Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Echinococcus multilocularis | histone lysine methyltransferase setb histone lysine methyltransferase eggless | 0.0031 | 0.035 | 0.0339 |
Echinococcus granulosus | expressed conserved protein | 0.0096 | 0.2337 | 0.2328 |
Echinococcus granulosus | sodium:glucose cotransporter | 0.0038 | 0.0572 | 0.0561 |
Trichomonas vaginalis | proprotein convertase subtilisin/kexin type, putative | 0.0029 | 0.0288 | 0.0366 |
Plasmodium falciparum | superoxide dismutase [Fe] | 0.0078 | 0.1793 | 0.251 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0029 | 0.0288 | 0.0366 |
Trypanosoma cruzi | iron superoxide dismutase, putative | 0.0053 | 0.1034 | 0.5769 |
Leishmania major | heat shock protein 83-1 | 0.0034 | 0.0434 | 0.1339 |
Schistosoma mansoni | hypothetical protein | 0.0042 | 0.0695 | 0.0684 |
Schistosoma mansoni | inositol transporter | 0.0038 | 0.0572 | 0.0561 |
Echinococcus multilocularis | heat shock protein | 0.0034 | 0.0434 | 0.0423 |
Trypanosoma cruzi | heat shock protein 90, putative | 0.002 | 0.0012 | 0.0067 |
Schistosoma mansoni | lipoxygenase | 0.0083 | 0.1948 | 0.1939 |
Schistosoma mansoni | hypothetical protein | 0.0345 | 0.9945 | 0.9944 |
Loa Loa (eye worm) | hypothetical protein | 0.0044 | 0.0744 | 0.0733 |
Schistosoma mansoni | lipoxygenase | 0.0119 | 0.3044 | 0.3035 |
Echinococcus multilocularis | sodium:glucose cotransporter 2 | 0.0038 | 0.0572 | 0.0561 |
Leishmania major | heat shock protein 83-1 | 0.0034 | 0.0434 | 0.1339 |
Trypanosoma brucei | heat shock protein, putative | 0.0034 | 0.0434 | 0.2423 |
Mycobacterium leprae | Probable superoxide dismutase SodA | 0.0078 | 0.1793 | 1 |
Onchocerca volvulus | 0.005 | 0.0933 | 0.1334 | |
Schistosoma mansoni | transcription factor LCR-F1 | 0.0074 | 0.1655 | 0.1645 |
Plasmodium falciparum | endoplasmin, putative | 0.0021 | 0.0036 | 0.0034 |
Entamoeba histolytica | hypothetical protein | 0.0074 | 0.1655 | 0.5835 |
Loa Loa (eye worm) | hypothetical protein | 0.0059 | 0.1197 | 0.1187 |
Onchocerca volvulus | 0.0038 | 0.0572 | 0.0811 | |
Trichomonas vaginalis | heat shock protein, putative | 0.0027 | 0.0225 | 0.0274 |
Brugia malayi | Superoxide dismutase, mitochondrial precursor, putative | 0.0078 | 0.1793 | 0.1783 |
Trypanosoma cruzi | heat shock protein 85, putative | 0.0027 | 0.0225 | 0.1252 |
Trichomonas vaginalis | Clan SB, family S8, subtilisin-like serine peptidase | 0.0035 | 0.0484 | 0.0651 |
Brugia malayi | hypothetical protein | 0.0246 | 0.6905 | 0.6901 |
Echinococcus multilocularis | musashi | 0.0028 | 0.0259 | 0.0247 |
Trypanosoma cruzi | heat shock protein 90, putative | 0.0027 | 0.0225 | 0.1252 |
Echinococcus granulosus | survival motor neuron protein 1 | 0.0246 | 0.6905 | 0.6901 |
Echinococcus granulosus | Niemann Pick C1 protein | 0.0102 | 0.2527 | 0.2518 |
Trichomonas vaginalis | heat shock protein, putative | 0.0027 | 0.0225 | 0.0274 |
Echinococcus multilocularis | Basic leucine zipper (bZIP) transcription | 0.0074 | 0.1655 | 0.1645 |
Trichomonas vaginalis | superoxide dismutase [fe], putative | 0.0078 | 0.1793 | 0.2554 |
Trypanosoma brucei | heat shock protein, putative | 0.0034 | 0.0434 | 0.2423 |
