22.6 %
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein Luciferin 4-monooxygenase   550 aa 476 aa 22.5 %
Mycobacterium ulcerans acyl-CoA synthetase Luciferin 4-monooxygenase   550 aa 582 aa 22.3 %
Trypanosoma congolense fatty acyl CoA synthetase 2, putative Luciferin 4-monooxygenase   550 aa 500 aa 22.4 %
Dictyostelium discoideum hypothetical protein Luciferin 4-monooxygenase   550 aa 542 aa 22.1 %
Mycobacterium leprae Probable fatty-acid-CoA synthetase FadD29 (fatty-acid-CoA ligase) (fatty-acid-CoA synthase) Luciferin 4-monooxygenase   550 aa 529 aa 22.3 %
Trichomonas vaginalis AMP dependent CoA ligase, putative Luciferin 4-monooxygenase   550 aa 527 aa 25.0 %
Schistosoma mansoni FAA1 Long-chain-fatty-acid--CoA ligase 1 Luciferin 4-monooxygenase   550 aa 494 aa 26.3 %
Dictyostelium discoideum hypothetical protein Luciferin 4-monooxygenase   550 aa 541 aa 21.6 %
Onchocerca volvulus Matrilysin homolog Luciferin 4-monooxygenase   550 aa 466 aa 24.2 %
Mycobacterium leprae Probable fatty-acid-CoA synthetase FadD22 (fatty-acid-CoA ligase) (fatty-acid-CoA synthase) Luciferin 4-monooxygenase   550 aa 493 aa 20.7 %
Candida albicans similar to S. cerevisiae ACS2 (YLR153C) acetyl-CoA synthetase Luciferin 4-monooxygenase   550 aa 539 aa 22.1 %
Echinococcus multilocularis long chain fatty acid coenzyme A ligase 5 Luciferin 4-monooxygenase   550 aa 458 aa 25.5 %
Echinococcus multilocularis long chain fatty acid coenzyme A ligase 1 Luciferin 4-monooxygenase   550 aa 459 aa 27.0 %
Brugia malayi Hypothetical 65.5 kDa Trp-Asp repeats containing protein F02E8.5 inchromosome X geminin, DNA replication inhibitor 209 aa 176 aa 27.8 %
Entamoeba histolytica acyl-CoA synthetase, putative Luciferin 4-monooxygenase   550 aa 446 aa 22.0 %
Dictyostelium discoideum hypothetical protein Luciferin 4-monooxygenase   550 aa 541 aa 21.4 %
Dictyostelium discoideum AMP-dependent synthetase and ligase domain-containing protein Luciferin 4-monooxygenase   550 aa 545 aa 24.9 %
Mycobacterium ulcerans fatty-acid-CoA ligase FadD9 Luciferin 4-monooxygenase   550 aa 463 aa 21.8 %
Mycobacterium leprae Probable fatty-acid-CoA synthetase FadD32 (fatty-acid-CoA ligase) (fatty-acid-CoA synthase) Luciferin 4-monooxygenase   550 aa 442 aa 23.5 %
Onchocerca volvulus Luciferin 4-monooxygenase   550 aa 487 aa 23.8 %
Trichomonas vaginalis antibiotic synthetase, putative Luciferin 4-monooxygenase   550 aa 577 aa 22.2 %
Toxoplasma gondii type I fatty acid synthase, putative Luciferin 4-monooxygenase   550 aa 514 aa 19.8 %
Mycobacterium tuberculosis Probable fatty-acid-AMP ligase FadD23 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) Luciferin 4-monooxygenase   550 aa 542 aa 23.8 %
Cryptosporidium parvum acyl-CoA synthetase Luciferin 4-monooxygenase   550 aa 460 aa 25.7 %
Leishmania donovani long chain fatty Acyl CoA synthetase, putative Luciferin 4-monooxygenase   550 aa 500 aa 23.4 %
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD8 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) Luciferin 4-monooxygenase   550 aa 505 aa 28.1 %
Trichomonas vaginalis AMP dependent ligase/synthetase, putative Luciferin 4-monooxygenase   550 aa 494 aa 24.3 %
Dictyostelium discoideum hypothetical protein Luciferin 4-monooxygenase   550 aa 542 aa 18.3 %
Trichomonas vaginalis AMP dependent ligase/synthetase, putative Luciferin 4-monooxygenase   550 aa 554 aa 24.4 %
Leishmania mexicana long chain fatty Acyl CoA synthetase, putative Luciferin 4-monooxygenase   550 aa 483 aa 23.8 %
Dictyostelium discoideum hypothetical protein Luciferin 4-monooxygenase   550 aa 538 aa 21.8 %
Babesia bovis long-chain acyl-CoA synthetase, putative Luciferin 4-monooxygenase   550 aa 445 aa 21.8 %
Dictyostelium discoideum fatty acyl-CoA synthetase Luciferin 4-monooxygenase   550 aa 501 aa 24.4 %
Babesia bovis fatty acyl-CoA synthetase family protein Luciferin 4-monooxygenase   550 aa 461 aa 23.4 %
Trypanosoma cruzi fatty acyl CoA synthetase 2, putative Luciferin 4-monooxygenase   550 aa 495 aa 22.6 %
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD9 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) Luciferin 4-monooxygenase   550 aa 480 aa 22.5 %
Entamoeba histolytica long-chain-fatty-acid--CoA ligase, putative Luciferin 4-monooxygenase   550 aa 494 aa 23.9 %
Entamoeba histolytica long-chain-fatty-acid--CoA ligase, putative Luciferin 4-monooxygenase   550 aa 480 aa 21.5 %
Brugia malayi AMP-binding enzyme family protein Luciferin 4-monooxygenase   550 aa 497 aa 24.7 %
Echinococcus granulosus long chain fatty acid coenzyme A ligase 5 Luciferin 4-monooxygenase   550 aa 458 aa 25.8 %
Trypanosoma cruzi fatty acyl CoA synthetase, putative Luciferin 4-monooxygenase   550 aa 480 aa 25.2 %
Onchocerca volvulus Lysine-specific histone demethylase 1A homolog Luciferin 4-monooxygenase   550 aa 550 aa 22.5 %
Trichomonas vaginalis AMP dependent ligase/synthetase, putative Luciferin 4-monooxygenase   550 aa 526 aa 22.4 %
Trichomonas vaginalis AMP dependent CoA ligase, putative Luciferin 4-monooxygenase   550 aa 524 aa 24.0 %
Mycobacterium ulcerans non-ribosomal peptide synthetase Luciferin 4-monooxygenase   550 aa 541 aa 22.4 %
Mycobacterium leprae FATTY-ACID-CoA LIGASE FADD26 (FATTY-ACID-COA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) Luciferin 4-monooxygenase   550 aa 533 aa 22.7 %
Mycobacterium tuberculosis Fatty-acid-AMP ligase FadD29 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) Luciferin 4-monooxygenase   550 aa 617 aa 22.2 %
Mycobacterium ulcerans fatty-acid-CoA ligase FadD11 Luciferin 4-monooxygenase   550 aa 498 aa 23.5 %
Schistosoma japonicum ko:K01897 long-chain fatty-acid-CoA ligase [EC6.2.1.3], putative Luciferin 4-monooxygenase   550 aa 541 aa 22.4 %
Dictyostelium discoideum AMP-dependent synthetase and ligase domain-containing protein Luciferin 4-monooxygenase   550 aa 531 aa 19.0 %
Leishmania mexicana acetyl-CoA synthetase, putative Luciferin 4-monooxygenase   550 aa 559 aa 20.6 %
Schistosoma japonicum ko:K01897 long-chain fatty-acid-CoA ligase [EC6.2.1.3], putative Luciferin 4-monooxygenase   550 aa 466 aa 27.3 %
Schistosoma japonicum ko:K08745 solute carrier family 27 (fatty acid transporter), member 1, putative Luciferin 4-monooxygenase   550 aa 501 aa 24.6 %
Echinococcus multilocularis long chain fatty acid transport protein 4 Luciferin 4-monooxygenase   550 aa 476 aa 22.3 %
Dictyostelium discoideum hypothetical protein Luciferin 4-monooxygenase   550 aa 576 aa 19.8 %
Trypanosoma cruzi fatty acyl CoA synthetase, putative Luciferin 4-monooxygenase   550 aa 482 aa 24.7 %
Entamoeba histolytica long-chain-fatty-acid--CoA ligase, putative Luciferin 4-monooxygenase   550 aa 476 aa 20.8 %
Dictyostelium discoideum hypothetical protein Luciferin 4-monooxygenase   550 aa 478 aa 21.1 %
Mycobacterium ulcerans peptide synthetase Nrp (peptide synthase) Luciferin 4-monooxygenase   550 aa 535 aa 23.2 %
Trichomonas vaginalis AMP dependent CoA ligase, putative Luciferin 4-monooxygenase   550 aa 492 aa 23.6 %
Cryptosporidium parvum acetyl-coenzyme A synthetase Luciferin 4-monooxygenase   550 aa 545 aa 22.8 %
Leishmania braziliensis long chain fatty Acyl CoA synthetase, putative Luciferin 4-monooxygenase   550 aa 496 aa 22.8 %
Leishmania braziliensis acetyl-CoA synthetase, putative Luciferin 4-monooxygenase   550 aa 603 aa 22.6 %
Mycobacterium ulcerans non-ribosomal peptide synthetase MbtE Luciferin 4-monooxygenase   550 aa 502 aa 22.5 %
Toxoplasma gondii propionate-CoA ligase Luciferin 4-monooxygenase   550 aa 550 aa 21.1 %
Trichomonas vaginalis long-chain-fatty-acid CoA ligase, putative Luciferin 4-monooxygenase   550 aa 490 aa 23.3 %
Mycobacterium leprae Probable long-chain-fatty-acid-CoA ligase FadD15 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) Luciferin 4-monooxygenase   550 aa 484 aa 23.3 %
Dictyostelium discoideum hypothetical protein Luciferin 4-monooxygenase   550 aa 558 aa 20.4 %
Mycobacterium tuberculosis Probable peptide synthetase Nrp (peptide synthase) Luciferin 4-monooxygenase   550 aa 509 aa 22.6 %
Dictyostelium discoideum hypothetical protein Luciferin 4-monooxygenase   550 aa 522 aa 19.9 %
Loa Loa (eye worm) AMP-binding enzyme family protein Luciferin 4-monooxygenase   550 aa 489 aa 23.3 %
Echinococcus granulosus long chain fatty acid coenzyme A ligase 1 Luciferin 4-monooxygenase   550 aa 452 aa 26.1 %
Toxoplasma gondii intraflagellar transport protein 172, putative glycoprotein hormones, alpha polypeptide 116 aa 94 aa 26.6 %
Mycobacterium tuberculosis Probable acyl-CoA ligase FadD31 (acyl-CoA synthetase) (acyl-CoA synthase) Luciferin 4-monooxygenase   550 aa 592 aa 20.4 %
Mycobacterium leprae Probable fatty-acid-CoA synthetase FadD28 (fatty-acid-CoA ligase) (fatty-acid-CoA synthase) Luciferin 4-monooxygenase   550 aa 484 aa 20.5 %
Candida albicans similar to S. cerevisiae FAT1 (YBR041W) fatty acid transporter and very long-chain fatty acyl-CoA synthetase Luciferin 4-monooxygenase   550 aa 496 aa 24.2 %
Echinococcus granulosus long chain fatty acid transport protein 4 Luciferin 4-monooxygenase   550 aa 476 aa 22.3 %
Dictyostelium discoideum AMP-dependent synthetase and ligase domain-containing protein Luciferin 4-monooxygenase   550 aa 550 aa 20.9 %
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD34 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) Luciferin 4-monooxygenase   550 aa 537 aa 20.9 %
Candida albicans similar to S. cerevisiae ACS2 (YLR153C) acetyl-CoA synthetase Luciferin 4-monooxygenase   550 aa 539 aa 22.1 %
Trichomonas vaginalis antibiotic synthetase, putative Luciferin 4-monooxygenase   550 aa 581 aa 21.2 %
Mycobacterium ulcerans long-chain-fatty-acid-CoA ligase FadD15 Luciferin 4-monooxygenase   550 aa 482 aa 24.3 %
Mycobacterium tuberculosis P-hydroxybenzoyl-AMP ligase FadD22 Luciferin 4-monooxygenase   550 aa 493 aa 22.1 %
Dictyostelium discoideum hypothetical protein Luciferin 4-monooxygenase   550 aa 542 aa 22.1 %
Leishmania braziliensis acetyl-CoA synthetase, putative Luciferin 4-monooxygenase   550 aa 596 aa 21.1 %
Trichomonas vaginalis AMP dependent ligase/synthetase, putative Luciferin 4-monooxygenase   550 aa 476 aa 23.5 %
Candida albicans similar to S. cerevisiae ACS2 (YLR153C) acetyl-CoA synthetase Luciferin 4-monooxygenase   550 aa 543 aa 24.5 %
Trichomonas vaginalis long-chain-fatty-acid CoA ligase, putative Luciferin 4-monooxygenase   550 aa 466 aa 21.7 %
Dictyostelium discoideum hypothetical protein Luciferin 4-monooxygenase   550 aa 463 aa 23.5 %
Mycobacterium ulcerans acyl-CoA synthetase Luciferin 4-monooxygenase   550 aa 601 aa 22.5 %
Mycobacterium ulcerans acyl-CoA synthetase Luciferin 4-monooxygenase   550 aa 497 aa 19.3 %
Mycobacterium tuberculosis Fatty-acid-AMP ligase FadD32 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase). Also shown to have acyl-ACP ligase activity. Luciferin 4-monooxygenase   550 aa 487 aa 22.4 %
Dictyostelium discoideum hypothetical protein Luciferin 4-monooxygenase   550 aa 539 aa 19.1 %
Theileria parva long-chain fatty acid CoA ligase, putative Luciferin 4-monooxygenase   550 aa 507 aa 23.5 %
Cryptosporidium parvum putative long chain fatty acyl CoA synthetase having a signal peptide Luciferin 4-monooxygenase   550 aa 472 aa 24.8 %
Dictyostelium discoideum hypothetical protein Luciferin 4-monooxygenase   550 aa 522 aa 19.9 %
Mycobacterium tuberculosis Probable fatty-acid-AMP ligase FadD25 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) Luciferin 4-monooxygenase   550 aa 475 aa 21.1 %
Dictyostelium discoideum hypothetical protein Luciferin 4-monooxygenase   550 aa 539 aa 19.1 %
Brugia malayi AMP-binding enzyme family protein Luciferin 4-monooxygenase   550 aa 544 aa 21.5 %
Mycobacterium leprae Probable fatty-acid-CoA ligase FadD9 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) Luciferin 4-monooxygenase   550 aa 461 aa 22.3 %
Trichomonas vaginalis AMP dependent ligase/synthetase, putative Luciferin 4-monooxygenase   550 aa 554 aa 22.9 %
Dictyostelium discoideum hypothetical protein Luciferin 4-monooxygenase   550 aa 541 aa 21.4 %
Candida albicans similar to S. cerevisiae ACS2 (YLR153C) acetyl-CoA synthetase Luciferin 4-monooxygenase   550 aa 543 aa 24.5 %
Dictyostelium discoideum hypothetical protein Luciferin 4-monooxygenase   550 aa 538 aa 21.8 %
Mycobacterium tuberculosis Probable fatty-acid-AMP ligase FadD24 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) Luciferin 4-monooxygenase   550 aa 526 aa 21.9 %
Dictyostelium discoideum hypothetical protein Luciferin 4-monooxygenase   550 aa 535 aa 21.7 %
Trichomonas vaginalis AMP dependent ligase, putative Luciferin 4-monooxygenase   550 aa 445 aa 26.1 %
Loa Loa (eye worm) pigment dispersing factor receptor c glucagon-like peptide 1 receptor 463 aa 388 aa 25.8 %
Dictyostelium discoideum hypothetical protein Luciferin 4-monooxygenase   550 aa 499 aa 19.2 %
Trypanosoma brucei gambiense fatty acyl CoA synthetase 4, putative Luciferin 4-monooxygenase   550 aa 497 aa 23.7 %
Dictyostelium discoideum hypothetical protein Luciferin 4-monooxygenase   550 aa 507 aa 20.9 %
Echinococcus multilocularis long chain fatty acid coenzyme A ligase 1 Luciferin 4-monooxygenase   550 aa 443 aa 26.4 %
Dictyostelium discoideum hypothetical protein Luciferin 4-monooxygenase   550 aa 535 aa 22.6 %
Mycobacterium ulcerans putative fatty-acid--CoA ligase Luciferin 4-monooxygenase   550 aa 576 aa 20.8 %
Mycobacterium ulcerans acyl-CoA synthetase Luciferin 4-monooxygenase   550 aa 593 aa 22.1 %
Dictyostelium discoideum hypothetical protein Luciferin 4-monooxygenase   550 aa 542 aa 18.3 %
Mycobacterium ulcerans long-chain-fatty-acid-CoA ligase FadD15 Luciferin 4-monooxygenase   550 aa 484 aa 26.0 %
Mycobacterium tuberculosis Probable fatty-acid-AMP ligase FadD21 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) Luciferin 4-monooxygenase   550 aa 586 aa 24.4 %
Mycobacterium ulcerans long-chain-fatty-acid--CoA ligase Luciferin 4-monooxygenase   550 aa 509 aa 21.8 %
Dictyostelium discoideum fatty acyl-CoA synthetase Luciferin 4-monooxygenase   550 aa 462 aa 23.8 %
Dictyostelium discoideum hypothetical protein Luciferin 4-monooxygenase   550 aa 541 aa 21.6 %
Trypanosoma brucei gambiense fatty acyl CoA synthetase 3 Luciferin 4-monooxygenase   550 aa 491 aa 23.6 %
