Detailed information for compound 1366299

Basic information

Technical information
  • TDR Targets ID: 1366299
  • Name: N-[(3-ethoxyphenyl)methyl]-1-azabicyclo[2.2.2 ]octan-8-amine hydrochloride
  • MW: 296.836 | Formula: C16H25ClN2O
  • H donors: 1 H acceptors: 0 LogP: 3.05 Rotable bonds: 5
    Rule of 5 violations (Lipinski): 1
  • SMILES: CCOc1cccc(c1)CNC1CN2CCC1CC2.Cl
  • InChi: 1S/C16H24N2O.ClH/c1-2-19-15-5-3-4-13(10-15)11-17-16-12-18-8-6-14(16)7-9-18;/h3-5,10,14,16-17H,2,6-9,11-12H2,1H3;1H
  • InChiKey: BUGGFAYGWRGXDH-UHFFFAOYSA-N  


Substructure search Similarity search

Network

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Synonyms

  • N-[(3-ethoxyphenyl)methyl]quinuclidin-3-amine hydrochloride
  • N-[(3-ethoxyphenyl)methyl]-3-quinuclidinamine hydrochloride
  • (3-ethoxybenzyl)-quinuclidin-3-yl-amine hydrochloride
  • MLS000538344
  • N-(3-ethoxybenzyl)quinuclidin-3-amine dihydrochloride
  • SMR000144381

Targets

Known targets for this compound

Species Target name Source Bibliographic reference
Homo sapiens SMAD family member 2 Starlite/ChEMBL No references
Homo sapiens GNAS complex locus Starlite/ChEMBL No references
Homo sapiens nuclear factor, erythroid 2-like 2 Starlite/ChEMBL No references

