Detailed information for compound 1355633

Basic information

Technical information
  • TDR Targets ID: 1355633
  • Name: 2-(4-methoxyphenoxy)-8-[[(2R)-oxolan-2-yl]met hyl]pteridin-7-one
  • MW: 354.36 | Formula: C18H18N4O4
  • H donors: 0 H acceptors: 3 LogP: 1.74 Rotable bonds: 5
    Rule of 5 violations (Lipinski): 1
  • SMILES: COc1ccc(cc1)Oc1ncc2c(n1)n(C[C@H]1CCCO1)c(=O)cn2
  • InChi: 1S/C18H18N4O4/c1-24-12-4-6-13(7-5-12)26-18-20-9-15-17(21-18)22(16(23)10-19-15)11-14-3-2-8-25-14/h4-7,9-10,14H,2-3,8,11H2,1H3/t14-/m1/s1
  • InChiKey: BJSNSNQRQJPNKQ-CQSZACIVSA-N  


Substructure search Similarity search

Network

Hover on a compound node to display the structore

Synonyms

  • 2-(4-methoxyphenoxy)-8-[[(2R)-tetrahydrofuran-2-yl]methyl]pteridin-7-one
  • 2-(4-methoxyphenoxy)-8-[[(2R)-2-tetrahydrofuranyl]methyl]-7-pteridinone
  • 2-(4-methoxyphenoxy)-8-(tetrahydrofurfuryl)pteridin-7-one
  • NCGC00010600
  • PCOP-199477

Targets

Known targets for this compound

Species Target name Source Bibliographic reference
Homo sapiens aldehyde dehydrogenase 1 family, member A1 Starlite/ChEMBL No references
Homo sapiens cytochrome P450, family 3, subfamily A, polypeptide 4 Starlite/ChEMBL No references
Homo sapiens cytochrome P450, family 2, subfamily C, polypeptide 9 Starlite/ChEMBL No references
Homo sapiens cytochrome P450, family 1, subfamily A, polypeptide 2 Starlite/ChEMBL No references

