Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Echinococcus multilocularis | aldo keto reductase family 1, member B4 | 0.0101 | 0.4632 | 0.4542 |
Schistosoma mansoni | aldehyde dehydrogenase | 0.0067 | 0.2709 | 0.2604 |
Schistosoma mansoni | growth factor receptor-bound protein | 0.0164 | 0.8136 | 0.8109 |
Treponema pallidum | ATP-dependent Clp protease proteolytic subunit | 0.0084 | 0.3632 | 1 |
Echinococcus multilocularis | tyrosine protein kinase Src42A | 0.005 | 0.178 | 0.1641 |
Loa Loa (eye worm) | SRC-1 | 0.0071 | 0.295 | 0.3493 |
Echinococcus granulosus | aldo keto reductase family 1 member B4 | 0.0101 | 0.4632 | 0.4542 |
Echinococcus granulosus | tyrosine protein kinase Btk29A | 0.0039 | 0.1143 | 0.0993 |
Echinococcus granulosus | tyrosine protein kinase Fyn | 0.0071 | 0.295 | 0.2831 |
Toxoplasma gondii | oxidoreductase, aldo/keto reductase family protein | 0.0029 | 0.0611 | 0.0084 |
Brugia malayi | Variant SH3 domain containing protein | 0.0035 | 0.0949 | 0.1133 |
Echinococcus multilocularis | aldo keto reductase family 1, member B4 | 0.0101 | 0.4632 | 0.4542 |
Brugia malayi | oxidoreductase, aldo/keto reductase family protein | 0.0101 | 0.4632 | 0.5678 |
Mycobacterium leprae | Possible oxidoreductase | 0.0029 | 0.0611 | 0.0084 |
Echinococcus granulosus | tyrosine protein kinase Lyn | 0.0072 | 0.2977 | 0.2859 |
Echinococcus granulosus | aldehyde dehydrogenase mitochondrial | 0.0067 | 0.2709 | 0.2585 |
Entamoeba histolytica | protein kinase, putative | 0.0095 | 0.4291 | 0.9263 |
Mycobacterium leprae | Conserved hypothetical protein | 0.0072 | 0.2993 | 0.5956 |
Schistosoma mansoni | tyrosine kinase | 0.0021 | 0.0166 | 0.0025 |
Trypanosoma cruzi | aldo/keto reductase, putative | 0.0101 | 0.4632 | 1 |
Entamoeba histolytica | aldose reductase, putative | 0.0101 | 0.4632 | 1 |
Leishmania major | aldehyde dehydrogenase, mitochondrial precursor | 0.0067 | 0.2709 | 0.5216 |
Trichomonas vaginalis | aldo-keto reductase, putative | 0.0101 | 0.4632 | 1 |
Trypanosoma cruzi | PAB1-binding protein , putative | 0.0029 | 0.0612 | 0.0002 |
Brugia malayi | oxidoreductase, aldo/keto reductase family protein | 0.0101 | 0.4632 | 0.5678 |
Leishmania major | serine/threonine-protein kinase, putative,protein kinase, putative | 0.0095 | 0.4291 | 0.9151 |
Toxoplasma gondii | aldose reductase, putative | 0.0101 | 0.4632 | 1 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0099 | 0.4501 | 0.4408 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0099 | 0.4501 | 0.4408 |
Echinococcus multilocularis | tyrosine protein kinase lyn lyn a protein tyrosine kinase lymphocyte specific protein tyrosine kinase | 0.0071 | 0.295 | 0.2831 |
Echinococcus multilocularis | ATP dependent Clp protease proteolytic subunit | 0.0084 | 0.3632 | 0.3525 |
Trichomonas vaginalis | aldo-keto reductase, putative | 0.0101 | 0.4632 | 1 |
Echinococcus multilocularis | tyrosine protein kinase Abl | 0.0039 | 0.1143 | 0.0993 |
