Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Echinococcus multilocularis | hepatocyte nuclear factor 4 alpha | 0.0023 | 0.0328 | 0.0451 |
Schistosoma mansoni | nuclear hormone receptor | 0.0023 | 0.0328 | 0.0328 |
Mycobacterium ulcerans | methionyl-tRNA synthetase | 0.0042 | 0.0869 | 0.2308 |
Trypanosoma cruzi | cruzipain precursor, putative | 0.0048 | 0.1075 | 0.3122 |
Leishmania major | cathepsin L-like protease | 0.0048 | 0.1075 | 0.3122 |
Plasmodium falciparum | methionine--tRNA ligase | 0.0042 | 0.0869 | 1 |
Leishmania major | aldo-keto reductase-like protein | 0.0127 | 0.3419 | 1 |
Trichomonas vaginalis | aldo-keto reductase, putative | 0.0127 | 0.3419 | 1 |
Loa Loa (eye worm) | bone morphogenetic protein 1b | 0.0018 | 0.0175 | 0.0405 |
Echinococcus multilocularis | aldo keto reductase family 1, member B4 | 0.0127 | 0.3419 | 0.4701 |
Schistosoma mansoni | egf-like domain protein | 0.0018 | 0.0175 | 0.0175 |
Loa Loa (eye worm) | hypothetical protein | 0.0018 | 0.0175 | 0.0405 |
Loa Loa (eye worm) | hypothetical protein | 0.0023 | 0.0328 | 0.076 |
Trichomonas vaginalis | aldo-keto reductase, putative | 0.0127 | 0.3419 | 1 |
Brugia malayi | Cathepsin L-like precursor | 0.0013 | 0.0011 | 0.0026 |
Schistosoma mansoni | pol-related | 0.0127 | 0.3419 | 0.3419 |
Trichomonas vaginalis | alcohol dehydrogenase, putative | 0.0037 | 0.0729 | 0.2107 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0048 | 0.1075 | 0.0373 |
Loa Loa (eye worm) | oxidoreductase | 0.0127 | 0.3419 | 0.7917 |
Echinococcus granulosus | methionine tRNA synthetase | 0.0042 | 0.0869 | 0.1195 |
Trichomonas vaginalis | aldo-keto reductase, putative | 0.0037 | 0.0729 | 0.2107 |
Schistosoma mansoni | retinoic acid receptor RXR | 0.0023 | 0.0328 | 0.0328 |
Echinococcus granulosus | nuclear receptor 2DBD gamma | 0.0023 | 0.0328 | 0.0451 |
Schistosoma mansoni | nuclear receptor 2DBD-gamma | 0.0023 | 0.0328 | 0.0328 |
Entamoeba histolytica | hypothetical protein | 0.0027 | 0.0446 | 0.1276 |
Mycobacterium ulcerans | hypothetical protein | 0.0037 | 0.0729 | 0.1885 |
Trichomonas vaginalis | aldo-keto reductase, putative | 0.0127 | 0.3419 | 1 |
Onchocerca volvulus | 0.0127 | 0.3419 | 1 | |
Trypanosoma cruzi | aldo/keto reductase, putative | 0.0127 | 0.3419 | 1 |
Trypanosoma brucei | prostaglandin f synthase | 0.0127 | 0.3419 | 0.2901 |
Brugia malayi | glutamate-cysteine ligase modifier subunit | 0.0037 | 0.0729 | 0.1689 |
Echinococcus granulosus | aldo keto reductase family 1 member B4 | 0.0127 | 0.3419 | 0.4701 |
Brugia malayi | GTP-binding regulatory protein Gs alpha-S chain, putative | 0.0035 | 0.0662 | 0.1532 |
Schistosoma mansoni | cellular tumor antigen P53 | 0.0038 | 0.0751 | 0.0751 |
Brugia malayi | Nuclear hormone receptor family member nhr-19 | 0.0023 | 0.0328 | 0.076 |
Echinococcus granulosus | aldo keto reductase family 1, member B4 | 0.0037 | 0.0729 | 0.1003 |
Trichomonas vaginalis | aldo-keto reductase, putative | 0.0127 | 0.3419 | 1 |
Trypanosoma cruzi | aldo/keto reductase, putative | 0.0037 | 0.0729 | 0.2107 |
Loa Loa (eye worm) | glutamate-cysteine ligase modifier subunit | 0.0037 | 0.0729 | 0.1689 |
Echinococcus granulosus | aldo keto reductase family 1 member B4 | 0.0127 | 0.3419 | 0.4701 |
Treponema pallidum | methionyl-tRNA synthetase | 0.0016 | 0.0105 | 0.5 |
Echinococcus granulosus | nuclear receptor 2DBD gamma | 0.0023 | 0.0328 | 0.0451 |
Brugia malayi | nuclear hormone receptor | 0.0023 | 0.0328 | 0.076 |
