Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Loa Loa (eye worm) | hypothetical protein | 0.0095 | 0.1427 | 0.1427 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0046 | 0.0433 | 0.0606 |
Echinococcus granulosus | nuclear receptor subfamily 1 group D | 0.0123 | 0.1975 | 0.2765 |
Loa Loa (eye worm) | hypothetical protein | 0.0095 | 0.1427 | 0.1427 |
Loa Loa (eye worm) | hypothetical protein | 0.0036 | 0.0242 | 0.0242 |
Brugia malayi | Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative | 0.0036 | 0.0242 | 0.0242 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0136 | 0.2246 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0095 | 0.1427 | 0.1427 |
Entamoeba histolytica | cysteine proteinase, putative | 0.0036 | 0.0236 | 0.9324 |
Echinococcus multilocularis | cathepsin l cysteine peptidase | 0.0036 | 0.0236 | 0.0459 |
Loa Loa (eye worm) | beta-lactamase | 0.0036 | 0.0242 | 0.0242 |
Schistosoma mansoni | nuclear hormone receptor | 0.0218 | 0.3881 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0036 | 0.0242 | 0.0242 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L or K-like cysteine peptidase | 0.0036 | 0.0236 | 0.9324 |
Loa Loa (eye worm) | beta-LACTamase domain containing family member | 0.0036 | 0.0242 | 0.0242 |
Schistosoma mansoni | nuclear receptor | 0.0095 | 0.1427 | 0.3677 |
Loa Loa (eye worm) | intermediate filament protein | 0.0027 | 0.0061 | 0.0061 |
Onchocerca volvulus | 0.0036 | 0.0242 | 0.0242 | |
Schistosoma mansoni | nuclear hormone receptor nor-1/nor-2 | 0.0218 | 0.3881 | 1 |
Echinococcus granulosus | FTZ F1 alpha | 0.0218 | 0.3881 | 0.5434 |
Loa Loa (eye worm) | hypothetical protein | 0.0095 | 0.1427 | 0.1427 |
Brugia malayi | Nuclear hormone receptor family member nhr-19 | 0.0218 | 0.3881 | 0.3881 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0036 | 0.0236 | 0.9324 |
Loa Loa (eye worm) | GTP-binding regulatory protein Gs alpha-S chain | 0.0046 | 0.0433 | 0.0433 |
Schistosoma mansoni | nuclear hormone receptor superfamily protein-related | 0.0095 | 0.1427 | 0.3677 |
Loa Loa (eye worm) | hypothetical protein | 0.0123 | 0.1975 | 0.1975 |
Brugia malayi | nuclear receptor RXR | 0.0123 | 0.1975 | 0.1975 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0036 | 0.0236 | 0.9324 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0136 | 0.2246 | 1 |
Leishmania major | cathepsin L-like protease | 0.0136 | 0.2246 | 1 |
Trypanosoma cruzi | major cysteine proteinase, putative | 0.0107 | 0.1663 | 0.7098 |
Trichomonas vaginalis | penicillin-binding protein, putative | 0.0036 | 0.0242 | 0.9553 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0036 | 0.0236 | 0.9324 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0036 | 0.0236 | 0.9324 |
Brugia malayi | photoreceptor-specific nuclear receptor | 0.0218 | 0.3881 | 0.3881 |
Mycobacterium tuberculosis | Probable esterase/lipase LipP | 0.0036 | 0.0242 | 0.0166 |
Echinococcus granulosus | FTZ F1 nuclear receptor protein | 0.0218 | 0.3881 | 0.5434 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0036 | 0.0236 | 0.9324 |
Brugia malayi | nuclear receptor RXR | 0.0095 | 0.1427 | 0.1427 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0136 | 0.2246 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0036 | 0.0236 | 0.9324 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0046 | 0.0433 | 0.1115 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0136 | 0.2246 | 1 |
Onchocerca volvulus | 0.0027 | 0.0061 | 0.0061 | |