Onchocerca volvulus | Superoxide dismutase [Mn], mitochondrial homolog | 0.0078 | 0.1793 | 0.2579 |
Schistosoma mansoni | high-affinity choline transporter | 0.0347 | 1 | 1 |
Loa Loa (eye worm) | endoplasmin | 0.0034 | 0.0434 | 0.0423 |
Trypanosoma cruzi | superoxide dismutase, putative | 0.0044 | 0.0759 | 0.4231 |
Entamoeba histolytica | Niemann-Pick C1 protein, putative | 0.0102 | 0.2527 | 1 |
Leishmania major | heat shock protein 83-1 | 0.0034 | 0.0434 | 0.1339 |
Leishmania major | heat shock protein 83-1 | 0.0034 | 0.0434 | 0.1339 |
Plasmodium falciparum | heat shock protein 90 | 0.0034 | 0.0434 | 0.0595 |
Onchocerca volvulus | Superoxide dismutase [Mn], mitochondrial homolog | 0.0053 | 0.1034 | 0.1481 |
Onchocerca volvulus | Superoxide dismutase [Mn], mitochondrial homolog | 0.0078 | 0.1793 | 0.2579 |
Plasmodium vivax | superoxide dismutase [Fe], putative | 0.0078 | 0.1793 | 0.251 |
Trypanosoma brucei | superoxide dismutase, putative | 0.0044 | 0.0759 | 0.4231 |
Trichomonas vaginalis | Clan SB, family S8, subtilisin-like serine peptidase | 0.0035 | 0.0484 | 0.0651 |
Schistosoma mansoni | sodium/solute symporter | 0.0038 | 0.0572 | 0.0561 |
Brugia malayi | endoprotease bli-4 precursor | 0.015 | 0.3977 | 0.397 |
Trichomonas vaginalis | heat shock protein, putative | 0.0034 | 0.0434 | 0.0579 |
Trichomonas vaginalis | Clan SB, family S8, subtilisin-like serine peptidase | 0.0035 | 0.0484 | 0.0651 |
Schistosoma mansoni | hypothetical protein | 0.0042 | 0.0695 | 0.0684 |
Onchocerca volvulus | 0.0028 | 0.0259 | 0.0358 | |
Trichomonas vaginalis | conserved hypothetical protein | 0.0044 | 0.0744 | 0.1029 |
Brugia malayi | celfurPC protein | 0.0121 | 0.3092 | 0.3084 |
Toxoplasma gondii | thioredoxin domain-containing protein | 0.0252 | 0.711 | 1 |
Schistosoma mansoni | inositol transporter | 0.0038 | 0.0572 | 0.0561 |
Echinococcus multilocularis | lamin dm0 | 0.0028 | 0.0259 | 0.0247 |
Brugia malayi | heat shock protein 90 | 0.0034 | 0.0434 | 0.0423 |
Brugia malayi | hypothetical protein | 0.0074 | 0.1655 | 0.1645 |
Loa Loa (eye worm) | intermediate filament tail domain-containing protein | 0.0028 | 0.0259 | 0.0247 |
Toxoplasma gondii | superoxide dismutase SOD3 | 0.0078 | 0.1793 | 0.2135 |
Mycobacterium ulcerans | superoxide dismutase [Fe] SodA | 0.0078 | 0.1793 | 1 |
Wolbachia endosymbiont of Brugia malayi | superoxide dismutase, SodA | 0.0078 | 0.1793 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0028 | 0.0243 | 0.0232 |
Leishmania major | heat shock protein 83-1 | 0.0034 | 0.0434 | 0.1339 |
Leishmania major | heat shock protein 83-1 | 0.0034 | 0.0434 | 0.1339 |
Echinococcus multilocularis | geminin | 0.0345 | 0.9945 | 0.9944 |
Echinococcus granulosus | lamin | 0.0028 | 0.0259 | 0.0247 |
Echinococcus multilocularis | tumor protein p63 | 0.0342 | 0.9832 | 0.9832 |
Loa Loa (eye worm) | pre-SET domain-containing protein family protein | 0.0216 | 0.6006 | 0.6001 |
Plasmodium vivax | endoplasmin, putative | 0.0034 | 0.0434 | 0.0595 |
Leishmania major | superoxide dismutase, putative | 0.0044 | 0.0759 | 0.3406 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0029 | 0.0288 | 0.0366 |
Leishmania major | iron superoxide dismutase, putative | 0.0078 | 0.1793 | 1 |
