Detailed information for compound 1366148

Basic information

Technical information
  • TDR Targets ID: 1366148
  • Name: 4-[(4-nitrophenyl)carbamoylamino]benzoic acid
  • MW: 301.254 | Formula: C14H11N3O5
  • H donors: 3 H acceptors: 5 LogP: 1.84 Rotable bonds: 6
    Rule of 5 violations (Lipinski): 1
  • SMILES: O=C(Nc1ccc(cc1)C(=O)O)Nc1ccc(cc1)[N+](=O)[O-]
  • InChi: 1S/C14H11N3O5/c18-13(19)9-1-3-10(4-2-9)15-14(20)16-11-5-7-12(8-6-11)17(21)22/h1-8H,(H,18,19)(H2,15,16,20)
  • InChiKey: WAMAJEDCQWPNLF-UHFFFAOYSA-N  


Substructure search Similarity search

Network

Hover on a compound node to display the structore

Synonyms

  • 4-[[[(4-nitrophenyl)amino]-oxomethyl]amino]benzoic acid
  • 4-[3-(4-Nitro-phenyl)-ureido]-benzoic acid
  • BAS 01156593
  • STK331471

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0017 0.0075 0.0075
Mycobacterium tuberculosis Probable lipase LipD 0.0038 0.0759 0.0943
Onchocerca volvulus 0.0038 0.0759 0.7383
Echinococcus multilocularis tyrosine protein kinase Blk 0.0033 0.0596 0.0596
Echinococcus multilocularis proto oncogene tyrosine protein kinase LCK 0.0037 0.071 0.071
Loa Loa (eye worm) carboxylesterase 0.0027 0.0411 0.0411
Entamoeba histolytica hypothetical protein 0.0038 0.0758 0.1165
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0038 0.0759 0.1439
Schistosoma mansoni transcription factor LCR-F1 0.0038 0.0758 0.1437
Echinococcus multilocularis CD36 class B scavenger receptor 0.0042 0.0882 0.0882
Echinococcus granulosus CD36 class B scavenger receptor 0.0042 0.0882 0.0882
Loa Loa (eye worm) hypothetical protein 0.0027 0.0411 0.0411
Echinococcus multilocularis CD36 class B scavenger receptor 0.0042 0.0882 0.0882
Echinococcus granulosus GPCR family 2 0.0017 0.0075 0.0075
Loa Loa (eye worm) hypothetical protein 0.0042 0.0882 0.0882
Loa Loa (eye worm) hypothetical protein 0.0038 0.0759 0.0759
Schistosoma mansoni family S9 non-peptidase homologue (S09 family) 0.0027 0.0411 0.0779
Loa Loa (eye worm) hypothetical protein 0.0158 0.4593 0.4593
Mycobacterium leprae Probable lipase LipE 0.0038 0.0759 0.5
Loa Loa (eye worm) TK protein kinase 0.0029 0.0479 0.0479
Echinococcus multilocularis isocitrate dehydrogenase 2 (NADP+) 0.0017 0.0075 0.0075
Onchocerca volvulus 0.0038 0.0759 0.7383
Echinococcus multilocularis Niemann Pick C1 protein 0.0104 0.2871 0.2871
Loa Loa (eye worm) TK protein kinase 0.0033 0.0596 0.0596
Entamoeba histolytica hypothetical protein 0.0038 0.0758 0.1165
Mycobacterium tuberculosis Conserved protein 0.0038 0.0759 0.0943
Echinococcus granulosus Protein patched homolog 1 0.0045 0.097 0.097
Mycobacterium tuberculosis Probable lipase LipE 0.0038 0.0759 0.0943
Schistosoma mansoni hypothetical protein 0.0017 0.0075 0.0141
Schistosoma mansoni acetylcholinesterase 0.0027 0.0411 0.0779
Mycobacterium tuberculosis Conserved protein 0.0038 0.0759 0.0943
Trichomonas vaginalis penicillin-binding protein, putative 0.0038 0.0759 0.6221
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.0038 0.0759 0.0943
Trypanosoma cruzi hypothetical protein, conserved 0.0038 0.0759 1
Loa Loa (eye worm) hypothetical protein 0.0027 0.0411 0.0411
Loa Loa (eye worm) zinc finger protein 0.0327 1 1
Echinococcus granulosus Niemann Pick C1 protein 0.0104 0.2871 0.2871
Brugia malayi Latrophilin receptor protein 2 0.0017 0.0075 0.0075
Echinococcus multilocularis carboxylesterase 5A 0.0161 0.4689 0.4689
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0037 0.071 0.071
Loa Loa (eye worm) MH2 domain-containing protein 0.0126 0.3579 0.3579
Entamoeba histolytica hypothetical protein 0.0038 0.0758 0.1165
Echinococcus multilocularis expressed conserved protein 0.0098 0.2669 0.2669