Predicted pathogen targets for this compound

By orthology
Species Potential target Known druggable target/s Ortholog Group
Loa Loa (eye worm) cytochrome P450 family protein Get druggable targets OG5_126554 All targets in OG5_126554
Trypanosoma brucei gambiense cytochrome P450, putative Get druggable targets OG5_126554 All targets in OG5_126554
Leishmania mexicana cytochrome p450-like protein Get druggable targets OG5_126554 All targets in OG5_126554
Candida albicans cytochrome P450 556 Get druggable targets OG5_126554 All targets in OG5_126554
Loa Loa (eye worm) CYP4Cod1 Get druggable targets OG5_126554 All targets in OG5_126554
Trypanosoma brucei cytochrome P450, putative Get druggable targets OG5_126554 All targets in OG5_126554
Loa Loa (eye worm) cytochrome P450 family protein Get druggable targets OG5_126554 All targets in OG5_126554
Candida albicans Mitochondrial aldehyde dehydrogenase Get druggable targets OG5_126638 All targets in OG5_126638
Leishmania major cytochrome p450-like protein Get druggable targets OG5_126554 All targets in OG5_126554
Brugia malayi Cytochrome P450 family protein Get druggable targets OG5_126582 All targets in OG5_126582
Echinococcus multilocularis aldehyde dehydrogenase, mitochondrial Get druggable targets OG5_126638 All targets in OG5_126638
Mycobacterium ulcerans aldehyde dehydrogenase Get druggable targets OG5_126638 All targets in OG5_126638
Trypanosoma congolense cytochrome P450, putative Get druggable targets OG5_126554 All targets in OG5_126554
Candida albicans aldehyde dehydrogenase Get druggable targets OG5_126638 All targets in OG5_126638
Candida albicans closely related to C.maltosa N-alkane-inducible cytochrome P-450, alkane hydroxylating monooxygenase CYP52A3-b aka P450Alk1A (BA Get druggable targets OG5_126554 All targets in OG5_126554
Candida albicans aldehyde dehydrogenase Get druggable targets OG5_126638 All targets in OG5_126638
Mycobacterium tuberculosis Probable aldehyde dehydrogenase Get druggable targets OG5_126638 All targets in OG5_126638
Candida albicans Mitochondrial aldehyde dehydrogenase Get druggable targets OG5_126638 All targets in OG5_126638
Trypanosoma cruzi cytochrome P450, putative Get druggable targets OG5_126554 All targets in OG5_126554
Leishmania braziliensis aldehyde dehydrogenase, mitochondrial precursor Get druggable targets OG5_126638 All targets in OG5_126638
Leishmania donovani cytochrome p450-like protein Get druggable targets OG5_126554 All targets in OG5_126554
Mycobacterium ulcerans aldehyde dehydrogenase Get druggable targets OG5_126638 All targets in OG5_126638
Schistosoma japonicum Aldehyde dehydrogenase X, mitochondrial precursor, putative Get druggable targets OG5_126638 All targets in OG5_126638
Mycobacterium ulcerans aldehyde dehydrogenase Get druggable targets OG5_126638 All targets in OG5_126638
Candida albicans cytochrome P450 56 Get druggable targets OG5_126554 All targets in OG5_126554
Toxoplasma gondii aldehyde dehydrogenase Get druggable targets OG5_126638 All targets in OG5_126638
Mycobacterium ulcerans cytochrome P450 185A4 Cyp185A4 Get druggable targets OG5_126554 All targets in OG5_126554
Schistosoma japonicum Aldehyde dehydrogenase, mitochondrial precursor, putative Get druggable targets OG5_126638 All targets in OG5_126638
Candida albicans similar to C.maltosa N-alkane inducible cytochrome P-450, ALK8 CYP52A11 Get druggable targets OG5_126554 All targets in OG5_126554
Leishmania donovani aldehyde dehydrogenase, mitochondrial precursor Get druggable targets OG5_126638 All targets in OG5_126638
Leishmania infantum cytochrome p450-like protein Get druggable targets OG5_126554 All targets in OG5_126554
Leishmania mexicana aldehyde dehydrogenase, mitochondrial precursor Get druggable targets OG5_126638 All targets in OG5_126638
Loa Loa (eye worm) cytochrome P450 family protein Get druggable targets OG5_126582 All targets in OG5_126582
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_126554 All targets in OG5_126554
Trypanosoma cruzi cytochrome P450, putative Get druggable targets OG5_126554 All targets in OG5_126554
Schistosoma mansoni aldehyde dehydrogenase Get druggable targets OG5_126638 All targets in OG5_126638
Schistosoma mansoni aldehyde dehydrogenase Get druggable targets OG5_126638 All targets in OG5_126638
Leishmania major aldehyde dehydrogenase, mitochondrial precursor Get druggable targets OG5_126638 All targets in OG5_126638
Neospora caninum hypothetical protein Get druggable targets OG5_126638 All targets in OG5_126638
Leishmania braziliensis cytochrome p450-like protein Get druggable targets OG5_126554 All targets in OG5_126554
Echinococcus granulosus aldehyde dehydrogenase mitochondrial Get druggable targets OG5_126638 All targets in OG5_126638
Brugia malayi Cytochrome P450 family protein Get druggable targets OG5_126554 All targets in OG5_126554
Schistosoma japonicum ko:K00128 aldehyde dehydrogenase (NAD+) [EC1.2.1.3], putative Get druggable targets OG5_126638 All targets in OG5_126638
Candida albicans similar to C.maltosa N-alkane inducible cytochrome P-450, ALK8 CYP52A11 Get druggable targets OG5_126554 All targets in OG5_126554
Brugia malayi Cytochrome P450 family protein Get druggable targets OG5_126554 All targets in OG5_126554