Echinococcus granulosus | peptidase Clp S14 family | 0.0055 | 0.2027 | 0.1892 |
Echinococcus multilocularis | geminin | 0.0198 | 1 | 1 |
Mycobacterium tuberculosis | Probable ATP-dependent CLP protease proteolytic subunit 1 ClpP1 (endopeptidase CLP) | 0.0055 | 0.2027 | 0.352 |
Schistosoma mansoni | jumonji/arid domain-containing protein | 0.0065 | 0.2591 | 0.2485 |
Entamoeba histolytica | hypothetical protein | 0.0095 | 0.4291 | 0.9263 |
Schistosoma mansoni | aldo-keto reductase | 0.0101 | 0.4632 | 0.4555 |
Trichomonas vaginalis | aldo-keto reductase, putative | 0.0101 | 0.4632 | 1 |
Schistosoma mansoni | pol-related | 0.0101 | 0.4632 | 0.4555 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0099 | 0.4501 | 0.4423 |
Onchocerca volvulus | 0.0101 | 0.4632 | 1 | |
Schistosoma mansoni | jumonji/arid domain-containing protein | 0.0065 | 0.2591 | 0.2485 |
Echinococcus multilocularis | aldo keto reductase | 0.0101 | 0.4632 | 0.4542 |
Echinococcus granulosus | aldehyde reductase | 0.0072 | 0.2993 | 0.2874 |
Echinococcus granulosus | tyrosine protein kinase Fyn | 0.0071 | 0.295 | 0.2831 |
Leishmania major | hypothetical protein, conserved | 0.0029 | 0.0612 | 0.0002 |
Schistosoma mansoni | serine/threonine protein kinase | 0.0095 | 0.4291 | 0.4209 |
Echinococcus granulosus | aldo keto reductase family 1 member B4 | 0.0101 | 0.4632 | 0.4542 |
Echinococcus granulosus | ATP dependent Clp protease proteolytic subunit | 0.0084 | 0.3632 | 0.3525 |
Mycobacterium tuberculosis | Probable aldehyde dehydrogenase | 0.0067 | 0.2709 | 0.5216 |
Loa Loa (eye worm) | TK protein kinase | 0.0054 | 0.1974 | 0.2268 |
Echinococcus multilocularis | tyrosine protein kinase Src64B | 0.0071 | 0.295 | 0.2831 |
Echinococcus granulosus | hypothetical protein | 0.0101 | 0.4632 | 0.4542 |
Trichomonas vaginalis | cat eye syndrome critical region protein 2, cscr2, putative | 0.0046 | 0.1512 | 0.224 |
Echinococcus granulosus | tyrosine kinase | 0.0054 | 0.1974 | 0.1838 |
Schistosoma mansoni | growth factor receptor-bound protein | 0.0164 | 0.8136 | 0.8109 |
Echinococcus granulosus | growth factor receptor bound protein 2 | 0.0164 | 0.8136 | 0.8104 |
Echinococcus granulosus | aldo keto reductase family 1, member B4 | 0.0029 | 0.0611 | 0.0452 |
Trichomonas vaginalis | aldo-keto reductase, putative | 0.0101 | 0.4632 | 1 |
Brugia malayi | jmjC domain containing protein | 0.0065 | 0.2591 | 0.3159 |
Loa Loa (eye worm) | hypothetical protein | 0.0084 | 0.3632 | 0.4349 |
Loa Loa (eye worm) | glutamate-cysteine ligase modifier subunit | 0.0029 | 0.0611 | 0.0558 |
Loa Loa (eye worm) | oxidoreductase | 0.0101 | 0.4632 | 0.5604 |
Loa Loa (eye worm) | hypothetical protein | 0.0095 | 0.4263 | 0.5141 |
Echinococcus multilocularis | proto oncogene tyrosine protein kinase LCK | 0.0071 | 0.295 | 0.2831 |
Schistosoma mansoni | tyrosine kinase | 0.0021 | 0.0166 | 0.0025 |