Onchocerca volvulus Luciferin 4-monooxygenase   550 aa 502 aa 24.9 %
Mycobacterium tuberculosis Fatty-acid-AMP ligase FadD26 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) Luciferin 4-monooxygenase   550 aa 560 aa 21.4 %
Mycobacterium tuberculosis Bifunctional enzyme MbtA: salicyl-AMP ligase (SAL-AMP ligase) + salicyl-S-ArCP synthetase Luciferin 4-monooxygenase   550 aa 536 aa 24.4 %
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Loa Loa (eye worm) cytochrome P450 0.0022 0.0083 0.0097
Schistosoma mansoni peroxidasin 0.0173 0.1897 0.1929
Echinococcus multilocularis neurogenic locus protein delta 0.0017 0.0027 0.0027
Onchocerca volvulus 0.0018 0.0036 0.0079
Loa Loa (eye worm) hypothetical protein 0.0017 0.0027 0.0031
Mycobacterium tuberculosis Probable lipase LipE 0.0073 0.0697 0.0652
Brugia malayi GCC2 and GCC3 family protein 0.0017 0.0027 0.0031
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0145 0.1565 0.4725
Echinococcus granulosus cathepsin l1 0.0145 0.1565 0.1591
Schistosoma mansoni dipeptidyl-peptidase 9 (S09 family) 0.0041 0.0316 0.0321
Brugia malayi EGF-like domain containing protein 0.0017 0.0027 0.0031
Toxoplasma gondii centrin 0.0018 0.004 0.0031
Entamoeba histolytica cysteine protease, putative 0.0037 0.0261 0.1448
Giardia lamblia Cathepsin B precursor 0.0037 0.0261 0.1387
Toxoplasma gondii HEAT repeat-containing protein 0.0029 0.0166 0.0309
Schistosoma mansoni smad 0.0033 0.0222 0.0226
Brugia malayi Papain family cysteine protease containing protein 0.0081 0.079 0.0918
Schistosoma mansoni hypothetical protein 0.0017 0.0027 0.0027
Echinococcus granulosus multidrug resistance protein 1 0.0044 0.0344 0.035
Mycobacterium ulcerans acyl-CoA synthetase 0.0029 0.0165 0.0129
Schistosoma mansoni cercarial elastase (S01 family) 0.0018 0.0036 0.0036
Loa Loa (eye worm) hypothetical protein 0.0019 0.0049 0.0057
Echinococcus multilocularis neurogenic locus notch protein 0.0017 0.0027 0.0027
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0073 0.0697 0.0708
Echinococcus multilocularis cathepsin b 0.0428 0.4971 0.5053
Trypanosoma cruzi oligopeptidase b 0.0156 0.17 0.3365
Brugia malayi cathepsin F-like cysteine proteinase 0.0037 0.0261 0.0304
Trichomonas vaginalis CMGC family protein kinase 0.0049 0.0415 0.116
Trichomonas vaginalis multidrug resistance protein 1, 2, putative 0.0044 0.0344 0.094
Echinococcus granulosus calmodulin 0.0018 0.004 0.0041
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0125 0.1319 0.2593
Entamoeba histolytica cysteine protease, putative 0.0081 0.079 0.4915
Mycobacterium ulcerans protease II (oligopeptidase B), PtrB 0.0156 0.17 0.167
Onchocerca volvulus 0.0101 0.1033 0.2272
Loa Loa (eye worm) hypothetical protein 0.0041 0.0315 0.0366
Loa Loa (eye worm) blistered cuticle protein 3 0.0173 0.1897 0.2205
Loa Loa (eye worm) hypothetical protein 0.0018 0.0036 0.0041
Leishmania major apurinic/apyrimidinic endonuclease-redox protein 0.0019 0.0048 0.0017
Trichomonas vaginalis conserved hypothetical protein 0.0037 0.0271 0.0714
Mycobacterium ulcerans lipase LipD 0.0073 0.0697 0.0664
Echinococcus multilocularis dnaJ subfamily B 0.0494 0.5758 0.5853
Mycobacterium tuberculosis Probable cytochrome P450 138 Cyp138 0.0022 0.0083 0.0035
Brugia malayi Animal haem peroxidase family protein 0.0173 0.1897 0.2205
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0145 0.1565 0.4725
Plasmodium falciparum serine repeat antigen 5 0.0037 0.0261 0.1117
Echinococcus granulosus EF hand domain containing family member A2 0.0018 0.004 0.0041
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD2 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0029 0.0165 0.0117
Loa Loa (eye worm) hypothetical protein 0.0021 0.0078 0.009
Echinococcus multilocularis ATP binding cassette subfamily B (MDR:TAP) 0.0044 0.0344 0.035
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0037 0.0261 0.0684
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.0081 0.079 0.0803
Trypanosoma cruzi mitogen activated protein kinase 4, putative 0.0049 0.0415 0.0759
Trichomonas vaginalis ATP-binding cassette transporter, putative 0.0044 0.0344 0.094
Entamoeba histolytica cysteine proteinase, putative 0.0081 0.079 0.4915
Onchocerca volvulus Cathepsin F homolog 0.0145 0.1565 0.3443
Onchocerca volvulus 0.0287 0.3268 0.7188
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.0073 0.0697 0.0652
Giardia lamblia Dipeptidyl-peptidase I precursor 0.0037 0.0261 0.1387
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0428 0.4971 0.5053
Echinococcus multilocularis tumor protein p63 0.0689 0.8103 0.8237
Mycobacterium tuberculosis Possible penicillin-binding protein 0.0466 0.542 0.5398
Loa Loa (eye worm) hypothetical protein 0.0173 0.1897 0.2205
Onchocerca volvulus Peroxidasin homolog 0.0173 0.1897 0.4173
Brugia malayi Cathepsin L-like precursor 0.0145 0.1565 0.1819
Loa Loa (eye worm) EF hand family protein 0.0018 0.004 0.0047
Toxoplasma gondii aspartyl protease ASP1 0.0023 0.0093 0.0146
Entamoeba histolytica prolyl oligopeptidase family protein 0.0041 0.0316 0.1808
Onchocerca volvulus 0.011 0.1143 0.2515
Schistosoma mansoni hypothetical protein 0.0017 0.0027 0.0027
Entamoeba histolytica cysteine protease, putative 0.0081 0.079 0.4915
Schistosoma mansoni memapsin-2 (A01 family) 0.0023 0.0093 0.0094
Loa Loa (eye worm) hypothetical protein 0.0018 0.0036 0.0041
Mycobacterium ulcerans cytochrome P450 191A3 Cyp191A3 0.0022 0.0083 0.0048
Mycobacterium ulcerans long-chain-fatty-acid-CoA ligase 0.0029 0.0165 0.0129
Schistosoma mansoni Pro-neuregulin-4 membrane-bound isoform (Pro-NRG4) [Contains: Neuregulin-4 (NRG-4)] 0.0017 0.0027 0.0027
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0037 0.0263 0.0267
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0158 0.1718 0.1746
Echinococcus multilocularis programmed cell death protein 0.0018 0.004 0.0041
Schistosoma mansoni hypothetical protein 0.0019 0.0049 0.005
Schistosoma mansoni notch 0.0017 0.0027 0.0027
Entamoeba histolytica Ran family GTPase 0.0021 0.0075 0.0227
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0145 0.1565 0.4725
Loa Loa (eye worm) cytochrome P450 family protein 0.004 0.0303 0.0353
Toxoplasma gondii proteasome subunit beta type, putative 0.0077 0.0744 0.1587
Brugia malayi calpain family protein 1 0.0331 0.3793 0.4408
Entamoeba histolytica cysteine protease, putative 0.0081 0.079 0.4915
Trypanosoma brucei calmodulin, putative 0.0019 0.0043 0.0006
Schistosoma mansoni cathepsin F (C01 family) 0.0145 0.1565 0.1591
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0037 0.0261 0.0684
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0145 0.1565 0.3384
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0073 0.0697 0.081
Brugia malayi Cathepsin L-like precursor 0.0145 0.1565 0.1819
Echinococcus multilocularis importin subunit beta 1 0.0029 0.0166 0.0169
Loa Loa (eye worm) hypothetical protein 0.0029 0.0165 0.0191
Onchocerca volvulus 0.0017 0.0027 0.0059
Trypanosoma brucei isocitrate dehydrogenase, putative 0.0019 0.005 0.0021
Mycobacterium tuberculosis Probable cytochrome P450 144 Cyp144 0.0022 0.0083 0.0035
Plasmodium vivax dipeptidyl aminopeptidase 3, putative 0.0037 0.0261 0.1117
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0037 0.0271 0.0512
Echinococcus multilocularis mitogen activated protein kinase 3 0.0049 0.0415 0.0422
Plasmodium vivax unspecified product 0.0037 0.0261 0.1117
Schistosoma mansoni cellular tumor antigen P53 0.0101 0.1033 0.105
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0019 0.0049 0.005
Schistosoma mansoni notch 0.0017 0.0027 0.0027
Loa Loa (eye worm) transcription factor SMAD2 0.049 0.5715 0.6641
Plasmodium falciparum serine repeat antigen 3 0.0037 0.0261 0.1117
Loa Loa (eye worm) hypothetical protein 0.0021 0.0078 0.009
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0037 0.0263 0.0267
Loa Loa (eye worm) programmed cell death protein 6 0.0019 0.0043 0.005
Trypanosoma cruzi cytoskeleton-associated protein CAP5.5, putative 0.0037 0.0271 0.0468
Trichomonas vaginalis taga, putative 0.0044 0.0344 0.094
Entamoeba histolytica cysteine protease, putative 0.0081 0.079 0.4915
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0037 0.0261 0.0266
Trichomonas vaginalis Clan CA, family C1, cathepsin F-like cysteine peptidase 0.0037 0.0261 0.0684
Entamoeba histolytica calpain large subunit domain III containing protein 0.0087 0.0869 0.5431
Echinococcus multilocularis cathepsin L cysteine protease 0.0145 0.1565 0.1591
Echinococcus multilocularis programmed cell death protein 0.0018 0.004 0.0041
Leishmania major importin beta-1 subunit, putative 0.0023 0.0101 0.0134
Onchocerca volvulus Neurogenic locus notch protein homolog 0.0017 0.0027 0.0059
Echinococcus granulosus protein jagged 1 0.0017 0.0027 0.0027
Plasmodium vivax serine-repeat antigen 3 (SERA) 0.0037 0.0261 0.1117
Leishmania major GTP-binding protein, putative 0.0021 0.0075 0.0077
Loa Loa (eye worm) hypothetical protein 0.0145 0.1565 0.1819
Trypanosoma brucei hypothetical protein, conserved 0.0073 0.0697 0.1457
Echinococcus multilocularis ATP binding cassette subfamily B (MDR:TAP) 0.0044 0.0344 0.035
Brugia malayi aspartic protease BmAsp-1, identical 0.0023 0.0093 0.0108
Loa Loa (eye worm) hypothetical protein 0.0018 0.0043 0.005
Loa Loa (eye worm) hypothetical protein 0.005 0.0417 0.0484
Echinococcus multilocularis multidrug resistance protein 1 0.0044 0.0344 0.035
Schistosoma mansoni multidrug resistance protein 0.0044 0.0344 0.035
Entamoeba histolytica prolyl oligopeptidase family protein 0.0041 0.0316 0.1808
Echinococcus multilocularis calbindin 32 0.0019 0.0043 0.0044
Schistosoma mansoni subfamily C1A unassigned peptidase (C01 family) 0.0037 0.0261 0.0266
Mycobacterium ulcerans cytochrome P450 124A1, Cyp124A1 0.0022 0.0083 0.0048
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0023 0.0093 0.0094
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0037 0.0261 0.0684
Onchocerca volvulus 0.0018 0.0036 0.0079
Echinococcus multilocularis Ataxin 2, N terminal,domain containing protein 0.0022 0.0088 0.0089
Trypanosoma cruzi cytoskeleton-associated protein CAP5.5, putative 0.0037 0.0271 0.0468
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0145 0.1565 0.3384
Loa Loa (eye worm) hypothetical protein 0.0017 0.0027 0.0031
Leishmania major cathepsin L-like protease 0.0145 0.1565 0.3384
Loa Loa (eye worm) hypothetical protein 0.0044 0.0344 0.04
Echinococcus multilocularis neurogenic locus notch protein 0.0017 0.0027 0.0027
Loa Loa (eye worm) calpain family protein 1 0.0331 0.3793 0.4408
Plasmodium falciparum cysteine proteinase falcipain 3 0.0145 0.1565 0.7717
Schistosoma mansoni cercarial elastase (S01 family) 0.0018 0.0036 0.0036
Onchocerca volvulus Peroxidase homolog 0.0173 0.1897 0.4173
Schistosoma mansoni calcium binding atopy-related autoantigen 0.0019 0.0043 0.0044
Leishmania major cysteine peptidase C (CPC),CPC cysteine peptidase, Clan CA, family C1, Cathepsin B-like 0.0158 0.1718 0.3723
Schistosoma mansoni hypothetical protein 0.0018 0.004 0.0041
Brugia malayi EGF-like domain containing protein 0.0017 0.0027 0.0031
Onchocerca volvulus 0.0018 0.0036 0.0079
Trichomonas vaginalis importin beta-1, putative 0.0023 0.0101 0.0187
Plasmodium falciparum cysteine proteinase falcipain 2b 0.0145 0.1565 0.7717
Trypanosoma cruzi cysteine peptidase (N-terminal), putative 0.0081 0.079 0.152
Echinococcus granulosus notch 0.0017 0.0027 0.0027
Schistosoma mansoni cathepsin s 0.0044 0.0349 0.0355
Echinococcus multilocularis calcium uptake protein 1 0.0019 0.0043 0.0044
Echinococcus multilocularis calumenin 0.0019 0.0043 0.0044
Giardia lamblia Cathepsin B precursor 0.0037 0.0261 0.1387
Toxoplasma gondii aspartyl proteinase (eimepsin), putative 0.0023 0.0093 0.0146
Mycobacterium tuberculosis Probable transmembrane multidrug efflux pump 0.0044 0.0344 0.0297
Echinococcus granulosus prolyl endopeptidase 0.0393 0.4546 0.4621
Brugia malayi MH1 domain containing protein 0.0033 0.0222 0.0258
Plasmodium vivax GTP-binding nuclear protein RAN/TC4, putative 0.0021 0.0075 0.0175
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0037 0.0271 0.0468
Trichomonas vaginalis ATP-binding cassette transporter, putative 0.003 0.0186 0.045
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0125 0.1319 0.2593
Loa Loa (eye worm) prolyl oligopeptidase 0.0041 0.0316 0.0367
Echinococcus granulosus mothers against decapentaplegic 5 0.0033 0.0222 0.0226
Plasmodium vivax AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0019 0.0048 0.004
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.009 0.0899 0.1045
Entamoeba histolytica P-glycoprotein-2, putative 0.0044 0.0344 0.1989
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0101 0.1037 0.3087
Mycobacterium leprae conserved hypothetical protein 0.0073 0.0697 0.0619
Onchocerca volvulus 0.0017 0.0027 0.0059
Onchocerca volvulus 0.0035 0.0237 0.0522
Echinococcus multilocularis mothers against decapentaplegic 5 0.0033 0.0222 0.0226
Loa Loa (eye worm) hypothetical protein 0.0017 0.0027 0.0031
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0037 0.0261 0.0304
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0037 0.0271 0.0468
Trichomonas vaginalis set domain proteins, putative 0.0287 0.3268 1
Brugia malayi hypothetical protein 0.0032 0.0205 0.0239
Schistosoma mansoni septate junction protein 0.0017 0.0027 0.0027
Leishmania major cathepsin L-like protease 0.0145 0.1565 0.3384
Onchocerca volvulus Chorion peroxidase homolog 0.0173 0.1897 0.4173
Leishmania major prolyl oligopeptidase, putative,serine peptidase clan SC, family S9A, putative 0.0393 0.4546 1
Schistosoma mansoni aminopeptidase PILS (M01 family) 0.0018 0.0036 0.0036
Loa Loa (eye worm) D-ets-4 DNA binding domain-containing protein 0.0075 0.0723 0.084
Brugia malayi AMP-binding enzyme family protein 0.0029 0.0165 0.0191
Trichomonas vaginalis esterase, putative 0.0073 0.0697 0.2034
Trypanosoma cruzi major cysteine proteinase, putative 0.0037 0.0261 0.0448
Loa Loa (eye worm) hypothetical protein 0.0029 0.0165 0.0191
Brugia malayi Animal haem peroxidase family protein 0.0173 0.1897 0.2205
Loa Loa (eye worm) calpain D 0.0037 0.0271 0.0315
Loa Loa (eye worm) hypothetical protein 0.0017 0.0027 0.0031