Echinococcus multilocularis para nitrobenzyl esterase 0.0027 0.0411 0.0411
Mycobacterium ulcerans hypothetical protein 0.0038 0.0759 1
Echinococcus multilocularis GPCR, family 2 0.0017 0.0075 0.0075
Echinococcus multilocularis beta LACTamase domain containing family member 0.0038 0.0759 0.0759
Loa Loa (eye worm) hypothetical protein 0.0027 0.0411 0.0411
Echinococcus granulosus acetylcholinesterase 0.0161 0.4689 0.4689
Schistosoma mansoni hypothetical protein 0.0017 0.0075 0.0141
Toxoplasma gondii ABC1 family protein 0.0038 0.0759 1
Brugia malayi beta-lactamase family protein 0.0038 0.0759 0.0759
Mycobacterium tuberculosis Probable hydrolase 0.0038 0.0759 0.0943
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0033 0.0596 0.0596
Echinococcus granulosus neuroligin 0.0027 0.0411 0.0411
Echinococcus granulosus tyrosine protein kinase Lyn 0.0037 0.071 0.071
Schistosoma mansoni tyrosine kinase 0.0037 0.071 0.1347
Mycobacterium tuberculosis Carboxylesterase LipT 0.0027 0.0411 0.0463
Brugia malayi MH2 domain containing protein 0.0126 0.3579 0.3579
Brugia malayi Muscleblind-like protein 0.0158 0.4593 0.4593
Echinococcus granulosus para nitrobenzyl esterase 0.0027 0.0411 0.0411
Loa Loa (eye worm) hypothetical protein 0.0158 0.4593 0.4593
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0017 0.0075 0.0075
Echinococcus granulosus tyrosine protein kinase Src64B 0.0037 0.071 0.071
Echinococcus granulosus Niemann Pick C1 protein 0.0149 0.43 0.43
Brugia malayi Carboxylesterase family protein 0.0161 0.4689 0.4689
Mycobacterium ulcerans lipase LipD 0.0038 0.0759 1
Echinococcus granulosus tyrosine protein kinase Fyn 0.0037 0.071 0.071
Brugia malayi Isocitrate dehydrogenase 0.0017 0.0075 0.0075
Loa Loa (eye worm) hypothetical protein 0.0027 0.0411 0.0411
Echinococcus granulosus CD36 class B scavenger receptor 0.0042 0.0882 0.0882
Schistosoma mansoni family S9 non-peptidase homologue (S09 family) 0.0027 0.0411 0.0779
Echinococcus granulosus 3'partial|tyrosine protein kinase Fgr 0.0037 0.071 0.071
Echinococcus granulosus acetylcholinesterase 0.0161 0.4689 0.4689
Schistosoma mansoni patched 1 0.0045 0.097 0.184
Schistosoma mansoni hypothetical protein 0.0017 0.0075 0.0141
Loa Loa (eye worm) hypothetical protein 0.0027 0.0411 0.0411
Loa Loa (eye worm) abnormal chemotaxis protein 14 0.0045 0.097 0.097
Loa Loa (eye worm) hypothetical protein 0.0017 0.0075 0.0075
Schistosoma mansoni hypothetical protein 0.0179 0.5272 1
Loa Loa (eye worm) hypothetical protein 0.0038 0.0759 0.0759
Echinococcus granulosus lysosome membrane protein 2 0.0042 0.0882 0.0882
Loa Loa (eye worm) carboxylesterase 0.0027 0.0411 0.0411
Trichomonas vaginalis D-aminoacylase, putative 0.0038 0.0759 0.6221
Loa Loa (eye worm) hypothetical protein 0.0055 0.1291 0.1291
Brugia malayi Carboxylesterase family protein 0.0027 0.0411 0.0411
Loa Loa (eye worm) hypothetical protein 0.0161 0.4689 0.4689
Brugia malayi protein-tyrosine kinase 0.0033 0.0596 0.0596
Echinococcus granulosus tyrosine protein kinase HCK 0.0029 0.0479 0.0479
Echinococcus multilocularis tyrosine protein kinase HCK 0.0029 0.0479 0.0479
Brugia malayi latrophilin 2 splice variant baaae 0.0036 0.0694 0.0694
Mycobacterium ulcerans esterase/lipase LipP 0.0038 0.0759 1
Trichomonas vaginalis D-aminoacylase, putative 0.0038 0.0759 0.6221
Schistosoma mansoni hypothetical protein 0.0043 0.0918 0.1742
Loa Loa (eye worm) hypothetical protein 0.0042 0.0882 0.0882
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0038 0.0759 0.1439
Echinococcus granulosus tyrosine kinase|tyrosine protein kinase Fyn 0.0033 0.0596 0.0596
Echinococcus multilocularis zinc finger transcription factor gli2 0.0327 1 1