Schistosoma mansoni | cellular tumor antigen P53 | 0.005 | 0.093 | 0.0919 |
Schistosoma mansoni | lamin | 0.0028 | 0.0259 | 0.0247 |
Onchocerca volvulus | 0.005 | 0.093 | 0.1329 | |
Toxoplasma gondii | transporter, solute:sodium symporter (SSS) family protein | 0.0038 | 0.0572 | 0.0328 |
Trypanosoma cruzi | iron superoxide dismutase A, mitochondrial | 0.0078 | 0.1793 | 1 |
Echinococcus granulosus | heat shock protein | 0.0034 | 0.0434 | 0.0423 |
Echinococcus granulosus | furin | 0.015 | 0.3977 | 0.397 |
Schistosoma mansoni | hypothetical protein | 0.0042 | 0.0695 | 0.0684 |
Loa Loa (eye worm) | hypothetical protein | 0.0155 | 0.4142 | 0.4135 |
Echinococcus granulosus | Furin 1 | 0.0035 | 0.0484 | 0.0472 |
Schistosoma mansoni | histone-lysine n-methyltransferase setb1 | 0.0031 | 0.035 | 0.0339 |
Leishmania major | iron superoxide dismutase | 0.0078 | 0.1793 | 1 |
Brugia malayi | Pre-SET motif family protein | 0.0216 | 0.6006 | 0.6001 |
Echinococcus multilocularis | arachidonate 5 lipoxygenase | 0.0119 | 0.3044 | 0.3035 |
Treponema pallidum | heat shock protein 90 | 0.0027 | 0.0225 | 0.5 |
Echinococcus granulosus | intermediate filament protein | 0.0028 | 0.0259 | 0.0247 |
Trichomonas vaginalis | neuroendocrine convertase 2 precursor, putative | 0.0029 | 0.0288 | 0.0366 |
Trypanosoma brucei | iron superoxide dismutase A, mitochondrial | 0.0078 | 0.1793 | 1 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0029 | 0.0288 | 0.0366 |
Echinococcus granulosus | tumor protein p63 | 0.0342 | 0.9832 | 0.9832 |
Schistosoma mansoni | subfamily S8B unassigned peptidase (S08 family) | 0.015 | 0.3977 | 0.397 |
Trypanosoma brucei | iron superoxide dismutase | 0.0078 | 0.1793 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0347 | 1 | 1 |
Plasmodium falciparum | thioredoxin 3 | 0.0252 | 0.711 | 1 |
Trichomonas vaginalis | set domain proteins, putative | 0.0246 | 0.6918 | 1 |
Trichomonas vaginalis | superoxide dismutase [mn], putative | 0.0078 | 0.1793 | 0.2554 |
Trypanosoma cruzi | superoxide dismutase, putative | 0.0044 | 0.0759 | 0.4231 |
Echinococcus multilocularis | survival motor neuron protein 1 | 0.0246 | 0.6905 | 0.6901 |
Schistosoma mansoni | histone-lysine n-methyltransferase setb1 | 0.0031 | 0.035 | 0.0339 |
Echinococcus multilocularis | proprotein convertase subtilisin:kexin type 5 | 0.0091 | 0.2183 | 0.2174 |
Trypanosoma cruzi | superoxide dismutase, putative | 0.0044 | 0.0759 | 0.4231 |
Brugia malayi | Niemann-Pick C1 protein precursor | 0.0102 | 0.2527 | 0.2518 |
Echinococcus granulosus | geminin | 0.0345 | 0.9945 | 0.9944 |
Trypanosoma brucei | heat shock protein, putative | 0.0034 | 0.0434 | 0.2423 |
Trypanosoma brucei | heat shock protein, putative | 0.0034 | 0.0434 | 0.2423 |
Leishmania major | heat shock protein 83-1 | 0.0034 | 0.0434 | 0.1339 |
Echinococcus multilocularis | lamin | 0.0028 | 0.0259 | 0.0247 |
Plasmodium vivax | thioredoxin 3, putative | 0.0252 | 0.711 | 1 |
Trichomonas vaginalis | superoxide dismutase [fe], putative | 0.0078 | 0.1793 | 0.2554 |
Schistosoma mansoni | subfamily S8B non-peptidase homologue (S08 family) | 0.0035 | 0.0484 | 0.0472 |
Trichomonas vaginalis | Clan SB, family S8, subtilisin-like serine peptidase | 0.0035 | 0.0484 | 0.0651 |