Mycobacterium tuberculosis Probable peptidase 0.0156 0.17 0.1659
Schistosoma mansoni notch 0.0017 0.0027 0.0027
Echinococcus multilocularis GPCR, family 2 0.0019 0.0049 0.005
Brugia malayi MAP kinase sur-1 0.0049 0.0415 0.0482
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0037 0.0271 0.0512
Mycobacterium tuberculosis Probable cytochrome P450 140 Cyp140 0.0022 0.0083 0.0035
Loa Loa (eye worm) hypothetical protein 0.0017 0.0027 0.0031
Trypanosoma brucei cytoskeleton-associated protein CAP5.5, putative 0.0037 0.0271 0.0512
Echinococcus multilocularis protein jagged 2 0.0017 0.0027 0.0027
Loa Loa (eye worm) hypothetical protein 0.0173 0.1897 0.2205
Trichomonas vaginalis D-aminoacylase, putative 0.0073 0.0697 0.2034
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0037 0.0261 0.0684
Schistosoma mansoni smdr2 0.0044 0.0344 0.035
Trichomonas vaginalis ATP-binding cassette transporter, putative 0.0044 0.0344 0.094
Entamoeba histolytica P-glyco protein 6, putative 0.0044 0.0344 0.1989
Loa Loa (eye worm) MH1 domain-containing protein 0.0033 0.0222 0.0258
Loa Loa (eye worm) hypothetical protein 0.0073 0.0697 0.081
Mycobacterium leprae PROBABLE PROTEASE II PTRBB (OLIGOPEPTIDASE B) 0.0156 0.17 0.163
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0158 0.1718 0.5197
Brugia malayi EGF-like domain containing protein 0.0017 0.0027 0.0031
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0018 0.0036 0.0036
Plasmodium vivax importin-beta 2, putative 0.0029 0.0166 0.0637
Brugia malayi isocitrate dehydrogenase 0.0019 0.005 0.0058
Brugia malayi programmed cell death protein 6 0.0018 0.004 0.0047
Schistosoma mansoni hypothetical protein 0.0018 0.0036 0.0036
Mycobacterium tuberculosis Possible cytochrome P450 135B1 Cyp135B1 0.0022 0.0083 0.0035
Echinococcus granulosus mitogen activated protein kinase 0.0049 0.0415 0.0422
Toxoplasma gondii isocitrate dehydrogenase 0.0019 0.005 0.0051
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.0021 0.0075 0.007
Giardia lamblia Cathepsin B precursor 0.0037 0.0261 0.1387
Trichomonas vaginalis ABC transporter, putative 0.0044 0.0344 0.094
Giardia lamblia Hypothetical protein 0.0037 0.0261 0.1387
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0049 0.0415 0.0759
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0037 0.0271 0.0468
Echinococcus multilocularis Dipeptidyl peptidase 9 0.0041 0.0316 0.0321
Toxoplasma gondii exonuclease III APE 0.0019 0.0048 0.0048
Plasmodium falciparum plasmepsin I 0.0023 0.0093 0.0265
Plasmodium vivax calcium-dependent protein kinase 3, putative 0.0019 0.0046 0.0027
Loa Loa (eye worm) cytochrome P450 family protein 0.004 0.0303 0.0353
Plasmodium falciparum multidrug resistance protein 1 0.0044 0.0344 0.1535
Onchocerca volvulus Prolyl endopeptidase homolog 0.0393 0.4546 1
Echinococcus granulosus importin subunit beta 1 0.0029 0.0166 0.0169
Trypanosoma cruzi kinesin, putative 0.0087 0.0869 0.1679
Giardia lamblia Cysteine protease 0.0037 0.0261 0.1387
Echinococcus granulosus GA binding protein alpha chain 0.0075 0.0723 0.0735
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0145 0.1565 0.4725
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0125 0.1319 0.2593
Trichomonas vaginalis Clan CA, family C2, calpain-like cysteine peptidase 0.0037 0.0271 0.0714
Giardia lamblia Cathepsin B precursor 0.0037 0.0261 0.1387
Trichomonas vaginalis calpain, putative 0.0037 0.0271 0.0714
Schistosoma mansoni cathepsin F (C01 family) 0.0145 0.1565 0.1591
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0037 0.0271 0.0512
Brugia malayi hypothetical protein 0.0023 0.0093 0.0108
Schistosoma mansoni NADP-specific isocitrate dehydrogenase 0.0019 0.005 0.0051
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0145 0.1565 0.4725
Entamoeba histolytica cysteine protease, putative 0.0037 0.0261 0.1448
Mycobacterium ulcerans cytochrome P450 187A4 Cyp187A4 0.0022 0.0083 0.0048
Echinococcus multilocularis cathepsin L 0.0037 0.0261 0.0266
Mycobacterium ulcerans cytochrome P450 143A4 Cyp143A4 0.0022 0.0083 0.0048
Brugia malayi Cathepsin L-like precursor 0.0145 0.1565 0.1819
Entamoeba histolytica dipeptidyl-peptidase, putative 0.0041 0.0316 0.1808
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0145 0.1565 0.3384
Mycobacterium ulcerans cytochrome P450 142A3 Cyp142A3 0.0022 0.0083 0.0048
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.0019 0.0048 0.0049
Loa Loa (eye worm) hypothetical protein 0.0017 0.0027 0.0031
Entamoeba histolytica proteasome subunit beta type 5 precursor, putative 0.0077 0.0744 0.4613
Trichomonas vaginalis lipid A export ATP-binding/permease protein msba, putative 0.0044 0.0344 0.094
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0019 0.005 0.0051
Loa Loa (eye worm) hypothetical protein 0.0029 0.0165 0.0191
Loa Loa (eye worm) hypothetical protein 0.0018 0.004 0.0047
Entamoeba histolytica dipeptidyl-peptidase, putative 0.0041 0.0316 0.1808
Schistosoma mansoni slit 0.0017 0.0027 0.0027
Plasmodium vivax aspartyl protease, putative 0.0183 0.2016 1
Mycobacterium tuberculosis Conserved protein 0.011 0.1143 0.11
Echinococcus granulosus GPCR family 2 0.0019 0.0049 0.005
Leishmania major calpain-like protein, putative,cysteine peptidase, Clan CA, family C2, putative 0.0037 0.0271 0.0512
Trypanosoma brucei prolyl oligopeptidase, putative 0.0156 0.17 0.3683
Entamoeba histolytica protein kinase, putative 0.0088 0.0874 0.5466
Loa Loa (eye worm) hypothetical protein 0.0041 0.0316 0.0367
Entamoeba histolytica cysteine proteinase 1, putative 0.0081 0.079 0.4915
Loa Loa (eye worm) trypsin family protein 0.0018 0.0036 0.0041
Echinococcus granulosus acylamino acid releasing enzyme 0.0041 0.0316 0.0321
Trypanosoma cruzi cysteine proteinase, putative 0.0081 0.079 0.152
Trypanosoma cruzi prolyl endopeptidase 0.0393 0.4546 0.9138
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.009 0.0899 0.1045
Loa Loa (eye worm) latrophilin receptor protein 2 0.0019 0.0049 0.0057
Echinococcus granulosus snurportin 1 0.0307 0.3513 0.3571
Echinococcus multilocularis GTP binding nuclear protein Ran 0.0021 0.0075 0.0076
Loa Loa (eye worm) notch protein 0.0017 0.0027 0.0031
Schistosoma mansoni cpg binding protein 0.0037 0.0261 0.0265
Schistosoma mansoni cercarial elastase (S01 family) 0.0018 0.0036 0.0036
Brugia malayi exodeoxyribonuclease III family protein 0.0019 0.0048 0.0056
Schistosoma mansoni ran 0.0021 0.0075 0.0076
Trichomonas vaginalis Clan CA, family C1, cathepsin L or H-like cysteine peptidase 0.0037 0.0261 0.0684
Echinococcus granulosus ATP binding cassette subfamily B MDR:TAP 0.0044 0.0344 0.035
Echinococcus granulosus ATP binding cassette subfamily B MDR:TAP 0.0044 0.0344 0.035
Schistosoma mansoni TGF-beta signal transducer Smad2 0.0033 0.0222 0.0226
Loa Loa (eye worm) hypothetical protein 0.0037 0.0261 0.0304
Schistosoma mansoni cercarial elastase (S01 family) 0.0018 0.0036 0.0036
Giardia lamblia Hypothetical protein 0.0037 0.0261 0.1387
Brugia malayi Pepsin A precursor 0.0023 0.0093 0.0108
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative 0.0019 0.0048 0.0017
Mycobacterium ulcerans cytochrome P450 123A3 Cyp123A3 0.0022 0.0083 0.0048
Entamoeba histolytica cysteine proteinase, putative 0.0081 0.079 0.4915
Brugia malayi gamma-secretase subunit aph-1 0.0731 0.8606 1
Trichomonas vaginalis abcb9, putative 0.0044 0.0344 0.094
Trypanosoma cruzi isocitrate dehydrogenase, putative 0.0019 0.005 0.0019
Echinococcus granulosus subfamily S1A unassigned peptidase S01 family 0.0018 0.0036 0.0036
Trichomonas vaginalis penicillin-binding protein, putative 0.0073 0.0697 0.2034
Loa Loa (eye worm) hypothetical protein 0.0037 0.0261 0.0304
Giardia lamblia Cathepsin B precursor 0.0158 0.1718 1
Brugia malayi GTP-binding nuclear protein RAN/TC4 0.0021 0.0075 0.0087
Loa Loa (eye worm) hypothetical protein 0.0101 0.1037 0.1205
Giardia lamblia Cathepsin L precursor 0.0037 0.0261 0.1387
Plasmodium vivax plasmepsin V, putative 0.0023 0.0093 0.0265
Brugia malayi calcium-binding protein 0.0018 0.004 0.0047
Echinococcus granulosus microtubule associated protein 2 0.0833 0.9838 1
Mycobacterium ulcerans cytochrome P450 189A7 Cyp189A7 0.0022 0.0083 0.0048
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0145 0.1565 0.4725
Brugia malayi Animal haem peroxidase family protein 0.0173 0.1897 0.2205
Echinococcus granulosus Smad4 0.0033 0.0222 0.0226
Echinococcus granulosus neural cadherin 0.0017 0.0027 0.0027
Trichomonas vaginalis Family T1, proteasome beta subunit, threonine peptidase 0.0077 0.0744 0.2179
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0081 0.079 0.2322
Mycobacterium tuberculosis Conserved protein 0.0073 0.0697 0.0652
Echinococcus multilocularis neural cadherin 0.0017 0.0027 0.0027
Leishmania major lanosterol 14-alpha-demethylase, putative 0.0022 0.0083 0.0095
Mycobacterium ulcerans cytochrome p450 150 cyp150 0.0022 0.0083 0.0048
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0037 0.0271 0.0468
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.009 0.0899 0.0914
Echinococcus multilocularis acylamino acid releasing enzyme 0.0041 0.0316 0.0321
Echinococcus multilocularis neurogenic locus protein delta 0.0017 0.0027 0.0027
Loa Loa (eye worm) cytochrome P450 family protein 0.0081 0.0792 0.092
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0252 0.2851 0.3312
Echinococcus granulosus gamma secretase subunit aph 1 0.0731 0.8606 0.8749
Trichomonas vaginalis multidrug resistance protein 1, 2, putative 0.0044 0.0344 0.094
Loa Loa (eye worm) hypothetical protein 0.0101 0.1037 0.1205
Brugia malayi Cathepsin L-like precursor 0.0101 0.1037 0.1205
Echinococcus multilocularis fat cadherin tumor suppressor 0.0017 0.0027 0.0027
Brugia malayi beta-lactamase family protein 0.0073 0.0697 0.081
Loa Loa (eye worm) hypothetical protein 0.0243 0.2745 0.319
Brugia malayi Animal haem peroxidase family protein 0.0173 0.1897 0.2205
Schistosoma mansoni reticulocalbin 0.0018 0.004 0.0041
Brugia malayi calpain 5 0.0037 0.0271 0.0315
Echinococcus multilocularis EF HAND 1, calcium binding site 0.0018 0.004 0.0041
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.009 0.0899 0.0914
Giardia lamblia Alanyl dipeptidyl peptidase 0.0041 0.0316 0.1711
Brugia malayi EGF-like domain containing protein 0.0017 0.0027 0.0031
Leishmania major cytochrome p450-like protein 0.004 0.0303 0.0584
Onchocerca volvulus 0.0029 0.0165 0.0362
Giardia lamblia Dipeptidyl-peptidase I precursor 0.0037 0.0261 0.1387
Brugia malayi Blistered cuticle protein 3 0.0173 0.1897 0.2205
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0125 0.1319 0.2593
Echinococcus multilocularis TGF beta signal transducer SmadC 0.0033 0.0222 0.0226
Plasmodium vivax aspartyl protease, putative 0.0183 0.2016 1
Mycobacterium ulcerans cytochrome P450 126A3 Cyp126A3 0.0022 0.0083 0.0048
Echinococcus multilocularis peroxidasin 0.0173 0.1897 0.1929
Leishmania major p-glycoprotein 0.0044 0.0344 0.0673
Toxoplasma gondii EFHC1, putative 0.0018 0.004 0.0031
Entamoeba histolytica papain family cysteine protease domain containing protein 0.0037 0.0261 0.1448
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0125 0.1319 0.2838
Mycobacterium tuberculosis Probable chain -fatty-acid-CoA ligase FadD13 (fatty-acyl-CoA synthetase) 0.0029 0.0165 0.0117
Brugia malayi Papain family cysteine protease containing protein 0.0037 0.0261 0.0304
Toxoplasma gondii prolyl endopeptidase 0.0393 0.4546 1
Schistosoma mansoni microtubule-associated protein tau 0.0833 0.9838 1
Echinococcus multilocularis EF hand domain containing family member A2 0.0018 0.004 0.0041
Brugia malayi notch-like transmembrane receptor 0.0017 0.0027 0.0031
Plasmodium vivax isocitrate dehydrogenase [NADP], mitochondrial, putative 0.0019 0.005 0.0047
Onchocerca volvulus 0.0173 0.1897 0.4173
Brugia malayi MH1 domain containing protein 0.0033 0.0222 0.0258
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0037 0.0271 0.0468
Plasmodium vivax aspartyl proteinase, putative 0.0023 0.0093 0.0265
Loa Loa (eye worm) pigment dispersing factor receptor c 0.006 0.0544 0.0632
Echinococcus multilocularis enteropeptidase 0.0018 0.0036 0.0036
Trichomonas vaginalis ran, putative 0.0021 0.0075 0.0107
Trypanosoma cruzi apurinic/apyrimidinic endonuclease 0.0019 0.0048 0.0016
Trypanosoma cruzi Lanosterol 14-alpha demethylase 0.0022 0.0083 0.0087
Brugia malayi Cathepsin L-like precursor 0.0145 0.1565 0.1819
Schistosoma mansoni hypothetical protein 0.0022 0.0083 0.0085
Schistosoma mansoni family C2 unassigned peptidase (C02 family) 0.0349 0.4013 0.408
Loa Loa (eye worm) hypothetical protein 0.0017 0.0027 0.0031
Echinococcus multilocularis fibropellin Ia 0.0017 0.0027 0.0027
Loa Loa (eye worm) CYP4Cod1 0.004 0.0303 0.0353
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0023 0.0093 0.0094
Echinococcus granulosus ATP binding cassette subfamily B MDR:TAP 0.0044 0.0344 0.035
Trypanosoma cruzi cruzipain precursor, putative 0.0145 0.1565 0.3093
Loa Loa (eye worm) hypothetical protein 0.0064 0.0592 0.0688
Echinococcus granulosus histone lysine methyltransferase setb 0.0037 0.0263 0.0267
Echinococcus multilocularis protein jagged 1 0.0017 0.0027 0.0027
Echinococcus multilocularis Mastin 0.0018 0.0036 0.0036
Trypanosoma cruzi hypothetical protein, conserved 0.0073 0.0697 0.1331
Trypanosoma brucei calpain, putative 0.0037 0.0271 0.0512
Trypanosoma brucei Dipeptidyl-peptidase 8-like, putative 0.0041 0.0316 0.0612
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0037 0.0261 0.0684
Mycobacterium tuberculosis Conserved hypothetical protein 0.011 0.1143 0.11
Trypanosoma cruzi cysteine peptidase, putative 0.0145 0.1565 0.3093
Plasmodium falciparum plasmepsin X 0.0183 0.2016 1
Echinococcus multilocularis calpain family protein 1, d 0.0243 0.2745 0.2791
Entamoeba histolytica hypothetical protein 0.0023 0.0101 0.0397
Trypanosoma cruzi calpain cysteine peptidase, putative 0.0037 0.0271 0.0468
Entamoeba histolytica cysteine protease, putative 0.0081 0.079 0.4915
Trichomonas vaginalis abcb9, putative 0.0044 0.0344 0.094
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0044 0.0349 0.0406
Echinococcus granulosus neurogenic locus notch protein 4 0.0017 0.0027 0.0027