Mycobacterium tuberculosis | Probable ATP-dependent CLP protease proteolytic subunit 2 ClpP2 (endopeptidase CLP 2) | 0.0055 | 0.2027 | 0.352 |
Echinococcus multilocularis | gcn5proteinral control of amino acid synthesis | 0.0155 | 0.761 | 0.757 |
Loa Loa (eye worm) | oxidoreductase | 0.0101 | 0.4632 | 0.5604 |
Brugia malayi | hypothetical protein | 0.0021 | 0.0166 | 0.0167 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0099 | 0.4501 | 0.4408 |
Onchocerca volvulus | 0.0101 | 0.4632 | 1 | |
Leishmania major | aldehyde reductase, putative,oxidoreductase, putative | 0.0101 | 0.4632 | 1 |
Brugia malayi | Protein kinase domain containing protein | 0.0021 | 0.0166 | 0.0167 |
Echinococcus granulosus | aldo keto reductase family 1 member B4 | 0.0101 | 0.4632 | 0.4542 |
Trichomonas vaginalis | aldo/keto reductase, putative | 0.0101 | 0.4632 | 1 |
Plasmodium falciparum | ataxin-2 like protein, putative | 0.0029 | 0.0612 | 0.0113 |
Plasmodium vivax | oxidoreductase, aldo/keto reductase domain containing protein | 0.0029 | 0.0611 | 0.0111 |
Echinococcus multilocularis | tyrosine protein kinase lyn tyrosine protein kinase blk | 0.0071 | 0.295 | 0.2831 |
Brugia malayi | SH2 domain containing protein | 0.0021 | 0.0166 | 0.0167 |
Entamoeba histolytica | protein kinase domain containing protein | 0.0095 | 0.4291 | 0.9263 |
Brugia malayi | oxidoreductase, aldo/keto reductase family protein | 0.0101 | 0.4632 | 0.5678 |
Plasmodium falciparum | histone acetyltransferase GCN5 | 0.0042 | 0.13 | 0.2366 |
Schistosoma mansoni | aldehyde dehydrogenase | 0.0067 | 0.2709 | 0.2604 |
Trichomonas vaginalis | dihydrodiol dehydrogenase, putative | 0.0101 | 0.4632 | 1 |
Chlamydia trachomatis | ATP-dependent Clp protease proteolytic subunit | 0.0084 | 0.3632 | 0.5 |
Echinococcus granulosus | aldo keto reductase family 1 member B4 | 0.0101 | 0.4632 | 0.4542 |
Trichomonas vaginalis | aldo-keto reductase, putative | 0.0101 | 0.4632 | 1 |
Loa Loa (eye worm) | variant SH3 domain-containing protein | 0.0035 | 0.0949 | 0.0982 |
Brugia malayi | glutamate-cysteine ligase modifier subunit | 0.0029 | 0.0611 | 0.0716 |
Echinococcus granulosus | aldo keto reductase | 0.0101 | 0.4632 | 0.4542 |
Echinococcus multilocularis | aldo keto reductase family 1, member B4 | 0.0101 | 0.4632 | 0.4542 |
Echinococcus granulosus | dual specificity | 0.0095 | 0.4291 | 0.4194 |
Echinococcus multilocularis | growth factor receptor bound protein 2 | 0.0164 | 0.8136 | 0.8104 |
Trypanosoma brucei | aldo-keto reductase, putative | 0.0101 | 0.4632 | 1 |
Onchocerca volvulus | 0.0029 | 0.0611 | 0.0996 | |
Echinococcus granulosus | aldo keto reductase | 0.0101 | 0.4632 | 0.4542 |
Mycobacterium leprae | PROBABLE OXIDOREDUCTASE | 0.0101 | 0.4632 | 1 |
Schistosoma mansoni | hypothetical protein | 0.0198 | 1 | 1 |
Loa Loa (eye worm) | acetyltransferase | 0.0155 | 0.761 | 0.9341 |
