Detailed information for compound 1362638

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 498.565 | Formula: C28H34O8
  • H donors: 0 H acceptors: 3 LogP: 3.5 Rotable bonds: 3
    Rule of 5 violations (Lipinski): 1
  • SMILES: CC(=O)OC1CC2C(C)(C)C(=O)C3C([C@@]2(C2[C@]1(C)C14OC1C(=O)OC([C@@]4(CC2)C)c1ccoc1)C)O3
  • InChi: 1S/C28H34O8/c1-13(29)33-17-11-16-24(2,3)19(30)18-21(34-18)26(16,5)15-7-9-25(4)20(14-8-10-32-12-14)35-23(31)22-28(25,36-22)27(15,17)6/h8,10,12,15-18,20-22H,7,9,11H2,1-6H3/t15?,16?,17?,18?,20?,21?,22?,25-,26+,27-,28?/m0/s1
  • InChiKey: AZGNIKZHFDJEPU-QJSJFKTCSA-N  


Substructure search Similarity search

Network

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

Species Target name Source Bibliographic reference
Mus musculus RAR-related orphan receptor gamma Starlite/ChEMBL No references

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Trichomonas vaginalis adenylate cyclase, putative 0.0012 0.0021 0.0045
Trypanosoma cruzi glyceraldehyde 3-phosphate dehydrogenase, cytosolic, putative 0.0407 0.234 0.6486
Echinococcus multilocularis microtubule associated protein 2 0.1362 0.7949 0.7949
Trypanosoma brucei adenosine transporter 2, putative 0.0043 0.02 0.0537
Trypanosoma brucei dihydrolipoamide dehydrogenase, point mutation 0.0016 0.0042 0.0099
Echinococcus multilocularis Polycystic kidney disease protein 0.0012 0.0021 0.0021
Trichomonas vaginalis chromobox protein, putative 0.0026 0.0103 0.0334
Loa Loa (eye worm) hypothetical protein 0.0248 0.1405 0.3899
Loa Loa (eye worm) hypothetical protein 0.0013 0.0023 0.0064
Mycobacterium leprae Probable lipase LipE 0.0035 0.0155 0.1192
Brugia malayi Unidentified vitellogenin-linked transcript protein 6, putative 0.0248 0.1405 0.3899
Brugia malayi Intermediate filament tail domain containing protein 0.0026 0.0102 0.0284
Loa Loa (eye worm) hypothetical protein 0.0248 0.1405 0.3899
Schistosoma mansoni amine GPCR 0.0248 0.1405 0.1768
Brugia malayi sodium-independent organic anion transporter family protein 0.0067 0.0344 0.0955
Toxoplasma gondii PHD-finger domain-containing protein 0.0018 0.0056 0.0137
Schistosoma mansoni jumonji domain containing protein 0.0048 0.0228 0.0287
Onchocerca volvulus 0.0248 0.1405 0.4372
Loa Loa (eye worm) hypothetical protein 0.0012 0.002 0.0057
Trypanosoma cruzi nucleoside transporter 1, putative 0.0043 0.02 0.0537
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0012 0.002 0.0057
Brugia malayi hypothetical protein 0.0248 0.1405 0.3899
Echinococcus multilocularis beta LACTamase domain containing family member 0.0035 0.0155 0.0155
Brugia malayi Cytochrome P450 family protein 0.0022 0.0076 0.0212
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.0012 0.002 0.002
Brugia malayi secreted modular calcium-binding protein 1 0.0046 0.0219 0.0607
Brugia malayi PXA domain containing protein 0.0019 0.0058 0.0161
Loa Loa (eye worm) hypothetical protein 0.0012 0.002 0.0057
Mycobacterium tuberculosis Probable NADH dehydrogenase Ndh 0.0105 0.0564 0.4377
Leishmania major ribokinase, putative 0.0071 0.0365 0.0997
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0035 0.0155 0.0431
Echinococcus granulosus neuropeptide receptor 0.0248 0.1405 0.1768
Loa Loa (eye worm) hypothetical protein 0.0067 0.0344 0.0955
Schistosoma mansoni glyceraldehyde-3-phosphate dehydrogenase (phosphorylating) 0.0407 0.234 0.2944
Toxoplasma gondii Kazal-type serine protease inhibitor domain-containing protein 0.0046 0.0219 0.0589
Loa Loa (eye worm) hypothetical protein 0.0019 0.0058 0.0161
Echinococcus granulosus g protein coupled receptor 0.0248 0.1405 0.1768
Mycobacterium ulcerans arylsulfatase AtsD 0.0017 0.0047 0.0143
Echinococcus multilocularis regulator of G protein signaling 3 0.0019 0.0058 0.0058
Echinococcus granulosus chromobox protein 1 0.0044 0.0205 0.0258
Brugia malayi A-kinase anchor protein 10, precursor 0.0019 0.0058 0.0161
Trypanosoma cruzi adenosine kinase, putative 0.0071 0.0365 0.0997
Brugia malayi Immunoglobulin I-set domain containing protein 0.0028 0.0114 0.0317
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0248 0.1405 0.1768
Trichomonas vaginalis conserved hypothetical protein 0.0017 0.0047 0.0139
Loa Loa (eye worm) hypothetical protein 0.0012 0.002 0.0057
Brugia malayi Glyceraldehyde 3-phosphate dehydrogenase 0.014 0.0773 0.2145
Echinococcus multilocularis transcription factor Dp 1 0.0039 0.0176 0.0176
Toxoplasma gondii histone lysine methyltransferase SET1 0.0055 0.0272 0.0739
Onchocerca volvulus 0.0248 0.1405 0.4372
Brugia malayi Pre-SET motif family protein 0.0436 0.251 0.6965
Echinococcus granulosus equilibrative nucleoside transporter 0.0246 0.1394 0.1754
Echinococcus granulosus Solute carrier organic anion transporter family 0.0067 0.0344 0.0433
Leishmania major glyceraldehyde-3-phosphate dehydrogenase-like protein 0.0267 0.1514 0.419
Mycobacterium leprae PROBABLE 6-PHOSPHOFRUCTOKINASE PFKA (PHOSPHOHEXOKINASE) (PHOSPHOFRUCTOKINASE) 0.0213 0.12 1
Loa Loa (eye worm) hypothetical protein 0.0067 0.0344 0.0955
Toxoplasma gondii CMGC kinase, MAPK family (ERK) MAPK-1 0.0062 0.031 0.0843
Trichomonas vaginalis conserved hypothetical protein 0.0017 0.0047 0.0139
Trypanosoma cruzi cytochrome P450, putative 0.0022 0.0076 0.0194
Echinococcus multilocularis equilibrative nucleoside transporter 3 0.0246 0.1394 0.1394
Loa Loa (eye worm) histone methyltransferase 0.0011 0.0013 0.0036
Trichomonas vaginalis CMGC family protein kinase 0.0062 0.031 0.1058
Loa Loa (eye worm) hypothetical protein 0.0063 0.0319 0.0886
Brugia malayi phosphofructokinase 0.0213 0.12 0.3328
Trypanosoma brucei purine nucleoside transporter 0.0043 0.02 0.0537
Plasmodium falciparum pyruvate kinase 0.0032 0.0139 0.0507
Trichomonas vaginalis phosphofructokinase, putative 0.0058 0.0287 0.0976
Trichomonas vaginalis pyruvate kinase, putative 0.0032 0.0139 0.0459
Schistosoma mansoni axis inhibition protein axin 0.0019 0.0058 0.0073
Giardia lamblia Glyceraldehyde 3-phosphate dehydrogenase 0.0267 0.1514 0.6406
Brugia malayi G-protein coupled receptor 0.0248 0.1405 0.3899
Echinococcus multilocularis rhodopsin orphan GPCR 0.0248 0.1405 0.1405
Echinococcus granulosus g protein coupled receptor 0.0248 0.1405 0.1768
Onchocerca volvulus 0.0035 0.0155 0.0427
Leishmania major adenosine kinase-like protein 0.0071 0.0365 0.0997
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0183 0.1024 0.3559
Schistosoma mansoni serine/threonine protein kinase 0.0062 0.031 0.039
Trypanosoma cruzi STE group serine/threonine-protein kinase, putative 0.0013 0.0024 0.0049
Trypanosoma cruzi adenosine kinase, putative 0.0071 0.0365 0.0997
Echinococcus granulosus bloom syndrome protein 0.0021 0.0073 0.0091
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0063 0.0318 0.0318
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0012 0.002 0.0057
Brugia malayi photoreceptor-specific nuclear receptor 0.0012 0.002 0.0057
Entamoeba histolytica phosphofructokinase, putative 0.0213 0.12 0.5095
Mycobacterium ulcerans pyruvate kinase 0.0032 0.0139 0.0536
Trichomonas vaginalis conserved hypothetical protein 0.0017 0.0047 0.0139
Schistosoma mansoni cpg binding protein 0.0029 0.0122 0.0153
Brugia malayi Probable G protein-coupled receptor kinase F19C6.1, putative 0.0019 0.0061 0.017
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.0012 0.002 0.0057
Trypanosoma cruzi Lanosterol 14-alpha demethylase 0.0011 0.0014 0.0021
Brugia malayi jmjC domain containing protein 0.006 0.03 0.0833
Trypanosoma cruzi nucleobase transporter, putative 0.0043 0.02 0.0537
Toxoplasma gondii ABC1 family protein 0.0035 0.0155 0.0414
Schistosoma mansoni coup transcription factor 0.0012 0.002 0.0026
Leishmania major protein kinase, putative 0.0013 0.0024 0.0049
Loa Loa (eye worm) G-protein coupled receptor 0.0248 0.1405 0.3899
Echinococcus multilocularis bloom syndrome protein 0.0021 0.0073 0.0073
Echinococcus granulosus axis inhibition protein axin 0.0019 0.0058 0.0073
Loa Loa (eye worm) hypothetical protein 0.0071 0.0365 0.1013
Trypanosoma brucei protein kinase, putative 0.0062 0.031 0.0843
Loa Loa (eye worm) hypothetical protein 0.0043 0.02 0.0554
Echinococcus granulosus neuropeptide FF receptor 2 0.0248 0.1405 0.1768
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0248 0.1405 0.1405
Loa Loa (eye worm) hypothetical protein 0.0071 0.0365 0.1013
Loa Loa (eye worm) RGS-3 protein 0.0019 0.0058 0.0161
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.0012 0.002 0.0057
Trypanosoma cruzi glyceraldehyde 3-phosphate dehydrogenase, putative 0.0407 0.234 0.6486
Echinococcus multilocularis g protein coupled receptor 0.0248 0.1405 0.1405
Echinococcus multilocularis ribokinase 0.0071 0.0365 0.0365
Plasmodium falciparum apurinic/apyrimidinic endonuclease Apn1, putative 0.0076 0.0394 0.1606
Mycobacterium ulcerans arylsulfatase, AslA 0.0017 0.0047 0.0143
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0063 0.0318 0.0399
Trypanosoma brucei trypanothione reductase 0.0046 0.0218 0.0588
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.007 0.0361 0.0454
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0012 0.002 0.0057
Brugia malayi AKH receptor 0.0248 0.1405 0.3899
Mycobacterium tuberculosis Conserved protein 0.0035 0.0155 0.1126
Mycobacterium leprae Probable fructose bisphosphate aldolase Fba 0.0089 0.0474 0.388
Trichomonas vaginalis regulator of G protein signaling 5, rgs5, putative 0.0019 0.0058 0.0176
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 8 0.0045 0.0211 0.0265
Echinococcus multilocularis PHD finger protein rhinoceros 0.0018 0.0056 0.0056
Mycobacterium leprae Probable adenosine kinase adk 0.0071 0.0365 0.2962
Brugia malayi Latrophilin receptor protein 2 0.0016 0.0042 0.0115
Echinococcus multilocularis ubiquitin specific protease 41 0.0045 0.0211 0.0211
Trichomonas vaginalis equilibrative nucleoside transporter, putative 0.0246 0.1394 0.4854
Trypanosoma cruzi nucleoside transporter-like, putative 0.0043 0.02 0.0537
Trypanosoma cruzi nucleoside transporter 1, putative 0.0043 0.02 0.0537
Brugia malayi Kazal-type serine protease inhibitor domain containing protein 0.0046 0.0219 0.0607
Loa Loa (eye worm) hypothetical protein 0.0012 0.002 0.0057
Toxoplasma gondii cytochrome p450 superfamily protein 0.0011 0.0014 0.0021
Onchocerca volvulus Pyruvate kinase homolog 0.0032 0.0139 0.0374
Brugia malayi hypothetical protein 0.0043 0.02 0.0554
Schistosoma mansoni steroid hormone receptor ad4bp 0.0012 0.002 0.0026
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0012 0.002 0.0057
Echinococcus granulosus intermediate filament protein 0.0026 0.0102 0.0129
Trypanosoma cruzi PAS-domain containing phosphoglycerate kinase, putative 0.0012 0.0021 0.0039
Loa Loa (eye worm) hypothetical protein 0.0248 0.1405 0.3899
Trichomonas vaginalis conserved hypothetical protein 0.0019 0.0058 0.0176
Onchocerca volvulus Ribokinase homolog 0.0071 0.0365 0.1089
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0248 0.1405 0.1768
Mycobacterium tuberculosis Probable oxidoreductase 0.0116 0.0632 0.4923
Leishmania major tagatose-6-phosphate kinase-like protein 0.0071 0.0365 0.0997
Trichomonas vaginalis conserved hypothetical protein 0.0019 0.0058 0.0176
Loa Loa (eye worm) cytoplasmic intermediate filament protein 0.0014 0.0031 0.0086
Echinococcus granulosus microtubule associated protein 2 0.1362 0.7949 1
Echinococcus multilocularis neuropeptide Y receptor 0.0248 0.1405 0.1405
Brugia malayi hypothetical protein 0.0019 0.0058 0.0161
Mycobacterium tuberculosis Probable endonuclease IV End (endodeoxyribonuclease IV) (apurinase) 0.0076 0.0394 0.3023
Trypanosoma brucei nucleobase/nucleoside transporter 8.1, putative 0.0043 0.02 0.0537
Trypanosoma brucei adenosine kinase, putative 0.0623 0.3604 1