Echinococcus granulosus tyrosine protein kinase Src42A 0.0032 0.0563 0.0563
Echinococcus multilocularis CD36 class B scavenger receptor 0.0042 0.0882 0.0882
Echinococcus granulosus tyrosine protein kinase Fyn 0.0037 0.071 0.071
Echinococcus granulosus tyrosine protein kinase Blk 0.0033 0.0596 0.0596
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0038 0.0758 0.0758
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0017 0.0075 0.0075
Echinococcus multilocularis isocitrate dehydrogenase 0.0017 0.0075 0.0075
Brugia malayi Carboxylesterase family protein 0.0027 0.0411 0.0411
Echinococcus multilocularis geminin 0.0179 0.5272 0.5272
Echinococcus multilocularis acetylcholinesterase 0.0161 0.4689 0.4689
Loa Loa (eye worm) hypothetical protein 0.0104 0.2871 0.2871
Loa Loa (eye worm) hypothetical protein 0.0027 0.0411 0.0411
Loa Loa (eye worm) hypothetical protein 0.0053 0.1227 0.1227
Echinococcus multilocularis tyrosine protein kinase lyn lyn a protein tyrosine kinase lymphocyte specific protein tyrosine kinase 0.0037 0.071 0.071
Schistosoma mansoni niemann-pick C1 (NPC1) 0.0106 0.2922 0.5543
Trypanosoma brucei hypothetical protein, conserved 0.0038 0.0759 1
Brugia malayi Carboxylesterase family protein 0.0161 0.4689 0.4689
Schistosoma mansoni hypothetical protein 0.0017 0.0075 0.0141
Brugia malayi hypothetical protein 0.0042 0.0882 0.0882
Schistosoma mansoni CD36-like class B scavenger receptor 0.0042 0.0882 0.1673
Echinococcus granulosus CD36 class B scavenger receptor 0.0042 0.0882 0.0882
Brugia malayi CD36 family protein 0.0042 0.0882 0.0882
Schistosoma mansoni hypothetical protein 0.0043 0.0918 0.1742
Mycobacterium tuberculosis Probable conserved lipoprotein 0.0038 0.0759 0.0943
Trichomonas vaginalis penicillin-binding protein, putative 0.0038 0.0759 0.6221
Brugia malayi beta-lactamase 0.0038 0.0759 0.0759
Onchocerca volvulus 0.0038 0.0759 0.7383
Brugia malayi SRC-1 0.0037 0.071 0.071
Echinococcus multilocularis Niemann Pick C1 protein 0.0149 0.43 0.43
Echinococcus granulosus proto oncogene tyrosine protein kinase LCK 0.0037 0.071 0.071
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0037 0.071 0.071
Leishmania major hypothetical protein, conserved 0.0038 0.0759 1
Loa Loa (eye worm) transcription factor SMAD2 0.0126 0.3579 0.3579
Entamoeba histolytica hypothetical protein 0.0038 0.0758 0.1165
Echinococcus granulosus geminin 0.0179 0.5272 0.5272
Echinococcus multilocularis sterol regulatory element binding protein 0.0045 0.097 0.097
Schistosoma mansoni family S9 non-peptidase homologue (S09 family) 0.0027 0.0411 0.0779
Echinococcus granulosus family S9 non peptidase ue S09 family 0.0027 0.0411 0.0411
Echinococcus multilocularis tyrosine protein kinase Src64B 0.0037 0.071 0.071
Mycobacterium tuberculosis POSSIBLE PARA-NITROBENZYL ESTERASE (FRAGMENT) 0.0027 0.0411 0.0463
Loa Loa (eye worm) isocitrate dehydrogenase 0.0017 0.0075 0.0075
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0053 0.1227 0.1227
Echinococcus multilocularis lysosome membrane protein 2 0.0042 0.0882 0.0882
Loa Loa (eye worm) beta-lactamase 0.0038 0.0759 0.0759
Loa Loa (eye worm) hypothetical protein 0.0042 0.0882 0.0882
Schistosoma mansoni cd36 antigen 0.0042 0.0882 0.1673
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0017 0.0075 0.0075
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0053 0.1227 0.1227
Echinococcus granulosus CD36 class B scavenger receptor 0.0042 0.0882 0.0882
Plasmodium vivax hypothetical protein, conserved 0.0038 0.0759 1
Echinococcus granulosus NADP dependent isocitrate dehydrogenase 0.0017 0.0075 0.0075
Trypanosoma cruzi hypothetical protein, conserved 0.0038 0.0759 1