Schistosoma mansoni | FTZ-F1 nuclear receptor-like protein | 0.0023 | 0.0328 | 0.0328 |
Loa Loa (eye worm) | hypothetical protein | 0.0023 | 0.0328 | 0.076 |
Loa Loa (eye worm) | papain family cysteine protease containing protein | 0.0013 | 0.0011 | 0.0026 |
Leishmania major | prostaglandin f synthase, putative | 0.0127 | 0.3419 | 1 |
Brugia malayi | ecdysteroid receptor | 0.0023 | 0.0328 | 0.076 |
Echinococcus granulosus | aldo keto reductase | 0.0127 | 0.3419 | 0.4701 |
Loa Loa (eye worm) | low-density lipoprotein receptor repeat class B containing protein | 0.0018 | 0.0175 | 0.0405 |
Schistosoma mansoni | hypothetical protein | 0.005 | 0.1115 | 0.1115 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0048 | 0.1075 | 0.0373 |
Schistosoma mansoni | hypothetical protein | 0.0027 | 0.0446 | 0.0446 |
Schistosoma mansoni | thyroid hormone receptor | 0.0215 | 0.6044 | 0.6044 |
Echinococcus multilocularis | thyroid hormone receptor alpha | 0.0215 | 0.6044 | 0.8311 |
Brugia malayi | Steroid receptor seven-up type 2 | 0.0023 | 0.0328 | 0.076 |
Schistosoma mansoni | potassium channel beta | 0.0037 | 0.0729 | 0.0729 |
Echinococcus multilocularis | cathepsin l cysteine peptidase | 0.0013 | 0.0011 | 0.0015 |
Echinococcus multilocularis | cathepsin L cysteine protease | 0.0013 | 0.0011 | 0.0015 |
Onchocerca volvulus | Protein ultraspiracle homolog | 0.0023 | 0.0328 | 0.0931 |
Schistosoma mansoni | leucyl-tRNA synthetase | 0.0016 | 0.0105 | 0.0105 |
Loa Loa (eye worm) | hypothetical protein | 0.0023 | 0.0328 | 0.076 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-14 | 0.0023 | 0.0328 | 0.076 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0035 | 0.0662 | 0.091 |
Loa Loa (eye worm) | hypothetical protein | 0.0023 | 0.0328 | 0.076 |
Echinococcus granulosus | Nuclear hormone receptor family member nhr 41 | 0.0023 | 0.0328 | 0.0451 |
Trichomonas vaginalis | aldo/keto reductase, putative | 0.0127 | 0.3419 | 1 |
Loa Loa (eye worm) | methionyl-tRNA synthetase | 0.0042 | 0.0869 | 0.2013 |
Echinococcus granulosus | retinoic acid receptor rxr beta a | 0.0023 | 0.0328 | 0.0451 |
Plasmodium vivax | methionine--tRNA ligase, putative | 0.0042 | 0.0869 | 1 |
Brugia malayi | Latrophilin receptor protein 2 | 0.005 | 0.1115 | 0.2582 |
Leishmania major | prostaglandin f2-alpha synthase/D-arabinose dehydrogenase | 0.0127 | 0.3419 | 1 |
Schistosoma mansoni | RAR-like nuclear receptor | 0.0023 | 0.0328 | 0.0328 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0048 | 0.1075 | 0.0373 |
Echinococcus multilocularis | laminin | 0.0018 | 0.0175 | 0.0241 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0048 | 0.1075 | 0.0373 |
Onchocerca volvulus | Steroid hormone receptor family member cnr14 homolog | 0.0023 | 0.0328 | 0.0931 |
Echinococcus multilocularis | nuclear receptor 2DBD gamma | 0.0023 | 0.0328 | 0.0451 |
Loa Loa (eye worm) | hypothetical protein | 0.0018 | 0.0175 | 0.0405 |
Brugia malayi | Nuclear hormone receptor family member nhr-3 | 0.0023 | 0.0328 | 0.076 |
Loa Loa (eye worm) | Papain cysteine protease/cathepsin propeptide inhibitor-containing protein | 0.0013 | 0.0011 | 0.0026 |
Trypanosoma cruzi | cysteine peptidase, clan CA, family C1, cathepsin L-like, putative | 0.0044 | 0.095 | 0.2754 |
Echinococcus multilocularis | aldo keto reductase family 1, member B4 | 0.0127 | 0.3419 | 0.4701 |
Brugia malayi | protein ZK524.3 | 0.0016 | 0.0105 | 0.0242 |
Toxoplasma gondii | aldose reductase, putative | 0.0127 | 0.3419 | 1 |