Echinococcus granulosus | histone acetyltransferase KAT2B | 0.015 | 0.7368 | 0.7324 |
Schistosoma mansoni | gcn5proteinral control of amino-acid synthesis 5-like 2 gcnl2 | 0.0155 | 0.761 | 0.7576 |
Giardia lamblia | Aldose reductase | 0.0101 | 0.4632 | 1 |
Wolbachia endosymbiont of Brugia malayi | ATP-dependent Clp protease proteolytic subunit | 0.0084 | 0.3632 | 0.5 |
Trichomonas vaginalis | aldo/keto reductase, putative | 0.0101 | 0.4632 | 1 |
Trichomonas vaginalis | aldo-keto reductase, putative | 0.0101 | 0.4632 | 1 |
Plasmodium falciparum | ataxin-2 like protein, putative | 0.0029 | 0.0612 | 0.0113 |
Trichomonas vaginalis | aldo/keto reductase, putative | 0.0101 | 0.4632 | 1 |
Plasmodium vivax | histone acetyltransferase GCN5, putative | 0.0046 | 0.1512 | 0.3059 |
Trichomonas vaginalis | aldo-keto reductase, putative | 0.0101 | 0.4632 | 1 |
Brugia malayi | oxidoreductase, aldo/keto reductase family protein | 0.0101 | 0.4632 | 0.5678 |
Brugia malayi | hypothetical protein | 0.0029 | 0.0612 | 0.0717 |
Echinococcus multilocularis | aldo keto reductase family 1, member B4 | 0.0101 | 0.4632 | 0.4542 |
Trypanosoma brucei | CMGC/DYRK protein kinase, putative | 0.0095 | 0.4291 | 0.9151 |
Schistosoma mansoni | aldo-keto reductase | 0.0101 | 0.4632 | 0.4555 |
Brugia malayi | Tyrosine-protein kinase abl-1 | 0.0039 | 0.1143 | 0.1372 |
Brugia malayi | acetyltransferase, GNAT family protein | 0.0155 | 0.761 | 0.9352 |
Loa Loa (eye worm) | TK protein kinase | 0.0036 | 0.0973 | 0.1012 |
Echinococcus multilocularis | c src tyrosine kinase | 0.0039 | 0.1143 | 0.0993 |
Entamoeba histolytica | alcohol dehydrogenase, putative | 0.0029 | 0.0611 | 0.1319 |
Echinococcus multilocularis | aldehyde dehydrogenase, mitochondrial | 0.0067 | 0.2709 | 0.2585 |
Echinococcus granulosus | aldo keto reductase | 0.0101 | 0.4632 | 0.4542 |
Echinococcus multilocularis | tyrosine protein kinase Fyn | 0.0071 | 0.295 | 0.2831 |
Loa Loa (eye worm) | oxidoreductase | 0.0101 | 0.4632 | 0.5604 |
Loa Loa (eye worm) | hypothetical protein | 0.0095 | 0.4263 | 0.5141 |
Mycobacterium ulcerans | aldehyde dehydrogenase | 0.0067 | 0.2709 | 0.5216 |
Echinococcus multilocularis | NCK adaptor protein | 0.0035 | 0.0949 | 0.0796 |
Echinococcus multilocularis | tyrosine protein kinase Blk | 0.0054 | 0.1974 | 0.1838 |
Echinococcus granulosus | lysine specific demethylase 5A | 0.0065 | 0.2591 | 0.2466 |
Schistosoma mansoni | proto-oncogene tyrosine-protein kinase src | 0.0039 | 0.1143 | 0.1015 |
Echinococcus granulosus | tyrosine kinase|tyrosine protein kinase Fyn | 0.0054 | 0.1974 | 0.1838 |
Echinococcus multilocularis | aldo keto reductase family 1, member B4 | 0.0101 | 0.4632 | 0.4542 |
Loa Loa (eye worm) | GTP-binding regulatory protein Gs alpha-S chain | 0.0099 | 0.4501 | 0.544 |
Toxoplasma gondii | histone lysine acetyltransferase GCN5-B | 0.0046 | 0.1512 | 0.2305 |
Toxoplasma gondii | aldo/keto reductase family oxidoreductase | 0.0029 | 0.0611 | 0.0084 |
