Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Schistosoma mansoni | Smad4 | 0.0008 | 0.0066 | 0.0066 |
Schistosoma mansoni | tar DNA-binding protein | 0.013 | 0.2968 | 0.2968 |
Loa Loa (eye worm) | hypothetical protein | 0.0013 | 0.0167 | 0.0465 |
Brugia malayi | TAR-binding protein | 0.013 | 0.2968 | 0.827 |
Echinococcus granulosus | SAM and MBT domain containing protein | 0.005 | 0.1047 | 0.1047 |
Schistosoma mansoni | cpg binding protein | 0.003 | 0.0576 | 0.0576 |
Brugia malayi | mbt repeat family protein | 0.005 | 0.1047 | 0.2917 |
Echinococcus multilocularis | GPCR, family 2 | 0.005 | 0.1043 | 0.1043 |
Echinococcus granulosus | diuretic hormone 44 receptor GPRdih2 | 0.005 | 0.1043 | 0.1043 |
Loa Loa (eye worm) | hypothetical protein | 0.005 | 0.1043 | 0.2906 |
Schistosoma mansoni | sex comb on midleg homolog | 0.005 | 0.1047 | 0.1047 |
Brugia malayi | Nuclear hormone receptor family member nhr-25 | 0.0011 | 0.0121 | 0.0337 |
Schistosoma mansoni | DNA polymerase eta | 0.0095 | 0.2122 | 0.2122 |
Schistosoma mansoni | RAR-like nuclear receptor | 0.0011 | 0.0121 | 0.0121 |
Onchocerca volvulus | 0.003 | 0.0576 | 0.4921 | |
Echinococcus granulosus | endonuclease exonuclease phosphatase | 0.0196 | 0.4522 | 0.4522 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0041 | 0.0838 | 0.3432 |
Echinococcus multilocularis | ecdysone induced protein 78C | 0.0011 | 0.0121 | 0.0121 |
Toxoplasma gondii | aldehyde dehydrogenase | 0.0063 | 0.1358 | 0.9274 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.005 | 0.1046 | 0.1046 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-14 | 0.0011 | 0.0121 | 0.0337 |
Schistosoma mansoni | rab geranylgeranyl transferase alpha subunit | 0.0041 | 0.0838 | 0.0838 |
Schistosoma mansoni | terminal deoxycytidyl transferase | 0.0041 | 0.0838 | 0.0838 |
Schistosoma mansoni | smad | 0.0008 | 0.0066 | 0.0066 |
Echinococcus granulosus | GPCR family 2 | 0.005 | 0.1043 | 0.1043 |
Echinococcus granulosus | retinoic acid receptor rxr beta a | 0.0011 | 0.0121 | 0.0121 |
Trypanosoma brucei | tyrosyl-DNA Phosphodiesterase (Tdp1), putative | 0.0072 | 0.157 | 0.7175 |
Echinococcus multilocularis | transcription factor Dp 1 | 0.0041 | 0.0852 | 0.0852 |
Echinococcus multilocularis | smad | 0.0008 | 0.0066 | 0.0066 |
Loa Loa (eye worm) | hypothetical protein | 0.0095 | 0.2122 | 0.5913 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0041 | 0.0838 | 0.3432 |
Echinococcus granulosus | TGF beta signal transducer SmadC | 0.0008 | 0.0066 | 0.0066 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0028 | 0.0536 | 0.1887 |
Mycobacterium ulcerans | DNA polymerase IV | 0.0041 | 0.0838 | 0.5633 |
Brugia malayi | MH2 domain containing protein | 0.0124 | 0.2812 | 0.7835 |
Echinococcus multilocularis | terminal deoxycytidyl transferase rev1 | 0.0041 | 0.0838 | 0.0838 |
Schistosoma mansoni | steroid hormone receptor ad4bp | 0.0011 | 0.0121 | 0.0121 |
Trypanosoma cruzi | DNA polymerase kappa, putative | 0.0041 | 0.0838 | 0.3432 |
Brugia malayi | polk-prov protein | 0.0013 | 0.0167 | 0.0465 |