Echinococcus multilocularis | diuretic hormone 44 receptor GPRdih2 | 0.005 | 0.1115 | 0.1533 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0035 | 0.0662 | 0.091 |
Brugia malayi | Cathepsin L-like precursor | 0.0013 | 0.0011 | 0.0026 |
Brugia malayi | Cathepsin L-like precursor | 0.0013 | 0.0011 | 0.0026 |
Onchocerca volvulus | Bile acid receptor homolog | 0.0023 | 0.0328 | 0.0931 |
Toxoplasma gondii | calcium binding egf domain-containing protein | 0.0018 | 0.0175 | 0.0481 |
Brugia malayi | Nuclear hormone receptor family member nhr-25 | 0.0023 | 0.0328 | 0.076 |
Plasmodium falciparum | aldehyde reductase, putative | 0.0037 | 0.0729 | 0.8367 |
Loa Loa (eye worm) | hypothetical protein | 0.0107 | 0.2836 | 0.6567 |
Loa Loa (eye worm) | hypothetical protein | 0.005 | 0.1115 | 0.2582 |
Loa Loa (eye worm) | oxidoreductase | 0.0127 | 0.3419 | 0.7917 |
Plasmodium vivax | aldehyde reductase, putative | 0.0037 | 0.0729 | 0.8367 |
Mycobacterium leprae | PROBABLE OXIDOREDUCTASE | 0.0127 | 0.3419 | 1 |
Brugia malayi | Nuclear hormone receptor family member nhr-25 | 0.0023 | 0.0328 | 0.076 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-49 | 0.0023 | 0.0328 | 0.076 |
Brugia malayi | Nuclear hormone receptor family member nhr-31 | 0.0023 | 0.0328 | 0.076 |
Brugia malayi | methionyl-tRNA synthetase | 0.0042 | 0.0869 | 0.2013 |
Echinococcus multilocularis | aldo keto reductase family 1, member B4 | 0.0127 | 0.3419 | 0.4701 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-31 | 0.0023 | 0.0328 | 0.076 |
Treponema pallidum | leucyl-tRNA synthetase | 0.0016 | 0.0105 | 0.5 |
Mycobacterium tuberculosis | Methionyl-tRNA synthetase MetS (MetRS) (methionine--tRNA ligase) | 0.0042 | 0.0869 | 0.0521 |
Trichomonas vaginalis | aldo-keto reductase, putative | 0.0127 | 0.3419 | 1 |
Toxoplasma gondii | tRNA ligases class I (M) protein | 0.0016 | 0.0105 | 0.0275 |
Leishmania major | aldehyde reductase, putative,oxidoreductase, putative | 0.0127 | 0.3419 | 1 |
Echinococcus multilocularis | aldo keto reductase | 0.0127 | 0.3419 | 0.4701 |
Schistosoma mansoni | photoreceptor-specific nuclear receptor related | 0.0023 | 0.0328 | 0.0328 |
Loa Loa (eye worm) | tyrosyl-tRNA synthetase | 0.0026 | 0.0397 | 0.092 |
Schistosoma mansoni | hypothetical protein | 0.0107 | 0.2836 | 0.2836 |
Echinococcus multilocularis | aldo keto reductase family 1, member B4 | 0.0127 | 0.3419 | 0.4701 |
Echinococcus multilocularis | aldo keto reductase family 1, member B4 | 0.0127 | 0.3419 | 0.4701 |
Entamoeba histolytica | hypothetical protein | 0.0027 | 0.0446 | 0.1276 |
Schistosoma mansoni | nuclear hormone receptor nor-1/nor-2 | 0.0023 | 0.0328 | 0.0328 |
Loa Loa (eye worm) | hypothetical protein | 0.0023 | 0.0328 | 0.076 |
Echinococcus granulosus | laminin | 0.0018 | 0.0175 | 0.0241 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.0048 | 0.1075 | 0.3122 |
Echinococcus multilocularis | Basic leucine zipper (bZIP) transcription | 0.0027 | 0.0446 | 0.0613 |
Trichomonas vaginalis | aldo/keto reductase, putative | 0.0127 | 0.3419 | 1 |
Echinococcus multilocularis | methionine tRNA synthetase | 0.0042 | 0.0869 | 0.1195 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.0048 | 0.1075 | 0.3122 |
Trichomonas vaginalis | dihydrodiol dehydrogenase, putative | 0.0127 | 0.3419 | 1 |
Brugia malayi | calcium-independent alpha-latrotoxin receptor 2, putative | 0.005 | 0.1115 | 0.2582 |
Brugia malayi | oxidoreductase, aldo/keto reductase family protein | 0.0127 | 0.3419 | 0.7917 |
Echinococcus granulosus | methionyl tRNA synthetase cytoplasmic | 0.0016 | 0.0105 | 0.0144 |
