Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Echinococcus multilocularis | RUN | 0.0022 | 0.037 | 0.0339 |
Schistosoma mansoni | hypothetical protein | 0.0017 | 0.0209 | 0.0209 |
Entamoeba histolytica | recQ family helicase, putative | 0.0026 | 0.0492 | 0.5554 |
Onchocerca volvulus | Eukaryotic initiation factor 4A homolog | 0.0028 | 0.0564 | 0.0443 |
Plasmodium falciparum | LCCL domain-containing protein | 0.0022 | 0.037 | 0.1988 |
Echinococcus multilocularis | ATP dependent DNA helicase Q5 | 0.002 | 0.0308 | 0.0276 |
Trichomonas vaginalis | ran, putative | 0.0022 | 0.0392 | 0.0738 |
Trichomonas vaginalis | DNA helicase recq, putative | 0.0048 | 0.12 | 1 |
Toxoplasma gondii | isocitrate dehydrogenase | 0.0017 | 0.021 | 0.1163 |
Schistosoma mansoni | transcription factor LCR-F1 | 0.0038 | 0.0886 | 0.0886 |
Loa Loa (eye worm) | hypothetical protein | 0.002 | 0.0308 | 0.0276 |
Leishmania major | DNA polymerase kappa, putative | 0.002 | 0.0327 | 0.0727 |
Echinococcus multilocularis | GA binding protein alpha chain | 0.0077 | 0.2108 | 0.2082 |
Leishmania major | DNA polymerase eta, putative | 0.0033 | 0.0735 | 0.3256 |
Loa Loa (eye worm) | hypothetical protein | 0.0047 | 0.1181 | 0.1153 |
Mycobacterium tuberculosis | Probable short-chain type dehydrogenase/reductase | 0.0068 | 0.1823 | 1 |
Schistosoma mansoni | ran | 0.0022 | 0.0392 | 0.0392 |
Echinococcus multilocularis | GPCR, family 2 | 0.0017 | 0.0209 | 0.0177 |
Schistosoma mansoni | hypothetical protein | 0.0022 | 0.037 | 0.037 |
Trypanosoma brucei | Eukaryotic initiation factor 4A-1 | 0.0028 | 0.0564 | 0.4149 |
Plasmodium falciparum | eukaryotic initiation factor 4A | 0.0028 | 0.0564 | 0.4395 |
Echinococcus multilocularis | NADP dependent isocitrate dehydrogenase | 0.0017 | 0.021 | 0.0178 |
Loa Loa (eye worm) | hypothetical protein | 0.0017 | 0.0209 | 0.0177 |
Plasmodium vivax | GTP-binding nuclear protein RAN/TC4, putative | 0.0022 | 0.0392 | 0.3649 |
Echinococcus granulosus | dna polymerase eta | 0.0047 | 0.1181 | 0.1153 |
Mycobacterium ulcerans | aldehyde dehydrogenase | 0.0067 | 0.1805 | 0.9881 |
Leishmania major | GTP-binding protein, putative | 0.0022 | 0.0392 | 0.1127 |
Echinococcus multilocularis | lipoxygenase domain containing protein | 0.0022 | 0.037 | 0.0339 |
Echinococcus multilocularis | bloom syndrome protein | 0.0048 | 0.12 | 0.1172 |
Schistosoma mansoni | aldehyde dehydrogenase | 0.0067 | 0.1805 | 0.1805 |
Brugia malayi | ImpB/MucB/SamB family protein | 0.0047 | 0.1181 | 0.1637 |
Trypanosoma cruzi | DNA polymerase kappa, putative | 0.002 | 0.0327 | 0.1208 |
Brugia malayi | ATP-dependent DNA helicase, RecQ family protein | 0.002 | 0.0308 | 0.0392 |
Echinococcus granulosus | RUN | 0.0022 | 0.037 | 0.0339 |
Brugia malayi | ATP-dependent DNA helicase, RecQ family protein | 0.002 | 0.0308 | 0.0392 |
Schistosoma mansoni | DNA helicase recq1 | 0.002 | 0.0308 | 0.0308 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.002 | 0.0327 | 0.1904 |
Entamoeba histolytica | Ran family GTPase | 0.0022 | 0.0392 | 0.4419 |