Echinococcus multilocularis | tyrosine protein kinase HCK | 0.0036 | 0.0973 | 0.082 |
Trypanosoma cruzi | aldo-keto reductase | 0.0101 | 0.4632 | 1 |
Trypanosoma cruzi | CMGC/DYRK protein kinase, putative | 0.0095 | 0.4291 | 0.9151 |
Echinococcus granulosus | aldo keto reductase family 1 member B4 | 0.0101 | 0.4632 | 0.4542 |
Brugia malayi | SRC-1 | 0.0071 | 0.295 | 0.3602 |
Echinococcus granulosus | aldo keto reductase family 1 member B4 | 0.0101 | 0.4632 | 0.4542 |
Echinococcus multilocularis | aldo keto reductase family 1, member B4 | 0.0101 | 0.4632 | 0.4542 |
Entamoeba histolytica | alcohol dehydrogenase, putative | 0.0029 | 0.0611 | 0.1319 |
Plasmodium falciparum | ATP-dependent Clp protease proteolytic subunit | 0.0084 | 0.3632 | 1 |
Schistosoma mansoni | hypothetical protein | 0.0198 | 1 | 1 |
Mycobacterium ulcerans | ATP-dependent Clp protease proteolytic subunit | 0.0084 | 0.3632 | 0.7513 |
Echinococcus multilocularis | tyrosine protein kinase Fyn | 0.0054 | 0.1974 | 0.1838 |
Loa Loa (eye worm) | hypothetical protein | 0.0101 | 0.4632 | 0.5604 |
Schistosoma mansoni | jumonji domain containing protein | 0.0065 | 0.2591 | 0.2485 |
Trichomonas vaginalis | dihydrodiol dehydrogenase, putative | 0.0101 | 0.4632 | 1 |
Trichomonas vaginalis | aldo-keto reductase, putative | 0.0101 | 0.4632 | 1 |
Echinococcus granulosus | NCK adaptor protein | 0.0035 | 0.0949 | 0.0796 |
Leishmania major | prostaglandin f synthase, putative | 0.0101 | 0.4632 | 1 |
Trypanosoma cruzi | PAB1-binding protein , putative | 0.0029 | 0.0612 | 0.0002 |
Echinococcus multilocularis | dual specificity | 0.0095 | 0.4291 | 0.4194 |
Echinococcus multilocularis | Transcription factor, JmjC domain containing protein | 0.0065 | 0.2591 | 0.2466 |
Loa Loa (eye worm) | hypothetical protein | 0.0035 | 0.0949 | 0.0982 |
Echinococcus multilocularis | tyrosine protein kinase Fgr | 0.0071 | 0.295 | 0.2831 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0099 | 0.4501 | 0.4423 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0099 | 0.4501 | 0.4423 |
Onchocerca volvulus | 0.0101 | 0.4632 | 1 | |
Brugia malayi | GTP-binding regulatory protein Gs alpha-S chain, putative | 0.0099 | 0.4501 | 0.5516 |
Trypanosoma brucei | PAB1-binding protein , putative | 0.0029 | 0.0612 | 0.0002 |
Echinococcus multilocularis | lysine specific demethylase 5A | 0.0065 | 0.2591 | 0.2466 |
Echinococcus multilocularis | tyrosine protein kinase Btk29A | 0.0039 | 0.1143 | 0.0993 |
Mycobacterium leprae | PROBABLE ATP-DEPENDENT CLP PROTEASE PROTEOLYTIC SUBUNIT 1 CLPP1 (ENDOPEPTIDASE CLP) | 0.0055 | 0.2027 | 0.3574 |
Trichomonas vaginalis | aldo-keto reductase, putative | 0.0101 | 0.4632 | 1 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0099 | 0.4501 | 0.4408 |
Plasmodium vivax | ATP-dependent Clp protease proteolytic subunit, putative | 0.0084 | 0.3632 | 1 |