Trypanosoma cruzi glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain, putative 0.0126 0.069 0.1898
Trypanosoma cruzi peptidyl-prolyl cis-trans isomerase 0.0032 0.0135 0.0356
Echinococcus multilocularis 0.0011 0.0014 0.0014
Loa Loa (eye worm) aryl Hydrocarbon receptor Associated protein family member 0.0012 0.0021 0.0058
Echinococcus granulosus g-protein coupled receptor 0.0248 0.1405 0.1768
Echinococcus granulosus serotonin receptor 0.0248 0.1405 0.1768
Trypanosoma brucei ATP-dependent 6-phosphofructokinase, glycosomal 0.0213 0.12 0.3316
Trichomonas vaginalis ribokinase, putative 0.0071 0.0365 0.1251
Brugia malayi putative neuropeptide receptor NPR1 0.0248 0.1405 0.3899
Echinococcus granulosus G protein coupled 5 hydroxytryptamine receptor 0.0248 0.1405 0.1768
Trypanosoma cruzi glyceraldehyde 3-phosphate dehydrogenase, putative 0.0407 0.234 0.6486
Loa Loa (eye worm) hypothetical protein 0.0019 0.0058 0.0161
Toxoplasma gondii pyruvate dehydrogenase complex subunit PDH-E3II 0.0016 0.0042 0.0099
Schistosoma mansoni adenosine kinase 0.0623 0.3604 0.4534
Mycobacterium tuberculosis Probable dehydrogenase 0.0105 0.0564 0.4377
Schistosoma mansoni nuclear hormone receptor 0.0012 0.002 0.0026
Echinococcus multilocularis neuropeptide s receptor 0.0695 0.4029 0.4029
Loa Loa (eye worm) hypoxia-induced factor 1 0.0146 0.0807 0.224
Mycobacterium tuberculosis Possible arylsulfatase AtsD (aryl-sulfate sulphohydrolase) (arylsulphatase) 0.0017 0.0047 0.0265
Trypanosoma cruzi ribokinase, putative 0.0071 0.0365 0.0997
Trypanosoma cruzi STE/STE11 serine/threonine-protein kinase, putative 0.0013 0.0024 0.0049
Trichomonas vaginalis ribokinase, putative 0.0071 0.0365 0.1251
Onchocerca volvulus 0.0028 0.0112 0.0291
Mycobacterium ulcerans hydrolase 0.0017 0.0047 0.0143
Plasmodium vivax hypothetical protein, conserved 0.0035 0.0155 0.0579
Brugia malayi nuclear hormone receptor 0.0012 0.002 0.0057
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0045 0.0211 0.0711
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.0012 0.002 0.0026
Echinococcus granulosus cpg binding protein 0.0029 0.0122 0.0153
Loa Loa (eye worm) cytochrome P450 family protein 0.0022 0.0076 0.0212
Mycobacterium ulcerans sulfatase 0.0017 0.0047 0.0143
Echinococcus multilocularis arachidonate 5 lipoxygenase 0.0074 0.0383 0.0383
Echinococcus multilocularis somatostatin receptor 0.0248 0.1405 0.1405
Trichomonas vaginalis adenylate and guanylate cyclases, putative 0.0012 0.0021 0.0045
Echinococcus multilocularis rhodopsin orphan GPCR 0.0248 0.1405 0.1405
Echinococcus granulosus dro:myosuppressin receptor 0.0248 0.1405 0.1768
Trichomonas vaginalis equilibrative nucleoside transporter, putative 0.0246 0.1394 0.4854
Echinococcus multilocularis mitogen activated protein kinase 0.0062 0.031 0.031
Brugia malayi regulator of G-protein signaling rgs-7 0.0019 0.0058 0.0161
Loa Loa (eye worm) hypothetical protein 0.0248 0.1405 0.3899
Brugia malayi Protein kinase domain containing protein 0.0029 0.0117 0.0326
Schistosoma mansoni regulator of G protein signaling 0.0019 0.0058 0.0073
Trichomonas vaginalis glyceraldehyde 3-phosphate dehydrogenase, putative 0.0267 0.1515 0.5278
Mycobacterium tuberculosis Conserved protein 0.0035 0.0155 0.1126
Entamoeba histolytica hypothetical protein 0.0019 0.0058 0.0185
Plasmodium falciparum phd finger protein, putative 0.0018 0.0056 0.015
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0015 0.0038 0.0048
Schistosoma mansoni hypothetical protein 0.0016 0.0042 0.0052
Echinococcus multilocularis thioredoxin glutathione reductase 0.0046 0.0218 0.0218
Echinococcus multilocularis neuropeptide Y receptor 0.0248 0.1405 0.1405
Chlamydia trachomatis dihydrolipoyl dehydrogenase 0.0016 0.0042 0.0092
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0248 0.1405 0.1768
Schistosoma mansoni thyrotropin-releasing hormone receptor 0.0248 0.1405 0.1768
Trypanosoma brucei glyceraldehyde 3-phosphate dehydrogenase, cytosolic 0.0407 0.234 0.6486
Trichomonas vaginalis equilibrative nucleoside transporter, putative 0.0043 0.02 0.0672
Echinococcus granulosus aldehyde dehydrogenase mitochondrial 0.0059 0.0295 0.0371
Giardia lamblia Hypothetical protein 0.0017 0.0047 0.0023
Mycobacterium leprae Probable glyceraldehyde 3-phosphate dehydrogenase Gap (GAPDH) 0.0141 0.0775 0.6415
Echinococcus multilocularis FTZ F1 alpha 0.0012 0.002 0.002
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0183 0.1024 0.3559
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0013 0.0028 0.007
Schistosoma mansoni thyroid hormone receptor 0.0012 0.002 0.0026
Giardia lamblia Pyruvate kinase 0.0032 0.0139 0.0421
Mycobacterium ulcerans arylsulfatase AtsB 0.0017 0.0047 0.0143
Schistosoma mansoni chromobox protein 0.0044 0.0205 0.0258
Echinococcus granulosus mitogen activated protein kinase 0.0062 0.031 0.039
Echinococcus granulosus FTZ F1 alpha 0.0012 0.002 0.0026
Loa Loa (eye worm) hypothetical protein 0.0248 0.1405 0.3899
Onchocerca volvulus 0.0248 0.1405 0.4372
Echinococcus multilocularis glyceraldehyde 3 phosphate dehydrogenase 0.0407 0.234 0.234
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0012 0.002 0.002
Echinococcus granulosus hypothetical protein 0.0248 0.1405 0.1768
Loa Loa (eye worm) hypothetical protein 0.0031 0.0133 0.0368
Trichomonas vaginalis glyceraldehyde 3-phosphate dehydrogenase, putative 0.0267 0.1515 0.5278
Trichomonas vaginalis adenylate and guanylate cyclases, putative 0.0012 0.0021 0.0045
Trypanosoma cruzi cytochrome p450-like protein, putative 0.0011 0.0014 0.0021
Trypanosoma brucei unspecified product 0.0043 0.02 0.0537
Brugia malayi Ribokinase 0.0071 0.0365 0.1013
Brugia malayi Nucleoside transporter family protein 0.0246 0.1394 0.3868
Echinococcus multilocularis equilibrative nucleoside transporter 3 0.0203 0.1143 0.1143
Mycobacterium tuberculosis Putative ferredoxin reductase 0.0105 0.0564 0.4377
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0012 0.002 0.0026
Schistosoma mansoni jumonji/arid domain-containing protein 0.0024 0.0088 0.0111
Brugia malayi PXA domain containing protein 0.0019 0.0058 0.0161
Echinococcus granulosus biogenic amine 5HT receptor 0.0248 0.1405 0.1768
Toxoplasma gondii kinase, pfkB family protein 0.0623 0.3604 1
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0248 0.1405 0.1768
Brugia malayi MH2 domain containing protein 0.0086 0.0456 0.1265
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.0012 0.002 0.0057
Toxoplasma gondii kinase, pfkB family protein 0.0071 0.0365 0.0997
Loa Loa (eye worm) melatonin receptor type 1A 0.0248 0.1405 0.3899
Schistosoma mansoni 6-phosphofructokinase 0.0213 0.12 0.1509
Loa Loa (eye worm) hypothetical protein 0.0248 0.1405 0.3899
Schistosoma mansoni cytochrome P450 0.0011 0.0014 0.0018
Loa Loa (eye worm) hypothetical protein 0.002 0.0066 0.0182
Trichomonas vaginalis conserved hypothetical protein 0.0045 0.0211 0.0711
Toxoplasma gondii transporter, major facilitator family protein 0.0067 0.0344 0.0938
Schistosoma mansoni hypothetical protein 0.0034 0.0149 0.0188
Schistosoma mansoni microtubule-associated protein tau 0.1362 0.7949 1
Schistosoma mansoni aldehyde dehydrogenase 0.0059 0.0295 0.0371
Plasmodium falciparum glutathione reductase 0.0046 0.0218 0.085
Loa Loa (eye worm) hypothetical protein 0.0248 0.1405 0.3899
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0062 0.031 0.0843
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.0012 0.002 0.0057
Echinococcus multilocularis ankyrin repeat and death domain containing protein 0.0028 0.0114 0.0114
Echinococcus granulosus tm gpcr rhodopsin 0.0248 0.1405 0.1768
Trypanosoma cruzi STE group serine/threonine-protein kinase, putative 0.0013 0.0024 0.0049
Trichomonas vaginalis DNA helicase recq, putative 0.0021 0.0073 0.0227
Echinococcus multilocularis A kinase anchor protein 10, mitochondrial 0.0019 0.0058 0.0058
Loa Loa (eye worm) hypothetical protein 0.0248 0.1405 0.3899
Brugia malayi Bloom's syndrome protein homolog 0.0021 0.0073 0.0201
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0183 0.1024 0.3559
Echinococcus multilocularis pyruvate kinase 0.0017 0.0046 0.0046
Loa Loa (eye worm) AGC/GRK/BARK protein kinase 0.0019 0.0061 0.017
Onchocerca volvulus 0.0248 0.1405 0.4372
Brugia malayi ORL1-like opioid receptor 0.0248 0.1405 0.3899
Loa Loa (eye worm) hypothetical protein 0.0248 0.1405 0.3899
Echinococcus granulosus lipoxygenase domain containing protein 0.0012 0.0021 0.0027
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0012 0.002 0.002
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0035 0.0155 0.0196
Brugia malayi nuclear receptor NHR-88 0.0012 0.002 0.0057
Echinococcus granulosus beta-adrenergic receptor kinase 0.0019 0.0061 0.0077
Echinococcus granulosus transcription factor Dp 1 0.0039 0.0176 0.0221
Loa Loa (eye worm) hypothetical protein 0.0248 0.1405 0.3899
Mycobacterium tuberculosis Conserved protein 0.0035 0.0155 0.1126
Brugia malayi G-protein-linked acetylcholine receptor protein 2, putative 0.0248 0.1405 0.3899
Echinococcus multilocularis agrin 0.0046 0.0219 0.0219
Schistosoma mansoni rab6-interacting 0.0012 0.0021 0.0027
Brugia malayi Bromodomain containing protein 0.0018 0.0056 0.0155
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0016 0.0042 0.0099
Loa Loa (eye worm) hypothetical protein 0.0267 0.1515 0.4204
Loa Loa (eye worm) pyruvate kinase 0.0032 0.0139 0.0385
Loa Loa (eye worm) hypothetical protein 0.0019 0.0058 0.0161
Loa Loa (eye worm) 5-hydroxytryptamine 2C receptor 0.0248 0.1405 0.3899
Schistosoma mansoni serine/threonine protein kinase 0.0019 0.0061 0.0077
Echinococcus granulosus regulator of G protein signaling 3 0.0019 0.0058 0.0073
Schistosoma mansoni loxhd1 0.0012 0.0021 0.0027
Echinococcus multilocularis pyruvate kinase 0.0017 0.0046 0.0046
Loa Loa (eye worm) hypothetical protein 0.0248 0.1405 0.3899
Onchocerca volvulus 0.0035 0.0155 0.0427
Leishmania major cytochrome p450-like protein 0.0022 0.0076 0.0194
Echinococcus multilocularis mixed lineage leukemia protein mll 0.0009 0.0003 0.0003
Loa Loa (eye worm) G-protein coupled receptor 0.0248 0.1405 0.3899
Echinococcus multilocularis sex peptide receptor 0.0248 0.1405 0.1405
Loa Loa (eye worm) hypothetical protein 0.0622 0.36 0.9987
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0248 0.1405 0.1405
Trichomonas vaginalis glyceraldehyde 3-phosphate dehydrogenase, putative 0.0407 0.234 0.8166
Onchocerca volvulus 0.0248 0.1405 0.4372
Mycobacterium tuberculosis Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras 0.0116 0.0632 0.4923
Echinococcus granulosus peregrin 0.0018 0.0056 0.007
Trypanosoma brucei adenosine transporter, putative 0.0043 0.02 0.0537
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0016 0.0042 0.0099
Schistosoma mansoni ubiquitin-specific peptidase 8 (C19 family) 0.0045 0.0211 0.0265
Schistosoma mansoni polycystin 1-related 0.0012 0.0021 0.0027
Trypanosoma brucei ATP-dependent DEAD/H DNA helicase recQ, putative 0.0011 0.0015 0.0023
Trichomonas vaginalis equilibrative nucleoside transporter, putative 0.0043 0.02 0.0672
Loa Loa (eye worm) hypothetical protein 0.0034 0.0149 0.0415
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0075 0.0391 0.0391
Brugia malayi Adenosine kinase-like 0.0623 0.3604 1
Schistosoma mansoni glyceraldehyde-3-phosphate dehydrogenase (phosphorylating) 0.0407 0.234 0.2944
Echinococcus granulosus 7TM GPCR rhodopsin 0.0248 0.1405 0.1768
Loa Loa (eye worm) glyceraldehyde 3-phosphate dehydrogenase 0.0267 0.1515 0.4204
Echinococcus multilocularis G protein coupled receptor 139 0.0248 0.1405 0.1405
Echinococcus granulosus agrin 0.0046 0.0219 0.0275
Echinococcus granulosus pyruvate kinase 0.0032 0.0139 0.0175