Echinococcus multilocularis | aldo keto reductase | 0.0127 | 0.3419 | 0.4701 |
Loa Loa (eye worm) | hypothetical protein | 0.0016 | 0.0105 | 0.0242 |
Echinococcus granulosus | cathepsin l1 | 0.0013 | 0.0011 | 0.0015 |
Echinococcus multilocularis | ecdysone induced protein 78C | 0.0023 | 0.0328 | 0.0451 |
Schistosoma mansoni | steroid hormone receptor ad4bp | 0.0023 | 0.0328 | 0.0328 |
Onchocerca volvulus | 0.0026 | 0.0397 | 0.1133 | |
Brugia malayi | latrophilin 2 splice variant baaae | 0.0107 | 0.2836 | 0.6567 |
Chlamydia trachomatis | methionine--tRNA ligase | 0.0016 | 0.0105 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0016 | 0.0105 | 0.0242 |
Schistosoma mansoni | aldo-keto reductase | 0.0127 | 0.3419 | 0.3419 |
Brugia malayi | Fibulin-1 precursor | 0.0018 | 0.0175 | 0.0405 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0035 | 0.0662 | 0.0662 |
Loa Loa (eye worm) | steroid hormone receptor | 0.0023 | 0.0328 | 0.076 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0035 | 0.0662 | 0.091 |
Toxoplasma gondii | aldo/keto reductase family oxidoreductase | 0.0037 | 0.0729 | 0.2107 |
Echinococcus multilocularis | voltage gated potassium channel subunit | 0.0037 | 0.0729 | 0.1003 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0048 | 0.1075 | 0.0373 |
Echinococcus multilocularis | FTZ F1 nuclear receptor protein | 0.0023 | 0.0328 | 0.0451 |
Giardia lamblia | Methionyl-tRNA synthetase | 0.0042 | 0.0869 | 0.2308 |
Echinococcus multilocularis | nuclear receptor 2DBD gamma | 0.0023 | 0.0328 | 0.0451 |
Schistosoma mansoni | hypothetical protein | 0.005 | 0.1115 | 0.1115 |
Onchocerca volvulus | 0.0037 | 0.0729 | 0.2107 | |
Loa Loa (eye worm) | latrophilin receptor protein 2 | 0.005 | 0.1115 | 0.2582 |
Brugia malayi | Nuclear hormone receptor family member nhr-40 | 0.0023 | 0.0328 | 0.076 |
Echinococcus multilocularis | cathepsin l cysteine peptidase | 0.0013 | 0.0011 | 0.0015 |
Echinococcus multilocularis | COUP TF:Svp nuclear hormone receptor | 0.0023 | 0.0328 | 0.0451 |
Loa Loa (eye worm) | oxidoreductase | 0.0127 | 0.3419 | 0.7917 |
Echinococcus granulosus | aldo keto reductase | 0.0127 | 0.3419 | 0.4701 |
Onchocerca volvulus | 0.0127 | 0.3419 | 1 | |
Trichomonas vaginalis | aldo-keto reductase, putative | 0.0037 | 0.0729 | 0.2107 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0048 | 0.1075 | 0.0373 |
Loa Loa (eye worm) | GTP-binding regulatory protein Gs alpha-S chain | 0.0035 | 0.0662 | 0.1532 |
Onchocerca volvulus | 0.0127 | 0.3419 | 1 | |
Trypanosoma brucei | RNA helicase, putative | 0.0348 | 1 | 1 |
Echinococcus multilocularis | aldo keto reductase family 1, member B4 | 0.0127 | 0.3419 | 0.4701 |
Brugia malayi | Nuclear hormone receptor family member nhr-49 | 0.0023 | 0.0328 | 0.076 |
Leishmania major | cathepsin L-like protease | 0.0048 | 0.1075 | 0.3122 |
Wolbachia endosymbiont of Brugia malayi | methionyl-tRNA synthetase | 0.0042 | 0.0869 | 1 |
Echinococcus multilocularis | aldo keto reductase family 1, member B4 | 0.0127 | 0.3419 | 0.4701 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0048 | 0.1075 | 0.0373 |
Loa Loa (eye worm) | hypothetical protein | 0.0127 | 0.3419 | 0.7917 |
Trichomonas vaginalis | aldo-keto reductase, putative | 0.0127 | 0.3419 | 1 |
Leishmania major | leucyl-tRNA synthetase, putative | 0.0016 | 0.0105 | 0.0275 |
Loa Loa (eye worm) | pigment dispersing factor receptor c | 0.0157 | 0.4319 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0018 | 0.0175 | 0.0405 |