Loa Loa (eye worm) | hypothetical protein | 0.0102 | 0.2527 | 0.2518 |
Schistosoma mansoni | hypothetical protein | 0.0029 | 0.0288 | 0.0276 |
Schistosoma mansoni | niemann-pick C1 (NPC1) | 0.0104 | 0.2575 | 0.2566 |
Trypanosoma cruzi | iron superoxide dismutase A, mitochondrial | 0.0078 | 0.1793 | 1 |
Schistosoma mansoni | heat shock protein | 0.0034 | 0.0434 | 0.0423 |
Brugia malayi | neuroendocrine convertase 1 precursor | 0.0094 | 0.2277 | 0.2268 |
Trichomonas vaginalis | leucine-rich repeat protein, BspA family | 0.0029 | 0.0288 | 0.0366 |
Schistosoma mansoni | superoxide dismutase [mn] | 0.0078 | 0.1793 | 0.1783 |
Trypanosoma cruzi | iron superoxide dismutase, putative | 0.0078 | 0.1793 | 1 |
Loa Loa (eye worm) | endoprotease bli-4 | 0.015 | 0.3977 | 0.397 |
Brugia malayi | Iron-sulfur cluster assembly accessory protein | 0.005 | 0.0933 | 0.0923 |
Trichomonas vaginalis | Clan SB, family S8, subtilisin-like serine peptidase | 0.0091 | 0.2183 | 0.312 |
Leishmania major | heat shock protein 83-1 | 0.0034 | 0.0434 | 0.1339 |
Onchocerca volvulus | 0.0028 | 0.0259 | 0.0358 | |
Entamoeba histolytica | hypothetical protein | 0.0074 | 0.1655 | 0.5835 |
Leishmania major | heat shock protein 83-1 | 0.0034 | 0.0434 | 0.1339 |
Echinococcus multilocularis | protein dispatched 1 | 0.005 | 0.0933 | 0.0922 |
Toxoplasma gondii | superoxide dismutase SOD2 | 0.0078 | 0.1793 | 0.2135 |
Loa Loa (eye worm) | hypothetical protein | 0.015 | 0.3977 | 0.397 |
Leishmania major | superoxide dismutase, putative | 0.0044 | 0.0759 | 0.3406 |
Toxoplasma gondii | heat shock protein 90, putative | 0.0034 | 0.0434 | 0.0124 |
Loa Loa (eye worm) | hypothetical protein | 0.0031 | 0.035 | 0.0339 |
Leishmania major | heat shock protein 83-1 | 0.0034 | 0.0434 | 0.1339 |
Toxoplasma gondii | heat shock protein HSP90 | 0.0034 | 0.0434 | 0.0124 |
Trypanosoma brucei | heat shock protein, putative | 0.0034 | 0.0434 | 0.2423 |
Trypanosoma cruzi | heat shock protein 85, putative | 0.0034 | 0.0434 | 0.2423 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0029 | 0.0288 | 0.0366 |
Schistosoma mansoni | hypothetical protein | 0.005 | 0.0933 | 0.0923 |
Echinococcus multilocularis | histone lysine N methyltransferase SETMAR | 0.0031 | 0.035 | 0.0339 |
Schistosoma mansoni | hypothetical protein | 0.0074 | 0.1655 | 0.1645 |
Leishmania major | heat shock protein 83-1 | 0.0034 | 0.0434 | 0.1339 |
Echinococcus granulosus | sodium coupled monocarboxylate transporter 1 | 0.0038 | 0.0572 | 0.0561 |
Plasmodium vivax | SET domain protein, putative | 0.0031 | 0.035 | 0.0477 |
Giardia lamblia | High cysteine membrane protein Group 2 | 0.0056 | 0.1103 | 1 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0029 | 0.0288 | 0.0366 |
Echinococcus multilocularis | expressed conserved protein | 0.0096 | 0.2337 | 0.2328 |
Brugia malayi | CHE-14 protein | 0.0044 | 0.0744 | 0.0733 |
Brugia malayi | Sodium:solute symporter family protein | 0.0038 | 0.0572 | 0.0561 |
Echinococcus multilocularis | 0.0121 | 0.3092 | 0.3084 | |
Loa Loa (eye worm) | hypothetical protein | 0.0078 | 0.1793 | 0.1783 |
Echinococcus granulosus | Protein patched homolog 1 | 0.0044 | 0.0744 | 0.0733 |