Brugia malayi Tyrosyl-DNA phosphodiesterase family protein 0.0067 0.0341 0.0946
Onchocerca volvulus Equilibrative nucleoside transporter, putative homolog 0.0246 0.1394 0.4337
Schistosoma mansoni peptide (allatostatin)-like receptor 0.0248 0.1405 0.1768
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0016 0.0042 0.0099
Loa Loa (eye worm) hypothetical protein 0.0248 0.1405 0.3899
Entamoeba histolytica hypothetical protein 0.0019 0.0058 0.0185
Echinococcus granulosus 6 phosphofructokinase 0.0213 0.12 0.1509
Schistosoma mansoni adenosine kinase 0.0623 0.3604 0.4534
Loa Loa (eye worm) pyruvate kinase-PB 0.0023 0.0081 0.0226
Mycobacterium tuberculosis Probable soluble pyridine nucleotide transhydrogenase SthA (STH) (NAD(P)(+) transhydrogenase [B-specific]) (nicotinamide nucleot 0.0016 0.0042 0.0223
Loa Loa (eye worm) RecQ helicase 0.0021 0.0073 0.0201
Loa Loa (eye worm) hypothetical protein 0.0248 0.1405 0.3899
Echinococcus granulosus biogenic amine 5HT receptor 0.0248 0.1405 0.1768
Loa Loa (eye worm) hypothetical protein 0.0012 0.002 0.0057
Loa Loa (eye worm) hypothetical protein 0.0248 0.1405 0.3899
Trypanosoma cruzi glyceraldehyde 3-phosphate dehydrogenase, cytosolic, putative 0.0126 0.069 0.1898
Loa Loa (eye worm) hypothetical protein 0.0012 0.0021 0.0058
Brugia malayi Serotonin/octopamine receptor family protein 7 0.0248 0.1405 0.3899
Echinococcus multilocularis regulator of G protein signaling 3 0.0019 0.0058 0.0058
Leishmania major glyceraldehyde 3-phosphate dehydrogenase, glycosomal 0.0407 0.234 0.6486
Schistosoma mansoni neuropeptide receptor 0.0248 0.1405 0.1768
Mycobacterium ulcerans fructose-bisphosphate aldolase 0.0089 0.0474 0.1978
Trypanosoma cruzi nucleobase transporter, putative 0.0043 0.02 0.0537
Loa Loa (eye worm) hypothetical protein 0.0023 0.0081 0.0226
Loa Loa (eye worm) hypothetical protein 0.0067 0.0344 0.0955
Loa Loa (eye worm) hypothetical protein 0.0246 0.1394 0.3868
Trypanosoma cruzi ATP-dependent DEAD/H DNA helicase recQ, putative 0.0011 0.0015 0.0023
Echinococcus granulosus death domain containing protein 0.0028 0.0114 0.0144
Trichomonas vaginalis mercuric reductase, putative 0.0016 0.0042 0.012
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0012 0.002 0.0057
Echinococcus granulosus beta LACTamase domain containing family member 0.0035 0.0155 0.0196
Onchocerca volvulus Heterochromatin protein 1 homolog 0.0026 0.0103 0.0262
Mycobacterium ulcerans hypothetical protein 0.0035 0.0155 0.0608
Giardia lamblia Pyrophosphate-fructose 6-phosphate 1-phosphotransferase alpha subunit 0.0058 0.0287 0.1064
Echinococcus multilocularis cytoplasmic intermediate filament protein 0.0013 0.0023 0.0023
Echinococcus multilocularis lipoxygenase domain containing protein 0.0012 0.0021 0.0021
Brugia malayi putative neuropeptide receptor 0.0248 0.1405 0.3899
Trichomonas vaginalis conserved hypothetical protein 0.0019 0.0058 0.0176
Loa Loa (eye worm) hypothetical protein 0.0623 0.3604 1
Leishmania major pyruvate kinase 0.0032 0.0139 0.0368
Trichomonas vaginalis conserved hypothetical protein 0.0017 0.0047 0.0139
Entamoeba histolytica hypothetical protein 0.0075 0.0391 0.1617
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.0012 0.002 0.0026
Schistosoma mansoni agrin 0.0046 0.0219 0.0275
Echinococcus granulosus rhodopsin orphan GPCR 0.0248 0.1405 0.1768
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.0012 0.002 0.0026
Mycobacterium tuberculosis NADPH-dependent mycothiol reductase Mtr 0.0046 0.0218 0.1626
Onchocerca volvulus 0.0248 0.1405 0.4372
Brugia malayi Dopamine receptor 0.0248 0.1405 0.3899
Echinococcus granulosus Polycystic kidney disease protein 0.0012 0.0021 0.0027
Trypanosoma cruzi mitogen activated protein kinase 2, putative 0.0062 0.031 0.0843
Leishmania major tyrosyl-DNA phosphodiesterase 1 0.0067 0.0341 0.093
Schistosoma mansoni peptide (allatostatin/somatostatin)-like receptor 0.0248 0.1405 0.1768
Loa Loa (eye worm) TYRA-2 protein 0.0248 0.1405 0.3899
Trichomonas vaginalis phosphofructokinase, putative 0.0213 0.12 0.4173
Echinococcus granulosus Aryl hydrocarbon receptor nuclear 0.0012 0.0021 0.0026
Brugia malayi Regulator of G protein signaling domain containing protein 0.0019 0.0058 0.0161
Brugia malayi 6-phosphofructokinase 0.0213 0.12 0.3328
Echinococcus multilocularis aryl hydrocarbon receptor 0.0012 0.0021 0.0021
Echinococcus multilocularis neuropeptides capa receptor 0.0248 0.1405 0.1405
Trypanosoma cruzi cytochrome P450, putative 0.0022 0.0076 0.0194
Brugia malayi PHD-finger family protein 0.0018 0.0056 0.0155
Plasmodium falciparum ADP-dependent DNA helicase RecQ 0.0019 0.0058 0.0156
Trichomonas vaginalis guanylate cyclase, putative 0.0012 0.0021 0.0045
Loa Loa (eye worm) pigment dispersing factor receptor c 0.005 0.0242 0.0672
Plasmodium falciparum glyceraldehyde-3-phosphate dehydrogenase 0.0407 0.234 1
Trypanosoma cruzi glyceraldehyde 3-phosphate dehydrogenase, cytosolic, putative 0.0126 0.069 0.1898
Trichomonas vaginalis penicillin-binding protein, putative 0.0035 0.0155 0.0517
Echinococcus multilocularis expressed protein 0.0362 0.2077 0.2077
Echinococcus granulosus pyroglutamylated rfamide peptide receptor 0.0248 0.1405 0.1768
Brugia malayi Dopamine receptor protein 2 0.0248 0.1405 0.3899
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0248 0.1405 0.1768
Onchocerca volvulus 0.0497 0.2865 0.8982
Trypanosoma cruzi adenosine kinase, putative 0.0623 0.3604 1
Echinococcus granulosus expressed protein 0.0032 0.0139 0.0175
Trichomonas vaginalis conserved hypothetical protein 0.0017 0.0047 0.0139
Loa Loa (eye worm) CMGC/MAPK/ERK1 protein kinase 0.0062 0.031 0.086
Trichomonas vaginalis chromobox protein, putative 0.0026 0.0103 0.0334
Loa Loa (eye worm) 6-phosphofructokinase 0.0213 0.12 0.3328
Loa Loa (eye worm) hypothetical protein 0.0248 0.1405 0.3899
Onchocerca volvulus Equilibrative nucleoside transporter, putative homolog 0.0246 0.1394 0.4337
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0063 0.0319 0.0869
Echinococcus multilocularis pseudouridine metabolizing bifunctional protein 0.0071 0.0365 0.0365
Trichomonas vaginalis conserved hypothetical protein 0.0024 0.0092 0.0296
Echinococcus multilocularis Peptidase C19, ubiquitin carboxyl terminal hydrolase 2 0.0045 0.0211 0.0211
Schistosoma mansoni equilibrative nucleoside transporter 0.0043 0.02 0.0251
Brugia malayi hypothetical protein 0.0017 0.0047 0.0132
Trichomonas vaginalis conserved hypothetical protein 0.0017 0.0047 0.0139
Toxoplasma gondii pyruvate kinase PyK1 0.0032 0.0139 0.0368
Echinococcus granulosus orexin receptor type 2 0.0248 0.1405 0.1768
Trichomonas vaginalis conserved hypothetical protein 0.0017 0.0047 0.0139
Trypanosoma cruzi ATP-dependent 6-phosphofructokinase, glycosomal 0.0213 0.12 0.3316
Brugia malayi Cytochrome P450 family protein 0.0022 0.0076 0.0212
Echinococcus granulosus rhodopsin orphan GPCR 0.0248 0.1405 0.1768
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0075 0.0391 0.0492
Schistosoma mansoni biogenic amine (5HT) receptor 0.0248 0.1405 0.1768
Toxoplasma gondii thioredoxin reductase 0.0046 0.0218 0.0588
Loa Loa (eye worm) gonadotropin-releasing hormone receptor 2 0.0248 0.1405 0.3899
Plasmodium vivax glyceraldehyde-3-phosphate dehydrogenase, putative 0.0407 0.234 1
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0183 0.1024 0.3559
Loa Loa (eye worm) steroid hormone receptor 0.0012 0.002 0.0057
Schistosoma mansoni hypothetical protein 0.0248 0.1405 0.1768
Trypanosoma brucei nucleobase/nucleoside transporter 8.1, putative 0.0043 0.02 0.0537
Onchocerca volvulus 0.0012 0.0021 0.0003
Trichomonas vaginalis mucin-desulfating sulfatase, putative 0.0017 0.0047 0.0139
Onchocerca volvulus 0.0012 0.0021 0.0001
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0016 0.0042 0.0099
Trypanosoma brucei nucleobase/nucleoside transporter 8.1, putative 0.0043 0.02 0.0537
Schistosoma mansoni pyruvate kinase 0.0017 0.0046 0.0058
Loa Loa (eye worm) cytochrome P450 0.0011 0.0014 0.0039
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.006 0.0302 0.038
Mycobacterium leprae DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE 0.0116 0.0632 0.5215
Loa Loa (eye worm) hypothetical protein 0.0248 0.1405 0.3899
Trichomonas vaginalis rotamase, putative 0.0032 0.0139 0.046
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.0012 0.002 0.0057
Trichomonas vaginalis DNA helicase recq1, putative 0.0021 0.0073 0.0227
Loa Loa (eye worm) hypothetical protein 0.0248 0.1405 0.3899
Brugia malayi hypothetical protein 0.0246 0.1394 0.3868
Mycobacterium tuberculosis Probable conserved lipoprotein 0.0035 0.0155 0.1126
Echinococcus granulosus follistatin 0.0046 0.0219 0.0275
Trichomonas vaginalis conserved hypothetical protein 0.0017 0.0047 0.0139
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.0035 0.0155 0.1126
Entamoeba histolytica phosphofructokinase, putative 0.0213 0.12 0.5095
Onchocerca volvulus 0.0067 0.0344 0.1022
Echinococcus granulosus dihydrolipoamide dehydrogenase 0.0016 0.0042 0.0053
Leishmania major nucleoside transporter 1, putative 0.0043 0.02 0.0537
Brugia malayi beta-lactamase 0.0035 0.0155 0.0431
Trypanosoma cruzi tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0067 0.0341 0.093
Trypanosoma cruzi Lanosterol 14-alpha demethylase 0.0011 0.0014 0.0021
Wolbachia endosymbiont of Brugia malayi dihydrolipoamide dehydrogenase E3 component 0.0016 0.0042 0.0152
Onchocerca volvulus 0.0552 0.3188 1
Echinococcus multilocularis G protein coupled 5 hydroxytryptamine receptor 0.0248 0.1405 0.1405
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0248 0.1405 0.1768
Brugia malayi Nuclear hormone receptor family member nhr-41 0.0012 0.002 0.0057
Trichomonas vaginalis glyceraldehyde 3-phosphate dehydrogenase, putative 0.0407 0.234 0.8166
Schistosoma mansoni amine GPCR 0.0248 0.1405 0.1768
Schistosoma mansoni regulator of G protein signaling 17 19 20 (rgs17 19 20) 0.0019 0.0058 0.0073
Loa Loa (eye worm) hypothetical protein 0.0012 0.0021 0.0059
Echinococcus multilocularis thyroid hormone receptor alpha 0.0012 0.002 0.002
Brugia malayi Nuclear hormone receptor-like 1 0.0012 0.002 0.0057
Trypanosoma cruzi trypanothione reductase, putative 0.0016 0.0042 0.0099
Schistosoma mansoni biogenic amine (octopamine/dopamine) receptor 0.0248 0.1405 0.1768
Schistosoma mansoni neuropeptide receptor 0.0248 0.1405 0.1768
Schistosoma mansoni regulator of G protein signaling 0.0019 0.0058 0.0073
Brugia malayi Pyruvate kinase, M2 isozyme 0.0032 0.0139 0.0385
Onchocerca volvulus Alhambra homolog 0.0018 0.0056 0.0112
Loa Loa (eye worm) hypothetical protein 0.0012 0.002 0.0057
Trichomonas vaginalis CMGC family protein kinase 0.0062 0.031 0.1058
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0248 0.1405 0.1768
Echinococcus granulosus mixed lineage leukemia protein mll 0.0009 0.0003 0.0004
Trypanosoma brucei nucleobase/nucleoside transporter 8.1 0.0043 0.02 0.0537
Schistosoma mansoni adenoreceptor 0.0248 0.1405 0.1768
Echinococcus multilocularis dihydrolipoamide dehydrogenase 0.0016 0.0042 0.0042
Entamoeba histolytica tyrosyl-DNA phosphodiesterase, putative 0.0067 0.0341 0.1403
Echinococcus granulosus Transcription factor JmjC domain containing protein 0.006 0.03 0.0378
Brugia malayi Calcitonin receptor-like protein seb-1 0.005 0.0242 0.0672
Echinococcus multilocularis axis inhibition protein axin 0.0019 0.0058 0.0058
Trypanosoma cruzi hypothetical protein, conserved 0.0035 0.0155 0.0414
Brugia malayi Hypothetical 29.7 kDa protein C05D11.5 in chromosome III 0.002 0.0066 0.0182
Trichomonas vaginalis ribokinase, putative 0.0071 0.0365 0.1251
Trichomonas vaginalis adenylate cyclase, type VII, putative 0.0012 0.0021 0.0045
Trichomonas vaginalis chromobox protein, putative 0.0044 0.0205 0.0691