Schistosoma mansoni | rab6-interacting | 0.0022 | 0.037 | 0.037 |
Plasmodium vivax | flap endonuclease 1, putative | 0.0028 | 0.0553 | 0.6892 |
Entamoeba histolytica | hypothetical protein | 0.0038 | 0.0886 | 1 |
Leishmania major | 3-oxoacyl-(acyl-carrier protein) reductase, putative | 0.0068 | 0.1823 | 1 |
Trypanosoma cruzi | flap endonuclease-1 (FEN-1), putative | 0.0028 | 0.0553 | 0.3535 |
Trypanosoma brucei | flap endonuclease-1 (FEN-1), putative | 0.0028 | 0.0553 | 0.4047 |
Loa Loa (eye worm) | ImpB/MucB/SamB family protein | 0.002 | 0.0327 | 0.0296 |
Schistosoma mansoni | hypothetical protein | 0.0011 | 0.0032 | 0.0032 |
Echinococcus multilocularis | lipoxygenase domain containing protein | 0.0022 | 0.037 | 0.0339 |
Brugia malayi | hypothetical protein | 0.0022 | 0.037 | 0.0481 |
Echinococcus granulosus | NADP dependent isocitrate dehydrogenase | 0.0017 | 0.021 | 0.0178 |
Brugia malayi | ImpB/MucB/SamB family protein | 0.002 | 0.0327 | 0.042 |
Plasmodium falciparum | ADP-dependent DNA helicase RecQ | 0.0042 | 0.1016 | 1 |
Echinococcus granulosus | Basic leucine zipper bZIP transcription | 0.0038 | 0.0886 | 0.0857 |
Trypanosoma brucei | isocitrate dehydrogenase [NADP], mitochondrial precursor, putative | 0.0017 | 0.021 | 0.0791 |
Schistosoma mansoni | DEAD box ATP-dependent RNA helicase | 0.0028 | 0.0564 | 0.0564 |
Leishmania major | eukaryotic initiation factor 4a, putative | 0.0028 | 0.0564 | 0.2196 |
Echinococcus multilocularis | ATP dependent DNA helicase Q1 | 0.002 | 0.0308 | 0.0276 |
Echinococcus multilocularis | eukaryotic initiation factor 4A | 0.0028 | 0.0564 | 0.0533 |
Schistosoma mansoni | hypothetical protein | 0.0017 | 0.0209 | 0.0209 |
Brugia malayi | Fli-1 protein | 0.0233 | 0.7051 | 1 |
Schistosoma mansoni | ets-related | 0.0233 | 0.7051 | 0.7051 |
Toxoplasma gondii | isocitrate dehydrogenase | 0.0017 | 0.021 | 0.1163 |
Echinococcus multilocularis | isocitrate dehydrogenase | 0.0017 | 0.021 | 0.0178 |
Loa Loa (eye worm) | GTP-binding nuclear protein RAN/TC4 | 0.0022 | 0.0392 | 0.036 |
Mycobacterium ulcerans | aldehyde dehydrogenase | 0.0067 | 0.1805 | 0.9881 |
Echinococcus multilocularis | GTP binding nuclear protein Ran | 0.0022 | 0.0392 | 0.036 |
Schistosoma mansoni | hypothetical protein | 0.0011 | 0.0032 | 0.0032 |
Trichomonas vaginalis | DNA helicase recq1, putative | 0.0048 | 0.12 | 1 |
Schistosoma mansoni | polycystin 1-related | 0.0022 | 0.037 | 0.037 |
Echinococcus multilocularis | 3 hydroxyacyl coenzyme A dehydrogenase type 2 | 0.0068 | 0.1823 | 0.1796 |
Toxoplasma gondii | ATP-dependent DNA helicase, RecQ family protein | 0.002 | 0.0308 | 0.1705 |
Echinococcus multilocularis | isocitrate dehydrogenase 2 (NADP+) | 0.0017 | 0.021 | 0.0178 |
Loa Loa (eye worm) | hypothetical protein | 0.0028 | 0.0564 | 0.0533 |
Trypanosoma brucei | DNA polymerase IV, putative | 0.002 | 0.0327 | 0.1904 |
Mycobacterium ulcerans | short-chain type dehydrogenase/reductase | 0.0068 | 0.1823 | 1 |
Trypanosoma brucei | DNA polymerase eta, putative | 0.0047 | 0.1181 | 1 |
Echinococcus granulosus | bloom syndrome protein | 0.0048 | 0.12 | 0.1172 |