Predicted pathogen targets for this compound

By orthology
Species Potential target Known druggable target/s Ortholog Group
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) Get druggable targets OG5_131088 All targets in OG5_131088
Echinococcus granulosus guanine nucleotide binding protein Gs subunit Get druggable targets OG5_131088 All targets in OG5_131088
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) Get druggable targets OG5_131088 All targets in OG5_131088
Loa Loa (eye worm) MH2 domain-containing protein Get druggable targets OG5_131716 All targets in OG5_131716
Echinococcus granulosus guanine nucleotide binding protein Gs subunit Get druggable targets OG5_131088 All targets in OG5_131088
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) Get druggable targets OG5_131088 All targets in OG5_131088
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain Get druggable targets OG5_131088 All targets in OG5_131088
Loa Loa (eye worm) transcription factor SMAD2 Get druggable targets OG5_131716 All targets in OG5_131716
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit Get druggable targets OG5_131088 All targets in OG5_131088
Brugia malayi MH2 domain containing protein Get druggable targets OG5_131716 All targets in OG5_131716
Schistosoma japonicum ko:K04632 guanine nucleotide binding protein (G protein), alpha stimulating, putative Get druggable targets OG5_131088 All targets in OG5_131088
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit Get druggable targets OG5_131088 All targets in OG5_131088
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative Get druggable targets OG5_131088 All targets in OG5_131088
By sequence similarity to non orthologous known druggable targets
Species Potential target Known druggable target Length Alignment span Identity
Schistosoma mansoni GTP-binding protein alpha subunit gna GNAS complex locus 394 aa 450 aa 28.7 %
Brugia malayi MH2 domain containing protein SMAD family member 2 467 aa 405 aa 31.6 %
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Schistosoma mansoni terminal deoxycytidyl transferase 0.0038 0.004 0.0123
Trypanosoma cruzi DNA polymerase kappa, putative 0.0038 0.004 0.0123
Loa Loa (eye worm) RecQ helicase 0.0042 0.0047 0.0146
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.1876 0.3216 1
Loa Loa (eye worm) hypothetical protein 0.0053 0.0065 0.0202
Loa Loa (eye worm) hypothetical protein 0.0026 0.0019 0.006
Loa Loa (eye worm) hypothetical protein 0.0095 0.0137 0.0427
Toxoplasma gondii calcium binding egf domain-containing protein 0.0026 0.0019 0.0097
Brugia malayi hypothetical protein 0.0053 0.0065 0.0202
Plasmodium vivax aspartyl protease, putative 0.0145 0.0225 0.113
Leishmania major hypothetical protein, conserved 0.0045 0.0052 0.0243
Loa Loa (eye worm) hypothetical protein 0.0095 0.0137 0.0427
Loa Loa (eye worm) hypothetical protein 0.0026 0.0019 0.0058
Trichomonas vaginalis Crustacean calcium-binding protein, putative 0.0045 0.0052 0.0253
Schistosoma mansoni retinoic acid receptor RXR 0.0021 0.001 0.003
Loa Loa (eye worm) TYRA-2 protein 0.0095 0.0137 0.0427
Trichomonas vaginalis phosphofructokinase, putative 0.0108 0.0161 0.0805
Echinococcus granulosus family C2 unassigned peptidase C02 family 0.1007 0.1714 0.1714
Loa Loa (eye worm) beta-lactamase 0.0072 0.0099 0.0309
Giardia lamblia Cathepsin B precursor 0.0255 0.0414 0.3221
Mycobacterium tuberculosis Putative ferredoxin reductase 0.0108 0.016 0.2049
Schistosoma mansoni 6-phosphofructokinase 0.0108 0.0161 0.0501
Echinococcus multilocularis EF HAND 1, calcium binding site 0.0045 0.0052 0.0052
Giardia lamblia Hypothetical protein 0.0255 0.0414 0.3221
Onchocerca volvulus 0.1158 0.1975 1
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0188 0.0298 0.0927
Trichomonas vaginalis ap endonuclease, putative 0.0038 0.0039 0.0186
Loa Loa (eye worm) hypothetical protein 0.0072 0.0099 0.0309
Echinococcus granulosus calpain A 0.0489 0.0819 0.0819
Entamoeba histolytica cysteine protease, putative 0.0255 0.0414 0.2095
Trichomonas vaginalis conserved hypothetical protein 0.0038 0.0039 0.0188
Trichomonas vaginalis conserved hypothetical protein 0.0103 0.0152 0.0757
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0021 0.001 0.001
Schistosoma mansoni neuropeptide F-like receptor 0.0095 0.0137 0.0427
Schistosoma mansoni centrin-related 0.0045 0.0052 0.0162
Onchocerca volvulus 0.0145 0.0225 0.1141
Echinococcus multilocularis g protein coupled receptor 0.0095 0.0137 0.0137
Toxoplasma gondii calpain family cysteine protease domain-containing protein 0.0251 0.0407 0.2062
Echinococcus granulosus thyrotropin releasing hormone receptor 0.0095 0.0137 0.0137
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0621 0.1047 0.5085
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0621 0.1047 0.5085
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0145 0.0225 0.07
Schistosoma mansoni amine GPCR 0.0095 0.0137 0.0427
Brugia malayi beta-lactamase family protein 0.0072 0.0099 0.0309
Trichomonas vaginalis penicillin-binding protein, putative 0.0072 0.0099 0.0491
Schistosoma mansoni hypothetical protein 0.0095 0.0137 0.0427
Trypanosoma brucei DNA polymerase kappa, putative 0.0038 0.004 0.0182
Brugia malayi Trypsin family protein 0.0066 0.0089 0.0276
Echinococcus multilocularis calpain 5 0.0489 0.0819 0.0819
Loa Loa (eye worm) latrophilin receptor protein 2 0.0017 0.0003 0.0008
Schistosoma mansoni cercarial elastase (S01 family) 0.0066 0.0089 0.0276
Echinococcus granulosus Glutaredoxin protein 5 0.002 0.0008 0.0008
Schistosoma mansoni neuropeptide F-like receptor 0.0095 0.0137 0.0427
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0255 0.0414 0.1287
Plasmodium falciparum cysteine proteinase falcipain 2b 0.1158 0.1975 1
Echinococcus granulosus subfamily S1A unassigned peptidase S01 family 0.0066 0.0089 0.0089
Schistosoma mansoni cercarial elastase (S01 family) 0.0066 0.0089 0.0276
Onchocerca volvulus 0.0066 0.0089 0.045
Schistosoma mansoni neuropeptide receptor 0.0095 0.0137 0.0427
Entamoeba histolytica exodeoxyribonuclease III, putative 0.0038 0.0039 0.0197
Onchocerca volvulus 0.0042 0.0047 0.0237
Echinococcus multilocularis transmembrane protease serine 3 0.0066 0.0089 0.0089
Trypanosoma cruzi cruzipain precursor, putative 0.0366 0.0607 0.1887
Echinococcus multilocularis 7TM GPCR, rhodopsin 0.0095 0.0137 0.0137
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.06 0.1011 0.3143
Entamoeba histolytica protein kinase, putative 0.0032 0.003 0.0149
Trypanosoma brucei calpain-like cysteine peptidase, putative 0.075 0.1271 0.6174
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.0021 0.001 0.001
Loa Loa (eye worm) hypothetical protein 0.0095 0.0137 0.0427
Entamoeba histolytica PH domain containing protein kinase, putative 0.0022 0.0012 0.006
Loa Loa (eye worm) hypothetical protein 0.0095 0.0137 0.0427
Leishmania major cytochrome p450-like protein 0.0033 0.0031 0.0138
Entamoeba histolytica phosphofructokinase, putative 0.0108 0.0161 0.0815
Brugia malayi Nuclear hormone receptor family member nhr-41 0.0021 0.001 0.0031
Echinococcus multilocularis ATP dependent DNA helicase Q5 0.003 0.0025 0.0025
Trichomonas vaginalis calpain, putative 0.0251 0.0407 0.2053
Schistosoma mansoni hypothetical protein 0.0017 0.0003 0.0008
Brugia malayi Melatonin receptor type 1A 0.0095 0.0137 0.0427
Leishmania major calcineurin B subunit, putative 0.0045 0.0052 0.0243
Echinococcus granulosus rhodopsin orphan GPCR 0.0095 0.0137 0.0137
Trypanosoma cruzi major cysteine proteinase, putative 0.0302 0.0495 0.154
Plasmodium falciparum plasmepsin III 0.0145 0.0225 0.113
Plasmodium falciparum plasmepsin X 0.0145 0.0225 0.113
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.0021 0.001 0.001
Trypanosoma cruzi DNA polymerase kappa, putative 0.0038 0.004 0.0123
Brugia malayi PAN domain containing protein 0.0042 0.0047 0.0145
Echinococcus granulosus G protein coupled receptor 139 0.0095 0.0137 0.0137
Onchocerca volvulus 0.0792 0.1342 0.6796
Echinococcus granulosus nervana 2 0.002 0.0008 0.0008
Brugia malayi Nuclear hormone receptor family member nhr-40 0.0021 0.001 0.0031
Mycobacterium ulcerans cytochrome P450 185A4 Cyp185A4 0.0033 0.0031 0.1786
Brugia malayi 6-phosphofructokinase 0.0108 0.0161 0.0501
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.1205 0.2057 1
Mycobacterium leprae PROBABLE NADH DEHYDROGENASE NDH 0.0108 0.016 0.8689
Trypanosoma cruzi Domain of unknown function (DUF1935), putative 0.0206 0.033 0.1026
Echinococcus multilocularis g protein coupled receptor 0.0095 0.0137 0.0137
Entamoeba histolytica grainin 2 0.0053 0.0066 0.0335
Echinococcus granulosus fmrfamide receptor 0.0095 0.0137 0.0137
Trypanosoma cruzi prefoldin subunit, putative 0.0103 0.0152 0.0471
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0325 0.0536 0.1666
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0255 0.0414 0.2087
Echinococcus multilocularis sodium:potassium dependent atpase beta subunit 0.002 0.0008 0.0008
Loa Loa (eye worm) hypothetical protein 0.0095 0.0137 0.0427
Trypanosoma cruzi unspecified product 0.0355 0.0588 0.1829
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0792 0.1342 0.6792
Onchocerca volvulus 0.0072 0.0099 0.0503
Onchocerca volvulus 0.0095 0.0137 0.0696
Schistosoma mansoni cathepsin D (A01 family) 0.1675 0.2867 0.8916
Onchocerca volvulus Neurogenic locus notch homolog 0.0015 0 0.0001
Plasmodium vivax centrin-1, putative 0.0045 0.0052 0.0253
Brugia malayi PAN domain containing protein 0.0042 0.0047 0.0145
Mycobacterium tuberculosis Probable reductase 0.0108 0.016 0.2049
Leishmania major hypothetical protein, conserved 0.0134 0.0206 0.099
Toxoplasma gondii calmodulin CAM1 0.0046 0.0054 0.0272
Schistosoma mansoni opsin-like receptor 0.0095 0.0137 0.0427
Echinococcus granulosus voltage gated sodium channel Nav1 alpha subunit 0.0041 0.0044 0.0044
Trypanosoma brucei antigen, putative 0.0489 0.0819 0.3977
Plasmodium falciparum serine repeat antigen 2 0.0255 0.0414 0.2087
Echinococcus multilocularis rhodopsin orphan GPCR 0.0095 0.0137 0.0137
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0692 0.1171 0.5687
Echinococcus granulosus Tolloid protein 1 0.0026 0.0019 0.0019
Loa Loa (eye worm) G-protein-linked acetylcholine receptor protein 2 0.0095 0.0137 0.0427
Loa Loa (eye worm) hypothetical protein 0.0255 0.0414 0.1287
Brugia malayi Heterochromatin protein 1 0.0067 0.0091 0.0282
Brugia malayi Latrophilin receptor protein 2 0.0017 0.0003 0.0008
Loa Loa (eye worm) hypothetical protein 0.0095 0.0137 0.0427
Trypanosoma brucei protein I/6 0.0045 0.0052 0.0243
Loa Loa (eye worm) melatonin receptor type 1A 0.0095 0.0137 0.0427
Plasmodium falciparum prefoldin subunit 6, putative 0.0103 0.0152 0.0757
Trichomonas vaginalis Clan CA, family C1, cathepsin L or H-like cysteine peptidase 0.0255 0.0414 0.2087
Echinococcus multilocularis laminin 0.0026 0.0019 0.0019
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0095 0.0137 0.0427
Loa Loa (eye worm) aspartic protease BmAsp-1 0.0145 0.0225 0.0701
Trypanosoma brucei centrin, putative 0.0045 0.0052 0.0243
Echinococcus granulosus g-protein coupled receptor 0.0095 0.0137 0.0137
Schistosoma mansoni biogenic amine (5HT) receptor 0.0095 0.0137 0.0427
Trypanosoma brucei Calpain-like protein 1.2 0.06 0.1011 0.491
Plasmodium falciparum ataxin-2 like protein, putative 0.0053 0.0065 0.0317
Trichomonas vaginalis calcium binding proteins, putative 0.0045 0.0052 0.0253
Trypanosoma brucei unspecified product 0.0026 0.0019 0.0083
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0188 0.0298 0.0927
Loa Loa (eye worm) hypothetical protein 0.0026 0.0019 0.006
Treponema pallidum diphosphate--fructose-6-phosphate 1-phosphotransferase 0.0108 0.0161 1
Brugia malayi PAN domain containing protein 0.0042 0.0047 0.0145
Trypanosoma brucei DNA polymerase IV, putative 0.0038 0.004 0.0182
Brugia malayi Pre-SET motif family protein 0.0061 0.0079 0.0246
Leishmania major hypothetical protein, unknown function 0.0251 0.0407 0.1972
Schistosoma mansoni aminopeptidase PILS (M01 family) 0.0066 0.0089 0.0276
Echinococcus multilocularis subfamily S1A unassigned peptidase (S01 family) 0.0066 0.0089 0.0089
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0058 0.0074 0.0074
Brugia malayi PAN domain containing protein 0.0042 0.0047 0.0145
Echinococcus granulosus rhodopsin orphan GPCR 0.0095 0.0137 0.0137
Brugia malayi hypothetical protein 0.0145 0.0225 0.0701
Mycobacterium tuberculosis Probable isocitrate dehydrogenase [NADP] Icd1 (oxalosuccinate decarboxylase) (IDH) (NADP+-specific ICDH) (IDP) 0.0017 0.0003 0.0005
Brugia malayi isocitrate dehydrogenase 0.0017 0.0003 0.0009
Loa Loa (eye worm) cytoplasmic intermediate filament protein 0.003 0.0025 0.0079
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0206 0.033 0.1026
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0017 0.0003 0.0003
Echinococcus granulosus tm gpcr rhodopsin 0.0095 0.0137 0.0137
Mycobacterium tuberculosis NADPH-dependent mycothiol reductase Mtr 0.0047 0.0056 0.0692
Trypanosoma brucei META domain/Domain of unknown function (DUF1935), putative 0.0206 0.033 0.1595
Loa Loa (eye worm) hypothetical protein 0.0052 0.0065 0.0201
Toxoplasma gondii ABC1 family protein 0.0072 0.0099 0.0502
Plasmodium vivax serine-repeat antigen 4 (SERA), putative 0.0255 0.0414 0.2087
Onchocerca volvulus 0.0259 0.0421 0.2131
Brugia malayi cathepsin L precursor 0.0255 0.0414 0.1287
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0457 0.0763 0.2374
Trypanosoma brucei META domain/Domain of unknown function (DUF1935), putative 0.0206 0.033 0.1595
Plasmodium vivax plasmepsin IV, putative 0.0615 0.1037 0.5243
Trypanosoma cruzi programmed cell death 6 protein-like, putative 0.0045 0.0052 0.0162
Plasmodium falciparum cysteine proteinase falcipain 2a 0.1158 0.1975 1
Onchocerca volvulus 0.0095 0.0137 0.0696
Brugia malayi ATP-dependent DNA helicase, RecQ family protein 0.003 0.0025 0.0079
Entamoeba histolytica cysteine protease, putative 0.0621 0.1047 0.53
Onchocerca volvulus 0.0145 0.0225 0.1141
Schistosoma mansoni centrin 0.0045 0.0052 0.0162
Loa Loa (eye worm) calpain 0.0489 0.0819 0.2548
Trichomonas vaginalis Clan AA, family A1, cathepsin D-like aspartic peptidase 0.0615 0.1037 0.5243
Echinococcus multilocularis isocitrate dehydrogenase 0.0017 0.0003 0.0003
Echinococcus multilocularis serotonin receptor 0.0095 0.0137 0.0137
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0678 0.1145 0.3559
Brugia malayi hypothetical protein 0.0095 0.0137 0.0427
Trichomonas vaginalis calmodulin, putative 0.0045 0.0052 0.0253
Schistosoma mansoni ef hand domain family member A2 0.0045 0.0052 0.0162
Schistosoma mansoni calpain-7 (C02 family) 0.0489 0.0819 0.2547
Echinococcus granulosus allatostatin A receptor 0.0095 0.0137 0.0137
Schistosoma mansoni Mername-AA248 (C02 family) 0.0489 0.0819 0.2547
Trichomonas vaginalis calpain, putative 0.0251 0.0407 0.2053
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.0072 0.0099 0.1256
Echinococcus granulosus cathepsin l1 0.0792 0.1342 0.1342
Loa Loa (eye worm) hypothetical protein 0.0072 0.0099 0.0309
Plasmodium falciparum ataxin-2 like protein, putative 0.0053 0.0065 0.0317
Plasmodium falciparum serine repeat antigen 1 0.0255 0.0414 0.2087
Echinococcus granulosus lamin 0.0056 0.007 0.007
Echinococcus multilocularis survival motor neuron protein 1 0.0236 0.0381 0.0381
Schistosoma mansoni peptide (allatostatin/somatostatin)-like receptor 0.0095 0.0137 0.0427
Echinococcus granulosus G protein coupled 5 hydroxytryptamine receptor 0.0095 0.0137 0.0137
Trypanosoma cruzi mitochondrial calcium uptake 1, putative 0.0045 0.0052 0.0162
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0095 0.0137 0.0427
Leishmania major cysteine peptidase C (CPC),CPC cysteine peptidase, Clan CA, family C1, Cathepsin B-like 0.0756 0.1281 0.6222
Trypanosoma brucei DNA polymerase eta, putative 0.0063 0.0084 0.0396
Schistosoma mansoni calmodulin related calcium binding protein 0.0045 0.0052 0.0162
Trypanosoma cruzi DNA polymerase eta, putative 0.0037 0.0038 0.0119
Loa Loa (eye worm) hypothetical protein 0.0021 0.001 0.0031
Trichomonas vaginalis conserved hypothetical protein 0.0255 0.0414 0.2087
Schistosoma mansoni hypothetical protein 0.0033 0.0031 0.0094
Schistosoma mansoni cathepsin C 0.0255 0.0414 0.1287
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0072 0.0099 0.0308
Onchocerca volvulus 0.1158 0.1975 1
Echinococcus granulosus neuropeptide FF receptor 2 0.0095 0.0137 0.0137
Schistosoma mansoni RAR-like nuclear receptor 0.0021 0.001 0.003
Schistosoma mansoni chromobox protein 0.0067 0.0091 0.0281
Echinococcus multilocularis rhodopsin orphan GPCR 0.0095 0.0137 0.0137
Loa Loa (eye worm) ATP-dependent DNA helicase 0.003 0.0025 0.0079
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.075 0.1271 0.3951
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0751 0.1272 0.6181
Leishmania major DNA polymerase kappa, putative 0.0038 0.004 0.0182
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0145 0.0225 0.07
Loa Loa (eye worm) hypothetical protein 0.0251 0.0407 0.1267
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0188 0.0298 0.0298
Trypanosoma brucei calpain, putative 0.0251 0.0407 0.1972
Loa Loa (eye worm) hypothetical protein 0.0095 0.0137 0.0427
Brugia malayi Cathepsin L-like precursor 0.1158 0.1975 0.6142
Loa Loa (eye worm) hypothetical protein 0.0095 0.0137 0.0427