Plasmodium vivax unspecified product 0.0044 0.0349 0.1562
Entamoeba histolytica cysteine proteinase, putative 0.0081 0.079 0.4915
Brugia malayi Pre-SET motif family protein 0.0252 0.2851 0.3312
Plasmodium vivax vivapain-1 0.0081 0.079 0.3793
Mycobacterium ulcerans acyl-CoA synthetase 0.0029 0.0165 0.0129
Chlamydia trachomatis ABC transporter ATP binding protein/permease 0.0044 0.0344 1
Leishmania major protein kinase, putative 0.0019 0.0046 0.0012
Loa Loa (eye worm) hypothetical protein 0.0101 0.1037 0.1205
Entamoeba histolytica hypothetical protein, conserved 0.0041 0.0316 0.1808
Schistosoma mansoni gabp alpha 0.0075 0.0723 0.0735
Schistosoma mansoni cathepsin C 0.0037 0.0261 0.0266
Plasmodium vivax multidrug resistance protein 1, putative 0.0044 0.0344 0.1535
Loa Loa (eye worm) calpain 5 0.0087 0.0869 0.1009
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0428 0.4971 0.5053
Schistosoma mansoni hypothetical protein 0.0017 0.0027 0.0027
Echinococcus multilocularis Peptidase S1 S6, chymotrypsin Hap 0.0018 0.0036 0.0036
Brugia malayi cathepsin L-like cysteine proteinase 0.0037 0.0261 0.0304
Echinococcus multilocularis multidrug resistance protein 1 0.0044 0.0344 0.035
Onchocerca volvulus Cathepsin L homolog 0.0037 0.0261 0.0575
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0021 0.0078 0.0042
Plasmodium vivax plasmepsin IV, putative 0.0023 0.0093 0.0265
Trichomonas vaginalis multidrug resistance protein 1, 2, putative 0.0044 0.0344 0.094
Schistosoma mansoni centrin-related 0.0018 0.004 0.0041
Plasmodium falciparum plasmepsin VIII, putative 0.0023 0.0093 0.0265
Schistosoma mansoni calmodulin 0.0018 0.004 0.0041
Brugia malayi Calcitonin receptor-like protein seb-1 0.006 0.0544 0.0632
Brugia malayi Trypsin family protein 0.0018 0.0036 0.0041
Loa Loa (eye worm) hypothetical protein 0.0037 0.0261 0.0304
Entamoeba histolytica cysteine protease, putative 0.0081 0.079 0.4915
Trypanosoma cruzi proteasome subunit beta type-5, putative 0.0077 0.0744 0.1426
Plasmodium falciparum dipeptidyl aminopeptidase 3 0.0037 0.0261 0.1117
Toxoplasma gondii histone lysine methyltransferase SET1 0.0067 0.0626 0.1327
Loa Loa (eye worm) multidrug resistance protein 3 0.0044 0.0344 0.04
Trichomonas vaginalis D-aminoacylase, putative 0.0073 0.0697 0.2034
Mycobacterium ulcerans hypothetical protein 0.011 0.1143 0.1112
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0049 0.0415 0.0759
Trypanosoma brucei prolyl endopeptidase 0.0393 0.4546 1
Trichomonas vaginalis lipid A export ATP-binding/permease protein msba, putative 0.0044 0.0344 0.094
Brugia malayi Latrophilin receptor protein 2 0.0019 0.0049 0.0057
Brugia malayi Cytochrome P450 family protein 0.0022 0.0083 0.0097
Leishmania major mitogen activated protein kinase 4, putative;with=GeneDB:LmxM19.1440 0.0049 0.0415 0.0831
Echinococcus multilocularis hypothetical protein 0.0125 0.1319 0.1341
Brugia malayi EGF-like domain containing protein 0.0017 0.0027 0.0031
Schistosoma mansoni hypothetical protein 0.0037 0.0271 0.0275
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0145 0.1565 0.4725
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0125 0.1319 0.2593
Brugia malayi Trypsin family protein 0.0018 0.0036 0.0041
Entamoeba histolytica cysteine protease, putative 0.0037 0.0261 0.1448
Echinococcus granulosus centrin 2 0.0018 0.004 0.0041
Trichomonas vaginalis lipid A export ATP-binding/permease protein msba, putative 0.0044 0.0344 0.094
Leishmania major mitogen activated protein kinase, putative,map kinase, putative 0.0049 0.0415 0.0831
Brugia malayi aspartic protease BmAsp-2, identical 0.0023 0.0093 0.0108
Loa Loa (eye worm) aspartyl protease 6 0.0023 0.0093 0.0108
Brugia malayi Muscle positioning protein 4 0.0017 0.0027 0.0031
Onchocerca volvulus Dipeptidyl peptidase family member 1 homolog 0.0041 0.0316 0.0695
Echinococcus granulosus protein jagged 2 0.0017 0.0027 0.0027
Brugia malayi fibroinase precursor 0.0037 0.0261 0.0304
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0037 0.0271 0.0512
Trypanosoma cruzi cysteine protease, putative 0.0081 0.079 0.152
Echinococcus granulosus calcium uptake protein 1 0.0019 0.0043 0.0044
Brugia malayi Pre-SET motif family protein 0.0037 0.0263 0.0305
Plasmodium vivax hypothetical protein, conserved 0.0073 0.0697 0.3322
Schistosoma mansoni calpain-2 (C02 family) 0.0037 0.0271 0.0275
Loa Loa (eye worm) hypothetical protein 0.0173 0.1897 0.2205
Toxoplasma gondii CMGC kinase, MAPK family (ERK) MAPK-1 0.0049 0.0415 0.0859
Echinococcus multilocularis 0.0022 0.0083 0.0085
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0037 0.0271 0.0512
Loa Loa (eye worm) hypothetical protein 0.0017 0.0027 0.0031
Mycobacterium tuberculosis Probable cytochrome P450 143 Cyp143 0.0022 0.0083 0.0035
Schistosoma mansoni cercarial elastase (S01 family) 0.0018 0.0036 0.0036
Trichomonas vaginalis CMGC family protein kinase 0.0049 0.0415 0.116
Loa Loa (eye worm) prolyl oligopeptidase 0.0041 0.0316 0.0367
Onchocerca volvulus 0.0018 0.0036 0.0079
Echinococcus granulosus protein jagged 2 0.0017 0.0027 0.0027
Leishmania major cathepsin L-like protease 0.0145 0.1565 0.3384
Echinococcus multilocularis gamma secretase subunit aph 1 0.0731 0.8606 0.8749
Schistosoma mansoni subfamily C1A unassigned peptidase (C01 family) 0.0037 0.0261 0.0266
Loa Loa (eye worm) hypothetical protein 0.0073 0.0697 0.081
Plasmodium vivax aspartyl protease, putative 0.0023 0.0093 0.0265
Trichomonas vaginalis hypothetical protein 0.0037 0.0271 0.0714
Mycobacterium tuberculosis Conserved protein 0.0073 0.0697 0.0652
Mycobacterium tuberculosis Conserved protein 0.0073 0.0697 0.0652
Onchocerca volvulus 0.0073 0.0697 0.1533
Onchocerca volvulus Dual oxidase homolog 0.0173 0.1897 0.4173
Mycobacterium tuberculosis Probable cytochrome P450 136 Cyp136 0.0022 0.0083 0.0035
Trichomonas vaginalis CMGC family protein kinase 0.0049 0.0415 0.116
Mycobacterium tuberculosis Proteasome alpha subunit PrcA; assembles with beta subunit PrcB. 0.0847 1 1
Trypanosoma brucei calpain-like protein, putative 0.0125 0.1319 0.2838
Onchocerca volvulus 0.0019 0.0043 0.0095
Mycobacterium tuberculosis Probable cytochrome P450 137 Cyp137 0.0022 0.0083 0.0035
Schistosoma mansoni cercarial elastase (S01 family) 0.0018 0.0036 0.0036
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0018 0.0036 0.0036
Schistosoma mansoni cercarial elastase (S01 family) 0.0018 0.0036 0.0036
Plasmodium falciparum importin beta, putative 0.0029 0.0166 0.0637
Toxoplasma gondii cathepsin CPC2 0.0037 0.0261 0.0519
Echinococcus multilocularis cpg binding protein 0.0037 0.0261 0.0265
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.0145 0.1565 0.4725
Schistosoma mansoni gamma-secretase subunit aph-1 0.0731 0.8606 0.8749
Schistosoma mansoni hypothetical protein 0.0018 0.0036 0.0036
Mycobacterium tuberculosis Probable cytochrome P450 125 Cyp125 0.0022 0.0083 0.0035
Echinococcus multilocularis proteasome (prosome, macropain) 0.0077 0.0744 0.0756
Leishmania major cytochrome p450-like protein 0.0022 0.0083 0.0095
Schistosoma mansoni prolyl oligopeptidase (S09 family) 0.0393 0.4546 0.4621
Mycobacterium leprae Probable lipase LipE 0.0073 0.0697 0.0619
Echinococcus granulosus NADP dependent isocitrate dehydrogenase 0.0019 0.005 0.0051
Schistosoma mansoni hypothetical protein 0.0494 0.5758 0.5853
Plasmodium vivax ataxin-2 like protein, putative 0.005 0.0417 0.1905
Plasmodium vivax vivapain-2 0.0145 0.1565 0.7717
Loa Loa (eye worm) hypothetical protein 0.0173 0.1897 0.2205
Brugia malayi Cathepsin L-like precursor 0.0145 0.1565 0.1819
Echinococcus granulosus cathepsin L 0.0081 0.079 0.0803
Echinococcus multilocularis slit 2 protein 0.0017 0.0027 0.0027
Echinococcus multilocularis calpain 7 (C02 family) 0.0125 0.1319 0.1341
Loa Loa (eye worm) hypothetical protein 0.0018 0.004 0.0047
Trypanosoma cruzi CAMK/CAMKL family protein kinase, putative 0.0019 0.0046 0.0011
Mycobacterium tuberculosis Probable hydrolase 0.0073 0.0697 0.0652
Plasmodium falciparum plasmepsin V 0.0023 0.0093 0.0265
Echinococcus granulosus neuronal calcium sensor 0.0018 0.004 0.0041
Schistosoma mansoni cpg binding protein 0.0035 0.0237 0.0241
Entamoeba histolytica cysteine protease, putative 0.0037 0.0261 0.1448
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.0019 0.0048 0.0016
Leishmania major hypothetical protein, unknown function 0.0037 0.0271 0.0512
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0018 0.0036 0.0036
Plasmodium falciparum ataxin-2 like protein, putative 0.005 0.0417 0.1905
Brugia malayi EF hand family protein 0.0018 0.004 0.0047
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.006 0.0544 0.0632
Echinococcus multilocularis smad 0.0033 0.0222 0.0226
Trypanosoma brucei cysteine peptidase, putative 0.0037 0.0271 0.0512
Echinococcus multilocularis isocitrate dehydrogenase 0.0019 0.005 0.0051
Entamoeba histolytica grainin, putative 0.0019 0.0043 0.0019
Mycobacterium ulcerans exodeoxyribonuclease III protein XthA 0.0019 0.0048 0.0013
Entamoeba histolytica cysteine proteinase, putative 0.0101 0.1037 0.6533
Mycobacterium tuberculosis Probable cytochrome P450 132 Cyp132 0.0022 0.0083 0.0035
Mycobacterium ulcerans cytochrome P450 144A4 Cyp144A4 0.0022 0.0083 0.0048
Echinococcus multilocularis neurogenic locus notch protein 4 0.0017 0.0027 0.0027
Echinococcus granulosus cathepsin d lysosomal aspartyl protease 0.0023 0.0093 0.0094
Brugia malayi Fli-1 protein 0.0228 0.256 0.2975
Onchocerca volvulus 0.0037 0.0261 0.0575
Giardia lamblia Cathepsin L-like protease 0.0037 0.0261 0.1387
Echinococcus granulosus cathepsin l cysteine peptidase 0.0145 0.1565 0.1591
Trypanosoma cruzi cysteine peptidase, putative 0.0081 0.079 0.152
Brugia malayi Cathepsin L-like cysteine proteinase 0.0101 0.1037 0.1205
Onchocerca volvulus 0.0145 0.1565 0.3443
Echinococcus multilocularis ATP binding cassette subfamily B (MDR:TAP) 0.0044 0.0344 0.035
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0023 0.0093 0.0094
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0145 0.1565 0.4725
Brugia malayi Cadherin domain containing protein 0.0017 0.0027 0.0031
Onchocerca volvulus 0.0037 0.0263 0.0578
Echinococcus multilocularis snurportin 1 0.0307 0.3513 0.3571
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.009 0.0899 0.0914
Loa Loa (eye worm) hypothetical protein 0.0018 0.0036 0.0041
Onchocerca volvulus 0.0145 0.1565 0.3443
Loa Loa (eye worm) hypothetical protein 0.0044 0.0349 0.0406
Schistosoma mansoni ets-related 0.0228 0.256 0.2602
Brugia malayi hypothetical protein 0.0018 0.0036 0.0041
Plasmodium vivax proteasome subunit beta type-5, putative 0.0077 0.0744 0.356
Trypanosoma cruzi major cysteine proteinase, putative 0.0037 0.0261 0.0448
Trypanosoma brucei CAMK/CAMKL family protein kinase, putative 0.0019 0.0046 0.0012
Trichomonas vaginalis Clan CA, family C1, cathepsin H-like cysteine peptidase 0.0037 0.0261 0.0684
Schistosoma mansoni hypothetical protein 0.0018 0.004 0.0041
Brugia malayi Transmembrane cell adhesion receptor mua-3 precursor, putative 0.0017 0.0027 0.0031
Brugia malayi Ets-domain containing protein 0.0075 0.0723 0.084
Trypanosoma brucei Alpha/beta hydrolase domain-containing protein 0.0041 0.0316 0.0612
Loa Loa (eye worm) hypothetical protein 0.0428 0.4971 0.5776
Plasmodium vivax serine-repeat antigen (SERA), putative 0.0037 0.0261 0.1117
Leishmania major cysteine peptidase A (CPA) 0.0145 0.1565 0.3384
Leishmania major oligopeptidase B-like protein,serine peptidase, clan SC, family S9A-like protein 0.0156 0.17 0.3683
Plasmodium vivax acyl-CoA synthetase, putative 0.0021 0.0078 0.0188
Trypanosoma brucei serine peptidase, Clan SC, Family S9B 0.0041 0.0316 0.0612
Mycobacterium ulcerans proteasome PrcA 0.0847 1 1
Trichomonas vaginalis calpain, putative 0.0037 0.0271 0.0714
Brugia malayi cathepsin F-like cysteine proteinase 0.0044 0.0349 0.0406
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0145 0.1565 0.4725
Loa Loa (eye worm) hypothetical protein 0.0041 0.0316 0.0367
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0145 0.1565 0.4725
Entamoeba histolytica cysteine protease, putative 0.0081 0.079 0.4915
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0145 0.1565 0.1819
Schistosoma mansoni hypothetical protein 0.0058 0.0521 0.0529
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0037 0.0271 0.0512
Brugia malayi hypothetical protein 0.0023 0.0093 0.0108
Echinococcus granulosus protein jagged 1 0.0017 0.0027 0.0027
Entamoeba histolytica acyl-coA synthetase, putative 0.0029 0.0165 0.0814
Loa Loa (eye worm) hypothetical protein 0.0018 0.0036 0.0041
Plasmodium vivax aspartyl proteinase, putative 0.0023 0.0093 0.0265
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0081 0.079 0.1663
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0073 0.0697 0.081
Brugia malayi calpain 5 0.0087 0.0869 0.1009
Loa Loa (eye worm) hypothetical protein 0.006 0.0544 0.0632
Onchocerca volvulus 0.0018 0.0036 0.0079
Onchocerca volvulus 0.0173 0.1897 0.4173
Echinococcus multilocularis neuropeptide s receptor 0.0561 0.6564 0.6672
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0073 0.0697 0.0708
Entamoeba histolytica cysteine proteinase, putative 0.0145 0.1565 1
Loa Loa (eye worm) hypothetical protein 0.0017 0.0027 0.0031
Schistosoma mansoni hypothetical protein 0.0017 0.0027 0.0027
Loa Loa (eye worm) hypothetical protein 0.0018 0.0036 0.0041
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0037 0.0263 0.0267
Loa Loa (eye worm) hypothetical protein 0.0017 0.0027 0.0031
Mycobacterium tuberculosis Cytochrome P450 121 Cyp121 0.0022 0.0083 0.0035
Schistosoma mansoni cercarial elastase (S01 family) 0.0018 0.0036 0.0036
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0037 0.0263 0.0267
Echinococcus granulosus programmed cell death protein 0.0018 0.004 0.0041
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0125 0.1319 0.2593
Toxoplasma gondii aspartyl protease ASP3 0.0183 0.2016 0.4402
Brugia malayi Calcium binding EGF domain containing protein 0.0017 0.0027 0.0031
Entamoeba histolytica papain family cysteine protease domain containing protein 0.0037 0.0261 0.1448
Schistosoma mansoni proteasome catalytic subunit 3 (T01 family) 0.0077 0.0744 0.0756
Plasmodium falciparum plasmepsin III 0.0023 0.0093 0.0265