Schistosoma mansoni | heat shock protein | 0.0034 | 0.0434 | 0.0423 |
Echinococcus granulosus | high affinity choline transporter 1 | 0.0347 | 1 | 1 |
Echinococcus multilocularis | manganese superoxide dismutase | 0.0078 | 0.1793 | 0.1783 |
Trypanosoma cruzi | heat shock protein 85, putative | 0.0034 | 0.0434 | 0.2423 |
Toxoplasma gondii | superoxide dismutase | 0.0078 | 0.1793 | 0.2135 |
Echinococcus multilocularis | Niemann Pick C1 protein | 0.0102 | 0.2527 | 0.2518 |
Schistosoma mansoni | furin-1 (S08 family) | 0.0065 | 0.1393 | 0.1382 |
Loa Loa (eye worm) | intermediate filament protein | 0.0028 | 0.0259 | 0.0247 |
Echinococcus multilocularis | sterol regulatory element binding protein | 0.0044 | 0.0744 | 0.0733 |
Echinococcus multilocularis | muscleblind protein 1 | 0.0155 | 0.4142 | 0.4135 |
Brugia malayi | Pre-SET motif family protein | 0.0031 | 0.035 | 0.0339 |
Echinococcus granulosus | Basic leucine zipper bZIP transcription | 0.0074 | 0.1655 | 0.1645 |
Loa Loa (eye worm) | hypothetical protein | 0.0054 | 0.1045 | 0.1035 |
Trypanosoma cruzi | iron superoxide dismutase, putative | 0.0078 | 0.1793 | 1 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0029 | 0.0288 | 0.0366 |
Trypanosoma cruzi | heat shock protein 90, putative | 0.0034 | 0.0434 | 0.2423 |
Echinococcus multilocularis | endoplasmin | 0.0027 | 0.0225 | 0.0213 |
Leishmania major | heat shock protein 83-1 | 0.0034 | 0.0434 | 0.1339 |
Brugia malayi | Endoplasmin precursor | 0.0034 | 0.0434 | 0.0423 |
Echinococcus granulosus | solute carrier family 5 | 0.0038 | 0.0572 | 0.0561 |
Echinococcus granulosus | muscleblind protein | 0.0155 | 0.4142 | 0.4135 |
Schistosoma mansoni | histone-lysine n-methyltransferase suv9 | 0.0031 | 0.035 | 0.0339 |
Onchocerca volvulus | 0.0031 | 0.035 | 0.049 | |
Trichomonas vaginalis | conserved hypothetical protein | 0.0029 | 0.0288 | 0.0366 |
Echinococcus multilocularis | sodium coupled monocarboxylate transporter 1 | 0.0038 | 0.0572 | 0.0561 |
Echinococcus multilocularis | Niemann Pick C1 protein | 0.0146 | 0.3867 | 0.3859 |
Trypanosoma cruzi | Heat shock protein 83, putative | 0.0034 | 0.0434 | 0.2423 |
Brugia malayi | intermediate filament protein | 0.0028 | 0.0259 | 0.0247 |
Echinococcus multilocularis | neuroendocrine convertase 2 | 0.0094 | 0.2277 | 0.2268 |
Trypanosoma brucei | iron superoxide dismutase | 0.0078 | 0.1793 | 1 |
Echinococcus multilocularis | protein patched | 0.0044 | 0.0744 | 0.0733 |
Leishmania major | heat shock protein 83-1 | 0.0034 | 0.0434 | 0.1339 |
Schistosoma mansoni | hypothetical protein | 0.0042 | 0.0695 | 0.0684 |
Schistosoma mansoni | patched 1 | 0.0044 | 0.0744 | 0.0733 |
Trichomonas vaginalis | iron superoxide dismutase A, putative | 0.0078 | 0.1793 | 0.2554 |
Loa Loa (eye worm) | hypothetical protein | 0.0246 | 0.6905 | 0.6901 |
Trypanosoma brucei | heat shock protein, putative | 0.0034 | 0.0434 | 0.2423 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0029 | 0.0288 | 0.0366 |
Trypanosoma brucei | heat shock protein, putative | 0.0034 | 0.0434 | 0.2423 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0029 | 0.0288 | 0.0366 |
Brugia malayi | Muscleblind-like protein | 0.0155 | 0.4142 | 0.4135 |
Echinococcus granulosus | heat shock protein 90 | 0.0034 | 0.0434 | 0.0423 |