Giardia lamblia Dipeptidyl-peptidase I precursor 0.0255 0.0414 0.3221
Brugia malayi Serotonin receptor 0.0095 0.0137 0.0427
Loa Loa (eye worm) hypothetical protein 0.0095 0.0137 0.0427
Brugia malayi Cathepsin L-like precursor 0.0792 0.1342 0.4174
Leishmania major small myristoylated protein-3, putative 0.0301 0.0494 0.2395
Brugia malayi calpain 5 0.0238 0.0386 0.12
Trypanosoma brucei unspecified product 0.0206 0.033 0.1595
Toxoplasma gondii aspartyl protease ASP1 0.0615 0.1037 0.5248
Trichomonas vaginalis phosphofructokinase, putative 0.0108 0.0161 0.0805
Echinococcus granulosus 7tm_1 domain containing protein 0.0095 0.0137 0.0137
Schistosoma mansoni peptidylglycine monooxygenase 0.0031 0.0027 0.0083
Echinococcus granulosus cathepsin L cysteine proteinase 0.1158 0.1975 0.1975
Trypanosoma brucei Domain of unknown function (DUF1935), putative 0.0206 0.033 0.1595
Giardia lamblia Cathepsin L precursor 0.0255 0.0414 0.3221
Onchocerca volvulus 0.0095 0.0137 0.0696
Giardia lamblia Cysteine protease 0.0255 0.0414 0.3221
Entamoeba histolytica cysteine protease, putative 0.0621 0.1047 0.53
Brugia malayi Pepsin A precursor 0.0145 0.0225 0.0701
Mycobacterium tuberculosis Probable lipase LipD 0.0072 0.0099 0.1256
Brugia malayi Nuclear hormone receptor family member nhr-14 0.0021 0.001 0.0031
Plasmodium falciparum centrin-1 0.0045 0.0052 0.0253
Entamoeba histolytica cysteine protease, putative 0.0621 0.1047 0.53
Mycobacterium ulcerans beta-lactamase 0.0072 0.0099 0.6099
Trichomonas vaginalis calcium binding protein, putative 0.0045 0.0052 0.0253
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0794 0.1347 0.6544
Brugia malayi Copper type II ascorbate-dependent monooxygenase, C-terminal domain containing protein 0.1169 0.1994 0.6202
Trypanosoma cruzi cysteine peptidase, putative 0.1205 0.2057 0.6395
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0145 0.0225 0.07
Onchocerca volvulus 0.0066 0.0089 0.045
Schistosoma mansoni survival motor neuron protein 0.0048 0.0057 0.0177
Brugia malayi Cytochrome P450 family protein 0.0033 0.0031 0.0096
Echinococcus multilocularis serine threonine protein kinase nrc serine threonine protein kinase gad 0.002 0.0009 0.0009
Brugia malayi Cathepsin L-like precursor 0.1158 0.1975 0.6142
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.056 0.0942 0.2929
Loa Loa (eye worm) TAR-binding protein 0.0067 0.0089 0.0277
Loa Loa (eye worm) hypothetical protein 0.0236 0.0381 0.1185
Trypanosoma brucei calpain-like protein, putative 0.075 0.1271 0.6174
Echinococcus granulosus cysteine protease 0.0621 0.1047 0.1047
Echinococcus granulosus ATP dependent DNA helicase Q1 0.003 0.0025 0.0025
Schistosoma mansoni cercarial elastase (S01 family) 0.0066 0.0089 0.0276
Trypanosoma brucei hypothetical protein 0.0512 0.0859 0.4168
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.1205 0.2057 1
Trypanosoma brucei Calpain-like protein CALP1.3 0.0457 0.0763 0.3705
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0756 0.1281 0.6479
Trypanosoma brucei DNA polymerase kappa, putative 0.0038 0.004 0.0182
Trypanosoma cruzi Domain of unknown function (DUF1935), putative 0.0206 0.033 0.1026
Schistosoma mansoni coup transcription factor 0.0021 0.001 0.003
Loa Loa (eye worm) hypothetical protein 0.0021 0.001 0.0031
Plasmodium vivax unspecified product 0.0621 0.1047 0.5295
Brugia malayi neuropeptide F receptor 0.0095 0.0137 0.0427
Mycobacterium tuberculosis Conserved protein 0.0072 0.0099 0.1256
Echinococcus multilocularis neuropeptide receptor 0.0095 0.0137 0.0137
Trypanosoma cruzi prefoldin subunit, putative 0.0103 0.0152 0.0471
Trypanosoma brucei rac serine-threonine kinase, putative 0.0032 0.003 0.0132
Brugia malayi cathepsin Z-like cysteine proteinase 0.0255 0.0414 0.1287
Brugia malayi Cathepsin L-like precursor 0.1158 0.1975 0.6142
Mycobacterium tuberculosis Probable peptidoglycan hydrolase 0.0028 0.0023 0.0262
Brugia malayi Papain family cysteine protease containing protein 0.0255 0.0414 0.1287
Plasmodium vivax aspartyl protease, putative 0.0145 0.0225 0.113
Trypanosoma brucei DNA polymerase kappa, putative 0.0026 0.0019 0.0083
Trypanosoma cruzi apurinic/apyrimidinic endonuclease 0.0038 0.0039 0.0121
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0145 0.0225 0.07
Onchocerca volvulus 0.0048 0.0057 0.0289
Onchocerca volvulus 0.003 0.0025 0.0128
Giardia lamblia Cathepsin L-like protease 0.0255 0.0414 0.3221
Schistosoma mansoni hypothetical protein 0.0095 0.0137 0.0427
Echinococcus granulosus laminin 0.0026 0.0019 0.0019
Echinococcus multilocularis ecdysone induced protein 78C 0.0021 0.001 0.001
Loa Loa (eye worm) hypothetical protein 0.0095 0.0137 0.0427
Toxoplasma gondii microneme protein MIC4 0.0042 0.0047 0.0236
Toxoplasma gondii EF hand domain-containing protein 0.0045 0.0052 0.0264
Plasmodium vivax unspecified product 0.0255 0.0414 0.2087
Loa Loa (eye worm) neuropeptide F receptor 0.0095 0.0137 0.0427
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0095 0.0137 0.0137
Echinococcus granulosus tissue type plasminogen activator 0.0134 0.0206 0.0206
Echinococcus multilocularis hypothetical protein 0.0489 0.0819 0.0819
Mycobacterium tuberculosis Probable NADH dehydrogenase Ndh 0.0108 0.016 0.2049
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0095 0.0137 0.0137
Trypanosoma cruzi cruzipain precursor, putative 0.1205 0.2057 0.6395
Loa Loa (eye worm) hypothetical protein 0.0072 0.0099 0.0309
Giardia lamblia Cathepsin B precursor 0.0255 0.0414 0.3221
Trichomonas vaginalis phosphofructokinase, putative 0.0029 0.0025 0.0113
Toxoplasma gondii microneme protein, putative 0.0042 0.0047 0.0236
Echinococcus granulosus neuropeptide s receptor 0.1055 0.1797 0.1797
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.1158 0.1975 1
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.1158 0.1975 1
Brugia malayi Hemopexin family protein 0.0033 0.0031 0.0095
Echinococcus multilocularis brain tumor protein 0.0031 0.0027 0.0027
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.0072 0.0099 0.1256
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0188 0.0298 0.0927
Mycobacterium ulcerans DNA polymerase IV 0.0038 0.004 0.235
Echinococcus multilocularis tissue type plasminogen activator 0.0134 0.0206 0.0206
Onchocerca volvulus Heterochromatin protein 1 homolog 0.0041 0.0044 0.0225
Loa Loa (eye worm) hypothetical protein 0.0026 0.0019 0.006
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0095 0.0137 0.0427
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0255 0.0414 0.2087
Trypanosoma cruzi calpain cysteine peptidase, putative 0.075 0.1271 0.3951
Schistosoma mansoni calmodulin 0.0045 0.0052 0.0162
Trypanosoma cruzi centrin-3 0.0053 0.0066 0.0206
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.1205 0.2057 1
Mycobacterium ulcerans lipase LipD 0.0072 0.0099 0.6099
Schistosoma mansoni cercarial elastase (S01 family) 0.0066 0.0089 0.0276
Trichomonas vaginalis Clan CA, family C1, cathepsin H-like cysteine peptidase 0.0255 0.0414 0.2087
Schistosoma mansoni calpain C (C02 family) 0.0489 0.0819 0.2547
Loa Loa (eye worm) hypothetical protein 0.0028 0.0023 0.007
Trichomonas vaginalis D-aminoacylase, putative 0.0072 0.0099 0.0491
Brugia malayi Tachykinin-like peptides receptor 99D 0.0095 0.0137 0.0427
Trypanosoma cruzi hypothetical protein, conserved 0.0206 0.033 0.1026
Trichomonas vaginalis phosphofructokinase, putative 0.0029 0.0025 0.0113
Brugia malayi B-box type zinc-finger protein ncl-1 0.0031 0.0027 0.0084
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0072 0.0098 0.0304
Giardia lamblia Cathepsin B precursor 0.0255 0.0414 0.3221
Toxoplasma gondii subtilisin SUB12 0.0042 0.0047 0.0236
Loa Loa (eye worm) hypothetical protein 0.0325 0.0536 0.1666
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.1158 0.1975 1
Onchocerca volvulus Matrilysin homolog 0.0023 0.0014 0.007
Toxoplasma gondii phosphofructokinase domain-containing protein 0.0029 0.0025 0.0124
Trypanosoma cruzi kinesin, putative 0.0238 0.0386 0.12
Schistosoma mansoni hypothetical protein 0.0017 0.0003 0.0008
Schistosoma mansoni mitochondrial solute carrier 0.0045 0.0052 0.0162
Plasmodium vivax serine-repeat antigen 2 (SERA) 0.0255 0.0414 0.2087
Brugia malayi sulfakinin receptor protein 0.0095 0.0137 0.0427
Trypanosoma brucei unspecified product 0.0038 0.004 0.0182
Trypanosoma cruzi centrin, putative 0.0053 0.0066 0.0206
Onchocerca volvulus Bile acid receptor homolog 0.0021 0.001 0.005
Schistosoma mansoni dipeptidyl-peptidase I (C01 family) 0.0255 0.0414 0.1287
Echinococcus multilocularis g protein coupled receptor 0.0095 0.0137 0.0137
Loa Loa (eye worm) calpain family protein 1 0.0723 0.1223 0.3804
Brugia malayi hypothetical protein 0.0095 0.0137 0.0427
Brugia malayi beta-lactamase family protein 0.0072 0.0099 0.0309
Onchocerca volvulus 0.0072 0.0099 0.0503
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.1158 0.1975 1
Onchocerca volvulus 0.0042 0.0047 0.0237
Schistosoma mansoni ap endonuclease 0.0038 0.0039 0.0121
Plasmodium falciparum AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0038 0.0039 0.0186
Echinococcus granulosus tar DNA binding protein 0.0067 0.0089 0.0089
Loa Loa (eye worm) hypothetical protein 0.0095 0.0137 0.0427
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0568 0.0956 0.2971
Echinococcus granulosus calpain 0.0489 0.0819 0.0819
Trypanosoma brucei variant surface glycoprotein (VSG), putative 0.0261 0.0425 0.2059
Trypanosoma brucei centrin, putative 0.0045 0.0052 0.0243
Schistosoma mansoni hypothetical protein 0.0045 0.0052 0.0162
Plasmodium vivax serine-repeat antigen 3 (SERA) 0.0255 0.0414 0.2087
Brugia malayi Unidentified vitellogenin-linked transcript protein 6, putative 0.0095 0.0137 0.0427
Loa Loa (eye worm) aspartyl protease 6 0.0145 0.0225 0.0701
Leishmania major cathepsin L-like protease 0.1205 0.2057 1
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0021 0.001 0.001
Entamoeba histolytica hypothetical protein, conserved 0.0046 0.0054 0.0272
Trypanosoma brucei mitochondrial calcium uptake 1 0.0045 0.0052 0.0243
Loa Loa (eye worm) hypothetical protein 0.0472 0.079 0.2457
Loa Loa (eye worm) Papain cysteine protease/cathepsin propeptide inhibitor-containing protein 0.1158 0.1975 0.6142
Entamoeba histolytica cysteine protease, putative 0.0621 0.1047 0.53
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0016 0.0002 0.0007
Trypanosoma brucei DNA polymerase kappa, putative 0.0038 0.004 0.0182
Trypanosoma brucei hypothetical protein, conserved 0.0334 0.0551 0.267
Loa Loa (eye worm) isocitrate dehydrogenase 0.0017 0.0003 0.0009
Loa Loa (eye worm) hypothetical protein 0.0021 0.001 0.0031
Loa Loa (eye worm) hypothetical protein 0.0095 0.0137 0.0427
Giardia lamblia Cathepsin B precursor 0.0756 0.1281 1
Loa Loa (eye worm) ctsf protein 0.1158 0.1975 0.6142
Brugia malayi ImpB/MucB/SamB family protein 0.0038 0.004 0.0123
Brugia malayi Cathepsin L-like precursor 0.1158 0.1975 0.6142
Echinococcus granulosus dihydrolipoamide dehydrogenase 0.0016 0.0002 0.0002
Toxoplasma gondii LsmAD domain-containing protein 0.0053 0.0065 0.0328
Brugia malayi Nuclear hormone receptor family member nhr-31 0.0021 0.001 0.0031
Trypanosoma cruzi cysteine proteinase, putative 0.0621 0.1047 0.3255
Echinococcus multilocularis muscleblind protein 1 0.0154 0.0241 0.0241
Plasmodium vivax hypothetical protein, conserved 0.0046 0.0054 0.0261
Echinococcus multilocularis fibrillin 1 0.0026 0.0019 0.0019
Trypanosoma brucei calpain-like protein, putative 0.0489 0.0819 0.3977
Echinococcus granulosus chromobox protein 1 0.0067 0.0091 0.0091
Echinococcus multilocularis neuronal calcium sensor 0.0045 0.0052 0.0052
Toxoplasma gondii microneme protein MIC17A 0.0042 0.0047 0.0236
Trichomonas vaginalis phosphofructokinase, putative 0.0108 0.0161 0.0805
Trypanosoma cruzi calpain cysteine peptidase, putative 0.0457 0.0763 0.2374
Echinococcus multilocularis programmed cell death protein 0.0053 0.0066 0.0066
Plasmodium vivax serine-repeat antigen (SERA), putative 0.0255 0.0414 0.2087
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0255 0.0414 0.2087
Loa Loa (eye worm) hypothetical protein 0.0095 0.0137 0.0427
Toxoplasma gondii pyruvate dehydrogenase complex subunit PDH-E3II 0.0016 0.0002 0.0011
Brugia malayi Matrixin family protein 0.0023 0.0014 0.0043
Trypanosoma brucei C-8 sterol isomerase, putative 0.0359 0.0594 0.288
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.1158 0.1975 1
Brugia malayi cathepsin L-like cysteine proteinase 0.0255 0.0414 0.1287
Echinococcus granulosus nervana 2 0.002 0.0008 0.0008
Trichomonas vaginalis Clan CA, family C2, calpain-like cysteine peptidase 0.0251 0.0407 0.2053
Trichomonas vaginalis DNA helicase recq1, putative 0.0042 0.0047 0.0226
Brugia malayi calpain D 0.0251 0.0407 0.1267
Trichomonas vaginalis calmodulin, putative 0.0046 0.0054 0.0261
Loa Loa (eye worm) multiple epidermal growth factor-like domains 6 0.0026 0.0019 0.006
Schistosoma mansoni neuropeptide receptor 0.0095 0.0137 0.0427
Echinococcus multilocularis orexin receptor type 2 0.0095 0.0137 0.0137
Schistosoma mansoni DNA helicase recq5 0.003 0.0025 0.0078
Brugia malayi latrophilin 2 splice variant baaae 0.0036 0.0036 0.0112
Entamoeba histolytica calcium binding family protein 0.0045 0.0052 0.0264
Brugia malayi follicle stimulating hormone receptor 0.0095 0.0137 0.0427
Plasmodium vivax aspartyl proteinase, putative 0.0615 0.1037 0.5243
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0145 0.0225 0.07
Brugia malayi PAN domain containing protein 0.0042 0.0047 0.0145
Loa Loa (eye worm) hypothetical protein 0.003 0.0025 0.0079
Toxoplasma gondii 1,3(4)-beta-glucanase 0.0042 0.0047 0.0236
Loa Loa (eye worm) CXXC zinc finger family protein 0.003 0.0025 0.0079
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0439 0.0733 0.2278
Onchocerca volvulus Cathepsin F homolog 0.1158 0.1975 1
Toxoplasma gondii cathepsin CPL 0.1158 0.1975 1
Giardia lamblia Hypothetical protein 0.0255 0.0414 0.3221
Leishmania major hypothetical protein, conserved 0.0206 0.033 0.1595
Trypanosoma brucei Small kinetoplastid calpain-related protein 1-4 0.0206 0.033 0.1595
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.1158 0.1975 1
Onchocerca volvulus 0.1158 0.1975 1
Trypanosoma cruzi DNA polymerase kappa, putative 0.0038 0.004 0.0123
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0066 0.0089 0.0276
Echinococcus granulosus thioredoxin glutathione reductase 0.0047 0.0056 0.0056
Brugia malayi Isocitrate dehydrogenase 0.0017 0.0003 0.0009
Trichomonas vaginalis AGC family protein kinase 0.0032 0.003 0.0138
Loa Loa (eye worm) hypothetical protein 0.0021 0.001 0.0031
Trypanosoma brucei DNA polymerase kappa, putative 0.0038 0.004 0.0182
Mycobacterium ulcerans hydrolase 0.0028 0.0023 0.1272
Brugia malayi Cathepsin L-like precursor 0.1158 0.1975 0.6142
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0568 0.0956 0.2971
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.1158 0.1975 1
Echinococcus granulosus dro:myosuppressin receptor 0.0095 0.0137 0.0137
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.1158 0.1975 1
Toxoplasma gondii PAN domain-containing protein 0.0042 0.0047 0.0236
Echinococcus granulosus biogenic amine 5HT receptor 0.0095 0.0137 0.0137
Trypanosoma brucei calpain-like cysteine peptidase, putative 0.0261 0.0425 0.2059
Loa Loa (eye worm) hypothetical protein 0.0366 0.0607 0.1888
Trichomonas vaginalis DNA polymerase eta, putative 0.0038 0.004 0.0189
Onchocerca volvulus 0.0042 0.0047 0.0237
Brugia malayi Dopamine receptor protein 1 0.0095 0.0137 0.0427
Brugia malayi hypothetical protein 0.0095 0.0137 0.0427
Leishmania major calmodulin, putative 0.0045 0.0052 0.0243
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0021 0.001 0.0031
Loa Loa (eye worm) hypothetical protein 0.0066 0.0089 0.0276
Loa Loa (eye worm) hypothetical protein 0.0792 0.1342 0.4174
Loa Loa (eye worm) hypothetical protein 0.0095 0.0137 0.0427
Loa Loa (eye worm) RNA recognition domain-containing protein domain-containing protein 0.0067 0.0089 0.0277
Loa Loa (eye worm) hypothetical protein 0.0042 0.0047 0.0145
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0794 0.1347 0.4187
Echinococcus multilocularis thyrotropin releasing hormone receptor 0.0095 0.0137 0.0137
Plasmodium vivax prefoldin subunit 6, putative 0.0103 0.0152 0.0757
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0145 0.0225 0.07
Brugia malayi phosphofructokinase 0.0108 0.0161 0.0501
Plasmodium vivax 6-phosphofructokinase, putative 0.0029 0.0025 0.0113
Loa Loa (eye worm) MH2 domain-containing protein 0.0144 0.0223 0.0694
Trypanosoma cruzi trypanothione reductase, putative 0.0047 0.0056 0.0173
Trypanosoma brucei centrin-3 0.0053 0.0066 0.0311
Loa Loa (eye worm) hypothetical protein 0.0255 0.0414 0.1287
Trichomonas vaginalis Clan CA, family C2, calpain-like cysteine peptidase 0.0251 0.0407 0.2053
Loa Loa (eye worm) RING finger protein nhl-1 0.0031 0.0027 0.0084
Entamoeba histolytica hypothetical protein 0.0031 0.0027 0.0135
Onchocerca volvulus Cathepsin L homolog 0.1158 0.1975 1
Loa Loa (eye worm) hypothetical protein 0.0095 0.0137 0.0427
Loa Loa (eye worm) hypothetical protein 0.0095 0.0137 0.0427
Echinococcus granulosus cathepsin l cysteine peptidase 0.1158 0.1975 0.1975
Schistosoma mansoni tar DNA-binding protein 0.0067 0.0089 0.0277
Giardia lamblia Haloacid dehalogenase-like hydrolase family 0.0031 0.0027 0.0192