Echinococcus granulosus lamin 0.0026 0.0102 0.0129
Giardia lamblia Hypothetical protein 0.0017 0.0047 0.0023
Loa Loa (eye worm) hypothetical protein 0.0035 0.0155 0.0431
Onchocerca volvulus Putative hydroxypyruvate isomerase 0.002 0.0066 0.0143
Mycobacterium ulcerans flavoprotein disulfide reductase 0.0016 0.0042 0.012
Wolbachia endosymbiont of Brugia malayi glyceraldehyde-3-phosphate dehydrogenase, GapA 0.0407 0.234 1
Brugia malayi sodium-independent organic anion transporter family protein 0.0067 0.0344 0.0955
Schistosoma mansoni hypothetical protein 0.0028 0.0114 0.0144
Trichomonas vaginalis equilibrative nucleoside transporter, putative 0.0246 0.1394 0.4854
Plasmodium vivax ADP-dependent DNA helicase RecQ, putative 0.0014 0.0032 0.0048
Loa Loa (eye worm) hypothetical protein 0.0067 0.0344 0.0955
Echinococcus granulosus cytochrome P450 2K1 0.0011 0.0014 0.0018
Onchocerca volvulus 0.0012 0.0021 0.0003
Schistosoma mansoni intermediate filament proteins 0.0026 0.0102 0.0129
Schistosoma mansoni hypothetical protein 0.0248 0.1405 0.1768
Echinococcus granulosus expressed protein 0.0362 0.2077 0.2613
Echinococcus multilocularis chromobox protein 1 0.0044 0.0205 0.0205
Echinococcus multilocularis pyruvate kinase 0.0032 0.0139 0.0139
Mycobacterium leprae PROBABLE NADH DEHYDROGENASE NDH 0.0105 0.0564 0.4636
Echinococcus multilocularis Solute carrier organic anion transporter family 0.0067 0.0344 0.0344
Echinococcus multilocularis neuropeptide FF receptor 2 0.0248 0.1405 0.1405
Brugia malayi intermediate filament protein 0.0026 0.0102 0.0284
Brugia malayi Uncoordinated protein 44 0.0028 0.0114 0.0317
Loa Loa (eye worm) hypothetical protein 0.0028 0.0114 0.0317
Loa Loa (eye worm) hypothetical protein 0.0248 0.1405 0.3899
Plasmodium falciparum thioredoxin reductase 0.0046 0.0218 0.085
Onchocerca volvulus 0.0248 0.1405 0.4372
Leishmania major 2-oxoglutarate dehydrogenase, e3 component, lipoamidedehydrogenase-like protein 0.0016 0.0042 0.0099
Brugia malayi DNA-(Apurinic or apyrimidinic site) lyase 0.0076 0.0394 0.1092
Brugia malayi Serotonin receptor 0.0248 0.1405 0.3899
Loa Loa (eye worm) kazal-type serine protease inhibitor domain-containing protein 0.0046 0.0219 0.0607
Echinococcus multilocularis RUN 0.0012 0.0021 0.0021
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0016 0.0042 0.0042
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0248 0.1405 0.1768
Leishmania major putative PfkB family sugar kinase 0.0071 0.0365 0.0997
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase domain containing protein 0.0045 0.0211 0.0843
Plasmodium falciparum pyruvate kinase 2 0.0017 0.0046 0.0108
Echinococcus granulosus chromobox protein 1 0.0044 0.0205 0.0258
Plasmodium vivax apurinic/apyrimidinic endonuclease Apn1, putative 0.0076 0.0394 0.1606
Echinococcus multilocularis lamin 0.0026 0.0102 0.0102
Loa Loa (eye worm) STAT protein 0.013 0.0712 0.1976
Brugia malayi neuropeptide F receptor 0.0248 0.1405 0.3899
Echinococcus multilocularis expressed protein 0.0032 0.0139 0.0139
Loa Loa (eye worm) jmjC domain-containing protein 0.0024 0.0088 0.0244
Trypanosoma cruzi glyceraldehyde 3-phosphate dehydrogenase, cytosolic, putative 0.0407 0.234 0.6486
Schistosoma mansoni opsin-like receptor 0.0248 0.1405 0.1768
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.0012 0.002 0.0026
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0035 0.0155 0.0431
Trichomonas vaginalis D-aminoacylase, putative 0.0035 0.0155 0.0517
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0063 0.0319 0.0319
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0013 0.0028 0.007
Echinococcus multilocularis pyruvate kinase 0.0017 0.0046 0.0046
Echinococcus granulosus jumonji domain containing protein 0.0025 0.0098 0.0123
Echinococcus granulosus pyruvate kinase 0.0017 0.0046 0.0058
Trypanosoma brucei dihydrolipoyl dehydrogenase 0.0016 0.0042 0.0099
Mycobacterium tuberculosis Adenosine kinase 0.0071 0.0365 0.2796
Trypanosoma cruzi PAS-domain containing phosphoglycerate kinase, putative 0.0012 0.0021 0.0039
Trichomonas vaginalis conserved hypothetical protein 0.0019 0.0058 0.0176
Schistosoma mansoni biogenic amine (5HT) receptor 0.0248 0.1405 0.1768
Loa Loa (eye worm) hypothetical protein 0.0076 0.0394 0.1092
Echinococcus multilocularis lipoxygenase domain containing protein 0.0012 0.0021 0.0021
Brugia malayi alpha keto acid dehydrogenase complex, E3 component, lipoamide dehydrogenase 0.0012 0.0017 0.0048
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0248 0.1405 0.1768
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0063 0.0319 0.0319
Echinococcus granulosus tyrosyl DNA phosphodiesterase 1 0.0067 0.0341 0.0429
Leishmania major pyruvate kinase 0.0032 0.0139 0.0368
Echinococcus multilocularis netrin receptor unc 5 0.0028 0.0114 0.0114
Onchocerca volvulus 0.0067 0.0344 0.1022
Mycobacterium leprae conserved hypothetical protein 0.002 0.0066 0.0435
Trypanosoma brucei ubiquitin carboxyl-terminal hydrolase, putative 0.0045 0.0211 0.0568
Trichomonas vaginalis rotamase, putative 0.0032 0.0135 0.0444
Echinococcus granulosus tm gpcr rhodopsin 0.0248 0.1405 0.1768
Loa Loa (eye worm) hypothetical protein 0.0035 0.0155 0.0431
Brugia malayi Pin1-type peptidyl-prolyl cis-trans isomerase, BmPin1 0.0032 0.0139 0.0386
Loa Loa (eye worm) hypothetical protein 0.0248 0.1405 0.3899
Echinococcus granulosus growth hormone secretagogue receptor type 1 0.0248 0.1405 0.1768
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0016 0.0042 0.0099
Brugia malayi STAT protein, DNA binding domain containing protein 0.013 0.0712 0.1976
Mycobacterium ulcerans putative regulatory protein 0.0035 0.0154 0.0601
Onchocerca volvulus Neuropeptide F receptor homolog 0.0248 0.1405 0.4372
Toxoplasma gondii glyceraldehyde-3-phosphate dehydrogenase GAPDH2 0.0407 0.234 0.6486
Brugia malayi chromobox protein homolog 3 0.0024 0.0092 0.0256
Echinococcus granulosus rhodopsin orphan GPCR 0.0248 0.1405 0.1768
Trypanosoma brucei tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0067 0.0341 0.093
Toxoplasma gondii Kazal-type serine protease inhibitor domain-containing protein 0.0046 0.0219 0.0589
Leishmania major acetoin dehydrogenase e3 component-like protein 0.0016 0.0042 0.0099
Leishmania major inosine-guanosine transporter;with=GeneDB:LinJ36_V3.2040 0.0043 0.02 0.0537
Mycobacterium ulcerans carbohydrate kinase CbhK 0.0071 0.0365 0.151
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0016 0.0042 0.0099
Mycobacterium ulcerans cytochrome P450 185A4 Cyp185A4 0.0022 0.0076 0.0267
Brugia malayi SPARC precursor 0.0046 0.0219 0.0607
Leishmania major cytochrome p450-like protein 0.0011 0.0014 0.0021
Brugia malayi G-protein coupled receptor 0.0248 0.1405 0.3899
Loa Loa (eye worm) hypothetical protein 0.005 0.0242 0.0672
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0012 0.002 0.0026
Loa Loa (eye worm) hypothetical protein 0.0024 0.0092 0.0256
Mycobacterium ulcerans dihydrolipoamide dehydrogenase, LpdB 0.0016 0.0042 0.012
Brugia malayi cytoplasmic intermediate filament protein 0.0014 0.0031 0.0086
Plasmodium vivax hypothetical protein, conserved 0.0018 0.0056 0.015
Loa Loa (eye worm) hypothetical protein 0.0158 0.0879 0.244
Leishmania major mitogen activated protein kinase 4, putative;with=GeneDB:LmxM19.1440 0.0062 0.031 0.0843
Mycobacterium tuberculosis Probable pyruvate kinase PykA 0.0032 0.0139 0.0994
Loa Loa (eye worm) hypothetical protein 0.0018 0.0056 0.0155
Schistosoma mansoni bromodomain-containing nuclear protein 1 brd1 0.0018 0.0056 0.007
Trichomonas vaginalis penicillin-binding protein, putative 0.0035 0.0155 0.0517
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.005 0.0242 0.0672
Schistosoma mansoni hypothetical protein 0.0248 0.1405 0.1768
Echinococcus granulosus tachykinin peptides receptor 99D 0.0248 0.1405 0.1768
Echinococcus multilocularis organic anion transporting polypeptide 30B 0.0067 0.0344 0.0344
Loa Loa (eye worm) tyrosyl-DNA phosphodiesterase 0.0067 0.0341 0.0946
Onchocerca volvulus 0.0035 0.0155 0.0427
Brugia malayi Nuclear hormone receptor family member nhr-49 0.0012 0.002 0.0057
Loa Loa (eye worm) hypothetical protein 0.0035 0.0155 0.0431
Loa Loa (eye worm) pyruvate kinase 0.0032 0.0139 0.0385
Echinococcus granulosus Ankyrin 0.0028 0.0116 0.0145
Loa Loa (eye worm) jmjC domain-containing protein 0.0038 0.017 0.0472
Brugia malayi Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain containing protein 0.0012 0.0017 0.0048
Trichomonas vaginalis conserved hypothetical protein 0.0017 0.005 0.0149
Onchocerca volvulus GPI ethanolamine phosphate transferase 1 homolog 0.0017 0.0047 0.0086
Trichomonas vaginalis equilibrative nucleoside transporter, putative 0.0246 0.1394 0.4854
Chlamydia trachomatis fructose-6-phosphate phosphotransferase 0.0058 0.0287 0.1146
Trichomonas vaginalis conserved hypothetical protein 0.0012 0.0021 0.0045
Chlamydia trachomatis glyceraldehyde-3-phosphate dehydrogenase 0.0407 0.234 1
Trichomonas vaginalis conserved hypothetical protein 0.0017 0.0047 0.0139
Plasmodium falciparum thioredoxin reductase 0.0016 0.0042 0.009
Onchocerca volvulus 0.0248 0.1405 0.4372
Trypanosoma cruzi glyceraldehyde 3-phosphate dehydrogenase, putative 0.0407 0.234 0.6486
Toxoplasma gondii NADPH-glutathione reductase 0.0016 0.0042 0.0099
Echinococcus multilocularis neuropeptides capa receptor 0.0248 0.1405 0.1405
Trichomonas vaginalis phosphofructokinase, putative 0.0213 0.12 0.4173
Schistosoma mansoni aryl hydrocarbon receptor 0.0047 0.0226 0.0284
Onchocerca volvulus 0.0248 0.1405 0.4372
Schistosoma mansoni biogenic amine receptor 0.0248 0.1405 0.1768
Echinococcus granulosus ubiquitin specific protease 41 0.0045 0.0211 0.0265
Echinococcus granulosus alpha 1A adrenergic receptor 0.0248 0.1405 0.1768
Onchocerca volvulus 0.0019 0.0061 0.0129
Echinococcus granulosus tumor protein p63 0.1009 0.5875 0.7391
Brugia malayi hypothetical protein 0.0019 0.0058 0.0161
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0013 0.0028 0.007
Loa Loa (eye worm) hypothetical protein 0.0028 0.0116 0.0321
Brugia malayi Dopamine receptor protein 1, putative (partial) 0.0248 0.1405 0.3899
Loa Loa (eye worm) Pin1-type peptidyl-prolyl cis-trans isomerase 0.0032 0.0139 0.0386
Loa Loa (eye worm) transcription factor SMAD2 0.0086 0.0456 0.1265
Trichomonas vaginalis esterase, putative 0.0035 0.0155 0.0517
Echinococcus multilocularis neuropeptide receptor 0.0248 0.1405 0.1405
Echinococcus granulosus pyruvate kinase 0.0017 0.0046 0.0058
Schistosoma mansoni alpha-1 adrenergic receptor 0.0248 0.1405 0.1768
Echinococcus granulosus neuropeptide receptor A26 0.0695 0.4029 0.5068
Trichomonas vaginalis phosphofructokinase, putative 0.0213 0.12 0.4173
Schistosoma mansoni retinoic acid receptor RXR 0.0012 0.002 0.0026
Loa Loa (eye worm) hypothetical protein 0.0017 0.0048 0.0132
Brugia malayi MAP kinase sur-1 0.0062 0.031 0.086
Mycobacterium ulcerans epimerase 0.002 0.0066 0.0222
Trichomonas vaginalis conserved hypothetical protein 0.0017 0.0047 0.0139
Schistosoma mansoni hypothetical protein 0.0018 0.0056 0.007
Echinococcus granulosus glyceraldehyde 3 phosphate dehydrogenase 0.0267 0.1515 0.1906
Brugia malayi RE15519p 0.0248 0.1405 0.3899
Mycobacterium tuberculosis Probable reductase 0.0105 0.0564 0.4377
Echinococcus multilocularis g-protein coupled receptor 0.0248 0.1405 0.1405
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0063 0.0319 0.0402
Echinococcus multilocularis neuropeptide receptor A26 0.0695 0.4029 0.4029
Onchocerca volvulus 0.0248 0.1405 0.4372
Trypanosoma cruzi trypanothione reductase, putative 0.0046 0.0218 0.0588
Trypanosoma cruzi glyceraldehyde-3-phosphate dehydrogenase, putative 0.0267 0.1514 0.419
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.0183 0.1024 0.4341