Schistosoma mansoni family S9 non-peptidase homologue (S09 family) 0.0161 0.4689 0.8895
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0017 0.0075 0.0075
Brugia malayi Calcitonin receptor-like protein seb-1 0.0053 0.1227 0.1227
Mycobacterium tuberculosis Possible penicillin-binding protein 0.0243 0.732 1
Schistosoma mansoni scavenger receptor class B type-2 (sr-B2) 0.0042 0.0882 0.1673
Echinococcus granulosus expressed conserved protein 0.0098 0.2669 0.2669
Trichomonas vaginalis D-aminoacylase, putative 0.0038 0.0759 0.6221
Mycobacterium tuberculosis Conserved protein 0.0038 0.0759 0.0943
Entamoeba histolytica Niemann-Pick C1 protein, putative 0.0104 0.2871 1
Schistosoma mansoni NADP-specific isocitrate dehydrogenase 0.0017 0.0075 0.0143
Trichomonas vaginalis esterase, putative 0.0038 0.0759 0.6221
Brugia malayi hypothetical protein 0.0042 0.0882 0.0882
Mycobacterium leprae conserved hypothetical protein 0.0038 0.0759 0.5
Echinococcus multilocularis tyrosine protein kinase Fgr 0.0037 0.071 0.071
Schistosoma mansoni hypothetical protein 0.0043 0.0918 0.1742
Echinococcus granulosus tyrosine kinase 0.0033 0.0596 0.0596
Schistosoma mansoni gliotactin 0.0027 0.0411 0.0779
Loa Loa (eye worm) hypothetical protein 0.0045 0.097 0.097
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0017 0.0075 0.0075
Loa Loa (eye worm) hypothetical protein 0.0038 0.0759 0.0759
Brugia malayi hypothetical protein 0.0038 0.0758 0.0758
Echinococcus multilocularis tyrosine protein kinase Src42A 0.0032 0.0563 0.0563
Echinococcus granulosus CD36 class B scavenger receptor 0.0042 0.0882 0.0882
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0017 0.0075 0.0075
Loa Loa (eye worm) hypothetical protein 0.0038 0.0759 0.0759
Echinococcus granulosus beta LACTamase domain containing family member 0.0038 0.0759 0.0759
Echinococcus granulosus tyrosine protein kinase Src42A 0.0037 0.071 0.071
Echinococcus granulosus tyrosine protein kinase Fyn 0.0037 0.071 0.071
Mycobacterium tuberculosis Probable esterase LipL 0.0038 0.0759 0.0943
Loa Loa (eye worm) hypothetical protein 0.0038 0.0759 0.0759
Echinococcus multilocularis tyrosine protein kinase Srms 0.0033 0.0596 0.0596
Echinococcus multilocularis CD36 class B scavenger receptor 0.0042 0.0882 0.0882
Echinococcus multilocularis neuroligin 0.0027 0.0411 0.0411
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0038 0.0758 0.0758
Schistosoma mansoni neuroligin 3 (S09 family) 0.0027 0.0411 0.0779
Echinococcus granulosus sterol regulatory element binding protein 0.0045 0.097 0.097
Loa Loa (eye worm) hypothetical protein 0.0042 0.0882 0.0882
Loa Loa (eye worm) SRC-1 0.0037 0.071 0.071
Mycobacterium ulcerans beta-lactamase 0.0038 0.0759 1
Loa Loa (eye worm) hypothetical protein 0.0038 0.0759 0.0759
Echinococcus multilocularis family S9 non peptidase ue (S09 family) 0.0027 0.0411 0.0411
Loa Loa (eye worm) carboxylesterase 0.0161 0.4689 0.4689
Brugia malayi Carboxylesterase family protein 0.0027 0.0411 0.0411
Loa Loa (eye worm) hypothetical protein 0.0036 0.0694 0.0694
Echinococcus granulosus carboxylesterase 5A 0.0161 0.4689 0.4689
Schistosoma mansoni wnt related 0.0014 0.000000000097214 0.0000000001844
Schistosoma mansoni CD36-like class B scavenger receptor 0.0042 0.0882 0.1673
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0038 0.0759 0.0759
Brugia malayi CHE-14 protein 0.0045 0.097 0.097
Echinococcus multilocularis acetylcholinesterase 0.0161 0.4689 0.4689
Schistosoma mansoni hypothetical protein 0.0179 0.5272 1
Brugia malayi Carboxylesterase family protein 0.0027 0.0411 0.0411
Echinococcus granulosus zinc finger transcription factor gli2 0.0327 1 1