Onchocerca volvulus 0.0042 0.0047 0.0237
Schistosoma mansoni rab 0.0045 0.0052 0.0162
Trypanosoma cruzi small myristoylated protein 1-2 0.0355 0.0588 0.1829
Leishmania major hypothetical protein, conserved 0.0206 0.033 0.1595
Brugia malayi 6-phosphofructokinase 0.0108 0.0161 0.0501
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0021 0.001 0.001
Echinococcus multilocularis neuropeptide receptor A26 0.1055 0.1797 0.1797
Leishmania major cathepsin L-like protease 0.1158 0.1975 0.9604
Schistosoma mansoni family C2 unassigned peptidase (C02 family) 0.1007 0.1714 0.5328
Brugia malayi Copper type II ascorbate-dependent monooxygenase, C-terminal domain containing protein 0.0306 0.0503 0.1563
Entamoeba histolytica cysteine protease, putative 0.0255 0.0414 0.2095
Brugia malayi Nuclear hormone receptor family member nhr-1 0.0021 0.001 0.0031
Echinococcus granulosus brain tumor protein 0.0031 0.0027 0.0027
Echinococcus granulosus retinoic acid receptor rxr beta a 0.0021 0.001 0.001
Loa Loa (eye worm) AGC/RSK/P70 protein kinase 0.003 0.0026 0.0081
Leishmania major small myristoylated protein-1 0.0355 0.0588 0.2852
Toxoplasma gondii PAN domain-containing protein 0.0042 0.0047 0.0236
Echinococcus multilocularis G protein coupled receptor 139 0.0095 0.0137 0.0137
Trichomonas vaginalis AGC family protein kinase 0.0032 0.003 0.0138
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0021 0.001 0.003
Brugia malayi hypothetical protein 0.0095 0.0137 0.0427
Loa Loa (eye worm) ImpB/MucB/SamB family protein 0.0038 0.004 0.0123
Entamoeba histolytica cysteine proteinase, putative 0.0621 0.1047 0.53
Trypanosoma brucei flagellum-adhesion glycoprotein, putative 0.0031 0.0027 0.0119
Schistosoma mansoni hypothetical protein 0.0048 0.0057 0.0177
Echinococcus multilocularis GPCR, family 2 0.0017 0.0003 0.0003
Onchocerca volvulus 0.0045 0.0052 0.0265
Loa Loa (eye worm) hypothetical protein 0.0134 0.0206 0.064
Loa Loa (eye worm) B-box zinc finger family protein 0.0031 0.0027 0.0084
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0439 0.0733 0.3555
Schistosoma mansoni cercarial elastase (S01 family) 0.0066 0.0089 0.0276
Giardia lamblia Sgs1 DNA helicase, putative 0.003 0.0025 0.0179
Plasmodium falciparum plasmepsin VIII, putative 0.0145 0.0225 0.113
Schistosoma mansoni biogenic amine (5HT) receptor 0.0095 0.0137 0.0427
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0095 0.0137 0.0427
Entamoeba histolytica cysteine protease, putative 0.0621 0.1047 0.53
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.1158 0.1975 1
Trichomonas vaginalis set domain proteins, putative 0.0477 0.0799 0.4037
Mycobacterium tuberculosis Possible DNA-damage-inducible protein P DinP (DNA polymerase V) (pol IV 2) (DNA nucleotidyltransferase (DNA-directed)) 0.0038 0.004 0.0484
Trypanosoma cruzi DNA polymerase eta, putative 0.0063 0.0084 0.026
Plasmodium vivax vivapain-2 0.1158 0.1975 1
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0017 0.0003 0.0003
Trichomonas vaginalis calpain, putative 0.0251 0.0407 0.2053
Loa Loa (eye worm) hypothetical protein 0.0038 0.0039 0.0123
Leishmania major DNA polymerase kappa, putative,DNA polymerase IV, putative 0.0038 0.004 0.0182
Leishmania major small myristoylated protein 4, putative 0.056 0.0942 0.4574
Echinococcus granulosus tm gpcr rhodopsin 0.0095 0.0137 0.0137
Loa Loa (eye worm) hypothetical protein 0.0031 0.0027 0.0084
Echinococcus multilocularis cysteine protease 0.1158 0.1975 0.1975
Loa Loa (eye worm) 5-hydroxytryptamine 2C receptor 0.0095 0.0137 0.0427
Brugia malayi KE2 family protein 0.0103 0.0152 0.0472
Loa Loa (eye worm) hypothetical protein 0.0095 0.0137 0.0427
Schistosoma mansoni hypothetical protein 0.0095 0.0137 0.0427
Schistosoma mansoni muscarinic acetylcholine (GAR) receptor 0.0095 0.0137 0.0427
Trypanosoma cruzi rac serine-threonine kinase, putative 0.0022 0.0012 0.0037
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.003 0.0025 0.0127
Treponema pallidum NADH oxidase 0.0016 0.0002 0.0137
Echinococcus multilocularis geminin 0.0348 0.0576 0.0576
Schistosoma mansoni cathepsin F (C01 family) 0.1158 0.1975 0.6142
Brugia malayi Cathepsin L-like cysteine proteinase 0.0792 0.1342 0.4174
Trypanosoma brucei Present in the outer mitochondrial membrane proteome 33 0.0045 0.0052 0.0243
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0017 0.0003 0.0003
Entamoeba histolytica calmodulin, putative 0.0045 0.0052 0.0264
Plasmodium vivax vivapain-1 0.0621 0.1047 0.5295
Echinococcus multilocularis cathepsin L 0.0255 0.0414 0.0414
Echinococcus multilocularis growth hormone secretagogue receptor type 1 0.0095 0.0137 0.0137
Echinococcus multilocularis dihydrolipoamide dehydrogenase 0.0016 0.0002 0.0002
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.0621 0.1047 0.3255
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0066 0.0089 0.0276
Trypanosoma brucei glucosamine 6-phosphate n-acetyltransferase 0.0251 0.0407 0.1972
Loa Loa (eye worm) TK/ROR protein kinase 0.0134 0.0206 0.064
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0255 0.0414 0.2087
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0489 0.0819 0.2547
Leishmania major centrin, putative 0.0045 0.0052 0.0243
Loa Loa (eye worm) hypothetical protein 0.0095 0.0137 0.0427
Leishmania major DNA polymerase eta, putative 0.0063 0.0084 0.0396
Trypanosoma brucei DNA polymerase kappa, putative 0.0038 0.004 0.0182
Brugia malayi Protein kinase domain containing protein 0.0134 0.0206 0.064
Plasmodium falciparum ATP-dependent 6-phosphofructokinase 0.0029 0.0025 0.0113
Onchocerca volvulus Matrilysin homolog 0.0051 0.0062 0.0316
Schistosoma mansoni neuronal calcium sensor 0.0045 0.0052 0.0162
Trypanosoma brucei cytoskeleton-associated protein CAP5.5, putative 0.0457 0.0763 0.3705
Trypanosoma brucei Component of motile flagella 41 0.0045 0.0052 0.0243
Mycobacterium tuberculosis Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB 0.0108 0.016 0.2049
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0255 0.0414 0.2087
Loa Loa (eye worm) hypothetical protein 0.0021 0.001 0.0031
Trichomonas vaginalis calmodulin, putative 0.0045 0.0052 0.0253
Loa Loa (eye worm) bone morphogenetic protein 1b 0.0026 0.0019 0.006
Trichomonas vaginalis Clan CA, family C2, calpain-like cysteine peptidase 0.0251 0.0407 0.2053
Echinococcus granulosus orexin receptor type 2 0.0095 0.0137 0.0137
Mycobacterium tuberculosis Possible penicillin-binding protein 0.0463 0.0774 1
Giardia lamblia Cathepsin L precursor 0.0255 0.0414 0.3221
Echinococcus multilocularis musashi 0.0056 0.007 0.007
Trypanosoma brucei cysteine peptidase, putative 0.0457 0.0763 0.3705
Schistosoma mansoni microtubule-associated protein tau 0.0726 0.1228 0.3819
Loa Loa (eye worm) intermediate filament protein 0.0056 0.007 0.0218
Loa Loa (eye worm) hypothetical protein 0.0023 0.0014 0.0043
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0065 0.0087 0.027
Loa Loa (eye worm) hypothetical protein 0.0015 0 0.0001
Loa Loa (eye worm) hypothetical protein 0.0962 0.1635 0.5085
Brugia malayi G-protein coupled receptor 0.0095 0.0137 0.0427
Trichomonas vaginalis phosphofructokinase, putative 0.0108 0.0161 0.0805
Trichomonas vaginalis calmodulin, putative 0.0045 0.0052 0.0253
Echinococcus granulosus growth hormone secretagogue receptor type 1 0.0095 0.0137 0.0137
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0145 0.0225 0.07
Loa Loa (eye worm) hypothetical protein 0.0063 0.0084 0.026
Schistosoma mansoni chromobox protein 0.0067 0.0091 0.0281
Echinococcus granulosus prefoldin subunit 6 0.0103 0.0152 0.0152
Echinococcus multilocularis Peptidase S1 S6, chymotrypsin Hap 0.0066 0.0089 0.0089
Trypanosoma cruzi isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0017 0.0003 0.0008
Loa Loa (eye worm) hypothetical protein 0.0095 0.0137 0.0427
Trypanosoma brucei DNA polymerase kappa, putative 0.0026 0.0019 0.0083
Brugia malayi Calcitonin receptor-like protein seb-1 0.0052 0.0065 0.0201
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0489 0.0819 0.2547
Loa Loa (eye worm) hypothetical protein 0.1876 0.3216 1
Echinococcus granulosus histone lysine methyltransferase setb 0.0061 0.0079 0.0079
Leishmania major cathepsin L-like protease 0.1205 0.2057 1
Loa Loa (eye worm) AGC/AKT protein kinase 0.0032 0.003 0.0092
Trypanosoma brucei META domain/Domain of unknown function (DUF1935), putative 0.0206 0.033 0.1595
Leishmania major hypothetical protein, conserved 0.0046 0.0054 0.0251
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0021 0.001 0.0031
Entamoeba histolytica hypothetical protein 0.0043 0.0049 0.0248
Trypanosoma brucei cytochrome P450, putative 0.0033 0.0031 0.0138
Loa Loa (eye worm) EF hand family protein 0.0045 0.0052 0.0163
Trypanosoma brucei DNA polymerase kappa, putative 0.0038 0.004 0.0182
Brugia malayi hypothetical protein 0.016 0.025 0.0778
Trichomonas vaginalis Clan CA, family C1, cathepsin L, S or H-like cysteine peptidase 0.0255 0.0414 0.2087
Trypanosoma cruzi conserved protein 0.0466 0.0779 0.2421
Loa Loa (eye worm) hypothetical protein 0.0095 0.0137 0.0427
Brugia malayi fibroinase precursor 0.0255 0.0414 0.1287
Schistosoma mansoni biogenic amine (octopamine/dopamine) receptor 0.0095 0.0137 0.0427
Brugia malayi Copper type II ascorbate-dependent monooxygenase, C-terminal domain containing protein 0.0621 0.1047 0.3256
Brugia malayi cathepsin Z-like cysteine proteinase 0.0255 0.0414 0.1287
Leishmania major prefoldin subunit, putative 0.0103 0.0152 0.0727
Plasmodium vivax aspartyl protease, putative 0.0145 0.0225 0.113
Brugia malayi PAN domain containing protein 0.0042 0.0047 0.0145
Loa Loa (eye worm) hypothetical protein 0.0095 0.0137 0.0427
Echinococcus multilocularis neuropeptide s receptor 0.1055 0.1797 0.1797
Trichomonas vaginalis ap endonuclease, putative 0.0038 0.0039 0.0186
Schistosoma mansoni calcium binding atopy-related autoantigen 0.0046 0.0054 0.0167
Loa Loa (eye worm) hypothetical protein 0.0095 0.0137 0.0427
Echinococcus multilocularis rhodopsin orphan GPCR 0.0095 0.0137 0.0137
Leishmania major calpain family cysteine protease-like protein 0.0457 0.0763 0.3705
Echinococcus granulosus g protein coupled receptor 0.0095 0.0137 0.0137
Schistosoma mansoni hypothetical protein 0.0095 0.0137 0.0427
Giardia lamblia Encystation-specific protease 0.0255 0.0414 0.3221
Brugia malayi cahepsin L-like non-peptiedase homolog 0.0255 0.0414 0.1287
Giardia lamblia Cathepsin L precursor 0.0255 0.0414 0.3221
Trichomonas vaginalis D-aminoacylase, putative 0.0072 0.0099 0.0491
Echinococcus multilocularis rhodopsin orphan GPCR 0.0095 0.0137 0.0137
Plasmodium falciparum RAC-beta serine/threonine protein kinase 0.002 0.0009 0.0032
Loa Loa (eye worm) hypothetical protein 0.0792 0.1342 0.4174
Trichomonas vaginalis phosphofructokinase, putative 0.0029 0.0025 0.0113
Trichomonas vaginalis calcium binding protein, putative 0.0053 0.0066 0.0324
Brugia malayi Papain family cysteine protease containing protein 0.1158 0.1975 0.6142
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0061 0.0079 0.0245
Trypanosoma cruzi hypothetical protein, conserved 0.0206 0.033 0.1026
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0145 0.0225 0.07
Onchocerca volvulus 0.0056 0.007 0.0354
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0794 0.1347 0.4187
Trypanosoma brucei DNA polymerase kappa, putative 0.0026 0.0019 0.0083
Brugia malayi Muscleblind-like protein 0.0154 0.0241 0.0749
Toxoplasma gondii isocitrate dehydrogenase 0.0017 0.0003 0.0013
Loa Loa (eye worm) hypothetical protein 0.0023 0.0014 0.0043
Mycobacterium tuberculosis Probable 6-phosphofructokinase PfkA (phosphohexokinase) (phosphofructokinase) 0.0108 0.0161 0.2059
Echinococcus multilocularis calmodulin 0.0045 0.0052 0.0052
Trichomonas vaginalis calcium binding protein, putative 0.0045 0.0052 0.0253
Leishmania major receptor-type adenylate cyclase a-like protein 0.0206 0.033 0.1595
Trypanosoma cruzi cysteine peptidase, clan CA, family C1, cathepsin L-like, putative 0.0839 0.1424 0.4427
Plasmodium vivax rac-beta serine/threonine protein kinase, putative 0.002 0.0009 0.0032
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.1158 0.1975 1
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0095 0.0137 0.0137
Echinococcus multilocularis cathepsin b 0.1876 0.3216 0.3216
Loa Loa (eye worm) hypothetical protein 0.0711 0.1202 0.3738
Trypanosoma brucei calpain-like cysteine peptidase, putative 0.0512 0.0859 0.4168
Echinococcus granulosus terminal deoxycytidyl transferase rev1 0.0038 0.004 0.004
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.0072 0.0099 0.6099
Onchocerca volvulus 0.0066 0.0089 0.045
Trypanosoma cruzi cytoskeleton-associated protein CAP5.5, putative 0.0457 0.0763 0.2374
Entamoeba histolytica cysteine protease, putative 0.0621 0.1047 0.53
Echinococcus multilocularis calbindin 32 0.0046 0.0054 0.0054
Leishmania major hypothetical protein, conserved 0.0334 0.0551 0.267
Loa Loa (eye worm) hypothetical protein 0.0066 0.0089 0.0276
Trichomonas vaginalis conserved hypothetical protein 0.0038 0.0039 0.0188
Giardia lamblia Cathepsin L precursor 0.0255 0.0414 0.3221
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0751 0.1272 0.6181
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.1158 0.1975 1
Brugia malayi neuropeptide F receptor 0.0095 0.0137 0.0427
Mycobacterium leprae PROBABLE 6-PHOSPHOFRUCTOKINASE PFKA (PHOSPHOHEXOKINASE) (PHOSPHOFRUCTOKINASE) 0.0108 0.0161 0.8737
Leishmania major protein kinase, putative 0.0046 0.0053 0.0245
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0016 0.0002 0.0007
Brugia malayi CXXC zinc finger family protein 0.003 0.0025 0.0079
Mycobacterium tuberculosis Probable oxidoreductase 0.012 0.0181 0.2318
Mycobacterium tuberculosis PE-PGRS family protein PE_PGRS18 0.0031 0.0027 0.0317
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0072 0.0099 0.0309
Entamoeba histolytica phosphofructokinase, putative 0.0108 0.0161 0.0815
Schistosoma mansoni thyroid hormone receptor 0.0147 0.0227 0.0707
Echinococcus granulosus calpain 7 C02 family 0.0489 0.0819 0.0819
Echinococcus granulosus somatostatin receptor 0.0095 0.0137 0.0137
Trypanosoma brucei DNA polymerase kappa, putative 0.0038 0.004 0.0182
Echinococcus multilocularis neuropeptide receptor 0.0095 0.0137 0.0137
Echinococcus granulosus glycoprotein Antigen 5 0.0066 0.0089 0.0089
Echinococcus multilocularis programmed cell death protein 0.0053 0.0066 0.0066
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0255 0.0414 0.2087
Brugia malayi Eukaryotic aspartyl protease family protein 0.0145 0.0225 0.0701
Wolbachia endosymbiont of Brugia malayi exonuclease III 0.0038 0.0039 1
Entamoeba histolytica PH domain containing protein kinase, putative 0.0022 0.0012 0.006
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.0038 0.0039 0.0039
Loa Loa (eye worm) calmodulin-like protein 0.0045 0.0052 0.0163
Brugia malayi Cathepsin L-like precursor 0.1158 0.1975 0.6142
Echinococcus granulosus ATP dependent DNA helicase Q5 0.003 0.0025 0.0025
Echinococcus granulosus neuropeptide receptor A26 0.1055 0.1797 0.1797
Leishmania major calpain-like protein, putative,cysteine peptidase, Clan CA, family C2, putative 0.0457 0.0763 0.3705
Toxoplasma gondii exonuclease III APE 0.0038 0.0039 0.0197
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.042 0.0699 0.2173
Loa Loa (eye worm) hypothetical protein 0.0145 0.0225 0.0701
Loa Loa (eye worm) phosphofructokinase 0.0108 0.0161 0.0501
Loa Loa (eye worm) hypothetical protein 0.0018 0.0005 0.0016
Echinococcus granulosus lamin dm0 0.0056 0.007 0.007
Schistosoma mansoni peptide (FMRFamide/neurokinin-3)-like receptor 0.0095 0.0137 0.0427
Echinococcus granulosus calcium uptake protein 1 0.0046 0.0054 0.0054
Mycobacterium ulcerans 6-phosphofructokinase 0.0108 0.0161 1
Schistosoma mansoni memapsin-2 (A01 family) 0.0145 0.0225 0.07
Plasmodium falciparum plasmepsin II 0.0615 0.1037 0.5243
Echinococcus granulosus calmodulin 0.0045 0.0052 0.0052
Schistosoma mansoni tar DNA-binding protein 0.0067 0.0089 0.0277
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0095 0.0137 0.0427
Brugia malayi GnHR receptor homolog 0.0095 0.0137 0.0427
Echinococcus granulosus calpain 5 0.0489 0.0819 0.0819
Schistosoma mansoni neuropeptide f receptor 76f 0.0095 0.0137 0.0427
Loa Loa (eye worm) hypothetical protein 0.0036 0.0036 0.0112
Plasmodium falciparum serine repeat antigen 3 0.0255 0.0414 0.2087
Schistosoma mansoni hypothetical protein 0.0066 0.0089 0.0276
Trichomonas vaginalis esterase, putative 0.0072 0.0099 0.0491
Schistosoma mansoni cathepsin B (C01 family) 0.0255 0.0414 0.1287
Onchocerca volvulus 0.0095 0.0137 0.0696
Brugia malayi RE15519p 0.0095 0.0137 0.0427
Trypanosoma cruzi major cysteine proteinase, putative 0.0255 0.0414 0.1287
Loa Loa (eye worm) aspartic protease BmAsp-2 0.0615 0.1037 0.3224
Plasmodium vivax dipeptidyl aminopeptidase 2, putative 0.0255 0.0414 0.2087
Schistosoma mansoni hypothetical protein 0.0251 0.0407 0.1266
Trypanosoma cruzi calmodulin, putative 0.0045 0.0052 0.0162
Schistosoma mansoni cercarial elastase (S01 family) 0.0066 0.0089 0.0276
Trichomonas vaginalis Clan CA, family C1, cathepsin F-like cysteine peptidase 0.0255 0.0414 0.2087
Schistosoma mansoni calpain (C02 family) 0.0489 0.0819 0.2547
Leishmania major calmodulin, putative 0.0045 0.0052 0.0243
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0095 0.0137 0.0427