Leishmania major | aldehyde dehydrogenase, mitochondrial precursor | 0.0063 | 0.1358 | 0.6092 |
Loa Loa (eye worm) | mbt repeat family protein | 0.005 | 0.1047 | 0.2917 |
Echinococcus multilocularis | cadherin EGF LAG seven pass G type receptor | 0.005 | 0.1043 | 0.1043 |
Echinococcus multilocularis | Nuclear hormone receptor family member nhr 41 | 0.0011 | 0.0121 | 0.0121 |
Echinococcus multilocularis | thyroid hormone receptor alpha | 0.0011 | 0.0121 | 0.0121 |
Loa Loa (eye worm) | hypothetical protein | 0.0011 | 0.0121 | 0.0337 |
Schistosoma mansoni | hypothetical protein | 0.0426 | 1 | 1 |
Trypanosoma cruzi | DNA polymerase kappa, putative | 0.0041 | 0.0838 | 0.3432 |
Trypanosoma cruzi | tyrosyl-DNA Phosphodiesterase (Tdp1), putative | 0.0072 | 0.157 | 0.7175 |
Brugia malayi | Ligand-binding domain of nuclear hormone receptor family protein | 0.0011 | 0.0121 | 0.0337 |
Loa Loa (eye worm) | hypothetical protein | 0.0011 | 0.0121 | 0.0337 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.005 | 0.1046 | 0.1046 |
Loa Loa (eye worm) | GTP-binding regulatory protein Gs alpha-S chain | 0.005 | 0.1046 | 0.2915 |
Echinococcus multilocularis | SAM and MBT domain containing protein | 0.005 | 0.1047 | 0.1047 |
Echinococcus multilocularis | tyrosyl DNA phosphodiesterase 1 | 0.0072 | 0.157 | 0.157 |
Brugia malayi | F/Y-rich N-terminus family protein | 0.0009 | 0.0082 | 0.0229 |
Schistosoma mansoni | TGF-beta signal transducer Smad2 | 0.0008 | 0.0066 | 0.0066 |
Brugia malayi | RNA recognition motif domain containing protein | 0.013 | 0.2968 | 0.827 |
Trypanosoma cruzi | DNA polymerase eta, putative | 0.0095 | 0.2122 | 1 |
Echinococcus granulosus | FTZ F1 nuclear receptor protein | 0.0011 | 0.0121 | 0.0121 |
Echinococcus granulosus | suppression of tumorigenicity 18 protein | 0.0057 | 0.121 | 0.121 |
Loa Loa (eye worm) | MH2 domain-containing protein | 0.0124 | 0.2812 | 0.7835 |
Loa Loa (eye worm) | RNA binding protein | 0.013 | 0.2968 | 0.827 |
Schistosoma mansoni | DNA polymerase IV / kappa | 0.0013 | 0.0167 | 0.0167 |
Mycobacterium ulcerans | DNA polymerase IV | 0.0041 | 0.0838 | 0.5633 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.005 | 0.1046 | 0.1046 |
Brugia malayi | Nuclear hormone receptor family member nhr-25 | 0.0011 | 0.0121 | 0.0337 |
Brugia malayi | MH1 domain containing protein | 0.0008 | 0.0066 | 0.0183 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.005 | 0.1046 | 0.1046 |
Brugia malayi | CXXC zinc finger family protein | 0.003 | 0.0576 | 0.1606 |
Loa Loa (eye worm) | hypothetical protein | 0.0057 | 0.121 | 0.3372 |
Loa Loa (eye worm) | histone methyltransferase | 0.0009 | 0.0085 | 0.0237 |
Schistosoma mansoni | hypothetical protein | 0.005 | 0.1043 | 0.1043 |
Schistosoma mansoni | tar DNA-binding protein | 0.013 | 0.2968 | 0.2968 |
Trypanosoma brucei | DNA polymerase IV, putative | 0.0041 | 0.0838 | 0.3432 |
Echinococcus multilocularis | COUP TF:Svp nuclear hormone receptor | 0.0011 | 0.0121 | 0.0121 |
Schistosoma mansoni | hypothetical protein | 0.0302 | 0.705 | 0.705 |
Brugia malayi | MH2 domain containing protein | 0.0008 | 0.0066 | 0.0183 |