Loa Loa (eye worm) hypothetical protein 0.0148 0.0816 0.2264
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0011 0.0013 0.0013
Onchocerca volvulus 0.0248 0.1405 0.4372
Leishmania major nucleobase transporter 0.0043 0.02 0.0537
Mycobacterium tuberculosis 6-phosphofructokinase PfkB (phosphohexokinase) (phosphofructokinase) 0.0071 0.0365 0.2796
Loa Loa (eye worm) hypothetical protein 0.0019 0.0058 0.0161
Echinococcus multilocularis Regulator of G protein signaling 20 0.0019 0.0058 0.0058
Mycobacterium ulcerans 6-phosphofructokinase 0.0213 0.12 0.5097
Brugia malayi neuropeptide F receptor 0.0248 0.1405 0.3899
Trypanosoma brucei mitogen activated protein kinase 4, putative 0.0062 0.031 0.0843
Mycobacterium tuberculosis Probable fructose-bisphosphate aldolase Fba 0.0089 0.0474 0.3663
Echinococcus multilocularis fmrfamide receptor 0.0248 0.1405 0.1405
Schistosoma mansoni regulator of G protein signaling 0.0019 0.0058 0.0073
Giardia lamblia Ubiquitin carboxyl-terminal hydrolase 4 0.0045 0.0211 0.0735
Loa Loa (eye worm) hypothetical protein 0.0046 0.0219 0.0607
Brugia malayi Serotonin receptor 0.0248 0.1405 0.3899
Schistosoma mansoni cpg binding protein 0.0029 0.0122 0.0153
Schistosoma mansoni follistatin 0.0046 0.0219 0.0275
Leishmania major cytochrome p450-like protein 0.0011 0.0014 0.0021
Chlamydia trachomatis endonuclease IV 0.0076 0.0394 0.1608
Brugia malayi Kazal-type serine protease inhibitor domain containing protein 0.0046 0.0219 0.0607
Schistosoma mansoni regulator of G protein signaling 0.0019 0.0058 0.0073
Loa Loa (eye worm) MH2 domain-containing protein 0.0086 0.0456 0.1265
Toxoplasma gondii peptidylprolyl isomerase 0.0032 0.0135 0.0356
Echinococcus multilocularis aldehyde dehydrogenase, mitochondrial 0.0059 0.0295 0.0295
Brugia malayi dihydrolipoyl dehydrogenase, mitochondrial precursor, putative 0.0016 0.0042 0.0117
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.0012 0.002 0.002
Brugia malayi Death domain containing protein 0.0028 0.0114 0.0317
Schistosoma mansoni RAR-like nuclear receptor 0.0012 0.002 0.0026
Schistosoma mansoni hypothetical protein 0.0016 0.0042 0.0052
Echinococcus multilocularis tumor protein p63 0.1009 0.5875 0.5875
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0035 0.0155 0.0196
Schistosoma mansoni regulator of G protein signaling 3 rgs3 0.0019 0.0058 0.0073
Echinococcus multilocularis fmrfamide receptor 0.0248 0.1405 0.1405
Toxoplasma gondii PHD-finger domain-containing protein 0.0018 0.0056 0.0137
Trypanosoma brucei adenosine transporter 2, putative 0.0043 0.02 0.0537
Brugia malayi Sulfatase family protein 0.0017 0.0047 0.0132
Loa Loa (eye worm) hypothetical protein 0.0248 0.1405 0.3899
Plasmodium falciparum ATP-dependent 6-phosphofructokinase 0.0058 0.0287 0.1145
Entamoeba histolytica nucleoside transporter, putative 0.0043 0.02 0.0795
Brugia malayi Regulator of G protein signaling domain containing protein 0.0019 0.0058 0.0161
Echinococcus multilocularis pyruvate kinase 0.0026 0.0099 0.0099
Trichomonas vaginalis phosphofructokinase, putative 0.0058 0.0287 0.0976
Trypanosoma cruzi MFS transporter, putative 0.0067 0.0344 0.0938
Loa Loa (eye worm) hypothetical protein 0.0248 0.1405 0.3899
Trypanosoma brucei peptidyl-prolyl cis-trans isomerase/rotamase, putative 0.0032 0.0135 0.0356
Trypanosoma brucei unspecified product 0.0043 0.02 0.0537
Echinococcus granulosus retinoic acid receptor rxr beta a 0.0012 0.002 0.0026
Leishmania major peptidyl-prolyl cis-trans isomerase/rotamase, putative,PPIase, putative 0.0032 0.0135 0.0356
Mycobacterium tuberculosis Possible penicillin-binding protein 0.0225 0.127 1
Trichomonas vaginalis CMGC family protein kinase 0.0062 0.031 0.1058
Echinococcus multilocularis mitogen activated protein kinase 3 0.0062 0.031 0.031
Trypanosoma brucei pyruvate kinase 1, putative 0.0032 0.0139 0.0368
Chlamydia trachomatis pyruvate kinase 0.0032 0.0139 0.0509
Trypanosoma cruzi nucleobase transporter, putative 0.0043 0.02 0.0537
Trypanosoma cruzi tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0067 0.0341 0.093
Loa Loa (eye worm) agrin synaptic family protein 0.0046 0.0219 0.0607
Mycobacterium leprae Possible regulatory protein 0.0012 0.0021 0.0056
Loa Loa (eye worm) hypothetical protein 0.0248 0.1405 0.3899
Echinococcus multilocularis jumonji domain containing protein 0.0025 0.0098 0.0098
Echinococcus multilocularis rhodopsin orphan GPCR 0.0248 0.1405 0.1405
Schistosoma mansoni amine GPCR 0.0248 0.1405 0.1768
Echinococcus granulosus pyruvate kinase 0.0017 0.0046 0.0058
Echinococcus granulosus PHD finger protein rhinoceros 0.0018 0.0056 0.007
Trypanosoma cruzi glyceraldehyde 3-phosphate dehydrogenase, putative 0.0407 0.234 0.6486
Trypanosoma cruzi glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain, putative 0.0126 0.069 0.1898
Toxoplasma gondii nucleoside transporter protein 0.0043 0.02 0.0537
Trichomonas vaginalis Phosphoglycerol transferase I, putative 0.0017 0.0047 0.0139
Trichomonas vaginalis conserved hypothetical protein 0.0017 0.0047 0.0139
Trichomonas vaginalis conserved hypothetical protein 0.0019 0.0058 0.0176
Trypanosoma cruzi adenosine kinase, putative 0.0623 0.3604 1
Loa Loa (eye worm) cytochrome P450 family protein 0.0022 0.0076 0.0212
Brugia malayi SET domain containing protein 0.001 0.0008 0.0021
Brugia malayi Kazal-type serine protease inhibitor domain containing protein 0.0046 0.0219 0.0607
Echinococcus granulosus ecdysone induced protein 78C 0.0012 0.002 0.0026
Echinococcus granulosus pyruvate kinase 0.0032 0.0139 0.0175
Schistosoma mansoni neuropeptide F-like receptor 0.0248 0.1405 0.1768
Onchocerca volvulus 0.0248 0.1405 0.4372
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0045 0.0211 0.0568
Loa Loa (eye worm) hypothetical protein 0.0246 0.1394 0.3868
Echinococcus granulosus ribokinase 0.0071 0.0365 0.0459
Trypanosoma cruzi pyruvate kinase 2, putative 0.0032 0.0139 0.0368
Loa Loa (eye worm) hypothetical protein 0.0011 0.0011 0.003
Schistosoma mansoni neuropeptide receptor 0.0248 0.1405 0.1768
Trichomonas vaginalis set domain proteins, putative 0.0496 0.2864 1
Toxoplasma gondii Kazal-type serine protease inhibitor domain-containing protein 0.0046 0.0219 0.0589
Loa Loa (eye worm) hypothetical protein 0.0035 0.0155 0.0431
Plasmodium vivax dihydrolipoyl dehydrogenase, apicoplast, putative 0.0016 0.0042 0.009
Loa Loa (eye worm) hypothetical protein 0.0026 0.01 0.0277
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0063 0.0318 0.0399
Plasmodium vivax thioredoxin reductase, putative 0.0046 0.0218 0.085
Trichomonas vaginalis phosphofructokinase, putative 0.0058 0.0287 0.0976
Trypanosoma brucei nucleobase/nucleoside transporter 8.1, putative 0.0043 0.02 0.0537
Echinococcus granulosus single minded 2 0.0035 0.0154 0.0194
Brugia malayi Nuclear hormone receptor family member nhr-1 0.0012 0.002 0.0057
Loa Loa (eye worm) unidentified vitellogenin-linked transcript protein 6 0.0248 0.1405 0.3899
Mycobacterium tuberculosis Probable lipase LipE 0.0035 0.0155 0.1126
Echinococcus multilocularis cpg binding protein 0.0029 0.0122 0.0122
Brugia malayi steroid hormone receptor 0.0012 0.002 0.0057
Loa Loa (eye worm) G protein signaling regulator EGL-10 0.0019 0.0058 0.0161
Schistosoma mansoni rotamase 0.0032 0.0139 0.0175
Leishmania major adenosine kinase-like protein 0.0071 0.0365 0.0997
Onchocerca volvulus 0.0046 0.0219 0.0626
Echinococcus multilocularis serotonin receptor 0.0248 0.1405 0.1405
Loa Loa (eye worm) 6-phosphofructokinase 0.0213 0.12 0.3328
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0028 0.0114 0.0317
Echinococcus granulosus 7tm_1 domain containing protein 0.0248 0.1405 0.1768
Echinococcus granulosus netrin receptor unc 5 0.0028 0.0114 0.0144
Trichomonas vaginalis conserved hypothetical protein 0.0071 0.0365 0.1251
Chlamydia trachomatis fructose-6-phosphate phosphotransferase 0.0058 0.0287 0.1146
Trypanosoma brucei adenosine transporter 2, putative 0.0043 0.02 0.0537
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0013 0.0028 0.007
Onchocerca volvulus Putative organic anion transporter 0.0067 0.0344 0.1022
Plasmodium falciparum glutathione reductase 0.0016 0.0042 0.009
Schistosoma mansoni axis inhibition protein axin 0.0019 0.0058 0.0073
Entamoeba histolytica phosphofructokinase, putative 0.0213 0.12 0.5095
Onchocerca volvulus 0.0148 0.0816 0.2512
Echinococcus granulosus histone lysine methyltransferase setb 0.0063 0.0319 0.0402
Loa Loa (eye worm) hypothetical protein 0.0035 0.0155 0.0431
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0016 0.0042 0.0042
Trichomonas vaginalis conserved hypothetical protein 0.0017 0.0047 0.0139
Schistosoma mansoni blooms syndrome DNA helicase 0.0017 0.0047 0.0059
Onchocerca volvulus Putative pyridoxal kinase 0.0071 0.0365 0.1089
Trichomonas vaginalis conserved hypothetical protein 0.0017 0.0047 0.0139
Echinococcus multilocularis Transcription factor, JmjC domain containing protein 0.006 0.03 0.03
Mycobacterium ulcerans esterase/lipase LipP 0.0035 0.0155 0.0608
Mycobacterium ulcerans arylsulfatase AtsD 0.0017 0.0047 0.0143
Trichomonas vaginalis DNA helicase recq, putative 0.0011 0.0015 0.0025
Loa Loa (eye worm) hypothetical protein 0.0012 0.002 0.0056
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0016 0.0042 0.0099
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0063 0.0318 0.0318
Echinococcus granulosus thioredoxin glutathione reductase 0.0046 0.0218 0.0275
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0011 0.0011 0.0009
Loa Loa (eye worm) phosphofructokinase 0.0213 0.12 0.3328
Plasmodium vivax dihydrolipoyl dehydrogenase, mitochondrial, putative 0.0016 0.0042 0.009
Schistosoma mansoni biogenic amine receptor 0.0248 0.1405 0.1768
Echinococcus granulosus Regulator of G protein signaling 20 0.0019 0.0058 0.0073
Mycobacterium ulcerans hypothetical protein 0.002 0.0066 0.0222
Schistosoma mansoni tyrosyl-DNA phosphodiesterase 0.0067 0.0341 0.0429
Plasmodium falciparum dihydrolipoyl dehydrogenase, apicoplast 0.0016 0.0042 0.009
Loa Loa (eye worm) hypothetical protein 0.0067 0.0344 0.0955
Mycobacterium ulcerans lipase LipD 0.0035 0.0155 0.0608
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.0035 0.0155 0.1126
Echinococcus granulosus rhodopsin orphan GPCR 0.0248 0.1405 0.1768
Onchocerca volvulus 0.0026 0.0102 0.0259
Trypanosoma cruzi nucleoside transporter-like, putative 0.0043 0.02 0.0537
Echinococcus multilocularis ecdysone induced protein 78C 0.0012 0.002 0.002
Loa Loa (eye worm) hypothetical protein 0.0248 0.1405 0.3899
Trichomonas vaginalis soluble guanylate cyclase gcy, putative 0.0012 0.0021 0.0045
Loa Loa (eye worm) hypothetical protein 0.0248 0.1405 0.3899
Mycobacterium tuberculosis Probable hydrolase 0.0035 0.0155 0.1126
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.0012 0.002 0.0026
Loa Loa (eye worm) hypothetical protein 0.0248 0.1405 0.3899
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0248 0.1405 0.1405
Onchocerca volvulus 0.0067 0.0344 0.1022
Echinococcus multilocularis G-protein coupled receptor, putative 0.0248 0.1405 0.1405
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0183 0.1024 0.3559
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.0012 0.002 0.0026
Loa Loa (eye worm) hypothetical protein 0.0248 0.1405 0.3899
Trypanosoma cruzi glyceraldehyde 3-phosphate dehydrogenase, cytosolic, putative 0.0407 0.234 0.6486
Trichomonas vaginalis phosphofructokinase, putative 0.0058 0.0287 0.0976
Echinococcus granulosus rhodopsin orphan GPCR 0.0248 0.1405 0.1768
Echinococcus multilocularis lysine specific demethylase 5A 0.0022 0.0079 0.0079
Schistosoma mansoni organic anion transporter 0.0067 0.0344 0.0433