Entamoeba histolytica | aldose reductase, putative | 0.0127 | 0.3419 | 1 |
Brugia malayi | Calcitonin receptor-like protein seb-1 | 0.0157 | 0.4319 | 1 |
Echinococcus multilocularis | aldo keto reductase family 1, member B4 | 0.0127 | 0.3419 | 0.4701 |
Mycobacterium ulcerans | oxidoreductase | 0.0127 | 0.3419 | 1 |
Echinococcus granulosus | tumor protein p63 | 0.0256 | 0.7273 | 1 |
Trichomonas vaginalis | aldo-keto reductase, putative | 0.0127 | 0.3419 | 1 |
Brugia malayi | Ligand-binding domain of nuclear hormone receptor family protein | 0.0023 | 0.0328 | 0.076 |
Schistosoma mansoni | thyroid hormone receptor | 0.0215 | 0.6044 | 0.6044 |
Trichomonas vaginalis | aldo-keto reductase, putative | 0.0127 | 0.3419 | 1 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.0048 | 0.1075 | 0.3122 |
Entamoeba histolytica | aldose reductase, putative | 0.0127 | 0.3419 | 1 |
Brugia malayi | Cathepsin L-like precursor | 0.0013 | 0.0011 | 0.0026 |
Schistosoma mansoni | Tr4/Tr2 (homologue) | 0.0023 | 0.0328 | 0.0328 |
Echinococcus granulosus | aldo keto reductase family 1 member B4 | 0.0127 | 0.3419 | 0.4701 |
Plasmodium vivax | oxidoreductase, aldo/keto reductase domain containing protein | 0.0037 | 0.0729 | 0.8367 |
Echinococcus multilocularis | aldo keto reductase | 0.0127 | 0.3419 | 0.4701 |
Trichomonas vaginalis | aldo-keto reductase, putative | 0.0037 | 0.0729 | 0.2107 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-1 | 0.0023 | 0.0328 | 0.076 |
Loa Loa (eye worm) | hypothetical protein | 0.0023 | 0.0328 | 0.076 |
Brugia malayi | photoreceptor-specific nuclear receptor | 0.0023 | 0.0328 | 0.076 |
Loa Loa (eye worm) | hypothetical protein | 0.0157 | 0.4319 | 1 |
Chlamydia trachomatis | leucine--tRNA ligase | 0.0016 | 0.0105 | 0.5 |
Echinococcus granulosus | cathepsin l cysteine peptidase | 0.0013 | 0.0011 | 0.0015 |
Loa Loa (eye worm) | hypothetical protein | 0.0018 | 0.0175 | 0.0405 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-40 | 0.0023 | 0.0328 | 0.076 |
Brugia malayi | oxidoreductase, aldo/keto reductase family protein | 0.0127 | 0.3419 | 0.7917 |
Echinococcus multilocularis | GPCR, family 2 | 0.005 | 0.1115 | 0.1533 |
Echinococcus granulosus | aldo keto reductase family 1 member B4 | 0.0127 | 0.3419 | 0.4701 |
Echinococcus granulosus | FTZ F1 alpha | 0.0023 | 0.0328 | 0.0451 |
Echinococcus granulosus | aldo keto reductase family 1 member B4 | 0.0127 | 0.3419 | 0.4701 |
Schistosoma mansoni | aldo-keto reductase | 0.0127 | 0.3419 | 0.3419 |
Plasmodium vivax | methionine--tRNA ligase, putative | 0.0016 | 0.0105 | 0.109 |
Brugia malayi | Calcium binding EGF domain containing protein | 0.0018 | 0.0175 | 0.0405 |
Trypanosoma cruzi | aldo-keto reductase | 0.0127 | 0.3419 | 1 |
Entamoeba histolytica | hypothetical protein | 0.0027 | 0.0446 | 0.1276 |
Echinococcus multilocularis | leucyl tRNA synthetase | 0.0016 | 0.0105 | 0.0144 |
Echinococcus granulosus | hepatocyte nuclear factor 4 alpha | 0.0023 | 0.0328 | 0.0451 |
Echinococcus multilocularis | cathepsin L cysteine protease | 0.0013 | 0.0011 | 0.0015 |
Giardia lamblia | Aldose reductase | 0.0127 | 0.3419 | 1 |
Loa Loa (eye worm) | nuclear Hormone Receptor family member | 0.0023 | 0.0328 | 0.076 |
Trypanosoma brucei | aldo-keto reductase, putative | 0.0127 | 0.3419 | 0.2901 |
Onchocerca volvulus | 0.0127 | 0.3419 | 1 | |
Mycobacterium leprae | Conserved hypothetical protein | 0.009 | 0.2322 | 0.5922 |