Entamoeba histolytica | aldose reductase, putative | 0.0101 | 0.4632 | 1 |
Entamoeba histolytica | SH2-protein kinase domain containing protein | 0.0021 | 0.0166 | 0.0359 |
Schistosoma mansoni | nck2/grb4 | 0.0035 | 0.0949 | 0.0819 |
Onchocerca volvulus | 0.0101 | 0.4632 | 1 | |
Echinococcus multilocularis | aldo keto reductase | 0.0101 | 0.4632 | 0.4542 |
Toxoplasma gondii | ATP-dependent Clp endopeptidase, proteolytic subunit ClpP domain-containing protein | 0.0084 | 0.3632 | 0.7534 |
Echinococcus granulosus | tyrosine protein kinase Src42A | 0.005 | 0.178 | 0.1641 |
Chlamydia trachomatis | ATP-dependent Clp protease proteolytic subunit | 0.0084 | 0.3632 | 0.5 |
Brugia malayi | Protein kinase domain containing protein | 0.0095 | 0.4291 | 0.5256 |
Plasmodium falciparum | aldehyde reductase, putative | 0.0029 | 0.0611 | 0.0111 |
Schistosoma mansoni | tyrosine kinase | 0.0039 | 0.1143 | 0.1015 |
Giardia lamblia | Aldose reductase | 0.0101 | 0.4632 | 1 |
Brugia malayi | protein-tyrosine kinase | 0.0054 | 0.1974 | 0.2397 |
Trichomonas vaginalis | aldo-keto reductase, putative | 0.0101 | 0.4632 | 1 |
Trichomonas vaginalis | bromodomain-containing protein, putative | 0.0046 | 0.1512 | 0.224 |
Leishmania major | prostaglandin f2-alpha synthase/D-arabinose dehydrogenase | 0.0101 | 0.4632 | 1 |
Echinococcus granulosus | voltage gated potassium channel subunit | 0.0029 | 0.0611 | 0.0452 |
Echinococcus multilocularis | aldo keto reductase family 1, member B4 | 0.0101 | 0.4632 | 0.4542 |
Onchocerca volvulus | 0.0101 | 0.4632 | 1 | |
Trichomonas vaginalis | dihydrodiol dehydrogenase, putative | 0.0101 | 0.4632 | 1 |
Echinococcus multilocularis | tyrosine protein kinase Src42A | 0.0071 | 0.295 | 0.2831 |
Schistosoma mansoni | adapter molecule crk | 0.0035 | 0.0949 | 0.0819 |
Echinococcus multilocularis | tyrosine protein kinase Fyn | 0.0071 | 0.295 | 0.2831 |
Plasmodium vivax | ataxin-2 like protein, putative | 0.0029 | 0.0612 | 0.0113 |
Echinococcus granulosus | aldo keto reductase family 1 member B4 | 0.0101 | 0.4632 | 0.4542 |
Brugia malayi | Variant SH3 domain containing protein | 0.0035 | 0.0949 | 0.1133 |
Echinococcus multilocularis | aldo keto reductase | 0.0101 | 0.4632 | 0.4542 |
Brugia malayi | SH2 domain containing protein | 0.0021 | 0.0166 | 0.0167 |
Mycobacterium ulcerans | aldehyde dehydrogenase | 0.0067 | 0.2709 | 0.5216 |
Schistosoma mansoni | potassium channel beta | 0.0029 | 0.0611 | 0.0476 |
Loa Loa (eye worm) | sex muscle abnormal protein 5 | 0.0164 | 0.8136 | 1 |
Brugia malayi | Sex muscle abnormal protein 5 | 0.0164 | 0.8136 | 1 |
Echinococcus granulosus | histone acetyltransferase KAT2B | 0.0046 | 0.1512 | 0.1368 |
Entamoeba histolytica | protein kinase, putative | 0.0095 | 0.4291 | 0.9263 |
Toxoplasma gondii | ATP-dependent Clp endopeptidase, proteolytic subunit ClpP domain-containing protein | 0.0084 | 0.3632 | 0.7534 |