Loa Loa (eye worm) cysteine protease 0.0145 0.1565 0.1819
Echinococcus granulosus cytochrome P450 2K1 0.0022 0.0083 0.0085
Loa Loa (eye worm) hypothetical protein 0.0101 0.1033 0.12
Trypanosoma cruzi cytochrome p450-like protein, putative 0.0022 0.0083 0.0087
Brugia malayi EF hand family protein 0.0019 0.0043 0.005
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0145 0.1565 0.4725
Echinococcus multilocularis calmodulin 0.0018 0.004 0.0041
Loa Loa (eye worm) MH2 domain-containing protein 0.0033 0.0222 0.0258
Trichomonas vaginalis lipid A export ATP-binding/permease protein msba, putative 0.0044 0.0344 0.094
Plasmodium falciparum plasmepsin VI 0.0023 0.0093 0.0265
Brugia malayi Chymotrypsin-like protease CTRL-1 precursor 0.0018 0.0036 0.0041
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0125 0.1319 0.2593
Plasmodium falciparum serine repeat antigen 8 0.0037 0.0261 0.1117
Mycobacterium ulcerans hypothetical protein 0.0029 0.0165 0.0129
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0023 0.0093 0.0094
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0145 0.1565 0.4725
Trypanosoma brucei Lanosterol 14-alpha demethylase 0.0022 0.0083 0.0095
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0019 0.0049 0.0057
Echinococcus multilocularis cathepsin d (lysosomal aspartyl protease) 0.0023 0.0093 0.0094
Echinococcus granulosus neurocalcin 0.0018 0.004 0.0041
Mycobacterium ulcerans cytochrome P450 140A5 Cyp140A5 0.0022 0.0083 0.0048
Schistosoma mansoni ap endonuclease 0.0019 0.0048 0.0049
Loa Loa (eye worm) hypothetical protein 0.0037 0.0261 0.0304
Schistosoma mansoni cathepsin D (A01 family) 0.0209 0.2337 0.2376
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0037 0.0261 0.0266
Loa Loa (eye worm) ctsf protein 0.0145 0.1565 0.1819
Trypanosoma brucei Calpain-like protein 1.2 0.0037 0.0271 0.0512
Echinococcus granulosus Mastin 0.0018 0.0036 0.0036
Plasmodium falciparum plasmepsin IX 0.0183 0.2016 1
Mycobacterium ulcerans hypothetical protein 0.0073 0.0697 0.0664
Plasmodium vivax SET domain protein, putative 0.0037 0.0263 0.1126
Schistosoma mansoni notch 0.0017 0.0027 0.0027
Trichomonas vaginalis Clan CA, family C2, calpain-like cysteine peptidase 0.0037 0.0271 0.0714
Echinococcus granulosus neuropeptide receptor A26 0.0561 0.6564 0.6672
Mycobacterium tuberculosis Probable protease II PtrBa [first part] (oligopeptidase B) 0.0352 0.4051 0.4022
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0037 0.0271 0.0512
Echinococcus granulosus calbindin 32 0.0019 0.0043 0.0044
Echinococcus multilocularis protein jagged 1 0.0017 0.0027 0.0027
Schistosoma mansoni rab 0.0018 0.004 0.0041
Trypanosoma cruzi hypothetical protein, conserved 0.0073 0.0697 0.1331
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0037 0.0271 0.0468
Mycobacterium ulcerans cytochrome P450 136A2 Cyp136A2 0.0022 0.0083 0.0048
Loa Loa (eye worm) MH2 domain-containing protein 0.049 0.5715 0.6641
Brugia malayi Cathepsin L-like precursor 0.0101 0.1037 0.1205
Onchocerca volvulus 0.0145 0.1565 0.3443
Loa Loa (eye worm) hypothetical protein 0.0017 0.0027 0.0031
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.009 0.0899 0.0914
Schistosoma mansoni family C2 unassigned peptidase (C02 family) 0.0331 0.3793 0.3856
Echinococcus multilocularis Transglutaminase 0.011 0.1143 0.1162
Trypanosoma cruzi importin beta-1 subunit, putative 0.0023 0.0101 0.0123
Toxoplasma gondii calmodulin CAM1 0.0019 0.0043 0.0037
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0029 0.0165 0.0129
Trypanosoma brucei cysteine peptidase, Clan CA, family C2, putative 0.0125 0.1319 0.2838
Entamoeba histolytica cysteine protease, putative 0.0081 0.079 0.4915
Mycobacterium tuberculosis Probable cytochrome P450 130 Cyp130 0.0022 0.0083 0.0035
Echinococcus multilocularis neuropeptide receptor A26 0.0561 0.6564 0.6672
Schistosoma mansoni hypothetical protein 0.0019 0.0049 0.005
Trypanosoma cruzi oligopeptidase B-like protein, putative 0.0156 0.17 0.3365
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.0081 0.079 0.0803
Trichomonas vaginalis Clan CA, family C2, calpain-like cysteine peptidase 0.0037 0.0271 0.0714
Trypanosoma cruzi cysteine peptidase, putative 0.0044 0.0349 0.0626
Loa Loa (eye worm) Papain cysteine protease/cathepsin propeptide inhibitor-containing protein 0.0145 0.1565 0.1819
Trypanosoma cruzi cysteine peptidase, putative 0.0145 0.1565 0.3093
Onchocerca volvulus Neurogenic locus notch homolog 0.0017 0.0027 0.0059
Plasmodium falciparum serine repeat antigen 1 0.0037 0.0261 0.1117
Giardia lamblia Hypothetical protein 0.011 0.1143 0.6603
Schistosoma mansoni cathepsin D (A01 family) 0.0209 0.2337 0.2376
Entamoeba histolytica P-glycoprotein-2 0.0044 0.0344 0.1989
Entamoeba histolytica P-glycoprotein-2 0.0044 0.0344 0.1989
Echinococcus granulosus peroxidasin 0.0173 0.1897 0.1929
Loa Loa (eye worm) fli-1 protein 0.0228 0.256 0.2975
Mycobacterium tuberculosis Probable cytochrome P450 139 Cyp139 0.0022 0.0083 0.0035
Brugia malayi Trypsin family protein 0.0018 0.0036 0.0041
Loa Loa (eye worm) calpain family protein 1 0.0243 0.2745 0.319
Giardia lamblia Cysteine protease 0.0037 0.0261 0.1387
Schistosoma mansoni family C2 unassigned peptidase (C02 family) 0.0349 0.4013 0.408
Trypanosoma brucei calpain-like protein, putative 0.0125 0.1319 0.2838
Loa Loa (eye worm) hypothetical protein 0.0293 0.3343 0.3884
Loa Loa (eye worm) hypothetical protein 0.0017 0.0027 0.0031
Onchocerca volvulus Slit protein homolog 0.0017 0.0027 0.0059
Giardia lamblia Encystation-specific protease 0.0037 0.0261 0.1387
Entamoeba histolytica cysteine protease, putative 0.0081 0.079 0.4915
Onchocerca volvulus 0.0101 0.1037 0.228
Trypanosoma cruzi conserved protein 0.0037 0.0271 0.0468
Brugia malayi calpain D 0.0037 0.0271 0.0315
Schistosoma mansoni ran 0.0021 0.0075 0.0076
Leishmania major oligopeptidase b 0.0156 0.17 0.3683
Trichomonas vaginalis Clan CA, family C2, calpain-like cysteine peptidase 0.0037 0.0271 0.0714
Schistosoma mansoni ef hand domain family member A2 0.0018 0.004 0.0041
Leishmania major cytoskeleton-associated protein CAP5.5, putative,cysteine peptidase, Clan CA, family C2, putative 0.0037 0.0271 0.0512
Echinococcus multilocularis notch 0.0017 0.0027 0.0027
Mycobacterium ulcerans cytochrome P450 125A7 Cyp125A7 0.0022 0.0083 0.0048
Echinococcus granulosus smad 0.0033 0.0222 0.0226
Trypanosoma cruzi cysteine peptidase C (CPC), putative 0.0158 0.1718 0.3402
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0019 0.005 0.0051
Echinococcus granulosus dipeptidyl aminopeptidaseprotein 0.0041 0.0316 0.0321
Brugia malayi prolyl oligopeptidase family protein 0.0041 0.0316 0.0367
Mycobacterium ulcerans cytochrome P450 185A4 Cyp185A4 0.004 0.0303 0.0269
Trypanosoma cruzi cruzipain precursor, putative 0.0044 0.0349 0.0626
Toxoplasma gondii LsmAD domain-containing protein 0.005 0.0417 0.0863
Schistosoma mansoni hypothetical protein 0.0019 0.0049 0.005
Brugia malayi MH2 domain containing protein 0.0033 0.0222 0.0258
Loa Loa (eye worm) hypothetical protein 0.0173 0.1897 0.2205
Onchocerca volvulus 0.0017 0.0027 0.0059
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0037 0.0261 0.0684
Loa Loa (eye worm) hypothetical protein 0.0331 0.3793 0.4408
Brugia malayi cytochrome P450 0.0022 0.0083 0.0097
Trichomonas vaginalis lipid A export ATP-binding/permease protein msba, putative 0.0044 0.0344 0.094
Echinococcus multilocularis calmodulin 0.0018 0.004 0.0041
Trypanosoma cruzi kinesin, putative 0.0087 0.0869 0.1679
Echinococcus multilocularis prolyl endopeptidase 0.0393 0.4546 0.4621
Plasmodium falciparum calpain 0.0037 0.0271 0.1167
Loa Loa (eye worm) animal heme peroxidase 0.0173 0.1897 0.2205
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.0081 0.079 0.0803
Loa Loa (eye worm) hypothetical protein 0.0173 0.1897 0.2205
Brugia malayi beta-lactamase family protein 0.0073 0.0697 0.081
Leishmania major 4-coumarate:coa ligase-like protein 0.0029 0.0165 0.0276
Trypanosoma brucei kinesin, putative 0.0087 0.0869 0.1838
Loa Loa (eye worm) hypothetical protein 0.0017 0.0027 0.0031
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0145 0.1565 0.4725
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0037 0.0271 0.0512
Trichomonas vaginalis Clan SC, family S9, acylaminoacyl-peptidase-like serine peptidase 0.0041 0.0316 0.0854
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0019 0.0049 0.005
Schistosoma mansoni notch 0.0017 0.0027 0.0027
Brugia malayi cathepsin L-like precursor 0.0101 0.1037 0.1205
Mycobacterium ulcerans cytochrome P450 143A3 Cyp143A3 0.0022 0.0083 0.0048
Echinococcus multilocularis ATP binding cassette subfamily B (MDR:TAP) 0.0044 0.0344 0.035
Toxoplasma gondii calpain family cysteine protease domain-containing protein 0.0037 0.0271 0.0541
Echinococcus granulosus cathepsin L 0.0037 0.0261 0.0266
Trypanosoma brucei Aph-1 protein, putative 0.0285 0.3244 0.711
Mycobacterium tuberculosis Hypothetical protein 0.011 0.1143 0.11
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0145 0.1565 0.4725
Echinococcus multilocularis geminin 0.0346 0.3976 0.4042
Mycobacterium tuberculosis Probable isocitrate dehydrogenase [NADP] Icd1 (oxalosuccinate decarboxylase) (IDH) (NADP+-specific ICDH) (IDP) 0.0019 0.005 0.0001
Brugia malayi Cathepsin L-like precursor 0.0044 0.0349 0.0406
Trypanosoma brucei calpain-like cysteine peptidase, putative 0.0125 0.1319 0.2838
Giardia lamblia Cathepsin L precursor 0.0037 0.0261 0.1387
Brugia malayi Peroxidasin 0.0173 0.1897 0.2205
Schistosoma mansoni smad1 5 8 and 0.0033 0.0222 0.0226
Plasmodium vivax serine-repeat antigen (SERA), putative 0.0037 0.0261 0.1117
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0037 0.0261 0.0684
Leishmania major calpain protease-like protein 0.0037 0.0271 0.0512
Echinococcus granulosus cpg binding protein 0.0037 0.0261 0.0265
Brugia malayi calpain family protein 1 0.0331 0.3793 0.4408
Giardia lamblia Cathepsin B precursor 0.0158 0.1718 1
Brugia malayi RNA, U transporter 1 0.0082 0.0804 0.0934
Trypanosoma cruzi mitogen activated protein kinase 2, putative 0.0049 0.0415 0.0759
Brugia malayi Importin beta-1 subunit 0.0029 0.0166 0.0193
Schistosoma mansoni neuronal calcium sensor 0.0018 0.004 0.0041
Echinococcus multilocularis subfamily S1A unassigned peptidase (S01 family) 0.0018 0.0036 0.0036
Plasmodium vivax vivapain-2 0.0145 0.1565 0.7717
Schistosoma mansoni survival motor neuron protein 0.0058 0.0521 0.0529
Trichomonas vaginalis Clan SC, family S33, methylesterase-like serine peptidase 0.0041 0.0316 0.0854
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0125 0.1319 0.2593
Plasmodium falciparum GTP-binding nuclear protein RAN/TC4 0.0021 0.0075 0.0175
Echinococcus granulosus cathepsin L cysteine proteinase 0.0145 0.1565 0.1591
Schistosoma mansoni serine/threonine protein kinase 0.0049 0.0415 0.0422
Plasmodium falciparum AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0019 0.0048 0.004
Schistosoma mansoni neuronal calcium sensor 0.0018 0.004 0.0041
Loa Loa (eye worm) hypothetical protein 0.0037 0.0271 0.0315
Entamoeba histolytica prolyl oligopeptidase family protein 0.0041 0.0316 0.1808
Echinococcus multilocularis neurocalcin 0.0018 0.004 0.0041
Schistosoma mansoni hypothetical protein 0.011 0.1143 0.1162
Loa Loa (eye worm) isocitrate dehydrogenase 0.0019 0.005 0.0058
Trypanosoma brucei PAB1-binding protein , putative 0.005 0.0417 0.0835
Schistosoma mansoni cercarial elastase (S01 family) 0.0018 0.0036 0.0036
Trypanosoma cruzi cytochrome P450, putative 0.004 0.0303 0.0533
Leishmania major ATP-binding cassette protein subfamily B, member 2, putative 0.0044 0.0344 0.0673
Giardia lamblia Cathepsin B-like cysteine proteinase 3 precursor 0.0037 0.0261 0.1387
Brugia malayi EGF-like domain containing protein 0.0017 0.0027 0.0031
Loa Loa (eye worm) hypothetical protein 0.0073 0.0697 0.081
Mycobacterium leprae Conserved hypothetical protein 0.011 0.1143 0.1069
Echinococcus granulosus Transglutaminase 0.011 0.1143 0.1162
Schistosoma mansoni ap endonuclease 0.0019 0.0048 0.0049
Plasmodium vivax hypothetical protein, conserved 0.0019 0.0043 0.0014
Leishmania major cathepsin L-like protease 0.0145 0.1565 0.3384
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD5 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.002 0.0064 0.0015
Onchocerca volvulus Peroxidase homolog 0.0173 0.1897 0.4173
Onchocerca volvulus 0.0018 0.0036 0.0079
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0037 0.0271 0.0512
Trypanosoma brucei hypothetical protein 0.0037 0.0271 0.0512
Toxoplasma gondii dipeptidyl peptidase iv (dpp iv) n-terminal region domain-containing protein 0.0041 0.0316 0.064
Trypanosoma brucei isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0019 0.005 0.0021
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0037 0.0261 0.0684
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0037 0.0271 0.0512
Trypanosoma cruzi Lanosterol 14-alpha demethylase 0.0022 0.0083 0.0087
Brugia malayi MH2 domain containing protein 0.0033 0.0222 0.0258
Trichomonas vaginalis calcineurin B subunit, putative 0.0019 0.0043 0.0009
Loa Loa (eye worm) hypothetical protein 0.0021 0.0078 0.009
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0125 0.1319 0.2593
Schistosoma mansoni SmCB2 peptidase (C01 family) 0.0428 0.4971 0.5053
Loa Loa (eye worm) gamma-secretase subunit aph-1 0.0731 0.8606 1
Trypanosoma cruzi isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0019 0.005 0.0019
Echinococcus granulosus slit 2 protein 0.0017 0.0027 0.0027
Brugia malayi MH1 domain containing protein 0.0018 0.0043 0.005
Echinococcus granulosus ATP binding cassette subfamily B MDR:TAP 0.0044 0.0344 0.035
Trypanosoma cruzi PAB1-binding protein , putative 0.005 0.0417 0.0763
Trichomonas vaginalis ATP-binding cassette transporter, putative 0.0044 0.0344 0.094
Schistosoma mansoni notch 0.0017 0.0027 0.0027
Loa Loa (eye worm) hypothetical protein 0.0037 0.0261 0.0304
Mycobacterium leprae Conserved hypothetical protein 0.011 0.1143 0.1069
Toxoplasma gondii cathepsin CPL 0.0145 0.1565 0.3404
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0037 0.0271 0.0512
Leishmania major proteasome beta 5 subunit, putative 0.0077 0.0744 0.1561