Brugia malayi | Nuclear hormone receptor family member nhr-14 | 0.0023 | 0.0328 | 0.076 |
Loa Loa (eye worm) | oxidoreductase | 0.0127 | 0.3419 | 0.7917 |
Brugia malayi | Corticotropin releasing factor receptor 2 precursor, putative | 0.0157 | 0.4319 | 1 |
Brugia malayi | Ligand-binding domain of nuclear hormone receptor family protein | 0.0023 | 0.0328 | 0.076 |
Trypanosoma cruzi | methionyl-tRNA synthetase, putative | 0.0042 | 0.0869 | 0.2519 |
Schistosoma mansoni | methionine-tRNA synthetase | 0.0016 | 0.0105 | 0.0105 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0035 | 0.0662 | 0.0662 |
Echinococcus granulosus | COUP TF:Svp nuclear hormone receptor | 0.0023 | 0.0328 | 0.0451 |
Echinococcus granulosus | aldo keto reductase family 1 member B4 | 0.0127 | 0.3419 | 0.4701 |
Echinococcus granulosus | GPCR family 2 | 0.005 | 0.1115 | 0.1533 |
Trichomonas vaginalis | aldo-keto reductase, putative | 0.0127 | 0.3419 | 1 |
Loa Loa (eye worm) | ctsf protein | 0.0013 | 0.0011 | 0.0026 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0048 | 0.1075 | 0.0373 |
Brugia malayi | NADH-dependent xylose reductase | 0.0037 | 0.0729 | 0.1689 |
Schistosoma mansoni | hypothetical protein | 0.0192 | 0.5349 | 0.5349 |
Brugia malayi | Nuclear hormone receptor family member nhr-1 | 0.0023 | 0.0328 | 0.076 |
Echinococcus multilocularis | cysteine protease | 0.0013 | 0.0011 | 0.0015 |
Echinococcus granulosus | Mitotic checkpoint protein PRCC C terminal | 0.0192 | 0.5349 | 0.7354 |
Echinococcus granulosus | Basic leucine zipper bZIP transcription | 0.0027 | 0.0446 | 0.0613 |
Schistosoma mansoni | transcription factor LCR-F1 | 0.0027 | 0.0446 | 0.0446 |
Echinococcus multilocularis | Nuclear hormone receptor family member nhr 41 | 0.0023 | 0.0328 | 0.0451 |
Echinococcus granulosus | aldo keto reductase family 1 member B4 | 0.0127 | 0.3419 | 0.4701 |
Trichomonas vaginalis | aldo-keto reductase, putative | 0.0127 | 0.3419 | 1 |
Entamoeba histolytica | alcohol dehydrogenase, putative | 0.0037 | 0.0729 | 0.2107 |
Leishmania major | methionyl-tRNA synthetase, putative | 0.0042 | 0.0869 | 0.2519 |
Echinococcus multilocularis | aldo keto reductase family 1, member B4 | 0.0127 | 0.3419 | 0.4701 |
Loa Loa (eye worm) | hypothetical protein | 0.0023 | 0.0328 | 0.076 |
Trichomonas vaginalis | aldo-keto reductase, putative | 0.0127 | 0.3419 | 1 |
Brugia malayi | Nuclear hormone receptor family member nhr-41 | 0.0023 | 0.0328 | 0.076 |
Echinococcus granulosus | diuretic hormone 44 receptor GPRdih2 | 0.005 | 0.1115 | 0.1533 |
Onchocerca volvulus | 0.0038 | 0.0751 | 0.217 | |
Schistosoma mansoni | coup transcription factor | 0.0023 | 0.0328 | 0.0328 |
Brugia malayi | steroid hormone receptor | 0.0023 | 0.0328 | 0.076 |
Trichomonas vaginalis | aldo-keto reductase, putative | 0.0127 | 0.3419 | 1 |
Giardia lamblia | Aldose reductase | 0.0127 | 0.3419 | 1 |
Echinococcus multilocularis | fibrillin 1 | 0.0018 | 0.0175 | 0.0241 |
Echinococcus multilocularis | cysteine protease | 0.0013 | 0.0011 | 0.0015 |
Echinococcus granulosus | voltage gated potassium channel subunit | 0.0037 | 0.0729 | 0.1003 |
Echinococcus granulosus | cathepsin L cysteine proteinase | 0.0013 | 0.0011 | 0.0015 |
Loa Loa (eye worm) | oxidoreductase | 0.0127 | 0.3419 | 0.7917 |
Echinococcus granulosus | aldo keto reductase family 1 member B4 | 0.0127 | 0.3419 | 0.4701 |
Entamoeba histolytica | methionyl-tRNA synthetase, putative | 0.0016 | 0.0105 | 0.0275 |
Echinococcus multilocularis | aldehyde reductase | 0.009 | 0.2322 | 0.3193 |