Echinococcus granulosus | geminin | 0.0168 | 0.2875 | 0.4026 |
Loa Loa (eye worm) | hypothetical protein | 0.0027 | 0.0061 | 0.0061 |
Brugia malayi | hypothetical protein | 0.0123 | 0.1975 | 0.1975 |
Schistosoma mansoni | Tr4/Tr2 (homologue) | 0.0218 | 0.3881 | 1 |
Trichomonas vaginalis | D-aminoacylase, putative | 0.0036 | 0.0242 | 0.9553 |
Trichomonas vaginalis | esterase, putative | 0.0036 | 0.0242 | 0.9553 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.0136 | 0.2246 | 1 |
Onchocerca volvulus | Protein ultraspiracle homolog | 0.0218 | 0.3881 | 0.3881 |
Schistosoma mansoni | retinoid-x-receptor (RXR) | 0.0123 | 0.1975 | 0.5089 |
Toxoplasma gondii | inositol(myo)-1(or 4)-monophosphatase 2, putative | 0.0037 | 0.0254 | 1 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0046 | 0.0433 | 0.0606 |
Loa Loa (eye worm) | nuclear hormone receptor | 0.0095 | 0.1427 | 0.1427 |
Echinococcus multilocularis | thyroid hormone receptor alpha | 0.0218 | 0.3881 | 1 |
Loa Loa (eye worm) | ctsf protein | 0.0036 | 0.0236 | 0.0236 |
Trichomonas vaginalis | inositol monophosphatase, putative | 0.0037 | 0.0254 | 1 |
Onchocerca volvulus | Bile acid receptor homolog | 0.0524 | 1 | 1 |
Onchocerca volvulus | 0.0027 | 0.0061 | 0.0061 | |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0036 | 0.0236 | 0.9324 |
Schistosoma mansoni | lamin | 0.0027 | 0.0061 | 0.0158 |
Trypanosoma cruzi | myo-inositol-1(or 4)-monophosphatase 1, putative | 0.0037 | 0.0254 | 0.0085 |
Schistosoma mansoni | retinoid-x-receptor (RXR) | 0.0218 | 0.3881 | 1 |
Loa Loa (eye worm) | nuclear receptor nhr-7B | 0.0095 | 0.1427 | 0.1427 |
Onchocerca volvulus | 0.0095 | 0.1427 | 0.1427 | |
Brugia malayi | hypothetical protein | 0.0095 | 0.1427 | 0.1427 |
Echinococcus multilocularis | FTZ F1 alpha | 0.0218 | 0.3881 | 1 |
Onchocerca volvulus | Nuclear receptor subfamily 6 group A member 1 homolog | 0.0095 | 0.1427 | 0.1427 |
Mycobacterium tuberculosis | Conserved protein | 0.0036 | 0.0242 | 0.0166 |
Loa Loa (eye worm) | hypothetical protein | 0.0095 | 0.1427 | 0.1427 |
Loa Loa (eye worm) | intermediate filament tail domain-containing protein | 0.0027 | 0.0061 | 0.0061 |
Echinococcus multilocularis | retinoic acid receptor rxr beta a retinoic acid receptor rxr alpha a retinoic acid receptor rxr alpha | 0.0095 | 0.1427 | 0.3575 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0136 | 0.2246 | 1 |
Brugia malayi | Cathepsin L-like precursor | 0.0036 | 0.0236 | 0.0236 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0136 | 0.2246 | 1 |
Leishmania major | hypothetical protein, conserved | 0.0036 | 0.0242 | 0.0029 |
Leishmania major | cathepsin L-like protease | 0.0136 | 0.2246 | 1 |
Schistosoma mansoni | ecdysone-induced protein 78c (dr-78) | 0.0123 | 0.1975 | 0.5089 |
Trichomonas vaginalis | D-aminoacylase, putative | 0.0036 | 0.0242 | 0.9553 |
Brugia malayi | beta-lactamase family protein | 0.0036 | 0.0242 | 0.0242 |
Brugia malayi | tailless protein | 0.0095 | 0.1427 | 0.1427 |
Trypanosoma brucei | inositol-1(or 4)-monophosphatase 1, putative | 0.0037 | 0.0254 | 0.0057 |
Echinococcus granulosus | nuclear receptor 2DBD gamma | 0.0218 | 0.3881 | 0.5434 |
Schistosoma mansoni | hypothetical protein | 0.0168 | 0.2875 | 0.7409 |
Schistosoma mansoni | family S12 unassigned peptidase (S12 family) | 0.0036 | 0.0242 | 0.0624 |
Loa Loa (eye worm) | nuclear hormone receptor-like 1 | 0.0123 | 0.1975 | 0.1975 |
Brugia malayi | nuclear receptor NHR-88 | 0.0218 | 0.3881 | 0.3881 |