Entamoeba histolytica | hypothetical protein | 0.0074 | 0.1655 | 0.5835 |
Trichomonas vaginalis | superoxide dismutase, putative | 0.0078 | 0.1793 | 0.2554 |
Echinococcus granulosus | neuroendocrine convertase 2 | 0.0094 | 0.2277 | 0.2268 |
Echinococcus granulosus | lamin dm0 | 0.0028 | 0.0259 | 0.0247 |
Leishmania major | heat shock protein 83-1 | 0.0034 | 0.0434 | 0.1339 |
Echinococcus granulosus | manganese superoxide dismutase | 0.0078 | 0.1793 | 0.1783 |
Mycobacterium tuberculosis | Superoxide dismutase [FE] SodA | 0.0078 | 0.1793 | 1 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0029 | 0.0288 | 0.0366 |
Echinococcus multilocularis | heat shock protein 90 | 0.0027 | 0.0225 | 0.0213 |
Leishmania major | heat shock protein 83-1 | 0.0034 | 0.0434 | 0.1339 |
Loa Loa (eye worm) | proprotein convertase 2 | 0.0035 | 0.0484 | 0.0472 |
Schistosoma mansoni | histone-lysine n-methyltransferase setb1 | 0.0031 | 0.035 | 0.0339 |
Schistosoma mansoni | hypothetical protein | 0.0345 | 0.9945 | 0.9944 |
Echinococcus multilocularis | high affinity choline transporter 1 | 0.0347 | 1 | 1 |
Schistosoma mansoni | survival motor neuron protein | 0.005 | 0.0933 | 0.0923 |
Trypanosoma brucei | iron superoxide dismutase C, mitochondrial | 0.0044 | 0.0759 | 0.4231 |
Giardia lamblia | Heat shock protein HSP 90-alpha | 0.0034 | 0.0434 | 0.2391 |
Echinococcus granulosus | endoplasmin | 0.0027 | 0.0225 | 0.0213 |
Entamoeba histolytica | hypothetical protein | 0.0074 | 0.1655 | 0.5835 |
Trichomonas vaginalis | heat shock protein, putative | 0.0027 | 0.0225 | 0.0274 |
Leishmania major | heat shock protein 83-1 | 0.0034 | 0.0434 | 0.1339 |
Loa Loa (eye worm) | heat shock protein 90 | 0.0034 | 0.0434 | 0.0423 |
Trypanosoma brucei | heat shock protein, putative | 0.0034 | 0.0434 | 0.2423 |
Trypanosoma brucei | heat shock protein 90, putative | 0.0034 | 0.0434 | 0.2423 |
Trypanosoma cruzi | heat shock protein 85, putative | 0.0034 | 0.0434 | 0.2423 |
Trypanosoma brucei | Heat shock protein 83, putative | 0.0034 | 0.0434 | 0.2423 |
Loa Loa (eye worm) | abnormal chemotaxis protein 14 | 0.0044 | 0.0744 | 0.0733 |
Brugia malayi | Cytochrome P450 family protein | 0.0026 | 0.0211 | 0.0199 |
Echinococcus granulosus | sterol regulatory element binding protein | 0.0044 | 0.0744 | 0.0733 |
Leishmania major | heat shock protein 83-1 | 0.0034 | 0.0434 | 0.1339 |
Schistosoma mansoni | lamin | 0.0028 | 0.0259 | 0.0247 |
Echinococcus multilocularis | sodium:myo inositol cotransporter | 0.0038 | 0.0572 | 0.0561 |
Loa Loa (eye worm) | hypothetical protein | 0.0038 | 0.0572 | 0.0561 |
Brugia malayi | Intermediate filament tail domain containing protein | 0.0028 | 0.0259 | 0.0247 |
Loa Loa (eye worm) | hypothetical protein | 0.005 | 0.093 | 0.0919 |
Leishmania major | iron superoxide dismutase, putative | 0.0078 | 0.1793 | 1 |
Echinococcus granulosus | heat shock protein heat shock protein 90 alpha | 0.0027 | 0.0225 | 0.0213 |
Loa Loa (eye worm) | hypothetical protein | 0.0155 | 0.4142 | 0.4135 |
Trichomonas vaginalis | superoxide dismutase [fe], putative | 0.0078 | 0.1793 | 0.2554 |
Echinococcus granulosus | Niemann Pick C1 protein | 0.0146 | 0.3867 | 0.3859 |