Trypanosoma cruzi isocitrate dehydrogenase, putative 0.0017 0.0003 0.0008
Leishmania major hypothetical protein, conserved 0.0466 0.0779 0.3779
Schistosoma mansoni calpain-7 (C02 family) 0.0489 0.0819 0.2547
Entamoeba histolytica hypothetical protein 0.0043 0.0049 0.0248
Echinococcus granulosus cathepsin L 0.0621 0.1047 0.1047
Loa Loa (eye worm) hypothetical protein 0.0366 0.0607 0.1888
Schistosoma mansoni myosin xvIII 0.0095 0.0137 0.0427
Schistosoma mansoni SmCB2 peptidase (C01 family) 0.1876 0.3216 1
Onchocerca volvulus 0.0325 0.0536 0.2713
Toxoplasma gondii PAN/Apple domain-containing protein 0.0042 0.0047 0.0236
Plasmodium falciparum serine repeat antigen 8 0.0255 0.0414 0.2087
Entamoeba histolytica pyrophosphate-dependent phosphofructokinase 0.0029 0.0025 0.0124
Leishmania major hypothetical protein, conserved 0.0206 0.033 0.1595
Entamoeba histolytica hypothetical protein 0.0043 0.0049 0.0248
Echinococcus multilocularis nervana 2 0.002 0.0008 0.0008
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.075 0.1271 0.3951
Onchocerca volvulus 0.0023 0.0014 0.007
Entamoeba histolytica papain family cysteine protease domain containing protein 0.0255 0.0414 0.2095
Loa Loa (eye worm) hypothetical protein 0.0066 0.0089 0.0276
Echinococcus multilocularis cathepsin l cysteine peptidase 0.1158 0.1975 0.1975
Trypanosoma cruzi calmodulin, putative 0.0045 0.0052 0.0162
Trypanosoma cruzi I/6 autoantigen, putative 0.0045 0.0052 0.0162
Echinococcus multilocularis rhodopsin orphan GPCR 0.0095 0.0137 0.0137
Trypanosoma brucei CAMK/CAMKL family protein kinase, putative 0.0046 0.0053 0.0245
Echinococcus multilocularis dna polymerase kappa 0.0038 0.004 0.004
Leishmania major cysteine peptidase A (CPA) 0.1158 0.1975 0.9604
Schistosoma mansoni amine GPCR 0.0095 0.0137 0.0427
Echinococcus granulosus serine/threonine protein kinase 0.0022 0.0012 0.0012
Brugia malayi G-protein coupled receptor 0.0095 0.0137 0.0427
Trypanosoma brucei cysteine peptidase, Clan CA, family C2, putative 0.0301 0.0494 0.2395
Leishmania major small myristoylated protein-2 0.0648 0.1093 0.531
Loa Loa (eye worm) hypothetical protein 0.0095 0.0137 0.0427
Leishmania major META domain containing protein 0.0206 0.033 0.1595
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.075 0.1271 0.3951
Toxoplasma gondii microneme protein MIC17C 0.0042 0.0047 0.0236
Toxoplasma gondii AGC kinase 0.003 0.0026 0.0131
Echinococcus multilocularis dna polymerase eta 0.0063 0.0084 0.0084
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0457 0.0763 0.2374
Brugia malayi Nuclear hormone receptor-like 1 0.0021 0.001 0.0031
Trypanosoma cruzi cysteine protease, putative 0.0621 0.1047 0.3255
Mycobacterium tuberculosis Probable dehydrogenase 0.0108 0.016 0.2049
Echinococcus multilocularis dro:myosuppressin receptor 0.0095 0.0137 0.0137
Leishmania major centrin, putative,caltractin, putative 0.0045 0.0052 0.0243
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.06 0.1011 0.3143
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0751 0.1272 0.6181
Loa Loa (eye worm) hypothetical protein 0.0095 0.0137 0.0427
Echinococcus multilocularis thyroid hormone receptor alpha 0.0147 0.0227 0.0227
Plasmodium vivax plasmepsin V, putative 0.0145 0.0225 0.113
Leishmania major DNA polymerase eta, putative 0.0037 0.0038 0.0176
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.1205 0.2057 1
Echinococcus multilocularis enteropeptidase 0.0066 0.0089 0.0089
Onchocerca volvulus 0.1158 0.1975 1
Loa Loa (eye worm) low-density lipoprotein receptor repeat class B containing protein 0.0026 0.0019 0.006
Loa Loa (eye worm) hypothetical protein 0.0095 0.0137 0.0427
Schistosoma mansoni ancient conserved domain protein 2 (cyclin m2) 0.0095 0.0137 0.0427
Entamoeba histolytica cysteine protease, putative 0.0621 0.1047 0.53
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0018 0.0005 0.0012
Toxoplasma gondii eukaryotic aspartyl protease superfamily protein 0.0145 0.0225 0.114
Schistosoma mansoni rab geranylgeranyl transferase alpha subunit 0.0038 0.004 0.0123
Plasmodium vivax serine-repeat antigen 4 (SERA) 0.0255 0.0414 0.2087
Echinococcus multilocularis pyroglutamylated rfamide peptide receptor 0.0095 0.0137 0.0137
Leishmania major calcium channel protein, putative,ion transporter, putative 0.0041 0.0044 0.0204
Schistosoma mansoni family C2 unassigned peptidase (C02 family) 0.0962 0.1635 0.5085
Echinococcus multilocularis calpain A 0.1008 0.1715 0.1715
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0095 0.0137 0.0427
Trypanosoma cruzi CAMK/CAMKL family protein kinase, putative 0.0046 0.0053 0.0163
Schistosoma mansoni hypothetical protein 0.0017 0.0003 0.0008
Loa Loa (eye worm) calpain D 0.0251 0.0407 0.1267
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0615 0.1037 0.3223
Echinococcus granulosus rhodopsin orphan GPCR 0.0095 0.0137 0.0137
Echinococcus granulosus Ataxin 2 N terminaldomain containing protein 0.0024 0.0015 0.0015
Echinococcus granulosus cpg binding protein 0.0031 0.0028 0.0028
Brugia malayi larval opioid receptor 0.0095 0.0137 0.0427
Schistosoma mansoni cercarial elastase (S01 family) 0.0066 0.0089 0.0276
Echinococcus granulosus sex peptide receptor 0.0095 0.0137 0.0137
Entamoeba histolytica cysteine protease, putative 0.0621 0.1047 0.53
Leishmania major hypothetical protein, conserved 0.0206 0.033 0.1595
Trichomonas vaginalis AGC family protein kinase 0.0032 0.003 0.0138
Echinococcus multilocularis cathepsin d (lysosomal aspartyl protease) 0.0615 0.1037 0.1037
Toxoplasma gondii thioredoxin reductase 0.0047 0.0056 0.0281
Entamoeba histolytica EF-hand calcium-binding domain containing protein 0.0045 0.0052 0.0264
Loa Loa (eye worm) hypothetical protein 0.0095 0.0137 0.0427
Schistosoma mansoni blooms syndrome DNA helicase 0.0027 0.0021 0.0064
Brugia malayi G protein-coupled receptor F59B2.13 0.0095 0.0137 0.0427
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.1158 0.1975 1
Schistosoma mansoni hypothetical protein 0.0024 0.0015 0.0046
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0018 0.0005 0.0012
Schistosoma mansoni egf-like domain protein 0.0026 0.0019 0.006
Treponema pallidum exodeoxyribonuclease (exoA) 0.0038 0.0039 0.2412
Loa Loa (eye worm) hypothetical protein 0.0072 0.0099 0.0309
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0061 0.0079 0.0245
Echinococcus granulosus cathepsin d lysosomal aspartyl protease 0.0615 0.1037 0.1037
Plasmodium vivax serine-repeat antigen 5 (SERA) 0.0255 0.0414 0.2087
Trypanosoma cruzi C-8 sterol isomerase, putative 0.0359 0.0594 0.1846
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0017 0.0003 0.0008
Onchocerca volvulus 0.0095 0.0137 0.0696
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0301 0.0494 0.1537
Trypanosoma cruzi Present in the outer mitochondrial membrane proteome 33 0.0046 0.0054 0.0167
Schistosoma mansoni hypothetical protein 0.0052 0.0063 0.0197
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.0021 0.001 0.0031
Loa Loa (eye worm) hypothetical protein 0.0255 0.0414 0.1287
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0568 0.0956 0.4641
Entamoeba histolytica cysteine protease, putative 0.1158 0.1975 1
Schistosoma mansoni lamin 0.0056 0.007 0.0217
Onchocerca volvulus 0.1158 0.1975 1
Echinococcus multilocularis chromobox protein 1 0.0067 0.0091 0.0091
Onchocerca volvulus 0.1158 0.1975 1
Echinococcus multilocularis G protein coupled 5 hydroxytryptamine receptor 0.0095 0.0137 0.0137
Echinococcus multilocularis calpain 7 (C02 family) 0.0489 0.0819 0.0819
Giardia lamblia DINP protein human, muc B family 0.0038 0.004 0.0292
Toxoplasma gondii aspartyl protease 0.0145 0.0225 0.114
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0052 0.0065 0.0201
Echinococcus granulosus EF HAND 1 calcium binding site 0.0045 0.0052 0.0052
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0366 0.0607 0.1888
Plasmodium falciparum cysteine repeat modular protein 1 0.0134 0.0206 0.1031
Trypanosoma brucei I/6 autoantigen 0.0045 0.0052 0.0243
Brugia malayi AKH receptor 0.0095 0.0137 0.0427
Echinococcus granulosus neuropeptide Y receptor 0.0095 0.0137 0.0137
Loa Loa (eye worm) fibroinase 0.1158 0.1975 0.6142
Mycobacterium tuberculosis Probable membrane NADH dehydrogenase NdhA 0.0108 0.016 0.2049
Trichomonas vaginalis calmodulin, putative 0.0045 0.0052 0.0253
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0021 0.001 0.0031
Onchocerca volvulus Dopamine\/Ecdysteroid receptor homolog 0.0095 0.0137 0.0696
Echinococcus multilocularis somatostatin receptor 0.0095 0.0137 0.0137
Trichomonas vaginalis AGC family protein kinase 0.0032 0.003 0.0138
Loa Loa (eye worm) cysteine protease 0.1158 0.1975 0.6142
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.0038 0.0039 0.0121
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.0021 0.001 0.0031
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0489 0.0819 0.2547
Brugia malayi Trypsin family protein 0.0066 0.0089 0.0276
Brugia malayi calpain family protein 1 0.0962 0.1635 0.5085
Trichomonas vaginalis hypothetical protein 0.0251 0.0407 0.2053
Entamoeba histolytica recQ family helicase, putative 0.0032 0.003 0.015
Trichomonas vaginalis chromobox protein, putative 0.0041 0.0044 0.0213
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0512 0.0859 0.4168
Echinococcus multilocularis peptide (allatostatin:somatostatin) 0.0095 0.0137 0.0137
Plasmodium vivax calcium-dependent protein kinase 3, putative 0.0046 0.0053 0.0255
Schistosoma mansoni opsin-like receptor 0.0095 0.0137 0.0427
Plasmodium falciparum cysteine proteinase falcipain 3 0.1158 0.1975 1
Brugia malayi cathepsin B-like cysteine proteinase 0.1876 0.3216 1
Schistosoma mansoni nuclear hormone receptor 0.0021 0.001 0.003
Schistosoma mansoni neuronal calcium sensor 0.0045 0.0052 0.0162
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.0021 0.001 0.001
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0095 0.0137 0.0427
Trichomonas vaginalis conserved hypothetical protein 0.0045 0.0052 0.0253
Loa Loa (eye worm) hypothetical protein 0.0056 0.007 0.0218
Echinococcus multilocularis sodium channel protein 0.0041 0.0044 0.0044
Brugia malayi hypothetical protein 0.0095 0.0137 0.0427
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0255 0.0414 0.2087
Trypanosoma brucei hypothetical protein, conserved 0.0072 0.0099 0.0472
Trypanosoma brucei cysteine peptidase, Clan CA, family C2, putative 0.0794 0.1347 0.6544
Loa Loa (eye worm) G-protein coupled receptor 0.0095 0.0137 0.0427
Mycobacterium ulcerans hypothetical protein 0.0066 0.0089 0.5446
Echinococcus granulosus neuronal calcium sensor 0.0045 0.0052 0.0052
Echinococcus granulosus calcium:calmodulin dependent protein kinase 0.002 0.0009 0.0009
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0061 0.0079 0.0079
Trypanosoma cruzi cysteine proteinase, putative 0.0621 0.1047 0.3255
Schistosoma mansoni tar DNA-binding protein 0.0067 0.0089 0.0277
Echinococcus granulosus serine threonine protein kinase nrc 0.002 0.0009 0.0009
Schistosoma mansoni notch 0.0015 0 0.0000086345
Echinococcus granulosus chromobox protein 1 0.0067 0.0091 0.0091
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0018 0.0005 0.0012
Trypanosoma cruzi cysteine peptidase, putative 0.1158 0.1975 0.6142
Trypanosoma cruzi ATP-dependent 6-phosphofructokinase, glycosomal 0.0108 0.0161 0.0501
Loa Loa (eye worm) hypothetical protein 0.0042 0.0047 0.0145
Loa Loa (eye worm) hypothetical protein 0.0028 0.0022 0.0068
Toxoplasma gondii hypothetical protein 0.0042 0.0047 0.0236
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0072 0.0099 0.0309
Trichomonas vaginalis conserved hypothetical protein 0.0255 0.0414 0.2087
Brugia malayi p70 ribosomal S6 kinase beta 0.003 0.0026 0.0081
Schistosoma mansoni adenoreceptor 0.0095 0.0137 0.0427
Echinococcus granulosus EF hand domain containing family member A2 0.0045 0.0052 0.0052
Echinococcus granulosus cathepsin L 0.0255 0.0414 0.0414
Loa Loa (eye worm) hypothetical protein 0.0042 0.0047 0.0145
Schistosoma mansoni matrix metallopeptidase-7 (M10 family) 0.0023 0.0014 0.0043
Brugia malayi hypothetical protein 0.0236 0.0381 0.1185
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0678 0.1145 0.3559
Brugia malayi MH2 domain containing protein 0.0144 0.0223 0.0694
Echinococcus granulosus hypothetical protein 0.0095 0.0137 0.0137
Loa Loa (eye worm) hypothetical protein 0.0095 0.0137 0.0427
Onchocerca volvulus Heterochromatin protein 1 homolog 0.0038 0.0039 0.0199
Trichomonas vaginalis penicillin-binding protein, putative 0.0072 0.0099 0.0491
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0457 0.0763 0.2374
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0692 0.1171 0.5687
Echinococcus multilocularis Tolloid protein 1 0.0026 0.0019 0.0019
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.1158 0.1975 1
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.1158 0.1975 1
Plasmodium falciparum plasmepsin VII 0.0145 0.0225 0.113
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0188 0.0298 0.0927
Brugia malayi PAN domain containing protein 0.0042 0.0047 0.0145
Brugia malayi hypothetical protein 0.0095 0.0137 0.0427
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0301 0.0494 0.1537
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0261 0.0425 0.1322
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.1158 0.1975 1
Entamoeba histolytica calpain large subunit domain III containing protein 0.0238 0.0386 0.1953
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0061 0.0079 0.0399
Loa Loa (eye worm) hypothetical protein 0.0154 0.0241 0.0749
Loa Loa (eye worm) hypothetical protein 0.0325 0.0536 0.1666
Echinococcus multilocularis Glutaredoxin protein 5 0.002 0.0008 0.0008
Onchocerca volvulus 0.0095 0.0137 0.0696
Trypanosoma cruzi hypothetical protein, conserved 0.0134 0.0206 0.0639
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0255 0.0414 0.1287
Schistosoma mansoni biogenic amine receptor 0.0095 0.0137 0.0427
Schistosoma mansoni cathepsin s 0.0366 0.0607 0.1887
Echinococcus granulosus geminin 0.0348 0.0576 0.0576
Leishmania major cathepsin L-like protease 0.1205 0.2057 1
Entamoeba histolytica protein kinase, putative 0.0239 0.0386 0.1955
Brugia malayi hypothetical protein 0.0043 0.0049 0.0153
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.0021 0.001 0.003
Trypanosoma cruzi trypanothione reductase, putative 0.0016 0.0002 0.0007
Echinococcus granulosus centrin 2 0.0045 0.0052 0.0052
Brugia malayi aspartic protease BmAsp-2, identical 0.0145 0.0225 0.0701
Brugia malayi putative neuropeptide receptor NPR1 0.0095 0.0137 0.0427
Brugia malayi B-box zinc finger family protein 0.0031 0.0027 0.0084
Schistosoma mansoni hypothetical protein 0.0031 0.0027 0.0083
Loa Loa (eye worm) hypothetical protein 0.0095 0.0137 0.0427
Onchocerca volvulus 0.0066 0.0089 0.045
Trypanosoma cruzi hypothetical protein, conserved 0.0072 0.0099 0.0308
Echinococcus multilocularis thioredoxin glutathione reductase 0.0047 0.0056 0.0056
Onchocerca volvulus 0.0095 0.0137 0.0696
Giardia lamblia Hypothetical protein 0.0046 0.0054 0.0404
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0188 0.0298 0.0298
Loa Loa (eye worm) programmed cell death protein 6 0.0046 0.0054 0.0168
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0255 0.0414 0.2087
Loa Loa (eye worm) hypothetical protein 0.0095 0.0137 0.0427
Plasmodium falciparum serine repeat antigen 7 0.0255 0.0414 0.2087
Loa Loa (eye worm) steroid hormone receptor 0.0021 0.001 0.0031
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0255 0.0414 0.2087
Echinococcus granulosus neuropeptide receptor 0.0095 0.0137 0.0137
Brugia malayi Papain family cysteine protease containing protein 0.0255 0.0414 0.1287
Trichomonas vaginalis DNA polymerase IV / kappa, putative 0.0038 0.004 0.0189
Trypanosoma cruzi cytochrome P450, putative 0.0033 0.0031 0.0095
Loa Loa (eye worm) hypothetical protein 0.0154 0.0241 0.0749
Loa Loa (eye worm) hypothetical protein 0.0027 0.002 0.0063
Brugia malayi Nuclear hormone receptor family member nhr-3 0.0021 0.001 0.0031
Echinococcus granulosus peptidyl glycine alpha amidating monooxygenase 0.1169 0.1994 0.1994
Giardia lamblia Cysteine protease 0.0255 0.0414 0.3221
Trypanosoma cruzi cytoskeleton-associated protein CAP5.5, putative 0.0457 0.0763 0.2374
Onchocerca volvulus 0.0255 0.0414 0.2096
Brugia malayi Matrixin family protein 0.0056 0.007 0.0219
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0016 0.0002 0.0007
Trypanosoma cruzi hypothetical protein, conserved 0.0206 0.033 0.1026
Echinococcus multilocularis calpain 0.0489 0.0819 0.0819
Schistosoma mansoni tar DNA-binding protein 0.0067 0.0089 0.0277
Loa Loa (eye worm) hypothetical protein 0.0255 0.0414 0.1287
Schistosoma mansoni hypothetical protein 0.0031 0.0027 0.0083
Trichomonas vaginalis centrin, putative 0.0045 0.0052 0.0253
Brugia malayi nuclear receptor NHR-88 0.0021 0.001 0.0031
Schistosoma mansoni neuropeptide receptor 0.0095 0.0137 0.0427
Schistosoma mansoni serine/threonine-protein kinase 0.0022 0.0012 0.0037
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0021 0.001 0.0031
Echinococcus granulosus cathepsin L cysteine protease 0.0621 0.1047 0.1047
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0018 0.0005 0.0012
Trypanosoma cruzi caltractin, putative 0.0045 0.0052 0.0162
Schistosoma mansoni amine GPCR 0.0095 0.0137 0.0427
Trichomonas vaginalis phosphofructokinase, putative 0.0029 0.0025 0.0113