Loa Loa (eye worm) | nuclear receptor NHR-67 | 0.0095 | 0.1427 | 0.1427 |
Trypanosoma cruzi | myo-inositol-1(or 4)-monophosphatase 1, putative | 0.0037 | 0.0254 | 0.0085 |
Echinococcus multilocularis | nuclear receptor 2DBD gamma | 0.0218 | 0.3881 | 1 |
Brugia malayi | Nuclear hormone receptor family member nhr-3 | 0.0218 | 0.3881 | 0.3881 |
Mycobacterium tuberculosis | Conserved protein | 0.0036 | 0.0242 | 0.0166 |
Echinococcus multilocularis | cysteine protease | 0.0036 | 0.0236 | 0.0459 |
Loa Loa (eye worm) | hypothetical protein | 0.0036 | 0.0242 | 0.0242 |
Echinococcus multilocularis | nuclear receptor 2DBD gamma | 0.0218 | 0.3881 | 1 |
Onchocerca volvulus | 0.0036 | 0.0242 | 0.0242 | |
Loa Loa (eye worm) | hypothetical protein | 0.0095 | 0.1427 | 0.1427 |
Brugia malayi | Nuclear hormone receptor family member nhr-25 | 0.0218 | 0.3881 | 0.3881 |
Brugia malayi | conserved hypotetical protein | 0.0095 | 0.1427 | 0.1427 |
Brugia malayi | Steroid receptor seven-up type 2 | 0.0218 | 0.3881 | 0.3881 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0136 | 0.2246 | 1 |
Mycobacterium tuberculosis | Conserved protein | 0.0036 | 0.0242 | 0.0166 |
Onchocerca volvulus | Nuclear receptor subfamily 6 group A member 1 homolog | 0.0095 | 0.1427 | 0.1427 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0036 | 0.0242 | 0.0029 |
Echinococcus multilocularis | nuclear receptor subfamily 1 group D | 0.0123 | 0.1975 | 0.5011 |
Schistosoma mansoni | family S12 unassigned peptidase (S12 family) | 0.0036 | 0.0242 | 0.0624 |
Plasmodium falciparum | cysteine proteinase falcipain 2a | 0.0036 | 0.0236 | 0.5 |
Brugia malayi | Nuclear hormone receptor family member nhr-31 | 0.0218 | 0.3881 | 0.3881 |
Schistosoma mansoni | thyroid hormone receptor | 0.0218 | 0.3881 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L or K-like cysteine peptidase | 0.0036 | 0.0236 | 0.9324 |
Brugia malayi | Nuclear hormone receptor family member nhr-14 | 0.0218 | 0.3881 | 0.3881 |
Echinococcus multilocularis | nuclear receptor 2DBD gamma | 0.0095 | 0.1427 | 0.3575 |
Echinococcus multilocularis | hepatocyte nuclear factor 4 alpha | 0.0218 | 0.3881 | 1 |
Echinococcus granulosus | COUP TF:Svp nuclear hormone receptor | 0.0218 | 0.3881 | 0.5434 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0036 | 0.0236 | 0.9324 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0036 | 0.0236 | 0.9324 |
Echinococcus granulosus | ecdysone induced protein 78C | 0.0218 | 0.3881 | 0.5434 |
Leishmania major | cathepsin L-like protease | 0.0136 | 0.2246 | 1 |
Schistosoma mansoni | thyroid hormone receptor | 0.0218 | 0.3881 | 1 |
Brugia malayi | steroid hormone receptor | 0.0504 | 0.9596 | 0.9596 |
Brugia malayi | Ligand-binding domain of nuclear hormone receptor family protein | 0.0218 | 0.3881 | 0.3881 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.0136 | 0.2246 | 1 |
Echinococcus granulosus | cathepsin l1 | 0.0036 | 0.0236 | 0.0331 |
Echinococcus granulosus | thyroid hormone receptor alpha | 0.0381 | 0.7142 | 1 |
Brugia malayi | Nuclear hormone receptor family member nhr-1 | 0.0218 | 0.3881 | 0.3881 |
Loa Loa (eye worm) | hypothetical protein | 0.0218 | 0.3881 | 0.3881 |
Echinococcus granulosus | nuclear receptor nhr 48 | 0.0095 | 0.1427 | 0.1998 |
Plasmodium falciparum | cysteine proteinase falcipain 3 | 0.0036 | 0.0236 | 0.5 |
Brugia malayi | nuclear hormone receptor family member nhr-6 | 0.0095 | 0.1427 | 0.1427 |
Schistosoma mansoni | retinoic acid receptor RXR | 0.0218 | 0.3881 | 1 |