Schistosoma japonicum Retinal dehydrogenase 1, putative Get druggable targets OG5_126638 All targets in OG5_126638
Leishmania infantum aldehyde dehydrogenase, mitochondrial precursor Get druggable targets OG5_126638 All targets in OG5_126638
By sequence similarity to non orthologous known druggable targets
Species Potential target Known druggable target Length Alignment span Identity
Mycobacterium tuberculosis Succinate-semialdehyde dehydrogenase [NADP+] dependent (SSDH) GabD1 aldehyde dehydrogenase 1 family, member A1 501 aa 456 aa 33.3 %
Brugia malayi Cytochrome P450 family protein cytochrome P450, family 1, subfamily A, polypeptide 2 516 aa 470 aa 26.2 %
Mycobacterium tuberculosis Probable cytochrome P450 136 Cyp136 cytochrome P450, family 2, subfamily C, polypeptide 9 490 aa 441 aa 21.8 %
Brugia malayi cytochrome P450 cytochrome P450, family 3, subfamily A, polypeptide 4 502 aa 492 aa 24.2 %
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Echinococcus multilocularis retinoic acid receptor rxr beta a retinoic acid receptor rxr alpha a retinoic acid receptor rxr alpha 0.0108 0.4116 0.223
Brugia malayi nuclear receptor RXR 0.0108 0.4116 0.4116
Echinococcus granulosus Nuclear hormone receptor HR96 0.0108 0.4116 0.223
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0229 1 1
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.0229 1 1
Echinococcus granulosus FTZ F1 alpha 0.0229 1 1
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.0229 1 1
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.0229 1 1
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0108 0.4116 0.223
Loa Loa (eye worm) hypothetical protein 0.0121 0.4746 0.4746
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.0229 1 1
Brugia malayi Nuclear hormone receptor family member nhr-41 0.0229 1 1
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.0229 1 1
Loa Loa (eye worm) hypothetical protein 0.0108 0.4116 0.4116
Loa Loa (eye worm) hypothetical protein 0.0121 0.4746 0.4746
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0229 1 1
Mycobacterium ulcerans aldehyde dehydrogenase 0.0073 0.2427 1
Brugia malayi nuclear receptor NHR-88 0.0229 1 1
Brugia malayi Nuclear hormone receptor family member nhr-40 0.0229 1 1
Loa Loa (eye worm) hypothetical protein 0.0108 0.4116 0.4116
Brugia malayi nuclear receptor NHR-67 0.0108 0.4116 0.4116
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0229 1 1
Brugia malayi Nuclear hormone receptor family member nhr-14 0.0229 1 1
Loa Loa (eye worm) hypothetical protein 0.0108 0.4116 0.4116
Loa Loa (eye worm) hypothetical protein 0.0229 1 1
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.0229 1 1
Loa Loa (eye worm) hypothetical protein 0.0108 0.4116 0.4116
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.0229 1 1
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.0229 1 1
Loa Loa (eye worm) hypothetical protein 0.0229 1 1
Brugia malayi nuclear hormone receptor 0.0229 1 1
Brugia malayi Steroid receptor seven-up type 2 0.0229 1 1
Echinococcus granulosus nuclear receptor nhr 48 0.0108 0.4116 0.223
Schistosoma mansoni retinoic acid receptor RXR 0.0229 1 1
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0121 0.4746 0.3062
Brugia malayi Nuclear hormone receptor-like 1 0.0121 0.4746 0.4746
Onchocerca volvulus Bile acid receptor homolog 0.0229 1 1
Loa Loa (eye worm) hypothetical protein 0.0121 0.4746 0.4746
Brugia malayi steroid hormone receptor 0.0229 1 1
Brugia malayi tailless protein 0.0108 0.4116 0.4116
Brugia malayi hypothetical protein 0.0108 0.4116 0.4116
Echinococcus granulosus thyroid hormone receptor alpha 0.0108 0.4116 0.223
Loa Loa (eye worm) hypothetical protein 0.0108 0.4116 0.4116
Loa Loa (eye worm) cytochrome P450 family protein 0.0036 0.0606 0.0606
Schistosoma mansoni thyroid hormone receptor 0.0229 1 1
Loa Loa (eye worm) hypothetical protein 0.0108 0.4116 0.4116
Schistosoma mansoni nuclear receptor 0.0108 0.4116 0.223
Trypanosoma cruzi cytochrome P450, putative 0.0023 0 0.5
Loa Loa (eye worm) hypothetical protein 0.0108 0.4116 0.4116
Brugia malayi nuclear receptor subfamily 1, group D, member 1, putative 0.0108 0.4116 0.4116
Schistosoma mansoni nuclear hormone receptor 0.0108 0.4116 0.223
Loa Loa (eye worm) hypothetical protein 0.0229 1 1
Loa Loa (eye worm) hypothetical protein 0.0121 0.4746 0.4746
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.0229 1 1
Loa Loa (eye worm) nuclear hormone receptor-like 1 0.0121 0.4746 0.4746
Brugia malayi nuclear hormone receptor 0.0108 0.4116 0.4116
Schistosoma mansoni coup transcription factor 0.0229 1 1
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0108 0.4116 0.223
Loa Loa (eye worm) hypothetical protein 0.0108 0.4116 0.4116
Schistosoma mansoni Tr4/Tr2 (homologue) 0.0229 1 1
Schistosoma mansoni nuclear hormone receptor 0.0108 0.4116 0.223
Loa Loa (eye worm) nuclear hormone receptor 0.0108 0.4116 0.4116
Echinococcus multilocularis nuclear receptor nhr 48 0.0108 0.4116 0.223
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.0229 1 1
Loa Loa (eye worm) nuclear receptor NHR-67 0.0108 0.4116 0.4116
Mycobacterium ulcerans aldehyde dehydrogenase 0.0073 0.2427 1