Echinococcus multilocularis | endonuclease exonuclease phosphatase | 0.0196 | 0.4522 | 0.4522 |
Schistosoma mansoni | retinoid-x-receptor (RXR) | 0.0011 | 0.0121 | 0.0121 |
Schistosoma mansoni | Tr4/Tr2 (homologue) | 0.0011 | 0.0121 | 0.0121 |
Brugia malayi | MH2 domain containing protein | 0.0008 | 0.0066 | 0.0183 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.005 | 0.1046 | 0.1046 |
Loa Loa (eye worm) | latrophilin receptor protein 2 | 0.005 | 0.1043 | 0.2906 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.005 | 0.1046 | 0.1046 |
Loa Loa (eye worm) | MH2 domain-containing protein | 0.0008 | 0.0066 | 0.0183 |
Schistosoma mansoni | hypothetical protein | 0.005 | 0.1043 | 0.1043 |
Brugia malayi | Corticotropin releasing factor receptor 2 precursor, putative | 0.0157 | 0.3589 | 1 |
Echinococcus granulosus | histone lysine N methyltransferase MLL3 | 0.0007 | 0.0042 | 0.0042 |
Echinococcus granulosus | cpg binding protein | 0.0032 | 0.0617 | 0.0617 |
Echinococcus multilocularis | nuclear receptor 2DBD gamma | 0.0011 | 0.0121 | 0.0121 |
Loa Loa (eye worm) | transcription factor SMAD2 | 0.0124 | 0.2812 | 0.7835 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0041 | 0.0838 | 0.3432 |
Entamoeba histolytica | tyrosyl-DNA phosphodiesterase, putative | 0.0072 | 0.157 | 1 |
Echinococcus multilocularis | mothers against decapentaplegic 5 | 0.0008 | 0.0066 | 0.0066 |
Toxoplasma gondii | histone lysine methyltransferase SET1 | 0.0057 | 0.1213 | 0.8146 |
Schistosoma mansoni | sex comb on midleg homolog | 0.005 | 0.1047 | 0.1047 |
Schistosoma mansoni | nuclear hormone receptor nor-1/nor-2 | 0.0011 | 0.0121 | 0.0121 |
Echinococcus granulosus | aldehyde dehydrogenase mitochondrial | 0.0063 | 0.1358 | 0.1358 |
Brugia malayi | Smad1 | 0.0008 | 0.0066 | 0.0183 |
Brugia malayi | ImpB/MucB/SamB family protein | 0.0095 | 0.2122 | 0.5913 |
Echinococcus multilocularis | histone acetyltransferase MYST2 | 0.0057 | 0.121 | 0.121 |
Plasmodium vivax | DNA repair protein REV1, putative | 0.0013 | 0.0167 | 0.5 |
Echinococcus granulosus | dna polymerase eta | 0.0095 | 0.2122 | 0.2122 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0028 | 0.0536 | 0.1887 |
Schistosoma mansoni | nuclear receptor 2DBD-gamma | 0.0011 | 0.0121 | 0.0121 |
Brugia malayi | Nuclear hormone receptor family member nhr-19 | 0.0011 | 0.0121 | 0.0337 |
Schistosoma mansoni | smad1 5 8 and | 0.0008 | 0.0066 | 0.0066 |
Loa Loa (eye worm) | hypothetical protein | 0.0157 | 0.3589 | 1 |
Brugia malayi | Nuclear hormone receptor family member nhr-14 | 0.0011 | 0.0121 | 0.0337 |
Echinococcus multilocularis | geminin | 0.0357 | 0.8356 | 0.8356 |
Trypanosoma cruzi | tyrosyl-DNA Phosphodiesterase (Tdp1), putative | 0.0072 | 0.157 | 0.7175 |
Giardia lamblia | DINP protein human, muc B family | 0.0041 | 0.0838 | 1 |
Leishmania major | DNA polymerase eta, putative | 0.0095 | 0.2122 | 1 |
Echinococcus granulosus | hepatocyte nuclear factor 4 alpha | 0.0011 | 0.0121 | 0.0121 |
Trypanosoma cruzi | DNA polymerase kappa, putative | 0.0041 | 0.0838 | 0.3432 |