Brugia malayi | Protein kinase domain containing protein | 0.0021 | 0.0166 | 0.0167 |
Trypanosoma brucei | prostaglandin f synthase | 0.0101 | 0.4632 | 1 |
Echinococcus multilocularis | aldo keto reductase family 1, member B4 | 0.0101 | 0.4632 | 0.4542 |
Echinococcus granulosus | tyrosine protein kinase HCK | 0.0036 | 0.0973 | 0.082 |
Echinococcus multilocularis | voltage gated potassium channel subunit | 0.0029 | 0.0611 | 0.0452 |
Plasmodium falciparum | aldo-keto reductase, putative | 0.0029 | 0.0611 | 0.0111 |
Loa Loa (eye worm) | oxidoreductase | 0.0101 | 0.4632 | 0.5604 |
Brugia malayi | jmjC domain containing protein | 0.0065 | 0.2591 | 0.3159 |
Schistosoma mansoni | tyrosine kinase | 0.0071 | 0.295 | 0.2849 |
Toxoplasma gondii | histone lysine acetyltransferase GCN5-A | 0.0046 | 0.1512 | 0.2305 |
Brugia malayi | Probable ClpP-like protease | 0.0084 | 0.3632 | 0.4444 |
Mycobacterium leprae | PROBABLE ATP-DEPENDENT CLP PROTEASE PROTEOLYTIC SUBUNIT 2 CLPP2 (ENDOPEPTIDASE CLP 2) | 0.0084 | 0.3632 | 0.7534 |
Toxoplasma gondii | LsmAD domain-containing protein | 0.0029 | 0.0612 | 0.0086 |
Trypanosoma cruzi | CMGC/DYRK protein kinase, putative | 0.0095 | 0.4291 | 0.9151 |
Echinococcus multilocularis | aldo keto reductase family 1, member B4 | 0.0101 | 0.4632 | 0.4542 |
Echinococcus granulosus | proto oncogene tyrosine protein kinase LCK | 0.0071 | 0.295 | 0.2831 |
Brugia malayi | Protein kinase domain containing protein | 0.0021 | 0.0166 | 0.0167 |
Echinococcus multilocularis | aldehyde reductase | 0.0072 | 0.2993 | 0.2874 |
Trichomonas vaginalis | aldo-keto reductase, putative | 0.0101 | 0.4632 | 1 |
Echinococcus granulosus | c src tyrosine kinase | 0.0039 | 0.1143 | 0.0993 |
Echinococcus multilocularis | tyrosine protein kinase Srms | 0.0054 | 0.1974 | 0.1838 |
Schistosoma mansoni | tyrosine kinase | 0.0039 | 0.1143 | 0.1015 |
Entamoeba histolytica | protein kinase, putative | 0.0036 | 0.0973 | 0.2099 |
Entamoeba histolytica | acetyltransferase, GNAT family | 0.0042 | 0.13 | 0.2807 |
Toxoplasma gondii | aldehyde dehydrogenase | 0.0067 | 0.2709 | 0.5256 |
Schistosoma mansoni | tyrosine kinase | 0.0071 | 0.295 | 0.2849 |
Echinococcus multilocularis | aldo keto reductase family 1, member B4 | 0.0101 | 0.4632 | 0.4542 |
Echinococcus multilocularis | aldo keto reductase family 1, member B4 | 0.0101 | 0.4632 | 0.4542 |
Brugia malayi | Protein kinase domain containing protein | 0.0021 | 0.0166 | 0.0167 |
Echinococcus granulosus | aldo keto reductase family 1 member B4 | 0.0101 | 0.4632 | 0.4542 |
Onchocerca volvulus | 0.0101 | 0.4632 | 1 | |
Echinococcus granulosus | aldo keto reductase family 1 member B4 | 0.0101 | 0.4632 | 0.4542 |
Echinococcus granulosus | tyrosine protein kinase Src64B | 0.0071 | 0.295 | 0.2831 |
Loa Loa (eye worm) | CMGC/DYRK/DYRK1 protein kinase | 0.0095 | 0.4291 | 0.5176 |
Schistosoma mansoni | peptidase Clp (S14 family) | 0.0084 | 0.3632 | 0.3541 |