Echinococcus granulosus ecdysone induced protein 78C 0.0229 1 1
Schistosoma mansoni zinc finger protein 0.0108 0.4116 0.223
Schistosoma mansoni nuclear hormone receptor superfamily protein-related 0.0108 0.4116 0.223
Brugia malayi Nuclear hormone receptor-like 1 0.0229 1 1
Schistosoma mansoni thyroid hormone receptor 0.0229 1 1
Brugia malayi orphan nuclear receptor NR2E1 0.0108 0.4116 0.4116
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.0229 1 1
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.0229 1 1
Schistosoma mansoni hepatocyte nuclear factor 4-alpha (hnf-4-alpha) 0.0108 0.4116 0.223
Echinococcus multilocularis nuclear receptor subfamily 4 group A 0.0108 0.4116 0.223
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.0229 1 1
Mycobacterium tuberculosis Probable aldehyde dehydrogenase 0.0073 0.2427 0.5
Echinococcus multilocularis thyroid hormone receptor alpha 0.0229 1 1
Loa Loa (eye worm) hypothetical protein 0.0229 1 1
Trypanosoma cruzi cytochrome P450, putative 0.0023 0 0.5
Brugia malayi conserved hypotetical protein 0.0108 0.4116 0.4116
Brugia malayi Nuclear hormone receptor family member nhr-49 0.0229 1 1
Brugia malayi nuclear hormone receptor family member odr-7 0.0108 0.4116 0.4116
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0229 1 1
Schistosoma mansoni ecdysone-induced protein 78c (dr-78) 0.0121 0.4746 0.3062
Loa Loa (eye worm) hypothetical protein 0.0108 0.4116 0.4116
Onchocerca volvulus Protein ultraspiracle homolog 0.0229 1 1
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.0229 1 1
Loa Loa (eye worm) hypothetical protein 0.0229 1 1
Schistosoma mansoni RAR-like nuclear receptor 0.0229 1 1
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.0229 1 1
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0229 1 1
Loa Loa (eye worm) hypothetical protein 0.0108 0.4116 0.4116
Trypanosoma brucei cytochrome P450, putative 0.0023 0 0.5
Brugia malayi ecdysone receptor 0.0108 0.4116 0.4116
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.0229 1 1
Echinococcus granulosus Nuclear hormone receptor HR96 0.0108 0.4116 0.223
Brugia malayi Nuclear hormone receptor-like 1 0.0121 0.4746 0.4746
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.0229 1 1
Loa Loa (eye worm) hypothetical protein 0.0108 0.4116 0.4116
Loa Loa (eye worm) hypothetical protein 0.0229 1 1
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0229 1 1
Brugia malayi Nuclear hormone receptor family member nhr-1 0.0229 1 1
Echinococcus multilocularis nuclear receptor subfamily 1 group D 0.0121 0.4746 0.3062
Schistosoma mansoni nuclear hormone receptor 0.0229 1 1
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0229 1 1
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.0229 1 1
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.0229 1 1
Loa Loa (eye worm) hypothetical protein 0.0108 0.4116 0.4116
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0229 1 1
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0108 0.4116 0.223
Echinococcus granulosus retinoic acid receptor rxr beta a 0.0229 1 1
Brugia malayi nuclear hormone receptor family member nhr-6 0.0108 0.4116 0.4116
Schistosoma mansoni steroid hormone receptor ad4bp 0.0229 1 1
Echinococcus multilocularis FTZ F1 alpha 0.0229 1 1
Toxoplasma gondii aldehyde dehydrogenase 0.0073 0.2427 0.5
Echinococcus multilocularis ecdysone induced protein 78C 0.0229 1 1
Brugia malayi Nuclear hormone receptor family member nhr-3 0.0229 1 1
Brugia malayi Nuclear hormone receptor E75 0.0108 0.4116 0.4116
Brugia malayi nuclear receptor RXR 0.0121 0.4746 0.4746
Loa Loa (eye worm) hypothetical protein 0.0121 0.4746 0.4746
Brugia malayi photoreceptor-specific nuclear receptor 0.0229 1 1
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0229 1 1
Loa Loa (eye worm) DR-78 0.0108 0.4116 0.4116
Loa Loa (eye worm) nuclear receptor nhr-7B 0.0108 0.4116 0.4116
Loa Loa (eye worm) steroid hormone receptor 0.0229 1 1
Loa Loa (eye worm) hypothetical protein 0.0229 1 1
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0229 1 1
Brugia malayi hypothetical protein 0.0121 0.4746 0.4746
Mycobacterium ulcerans aldehyde dehydrogenase 0.0073 0.2427 1
Schistosoma mansoni nuclear receptor nhr-48 0.0108 0.4116 0.223
Brugia malayi Nuclear hormone receptor family member nhr-31 0.0229 1 1
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.0229 1 1
Loa Loa (eye worm) hypothetical protein 0.0108 0.4116 0.4116
Echinococcus granulosus nuclear receptor subfamily 1 group D 0.0121 0.4746 0.3062
Brugia malayi nuclear receptor NHR-88 0.0108 0.4116 0.4116
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0229 1 1
Onchocerca volvulus 0.0229 1 1
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0108 0.4116 0.223
Echinococcus granulosus nuclear receptor subfamily 4 group A 0.0108 0.4116 0.223
Brugia malayi hypothetical protein 0.0121 0.4746 0.4746
Brugia malayi hypothetical protein 0.0108 0.4116 0.4116
Leishmania major aldehyde dehydrogenase, mitochondrial precursor 0.0073 0.2427 1
Brugia malayi Cytochrome P450 family protein 0.0036 0.0606 0.0606
Schistosoma mansoni nuclear receptor 0.0108 0.4116 0.223
Brugia malayi Nuclear hormone receptor E75 0.0108 0.4116 0.4116
Loa Loa (eye worm) hypothetical protein 0.0229 1 1