Schistosoma mansoni | myelin transcription factor 1 myt1 | 0.0057 | 0.121 | 0.121 |
Brugia malayi | RNA binding protein | 0.013 | 0.2968 | 0.827 |
Loa Loa (eye worm) | pigment dispersing factor receptor c | 0.0157 | 0.3589 | 1 |
Brugia malayi | STAT protein, DNA binding domain containing protein | 0.0137 | 0.3124 | 0.8704 |
Brugia malayi | Calcitonin receptor-like protein seb-1 | 0.0157 | 0.3589 | 1 |
Echinococcus multilocularis | tar DNA binding protein | 0.013 | 0.2968 | 0.2968 |
Schistosoma mansoni | hypothetical protein | 0.005 | 0.1043 | 0.1043 |
Schistosoma mansoni | hypothetical protein | 0.0357 | 0.8356 | 0.8356 |
Echinococcus granulosus | cadherin EGF LAG seven pass G type receptor | 0.005 | 0.1043 | 0.1043 |
Echinococcus multilocularis | TGF beta signal transducer SmadC | 0.0008 | 0.0066 | 0.0066 |
Schistosoma mansoni | mixed-lineage leukemia protein mll | 0.0063 | 0.1374 | 0.1374 |
Loa Loa (eye worm) | MBCTL1 | 0.0057 | 0.121 | 0.3372 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-40 | 0.0011 | 0.0121 | 0.0337 |
Loa Loa (eye worm) | ImpB/MucB/SamB family protein | 0.0041 | 0.0838 | 0.2334 |
Brugia malayi | Nuclear hormone receptor family member nhr-49 | 0.0011 | 0.0121 | 0.0337 |
Echinococcus multilocularis | suppression of tumorigenicity 18 protein | 0.0057 | 0.121 | 0.121 |
Echinococcus multilocularis | dnaJ subfamily B | 0.0426 | 1 | 1 |
Brugia malayi | Tyrosyl-DNA phosphodiesterase family protein | 0.0072 | 0.157 | 0.4374 |
Echinococcus granulosus | smad | 0.0008 | 0.0066 | 0.0066 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0041 | 0.0838 | 0.3432 |
Trichomonas vaginalis | DNA polymerase IV / kappa, putative | 0.0041 | 0.0838 | 1 |
Echinococcus multilocularis | dna polymerase eta | 0.0095 | 0.2122 | 0.2122 |
Trypanosoma brucei | unspecified product | 0.0041 | 0.0838 | 0.3432 |
Echinococcus granulosus | FTZ F1 alpha | 0.0011 | 0.0121 | 0.0121 |
Brugia malayi | Latrophilin receptor protein 2 | 0.005 | 0.1043 | 0.2906 |
Loa Loa (eye worm) | hypothetical protein | 0.0011 | 0.0121 | 0.0337 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0041 | 0.0838 | 0.3432 |
Echinococcus granulosus | mothers against decapentaplegic 5 | 0.0008 | 0.0066 | 0.0066 |
Echinococcus granulosus | Nuclear hormone receptor family member nhr 41 | 0.0011 | 0.0121 | 0.0121 |
Brugia malayi | GTP-binding regulatory protein Gs alpha-S chain, putative | 0.005 | 0.1046 | 0.2915 |
Brugia malayi | Nuclear hormone receptor family member nhr-40 | 0.0011 | 0.0121 | 0.0337 |
Brugia malayi | Nuclear hormone receptor family member nhr-3 | 0.0011 | 0.0121 | 0.0337 |
Brugia malayi | Nuclear hormone receptor family member nhr-19 | 0.0011 | 0.0121 | 0.0337 |
Loa Loa (eye worm) | steroid hormone receptor | 0.0011 | 0.0121 | 0.0337 |
Loa Loa (eye worm) | hypothetical protein | 0.0011 | 0.0121 | 0.0337 |
Trichomonas vaginalis | DNA polymerase eta, putative | 0.0041 | 0.0838 | 1 |
Echinococcus granulosus | nuclear receptor 2DBD gamma | 0.0011 | 0.0121 | 0.0121 |
Echinococcus granulosus | terminal deoxycytidyl transferase rev1 | 0.0041 | 0.0838 | 0.0838 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.005 | 0.1046 | 0.1046 |