Entamoeba histolytica pyrophosphate-dependent phosphofructokinase 0.0058 0.0287 0.1169
Schistosoma mansoni netrin receptor unc5 0.0028 0.0114 0.0144
Schistosoma mansoni organic anion transporter 0.0067 0.0344 0.0433
Entamoeba histolytica glyceraldehyde-3-phosphate dehydrogenase, putative 0.0407 0.234 1
Leishmania major mitogen activated protein kinase, putative,map kinase, putative 0.0062 0.031 0.0843
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.0026 0.0102 0.0284
Loa Loa (eye worm) AGC/GRK/GRK protein kinase 0.0019 0.0061 0.017
Schistosoma mansoni neuropeptide receptor 0.0248 0.1405 0.1768
Schistosoma mansoni muscarinic acetylcholine (GAR) receptor 0.0248 0.1405 0.1768
Schistosoma mansoni regulator of G protein signaling 17 19 20 (rgs17 19 20) 0.0019 0.0058 0.0073
Brugia malayi hypothetical protein 0.0248 0.1405 0.3899
Onchocerca volvulus 0.0035 0.0154 0.0422
Schistosoma mansoni biogenic amine receptor 0.0248 0.1405 0.1768
Trypanosoma brucei adenosine transporter 2 0.0043 0.02 0.0537
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.0012 0.002 0.0026
Trichomonas vaginalis adenylate and guanylate cyclases, putative 0.0012 0.0021 0.0045
Trichomonas vaginalis conserved hypothetical protein 0.0017 0.0047 0.0139
Trypanosoma cruzi glyceraldehyde 3-phosphate dehydrogenase, putative 0.0126 0.069 0.1898
Echinococcus granulosus pseudouridine metabolizing bifunctional protein 0.0071 0.0365 0.0459
Entamoeba histolytica hypothetical protein 0.0019 0.0058 0.0185
Loa Loa (eye worm) hypothetical protein 0.0012 0.002 0.0056
Schistosoma mansoni ancient conserved domain protein 2 (cyclin m2) 0.0248 0.1405 0.1768
Leishmania major glyceraldehyde 3-phosphate dehydrogenase, glycosomal 0.0407 0.234 0.6486
Trypanosoma brucei glyceraldehyde 3-phosphate dehydrogenase, glycosomal 0.0407 0.234 0.6486
Schistosoma mansoni hypothetical protein 0.0075 0.0391 0.0492
Trypanosoma brucei cytochrome P450, putative 0.0022 0.0076 0.0194
Trichomonas vaginalis conserved hypothetical protein 0.0019 0.0058 0.0176
Mycobacterium tuberculosis Probable aldehyde dehydrogenase 0.0059 0.0295 0.2236
Loa Loa (eye worm) hypothetical protein 0.0248 0.1405 0.3899
Schistosoma mansoni transcription factor LCR-F1 0.0075 0.0391 0.0492
Loa Loa (eye worm) hypothetical protein 0.0248 0.1405 0.3899
Brugia malayi Nuclear hormone receptor family member nhr-14 0.0012 0.002 0.0057
Loa Loa (eye worm) sodium-independent organic anion transporter 0.0067 0.0344 0.0955
Leishmania major ATP-dependent phosphofructokinase 0.0213 0.12 0.3316
Schistosoma mansoni myosin xvIII 0.0248 0.1405 0.1768
Loa Loa (eye worm) glutathione reductase 0.0046 0.0218 0.0606
Loa Loa (eye worm) hypothetical protein 0.0248 0.1405 0.3899
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0063 0.0318 0.0399
Trichomonas vaginalis glyceraldehyde 3-phosphate dehydrogenase, putative 0.0407 0.234 0.8166
Trichomonas vaginalis D-aminoacylase, putative 0.0035 0.0155 0.0517
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0063 0.0318 0.0399
Trypanosoma brucei adenosine transporter 2 0.0043 0.02 0.0537
Entamoeba histolytica hypothetical protein 0.0075 0.0391 0.1617
Echinococcus granulosus ankyrin repeat and death domain containing protein 0.0028 0.0114 0.0144
Entamoeba histolytica peptidyl-prolyl cis-trans isomerase, putative 0.0032 0.0135 0.0515
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0248 0.1405 0.1768
Echinococcus granulosus allatostatin A receptor 0.0248 0.1405 0.1768
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0063 0.0319 0.0402
Trichomonas vaginalis chromobox protein, putative 0.0044 0.0205 0.0691
Loa Loa (eye worm) hypothetical protein 0.0248 0.1405 0.3899
Brugia malayi follicle stimulating hormone receptor 0.0475 0.2741 0.7604
Giardia lamblia PHD finger protein 15 0.0018 0.0056 0.006
Echinococcus multilocularis rhodopsin orphan GPCR 0.0248 0.1405 0.1405
Treponema pallidum glyceraldehyde 3-phosphate dehydrogenase (gap) 0.0407 0.234 1
Loa Loa (eye worm) hypothetical protein 0.0248 0.1405 0.3899
Echinococcus multilocularis regulator of G protein signaling 0.0019 0.0058 0.0058
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0248 0.1405 0.1768
Loa Loa (eye worm) hypothetical protein 0.0067 0.0344 0.0955
Echinococcus granulosus rhodopsin orphan GPCR 0.0248 0.1405 0.1768
Toxoplasma gondii phosphofructokinase PFKII 0.0058 0.0287 0.0778
Trichomonas vaginalis conserved hypothetical protein 0.0017 0.0047 0.0139
Loa Loa (eye worm) hypothetical protein 0.0016 0.0042 0.0115
Echinococcus multilocularis pyruvate kinase 0.0032 0.0139 0.0139
Echinococcus granulosus RUN 0.0012 0.0021 0.0027
Mycobacterium tuberculosis NAD(P)H quinone reductase LpdA 0.0116 0.0632 0.4923
Schistosoma mansoni lipoxygenase 0.0074 0.0383 0.0481
Mycobacterium ulcerans dihydrolipoamide dehydrogenase 0.0016 0.0042 0.012
Toxoplasma gondii 6-phosphofructokinase 0.0058 0.0287 0.0778
Trypanosoma brucei adenosine transporter 2, putative 0.0043 0.02 0.0537
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0183 0.1024 0.3559
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.0183 0.1024 0.4341
Schistosoma mansoni glyceraldehyde-3-phosphate dehydrogenase (phosphorylating) 0.0407 0.234 0.2944
Mycobacterium ulcerans aldehyde dehydrogenase 0.0059 0.0295 0.1207
Mycobacterium tuberculosis Conserved hypothetical protein 0.002 0.0066 0.0411
Onchocerca volvulus Heterochromatin protein 1 homolog 0.0024 0.0092 0.0227
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0045 0.0211 0.0568
Echinococcus granulosus aryl hydrocarbon receptor 0.0012 0.0021 0.0026
Schistosoma mansoni amine GPCR 0.0248 0.1405 0.1768
Leishmania major tagatose-6-phosphate kinase-like protein 0.0071 0.0365 0.0997
Wolbachia endosymbiont of Brugia malayi dihydrolipoamide dehydrogenase E3 component 0.0016 0.0042 0.0152
Mycobacterium tuberculosis Possible arylsulfatase AtsA (aryl-sulfate sulphohydrolase) (arylsulphatase) 0.0017 0.0047 0.0265
Echinococcus granulosus regulator of G protein signaling 3 0.0019 0.0058 0.0073
Echinococcus granulosus adenosine kinase 0.0623 0.3604 0.4534
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0063 0.0318 0.0881
Mycobacterium ulcerans sugar phosphate isomerases/epimerases 0.002 0.0066 0.0222
Schistosoma mansoni single-minded 0.0047 0.0226 0.0284
Toxoplasma gondii nucleoside transporter protein 0.0043 0.02 0.0537
Echinococcus granulosus regulator of G protein signaling 7 0.0019 0.0058 0.0073
Entamoeba histolytica hypothetical protein 0.0075 0.0391 0.1617
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0009 0.0003 0.0003
Schistosoma mansoni hypothetical protein 0.0332 0.1899 0.2389
Loa Loa (eye worm) glyceraldehyde-3-phosphate dehydrogenase 0.0281 0.1599 0.4437
Brugia malayi GnHR receptor homolog 0.0248 0.1405 0.3899
Mycobacterium leprae Probable pyruvate kinase PykA 0.0032 0.0139 0.1052
Brugia malayi Cytochrome P450 family protein 0.0048 0.0232 0.0643
Onchocerca volvulus 0.0026 0.0102 0.0259
Brugia malayi Kazal-type serine protease inhibitor domain containing protein 0.0046 0.0219 0.0607
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0248 0.1405 0.1405
Trypanosoma brucei glyceraldehyde 3-phosphate dehydrogenase, glycosomal 0.0407 0.234 0.6486
Onchocerca volvulus Netrin receptor homolog 0.0028 0.0114 0.0296
Brugia malayi hypoxia-induced factor 1 0.0146 0.0807 0.224
Echinococcus granulosus lipoxygenase domain containing protein 0.0012 0.0021 0.0027
Trypanosoma brucei nucleoside transporter 1, putative 0.0043 0.02 0.0537
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0016 0.0042 0.0099
Trichomonas vaginalis glyceraldehyde 3-phosphate dehydrogenase, putative 0.014 0.0773 0.268
Echinococcus granulosus lamin dm0 0.0026 0.0102 0.0129
Loa Loa (eye worm) hypothetical protein 0.0067 0.0344 0.0955
Mycobacterium ulcerans endonuclease IV 0.0076 0.0394 0.1632
Schistosoma mansoni regulator of G protein signaling 0.0019 0.0058 0.0073
Loa Loa (eye worm) hypothetical protein 0.0246 0.1394 0.3868
Trypanosoma brucei glyceraldehyde-3-phosphate dehydrogenase, putative 0.0267 0.1514 0.419
Loa Loa (eye worm) neuropeptide F receptor 0.0248 0.1405 0.3899
Schistosoma mansoni serine/threonine protein kinase 0.0019 0.0061 0.0077
Entamoeba histolytica fructokinase, putative 0.0071 0.0365 0.1507
Leishmania major nucleobase transporter 0.0043 0.02 0.0537
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0063 0.0319 0.0402
Trichomonas vaginalis guanylate cyclase, putative 0.0012 0.0021 0.0045
Mycobacterium tuberculosis Probable glyceraldehyde 3-phosphate dehydrogenase Gap (GAPDH) 0.0141 0.0775 0.6056
Loa Loa (eye worm) follicle stimulating hormone receptor 0.0475 0.2741 0.7604
Trichomonas vaginalis 6-phosphofructokinase, putative 0.0058 0.0287 0.0976
Brugia malayi Heterochromatin protein 1 0.0044 0.0205 0.0569
Brugia malayi Nuclear hormone receptor family member nhr-40 0.0012 0.002 0.0057
Brugia malayi Doublecortin family protein 0.0012 0.0021 0.0059
Trichomonas vaginalis pyruvate kinase, putative 0.0032 0.0139 0.0459
Loa Loa (eye worm) neuropeptide F receptor 0.0248 0.1405 0.3899
Echinococcus multilocularis rhodopsin orphan GPCR 0.0248 0.1405 0.1405
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0012 0.002 0.0057
Schistosoma mansoni 6-phosphofructokinase 0.0213 0.12 0.1509
Echinococcus multilocularis axis inhibition protein axin 0.0019 0.0058 0.0058
Echinococcus granulosus neuropeptides capa receptor 0.0248 0.1405 0.1768
Loa Loa (eye worm) hypothetical protein 0.0019 0.0058 0.0161
Brugia malayi regulator of G-protein signaling egl-10 0.0019 0.0058 0.0161
Trypanosoma brucei nucleoside transporter 1, putative 0.0043 0.02 0.0537
Echinococcus granulosus geminin 0.0332 0.1899 0.2389
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0013 0.0028 0.007
Echinococcus multilocularis thyrotropin releasing hormone receptor 0.0248 0.1405 0.1405
Echinococcus multilocularis regulator of G protein signaling 7 0.0019 0.0058 0.0058
Leishmania major lanosterol 14-alpha-demethylase, putative 0.0011 0.0014 0.0021
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0016 0.0042 0.0115
Echinococcus granulosus fmrfamide receptor 0.0248 0.1405 0.1768
Echinococcus granulosus mitogen activated protein kinase 3 0.0062 0.031 0.039
Entamoeba histolytica nucleoside transporter, putative 0.0246 0.1394 0.5932
Trichomonas vaginalis conserved hypothetical protein 0.0032 0.0139 0.046
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0248 0.1405 0.1768
Echinococcus granulosus glyceraldehyde 3 phosphate dehydrogenase 0.0407 0.234 0.2944
Brugia malayi hypothetical protein 0.0248 0.1405 0.3899
Brugia malayi hypothetical protein 0.0248 0.1405 0.3899
Echinococcus multilocularis neuropeptide receptor 0.0248 0.1405 0.1405
Echinococcus granulosus thyrotropin releasing hormone receptor 0.0248 0.1405 0.1768
Trichomonas vaginalis conserved hypothetical protein 0.0011 0.0011 0.0009
Loa Loa (eye worm) hypothetical protein 0.0248 0.1405 0.3899
Plasmodium vivax 6-phosphofructokinase, putative 0.0058 0.0287 0.1145
Mycobacterium leprae PROBABLE ENDONUCLEASE IV END (ENDODEOXYRIBONUCLEASE IV) (APURINASE) 0.0076 0.0394 0.3202
Brugia malayi Tachykinin-like peptides receptor 99D 0.0248 0.1405 0.3899
Entamoeba histolytica glyceraldehyde-3-phosphate dehydrogenase, putative 0.0407 0.234 1
Echinococcus multilocularis tachykinin peptides receptor 99D 0.0248 0.1405 0.1405
Trichomonas vaginalis conserved hypothetical protein 0.0024 0.0092 0.0296
Loa Loa (eye worm) doublecortin family protein 0.0012 0.0021 0.0059
Echinococcus multilocularis chromobox protein 1 0.0044 0.0205 0.0205
Echinococcus multilocularis geminin 0.0332 0.1899 0.1899
Onchocerca volvulus Dopamine\/Ecdysteroid receptor homolog 0.0248 0.1405 0.4372
Brugia malayi hypothetical protein 0.0067 0.0344 0.0955