Leishmania major | ATP-dependent DEAD/H DNA helicase recQ, putative | 0.0026 | 0.0492 | 0.1751 |
Brugia malayi | Importin beta-1 subunit | 0.0031 | 0.0647 | 0.0876 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.002 | 0.0327 | 0.1904 |
Leishmania major | eukaryotic initiation factor 4a, putative | 0.0028 | 0.0564 | 0.2196 |
Entamoeba histolytica | hypothetical protein | 0.0025 | 0.0464 | 0.5235 |
Schistosoma mansoni | DNA polymerase eta | 0.0047 | 0.1181 | 0.1181 |
Schistosoma mansoni | gabp alpha | 0.0077 | 0.2108 | 0.2108 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.002 | 0.0327 | 0.1904 |
Brugia malayi | calcium-independent alpha-latrotoxin receptor 2, putative | 0.0017 | 0.0209 | 0.0252 |
Echinococcus granulosus | terminal deoxycytidyl transferase rev1 | 0.002 | 0.0327 | 0.0296 |
Trichomonas vaginalis | Importin beta-1 subunit, putative | 0.0025 | 0.0464 | 0.1567 |
Mycobacterium ulcerans | short-chain type dehydrogenase/reductase | 0.0068 | 0.1823 | 1 |
Trypanosoma cruzi | DNA polymerase kappa, putative | 0.002 | 0.0327 | 0.1208 |
Loa Loa (eye worm) | pigment dispersing factor receptor c | 0.0053 | 0.1351 | 0.1323 |
Giardia lamblia | Flap structure-specific endonuclease | 0.0028 | 0.0553 | 0.9579 |
Schistosoma mansoni | terminal deoxycytidyl transferase | 0.002 | 0.0327 | 0.0327 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.002 | 0.0327 | 0.1904 |
Plasmodium vivax | RNA helicase-1, putative | 0.0028 | 0.0564 | 0.7109 |
Trichomonas vaginalis | DEAD box ATP-dependent RNA helicase, putative | 0.0028 | 0.0564 | 0.2712 |
Echinococcus multilocularis | dna polymerase eta | 0.0047 | 0.1181 | 0.1153 |
Schistosoma mansoni | NADP-specific isocitrate dehydrogenase | 0.0017 | 0.021 | 0.021 |
Trypanosoma brucei | unspecified product | 0.002 | 0.0327 | 0.1904 |
Trypanosoma brucei | DNA polymerase IV, putative | 0.002 | 0.0327 | 0.1904 |
Brugia malayi | Doublecortin family protein | 0.0022 | 0.037 | 0.0481 |
Echinococcus granulosus | flap endonuclease 1 | 0.0028 | 0.0553 | 0.0523 |
Toxoplasma gondii | flap structure-specific endonuclease 1, putative | 0.0028 | 0.0553 | 0.3065 |
Trypanosoma brucei | isocitrate dehydrogenase, putative | 0.0017 | 0.021 | 0.0791 |
Trypanosoma cruzi | DNA polymerase kappa, putative | 0.002 | 0.0327 | 0.1208 |
Echinococcus multilocularis | eukaryotic initiation factor 4A III | 0.0028 | 0.0564 | 0.0533 |
Schistosoma mansoni | lipoxygenase | 0.0022 | 0.037 | 0.037 |
Entamoeba histolytica | hypothetical protein | 0.0038 | 0.0886 | 1 |
Echinococcus granulosus | lipoxygenase domain containing protein | 0.0022 | 0.037 | 0.0339 |
Schistosoma mansoni | blooms syndrome DNA helicase | 0.0038 | 0.088 | 0.088 |
Loa Loa (eye worm) | isocitrate dehydrogenase | 0.0017 | 0.021 | 0.0178 |
Brugia malayi | Corticotropin releasing factor receptor 2 precursor, putative | 0.0053 | 0.1351 | 0.1879 |
Trypanosoma cruzi | ATP-dependent DEAD/H DNA helicase recQ, putative | 0.0026 | 0.0492 | 0.2908 |
Brugia malayi | hypothetical protein | 0.0022 | 0.037 | 0.0481 |