Plasmodium vivax | aldehyde reductase, putative | 0.0029 | 0.0611 | 0.0111 |
Echinococcus granulosus | tyrosine protein kinase Src42A | 0.0071 | 0.295 | 0.2831 |
Schistosoma mansoni | proto-oncogene tyrosine-protein kinase abl1 | 0.0035 | 0.0949 | 0.0819 |
Entamoeba histolytica | aldose reductase, putative | 0.0101 | 0.4632 | 1 |
Loa Loa (eye worm) | jmjC domain-containing protein | 0.0065 | 0.2591 | 0.3043 |
Echinococcus granulosus | tyrosine protein kinase Fyn | 0.0071 | 0.295 | 0.2831 |
Loa Loa (eye worm) | hypothetical protein | 0.0029 | 0.0612 | 0.0559 |
Echinococcus multilocularis | peptidase Clp (S14 family) | 0.0055 | 0.2027 | 0.1892 |
Loa Loa (eye worm) | oxidoreductase | 0.0101 | 0.4632 | 0.5604 |
Mycobacterium ulcerans | oxidoreductase | 0.0101 | 0.4632 | 1 |
Echinococcus granulosus | Transcription factor JmjC domain containing protein | 0.0065 | 0.2591 | 0.2466 |
Trichomonas vaginalis | aldo-keto reductase, putative | 0.0101 | 0.4632 | 1 |
Mycobacterium tuberculosis | Probable oxidoreductase | 0.0101 | 0.4632 | 1 |
Echinococcus multilocularis | aldo keto reductase | 0.0101 | 0.4632 | 0.4542 |
Echinococcus granulosus | tyrosine protein kinase Blk | 0.0054 | 0.1974 | 0.1838 |
Mycobacterium ulcerans | aldehyde dehydrogenase | 0.0067 | 0.2709 | 0.5216 |
Toxoplasma gondii | aldo-keto reductase | 0.0029 | 0.0611 | 0.0084 |
Brugia malayi | Protein kinase domain containing protein | 0.0021 | 0.0166 | 0.0167 |
Brugia malayi | NADH-dependent xylose reductase | 0.0029 | 0.0611 | 0.0716 |
Echinococcus multilocularis | tyrosine protein kinase Fyn | 0.0071 | 0.295 | 0.2831 |
Leishmania major | aldo-keto reductase-like protein | 0.0101 | 0.4632 | 1 |
Echinococcus granulosus | 3'partial|tyrosine protein kinase Fgr | 0.0071 | 0.295 | 0.2831 |
Mycobacterium ulcerans | ATP-dependent Clp protease proteolytic subunit | 0.0084 | 0.3632 | 0.7513 |
Activity type | Activity value | Assay description | Source | Reference |
---|---|---|---|---|
Potency (functional) | 22.3872 uM | PUBCHEM_BIOASSAY: qHTS Assay for Inhibitors of the Phosphatase Activity of Eya2. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID488939] | ChEMBL. | No reference |
Potency (functional) | = 31.6228 um | PUBCHEM_BIOASSAY: qHTS Inhibitors of AmpC Beta-Lactamase (assay with detergent). (Class of assay: confirmatory) [Related pubchem assays: 1002 (Confirmation Concentration-Response Assay for Inhibitors of AmpC Beta-Lactamase (assay with detergent)), 585 (Promiscuous and Specific Inhibitors of AmpC Beta-Lactamase (assay without detergent) - a screen old NIH MLSMR collection), 584 (Promiscuous and Specific Inhibitors of AmpC Beta-Lactamase (assay with detergent) - a screen of the old NIH MLSMR collection), 1003 (Confirmation Cuvette-Based Assay for Inhibitors of AmpC Beta-Lactamase (assay with detergent))] | ChEMBL. | No reference |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.