Trypanosoma cruzi hypothetical protein, conserved 0.0041 0.0316 0.0559
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0081 0.079 0.1663
Plasmodium vivax serine-repeat antigen (SERA) 0.0037 0.0261 0.1117
Toxoplasma gondii centrin, putative 0.0018 0.004 0.0031
Echinococcus granulosus neurogenic locus notch protein 0.0017 0.0027 0.0027
Loa Loa (eye worm) CXXC zinc finger family protein 0.0035 0.0237 0.0276
Loa Loa (eye worm) animal heme peroxidase 0.0173 0.1897 0.2205
Schistosoma mansoni cathepsin S (C01 family) 0.0037 0.0261 0.0266
Mycobacterium ulcerans transglutaminase family protein 0.011 0.1143 0.1112
Giardia lamblia Cathepsin L precursor 0.0037 0.0261 0.1387
Trypanosoma brucei calpain, putative 0.0037 0.0271 0.0512
Entamoeba histolytica acyl-CoA synthetase, putative 0.0029 0.0165 0.0814
Trichomonas vaginalis D-aminoacylase, putative 0.0073 0.0697 0.2034
Trichomonas vaginalis Clan AA, family A1, cathepsin D-like aspartic peptidase 0.0023 0.0093 0.0162
Mycobacterium ulcerans beta-lactamase 0.0073 0.0697 0.0664
Plasmodium falciparum proteasome subunit beta type-5 0.0077 0.0744 0.356
Trypanosoma brucei oligopeptidase b 0.0156 0.17 0.3683
Entamoeba histolytica acyl-CoA synthetase, putative 0.0029 0.0165 0.0814
Trypanosoma cruzi hypothetical protein, conserved 0.0041 0.0316 0.0559
Schistosoma mansoni hypothetical protein 0.0019 0.0049 0.005
Entamoeba histolytica hypothetical protein, conserved 0.0019 0.0043 0.0019
Schistosoma mansoni hypothetical protein 0.0346 0.3976 0.4042
Trypanosoma cruzi Present in the outer mitochondrial membrane proteome 33 0.0019 0.0043 0.0006
Trichomonas vaginalis ABC transporter, putative 0.0044 0.0344 0.094
Toxoplasma gondii cathepsin B 0.0158 0.1718 0.3742
Trichomonas vaginalis ABC transporter, half transporter, putative 0.0044 0.0344 0.094
Trypanosoma cruzi cytochrome P450, putative 0.004 0.0303 0.0533
Onchocerca volvulus Peroxidasin homolog 0.0173 0.1897 0.4173
Entamoeba histolytica P-glycoprotein-1 0.0044 0.0344 0.1989
Brugia malayi Delta serrate ligand family protein 0.0017 0.0027 0.0031
Schistosoma mansoni hypothetical protein 0.0017 0.0027 0.0027
Loa Loa (eye worm) Smad1 0.0033 0.0222 0.0258
Loa Loa (eye worm) hypothetical protein 0.0206 0.2295 0.2666
Leishmania major cathepsin L-like protease 0.0145 0.1565 0.3384
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0125 0.1319 0.2838
Echinococcus granulosus tumor protein p63 0.0689 0.8103 0.8237
Trypanosoma cruzi cysteine proteinase, putative 0.0081 0.079 0.152
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0018 0.0036 0.0036
Echinococcus granulosus GTP binding nuclear protein Ran 0.0021 0.0075 0.0076
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD35 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.002 0.0064 0.0015
Mycobacterium tuberculosis Probable cytochrome P450 124 Cyp124 0.0022 0.0083 0.0035
Trypanosoma cruzi cysteine peptidase, clan CA, family C1, cathepsin L-like, putative 0.0101 0.1037 0.202
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0145 0.1565 0.4725
Mycobacterium tuberculosis Probable lipase LipD 0.0073 0.0697 0.0652
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0145 0.1565 0.3384
Plasmodium falciparum serine repeat antigen 7 0.0037 0.0261 0.1117
Onchocerca volvulus 0.0206 0.2295 0.5047
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0037 0.0271 0.0468
Brugia malayi Trypsin family protein 0.0018 0.0036 0.0041
Onchocerca volvulus 0.0023 0.0093 0.0204
Echinococcus multilocularis dipeptidyl aminopeptidaseprotein 0.0041 0.0316 0.0321
Loa Loa (eye worm) hypothetical protein 0.0044 0.0349 0.0406
Giardia lamblia Cathepsin L precursor 0.0037 0.0261 0.1387
Echinococcus granulosus calpain 0.0125 0.1319 0.1341
Echinococcus granulosus multidrug resistance protein 1 0.003 0.0186 0.0189
Plasmodium falciparum serine repeat antigen 9 0.0037 0.0261 0.1117
Toxoplasma gondii GTP-binding nuclear protein ran/tc4 0.0021 0.0075 0.0107
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.0058 0.0521 0.0605
Giardia lamblia Hypothetical protein 0.0019 0.0043 0.0098
Brugia malayi Calcium binding EGF domain containing protein 0.0017 0.0027 0.0031
Loa Loa (eye worm) hypothetical protein 0.0043 0.0338 0.0393
Echinococcus granulosus family C2 unassigned peptidase C02 family 0.0349 0.4013 0.408
Loa Loa (eye worm) hypothetical protein 0.0173 0.1897 0.2205
Trypanosoma brucei cysteine peptidase, Clan CA, family C2, putative 0.0037 0.0271 0.0512
Toxoplasma gondii isocitrate dehydrogenase 0.0019 0.005 0.0051
Trichomonas vaginalis peptide N-glycanase, putative 0.011 0.1143 0.3417
Schistosoma mansoni hypothetical protein 0.0041 0.0315 0.032
Echinococcus granulosus cathepsin l1 0.0101 0.1037 0.1054
Trypanosoma brucei cysteine peptidase, Clan CA, family C2, putative 0.0037 0.0271 0.0512
Schistosoma mansoni centrin 0.0018 0.004 0.0041
Brugia malayi prolyl oligopeptidase family protein 0.0041 0.0316 0.0367
Loa Loa (eye worm) fibroinase 0.0145 0.1565 0.1819
Plasmodium vivax serine-repeat antigen 4 (SERA), putative 0.0037 0.0261 0.1117
Toxoplasma gondii preprocathepsin c precursor, putative 0.0037 0.0261 0.0519
Schistosoma mansoni hypothetical protein 0.0022 0.0088 0.0089
Echinococcus multilocularis neuronal calcium sensor 0.0018 0.004 0.0041
Brugia malayi Papain family cysteine protease containing protein 0.0037 0.0261 0.0304
Echinococcus granulosus calpain 7 C02 family 0.0125 0.1319 0.1341
Plasmodium vivax serine-repeat antigen 4 (SERA) 0.0037 0.0261 0.1117
Plasmodium falciparum acyl-CoA synthetase 0.0021 0.0078 0.0188
Entamoeba histolytica cysteine protease, putative 0.0081 0.079 0.4915
Loa Loa (eye worm) aspartic protease BmAsp-2 0.0023 0.0093 0.0108
Mycobacterium tuberculosis Probable conserved lipoprotein 0.0073 0.0697 0.0652
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0037 0.0271 0.0468
Mycobacterium ulcerans long-chain fatty-acid CoA ligase 0.0029 0.0165 0.0129
Onchocerca volvulus 0.0145 0.1565 0.3443
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0081 0.079 0.2322
Giardia lamblia Proteasome subunit beta type 5 precursor 0.0077 0.0744 0.424
Trichomonas vaginalis CMGC family protein kinase 0.0049 0.0415 0.116
Echinococcus granulosus glycoprotein Antigen 5 0.0018 0.0036 0.0036
Mycobacterium ulcerans cytochrome P450 188A3 Cyp188A3 0.0022 0.0083 0.0048
Brugia malayi hypothetical protein 0.005 0.0417 0.0484
Plasmodium vivax calpain, putative 0.0125 0.1319 0.6471
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0018 0.0036 0.0036
Brugia malayi Thioredoxin family protein 0.011 0.1143 0.1329
Schistosoma mansoni Mername-AA248 (C02 family) 0.0125 0.1319 0.1341
Toxoplasma gondii hypothetical protein 0.0037 0.0271 0.0541
Schistosoma mansoni hypothetical protein 0.0017 0.0027 0.0027
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0145 0.1565 0.4725
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.009 0.0899 0.0914
Plasmodium vivax vivapain-3 0.0081 0.079 0.3793
Loa Loa (eye worm) hypothetical protein 0.0017 0.0027 0.0031
Plasmodium vivax serine-repeat antigen (SERA) 0.0037 0.0261 0.1117
Echinococcus multilocularis atpase aaa+ type core atpase aaa type core 0.0819 0.9663 0.9823
Mycobacterium tuberculosis Probable esterase LipL 0.0073 0.0697 0.0652
Trichomonas vaginalis abcb9, putative 0.0044 0.0344 0.094
Schistosoma mansoni hypothetical protein 0.0017 0.0027 0.0027
Giardia lamblia GTP-binding nuclear protein RAN/TC4 0.0021 0.0075 0.0286
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0145 0.1565 0.3384
Brugia malayi beta-lactamase 0.0073 0.0697 0.081
Echinococcus granulosus Peptidase S1 S6 chymotrypsin Hap 0.0018 0.0036 0.0036
Schistosoma mansoni peroxidasin 0.0173 0.1897 0.1929
Brugia malayi Calmodulin-like protein 0.0018 0.004 0.0047
Loa Loa (eye worm) hypothetical protein 0.0393 0.4546 0.5282
Echinococcus granulosus transmembrane protease serine 3 0.0018 0.0036 0.0036
Leishmania major 4-coumarate:coa ligase-like protein 0.0029 0.0165 0.0276
Brugia malayi cathepsin L precursor 0.0037 0.0261 0.0304
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0037 0.0271 0.0512
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0037 0.0261 0.0684
Trypanosoma cruzi cysteine peptidase, putative 0.0145 0.1565 0.3093
Echinococcus granulosus cysteine protease 0.0081 0.079 0.0803
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0145 0.1565 0.3384
Loa Loa (eye worm) hypothetical protein 0.0017 0.0027 0.0031
Trichomonas vaginalis multidrug resistance protein 1, 2, putative 0.0044 0.0344 0.094
Leishmania major isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0019 0.005 0.0021
Mycobacterium ulcerans putative transglutaminase-like protein 0.011 0.1143 0.1112
Brugia malayi Papain family cysteine protease containing protein 0.0145 0.1565 0.1819
Onchocerca volvulus Cathepsin L homolog 0.0145 0.1565 0.3443
Trypanosoma brucei Calpain-like protein 2 0.0037 0.0271 0.0512
Echinococcus granulosus multidrug resistance protein 1 0.003 0.0186 0.0189
Schistosoma mansoni neuronal calcium sensor 0.0018 0.004 0.0041
Loa Loa (eye worm) ATP-binding cassette sub-family B member 2 0.0044 0.0344 0.04
Trypanosoma cruzi dipeptidyl-peptidase 8-like serine peptidase 0.0041 0.0316 0.0559
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0145 0.1565 0.3384
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0037 0.0261 0.0684
Brugia malayi MH2 domain containing protein 0.049 0.5715 0.6641
Loa Loa (eye worm) hypothetical protein 0.0021 0.0078 0.009
Loa Loa (eye worm) animal heme peroxidase 0.0173 0.1897 0.2205
Plasmodium vivax dipeptidyl aminopeptidase 2, putative 0.0037 0.0261 0.1117
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0145 0.1565 0.4725
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0037 0.0261 0.0684
Mycobacterium tuberculosis Proteasome beta subunit PrcB; assembles with alpha subunit PrcA. 0.0077 0.0744 0.0699
Plasmodium falciparum peptidase, putative 0.0041 0.0316 0.1395
Brugia malayi AMP-binding enzyme family protein 0.0029 0.0165 0.0191
Onchocerca volvulus Putative cubilin 0.0017 0.0027 0.0059
Onchocerca volvulus 0.0173 0.1897 0.4173
Brugia malayi Trypsin-like protease protein 5 0.0018 0.0036 0.0041
Giardia lamblia Cysteine protease 0.0037 0.0261 0.1387
Toxoplasma gondii ABC transporter transmembrane region domain-containing protein 0.0044 0.0344 0.0702
Echinococcus multilocularis cathepsin l cysteine peptidase 0.0145 0.1565 0.1591
Loa Loa (eye worm) hypothetical protein 0.0173 0.1897 0.2205
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0037 0.0261 0.0266
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0037 0.0271 0.0468
Entamoeba histolytica cysteine protease, putative 0.0037 0.0261 0.1448
Mycobacterium tuberculosis Fatty-acid-AMP ligase FadD30 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) 0.0021 0.0078 0.0029
Trichomonas vaginalis lipid A export ATP-binding/permease protein msba, putative 0.0044 0.0344 0.094
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0145 0.1565 0.4725
Trichomonas vaginalis Clan CA, family C2, calpain-like cysteine peptidase 0.0037 0.0271 0.0714
Echinococcus multilocularis glycoprotein Antigen 5 0.0018 0.0036 0.0036
Onchocerca volvulus 0.0145 0.1565 0.3443
Echinococcus multilocularis isocitrate dehydrogenase 2 (NADP+) 0.0019 0.005 0.0051
Trypanosoma cruzi cytoskeleton-associated protein CAP5.5, putative 0.0037 0.0271 0.0468
Echinococcus granulosus survival motor neuron protein 1 0.0286 0.3253 0.3307
Onchocerca volvulus 0.0023 0.0093 0.0204
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.009 0.0899 0.0914
Entamoeba histolytica cysteine proteinase 2 0.0081 0.079 0.4915
Brugia malayi MH1 domain containing protein 0.0018 0.0043 0.005
Plasmodium falciparum plasmepsin IV 0.0023 0.0093 0.0265
Echinococcus multilocularis cathepsin L cysteine protease 0.0145 0.1565 0.1591
Trypanosoma cruzi CAMK/CAMKL family protein kinase, putative 0.0019 0.0046 0.0011
Echinococcus granulosus proteasome prosome macropain 0.0077 0.0744 0.0756
Schistosoma mansoni calpain-7 (C02 family) 0.0128 0.1354 0.1376
Trichomonas vaginalis ap endonuclease, putative 0.0019 0.0048 0.0024
Trypanosoma brucei protein kinase, putative 0.0049 0.0415 0.0831
Loa Loa (eye worm) nucleolar RNA-associated protein alpha 0.0307 0.3513 0.4082
Brugia malayi Isocitrate dehydrogenase 0.0019 0.005 0.0058
Trypanosoma brucei importin beta-1 subunit, putative 0.0029 0.0166 0.0279
Echinococcus multilocularis calpain 0.0125 0.1319 0.1341
Loa Loa (eye worm) hypothetical protein 0.0173 0.1897 0.2205
Mycobacterium ulcerans cytochrome P450 108B4 Cyp108B4 0.0022 0.0083 0.0048
Loa Loa (eye worm) hypothetical protein 0.0173 0.1897 0.2205
Trichomonas vaginalis ap endonuclease, putative 0.0019 0.0048 0.0024
Echinococcus multilocularis ATP binding cassette sub family B 0.0043 0.0338 0.0344
Loa Loa (eye worm) hypothetical protein 0.0017 0.0027 0.0031
Echinococcus multilocularis microtubule associated protein 2 0.0833 0.9838 1
Giardia lamblia Endonuclease/Exonuclease/phosphatase 0.0019 0.0048 0.0128
Echinococcus granulosus calumenin 0.0019 0.0043 0.0044
Trypanosoma cruzi serine peptidase, Clan SC, Family S9B 0.0041 0.0316 0.0559
Trichomonas vaginalis Clan CA, family C2, calpain-like cysteine peptidase 0.0037 0.0271 0.0714
Brugia malayi Smad1 0.0033 0.0222 0.0258
Schistosoma mansoni calmodulin related calcium binding protein 0.0018 0.004 0.0041
Brugia malayi EGF-like domain containing protein 0.0017 0.0027 0.0031
Loa Loa (eye worm) hypothetical protein 0.0023 0.0093 0.0108
Loa Loa (eye worm) beta-lactamase 0.0073 0.0697 0.081
Brugia malayi Cytochrome P450 family protein 0.004 0.0303 0.0353
Schistosoma mansoni cell polarity protein 0.0017 0.0027 0.0027
Plasmodium falciparum serine repeat antigen 4 0.0037 0.0261 0.1117
Brugia malayi CXXC zinc finger family protein 0.0035 0.0237 0.0276
Trypanosoma brucei cysteine peptidase, Clan CA, family C2, putative 0.0037 0.0271 0.0512
Loa Loa (eye worm) hypothetical protein 0.0173 0.1897 0.2205
Echinococcus granulosus beta LACTamase domain containing family member 0.0073 0.0697 0.0708
Trichomonas vaginalis ABC transporter, putative 0.0044 0.0344 0.094
Loa Loa (eye worm) hypothetical protein 0.0173 0.1897 0.2205
Leishmania major calpain family cysteine protease-like protein 0.0037 0.0271 0.0512