Brugia malayi | latrophilin 2 splice variant baaae | 0.0107 | 0.241 | 0.6717 |
Schistosoma mansoni | retinoic acid receptor RXR | 0.0011 | 0.0121 | 0.0121 |
Brugia malayi | steroid hormone receptor | 0.0011 | 0.0121 | 0.0337 |
Schistosoma mansoni | smad1 5 8 and | 0.0008 | 0.0066 | 0.0066 |
Brugia malayi | calcium-independent alpha-latrotoxin receptor 2, putative | 0.005 | 0.1043 | 0.2906 |
Trypanosoma cruzi | DNA polymerase eta, putative | 0.0067 | 0.1451 | 0.6568 |
Mycobacterium ulcerans | aldehyde dehydrogenase | 0.0063 | 0.1358 | 1 |
Loa Loa (eye worm) | tyrosyl-DNA phosphodiesterase | 0.0072 | 0.157 | 0.4374 |
Schistosoma mansoni | coup transcription factor | 0.0011 | 0.0121 | 0.0121 |
Echinococcus granulosus | tar DNA binding protein | 0.013 | 0.2968 | 0.2968 |
Brugia malayi | Nuclear hormone receptor-like 1 | 0.0011 | 0.0121 | 0.0337 |
Onchocerca volvulus | Polycomb protein Sfmbt homolog | 0.005 | 0.1047 | 1 |
Loa Loa (eye worm) | STAT protein | 0.0137 | 0.3124 | 0.8704 |
Schistosoma mansoni | nuclear hormone receptor | 0.0011 | 0.0121 | 0.0121 |
Brugia malayi | nuclear receptor NHR-88 | 0.0011 | 0.0121 | 0.0337 |
Loa Loa (eye worm) | MH1 domain-containing protein | 0.0008 | 0.0066 | 0.0183 |
Schistosoma mansoni | FTZ-F1 nuclear receptor-like protein | 0.0011 | 0.0121 | 0.0121 |
Leishmania major | DNA polymerase kappa, putative | 0.0041 | 0.0838 | 0.3432 |
Schistosoma mansoni | scm-relatedprotein containing 4 mbt domains (sfmbt) | 0.005 | 0.1047 | 0.1047 |
Leishmania major | DNA polymerase kappa, putative,DNA polymerase IV, putative | 0.0041 | 0.0838 | 0.3432 |
Trypanosoma brucei | DNA polymerase IV, putative | 0.0041 | 0.0838 | 0.3432 |
Mycobacterium ulcerans | aldehyde dehydrogenase | 0.0063 | 0.1358 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0011 | 0.0121 | 0.0337 |
Leishmania major | tyrosyl-DNA phosphodiesterase 1 | 0.0072 | 0.157 | 0.7175 |
Echinococcus granulosus | Smad4 | 0.0008 | 0.0066 | 0.0066 |
Loa Loa (eye worm) | nuclear Hormone Receptor family member | 0.0011 | 0.0121 | 0.0337 |
Echinococcus multilocularis | histone lysine N methyltransferase MLL3 | 0.0009 | 0.0085 | 0.0085 |
Brugia malayi | ImpB/MucB/SamB family protein | 0.0041 | 0.0838 | 0.2334 |
Schistosoma mansoni | hypothetical protein | 0.0107 | 0.241 | 0.241 |
Echinococcus granulosus | ecdysone induced protein 78C | 0.0011 | 0.0121 | 0.0121 |
Trypanosoma brucei | DNA polymerase IV, putative | 0.0041 | 0.0838 | 0.3432 |
Schistosoma mansoni | tar DNA-binding protein | 0.013 | 0.2968 | 0.2968 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-31 | 0.0011 | 0.0121 | 0.0337 |
Brugia malayi | nuclear hormone receptor | 0.0011 | 0.0121 | 0.0337 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-41 | 0.0011 | 0.0121 | 0.0337 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-49 | 0.0011 | 0.0121 | 0.0337 |
Onchocerca volvulus | 0.005 | 0.1047 | 1 | |
Brugia malayi | mbt repeat family protein | 0.005 | 0.1047 | 0.2917 |
Echinococcus multilocularis | aldehyde dehydrogenase, mitochondrial | 0.0063 | 0.1358 | 0.1358 |