Schistosoma mansoni | aldehyde dehydrogenase | 0.0067 | 0.1805 | 0.1805 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.002 | 0.0327 | 0.1904 |
Loa Loa (eye worm) | hypothetical protein | 0.0036 | 0.0823 | 0.0793 |
Trichomonas vaginalis | DNA helicase recq, putative | 0.0026 | 0.0492 | 0.1891 |
Echinococcus multilocularis | snurportin 1 | 0.0326 | 1 | 1 |
Toxoplasma gondii | ATP-dependent DNA helicase, RecQ family protein | 0.002 | 0.0308 | 0.1705 |
Toxoplasma gondii | eukaryotic initiation factor-4A, putative | 0.0028 | 0.0564 | 0.3125 |
Schistosoma mansoni | importin beta-1 | 0.0031 | 0.0647 | 0.0647 |
Echinococcus granulosus | aldehyde dehydrogenase mitochondrial | 0.0067 | 0.1805 | 0.1778 |
Trypanosoma cruzi | DNA polymerase eta, putative | 0.0047 | 0.1181 | 1 |
Echinococcus multilocularis | NADP dependent isocitrate dehydrogenase | 0.0017 | 0.021 | 0.0178 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.002 | 0.0327 | 0.1904 |
Giardia lamblia | Translation initiation factor eIF-4A, putative | 0.0028 | 0.0564 | 1 |
Entamoeba histolytica | deoxycytidyl transferase, putative | 0.002 | 0.0327 | 0.3691 |
Echinococcus multilocularis | dna polymerase kappa | 0.002 | 0.0327 | 0.0296 |
Schistosoma mansoni | ran | 0.0022 | 0.0392 | 0.0392 |
Echinococcus multilocularis | terminal deoxycytidyl transferase rev1 | 0.002 | 0.0327 | 0.0296 |
Brugia malayi | Flap endonuclease-1 | 0.0028 | 0.0553 | 0.0742 |
Echinococcus granulosus | lipoxygenase domain containing protein | 0.0022 | 0.037 | 0.0339 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.002 | 0.0327 | 0.1904 |
Schistosoma mansoni | DNA helicase recq5 | 0.002 | 0.0308 | 0.0308 |
Trypanosoma cruzi | DNA polymerase kappa, putative | 0.002 | 0.0327 | 0.1208 |
Echinococcus multilocularis | cadherin EGF LAG seven pass G type receptor | 0.0017 | 0.0209 | 0.0177 |
Brugia malayi | MH2 domain containing protein | 0.0126 | 0.3683 | 0.5201 |
Brugia malayi | latrophilin 2 splice variant baaae | 0.0036 | 0.0823 | 0.1126 |
Echinococcus multilocularis | Polycystic kidney disease protein | 0.0022 | 0.037 | 0.0339 |
Echinococcus granulosus | arachidonate 5 lipoxygenase | 0.0061 | 0.1612 | 0.1585 |
Loa Loa (eye worm) | hypothetical protein | 0.0022 | 0.037 | 0.0339 |
Echinococcus granulosus | ATP dependent DNA helicase Q5 | 0.002 | 0.0308 | 0.0276 |
Brugia malayi | Bloom's syndrome protein homolog | 0.0048 | 0.12 | 0.1664 |
Brugia malayi | Latrophilin receptor protein 2 | 0.0017 | 0.0209 | 0.0252 |
Schistosoma mansoni | hypothetical protein | 0.0038 | 0.0886 | 0.0886 |
Trypanosoma brucei | importin beta-1 subunit, putative | 0.0031 | 0.0647 | 0.4935 |
Leishmania major | aldehyde dehydrogenase, mitochondrial precursor | 0.0067 | 0.1805 | 0.989 |
Brugia malayi | eukaryotic initiation factor 4A | 0.0028 | 0.0564 | 0.0758 |
Loa Loa (eye worm) | latrophilin receptor protein 2 | 0.0017 | 0.0209 | 0.0177 |
Schistosoma mansoni | lipoxygenase | 0.0061 | 0.1612 | 0.1612 |
Trypanosoma brucei | DNA polymerase IV, putative | 0.002 | 0.0327 | 0.1904 |
Entamoeba histolytica | hypothetical protein | 0.0038 | 0.0886 | 1 |