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0183 0.1024 0.3559
Leishmania major hypothetical protein, conserved 0.0035 0.0155 0.0414
Onchocerca volvulus 0.0071 0.0365 0.1089
Brugia malayi Nuclear hormone receptor family member nhr-3 0.0012 0.002 0.0057
Loa Loa (eye worm) thioredoxin reductase 0.0046 0.0218 0.0606
Echinococcus multilocularis serotonin receptor 0.0248 0.1405 0.1405
Schistosoma mansoni dihydrolipoamide dehydrogenase 0.0016 0.0042 0.0053
Entamoeba histolytica Hypothetical protein T24C12.3, putative 0.0071 0.0365 0.1507
Onchocerca volvulus Pyruvate kinase homolog 0.0032 0.0139 0.0374
Echinococcus granulosus nuclear factor of activated T cells 5 0.0144 0.0796 0.1002
Brugia malayi Pyruvate kinase, alpha/beta domain containing protein 0.001 0.0006 0.0017
Echinococcus multilocularis glyceraldehyde 3 phosphate dehydrogenase 0.0407 0.234 0.234
Onchocerca volvulus 0.0248 0.1405 0.4372
Mycobacterium tuberculosis Probable lipase LipD 0.0035 0.0155 0.1126
Treponema pallidum diphosphate--fructose-6-phosphate 1-phosphotransferase 0.0213 0.12 0.5037
Loa Loa (eye worm) hypothetical protein 0.0248 0.1405 0.3899
Schistosoma mansoni glyceraldehyde-3-phosphate dehydrogenase (phosphorylating) 0.0407 0.234 0.2944
Echinococcus multilocularis transfer RNA-Lys 0.0035 0.0154 0.0154
Trypanosoma cruzi glyceraldehyde-3-phosphate dehydrogenase, putative 0.0267 0.1514 0.419
Mycobacterium tuberculosis Possible hydrolase 0.0017 0.0047 0.0265
Leishmania major protein kinase, putative 0.0013 0.0024 0.0049
Onchocerca volvulus Putative organic anion transporter 0.0067 0.0344 0.1022
Onchocerca volvulus 0.0067 0.0344 0.1022
Loa Loa (eye worm) glyceraldehyde 3-phosphate dehydrogenase 0.0267 0.1515 0.4204
Brugia malayi sulfakinin receptor protein 0.0248 0.1405 0.3899
Loa Loa (eye worm) hypothetical protein 0.0019 0.0058 0.0161
Trypanosoma brucei pyruvate kinase 1 0.0032 0.0139 0.0368
Trichomonas vaginalis glyceraldehyde 3-phosphate dehydrogenase, putative 0.0407 0.234 0.8166
Onchocerca volvulus 0.0248 0.1405 0.4372
Trichomonas vaginalis conserved hypothetical protein 0.0012 0.0021 0.0045
Plasmodium vivax SET domain protein, putative 0.0063 0.0319 0.1285
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0016 0.0042 0.0099
Giardia lamblia Ribokinase 0.0071 0.0365 0.1406
Brugia malayi sodium-independent organic anion transporter family protein 0.0067 0.0344 0.0955
Brugia malayi larval opioid receptor 0.0248 0.1405 0.3899
Schistosoma mansoni cpg binding protein 0.0028 0.0112 0.0141
Loa Loa (eye worm) CXXC zinc finger family protein 0.0028 0.0112 0.0312
Schistosoma mansoni peptide (FMRFamide/neurokinin-3)-like receptor 0.0248 0.1405 0.1768
Echinococcus multilocularis regulator of G protein signaling 7 0.0019 0.0058 0.0058
Schistosoma mansoni ubiquitin-specific peptidase 2 (C19 family) 0.0045 0.0211 0.0265
Toxoplasma gondii protease inhibitor PI2 0.0046 0.0219 0.0589
Plasmodium vivax 6-phosphofructokinase, putative 0.0058 0.0287 0.1145
Trichomonas vaginalis phosphofructokinase, putative 0.0058 0.0287 0.0976
Echinococcus multilocularis GPCR, family 2 0.0016 0.0042 0.0042
Trypanosoma cruzi nucleoside transporter 1, putative 0.0043 0.02 0.0537
Schistosoma mansoni chromobox protein 0.0044 0.0205 0.0258
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0012 0.002 0.0026
Brugia malayi Pyruvate kinase, muscle isozyme 0.0032 0.0139 0.0385
Trichomonas vaginalis conserved hypothetical protein 0.0017 0.0047 0.0139
Schistosoma mansoni histamine-responsive GPCR (AAF21638) 0.0248 0.1405 0.1768
Leishmania major ATP-dependent DEAD/H DNA helicase recQ, putative 0.0011 0.0015 0.0023
Loa Loa (eye worm) latrophilin receptor protein 2 0.0016 0.0042 0.0115
Loa Loa (eye worm) cytochrome P450 family protein 0.0048 0.0232 0.0643
Echinococcus multilocularis rhodopsin orphan GPCR 0.0248 0.1405 0.1405
Onchocerca volvulus 0.0248 0.1405 0.4372
Loa Loa (eye worm) intermediate filament protein 0.0026 0.0102 0.0284
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0045 0.0211 0.0711
Echinococcus granulosus g protein coupled receptor 0.0248 0.1405 0.1768
Mycobacterium tuberculosis Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB 0.0105 0.0564 0.4377
Brugia malayi hypothetical protein 0.0248 0.1405 0.3899
Toxoplasma gondii Kazal-type serine protease inhibitor domain-containing protein 0.0046 0.0219 0.0589
Toxoplasma gondii glyceraldehyde-3-phosphate dehydrogenase GAPDH1 0.0407 0.234 0.6486
Brugia malayi hypothetical protein 0.0248 0.1405 0.3899
Brugia malayi hypothetical protein 0.0239 0.135 0.3744
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.0035 0.0155 0.0608
Loa Loa (eye worm) hypothetical protein 0.0248 0.1405 0.3899
Brugia malayi hypothetical protein 0.0248 0.1405 0.3899
Echinococcus granulosus neuropeptide Y receptor 0.0248 0.1405 0.1768
Echinococcus multilocularis dro:myosuppressin receptor 0.0248 0.1405 0.1405
Loa Loa (eye worm) glyceraldehyde-3-phosphate dehydrogenase 0.0281 0.1599 0.4437
Brugia malayi prostaglandin transporter 0.0067 0.0344 0.0955
Trichomonas vaginalis conserved hypothetical protein 0.0017 0.0047 0.0139
Giardia lamblia Glyceraldehyde 3-phosphate dehydrogenase 0.0407 0.234 1
Brugia malayi bHLH-PAS transcription factor 0.0035 0.0154 0.0427
Mycobacterium leprae conserved hypothetical protein 0.0035 0.0155 0.1192
Loa Loa (eye worm) PHD-finger family protein 0.0018 0.0056 0.0155
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0061 0.031 0.0389
Mycobacterium tuberculosis Ribokinase RbsK 0.0071 0.0365 0.2796
Brugia malayi F/Y-rich N-terminus family protein 0.0017 0.0047 0.0131
Echinococcus granulosus neuropeptide Y receptor 0.0248 0.1405 0.1768
Loa Loa (eye worm) hypothetical protein 0.0248 0.1405 0.3899
Schistosoma mansoni ribokinase 0.0071 0.0365 0.0459
Brugia malayi PAS domain containing protein 0.0047 0.0226 0.0627
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.0012 0.002 0.0026
Loa Loa (eye worm) hypothetical protein 0.0032 0.0139 0.0385
Trichomonas vaginalis conserved hypothetical protein 0.0017 0.0047 0.0139
Echinococcus granulosus peptide allatostatin:somatostatin 0.0248 0.1405 0.1768
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.0012 0.002 0.0057
Brugia malayi hypothetical protein 0.0012 0.0021 0.0059
Echinococcus multilocularis lamin dm0 0.0026 0.0102 0.0102
Mycobacterium ulcerans fructokinase, PfkB 0.0071 0.0365 0.151
Brugia malayi beta-lactamase family protein 0.0035 0.0155 0.0431
Echinococcus granulosus equilibrative nucleoside transporter 3 0.0246 0.1394 0.1754
Schistosoma mansoni neuropeptide f receptor 76f 0.0248 0.1405 0.1768
Trichomonas vaginalis glyceraldehyde 3-phosphate dehydrogenase, putative 0.0407 0.234 0.8166
Trypanosoma cruzi peptidyl-prolyl cis-trans isomerase 0.0032 0.0135 0.0356
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0045 0.0211 0.0585
Trichomonas vaginalis equilibrative nucleoside transporter, putative 0.0043 0.02 0.0672
Schistosoma mansoni ankyrin 23/unc44 0.0028 0.0114 0.0144
Trichomonas vaginalis conserved hypothetical protein 0.0017 0.0047 0.0139
Schistosoma mansoni neuropeptide F-like receptor 0.0248 0.1405 0.1768
Echinococcus multilocularis peptide (allatostatin:somatostatin) 0.0248 0.1405 0.1405
Brugia malayi hypothetical protein 0.0075 0.0391 0.1085
Schistosoma mansoni histamine h1 receptor 0.0248 0.1405 0.1768
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0016 0.0042 0.0099
Echinococcus multilocularis g protein coupled receptor 0.0248 0.1405 0.1405
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0016 0.0042 0.0099
Brugia malayi hypothetical protein 0.0012 0.0021 0.0059
Brugia malayi glutathione reductase 0.0046 0.0218 0.0606
Entamoeba histolytica kinase, PfkB family 0.0071 0.0365 0.1507
Echinococcus multilocularis Aryl hydrocarbon receptor nuclear 0.0012 0.0021 0.0021
Mycobacterium ulcerans beta-lactamase 0.0035 0.0155 0.0608
Brugia malayi hypothetical protein 0.0067 0.0344 0.0955
Schistosoma mansoni lipoxygenase 0.0052 0.0252 0.0317
Trichomonas vaginalis glutathione reductase, putative 0.0016 0.0042 0.012
Echinococcus multilocularis rhodopsin orphan GPCR 0.0248 0.1405 0.1405
Trichomonas vaginalis conserved hypothetical protein 0.0012 0.0021 0.0045
Echinococcus multilocularis tyrosyl DNA phosphodiesterase 1 0.0067 0.0341 0.0341
Schistosoma mansoni hypothetical protein 0.0011 0.0014 0.0018
Trypanosoma cruzi STE/STE11 serine/threonine-protein kinase, putative 0.0013 0.0024 0.0049
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.0012 0.002 0.002
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0062 0.031 0.0843
Entamoeba histolytica ribokinase, putative 0.0071 0.0365 0.1507
Loa Loa (eye worm) hypothetical protein 0.0248 0.1405 0.3899
Loa Loa (eye worm) hypothetical protein 0.0017 0.0047 0.0132
Trypanosoma brucei adenosine kinase, putative 0.0623 0.3604 1
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0436 0.251 0.6965
Loa Loa (eye worm) PXA domain-containing protein 0.0019 0.0058 0.0161
Echinococcus granulosus Peptidase C19 ubiquitin carboxyl terminal hydrolase 2 0.0045 0.0211 0.0265
Trichomonas vaginalis conserved hypothetical protein 0.0017 0.0047 0.0139
Schistosoma mansoni retinoblastoma-binding protein 4 (rbbp4) 0.0028 0.0116 0.0145
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0016 0.0042 0.0052
Loa Loa (eye worm) hypothetical protein 0.0045 0.0211 0.0585
Loa Loa (eye worm) hypothetical protein 0.0046 0.0219 0.0607
Loa Loa (eye worm) hypothetical protein 0.0012 0.0021 0.0059
Brugia malayi latrophilin 2 splice variant baaae 0.0034 0.0149 0.0415
Trichomonas vaginalis conserved hypothetical protein 0.0017 0.0047 0.0139
Treponema pallidum diphosphate--fructose-6-phosphate 1-phosphotransferase 0.0058 0.0287 0.1064
Loa Loa (eye worm) hypothetical protein 0.0017 0.0047 0.0132
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0063 0.0318 0.0399
Schistosoma mansoni hypothetical protein 0.0016 0.0042 0.0052
Entamoeba histolytica glyceraldehyde-3-phosphate dehydrogenase, putative 0.0407 0.234 1
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0016 0.0042 0.0099
Plasmodium falciparum ATP-dependent 6-phosphofructokinase 0.0058 0.0287 0.1145
Schistosoma mansoni amine GPCR 0.0248 0.1405 0.1768
Entamoeba histolytica hypothetical protein 0.0075 0.0391 0.1617
Giardia lamblia Fructose-bisphosphate aldolase 0.0183 0.1024 0.4274
Toxoplasma gondii endonuclease IV APN 0.0076 0.0394 0.1076
Schistosoma mansoni serine/threonine protein kinase 0.0019 0.0061 0.0077
Brugia malayi jmjC domain containing protein 0.0024 0.0088 0.0244
Schistosoma mansoni hypothetical protein 0.0248 0.1405 0.1768
Brugia malayi G protein-coupled receptor 0.0248 0.1405 0.3899
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0011 0.0013 0.0016
Brugia malayi CXXC zinc finger family protein 0.0028 0.0112 0.0312
Leishmania major PAS-domain containing phosphoglycerate kinase, putative 0.0012 0.0021 0.0039
Schistosoma mansoni jumonji/arid domain-containing protein 0.0024 0.0088 0.0111
Onchocerca volvulus Pyruvate kinase homolog 0.0032 0.0139 0.0374
Trypanosoma brucei hypothetical protein, conserved 0.0035 0.0155 0.0414
Loa Loa (eye worm) hypothetical protein 0.0035 0.0155 0.0431
Echinococcus multilocularis growth hormone secretagogue receptor type 1 0.0248 0.1405 0.1405
Echinococcus multilocularis biogenic amine (5HT) receptor 0.0248 0.1405 0.1405
Loa Loa (eye worm) pyruvate kinase 0.0032 0.0139 0.0385
Trypanosoma brucei adenosine transporter, putative 0.0043 0.02 0.0537
Treponema pallidum fructose-bisphosphate aldolase 0.0183 0.1024 0.4274
Mycobacterium ulcerans aldehyde dehydrogenase 0.0059 0.0295 0.1207
Leishmania major ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative 0.0045 0.0211 0.0568