Loa Loa (eye worm) aspartic protease BmAsp-1 0.0023 0.0093 0.0108
Schistosoma mansoni calpain C (C02 family) 0.0125 0.1319 0.1341
Toxoplasma gondii ABC1 family protein 0.0073 0.0697 0.1483
Schistosoma mansoni dipeptidyl-peptidase I (C01 family) 0.0037 0.0261 0.0266
Loa Loa (eye worm) nuclear factor I 0.0018 0.0043 0.005
Loa Loa (eye worm) CMGC/MAPK/ERK1 protein kinase 0.0049 0.0415 0.0482
Brugia malayi AMP-binding enzyme family protein 0.0029 0.0165 0.0191
Toxoplasma gondii hypothetical protein 0.0041 0.0316 0.064
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0037 0.0261 0.0684
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0145 0.1565 0.4725
Brugia malayi latrophilin 2 splice variant baaae 0.0041 0.0315 0.0366
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0145 0.1565 0.4725
Plasmodium vivax serine-repeat antigen 2 (SERA) 0.0037 0.0261 0.1117
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0023 0.0093 0.0094
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0023 0.0101 0.0187
Entamoeba histolytica hypothetical protein 0.0037 0.0261 0.1448
Mycobacterium tuberculosis Probable cytochrome P450 141 Cyp141 0.0022 0.0083 0.0035
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0037 0.0263 0.0523
Mycobacterium ulcerans cytochrome P450 51B1 Cyp51B1 0.0022 0.0083 0.0048
Loa Loa (eye worm) calpain 0.0125 0.1319 0.1533
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD7 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.002 0.0064 0.0015
Plasmodium vivax serine-repeat antigen 5 (SERA) 0.0037 0.0261 0.1117
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.0073 0.0697 0.0652
Brugia malayi prolyl oligopeptidase family protein 0.0393 0.4546 0.5282
Mycobacterium ulcerans cytochrome P450 150A6 Cyp150A6 0.0022 0.0083 0.0048
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.0021 0.0075 0.007
Onchocerca volvulus 0.0017 0.0027 0.0059
Loa Loa (eye worm) hypothetical protein 0.0021 0.0078 0.009
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0101 0.1037 0.3087
Onchocerca volvulus 0.0145 0.1565 0.3443
Schistosoma mansoni importin beta-1 0.0029 0.0166 0.0169
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0145 0.1565 0.3384
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0037 0.0261 0.0304
Loa Loa (eye worm) cysteine proteinase cathepsin Z 0.0037 0.0261 0.0304
Schistosoma mansoni cercarial elastase (S01 family) 0.0018 0.0036 0.0036
Plasmodium falciparum dipeptidyl aminopeptidase 2 0.0037 0.0261 0.1117
Brugia malayi Papain family cysteine protease containing protein 0.0037 0.0261 0.0304
Echinococcus multilocularis mitogen activated protein kinase 0.0049 0.0415 0.0422
Plasmodium vivax unspecified product 0.0081 0.079 0.3793
Trichomonas vaginalis conserved hypothetical protein 0.0037 0.0261 0.0684
Echinococcus multilocularis ATP binding cassette subfamily B (MDR:TAP) 0.0044 0.0344 0.035
Loa Loa (eye worm) hypothetical protein 0.0044 0.0344 0.04
Echinococcus granulosus fibropellin Ia 0.0017 0.0027 0.0027
Trypanosoma cruzi serine peptidase, clan SC, family S9A-like protein, putative 0.0156 0.17 0.3365
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0037 0.0261 0.0684
Plasmodium falciparum serine repeat antigen 6 0.0037 0.0261 0.1117
Trichomonas vaginalis ATP-binding cassette transporter, putative 0.0044 0.0344 0.094
Giardia lamblia Cathepsin L precursor 0.0037 0.0261 0.1387
Trypanosoma brucei importin beta-1 subunit, putative 0.0029 0.0166 0.0279
Treponema pallidum exodeoxyribonuclease (exoA) 0.0019 0.0048 0.5
Plasmodium falciparum dipeptidyl aminopeptidase 1 0.0037 0.0261 0.1117
Trypanosoma cruzi cysteine peptidase C (CPC), putative 0.0428 0.4971 1
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0037 0.0271 0.0512
Onchocerca volvulus 0.0058 0.0521 0.1145
Brugia malayi Cytochrome P450 family protein 0.0081 0.0792 0.092
Trypanosoma brucei serine peptidase, clan SC, family S9A-like protein 0.0156 0.17 0.3683
Leishmania major kinesin, putative 0.0087 0.0869 0.1838
Trichomonas vaginalis calpain, putative 0.0037 0.0271 0.0714
Plasmodium falciparum plasmepsin VII 0.0023 0.0093 0.0265
Echinococcus granulosus neuropeptide s receptor 0.0561 0.6564 0.6672
Mycobacterium tuberculosis Probable cytochrome P450 monooxygenase 142 Cyp142 0.0022 0.0083 0.0035
Loa Loa (eye worm) hypothetical protein 0.0018 0.0036 0.0041
Loa Loa (eye worm) hypothetical protein 0.0017 0.0027 0.0031
Brugia malayi Cytochrome P450 family protein 0.004 0.0303 0.0353
Echinococcus granulosus Dipeptidyl peptidase 9 0.0041 0.0316 0.0321
Toxoplasma gondii EF hand domain-containing protein 0.0018 0.004 0.0031
Toxoplasma gondii cathepsin CPC1 0.0037 0.0261 0.0519
Entamoeba histolytica cysteine protease, putative 0.0081 0.079 0.4915
Echinococcus granulosus TGF beta signal transducer SmadC 0.0033 0.0222 0.0226
Trypanosoma brucei calpain-like protein, putative 0.0125 0.1319 0.2838
Schistosoma mansoni smad1 5 8 and 0.0033 0.0222 0.0226
Trypanosoma brucei mitogen activated protein kinase 4, putative 0.0049 0.0415 0.0831
Leishmania major cathepsin L-like protease 0.0145 0.1565 0.3384
Leishmania major cytochrome p450-like protein 0.0022 0.0083 0.0095
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0018 0.0036 0.0036
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0035 0.0238 0.0242
Trypanosoma brucei Calpain-like protein CALP1.3 0.0037 0.0271 0.0512
Onchocerca volvulus 0.0073 0.0697 0.1533
Trichomonas vaginalis conserved hypothetical protein 0.0037 0.0261 0.0684
Schistosoma mansoni Sarcoplasmic calcium-binding protein (SCP). 0.0018 0.004 0.0041
Entamoeba histolytica cysteine protease, putative 0.0037 0.0261 0.1448
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0037 0.0261 0.0266
Schistosoma mansoni acylaminoacyl-peptidase (S09 family) 0.0041 0.0316 0.0321
Schistosoma mansoni cpg binding protein 0.0037 0.0261 0.0265
Onchocerca volvulus Cathepsin L homolog 0.0145 0.1565 0.3443
Trichomonas vaginalis ATP-binding cassette transporter, putative 0.0044 0.0344 0.094
Schistosoma mansoni reticulocalbin 0.0019 0.0043 0.0044
Onchocerca volvulus 0.0018 0.004 0.0089
Echinococcus granulosus neurogenic locus notch protein 0.0017 0.0027 0.0027
Plasmodium falciparum serine repeat antigen 2 0.0037 0.0261 0.1117
Echinococcus granulosus mitogen activated protein kinase 3 0.0049 0.0415 0.0422
Trypanosoma brucei GTP-binding nuclear protein rtb2, putative 0.0021 0.0075 0.0077
Leishmania major hypothetical protein, conserved 0.0019 0.0043 0.0006
Echinococcus granulosus delta-like protein 1 0.0017 0.0027 0.0027
Wolbachia endosymbiont of Brugia malayi exonuclease III 0.0019 0.0048 0.5
Onchocerca volvulus 0.0044 0.0344 0.0756
Giardia lamblia Dipeptidyl-peptidase I precursor 0.0037 0.0261 0.1387
Loa Loa (eye worm) GTP-binding nuclear protein RAN/TC4 0.0021 0.0075 0.0087
Trichomonas vaginalis lipid A export ATP-binding/permease protein msba, putative 0.0044 0.0344 0.094
Giardia lamblia Cathepsin B precursor 0.0037 0.0261 0.1387
Echinococcus multilocularis EF hand domain containing family member A2 0.0019 0.0043 0.0044
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.0019 0.0048 0.0056
Entamoeba histolytica P-glycoprotein-5 0.0044 0.0344 0.1989
Loa Loa (eye worm) proteasome A-type and B-type family protein 0.0077 0.0744 0.0864
Entamoeba histolytica cysteine protease, putative 0.0081 0.079 0.4915
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0023 0.0093 0.0094
Echinococcus multilocularis cysteine protease 0.0145 0.1565 0.1591
Echinococcus granulosus EF HAND 1 calcium binding site 0.0018 0.004 0.0041
Mycobacterium ulcerans hypothetical protein 0.011 0.1143 0.1112
Trypanosoma cruzi proteasome subunit beta type-5, putative 0.0077 0.0744 0.1426
Entamoeba histolytica P-glycoprotein 5, putative 0.0044 0.0344 0.1989
Plasmodium falciparum plasmepsin II 0.0023 0.0093 0.0265
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.0145 0.1565 0.4725
Schistosoma mansoni prolyl oligopeptidase (S09 family) 0.0041 0.0316 0.0321
Schistosoma mansoni prolyl oligopeptidase (S09 family) 0.0393 0.4546 0.4621
Loa Loa (eye worm) hypothetical protein 0.0018 0.0041 0.0047
Trypanosoma brucei antigen, putative 0.0125 0.1319 0.2838
Onchocerca volvulus 0.0145 0.1565 0.3443
Brugia malayi cahepsin L-like non-peptiedase homolog 0.0037 0.0261 0.0304
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD7 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0029 0.0165 0.0082
Trypanosoma cruzi cysteine peptidase, putative 0.0145 0.1565 0.3093
Giardia lamblia Cysteine protease 0.0037 0.0261 0.1387
Trypanosoma cruzi calpain cysteine peptidase, putative 0.0125 0.1319 0.2593
Brugia malayi calpain 7 0.0125 0.1319 0.1533
Echinococcus multilocularis transmembrane protease serine 3 0.0018 0.0036 0.0036
Brugia malayi Cadherin domain containing protein 0.0017 0.0027 0.0031
Toxoplasma gondii calcium-dependent protein kinase 0.0019 0.0049 0.0049
Loa Loa (eye worm) cathepsin B 0.0158 0.1718 0.1996
Brugia malayi Eukaryotic aspartyl protease family protein 0.0023 0.0093 0.0108
Brugia malayi multidrug resistance protein 3 0.0044 0.0344 0.04
Loa Loa (eye worm) hypothetical protein 0.0023 0.0093 0.0108
Entamoeba histolytica cysteine protease, putative 0.0081 0.079 0.4915
Entamoeba histolytica exodeoxyribonuclease III, putative 0.0019 0.0048 0.0052
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0037 0.0261 0.0266
Giardia lamblia Cathepsin L precursor 0.0037 0.0261 0.1387
Echinococcus granulosus multidrug resistance protein 1 0.0044 0.0344 0.035
Plasmodium falciparum isocitrate dehydrogenase [NADP], mitochondrial 0.0019 0.005 0.0047
Echinococcus multilocularis centrin 2 0.0018 0.004 0.0041
Brugia malayi cathepsin Z-like cysteine proteinase 0.0037 0.0261 0.0304
Echinococcus granulosus enteropeptidase 0.0018 0.0036 0.0036
Trypanosoma cruzi oligopeptidase b 0.0156 0.17 0.3365
Plasmodium falciparum ataxin-2 like protein, putative 0.005 0.0417 0.1905
Echinococcus multilocularis GA binding protein alpha chain 0.0075 0.0723 0.0735
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0023 0.0093 0.0094
Giardia lamblia Cathepsin L-like protease 0.0037 0.0261 0.1387
Loa Loa (eye worm) animal heme peroxidase 0.0173 0.1897 0.2205
Toxoplasma gondii cytochrome p450 superfamily protein 0.0022 0.0083 0.0125
Leishmania major 4-coumarate:coa ligase-like protein 0.0029 0.0165 0.0276
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0145 0.1565 0.3384
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0145 0.1565 0.3384
Trichomonas vaginalis multidrug resistance protein 1, 2, putative 0.0044 0.0344 0.094
Schistosoma mansoni hypothetical protein 0.0346 0.3976 0.4042
Brugia malayi ABC transporter family protein 0.0044 0.0344 0.04
Schistosoma mansoni Smad4 0.0033 0.0222 0.0226
Plasmodium vivax hypothetical protein, conserved 0.0041 0.0316 0.1395
Toxoplasma gondii ATP-binding cassette transporter ABC.B1 0.0044 0.0344 0.0702
Trichomonas vaginalis Clan CA, family C1, cathepsin L, S or H-like cysteine peptidase 0.0037 0.0261 0.0684
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.0073 0.0697 0.0664
Brugia malayi cathepsin Z-like cysteine proteinase 0.0037 0.0261 0.0304
Schistosoma mansoni smad1 5 8 and 0.0033 0.0222 0.0226
Trichomonas vaginalis ABC transporter, half transporter, putative 0.0044 0.0344 0.094
Echinococcus multilocularis cathepsin l cysteine peptidase 0.0145 0.1565 0.1591
Trypanosoma brucei Calpain-like protein 1.1 0.0037 0.0271 0.0512
Giardia lamblia Cathepsin B precursor 0.0158 0.1718 1
Schistosoma mansoni multidrug resistance protein 0.0044 0.0344 0.035
Echinococcus granulosus cathepsin L cysteine protease 0.0081 0.079 0.0803
Trichomonas vaginalis ABC transporter, putative 0.0044 0.0344 0.094
Entamoeba histolytica calpain family cysteine protease, putative 0.0037 0.0271 0.1512
Schistosoma mansoni hypothetical protein 0.0307 0.3513 0.3571
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0145 0.1565 0.4725
Loa Loa (eye worm) hypothetical protein 0.0073 0.0697 0.081
Echinococcus granulosus 5'partial|ATP binding cassette sub family B 0.0043 0.0338 0.0344
Mycobacterium tuberculosis Possible cytochrome P450 135A1 Cyp135A1 0.0022 0.0083 0.0035
Mycobacterium ulcerans acyl-CoA synthetase 0.0029 0.0165 0.0129
Loa Loa (eye worm) hypothetical protein 0.0073 0.0697 0.081
Schistosoma mansoni cercarial elastase (S01 family) 0.0018 0.0036 0.0036
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0145 0.1565 0.4725
Trypanosoma brucei cysteine peptidase C (CPC) 0.0158 0.1718 0.3723
Brugia malayi Calcium binding EGF domain containing protein 0.0017 0.0027 0.0031
Mycobacterium tuberculosis Probable cytochrome P450 128 Cyp128 0.0022 0.0083 0.0035
Echinococcus granulosus cathepsin b 0.0428 0.4971 0.5053
Echinococcus multilocularis cathepsin b 0.0428 0.4971 0.5053
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD3 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.002 0.0064 0.0015
Brugia malayi prolyl oligopeptidase family protein 0.0041 0.0316 0.0367
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0019 0.005 0.0051
Mycobacterium ulcerans cytochrome P450 187A5 Cyp187A5 0.0022 0.0083 0.0048
Trypanosoma brucei calpain-like protein, putative 0.0125 0.1319 0.2838
Echinococcus multilocularis family C2 unassigned peptidase (C02 family) 0.0349 0.4013 0.408
Entamoeba histolytica cysteine proteinase, putative 0.0145 0.1565 1
Echinococcus granulosus multidrug resistance protein 1 0.0044 0.0344 0.035
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0145 0.1565 0.3384
Mycobacterium ulcerans cytochrome P450 105Q4 Cyp105Q4 0.0022 0.0083 0.0048
Leishmania major calpain, putative,cysteine peptidase, Clan CA, family C2, putative 0.0125 0.1319 0.2838
Brugia malayi cathepsin B-like cysteine proteinase 0.0428 0.4971 0.5776
Giardia lamblia Transglutaminase/protease, putative 0.011 0.1143 0.6603
Plasmodium falciparum cysteine proteinase falcipain 2a 0.0145 0.1565 0.7717
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0037 0.0271 0.0468
Trichomonas vaginalis lipid A export ATP-binding/permease protein msba, putative 0.0044 0.0344 0.094
Entamoeba histolytica cysteine protease, putative 0.0145 0.1565 1
Leishmania major hypothetical protein, conserved 0.0037 0.0271 0.0512
Toxoplasma gondii eukaryotic aspartyl protease superfamily protein 0.0023 0.0093 0.0146