Loa Loa (eye worm) | transcription factor SMAD2 | 0.0126 | 0.3683 | 0.3662 |
Brugia malayi | RNA, U transporter 1 | 0.0087 | 0.2429 | 0.3415 |
Echinococcus multilocularis | Basic leucine zipper (bZIP) transcription | 0.0038 | 0.0886 | 0.0857 |
Trypanosoma cruzi | Eukaryotic initiation factor 4A-1 | 0.0028 | 0.0564 | 0.3646 |
Brugia malayi | Ets-domain containing protein | 0.0077 | 0.2108 | 0.2957 |
Plasmodium falciparum | importin beta, putative | 0.0031 | 0.0647 | 0.5423 |
Brugia malayi | isocitrate dehydrogenase | 0.0017 | 0.021 | 0.0253 |
Loa Loa (eye worm) | hypothetical protein | 0.0146 | 0.4302 | 0.4283 |
Toxoplasma gondii | HEAT repeat-containing protein | 0.0031 | 0.0647 | 0.3584 |
Echinococcus granulosus | 3 hydroxyacyl coenzyme A dehydrogenase type 2 | 0.0068 | 0.1823 | 0.1796 |
Loa Loa (eye worm) | nucleolar RNA-associated protein alpha | 0.0326 | 1 | 1 |
Loa Loa (eye worm) | RecQ helicase | 0.0048 | 0.12 | 0.1172 |
Schistosoma mansoni | DEAD box ATP-dependent RNA helicase | 0.0028 | 0.0564 | 0.0564 |
Echinococcus multilocularis | arachidonate 5 lipoxygenase | 0.0061 | 0.1612 | 0.1585 |
Loa Loa (eye worm) | fli-1 protein | 0.0233 | 0.7051 | 0.7041 |
Schistosoma mansoni | hypothetical protein | 0.0017 | 0.0209 | 0.0209 |
Toxoplasma gondii | aldehyde dehydrogenase | 0.0067 | 0.1805 | 1 |
Echinococcus granulosus | Polycystic kidney disease protein | 0.0022 | 0.037 | 0.0339 |
Schistosoma mansoni | flap endonuclease-1 | 0.0025 | 0.0469 | 0.0469 |
Schistosoma mansoni | 3-hydroxyacyl-CoA dehydrogenase | 0.0068 | 0.1823 | 0.1823 |
Schistosoma mansoni | hypothetical protein | 0.0017 | 0.0209 | 0.0209 |
Brugia malayi | hypothetical protein | 0.0038 | 0.0886 | 0.1217 |
Schistosoma mansoni | ets-related | 0.0011 | 0.0032 | 0.0032 |
Echinococcus granulosus | eukaryotic initiation factor 4A | 0.0028 | 0.0564 | 0.0533 |
Trypanosoma cruzi | GTP-binding nuclear protein rtb2, putative | 0.0022 | 0.0392 | 0.1872 |
Schistosoma mansoni | rab geranylgeranyl transferase alpha subunit | 0.002 | 0.0327 | 0.0327 |
Loa Loa (eye worm) | hypothetical protein | 0.0031 | 0.0647 | 0.0617 |
Echinococcus granulosus | cadherin EGF LAG seven pass G type receptor | 0.0017 | 0.0209 | 0.0177 |
Brugia malayi | 3-hydroxyacyl-CoA dehydrogenase type II | 0.0068 | 0.1823 | 0.2551 |
Loa Loa (eye worm) | hypothetical protein | 0.0066 | 0.1756 | 0.1729 |
Echinococcus granulosus | diuretic hormone 44 receptor GPRdih2 | 0.0017 | 0.0209 | 0.0177 |
Plasmodium vivax | ADP-dependent DNA helicase RecQ, putative | 0.0032 | 0.0708 | 1 |
Loa Loa (eye worm) | flap endonuclease-1 | 0.0028 | 0.0553 | 0.0523 |
Loa Loa (eye worm) | MH2 domain-containing protein | 0.0126 | 0.3683 | 0.3662 |
Loa Loa (eye worm) | doublecortin family protein | 0.0022 | 0.037 | 0.0339 |
Mycobacterium tuberculosis | Possible DNA-damage-inducible protein P DinP (DNA polymerase V) (pol IV 2) (DNA nucleotidyltransferase (DNA-directed)) | 0.002 | 0.0327 | 0.0727 |
Echinococcus granulosus | eukaryotic initiation factor 4A III | 0.0028 | 0.0564 | 0.0533 |