Loa Loa (eye worm) | hypothetical protein | 0.0011 | 0.0121 | 0.0337 |
Schistosoma mansoni | mixed-lineage leukemia protein mll | 0.0007 | 0.0042 | 0.0042 |
Echinococcus multilocularis | dna polymerase kappa | 0.0041 | 0.0838 | 0.0838 |
Loa Loa (eye worm) | TAR-binding protein | 0.013 | 0.2968 | 0.827 |
Echinococcus granulosus | tyrosyl DNA phosphodiesterase 1 | 0.0072 | 0.157 | 0.157 |
Echinococcus multilocularis | polycomb protein SCMH1 | 0.005 | 0.1047 | 0.1047 |
Schistosoma mansoni | tar DNA-binding protein | 0.013 | 0.2968 | 0.2968 |
Loa Loa (eye worm) | CXXC zinc finger family protein | 0.003 | 0.0576 | 0.1606 |
Echinococcus multilocularis | histone lysine N methyltransferase MLL3 | 0.0007 | 0.0042 | 0.0042 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0041 | 0.0838 | 0.3432 |
Echinococcus granulosus | dna polymerase kappa | 0.0041 | 0.0838 | 0.0838 |
Mycobacterium tuberculosis | Probable aldehyde dehydrogenase | 0.0063 | 0.1358 | 1 |
Echinococcus multilocularis | Smad4 | 0.0008 | 0.0066 | 0.0066 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0041 | 0.0838 | 0.3432 |
Echinococcus granulosus | transcription factor Dp 1 | 0.0041 | 0.0852 | 0.0852 |
Brugia malayi | Nuclear hormone receptor family member nhr-1 | 0.0011 | 0.0121 | 0.0337 |
Echinococcus multilocularis | FTZ F1 nuclear receptor protein | 0.0011 | 0.0121 | 0.0121 |
Brugia malayi | Nuclear hormone receptor family member nhr-41 | 0.0011 | 0.0121 | 0.0337 |
Echinococcus granulosus | nuclear receptor 2DBD gamma | 0.0011 | 0.0121 | 0.0121 |
Brugia malayi | Ligand-binding domain of nuclear hormone receptor family protein | 0.0011 | 0.0121 | 0.0337 |
Brugia malayi | ecdysteroid receptor | 0.0011 | 0.0121 | 0.0337 |
Brugia malayi | Nuclear hormone receptor family member nhr-31 | 0.0011 | 0.0121 | 0.0337 |
Schistosoma mansoni | hypothetical protein | 0.005 | 0.1043 | 0.1043 |
Echinococcus multilocularis | diuretic hormone 44 receptor GPRdih2 | 0.005 | 0.1043 | 0.1043 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0041 | 0.0838 | 0.3432 |
Schistosoma mansoni | thyroid hormone receptor | 0.0011 | 0.0121 | 0.0121 |
Schistosoma mansoni | hypothetical protein | 0.0357 | 0.8356 | 0.8356 |
Echinococcus granulosus | geminin | 0.0357 | 0.8356 | 0.8356 |
Schistosoma mansoni | thyroid hormone receptor | 0.0011 | 0.0121 | 0.0121 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-1 | 0.0011 | 0.0121 | 0.0337 |
Trypanosoma brucei | unspecified product | 0.0028 | 0.0536 | 0.1887 |
Echinococcus granulosus | histone acetyltransferase MYST2 | 0.0057 | 0.121 | 0.121 |
Brugia malayi | MH1 domain containing protein | 0.0008 | 0.0066 | 0.0183 |
Brugia malayi | photoreceptor-specific nuclear receptor | 0.0011 | 0.0121 | 0.0337 |
Loa Loa (eye worm) | Smad1 | 0.0008 | 0.0066 | 0.0183 |
Schistosoma mansoni | aldehyde dehydrogenase | 0.0063 | 0.1358 | 0.1358 |
Echinococcus multilocularis | FTZ F1 alpha | 0.0011 | 0.0121 | 0.0121 |
Schistosoma mansoni | tar DNA-binding protein | 0.013 | 0.2968 | 0.2968 |