Brugia malayi | hypothetical protein | 0.0095 | 0.1427 | 0.1427 |
Echinococcus multilocularis | geminin | 0.0168 | 0.2875 | 0.7367 |
Echinococcus granulosus | hepatocyte nuclear factor 4 alpha | 0.0218 | 0.3881 | 0.5434 |
Onchocerca volvulus | Cathepsin L homolog | 0.0036 | 0.0236 | 0.0236 |
Loa Loa (eye worm) | fibroinase | 0.0036 | 0.0236 | 0.0236 |
Brugia malayi | Papain family cysteine protease containing protein | 0.0036 | 0.0236 | 0.0236 |
Schistosoma mansoni | lamin | 0.0027 | 0.0061 | 0.0158 |
Echinococcus granulosus | intermediate filament protein | 0.0027 | 0.0061 | 0.0086 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0036 | 0.0236 | 0.9324 |
Echinococcus multilocularis | cathepsin L cysteine protease | 0.0036 | 0.0236 | 0.0459 |
Brugia malayi | nuclear hormone receptor family member odr-7 | 0.0095 | 0.1427 | 0.1427 |
Schistosoma mansoni | FTZ-F1 nuclear receptor-like protein | 0.0218 | 0.3881 | 1 |
Onchocerca volvulus | Steroid hormone receptor family member cnr14 homolog | 0.0218 | 0.3881 | 0.3881 |
Trypanosoma cruzi | cruzipain precursor, putative | 0.0136 | 0.2246 | 1 |
Echinococcus granulosus | retinoic acid receptor rxr beta a | 0.0218 | 0.3881 | 0.5434 |
Echinococcus granulosus | beta LACTamase domain containing family member | 0.0036 | 0.0242 | 0.0339 |
Echinococcus granulosus | lamin | 0.0027 | 0.0061 | 0.0086 |
Brugia malayi | intermediate filament protein | 0.0027 | 0.0061 | 0.0061 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0036 | 0.0236 | 0.9324 |
Echinococcus granulosus | nuclear receptor 2DBD gamma | 0.0218 | 0.3881 | 0.5434 |
Onchocerca volvulus | 0.0036 | 0.0236 | 0.0236 | |
Schistosoma mansoni | nuclear receptor 2DBD-gamma | 0.0218 | 0.3881 | 1 |
Schistosoma mansoni | cathepsin F (C01 family) | 0.0036 | 0.0236 | 0.0609 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0136 | 0.2246 | 1 |
Echinococcus granulosus | Nuclear hormone receptor HR96 | 0.0095 | 0.1427 | 0.1998 |
Echinococcus multilocularis | COUP TF:Svp nuclear hormone receptor | 0.0218 | 0.3881 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0036 | 0.0236 | 0.9324 |
Onchocerca volvulus | 0.0036 | 0.0236 | 0.0236 | |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0036 | 0.0236 | 0.9324 |
Loa Loa (eye worm) | hypothetical protein | 0.0123 | 0.1975 | 0.1975 |
Brugia malayi | Intermediate filament tail domain containing protein | 0.0027 | 0.0061 | 0.0061 |
Mycobacterium tuberculosis | Probable hydrolase | 0.0036 | 0.0242 | 0.0166 |
Mycobacterium tuberculosis | Probable lipase LipE | 0.0036 | 0.0242 | 0.0166 |
Loa Loa (eye worm) | hypothetical protein | 0.0218 | 0.3881 | 0.3881 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0036 | 0.0236 | 0.9324 |
Echinococcus multilocularis | inositol monophosphatase 1 | 0.0037 | 0.0254 | 0.0503 |
Trichomonas vaginalis | D-aminoacylase, putative | 0.0036 | 0.0242 | 0.9553 |
Mycobacterium ulcerans | extragenic suppressor protein SuhB | 0.0037 | 0.0254 | 1 |
Brugia malayi | GTP-binding regulatory protein Gs alpha-S chain, putative | 0.0046 | 0.0433 | 0.0433 |
Loa Loa (eye worm) | cysteine protease | 0.0036 | 0.0236 | 0.0236 |
Echinococcus granulosus | nuclear receptor subfamily 4 group A | 0.0095 | 0.1427 | 0.1998 |
Brugia malayi | nuclear hormone receptor | 0.0095 | 0.1427 | 0.1427 |
Echinococcus multilocularis | cysteine protease | 0.0036 | 0.0236 | 0.0459 |
Echinococcus multilocularis | cathepsin l cysteine peptidase | 0.0036 | 0.0236 | 0.0459 |