Trypanosoma cruzi | DNA polymerase eta, putative | 0.0033 | 0.0735 | 0.5406 |
Schistosoma mansoni | elf1 | 0.0011 | 0.0032 | 0.0032 |
Loa Loa (eye worm) | D-ets-4 DNA binding domain-containing protein | 0.0077 | 0.2108 | 0.2082 |
Mycobacterium tuberculosis | Conserved hypothetical protein | 0.002 | 0.0327 | 0.0727 |
Trypanosoma cruzi | importin beta-1 subunit, putative | 0.0025 | 0.0464 | 0.2617 |
Schistosoma mansoni | hypothetical protein | 0.0036 | 0.0823 | 0.0823 |
Brugia malayi | Isocitrate dehydrogenase | 0.0017 | 0.021 | 0.0253 |
Treponema pallidum | ATP-dependent RNA helicase | 0.0028 | 0.0564 | 0.5 |
Loa Loa (eye worm) | ATP-dependent DNA helicase | 0.002 | 0.0308 | 0.0276 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.002 | 0.0327 | 0.1904 |
Loa Loa (eye worm) | hypothetical protein | 0.016 | 0.4746 | 0.4729 |
Schistosoma mansoni | ets | 0.0011 | 0.0032 | 0.0032 |
Onchocerca volvulus | 0.016 | 0.4746 | 1 | |
Giardia lamblia | GTP-binding nuclear protein RAN/TC4 | 0.0022 | 0.0392 | 0.3275 |
Mycobacterium tuberculosis | Probable aldehyde dehydrogenase | 0.0067 | 0.1805 | 0.989 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.002 | 0.0327 | 0.1904 |
Leishmania major | flap endonuclease-1 (FEN-1), putative | 0.0028 | 0.0553 | 0.2129 |
Schistosoma mansoni | loxhd1 | 0.0022 | 0.037 | 0.037 |
Plasmodium falciparum | flap endonuclease 1 | 0.0028 | 0.0553 | 0.4261 |
Mycobacterium ulcerans | aldehyde dehydrogenase | 0.0067 | 0.1805 | 0.9881 |
Trypanosoma cruzi | GTP-binding nuclear protein rtb2, putative | 0.0022 | 0.0392 | 0.1872 |
Trichomonas vaginalis | importin beta-1, putative | 0.0025 | 0.0464 | 0.1567 |
Schistosoma mansoni | polyomavirus enhancer activator 3 pea3 | 0.0011 | 0.0032 | 0.0032 |
Toxoplasma gondii | ImpB/MucB/SamB family protein | 0.0033 | 0.0735 | 0.4072 |
Schistosoma mansoni | rab6-interacting | 0.0022 | 0.037 | 0.037 |
Toxoplasma gondii | ATP-dependent DNA helicase, RecQ family protein | 0.0032 | 0.0696 | 0.3856 |
Loa Loa (eye worm) | 3-hydroxyacyl-CoA dehydrogenase type II | 0.0059 | 0.1552 | 0.1525 |
Entamoeba histolytica | DEAD/DEAH box helicase, putative | 0.0028 | 0.0564 | 0.6363 |
Trichomonas vaginalis | flap endonuclease-1, putative | 0.0028 | 0.0553 | 0.2589 |
Entamoeba histolytica | hypothetical protein | 0.0038 | 0.0886 | 1 |
Trypanosoma brucei | importin beta-1 subunit, putative | 0.0031 | 0.0647 | 0.4935 |
Plasmodium falciparum | ATP-dependent DNA helicase Q1 | 0.002 | 0.0308 | 0.1214 |
Schistosoma mansoni | hypothetical protein | 0.0326 | 1 | 1 |
Trypanosoma cruzi | Eukaryotic initiation factor 4A-1 | 0.0028 | 0.0564 | 0.3646 |
Loa Loa (eye worm) | hypothetical protein | 0.0053 | 0.1351 | 0.1323 |
Echinococcus granulosus | ATP dependent DNA helicase Q1 | 0.002 | 0.0308 | 0.0276 |
Plasmodium vivax | multidomain scavenger receptor, putative | 0.0022 | 0.037 | 0.3216 |
Leishmania major | DNA polymerase kappa, putative,DNA polymerase IV, putative | 0.002 | 0.0327 | 0.0727 |
Loa Loa (eye worm) | hypothetical protein | 0.0022 | 0.037 | 0.0339 |
Echinococcus multilocularis | importin subunit beta 1 | 0.0031 | 0.0647 | 0.0617 |