Schistosoma mansoni hypothetical protein 0.0043 0.0918 0.1742
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0017 0.0075 0.0075
Echinococcus multilocularis tyrosine protein kinase lyn tyrosine protein kinase blk 0.0037 0.071 0.071
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0038 0.0759 0.0759
Trichomonas vaginalis conserved hypothetical protein 0.0045 0.097 1
Brugia malayi hypothetical protein 0.0027 0.0411 0.0411
Schistosoma mansoni tyrosine kinase 0.0037 0.071 0.1347
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.0038 0.0759 1
Echinococcus multilocularis muscleblind protein 1 0.0158 0.4593 0.4593
Brugia malayi beta-lactamase family protein 0.0038 0.0759 0.0759
Onchocerca volvulus Lysosome membrane protein 2 homolog 0.0042 0.0882 1
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0037 0.071 0.071
Loa Loa (eye worm) acetylcholinesterase 1 0.0161 0.4689 0.4689
Loa Loa (eye worm) hypothetical protein 0.0027 0.0411 0.0411
Schistosoma mansoni hypothetical protein 0.0038 0.0758 0.1437
Loa Loa (eye worm) hypothetical protein 0.0042 0.0882 0.0882
Mycobacterium tuberculosis POSSIBLE PARA-NITROBENZYL ESTERASE (FRAGMENT) 0.0027 0.0411 0.0463
Brugia malayi Niemann-Pick C1 protein precursor 0.0104 0.2871 0.2871
Echinococcus multilocularis CD36 class B scavenger receptor 0.0042 0.0882 0.0882
Loa Loa (eye worm) hypothetical protein 0.0042 0.0882 0.0882
Loa Loa (eye worm) hypothetical protein 0.0161 0.4689 0.4689
Echinococcus multilocularis BC026374 protein (S09 family) 0.0027 0.0411 0.0411
Schistosoma mansoni hypothetical protein 0.0036 0.0694 0.1316
Echinococcus granulosus muscleblind protein 0.0158 0.4593 0.4593
Echinococcus multilocularis muscleblind protein 0.0158 0.4593 0.4593
Loa Loa (eye worm) latrophilin receptor protein 2 0.0017 0.0075 0.0075
Echinococcus multilocularis tyrosine protein kinase Src42A 0.0037 0.071 0.071
Plasmodium falciparum isocitrate dehydrogenase [NADP], mitochondrial 0.0017 0.0075 0.5
Echinococcus multilocularis protein patched 0.0045 0.097 0.097
Brugia malayi isocitrate dehydrogenase 0.0017 0.0075 0.0075
Schistosoma mansoni BC026374 protein (S09 family) 0.0027 0.0411 0.0779
Echinococcus granulosus BC026374 protein S09 family 0.0027 0.0411 0.0411
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.0038 0.0759 0.0943
Echinococcus multilocularis protein dispatched 1 0.0051 0.1172 0.1172

Activities

Activity type Activity value Assay description Source Reference
AbsAC1 (functional) = 5.57 uM PubChem BioAssay. Small Molecule Inhibitors of FGF22-Mediated Excitatory Synaptogenesis & Epilepsy Measured in Biochemical System Using RT-PCR - 7012-01_Inhibitor_Dose_CherryPick_Activity. (Class of assay: confirmatory) ChEMBL. No reference
Potency (binding) 25.1189 uM PubChem BioAssay. qHTS Assay for Inhibitors of MBNL1-poly(CUG) RNA binding. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) 30.1313 uM PUBCHEM_BIOASSAY: qHTS Assay to Find Inhibitors of T. brucei phosphofructokinase. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID488768, AID492961] ChEMBL. No reference
Potency (functional) = 31.6228 um PUBCHEM_BIOASSAY: qHTS Assay for Inhibitors Targeting the Menin-MLL Interaction in MLL Related Leukemias: Competition With Texas Red Labeled MLL-derived Mutant Peptide. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) 89.1251 uM PUBCHEM_BIOASSAY: qHTS for Inhibitors of Polymerase Iota. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID588623] ChEMBL. No reference

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

Bibliographic References

No literature references available for this target.

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