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0489 0.0819 0.2547
Loa Loa (eye worm) glutathione reductase 0.0047 0.0056 0.0173
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0188 0.0298 0.0298
Loa Loa (eye worm) hypothetical protein 0.0255 0.0414 0.1287
Echinococcus granulosus matrix metallopeptidase 7 M10 family 0.0084 0.0119 0.0119
Brugia malayi Matrixin family protein 0.0023 0.0014 0.0043
Loa Loa (eye worm) hypothetical protein 0.0072 0.0099 0.0309
Brugia malayi G protein-coupled receptor 0.0095 0.0137 0.0427
Mycobacterium tuberculosis Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras 0.012 0.0181 0.2318
Entamoeba histolytica hypothetical protein 0.0043 0.0049 0.0248
Trichomonas vaginalis calmodulin-2, putative 0.0045 0.0052 0.0253
Trypanosoma cruzi centrin, putative 0.0053 0.0066 0.0206
Brugia malayi Trypsin family protein 0.0325 0.0536 0.1666
Brugia malayi ORL1-like opioid receptor 0.0095 0.0137 0.0427
Brugia malayi Serotonin receptor 0.0095 0.0137 0.0427
Echinococcus granulosus calpain A 0.1008 0.1715 0.1715
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.0021 0.001 0.005
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0095 0.0137 0.0427
Leishmania major isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0017 0.0003 0.0002
Entamoeba histolytica cysteine protease, putative 0.0255 0.0414 0.2095
Onchocerca volvulus 0.0072 0.0099 0.0503
Loa Loa (eye worm) cytochrome P450 family protein 0.0033 0.0031 0.0096
Loa Loa (eye worm) PAN domain-containing protein 0.0042 0.0047 0.0145
Trypanosoma brucei cysteine peptidase, Clan CA, family C2, putative 0.0251 0.0407 0.1972
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0066 0.0089 0.0276
Entamoeba histolytica prefoldin subunit 6, putative 0.0103 0.0152 0.0767
Brugia malayi hypothetical protein 0.0122 0.0184 0.0573
Onchocerca volvulus 0.0046 0.0054 0.0273
Toxoplasma gondii hypothetical protein 0.0251 0.0407 0.2062
Trypanosoma brucei flagellum-adhesion glycoprotein, putative 0.0031 0.0027 0.0119
Leishmania major ATP-dependent DEAD/H DNA helicase recQ, putative 0.0032 0.003 0.0133
Trichomonas vaginalis centrin, putative 0.0045 0.0052 0.0253
Brugia malayi PAN domain containing protein 0.0042 0.0047 0.0145
Loa Loa (eye worm) hypothetical protein 0.0723 0.1223 0.3804
Schistosoma mansoni hypothetical protein 0.0031 0.0027 0.0083
Giardia lamblia Dipeptidyl-peptidase I precursor 0.0255 0.0414 0.3221
Brugia malayi beta-lactamase 0.0072 0.0099 0.0309
Echinococcus multilocularis cathepsin b 0.1876 0.3216 0.3216
Schistosoma mansoni histamine-responsive GPCR (AAF21638) 0.0095 0.0137 0.0427
Echinococcus granulosus rhodopsin orphan GPCR 0.0095 0.0137 0.0137
Schistosoma mansoni cathepsin S (C01 family) 0.0255 0.0414 0.1287
Schistosoma mansoni Tr4/Tr2 (homologue) 0.0021 0.001 0.003
Trichomonas vaginalis phosphofructokinase, putative 0.0029 0.0025 0.0113
Brugia malayi calpain family protein 1 0.0962 0.1635 0.5085
Brugia malayi calpain 5 0.0251 0.0407 0.1267
Echinococcus granulosus dna polymerase kappa 0.0038 0.004 0.004
Mycobacterium tuberculosis Conserved protein 0.0072 0.0099 0.1256
Schistosoma mansoni subfamily C1A unassigned peptidase (C01 family) 0.0255 0.0414 0.1287
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0255 0.0414 0.2087
Plasmodium falciparum ATP-dependent DNA helicase Q1 0.003 0.0025 0.0116
Brugia malayi dihydrolipoyl dehydrogenase, mitochondrial precursor, putative 0.0016 0.0002 0.0007
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0017 0.0003 0.0003
Plasmodium vivax thioredoxin reductase, putative 0.0047 0.0056 0.0271
Mycobacterium tuberculosis Probable esterase LipL 0.0072 0.0099 0.1256
Onchocerca volvulus 0.0478 0.0799 0.4045
Trypanosoma cruzi cysteine peptidase C (CPC), putative 0.1876 0.3216 1
Trypanosoma cruzi cytochrome P450, putative 0.0033 0.0031 0.0095
Schistosoma mansoni growth hormone secretagogue receptor 0.0095 0.0137 0.0427
Loa Loa (eye worm) hypothetical protein 0.0095 0.0137 0.0427
Echinococcus granulosus calbindin 32 0.0046 0.0054 0.0054
Echinococcus multilocularis calcium uptake protein 1 0.0046 0.0054 0.0054
Trichomonas vaginalis phosphofructokinase, putative 0.0029 0.0025 0.0113
Echinococcus multilocularis biogenic amine (5HT) receptor 0.0095 0.0137 0.0137
Leishmania major i/6 autoantigen-like protein 0.0045 0.0052 0.0243
Entamoeba histolytica cysteine protease, putative 0.0621 0.1047 0.53
Echinococcus granulosus cathepsin b 0.1876 0.3216 0.3216
Leishmania major programmed cell death 6 protein-like protein 0.0045 0.0052 0.0243
Schistosoma mansoni cercarial elastase (S01 family) 0.0066 0.0089 0.0276
Plasmodium vivax serine-repeat antigen (SERA), putative 0.0255 0.0414 0.2087
Leishmania major cathepsin L-like protease 0.1158 0.1975 0.9604
Brugia malayi RNA recognition motif domain containing protein 0.0067 0.0089 0.0277
Plasmodium vivax ataxin-2 like protein, putative 0.0053 0.0065 0.0317
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.1205 0.2057 1
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.0021 0.001 0.0031
Brugia malayi ecdysteroid receptor 0.0021 0.001 0.0031
Entamoeba histolytica cysteine protease, putative 0.0255 0.0414 0.2095
Chlamydia trachomatis fructose-6-phosphate phosphotransferase 0.0029 0.0025 1
Loa Loa (eye worm) cysteine proteinase cathepsin Z 0.0255 0.0414 0.1287
Loa Loa (eye worm) hypothetical protein 0.0026 0.0019 0.006
Schistosoma mansoni family C2 unassigned peptidase (C02 family) 0.1007 0.1714 0.5328
Brugia malayi Papain family cysteine protease containing protein 0.0621 0.1047 0.3256
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0016 0.0002 0.0007
Trypanosoma brucei cysteine peptidase, Clan CA, family C2, putative 0.0301 0.0494 0.2395
Brugia malayi Papain family cysteine protease containing protein 0.0621 0.1047 0.3256
Giardia lamblia Cathepsin L-like protease 0.0255 0.0414 0.3221
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0061 0.0079 0.0079
Onchocerca volvulus 0.0095 0.0137 0.0696
Schistosoma mansoni hypothetical protein 0.0045 0.0052 0.0162
Loa Loa (eye worm) hypothetical protein 0.0042 0.0047 0.0145
Trypanosoma brucei calpain-like protein, putative 0.0489 0.0819 0.3977
Brugia malayi Steroid receptor seven-up type 2 0.0021 0.001 0.0031
Loa Loa (eye worm) hypothetical protein 0.0095 0.0137 0.0427
Brugia malayi Calmodulin-like protein 0.0045 0.0052 0.0163
Echinococcus multilocularis FTZ F1 alpha 0.0021 0.001 0.001
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0016 0.0002 0.0007
Schistosoma mansoni histamine h1 receptor 0.0095 0.0137 0.0427
Loa Loa (eye worm) hypothetical protein 0.0061 0.0079 0.0246
Echinococcus multilocularis calumenin 0.0046 0.0054 0.0054
Loa Loa (eye worm) hypothetical protein 0.0103 0.0152 0.0472
Echinococcus multilocularis isocitrate dehydrogenase 2 (NADP+) 0.0017 0.0003 0.0003
Giardia lamblia Kinase, AGC PKA 0.002 0.0009 0.0049
Schistosoma mansoni cpg binding protein 0.0031 0.0028 0.0088
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0255 0.0414 0.2087
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0255 0.0414 0.1287
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.0021 0.001 0.003
Trypanosoma brucei calmodulin, putative 0.0046 0.0054 0.0251
Loa Loa (eye worm) hypothetical protein 0.0026 0.0019 0.0058
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0095 0.0137 0.0137
Schistosoma mansoni hypothetical protein 0.0036 0.0036 0.0111
Plasmodium vivax ADP-dependent DNA helicase RecQ, putative 0.0025 0.0017 0.0076
Brugia malayi glutathione reductase 0.0047 0.0056 0.0173
Trichomonas vaginalis calmodulin, putative 0.0053 0.0066 0.0324
Trypanosoma brucei isocitrate dehydrogenase, putative 0.0017 0.0003 0.0002
Echinococcus multilocularis 6 phosphofructokinase 0.0108 0.0161 0.0161
Trypanosoma cruzi ATP-dependent DEAD/H DNA helicase recQ, putative 0.0032 0.003 0.0092
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0376 0.0624 0.1941
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.0048 0.0057 0.0178
Echinococcus multilocularis beta LACTamase domain containing family member 0.0072 0.0099 0.0099
Echinococcus multilocularis chromobox protein 1 0.0067 0.0091 0.0091
Onchocerca volvulus 0.0042 0.0047 0.0237
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.0038 0.0039 0.0121
Loa Loa (eye worm) hypothetical protein 0.0095 0.0137 0.0427
Echinococcus granulosus beta LACTamase domain containing family member 0.0072 0.0099 0.0099
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.1158 0.1975 1
Brugia malayi Matrixin family protein 0.0023 0.0014 0.0043
Echinococcus granulosus rhodopsin orphan GPCR 0.0095 0.0137 0.0137
Trichomonas vaginalis conserved hypothetical protein 0.0334 0.0551 0.278
Schistosoma mansoni peptidylglycine monooxygenase 0.0621 0.1047 0.3256
Trypanosoma cruzi rac serine-threonine kinase, putative 0.002 0.0009 0.0026
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0439 0.0733 0.3555
Mycobacterium leprae Probable lipase LipE 0.0072 0.0099 0.4832
Plasmodium falciparum plasmepsin IX 0.0145 0.0225 0.113
Loa Loa (eye worm) hypothetical protein 0.0615 0.1037 0.3224
Trypanosoma brucei small myristoylated protein 1-1 0.0355 0.0588 0.2852
Toxoplasma gondii EFHC1, putative 0.0045 0.0052 0.0264
Echinococcus multilocularis muscleblind protein 0.0154 0.0241 0.0241
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0582 0.098 0.4761
Loa Loa (eye worm) hypothetical protein 0.0095 0.0137 0.0427
Entamoeba histolytica cysteine proteinase, putative 0.0621 0.1047 0.53
Trichomonas vaginalis myosin light chain 1, putative 0.0045 0.0052 0.0253
Entamoeba histolytica cysteine proteinase, putative 0.1158 0.1975 1
Echinococcus multilocularis rac serine:threonine kinase 0.0022 0.0012 0.0012
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.1158 0.1975 1
Brugia malayi EF hand family protein 0.0046 0.0054 0.0168
Toxoplasma gondii cathepsin CPC2 0.0255 0.0414 0.2095
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.0021 0.001 0.001
Brugia malayi ATP-dependent DNA helicase, RecQ family protein 0.003 0.0025 0.0079
Leishmania major calmodulin-like protein 0.0045 0.0052 0.0243
Loa Loa (eye worm) hypothetical protein 0.0095 0.0137 0.0427
Toxoplasma gondii histone lysine methyltransferase SET1 0.0059 0.0075 0.038
Brugia malayi Dopamine receptor protein 1, putative (partial) 0.0095 0.0137 0.0427
Brugia malayi B-box type zinc-finger protein ncl-1 0.0031 0.0027 0.0084
Loa Loa (eye worm) hypothetical protein 0.0045 0.0052 0.0163
Plasmodium vivax serine-repeat antigen (SERA) 0.0255 0.0414 0.2087
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0016 0.0002 0.0007
Loa Loa (eye worm) hypothetical protein 0.0021 0.001 0.0031
Loa Loa (eye worm) hypothetical protein 0.0792 0.1342 0.4174
Echinococcus multilocularis microtubule associated protein 2 0.0726 0.1228 0.1228
Plasmodium vivax aspartyl proteinase, putative 0.0145 0.0225 0.113
Trypanosoma cruzi cysteine peptidase, putative 0.1205 0.2057 0.6395
Schistosoma mansoni alpha-1 adrenergic receptor 0.0095 0.0137 0.0427
Loa Loa (eye worm) hypothetical protein 0.0066 0.0089 0.0276
Echinococcus granulosus g protein coupled receptor 0.0095 0.0137 0.0137
Trichomonas vaginalis Clan CA, family C2, calpain-like cysteine peptidase 0.0251 0.0407 0.2053
Toxoplasma gondii aspartyl protease ASP3 0.0145 0.0225 0.114
Brugia malayi Nuclear hormone receptor family member nhr-49 0.0021 0.001 0.0031
Echinococcus multilocularis tachykinin peptides receptor 99D 0.5803 1 1
Schistosoma mansoni hypothetical protein 0.0126 0.0192 0.0595
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0621 0.1047 0.5295
Trypanosoma brucei calpain-like cysteine peptidase, putative 0.0261 0.0425 0.2059
Loa Loa (eye worm) hypothetical protein 0.0621 0.1047 0.3256
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0255 0.0414 0.2087
Trypanosoma brucei DNA polymerase kappa, putative 0.0038 0.004 0.0182
Entamoeba histolytica cysteine protease, putative 0.0621 0.1047 0.53
Echinococcus multilocularis nuclear factor of activated T cells 5 0.0074 0.0101 0.0101
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0043 0.0049 0.0049
Trypanosoma brucei unspecified product 0.0026 0.0019 0.0083
Echinococcus multilocularis Ataxin 2, N terminal,domain containing protein 0.0024 0.0015 0.0015
Echinococcus multilocularis prefoldin subunit 6 0.0103 0.0152 0.0152
Schistosoma mansoni hypothetical protein 0.0348 0.0576 0.179
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0255 0.0414 0.2087
Schistosoma mansoni steroid hormone receptor ad4bp 0.0021 0.001 0.003
Leishmania major hypothetical protein, conserved 0.0072 0.0099 0.0472
Echinococcus multilocularis sex peptide receptor 0.0095 0.0137 0.0137
Toxoplasma gondii troponin c, isotype gamma, putative 0.0045 0.0052 0.0264
Entamoeba histolytica cysteine protease, putative 0.0255 0.0414 0.2095
Brugia malayi Papain family cysteine protease containing protein 0.0255 0.0414 0.1287
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.0621 0.1047 0.3255
Entamoeba histolytica calmodulin, putative 0.0045 0.0052 0.0264
Mycobacterium tuberculosis Probable conserved membrane protein 0.0031 0.0027 0.0317
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.1205 0.2057 1
Giardia lamblia Dipeptidyl-peptidase I precursor 0.0255 0.0414 0.3221
Trypanosoma brucei Calpain-like protein 1.1 0.0794 0.1347 0.6544
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.0021 0.001 0.001
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0043 0.0049 0.0049
Schistosoma mansoni neuronal calcium sensor 0.0045 0.0052 0.0162
Toxoplasma gondii PAN domain-containing protein 0.0042 0.0047 0.0236
Schistosoma mansoni biogenic amine receptor 0.0095 0.0137 0.0427
Loa Loa (eye worm) hypothetical protein 0.003 0.0025 0.0079
Toxoplasma gondii NADPH-glutathione reductase 0.0016 0.0002 0.0011
Mycobacterium ulcerans esterase/lipase LipP 0.0072 0.0099 0.6099
Echinococcus multilocularis EF hand domain containing family member A2 0.0046 0.0054 0.0054
Loa Loa (eye worm) PAN domain-containing protein 0.0042 0.0047 0.0145
Mycobacterium tuberculosis PE-PGRS family protein PE_PGRS17 0.0031 0.0027 0.0317
Schistosoma mansoni neuropeptide receptor 0.0095 0.0137 0.0427
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.1158 0.1975 1
Plasmodium vivax calpain, putative 0.0489 0.0819 0.4141
Echinococcus granulosus sodium:potassium dependent atpase beta subunit 0.002 0.0008 0.0008
Brugia malayi programmed cell death protein 6 0.0045 0.0052 0.0163
Trichomonas vaginalis calcineurin B subunit, putative 0.0045 0.0052 0.0253
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0095 0.0137 0.0427
Echinococcus multilocularis cathepsin L 0.0621 0.1047 0.1047
Onchocerca volvulus 0.0095 0.0137 0.0696
Trichomonas vaginalis chromobox protein, putative 0.0067 0.0091 0.0447
Plasmodium vivax dipeptidyl aminopeptidase 1, putative 0.0255 0.0414 0.2087
Schistosoma mansoni tar DNA-binding protein 0.0067 0.0089 0.0277
Schistosoma mansoni intermediate filament proteins 0.0056 0.007 0.0217
Brugia malayi cathepsin F-like cysteine proteinase 0.0366 0.0607 0.1888
Echinococcus granulosus neurocalcin 0.0045 0.0052 0.0052
Echinococcus multilocularis fmrfamide receptor 0.0095 0.0137 0.0137
Onchocerca volvulus 0.016 0.025 0.1267
Trichomonas vaginalis conserved hypothetical protein 0.0027 0.002 0.0091
Entamoeba histolytica cysteine proteinase 2 0.0621 0.1047 0.53
Loa Loa (eye worm) thioredoxin reductase 0.0047 0.0056 0.0173
Onchocerca volvulus 0.0095 0.0137 0.0696
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.0021 0.001 0.0031
Trypanosoma brucei calpain-like protein, putative 0.0489 0.0819 0.3977
Onchocerca volvulus 0.0095 0.0137 0.0696
Schistosoma mansoni serine/threonine-protein kinase 0.0022 0.0012 0.0037
Echinococcus granulosus neuropeptides capa receptor 0.0095 0.0137 0.0137
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0018 0.0005 0.0012
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0072 0.0099 0.0308
Entamoeba histolytica cysteine proteinase 1, putative 0.0621 0.1047 0.53
Brugia malayi RNA binding protein 0.0067 0.0089 0.0277
Trypanosoma cruzi Present in the outer mitochondrial membrane proteome 33 0.0045 0.0052 0.0162
Loa Loa (eye worm) hypothetical protein 0.0072 0.0099 0.0309
Trypanosoma cruzi DNA polymerase kappa, putative 0.0038 0.004 0.0123
Brugia malayi Intermediate filament tail domain containing protein 0.0056 0.007 0.0218
Leishmania major hypothetical protein, conserved 0.0053 0.0065 0.0305
Brugia malayi Trypsin family protein 0.0066 0.0089 0.0276
Trypanosoma brucei ATP-dependent DEAD/H DNA helicase recQ, putative 0.0032 0.003 0.0133
Schistosoma mansoni NADP-specific isocitrate dehydrogenase 0.0017 0.0003 0.0008
Entamoeba histolytica protein kinase, putative 0.003 0.0026 0.0131
Loa Loa (eye worm) hypothetical protein 0.0095 0.0137 0.0427
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.1158 0.1975 1
Schistosoma mansoni hypothetical protein 0.0031 0.0027 0.0083
Brugia malayi Fibulin-1 precursor 0.0026 0.0019 0.006
Schistosoma mansoni amine GPCR 0.0095 0.0137 0.0427
Plasmodium falciparum plasmepsin VI 0.0615 0.1037 0.5243
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.1158 0.1975 1
Loa Loa (eye worm) 6-phosphofructokinase 0.0108 0.0161 0.0501
Trypanosoma cruzi I/6 autoantigen, putative 0.0045 0.0052 0.0162
Giardia lamblia Cysteine protease 0.0255 0.0414 0.3221
Echinococcus granulosus rhodopsin orphan GPCR 0.0095 0.0137 0.0137