Echinococcus multilocularis | aldo keto reductase family 1, member B4 | 0.0127 | 0.3419 | 0.4701 |
Echinococcus granulosus | ecdysone induced protein 78C | 0.0023 | 0.0328 | 0.0451 |
Echinococcus granulosus | aldo keto reductase family 1 member B4 | 0.0127 | 0.3419 | 0.4701 |
Onchocerca volvulus | 0.0127 | 0.3419 | 1 | |
Brugia malayi | Low-density lipoprotein receptor repeat class B containing protein | 0.0018 | 0.0175 | 0.0405 |
Echinococcus granulosus | cadherin EGF LAG seven pass G type receptor | 0.005 | 0.1115 | 0.1533 |
Brugia malayi | Cathepsin L-like precursor | 0.0013 | 0.0011 | 0.0026 |
Leishmania major | aldo/keto reductase, putative,aldo/keto reductase family-like protein | 0.0037 | 0.0729 | 0.2107 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0035 | 0.0662 | 0.0662 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0035 | 0.0662 | 0.091 |
Echinococcus multilocularis | tumor protein p63 | 0.0256 | 0.7273 | 1 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0048 | 0.1075 | 0.0373 |
Loa Loa (eye worm) | hypothetical protein | 0.0023 | 0.0328 | 0.076 |
Echinococcus granulosus | hypothetical protein | 0.0127 | 0.3419 | 0.4701 |
Loa Loa (eye worm) | cysteine protease | 0.0013 | 0.0011 | 0.0026 |
Echinococcus multilocularis | methionyl tRNA synthetase, cytoplasmic | 0.0016 | 0.0105 | 0.0144 |
Trichomonas vaginalis | methionine-tRNA synthetase, putative | 0.0042 | 0.0869 | 0.2519 |
Loa Loa (eye worm) | fibroinase | 0.0013 | 0.0011 | 0.0026 |
Trichomonas vaginalis | dihydrodiol dehydrogenase, putative | 0.0127 | 0.3419 | 1 |
Plasmodium vivax | hypothetical protein, conserved | 0.0016 | 0.0105 | 0.109 |
Brugia malayi | hypothetical protein | 0.0027 | 0.0446 | 0.1033 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0048 | 0.1075 | 0.0373 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0037 | 0.0729 | 0.2107 |
Schistosoma mansoni | cathepsin F (C01 family) | 0.0013 | 0.0011 | 0.0011 |
Loa Loa (eye worm) | hypothetical protein | 0.0013 | 0.0011 | 0.0026 |
Brugia malayi | Papain family cysteine protease containing protein | 0.0013 | 0.0011 | 0.0026 |
Entamoeba histolytica | aldose reductase, putative | 0.0127 | 0.3419 | 1 |
Leishmania major | cathepsin L-like protease | 0.0048 | 0.1075 | 0.3122 |
Echinococcus granulosus | FTZ F1 nuclear receptor protein | 0.0023 | 0.0328 | 0.0451 |
Entamoeba histolytica | alcohol dehydrogenase, putative | 0.0037 | 0.0729 | 0.2107 |
Brugia malayi | Cathepsin L-like precursor | 0.0013 | 0.0011 | 0.0026 |
Trypanosoma brucei | methionyl-tRNA synthetase, putative | 0.0042 | 0.0869 | 0.0151 |
Schistosoma mansoni | hypothetical protein | 0.005 | 0.1115 | 0.1115 |
Toxoplasma gondii | oxidoreductase, aldo/keto reductase family protein | 0.0037 | 0.0729 | 0.2107 |
Loa Loa (eye worm) | hypothetical protein | 0.0018 | 0.0175 | 0.0405 |
Mycobacterium leprae | Probable methionyl-tRNA synthase MetS | 0.0042 | 0.0869 | 0.0521 |
Toxoplasma gondii | methionyl-tRNA synthetase | 0.0042 | 0.0869 | 0.2519 |
Brugia malayi | Nuclear hormone receptor-like 1 | 0.0023 | 0.0328 | 0.076 |
Schistosoma mansoni | cathepsin F (C01 family) | 0.0013 | 0.0011 | 0.0011 |
Onchocerca volvulus | 0.0127 | 0.3419 | 1 | |
Echinococcus multilocularis | FTZ F1 alpha | 0.0023 | 0.0328 | 0.0451 |
Brugia malayi | oxidoreductase, aldo/keto reductase family protein | 0.0127 | 0.3419 | 0.7917 |
Onchocerca volvulus | Arrow homolog | 0.0018 | 0.0175 | 0.0481 |
Schistosoma mansoni | methionine-tRNA synthetase | 0.0042 | 0.0869 | 0.0869 |