Echinococcus granulosus | polycomb protein SCMH1 | 0.005 | 0.1047 | 0.1047 |
Mycobacterium ulcerans | aldehyde dehydrogenase | 0.0063 | 0.1358 | 1 |
Brugia malayi | C2-HC type zinc finger protein C.e-MyT1 | 0.0057 | 0.121 | 0.3372 |
Loa Loa (eye worm) | hypothetical protein | 0.0011 | 0.0121 | 0.0337 |
Trypanosoma brucei | unspecified product | 0.0028 | 0.0536 | 0.1887 |
Echinococcus granulosus | histone lysine N methyltransferase MLL3 | 0.0009 | 0.0085 | 0.0085 |
Echinococcus multilocularis | hepatocyte nuclear factor 4 alpha | 0.0011 | 0.0121 | 0.0121 |
Loa Loa (eye worm) | RNA recognition domain-containing protein domain-containing protein | 0.013 | 0.2968 | 0.827 |
Trypanosoma cruzi | DNA polymerase kappa, putative | 0.0041 | 0.0838 | 0.3432 |
Loa Loa (eye worm) | hypothetical protein | 0.005 | 0.1047 | 0.2917 |
Schistosoma mansoni | cpg binding protein | 0.0032 | 0.0617 | 0.0617 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0028 | 0.0536 | 0.1887 |
Loa Loa (eye worm) | hypothetical protein | 0.0011 | 0.0121 | 0.0337 |
Echinococcus granulosus | mixed lineage leukemia protein mll | 0.0007 | 0.0042 | 0.0042 |
Echinococcus granulosus | COUP TF:Svp nuclear hormone receptor | 0.0011 | 0.0121 | 0.0121 |
Brugia malayi | Steroid receptor seven-up type 2 | 0.0011 | 0.0121 | 0.0337 |
Echinococcus multilocularis | nuclear receptor 2DBD gamma | 0.0011 | 0.0121 | 0.0121 |
Schistosoma mansoni | tyrosyl-DNA phosphodiesterase | 0.0072 | 0.157 | 0.157 |
Trypanosoma brucei | DNA polymerase eta, putative | 0.0095 | 0.2122 | 1 |
Echinococcus multilocularis | mixed lineage leukemia protein mll | 0.0007 | 0.0042 | 0.0042 |
Leishmania major | DNA polymerase eta, putative | 0.0067 | 0.1451 | 0.6568 |
Toxoplasma gondii | ImpB/MucB/SamB family protein | 0.0067 | 0.1451 | 1 |
Plasmodium falciparum | DNA repair protein REV1, putative | 0.0013 | 0.0167 | 0.5 |
Schistosoma mansoni | photoreceptor-specific nuclear receptor related | 0.0011 | 0.0121 | 0.0121 |
Schistosoma mansoni | smad1 5 8 and | 0.0008 | 0.0066 | 0.0066 |
Schistosoma mansoni | cpg binding protein | 0.0032 | 0.0617 | 0.0617 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0041 | 0.0838 | 0.3432 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0041 | 0.0838 | 0.3432 |
Echinococcus multilocularis | cpg binding protein | 0.0032 | 0.0617 | 0.0617 |
Schistosoma mansoni | aldehyde dehydrogenase | 0.0063 | 0.1358 | 0.1358 |
Loa Loa (eye worm) | hypothetical protein | 0.0107 | 0.241 | 0.6717 |
Activity type | Activity value | Assay description | Source | Reference |
---|---|---|---|---|
IC50 (functional) | = 6.2 uM | Inhibitory activity against graft vs host disease in rat. | ChEMBL. | No reference |
IC50 (binding) | = 11 uM | Inhibitory activity against protein kinase C from Jurkat cells. | ChEMBL. | No reference |
Inhibition (functional) | = 71 % | Inhibitory activity against graft vs host disease in rat. | ChEMBL. | No reference |
Inhibition (binding) | = 82 % | Inhibitory activity against protein kinase C from Jurkat cells. | ChEMBL. | No reference |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.