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0183 0.1024 0.3559
Echinococcus granulosus rhodopsin orphan GPCR 0.0248 0.1405 0.1768
Leishmania major adenosine kinase, putative 0.0623 0.3604 1
Loa Loa (eye worm) hypothetical protein 0.0248 0.1405 0.3899
Echinococcus granulosus sex peptide receptor 0.0248 0.1405 0.1768
Echinococcus multilocularis 7TM GPCR, rhodopsin 0.0248 0.1405 0.1405
Echinococcus granulosus neuropeptides capa receptor 0.0248 0.1405 0.1768
Trichomonas vaginalis conserved hypothetical protein 0.0017 0.0047 0.0139
Echinococcus granulosus axis inhibition protein axin 0.0019 0.0058 0.0073
Trichomonas vaginalis conserved hypothetical protein 0.0017 0.005 0.0149
Giardia lamblia Hypothetical protein 0.0246 0.1394 0.5883
Brugia malayi Nuclear hormone receptor family member nhr-31 0.0012 0.002 0.0057
Trypanosoma brucei Lanosterol 14-alpha demethylase 0.0011 0.0014 0.0021
Loa Loa (eye worm) hypothetical protein 0.0012 0.002 0.0057
Onchocerca volvulus Putative organic anion transporter 0.0067 0.0344 0.1022
Schistosoma mansoni growth hormone secretagogue receptor 0.0248 0.1405 0.1768
Echinococcus multilocularis glyceraldehyde 3 phosphate dehydrogenase 0.0267 0.1515 0.1515
Echinococcus multilocularis Ankyrin 0.0028 0.0116 0.0116
Brugia malayi Thioredoxin reductase 0.0046 0.0218 0.0606
Trypanosoma cruzi mitogen activated protein kinase 4, putative 0.0062 0.031 0.0843
Schistosoma mansoni hypothetical protein 0.0016 0.0042 0.0052
Brugia malayi hypothetical protein 0.0071 0.0365 0.1013
Giardia lamblia Pyruvate kinase 0.0017 0.0046 0.0018
Leishmania major aldehyde dehydrogenase, mitochondrial precursor 0.0059 0.0295 0.0801
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.0012 0.002 0.002
Leishmania major trypanothione reductase 0.0046 0.0218 0.0588
Echinococcus granulosus regulator of G protein signaling 7 0.0019 0.0058 0.0073
Loa Loa (eye worm) hypothetical protein 0.0046 0.0219 0.0607
Schistosoma mansoni lamin 0.0026 0.0102 0.0129
Giardia lamblia Kinase, CMGC MAPK 0.0062 0.031 0.1166
Mycobacterium tuberculosis Probable esterase LipL 0.0035 0.0155 0.1126
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0248 0.1405 0.1405
Trypanosoma brucei nucleobase/nucleoside transporter 8.1, putative 0.0043 0.02 0.0537
Brugia malayi hypothetical protein 0.0248 0.1405 0.3899
Plasmodium vivax glutathione reductase, putative 0.0046 0.0218 0.085
Echinococcus granulosus cytoplasmic intermediate filament protein 0.0013 0.0023 0.0029
Echinococcus granulosus arachidonate 5 lipoxygenase 0.0074 0.0383 0.0481
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0248 0.1405 0.1768
Trichomonas vaginalis equilibrative nucleoside transporter, putative 0.0043 0.02 0.0672
Echinococcus multilocularis allatostatin A receptor 0.0248 0.1405 0.1405
Trichomonas vaginalis phosphofructokinase, putative 0.0213 0.12 0.4173
Toxoplasma gondii pyruvate kinase PyKII 0.0017 0.0046 0.011
Loa Loa (eye worm) hypothetical protein 0.0012 0.002 0.0057
Loa Loa (eye worm) hypothetical protein 0.0019 0.0061 0.017
Brugia malayi beta-lactamase family protein 0.0035 0.0155 0.0431
Leishmania major nucleoside transporter 1, putative 0.0043 0.02 0.0537
Echinococcus multilocularis orexin receptor type 2 0.0248 0.1405 0.1405
Trichomonas vaginalis phosphofructokinase, putative 0.0058 0.0287 0.0976
Echinococcus multilocularis rhodopsin orphan GPCR 0.0248 0.1405 0.1405
Loa Loa (eye worm) hypothetical protein 0.0046 0.0219 0.0607
Plasmodium falciparum dihydrolipoyl dehydrogenase, mitochondrial 0.0016 0.0042 0.009
Entamoeba histolytica nucleoside transporter, putative 0.0043 0.02 0.0795
Toxoplasma gondii phosphofructokinase domain-containing protein 0.0058 0.0287 0.0778
Loa Loa (eye worm) hypothetical protein 0.0248 0.1405 0.3899
Echinococcus multilocularis follistatin 0.0046 0.0219 0.0219
Brugia malayi ecdysteroid receptor 0.0012 0.002 0.0057
Echinococcus granulosus glyceraldehyde 3 phosphate dehydrogenase 0.0407 0.234 0.2944
Brugia malayi Dopamine receptor protein 1 0.0248 0.1405 0.3899
Toxoplasma gondii nucleoside transporter protein 0.0043 0.02 0.0537
Echinococcus multilocularis g protein coupled receptor 0.0248 0.1405 0.1405
Loa Loa (eye worm) hypothetical protein 0.0248 0.1405 0.3899
Onchocerca volvulus 0.0248 0.1405 0.4372
Brugia malayi Cytochrome P450 family protein 0.0011 0.0014 0.0039
Echinococcus granulosus somatostatin receptor 0.0248 0.1405 0.1768
Echinococcus multilocularis peregrin 0.0018 0.0056 0.0056
Schistosoma mansoni hypothetical protein 0.0012 0.0021 0.0027
Onchocerca volvulus 0.007 0.0361 0.1076
Schistosoma mansoni rab6-interacting 0.0012 0.0021 0.0027
Loa Loa (eye worm) G-protein-linked acetylcholine receptor protein 2 0.0248 0.1405 0.3899
Entamoeba histolytica tagatose-6-phosphate kinase, putative 0.0071 0.0365 0.1507
Loa Loa (eye worm) hypothetical protein 0.0248 0.1405 0.3899
Echinococcus multilocularis 6 phosphofructokinase 0.0213 0.12 0.12
Schistosoma mansoni cellular tumor antigen P53 0.0148 0.0816 0.1027
Brugia malayi glyceraldehyde 3-phosphate dehydrogenase 0.0126 0.069 0.1913
Schistosoma mansoni z-protein (S1r protein) 0.0019 0.0058 0.0073
Entamoeba histolytica pyruvate kinase, putative 0.0023 0.0081 0.0286
Loa Loa (eye worm) heterochromatin protein 1 0.0044 0.0205 0.0569
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 8 0.0045 0.0211 0.0211
Trypanosoma brucei adenosine transporter 2, putative 0.0043 0.02 0.0537
Mycobacterium tuberculosis Probable 6-phosphofructokinase PfkA (phosphohexokinase) (phosphofructokinase) 0.0213 0.12 0.9441
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0248 0.1405 0.1768
Schistosoma mansoni pyruvate kinase 0.0032 0.0139 0.0175
Brugia malayi G protein-coupled receptor F59B2.13 0.0248 0.1405 0.3899
Schistosoma mansoni thyroid hormone receptor 0.0012 0.002 0.0026
Loa Loa (eye worm) hypothetical protein 0.0026 0.0102 0.0284
Schistosoma mansoni Tr4/Tr2 (homologue) 0.0012 0.002 0.0026
Brugia malayi Glyceraldehyde 3-phosphate dehydrogenase 0.0407 0.234 0.6492
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0013 0.0028 0.007
Brugia malayi cytochrome P450 0.0011 0.0014 0.0039
Onchocerca volvulus 0.0067 0.0344 0.1022
Mycobacterium tuberculosis Probable membrane NADH dehydrogenase NdhA 0.0105 0.0564 0.4377
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0248 0.1405 0.1768
Trichomonas vaginalis conserved hypothetical protein 0.0017 0.0047 0.0139
Echinococcus granulosus neuropeptide s receptor 0.0695 0.4029 0.5068
Trichomonas vaginalis equilibrative nucleoside transporter, putative 0.0043 0.02 0.0672
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0009 0.0003 0.0004
Echinococcus multilocularis equilibrative nucleoside transporter protein 0.0246 0.1394 0.1394
Trypanosoma brucei ribokinase, putative 0.0071 0.0365 0.0997
Brugia malayi hypothetical protein 0.0248 0.1405 0.3899
Schistosoma mansoni pyruvate kinase 0.0032 0.0139 0.0175
Echinococcus granulosus neuropeptide receptor 0.0248 0.1405 0.1768
Schistosoma mansoni protein kinase 0.0043 0.0203 0.0255
Plasmodium vivax pyruvate kinase, putative 0.0032 0.0139 0.0507
Schistosoma mansoni opsin-like receptor 0.0248 0.1405 0.1768
Trichomonas vaginalis CMGC family protein kinase 0.0062 0.031 0.1058
Mycobacterium ulcerans aldehyde dehydrogenase 0.0059 0.0295 0.1207
Trichomonas vaginalis conserved hypothetical protein 0.0017 0.0047 0.0139
Echinococcus multilocularis adenosine kinase 0.0623 0.3604 0.3604
Echinococcus granulosus tm gpcr rhodopsin 0.0248 0.1405 0.1768
Brugia malayi Steroid receptor seven-up type 2 0.0012 0.002 0.0057
Echinococcus multilocularis expressed protein 0.0046 0.0219 0.0219
Schistosoma mansoni lamin 0.0026 0.0102 0.0129
Loa Loa (eye worm) hypothetical protein 0.0248 0.1405 0.3899
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0063 0.0318 0.0881
Schistosoma mansoni opsin-like receptor 0.0248 0.1405 0.1768
Echinococcus multilocularis pyroglutamylated rfamide peptide receptor 0.0248 0.1405 0.1405
Trichomonas vaginalis conserved hypothetical protein 0.0017 0.0047 0.0139
Trichomonas vaginalis D-aminoacylase, putative 0.0035 0.0155 0.0517
Plasmodium vivax pyruvate kinase 2, putative 0.0017 0.0046 0.0108
Trypanosoma brucei purine nucleoside transporter 0.0043 0.02 0.0537
Brugia malayi Pre-SET motif family protein 0.0063 0.0319 0.0886
Echinococcus granulosus G protein coupled receptor 139 0.0248 0.1405 0.1768
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0248 0.1405 0.1768
Trypanosoma cruzi hypothetical protein, conserved 0.0035 0.0155 0.0414
Brugia malayi Melatonin receptor type 1A 0.0248 0.1405 0.3899
Echinococcus granulosus organic anion transporting polypeptide 30B 0.0067 0.0344 0.0433
Loa Loa (eye worm) beta-lactamase 0.0035 0.0155 0.0431
Loa Loa (eye worm) hypothetical protein 0.0248 0.1405 0.3899
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0013 0.0028 0.007
Schistosoma mansoni aldehyde dehydrogenase 0.0059 0.0295 0.0371
Echinococcus multilocularis nuclear factor of activated T cells 5 0.0144 0.0796 0.0796
Echinococcus multilocularis musashi 0.0026 0.0102 0.0102
Brugia malayi hypothetical protein 0.0248 0.1405 0.3899
Echinococcus multilocularis beta adrenergic receptor kinase 0.0019 0.0061 0.0061
Brugia malayi gonadotropin-releasing hormone receptor 2 0.0248 0.1405 0.3899
Echinococcus multilocularis alpha 1A adrenergic receptor 0.0248 0.1405 0.1405
Echinococcus granulosus lysine specific demethylase 5A 0.0024 0.0088 0.0111
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0016 0.0042 0.0052
Toxoplasma gondii aldehyde dehydrogenase 0.0059 0.0295 0.0801
Trypanosoma brucei ribokinase, putative 0.0071 0.0365 0.0997
Echinococcus granulosus GPCR family 2 0.0016 0.0042 0.0052
Loa Loa (eye worm) hypothetical protein 0.0248 0.1405 0.3899
Mycobacterium tuberculosis Probable sulfatase 0.0017 0.0047 0.0265
Mycobacterium ulcerans glyceraldehyde 3-phosphate dehydrogenase Gap 0.0407 0.234 1
Echinococcus granulosus A kinase anchor protein 10 mitochondrial 0.0019 0.0058 0.0073
Brugia malayi hypothetical protein 0.0158 0.0879 0.244
Trichomonas vaginalis conserved hypothetical protein 0.0017 0.0047 0.0139
Loa Loa (eye worm) hypothetical protein 0.0248 0.1405 0.3899
Loa Loa (eye worm) CYP4Cod1 0.0022 0.0076 0.0212
Brugia malayi 6-phosphofructokinase 0.0213 0.12 0.3328
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0013 0.0028 0.007
Onchocerca volvulus 0.0248 0.1405 0.4372
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.0014 0.0031 0.0069
Loa Loa (eye worm) hypothetical protein 0.0248 0.1405 0.3899
Trypanosoma cruzi pyruvate kinase 2, putative 0.0032 0.0139 0.0368
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.0012 0.002 0.0057
Trypanosoma brucei nucleobase/nucleoside transporter 8.1 0.0043 0.02 0.0537
Schistosoma mansoni hypothetical protein 0.0332 0.1899 0.2389

Activities

Activity type Activity value Assay description Source Reference
Potency (functional) = 4.4668 um PUBCHEM_BIOASSAY: VP16 counterscreen qHTS for inhibitors of ROR gamma transcriptional activity. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) = 22.3872 um PUBCHEM_BIOASSAY: qHTS Assay for Enhancers of SMN2 Splice Variant Expression. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) 39.8107 uM PUBCHEM_BIOASSAY: Inhibitors of the vitamin D receptor (VDR): qHTS. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID504855] ChEMBL. No reference
Potency (functional) 56.2341 uM PUBCHEM_BIOASSAY: Inhibitors of USP1/UAF1: Pilot qHTS. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID504878] ChEMBL. No reference

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

Bibliographic References

No literature references available for this target.

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