Echinococcus granulosus | sodium:glucose cotransporter 2 | 0.0038 | 0.0572 | 0.0561 |
Trypanosoma cruzi | superoxide dismutase, putative | 0.0044 | 0.0759 | 0.4231 |
Plasmodium vivax | superoxide dismutase [Fe], putative | 0.0044 | 0.0759 | 0.1052 |
Echinococcus granulosus | histone lysine methyltransferase setb | 0.0031 | 0.035 | 0.0339 |
Giardia lamblia | Furin precursor putative serine protease | 0.0029 | 0.0288 | 0.0724 |
Echinococcus granulosus | sodium:myo inositol cotransporter | 0.0038 | 0.0572 | 0.0561 |
Trichomonas vaginalis | Clan SB, family S8, subtilisin-like serine peptidase | 0.0035 | 0.0484 | 0.0651 |
Trichomonas vaginalis | Clan SB, family S8, subtilisin-like serine peptidase | 0.0091 | 0.2183 | 0.312 |
Loa Loa (eye worm) | cytochrome P450 family protein | 0.0026 | 0.0211 | 0.0199 |
Echinococcus granulosus | arachidonate 5 lipoxygenase | 0.0119 | 0.3044 | 0.3035 |
Echinococcus granulosus | proprotein convertase subtilisin:kexin type 5 | 0.0091 | 0.2183 | 0.2174 |
Schistosoma mansoni | intermediate filament proteins | 0.0028 | 0.0259 | 0.0247 |
Echinococcus granulosus | heat shock protein 90 | 0.0027 | 0.0225 | 0.0213 |
Schistosoma mansoni | endoplasmin | 0.0034 | 0.0434 | 0.0423 |
Schistosoma mansoni | endoplasmin | 0.0034 | 0.0434 | 0.0423 |
Brugia malayi | proprotein convertase 2 | 0.0094 | 0.2277 | 0.2268 |
Loa Loa (eye worm) | hypothetical protein | 0.0028 | 0.0259 | 0.0247 |
Trichomonas vaginalis | hypothetical protein | 0.0029 | 0.0288 | 0.0366 |
Echinococcus multilocularis | Furin 1 | 0.0035 | 0.0484 | 0.0472 |
Echinococcus granulosus | 5'partial|histone lysine N methyltransferase SETDB2 | 0.003 | 0.0316 | 0.0304 |
Plasmodium falciparum | superoxide dismutase [Fe] | 0.0044 | 0.0759 | 0.1052 |
Entamoeba histolytica | iron-containing superoxide dismutase | 0.0078 | 0.1793 | 0.6495 |
Echinococcus multilocularis | solute carrier family 5 | 0.0038 | 0.0572 | 0.0561 |
Echinococcus multilocularis | muscleblind protein | 0.0155 | 0.4142 | 0.4135 |
Trichomonas vaginalis | Clan SB, family S8, subtilisin-like serine peptidase | 0.0035 | 0.0484 | 0.0651 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0029 | 0.0288 | 0.0366 |
Trypanosoma brucei | heat shock protein 90, putative | 0.0034 | 0.0434 | 0.2423 |
Trichomonas vaginalis | superoxide dismutase, putative | 0.0078 | 0.1793 | 0.2554 |
Plasmodium vivax | heat shock protein 86, putative | 0.0034 | 0.0434 | 0.0595 |
Trypanosoma cruzi | iron superoxide dismutase, putative | 0.0078 | 0.1793 | 1 |
Echinococcus multilocularis | heat shock protein 90 | 0.0034 | 0.0434 | 0.0423 |
Onchocerca volvulus | 0.0246 | 0.6918 | 1 | |
Chlamydia trachomatis | superoxide dismutase | 0.0078 | 0.1793 | 0.5 |
Activity type | Activity value | Assay description | Source | Reference |
---|---|---|---|---|
IC50 (functional) | = 13.4 uM | Compound was tested for inhibition of MAdCAM-1/alpha4 beta7 mediated cell adhesion to T-cell lymphoma, HUT78 cells | ChEMBL. | No reference |
Inhibition (functional) | = 13.4 % | Inhibition of MAdCAM-1/alpha4 beta7-mediated cell adhesion to T-cell lymphoma, HUT78 cells at 500 microM. | ChEMBL. | No reference |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.