Brugia malayi | Nuclear hormone receptor family member nhr-19 | 0.0023 | 0.0328 | 0.076 |
Echinococcus granulosus | Tolloid protein 1 | 0.0018 | 0.0175 | 0.0241 |
Onchocerca volvulus | 0.0023 | 0.0328 | 0.0931 | |
Schistosoma mansoni | subfamily M12A unassigned peptidase (M12 family) | 0.0018 | 0.0175 | 0.0175 |
Echinococcus multilocularis | aldo keto reductase family 1, member B4 | 0.0127 | 0.3419 | 0.4701 |
Loa Loa (eye worm) | hypothetical protein | 0.0016 | 0.0105 | 0.0242 |
Loa Loa (eye worm) | hypothetical protein | 0.0038 | 0.0751 | 0.1738 |
Entamoeba histolytica | hypothetical protein | 0.0027 | 0.0446 | 0.1276 |
Echinococcus multilocularis | Mitotic checkpoint protein PRCC, C terminal | 0.0192 | 0.5349 | 0.7354 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0048 | 0.1075 | 0.0373 |
Toxoplasma gondii | aldo-keto reductase | 0.0037 | 0.0729 | 0.2107 |
Mycobacterium tuberculosis | Probable oxidoreductase | 0.0127 | 0.3419 | 1 |
Loa Loa (eye worm) | multiple epidermal growth factor-like domains 6 | 0.0018 | 0.0175 | 0.0405 |
Trypanosoma cruzi | major cysteine proteinase, putative | 0.0038 | 0.0766 | 0.2216 |
Brugia malayi | methionyl-tRNA synthetase | 0.0016 | 0.0105 | 0.0242 |
Echinococcus granulosus | aldehyde reductase | 0.009 | 0.2322 | 0.3193 |
Echinococcus multilocularis | cadherin EGF LAG seven pass G type receptor | 0.005 | 0.1115 | 0.1533 |
Plasmodium falciparum | methionine--tRNA ligase, putative | 0.0016 | 0.0105 | 0.109 |
Schistosoma mansoni | hypothetical protein | 0.005 | 0.1115 | 0.1115 |
Echinococcus granulosus | aldo keto reductase | 0.0127 | 0.3419 | 0.4701 |
Brugia malayi | oxidoreductase, aldo/keto reductase family protein | 0.0127 | 0.3419 | 0.7917 |
Toxoplasma gondii | calcium binding egf domain-containing protein | 0.0018 | 0.0175 | 0.0481 |
Schistosoma mansoni | retinoid-x-receptor (RXR) | 0.0023 | 0.0328 | 0.0328 |
Echinococcus multilocularis | Tolloid protein 1 | 0.0018 | 0.0175 | 0.0241 |
Trichomonas vaginalis | aldo/keto reductase, putative | 0.0127 | 0.3419 | 1 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-41 | 0.0023 | 0.0328 | 0.076 |
Plasmodium falciparum | aldo-keto reductase, putative | 0.0037 | 0.0729 | 0.8367 |
Echinococcus multilocularis | aldo keto reductase | 0.0127 | 0.3419 | 0.4701 |
Trichomonas vaginalis | dihydrodiol dehydrogenase, putative | 0.0127 | 0.3419 | 1 |
Brugia malayi | nuclear receptor NHR-88 | 0.0023 | 0.0328 | 0.076 |
Activity type | Activity value | Assay description | Source | Reference |
---|---|---|---|---|
Potency (functional) | = 100 um | PUBCHEM_BIOASSAY: qHTS Inhibitors of AmpC Beta-Lactamase (assay with detergent). (Class of assay: confirmatory) [Related pubchem assays: 1002 (Confirmation Concentration-Response Assay for Inhibitors of AmpC Beta-Lactamase (assay with detergent)), 585 (Promiscuous and Specific Inhibitors of AmpC Beta-Lactamase (assay without detergent) - a screen old NIH MLSMR collection), 584 (Promiscuous and Specific Inhibitors of AmpC Beta-Lactamase (assay with detergent) - a screen of the old NIH MLSMR collection), 1003 (Confirmation Cuvette-Based Assay for Inhibitors of AmpC Beta-Lactamase (assay with detergent))] | ChEMBL. | No reference |
Potency (functional) | 100 uM | PUBCHEM_BIOASSAY: qHTS Assay for Inhibitors of Mammalian Selenoprotein Thioredoxin Reductase 1 (TrxR1): qHTS. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID488771] | ChEMBL. | No reference |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.