Mycobacterium tuberculosis | Probable cold-shock DeaD-box protein A homolog DeaD (ATP-dependent RNA helicase dead homolog) | 0.0028 | 0.0564 | 0.2196 |
Echinococcus multilocularis | flap endonuclease 1 | 0.0028 | 0.0553 | 0.0523 |
Entamoeba histolytica | Flap nuclease, putative | 0.0028 | 0.0553 | 0.6242 |
Trichomonas vaginalis | DEAD box ATP-dependent RNA helicase, putative | 0.0028 | 0.0564 | 0.2712 |
Toxoplasma gondii | GTP-binding nuclear protein ran/tc4 | 0.0022 | 0.0392 | 0.217 |
Brugia malayi | Ets-domain containing protein | 0.0077 | 0.2108 | 0.2957 |
Echinococcus multilocularis | diuretic hormone 44 receptor GPRdih2 | 0.0017 | 0.0209 | 0.0177 |
Echinococcus granulosus | GA binding protein alpha chain | 0.0077 | 0.2108 | 0.2082 |
Plasmodium vivax | importin-beta 2, putative | 0.0031 | 0.0647 | 0.8772 |
Echinococcus multilocularis | NADP dependent isocitrate dehydrogenase | 0.0017 | 0.021 | 0.0178 |
Trichomonas vaginalis | DEAD box ATP-dependent RNA helicase, putative | 0.0028 | 0.0564 | 0.2712 |
Trypanosoma brucei | GTP-binding nuclear protein rtb2, putative | 0.0022 | 0.0392 | 0.2515 |
Leishmania major | importin beta-1 subunit, putative | 0.0025 | 0.0464 | 0.1576 |
Trichomonas vaginalis | Importin beta-1 subunit, putative | 0.0025 | 0.0464 | 0.1567 |
Giardia lamblia | DINP protein human, muc B family | 0.002 | 0.0327 | 0.076 |
Brugia malayi | Calcitonin receptor-like protein seb-1 | 0.0053 | 0.1351 | 0.1879 |
Brugia malayi | GTP-binding nuclear protein RAN/TC4 | 0.0022 | 0.0392 | 0.0512 |
Echinococcus granulosus | GPCR family 2 | 0.0017 | 0.0209 | 0.0177 |
Echinococcus granulosus | importin subunit beta 1 | 0.0031 | 0.0647 | 0.0617 |
Echinococcus multilocularis | aldehyde dehydrogenase, mitochondrial | 0.0067 | 0.1805 | 0.1778 |
Plasmodium falciparum | GTP-binding nuclear protein RAN/TC4 | 0.0022 | 0.0392 | 0.2256 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.002 | 0.0327 | 0.1904 |
Echinococcus granulosus | dna polymerase kappa | 0.002 | 0.0327 | 0.0296 |
Echinococcus granulosus | GTP binding nuclear protein Ran | 0.0022 | 0.0392 | 0.036 |
Leishmania major | DNA polymerase eta, putative | 0.0047 | 0.1181 | 0.6023 |
Brugia malayi | hypothetical protein | 0.016 | 0.4746 | 0.6716 |
Trypanosoma brucei | ATP-dependent DEAD/H DNA helicase recQ, putative | 0.0026 | 0.0492 | 0.3469 |
Activity type | Activity value | Assay description | Source | Reference |
---|---|---|---|---|
Potency (binding) | = 28.1838 um | PUBCHEM_BIOASSAY: qHTS Assay for Identification of Novel General Anesthetics. In this assay, a GABAergic mimetic model system, apoferritin and a profluorescent 1-aminoanthracene ligand (1-AMA), was used to construct a competitive binding assay for identification of novel general anesthetics (Class of assay: confirmatory) [Related pubchem assays: 2385 (Probe Development Summary for Identification of Novel General Anesthetics), 2323 (Validation apoferritin assay run on SigmaAldrich LOPAC1280 collection)] | ChEMBL. | No reference |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.