Echinococcus multilocularis calmodulin 0.0045 0.0052 0.0052
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0095 0.0137 0.0427
Leishmania major cathepsin L-like protease 0.1158 0.1975 0.9604
Schistosoma mansoni cathepsin D (A01 family) 0.1675 0.2867 0.8916
Loa Loa (eye worm) hypothetical protein 0.0042 0.0047 0.0145
Trypanosoma cruzi PAB1-binding protein , putative 0.0053 0.0065 0.0202
Toxoplasma gondii prefoldin subunit 6, putative 0.0103 0.0152 0.0767
Onchocerca volvulus 0.0021 0.001 0.005
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0017 0.0003 0.0003
Leishmania major centrin, putative 0.0045 0.0052 0.0243
Toxoplasma gondii phosphofructokinase PFKII 0.0029 0.0025 0.0124
Toxoplasma gondii preprocathepsin c precursor, putative 0.0255 0.0414 0.2095
Schistosoma mansoni hypothetical protein 0.0066 0.0089 0.0276
Brugia malayi Serotonin/octopamine receptor family protein 7 0.0095 0.0137 0.0427
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.06 0.1011 0.491
Toxoplasma gondii PAN domain-containing protein 0.0042 0.0047 0.0236
Brugia malayi B-box zinc finger family protein 0.0031 0.0027 0.0084
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.1205 0.2057 1
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0439 0.0733 0.2278
Schistosoma mansoni cathepsin F (C01 family) 0.1158 0.1975 0.6142
Trypanosoma cruzi cytoskeleton-associated protein CAP5.5, putative 0.0457 0.0763 0.2374
Loa Loa (eye worm) hypothetical protein 0.0359 0.0594 0.1847
Onchocerca volvulus 0.003 0.0025 0.0129
Echinococcus granulosus intermediate filament protein 0.0056 0.007 0.007
Onchocerca volvulus 0.0095 0.0137 0.0696
Schistosoma mansoni dihydrolipoamide dehydrogenase 0.0016 0.0002 0.0007
Onchocerca volvulus Neuropeptide F receptor homolog 0.0095 0.0137 0.0696
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.0021 0.001 0.001
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0544 0.0913 0.2839
Mycobacterium ulcerans hypothetical protein 0.0072 0.0099 0.6099
Trypanosoma brucei calpain-like cysteine peptidase, putative 0.0261 0.0425 0.2059
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.1205 0.2057 1
Plasmodium falciparum isocitrate dehydrogenase [NADP], mitochondrial 0.0017 0.0003 0.0002
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0018 0.0005 0.0012
Brugia malayi Calcium binding EGF domain containing protein 0.0026 0.0019 0.006
Trichomonas vaginalis Clan CA, family C2, calpain-like cysteine peptidase 0.0251 0.0407 0.2053
Loa Loa (eye worm) hypothetical protein 0.0095 0.0137 0.0427
Loa Loa (eye worm) hypothetical protein 0.0054 0.0068 0.0212
Loa Loa (eye worm) hypothetical protein 0.0317 0.0522 0.1624
Trypanosoma cruzi cysteine peptidase C (CPC), putative 0.0756 0.1281 0.3982
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.0021 0.001 0.001
Plasmodium falciparum plasmepsin IV 0.0615 0.1037 0.5243
Onchocerca volvulus 0.0042 0.0047 0.0237
Trypanosoma brucei cysteine peptidase, Clan CA, family C2, putative 0.0678 0.1145 0.5561
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.0024 0.0016 0.0082
Entamoeba histolytica phosphofructokinase, putative 0.0108 0.0161 0.0815
Leishmania major cytoskeleton-associated protein CAP5.5, putative,cysteine peptidase, Clan CA, family C2, putative 0.0457 0.0763 0.3705
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.1158 0.1975 1
Onchocerca volvulus Arrow homolog 0.0026 0.0019 0.0098
Trichomonas vaginalis chromobox protein, putative 0.0041 0.0044 0.0213
Trichomonas vaginalis chromobox protein, putative 0.0067 0.0091 0.0447
Trichomonas vaginalis AGC family protein kinase 0.0032 0.003 0.0138
Echinococcus multilocularis cathepsin L cysteine protease 0.1158 0.1975 0.1975
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0018 0.0005 0.0012
Loa Loa (eye worm) PAN domain-containing protein 0.0042 0.0047 0.0145
Trichomonas vaginalis calmodulin, putative 0.0045 0.0052 0.0253
Entamoeba histolytica protein kinase 2, putative 0.002 0.0009 0.0043
Trichomonas vaginalis DNA helicase recq, putative 0.0042 0.0047 0.0226
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0016 0.0002 0.0007
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0621 0.1047 0.5295
Trichomonas vaginalis DNA-dependent protein kinase catalytic subunit-interacting protein, putative 0.0045 0.0052 0.0253
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0255 0.0414 0.1287
Schistosoma mansoni dopamine-beta-monooxygenase 0.0621 0.1047 0.3256
Loa Loa (eye worm) hypothetical protein 0.0145 0.0225 0.0701
Schistosoma mansoni reticulocalbin 0.0046 0.0054 0.0167
Trichomonas vaginalis conserved hypothetical protein 0.0045 0.0052 0.0253
Echinococcus granulosus neuropeptides capa receptor 0.0095 0.0137 0.0137
Brugia malayi cytoplasmic intermediate filament protein 0.003 0.0025 0.0079
Echinococcus granulosus biogenic amine 5HT receptor 0.0095 0.0137 0.0137
Echinococcus multilocularis rhodopsin orphan GPCR 0.0095 0.0137 0.0137
Schistosoma mansoni hypothetical protein 0.0043 0.0049 0.0152
Echinococcus granulosus survival motor neuron protein 1 0.0236 0.0381 0.0381
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0325 0.0536 0.1666
Loa Loa (eye worm) hypothetical protein 0.0021 0.001 0.0031
Onchocerca volvulus 0.0095 0.0137 0.0696
Loa Loa (eye worm) neuropeptide F receptor 0.0095 0.0137 0.0427
Onchocerca volvulus Matrix metalloproteinase homolog 0.0051 0.0062 0.0316
Onchocerca volvulus 0.0042 0.0047 0.0237
Entamoeba histolytica grainin, putative 0.0046 0.0054 0.0272
Schistosoma mansoni peptidyl-glycine monooxygenase 0.1169 0.1994 0.6202
Trypanosoma brucei cysteine peptidase C (CPC) 0.0756 0.1281 0.6222
Entamoeba histolytica cysteine protease, putative 0.0255 0.0414 0.2095
Brugia malayi hypothetical protein 0.0095 0.0137 0.0427
Brugia malayi EF hand family protein 0.0045 0.0052 0.0163
Schistosoma mansoni calpain-2 (C02 family) 0.0251 0.0407 0.1266
Loa Loa (eye worm) hypothetical protein 0.016 0.025 0.0778
Plasmodium falciparum serine repeat antigen 5 0.0255 0.0414 0.2087
Trypanosoma brucei calpain, putative 0.0512 0.0859 0.4168
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0756 0.1281 0.3982
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.003 0.0025 0.0127
Plasmodium vivax unspecified product 0.0366 0.0607 0.3065
Echinococcus multilocularis Mitotic checkpoint protein PRCC, C terminal 0.0126 0.0192 0.0192
Loa Loa (eye worm) hypothetical protein 0.0017 0.0003 0.0008
Trichomonas vaginalis DNA helicase recq, putative 0.0032 0.003 0.0139
Onchocerca volvulus 0.1158 0.1975 1
Echinococcus granulosus tripartite motif containing protein 3 0.0031 0.0027 0.0027
Toxoplasma gondii centrin, putative 0.0045 0.0052 0.0264
Echinococcus multilocularis ATP dependent DNA helicase Q1 0.003 0.0025 0.0025
Onchocerca volvulus 0.0072 0.0098 0.0496
Brugia malayi Protein kinase domain containing protein 0.0032 0.003 0.0092
Echinococcus multilocularis cathepsin l cysteine peptidase 0.1158 0.1975 0.1975
Echinococcus granulosus neuropeptide Y receptor 0.0095 0.0137 0.0137
Plasmodium vivax SET domain protein, putative 0.0061 0.0079 0.0388
Giardia lamblia Cysteine protease 0.0255 0.0414 0.3221
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.1205 0.2057 1
Chlamydia trachomatis fructose-6-phosphate phosphotransferase 0.0029 0.0025 1
Brugia malayi calcium-binding protein 0.0045 0.0052 0.0163
Entamoeba histolytica cysteine protease, putative 0.0621 0.1047 0.53
Schistosoma mansoni 6-phosphofructokinase 0.0108 0.0161 0.0501
Plasmodium falciparum plasmepsin V 0.0145 0.0225 0.113
Loa Loa (eye worm) hypothetical protein 0.0095 0.0137 0.0427
Echinococcus multilocularis Mastin 0.0066 0.0089 0.0089
Echinococcus multilocularis rhodopsin orphan GPCR 0.0095 0.0137 0.0137
Trypanosoma brucei Calpain-like protein 2 0.0582 0.098 0.4761
Plasmodium falciparum serine repeat antigen 9 0.0255 0.0414 0.2087
Brugia malayi Copper type II ascorbate-dependent monooxygenase, N-terminal domain containing protein 0.0315 0.0519 0.1613
Onchocerca volvulus Cathepsin L homolog 0.0255 0.0414 0.2096
Leishmania major hypothetical protein, conserved,calpain-like cysteine peptidase, Clan CA, family C2 0.0206 0.033 0.1595
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0255 0.0414 0.1287
Trypanosoma cruzi cysteine peptidase, putative 0.1205 0.2057 0.6395
Echinococcus granulosus g protein coupled receptor 0.0095 0.0137 0.0137
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.1158 0.1975 1
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.1205 0.2057 1
Trypanosoma cruzi cysteine peptidase (N-terminal), putative 0.0621 0.1047 0.3255
Onchocerca volvulus Cathepsin L homolog 0.1158 0.1975 1
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0794 0.1347 0.6544
Plasmodium falciparum ATP-dependent 6-phosphofructokinase 0.0029 0.0025 0.0113
Echinococcus multilocularis atpase aaa+ type core atpase aaa type core 0.1683 0.2882 0.2882
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.0021 0.001 0.003
Mycobacterium tuberculosis Conserved protein 0.0072 0.0099 0.1256
Schistosoma mansoni neuronal calcium sensor 0.0045 0.0052 0.0162
Plasmodium vivax cysteine repeat modular protein 1, putative 0.0134 0.0206 0.1031
Loa Loa (eye worm) hypothetical protein 0.0021 0.001 0.0031
Loa Loa (eye worm) hypothetical protein 0.0045 0.0052 0.0163
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0457 0.0763 0.2374
Mycobacterium leprae conserved hypothetical protein 0.0072 0.0099 0.4832
Toxoplasma gondii centrin 0.0045 0.0052 0.0264
Trypanosoma brucei cysteine peptidase, Clan CA, family C2, putative 0.0261 0.0425 0.2059
Onchocerca volvulus 0.0095 0.0137 0.0696
Brugia malayi Chymotrypsin-like protease CTRL-1 precursor 0.0066 0.0089 0.0276
Schistosoma mansoni thyrotropin-releasing hormone receptor 0.0095 0.0137 0.0427
Echinococcus granulosus sarcoplasmic calcium binding protein 0.0045 0.0052 0.0052
Brugia malayi Cathepsin L-like precursor 0.0792 0.1342 0.4174
Onchocerca volvulus Protein ultraspiracle homolog 0.0021 0.001 0.005
Echinococcus multilocularis centrin 2 0.0045 0.0052 0.0052
Brugia malayi Matrix metalloprotease, N-terminal domain containing protein 0.0028 0.0023 0.007
Loa Loa (eye worm) trypsin family protein 0.0066 0.0089 0.0276
Loa Loa (eye worm) cytochrome P450 family protein 0.0035 0.0034 0.0107
Echinococcus multilocularis cytoplasmic intermediate filament protein 0.0027 0.002 0.002
Echinococcus multilocularis sarcoplasmic calcium binding protein 0.0045 0.0052 0.0052
Onchocerca volvulus 0.0056 0.007 0.0354
Trypanosoma brucei ATP-dependent 6-phosphofructokinase, glycosomal 0.0108 0.0161 0.0773
Entamoeba histolytica cysteine proteinase, putative 0.0621 0.1047 0.53
Schistosoma mansoni cpg binding protein 0.003 0.0025 0.0079
Plasmodium vivax vivapain-2 0.1158 0.1975 1
Toxoplasma gondii cathepsin CPC1 0.0255 0.0414 0.2095
Loa Loa (eye worm) gonadotropin-releasing hormone receptor 2 0.0095 0.0137 0.0427
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.0621 0.1047 0.3255
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0301 0.0494 0.1537
Echinococcus granulosus NADP dependent isocitrate dehydrogenase 0.0017 0.0003 0.0003
Onchocerca volvulus 0.0033 0.0031 0.0155
Schistosoma mansoni DNA polymerase eta 0.0063 0.0084 0.026
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.075 0.1271 0.6174
Plasmodium falciparum cysteine proteinase falcipain 1 0.0621 0.1047 0.5295
Onchocerca volvulus 0.0095 0.0137 0.0696
Giardia lamblia Cathepsin B-like cysteine proteinase 3 precursor 0.0255 0.0414 0.3221
Echinococcus multilocularis neuropeptide Y receptor 0.0095 0.0137 0.0137
Brugia malayi steroid hormone receptor 0.0021 0.001 0.0031
Onchocerca volvulus 0.0042 0.0047 0.0237
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0095 0.0137 0.0427
Brugia malayi G-protein-linked acetylcholine receptor protein 2, putative 0.0095 0.0137 0.0427
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0021 0.001 0.001
Echinococcus granulosus dna polymerase eta 0.0063 0.0084 0.0084
Schistosoma mansoni cercarial elastase (S01 family) 0.0066 0.0089 0.0276
Entamoeba histolytica calpain family cysteine protease, putative 0.0251 0.0407 0.2062
Schistosoma mansoni amine GPCR 0.0095 0.0137 0.0427
Brugia malayi Pre-SET motif family protein 0.042 0.0699 0.2173
Schistosoma mansoni transcription factor LCR-F1 0.0043 0.0049 0.0152
Trypanosoma cruzi PAB1-binding protein , putative 0.0053 0.0065 0.0202
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.1205 0.2057 1
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0095 0.0137 0.0427
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0017 0.0003 0.0003
Echinococcus multilocularis glycoprotein Antigen 5 0.0066 0.0089 0.0089
Echinococcus granulosus 6 phosphofructokinase 0.0108 0.0161 0.0161
Plasmodium falciparum dipeptidyl aminopeptidase 1 0.0255 0.0414 0.2087
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0095 0.0137 0.0427
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0052 0.0065 0.0201
Brugia malayi hypothetical protein 0.0095 0.0137 0.0427
Leishmania major hypothetical protein, conserved 0.0206 0.033 0.1595
Loa Loa (eye worm) hypothetical protein 0.0095 0.0137 0.0427
Onchocerca volvulus 0.0095 0.0137 0.0696
Entamoeba histolytica calcium-binding protein, putative 0.0045 0.0052 0.0264
Toxoplasma gondii aspartyl proteinase (eimepsin), putative 0.0615 0.1037 0.5248
Echinococcus granulosus FTZ F1 alpha 0.0021 0.001 0.001
Schistosoma mansoni hypothetical protein 0.0348 0.0576 0.179
Brugia malayi chromobox protein homolog 3 0.0038 0.0039 0.0123
Echinococcus granulosus ecdysone induced protein 78C 0.0021 0.001 0.001
Echinococcus granulosus transmembrane protease serine 3 0.0066 0.0089 0.0089
Schistosoma mansoni biogenic amine receptor 0.0095 0.0137 0.0427
Onchocerca volvulus 0.0042 0.0047 0.0237
Brugia malayi PAN domain containing protein 0.0042 0.0047 0.0145
Trypanosoma brucei DNA polymerase IV, putative 0.0038 0.004 0.0182
Brugia malayi aspartic protease BmAsp-1, identical 0.0145 0.0225 0.0701
Plasmodium falciparum plasmepsin I 0.0615 0.1037 0.5243
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0255 0.0414 0.1287
Echinococcus multilocularis matrix metallopeptidase 7 (M10 family) 0.0084 0.0119 0.0119
Echinococcus multilocularis nervana 2 0.002 0.0008 0.0008
Schistosoma mansoni reticulocalbin 0.0045 0.0052 0.0162
Loa Loa (eye worm) hypothetical protein 0.0255 0.0414 0.1287
Leishmania major trypanothione reductase 0.0047 0.0056 0.026
Mycobacterium ulcerans exodeoxyribonuclease III protein XthA 0.0038 0.0039 0.2307
Brugia malayi hypothetical protein 0.0145 0.0225 0.0701
Toxoplasma gondii kringle domain-containing protein 0.0134 0.0206 0.1041
Leishmania major kinesin, putative 0.0238 0.0386 0.1867
Schistosoma mansoni hypothetical protein 0.0017 0.0003 0.0008
Loa Loa (eye worm) RNA binding protein 0.0067 0.0089 0.0277
Schistosoma mansoni opsin-like receptor 0.0095 0.0137 0.0427
Toxoplasma gondii calcium binding egf domain-containing protein 0.0026 0.0019 0.0097
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0066 0.0089 0.0276
Entamoeba histolytica EF-hand calcium-binding domain containing protein 0.0045 0.0052 0.0264
Loa Loa (eye worm) hypothetical protein 0.0095 0.0137 0.0427
Plasmodium vivax hypothetical protein, conserved 0.0072 0.0099 0.0491
Brugia malayi Cytochrome P450 family protein 0.0035 0.0034 0.0107
Echinococcus multilocularis calpain family protein 1, d 0.0723 0.1223 0.1223
Schistosoma mansoni thyroid hormone receptor 0.0147 0.0227 0.0707
Brugia malayi gonadotropin-releasing hormone receptor 2 0.0095 0.0137 0.0427
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.075 0.1271 0.6174
Toxoplasma gondii hypothetical protein 0.0042 0.0047 0.0236
Echinococcus granulosus cathepsin l1 0.1158 0.1975 0.1975
Giardia lamblia Cathepsin B precursor 0.0756 0.1281 1
Echinococcus granulosus calumenin 0.0046 0.0054 0.0054
Echinococcus multilocularis bloom syndrome protein 0.0042 0.0047 0.0047
Trichomonas vaginalis D-aminoacylase, putative 0.0072 0.0099 0.0491
Trichomonas vaginalis calmodulin, putative 0.0045 0.0052 0.0253
Giardia lamblia Cathepsin B precursor 0.0756 0.1281 1
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0794 0.1347 0.4187
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0794 0.1347 0.6544
Trypanosoma brucei PAB1-binding protein , putative 0.0053 0.0065 0.0305
Schistosoma mansoni DNA helicase recq1 0.003 0.0025 0.0078
Trypanosoma brucei hypothetical protein, conserved 0.0045 0.0052 0.0243
Trichomonas vaginalis calmodulin, putative 0.0045 0.0052 0.0253
Trypanosoma cruzi hypothetical protein, conserved 0.0334 0.0551 0.1712
Plasmodium vivax glutathione reductase, putative 0.0047 0.0056 0.0271
Trypanosoma brucei isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0017 0.0003 0.0002
Brugia malayi PAN domain containing protein 0.0042 0.0047 0.0145
Trypanosoma cruzi kinesin, putative 0.0238 0.0386 0.12
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0095 0.0137 0.0137
Plasmodium falciparum thioredoxin reductase 0.0047 0.0056 0.0271
Mycobacterium tuberculosis Probable conserved lipoprotein 0.0072 0.0099 0.1256
Leishmania major cathepsin L-like protease 0.1158 0.1975 0.9604
Trichomonas vaginalis conserved hypothetical protein 0.0251 0.0407 0.2053
Loa Loa (eye worm) follicle stimulating hormone receptor 0.0095 0.0137 0.0427
Echinococcus granulosus enteropeptidase 0.0066 0.0089 0.0089
Loa Loa (eye worm) B-box zinc finger family protein 0.0031 0.0027 0.0084