Mycobacterium ulcerans long-chain-fatty-acid--CoA ligase 0.0029 0.0165 0.0129
Brugia malayi Proteasome A-type and B-type family protein 0.0077 0.0744 0.0864
Leishmania major dipeptidyl-peptidase 8-like serine peptidase, putative,serine peptidase, Clan SC, Family S9B 0.0041 0.0316 0.0612
Echinococcus granulosus calpain A 0.0349 0.4016 0.4083
Echinococcus multilocularis cathepsin L 0.0081 0.079 0.0803
Brugia malayi prolyl oligopeptidase family protein 0.0041 0.0316 0.0367
Echinococcus multilocularis beta LACTamase domain containing family member 0.0073 0.0697 0.0708
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0019 0.0049 0.005
Schistosoma mansoni subfamily C1A non-peptidase homologue (C01 family) 0.0037 0.0261 0.0266
Loa Loa (eye worm) Notch2 0.0017 0.0027 0.0031
Loa Loa (eye worm) hypothetical protein 0.0037 0.0263 0.0305
Leishmania major hypothetical protein, conserved 0.0073 0.0697 0.1457
Echinococcus granulosus sarcoplasmic calcium binding protein 0.0018 0.004 0.0041
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD2 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0029 0.0165 0.0082
Giardia lamblia Alanyl dipeptidyl peptidase 0.0041 0.0316 0.1711
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0037 0.0263 0.0267
Echinococcus granulosus cathepsin b 0.0428 0.4971 0.5053
Echinococcus multilocularis Smad4 0.0033 0.0222 0.0226
Echinococcus multilocularis calpain 5 0.0125 0.1319 0.1341
Trypanosoma brucei cytochrome P450, putative 0.004 0.0303 0.0584
Loa Loa (eye worm) hypothetical protein 0.0017 0.0027 0.0031
Mycobacterium ulcerans esterase/lipase LipP 0.0073 0.0697 0.0664
Loa Loa (eye worm) hypothetical protein 0.0023 0.0093 0.0108
Loa Loa (eye worm) hypothetical protein 0.0173 0.1897 0.2205
Brugia malayi hypothetical protein 0.0286 0.3253 0.378
Trypanosoma cruzi Aph-1 protein, putative 0.0285 0.3244 0.6497
Trichomonas vaginalis conserved hypothetical protein 0.0041 0.0316 0.0854
Toxoplasma gondii aspartyl protease 0.0023 0.0093 0.0146
Trichomonas vaginalis multidrug resistance protein 1, 2, putative 0.0044 0.0344 0.094
Plasmodium vivax dipeptidyl aminopeptidase 1, putative 0.0037 0.0261 0.1117
Leishmania major cathepsin L-like protease 0.0145 0.1565 0.3384
Onchocerca volvulus 0.0073 0.0697 0.1533
Loa Loa (eye worm) hypothetical protein 0.0018 0.0036 0.0041
Echinococcus granulosus dnaJ subfamily B 0.0494 0.5758 0.5853
Mycobacterium tuberculosis Probable cytochrome P450 123 Cyp123 0.0022 0.0083 0.0035
Mycobacterium tuberculosis Possible cytochrome P450 126 Cyp126 0.0022 0.0083 0.0035
Echinococcus granulosus EF hand domain containing family member A2 0.0019 0.0043 0.0044
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0037 0.0271 0.0468
Trypanosoma cruzi PAB1-binding protein , putative 0.005 0.0417 0.0763
Schistosoma mansoni calpain (C02 family) 0.0125 0.1319 0.1341
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0023 0.0101 0.0187
Trichomonas vaginalis multidrug resistance protein 1, 2, putative 0.0044 0.0344 0.094
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0023 0.0093 0.0094
Loa Loa (eye worm) hypothetical protein 0.0073 0.0697 0.081
Trypanosoma cruzi Aph-1 protein, putative 0.0285 0.3244 0.6497
Loa Loa (eye worm) hypothetical protein 0.0017 0.0027 0.0031
Brugia malayi Papain family cysteine protease containing protein 0.0081 0.079 0.0918
Schistosoma mansoni multidrug resistance protein 0.0044 0.0344 0.035
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0037 0.0271 0.0468
Loa Loa (eye worm) calmodulin-like protein 0.0018 0.004 0.0047
Mycobacterium ulcerans proteasome PrcB 0.0077 0.0744 0.0711
Echinococcus multilocularis multidrug resistance protein 1 0.003 0.0186 0.0189
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0075 0.0721 0.0733
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.0019 0.0048 0.0049
Leishmania major cathepsin L-like protease 0.0145 0.1565 0.3384
Loa Loa (eye worm) hypothetical protein 0.0286 0.3253 0.378
Mycobacterium tuberculosis Cytochrome P450 51 Cyp51 (CYPL1) (P450-L1A1) (sterol 14-alpha demethylase) (lanosterol 14-alpha demethylase) (P450-14DM) 0.0022 0.0083 0.0035
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0037 0.0271 0.0468
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0023 0.0093 0.0094
Onchocerca volvulus 0.0017 0.0027 0.0059
Schistosoma mansoni cytochrome P450 0.0022 0.0083 0.0085
Echinococcus granulosus calpain A 0.0125 0.1319 0.1341
Schistosoma mansoni calpain-7 (C02 family) 0.0128 0.1354 0.1376
Loa Loa (eye worm) hypothetical protein 0.0037 0.0261 0.0304
Entamoeba histolytica cysteine proteinase, putative 0.0081 0.079 0.4915
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0018 0.0036 0.0036
Brugia malayi Ets-domain containing protein 0.0075 0.0723 0.084
Echinococcus multilocularis sarcoplasmic calcium binding protein 0.0018 0.004 0.0041
Schistosoma mansoni calmodulin 0.0018 0.004 0.0041
Schistosoma mansoni neuronal calcium sensor 0.0018 0.004 0.0041
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0037 0.0271 0.0512
Schistosoma mansoni subfamily S9B unassigned peptidase (S09 family) 0.0041 0.0316 0.0321
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0428 0.4971 0.5053
Mycobacterium tuberculosis Conserved hypothetical protein 0.011 0.1143 0.11
Brugia malayi hypothetical protein 0.0173 0.1897 0.2205
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0145 0.1565 0.4725
Plasmodium falciparum cysteine proteinase falcipain 1 0.0081 0.079 0.3793
Brugia malayi Animal haem peroxidase family protein 0.0173 0.1897 0.2205
Echinococcus multilocularis calpain A 0.0349 0.4016 0.4083
Mycobacterium tuberculosis Probable protease II PtrBb [second part] (oligopeptidase B) 0.0156 0.17 0.1659
Trypanosoma brucei calpain-like cysteine peptidase, putative 0.0037 0.0271 0.0512
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0019 0.0049 0.005
Brugia malayi Cathepsin L-like precursor 0.0145 0.1565 0.1819
Loa Loa (eye worm) hypothetical protein 0.0044 0.0349 0.0406
Toxoplasma gondii troponin c, isotype gamma, putative 0.0018 0.004 0.0031
Schistosoma mansoni laminin gamma-3 chain 0.0017 0.0027 0.0027
Echinococcus granulosus Ataxin 2 N terminaldomain containing protein 0.0022 0.0088 0.0089
Echinococcus granulosus calpain 5 0.0125 0.1319 0.1341
Trypanosoma brucei glucosamine 6-phosphate n-acetyltransferase 0.0037 0.0271 0.0512
Mycobacterium tuberculosis Long conserved protein 0.011 0.1143 0.11
Loa Loa (eye worm) hypothetical protein 0.0017 0.0027 0.0031
Leishmania major hypothetical protein, conserved 0.005 0.0417 0.0835
Mycobacterium leprae proteasome (beta subunit) PrcB 0.0077 0.0744 0.0666
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0037 0.0263 0.0267
Trichomonas vaginalis calmodulin, putative 0.0019 0.0043 0.0009
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.009 0.0899 0.0914
Echinococcus multilocularis survival motor neuron protein 1 0.0286 0.3253 0.3307
Giardia lamblia Kinase, CMGC MAPK 0.0049 0.0415 0.2295
Schistosoma mansoni mitochondrial solute carrier 0.0018 0.004 0.0041
Schistosoma mansoni cathepsin B (C01 family) 0.0037 0.0261 0.0266
Trypanosoma brucei proteasome subunit beta type-5, putative 0.0077 0.0744 0.1561
Brugia malayi cathepsin L-like cysteine proteinase, identical 0.0044 0.0349 0.0406
Loa Loa (eye worm) hypothetical protein 0.0017 0.0027 0.0031
Loa Loa (eye worm) hypothetical protein 0.0029 0.0166 0.0193
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0037 0.0271 0.0468
Onchocerca volvulus 0.0018 0.004 0.0089
Loa Loa (eye worm) hypothetical protein 0.0017 0.0027 0.0031
Echinococcus multilocularis cysteine protease 0.0145 0.1565 0.1591
Toxoplasma gondii acylaminoacyl-peptidase, putative 0.0041 0.0316 0.064
Echinococcus granulosus neurogenic locus protein delta 0.0017 0.0027 0.0027
Echinococcus granulosus geminin 0.0346 0.3976 0.4042
Schistosoma mansoni cathepsin F (C01 family) 0.0101 0.1037 0.1054
Loa Loa (eye worm) hypothetical protein 0.0173 0.1897 0.2205
Trichomonas vaginalis penicillin-binding protein, putative 0.0073 0.0697 0.2034

Activities

Activity type Activity value Assay description Source Reference
Potency (functional) 1.5849 uM PubChem BioAssay. qHTS for Activators of Integrin-Mediated Alleviation for Muscular Dystrophy. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) = 3.1623 um PUBCHEM_BIOASSAY: qHTS Assay for Enhancers of SMN2 Splice Variant Expression. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) = 3.9811 um PUBCHEM_BIOASSAY: qHTS Inhibitors of AmpC Beta-Lactamase (assay with detergent). (Class of assay: confirmatory) [Related pubchem assays: 1002 (Confirmation Concentration-Response Assay for Inhibitors of AmpC Beta-Lactamase (assay with detergent)), 585 (Promiscuous and Specific Inhibitors of AmpC Beta-Lactamase (assay without detergent) - a screen old NIH MLSMR collection), 584 (Promiscuous and Specific Inhibitors of AmpC Beta-Lactamase (assay with detergent) - a screen of the old NIH MLSMR collection), 1003 (Confirmation Cuvette-Based Assay for Inhibitors of AmpC Beta-Lactamase (assay with detergent))] ChEMBL. No reference
Potency (functional) = 5.0119 um PUBCHEM_BIOASSAY: qHTS Assay for Inhibitors Targeting the Menin-MLL Interaction in MLL Related Leukemias: Competition With Texas Red Labeled MLL-derived Mutant Peptide. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) 6.5131 uM PubChem BioAssay. A quantitative high throughput screen for small molecules that induce DNA re-replication in MCF 10a normal breast cells. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) 8.2753 uM PUBCHEM_BIOASSAY: Primary qHTS for delayed death inhibitors of the malarial parasite plastid, 48 hour incubation. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID488752, AID488774, AID504848, AID504850] ChEMBL. No reference
Potency (functional) 10 uM PubChem BioAssay. qHTS of GLP-1 Receptor Inverse Agonists (Inhibition Mode). (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) = 12.5893 um PUBCHEM_BIOASSAY: qHTS Assay for Antagonists of the Neuropeptide S Receptor: cAMP Signal Transduction. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) 18.3564 uM PubChem BioAssay. qHTS for induction of synthetic lethality in tumor cells producing 2HG: qHTS for the HT-1080-NT fibrosarcoma cell line. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) 19.0115 uM PUBCHEM_BIOASSAY: qHTS profiling assay for firefly luciferase inhibitor/activator using purified enzyme and Km concentrations of substrates (counterscreen for miR-21 project). (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID2288, AID2289, AID2598, AID411] ChEMBL. No reference
Potency (functional) = 19.9526 um PUBCHEM_BIOASSAY: Counterscreen qHTS for Inhibitors of Tau Fibril Formation, Fluorescence Polarization. This assay monitors tau fibrillation by fluorescence polarization (FP) of Alexa 594-labeled K18 P301L, which does not fibrillize readily but incorporates into growing filaments of unlabeled tau. (Class of assay: confirmatory) [Related pubchem assays: 596 ] ChEMBL. No reference
Potency (functional) 19.9526 uM PUBCHEM_BIOASSAY: qHTS Assay for Inhibitors of Histone Lysine Methyltransferase G9a. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID504404] ChEMBL. No reference
Potency (functional) = 25.1189 um PUBCHEM_BIOASSAY: qHTS for inhibitors of ROR gamma transcriptional activity. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) 25.1189 uM PUBCHEM_BIOASSAY: qHTS for Inhibitors of binding or entry into cells for Lassa Virus. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID463114, AID540249] ChEMBL. No reference
Potency (functional) 25.929 uM PUBCHEM_BIOASSAY: qHTS screen for small molecules that inhibit ELG1-dependent DNA repair in human embryonic kidney (HEK293T) cells expressing luciferase-tagged ELG1. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID493107, AID493125] ChEMBL. No reference
Potency (binding) = 28.1838 um PUBCHEM_BIOASSAY: qHTS for Inhibitors of Tau Fibril Formation, Thioflavin T Binding. (Class of assay: confirmatory) [Related pubchem assays: 596 ] ChEMBL. No reference
Potency (functional) 29.0929 uM PUBCHEM_BIOASSAY: Nrf2 qHTS screen for inhibitors. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID493153, AID493163, AID504648] ChEMBL. No reference
Potency (functional) 31.6228 uM PubChem BioAssay. qHTS of TDP-43 Inhibitors. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) = 35.4813 um PUBCHEM_BIOASSAY: qHTS Multiplex Assay to Identify Dual Action Probes in a Cell Model of Huntington: Aggregate Formation (GFP). (Class of assay: confirmatory) [Related pubchem assays: 1482, 1471 ] ChEMBL. No reference
Potency (functional) 35.4813 uM PUBCHEM_BIOASSAY: qHTS for Inhibitors of TGF-b. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID588856, AID588860] ChEMBL. No reference
Potency (functional) 35.4813 uM PubChem BioAssay. qHTS of alpha-syn Inhibitors. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) = 35.4813 um PUBCHEM_BIOASSAY: qHTS Assay for Small Molecule Inhibitors of Mitochondrial Division or Activators of Mitochondrial Fusion. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) 39.8107 uM PUBCHEM_BIOASSAY: qHTS Assay for Inhibitors of BAZ2B. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID504391] ChEMBL. No reference
Potency (functional) 44.6684 uM PUBCHEM_BIOASSAY: HTS for Inhibitors of HP1-beta Chromodomain Interactions with Methylated Histone Tails. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID488962] ChEMBL. No reference
Potency (functional) 50.1187 uM PubChem BioAssay. qHTS for Antagonists of gsp, the Etiologic Mutation Responsible for Fibrous Dysplasia/McCune-Albright Syndrome: qHTS. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) 89.1251 uM PUBCHEM_BIOASSAY: qHTS for Inhibitors of Polymerase Iota. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID588623] ChEMBL. No reference

Phenotypes

Whole-cell/tissue/organism interactions

Species name Source Reference Is orphan
Plasmodium falciparum ChEMBL23

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

Bibliographic References

No literature references available for this target.

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