Activities

Activity type Activity value Assay description Source Reference
AC50 (functional) PUBCHEM_BIOASSAY: Cytochrome panel assay with activity outcomes. (Class of assay: other) Panel member name: p450-cyp2d6 Compounds with AC50 equal or less than 10 uM are considered active ChEMBL. No reference
AC50 (functional) PUBCHEM_BIOASSAY: Cytochrome panel assay with activity outcomes. (Class of assay: other) Panel member name: p450-cyp2c19 Compounds with AC50 equal or less than 10 uM are considered active ChEMBL. No reference
AC50 (functional) = 6.309573445 uM PUBCHEM_BIOASSAY: Cytochrome panel assay with activity outcomes. (Class of assay: other) Panel member name: p450-cyp1a2 Compounds with AC50 equal or less than 10 uM are considered active ChEMBL. No reference
AC50 (functional) = 12.58925412 uM PUBCHEM_BIOASSAY: Cytochrome panel assay with activity outcomes. (Class of assay: other) Panel member name: p450-cyp3a4 Compounds with AC50 equal or less than 10 uM are considered active ChEMBL. No reference
AC50 (functional) = 19.95262315 uM PUBCHEM_BIOASSAY: Cytochrome panel assay with activity outcomes. (Class of assay: other) Panel member name: p450-cyp2c9 Compounds with AC50 equal or less than 10 uM are considered active ChEMBL. No reference
Potency (ADMET) = 12.5893 um PUBCHEM_BIOASSAY: qHTS Assay for Activators of Cytochrome P450 3A4. (Class of assay: confirmatory) [Related pubchem assays: 410 ] ChEMBL. No reference
Potency (ADMET) = 12.5893 um PUBCHEM_BIOASSAY: qHTS Assay for Inhibitors and Substrates of Cytochrome P450 3A4. (Class of assay: confirmatory) [Related pubchem assays: 410 ] ChEMBL. No reference
Potency (functional) = 14.1254 um PUBCHEM_BIOASSAY: qHTS Assay for Inhibitors of Aldehyde Dehydrogenase 1 (ALDH1A1). (Class of assay: confirmatory) [Related pubchem assays: 1030 (qHTS Validation Assay for Inhibitors of aldehyde dehydrogenase 1 (ALDH1A1))] ChEMBL. No reference
Potency (ADMET) = 19.9526 um PUBCHEM_BIOASSAY: qHTS Assay for Inhibitors and Substrates of Cytochrome P450 2C9. (Class of assay: confirmatory) [Related pubchem assays: 885, 884, 410 ] ChEMBL. No reference

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

Bibliographic References

No literature references available for this target.

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