Loa Loa (eye worm) cytochrome P450 family protein 0.0033 0.0031 0.0096
Brugia malayi putative neuropeptide receptor 0.0095 0.0137 0.0427
Echinococcus multilocularis neuropeptides capa receptor 0.0095 0.0137 0.0137
Echinococcus granulosus GPCR family 2 0.0017 0.0003 0.0003
Brugia malayi nuclear hormone receptor 0.0021 0.001 0.0031
Leishmania major calpain, putative,cysteine peptidase, Clan CA, family C2, putative 0.0489 0.0819 0.3977
Echinococcus granulosus Mitotic checkpoint protein PRCC C terminal 0.0126 0.0192 0.0192
Echinococcus multilocularis allatostatin A receptor 0.0095 0.0137 0.0137
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.0021 0.001 0.0031
Entamoeba histolytica protein kinase, putative 0.0032 0.003 0.0149
Echinococcus multilocularis lamin dm0 0.0056 0.007 0.007
Trichomonas vaginalis 6-phosphofructokinase, putative 0.0029 0.0025 0.0113
Brugia malayi ERG2 and Sigma1 receptor like protein 0.0359 0.0594 0.1847
Entamoeba histolytica papain family cysteine protease domain containing protein 0.0255 0.0414 0.2095
Trypanosoma brucei Small kinetoplastid calpain-related protein 1-5 0.0206 0.033 0.1595
Trypanosoma cruzi cysteine peptidase, putative 0.0366 0.0607 0.1887
Plasmodium vivax AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0038 0.0039 0.0186
Onchocerca volvulus 0.0042 0.0047 0.0237
Echinococcus multilocularis alpha 1A adrenergic receptor 0.0095 0.0137 0.0137
Loa Loa (eye worm) hypothetical protein 0.0095 0.0137 0.0427
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0021 0.001 0.0031
Mycobacterium ulcerans DNA polymerase IV 0.0038 0.004 0.235
Brugia malayi hypothetical protein 0.0095 0.0137 0.0427
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.1158 0.1975 1
Echinococcus granulosus bloom syndrome protein 0.0042 0.0047 0.0047
Loa Loa (eye worm) hypothetical protein 0.0095 0.0137 0.0427
Schistosoma mansoni ap endonuclease 0.0038 0.0039 0.0121
Loa Loa (eye worm) hypothetical protein 0.0031 0.0027 0.0084
Echinococcus multilocularis neurocalcin 0.0045 0.0052 0.0052
Trypanosoma brucei DNA polymerase kappa, putative 0.0038 0.004 0.0182
Echinococcus multilocularis neuropeptide Y receptor 0.0095 0.0137 0.0137
Trichomonas vaginalis AGC family protein kinase 0.0032 0.003 0.0138
Trichomonas vaginalis conserved hypothetical protein 0.0027 0.002 0.0091
Echinococcus granulosus microtubule associated protein 2 0.0726 0.1228 0.1228
Brugia malayi Matrixin family protein 0.0023 0.0014 0.0043
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.0021 0.001 0.003
Loa Loa (eye worm) hypothetical protein 0.1169 0.1994 0.6202
Loa Loa (eye worm) calpain family protein 1 0.0962 0.1635 0.5085
Leishmania major calmodulin-like protein 0.0045 0.0052 0.0243
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative 0.0038 0.0039 0.0178
Plasmodium falciparum ADP-dependent DNA helicase RecQ 0.004 0.0042 0.0203
Echinococcus multilocularis G-protein coupled receptor, putative 0.0095 0.0137 0.0137
Brugia malayi hypothetical protein 0.0095 0.0137 0.0427
Giardia lamblia Cathepsin L precursor 0.0255 0.0414 0.3221
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.0021 0.001 0.0031
Schistosoma mansoni subfamily C1A unassigned peptidase (C01 family) 0.0255 0.0414 0.1287
Echinococcus multilocularis cathepsin L cysteine protease 0.1158 0.1975 0.1975
Loa Loa (eye worm) hypothetical protein 0.0095 0.0137 0.0427
Echinococcus multilocularis brain tumor protein 0.0031 0.0027 0.0027
Toxoplasma gondii isocitrate dehydrogenase 0.0017 0.0003 0.0013
Echinococcus multilocularis rhodopsin orphan GPCR 0.0095 0.0137 0.0137
Echinococcus multilocularis EF hand domain containing family member A2 0.0045 0.0052 0.0052
Entamoeba histolytica cysteine proteinase, putative 0.0792 0.1342 0.6795
Trypanosoma brucei trypanothione reductase 0.0047 0.0056 0.026
Toxoplasma gondii PAN domain-containing protein 0.0042 0.0047 0.0236
Plasmodium falciparum calpain 0.0251 0.0407 0.2053
Schistosoma mansoni cercarial elastase (S01 family) 0.0066 0.0089 0.0276
Giardia lamblia Hypothetical protein 0.0103 0.0152 0.1168
Brugia malayi Cytochrome P450 family protein 0.0033 0.0031 0.0096
Loa Loa (eye worm) NCL-1 protein 0.0031 0.0027 0.0084
Loa Loa (eye worm) hypothetical protein 0.0042 0.0047 0.0145
Brugia malayi photoreceptor-specific nuclear receptor 0.0021 0.001 0.0031
Echinococcus multilocularis family C2 unassigned peptidase (C02 family) 0.1007 0.1714 0.1714
Giardia lamblia Cathepsin B precursor 0.0255 0.0414 0.3221
Loa Loa (eye worm) 6-phosphofructokinase 0.0108 0.0161 0.0501
Loa Loa (eye worm) PAN domain-containing protein 0.0042 0.0047 0.0145
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0188 0.0298 0.0298
Echinococcus granulosus alpha 1A adrenergic receptor 0.0095 0.0137 0.0137
Trypanosoma brucei kinesin, putative 0.0238 0.0386 0.1867
Echinococcus multilocularis tripartite motif containing protein 3 0.0031 0.0027 0.0027
Toxoplasma gondii 6-phosphofructokinase 0.0029 0.0025 0.0124
Leishmania major hypothetical protein, conserved 0.0206 0.033 0.1595
Echinococcus multilocularis serotonin receptor 0.0095 0.0137 0.0137
Echinococcus multilocularis terminal deoxycytidyl transferase rev1 0.0038 0.004 0.004
Giardia lamblia Cathepsin B precursor 0.0255 0.0414 0.3221
Toxoplasma gondii cathepsin B 0.0756 0.1281 0.6483
Loa Loa (eye worm) hypothetical protein 0.0023 0.0014 0.0043
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0016 0.0002 0.0007
Schistosoma mansoni cathepsin F (C01 family) 0.0792 0.1342 0.4174
Loa Loa (eye worm) matrix metalloproteinase 0.0023 0.0014 0.0043
Trichomonas vaginalis calcium binding protein, putative 0.0045 0.0052 0.0253
Trypanosoma brucei calmodulin, putative 0.0045 0.0052 0.0243
Brugia malayi intermediate filament protein 0.0056 0.007 0.0218
Plasmodium vivax isocitrate dehydrogenase [NADP], mitochondrial, putative 0.0017 0.0003 0.0002
Toxoplasma gondii calcium-dependent protein kinase 0.0046 0.0054 0.0274
Echinococcus multilocularis neuropeptides capa receptor 0.0095 0.0137 0.0137
Loa Loa (eye worm) matrixin family protein 0.0056 0.007 0.0219
Echinococcus granulosus Mastin 0.0066 0.0089 0.0089
Leishmania major calpain protease-like protein 0.0251 0.0407 0.1972
Mycobacterium tuberculosis Probable hydrolase 0.0072 0.0099 0.1256
Echinococcus granulosus EF hand domain containing family member A2 0.0046 0.0054 0.0054
Echinococcus granulosus serotonin receptor 0.0095 0.0137 0.0137
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0188 0.0298 0.0927
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0018 0.0005 0.0012
Echinococcus granulosus 7TM GPCR rhodopsin 0.0095 0.0137 0.0137
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0021 0.001 0.0031
Brugia malayi hypothetical protein 0.0034 0.0033 0.0102
Brugia malayi Dopamine receptor 0.0095 0.0137 0.0427
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0255 0.0414 0.1287
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.0056 0.007 0.0218
Onchocerca volvulus 0.0095 0.0137 0.0696
Mycobacterium tuberculosis NAD(P)H quinone reductase LpdA 0.012 0.0181 0.2318
Trypanosoma brucei DNA polymerase IV, putative 0.0038 0.004 0.0182
Echinococcus multilocularis lamin 0.0056 0.007 0.007
Trichomonas vaginalis Clan CA, family C2, calpain-like cysteine peptidase 0.0251 0.0407 0.2053
Leishmania major ATP-dependent phosphofructokinase 0.0108 0.0161 0.0773
Echinococcus granulosus peptide allatostatin:somatostatin 0.0095 0.0137 0.0137
Schistosoma mansoni subfamily C1A non-peptidase homologue (C01 family) 0.0255 0.0414 0.1287
Echinococcus multilocularis g-protein coupled receptor 0.0095 0.0137 0.0137
Schistosoma mansoni cpg binding protein 0.0031 0.0028 0.0088
Leishmania major cathepsin L-like protease 0.1158 0.1975 0.9604
Trypanosoma cruzi small myristoylated protein 1-1 0.0355 0.0588 0.1829
Brugia malayi Low-density lipoprotein receptor repeat class B containing protein 0.0026 0.0019 0.006
Mycobacterium tuberculosis Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) 0.0038 0.0039 0.0475
Entamoeba histolytica cysteine proteinase, putative 0.0621 0.1047 0.53
Loa Loa (eye worm) hypothetical protein 0.0095 0.0137 0.0427
Trypanosoma brucei prefoldin subunit, putative 0.0103 0.0152 0.0727
Plasmodium vivax vivapain-3 0.0621 0.1047 0.5295
Echinococcus granulosus nuclear factor of activated T cells 5 0.0074 0.0101 0.0101
Brugia malayi calpain 7 0.0489 0.0819 0.2548
Giardia lamblia Hypothetical protein 0.0031 0.0027 0.0192
Loa Loa (eye worm) hypothetical protein 0.0095 0.0137 0.0427
Echinococcus granulosus pyroglutamylated rfamide peptide receptor 0.0095 0.0137 0.0137
Entamoeba histolytica cysteine protease, putative 0.0621 0.1047 0.53
Trypanosoma brucei caltractin, putative 0.0053 0.0066 0.0311
Brugia malayi hypothetical protein 0.0066 0.0089 0.0276
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0066 0.0089 0.0276
Loa Loa (eye worm) hypothetical protein 0.0095 0.0137 0.0427
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0095 0.0137 0.0137
Leishmania major apurinic/apyrimidinic endonuclease-redox protein 0.0038 0.0039 0.0178
Plasmodium vivax 6-phosphofructokinase, putative 0.0029 0.0025 0.0113
Brugia malayi Kringle domain containing protein 0.0134 0.0206 0.064
Loa Loa (eye worm) cathepsin B 0.0756 0.1281 0.3982
Loa Loa (eye worm) CYP4Cod1 0.0033 0.0031 0.0096
Trypanosoma cruzi cysteine peptidase, putative 0.0621 0.1047 0.3255
Trypanosoma brucei DNA polymerase kappa, putative 0.0038 0.004 0.0182
Brugia malayi Trypsin-like protease protein 5 0.0066 0.0089 0.0276
Brugia malayi Thioredoxin reductase 0.0047 0.0056 0.0173
Plasmodium vivax dipeptidyl aminopeptidase 3, putative 0.0255 0.0414 0.2087
Loa Loa (eye worm) hypothetical protein 0.0183 0.0291 0.0905
Toxoplasma gondii PAN domain-containing protein 0.0042 0.0047 0.0236
Schistosoma mansoni calmodulin 0.0045 0.0052 0.0162
Schistosoma mansoni hypothetical protein 0.0134 0.0206 0.0639
Plasmodium falciparum glutathione reductase 0.0047 0.0056 0.0271
Echinococcus multilocularis neuropeptide FF receptor 2 0.0095 0.0137 0.0137
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.0021 0.001 0.0031
Onchocerca volvulus 0.0045 0.0052 0.0265
Loa Loa (eye worm) papain family cysteine protease containing protein 0.1158 0.1975 0.6142
Onchocerca volvulus 0.0472 0.079 0.4
Echinococcus granulosus programmed cell death protein 0.0053 0.0066 0.0066
Onchocerca volvulus 0.0134 0.0206 0.1042
Plasmodium falciparum serine repeat antigen 4 0.0255 0.0414 0.2087
Giardia lamblia Pyrophosphate-fructose 6-phosphate 1-phosphotransferase alpha subunit 0.0029 0.0025 0.0174
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0792 0.1342 0.6792
Schistosoma mansoni hypothetical protein 0.0103 0.0152 0.0471
Trypanosoma brucei small myristoylated protein 1-2 0.0355 0.0588 0.2852
Trypanosoma cruzi hypothetical protein, conserved 0.0334 0.0551 0.1712
Schistosoma mansoni Sarcoplasmic calcium-binding protein (SCP). 0.0045 0.0052 0.0162
Loa Loa (eye worm) transcription factor SMAD2 0.0144 0.0223 0.0694
Loa Loa (eye worm) matrixin family protein 0.0051 0.0062 0.0194
Loa Loa (eye worm) hypothetical protein 0.0366 0.0607 0.1888
Onchocerca volvulus 0.0066 0.0089 0.045
Entamoeba histolytica cysteine proteinase, putative 0.1158 0.1975 1
Echinococcus multilocularis peptidyl glycine alpha amidating monooxygenase 0.1169 0.1994 0.1994
Toxoplasma gondii microneme protein MIC17B 0.0042 0.0047 0.0236
Brugia malayi Hypothetical RING finger protein F54G8.4 in chromosome III 0.0031 0.0027 0.0084
Schistosoma mansoni peptide (allatostatin)-like receptor 0.0095 0.0137 0.0427
Trichomonas vaginalis calcineurin B subunit, putative 0.0046 0.0054 0.0261
Loa Loa (eye worm) hypothetical protein 0.0066 0.0089 0.0276
Schistosoma mansoni lamin 0.0056 0.007 0.0217
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.0021 0.001 0.001
Loa Loa (eye worm) calpain 5 0.0238 0.0386 0.12
Trypanosoma brucei conserved protein 0.0215 0.0345 0.1669
Echinococcus granulosus tm gpcr rhodopsin 0.0095 0.0137 0.0137
Loa Loa (eye worm) unidentified vitellogenin-linked transcript protein 6 0.0095 0.0137 0.0427
Entamoeba histolytica deoxycytidyl transferase, putative 0.0038 0.004 0.02
Leishmania major phospholipase c-like protein 0.0045 0.0052 0.0243
Echinococcus granulosus rhodopsin orphan GPCR 0.0095 0.0137 0.0137
Echinococcus multilocularis fmrfamide receptor 0.0095 0.0137 0.0137
Loa Loa (eye worm) hypothetical protein 0.0031 0.0027 0.0084
Brugia malayi ImpB/MucB/SamB family protein 0.0063 0.0084 0.026
Mycobacterium tuberculosis Probable lipase LipE 0.0072 0.0099 0.1256
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.0038 0.0039 0.0039
Schistosoma mansoni cercarial elastase (S01 family) 0.0066 0.0089 0.0276
Loa Loa (eye worm) hypothetical protein 0.0026 0.0019 0.006
Plasmodium falciparum serine repeat antigen 6 0.0255 0.0414 0.2087
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.1876 0.3216 1
Echinococcus granulosus cytoplasmic intermediate filament protein 0.0027 0.002 0.002
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0061 0.0079 0.0245
Echinococcus granulosus muscleblind protein 0.0154 0.0241 0.0241
Trypanosoma cruzi calmodulin, putative 0.0045 0.0052 0.0162
Echinococcus granulosus sodium channel protein 0.0041 0.0044 0.0044
Giardia lamblia Cathepsin L precursor 0.0255 0.0414 0.3221
Loa Loa (eye worm) G-protein coupled receptor 0.0095 0.0137 0.0427
Echinococcus granulosus neuropeptide receptor 0.0095 0.0137 0.0137
Brugia malayi cathepsin L-like cysteine proteinase, identical 0.0366 0.0607 0.1888
Brugia malayi cathepsin L-like precursor 0.0792 0.1342 0.4174
Trichomonas vaginalis AGC family protein kinase 0.0032 0.003 0.0138
Echinococcus granulosus Peptidase S1 S6 chymotrypsin Hap 0.0066 0.0089 0.0089
Echinococcus multilocularis tar DNA binding protein 0.0067 0.0089 0.0089
Entamoeba histolytica cysteine protease, putative 0.0621 0.1047 0.53
Treponema pallidum diphosphate--fructose-6-phosphate 1-phosphotransferase 0.0029 0.0025 0.1518
Trypanosoma cruzi CAMK/CAMKL family protein kinase, putative 0.0046 0.0053 0.0163
Trypanosoma cruzi hypothetical protein, conserved 0.0072 0.0099 0.0308
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.1876 0.3216 1
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0095 0.0137 0.0137
Trypanosoma cruzi Protein kinase B 0.0022 0.0012 0.0037
Loa Loa (eye worm) hypothetical protein 0.1158 0.1975 0.6142
Brugia malayi Bloom's syndrome protein homolog 0.0042 0.0047 0.0146
Plasmodium vivax serine-repeat antigen (SERA) 0.0255 0.0414 0.2087
Loa Loa (eye worm) hypothetical protein 0.0042 0.0047 0.0145
Brugia malayi TAR-binding protein 0.0067 0.0089 0.0277
Loa Loa (eye worm) heterochromatin protein 1 0.0067 0.0091 0.0282
Plasmodium falciparum dipeptidyl aminopeptidase 3 0.0255 0.0414 0.2087
Leishmania major C-8 sterol isomerase-like protein 0.0359 0.0594 0.288
Brugia malayi Dopamine receptor protein 2 0.0095 0.0137 0.0427
Plasmodium falciparum dipeptidyl aminopeptidase 2 0.0255 0.0414 0.2087
Onchocerca volvulus 0.0042 0.0047 0.0237
Mycobacterium leprae DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE 0.012 0.0181 1
Schistosoma mansoni brat protein 0.0031 0.0027 0.0083
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0017 0.0003 0.0003
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.1158 0.1975 1
Brugia malayi cathepsin F-like cysteine proteinase 0.0255 0.0414 0.1287
Echinococcus granulosus cathepsin b 0.1876 0.3216 0.3216
Giardia lamblia Endonuclease/Exonuclease/phosphatase 0.0038 0.0039 0.0287
Trypanosoma cruzi hypothetical protein, conserved 0.0206 0.033 0.1026
Schistosoma mansoni subfamily M12A unassigned peptidase (M12 family) 0.0026 0.0019 0.006
Brugia malayi Cathepsin L-like precursor 0.0366 0.0607 0.1888
Mycobacterium tuberculosis Conserved hypothetical protein 0.0038 0.004 0.0484
Toxoplasma gondii ImpB/MucB/SamB family protein 0.0037 0.0038 0.0194
Brugia malayi exodeoxyribonuclease III family protein 0.0038 0.0039 0.0121
Echinococcus multilocularis cpg binding protein 0.0031 0.0028 0.0028
Echinococcus multilocularis cysteine protease 0.1158 0.1975 0.1975
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.1158 0.1975 1
Loa Loa (eye worm) PAN domain-containing protein 0.0042 0.0047 0.0145
Trypanosoma brucei cysteine peptidase, Clan CA, family C2, putative 0.0439 0.0733 0.3555
Entamoeba histolytica hypothetical protein 0.0255 0.0414 0.2095

Activities

Activity type Activity value Assay description Source Reference
Potency (functional) 3.9811 uM PubChem BioAssay. qHTS for Agonist of gsp, the Etiologic Mutation Responsible for Fibrous Dysplasia/McCune-Albright Syndrome: qHTS. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) 6.5131 uM PUBCHEM_BIOASSAY: Nrf2 qHTS screen for inhibitors. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID493153, AID493163, AID504648] ChEMBL. No reference
Potency (functional) 11.2202 uM PUBCHEM_BIOASSAY: qHTS for Inhibitors of TGF-b. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID588856, AID588860] ChEMBL. No reference
Potency (functional) 89.1251 uM PUBCHEM_BIOASSAY: qHTS Assay for Inhibitors of Histone Lysine Methyltransferase G9a. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID504404] ChEMBL. No reference

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

Bibliographic References

No literature references available for this target.

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