Loa Loa (eye worm) | DR-78 | 0.0095 | 0.1427 | 0.1427 |
Loa Loa (eye worm) | hypothetical protein | 0.0123 | 0.1975 | 0.1975 |
Wolbachia endosymbiont of Brugia malayi | fructose-1,6-bisphosphatase | 0.0037 | 0.0254 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0036 | 0.0236 | 0.0236 |
Trypanosoma cruzi | cysteine peptidase, clan CA, family C1, cathepsin L-like, putative | 0.0124 | 0.201 | 0.8824 |
Brugia malayi | Nuclear hormone receptor E75 | 0.0095 | 0.1427 | 0.1427 |
Entamoeba histolytica | cysteine proteinase, putative | 0.0036 | 0.0236 | 0.9324 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-1 | 0.0218 | 0.3881 | 0.3881 |
Leishmania major | myo-inositol-1(or 4)-monophosphatase 1, putative | 0.0037 | 0.0254 | 0.0085 |
Brugia malayi | Nuclear hormone receptor family member nhr-41 | 0.0218 | 0.3881 | 0.3881 |
Loa Loa (eye worm) | hypothetical protein | 0.0524 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0095 | 0.1427 | 0.1427 |
Schistosoma mansoni | hypothetical protein | 0.0168 | 0.2875 | 0.7409 |
Brugia malayi | Inositol-1 | 0.0037 | 0.0254 | 0.0254 |
Brugia malayi | Nuclear hormone receptor E75 | 0.0095 | 0.1427 | 0.1427 |
Schistosoma mansoni | RAR-like nuclear receptor | 0.0218 | 0.3881 | 1 |
Echinococcus granulosus | cathepsin L cysteine proteinase | 0.0036 | 0.0236 | 0.0331 |
Brugia malayi | Nuclear hormone receptor family member nhr-40 | 0.0218 | 0.3881 | 0.3881 |
Loa Loa (eye worm) | hypothetical protein | 0.0095 | 0.1427 | 0.1427 |
Loa Loa (eye worm) | hypothetical protein | 0.0036 | 0.0242 | 0.0242 |
Loa Loa (eye worm) | hypothetical protein | 0.0095 | 0.1427 | 0.1427 |
Onchocerca volvulus | 0.0218 | 0.3881 | 0.3881 | |
Brugia malayi | Cathepsin L-like precursor | 0.0036 | 0.0236 | 0.0236 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0036 | 0.0236 | 0.9324 |
Brugia malayi | Nuclear hormone receptor-like 1 | 0.0218 | 0.3881 | 0.3881 |
Brugia malayi | Nuclear hormone receptor-like 1 | 0.0123 | 0.1975 | 0.1975 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0036 | 0.0236 | 0.9324 |
Loa Loa (eye worm) | inositol-1 | 0.0037 | 0.0254 | 0.0254 |
Onchocerca volvulus | Cathepsin L homolog | 0.0036 | 0.0236 | 0.0236 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0036 | 0.0236 | 0.9324 |
Mycobacterium leprae | conserved hypothetical protein | 0.0036 | 0.0242 | 1 |
Trichomonas vaginalis | myo inositol monophosphatase, putative | 0.0037 | 0.0254 | 1 |
Brugia malayi | hypothetical protein | 0.0123 | 0.1975 | 0.1975 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-31 | 0.0218 | 0.3881 | 0.3881 |
Loa Loa (eye worm) | hypothetical protein | 0.0123 | 0.1975 | 0.1975 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0036 | 0.0242 | 0.0029 |
Loa Loa (eye worm) | hypothetical protein | 0.0218 | 0.3881 | 0.3881 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0046 | 0.0433 | 0.1115 |
Plasmodium vivax | hypothetical protein, conserved | 0.0036 | 0.0242 | 1 |
Echinococcus multilocularis | nuclear receptor subfamily 4 group A | 0.0095 | 0.1427 | 0.3575 |
Schistosoma mansoni | steroid hormone receptor ad4bp | 0.0218 | 0.3881 | 1 |
Onchocerca volvulus | 0.0036 | 0.0242 | 0.0242 | |
Loa Loa (eye worm) | hypothetical protein | 0.0036 | 0.0242 | 0.0242 |
Echinococcus granulosus | Nuclear hormone receptor family member nhr 41 | 0.0218 | 0.3881 | 0.5434 |
Schistosoma mansoni | intermediate filament proteins | 0.0027 | 0.0061 | 0.0158 |
Echinococcus granulosus | lamin dm0 | 0.0027 | 0.0061 | 0.0086 |
Brugia malayi | ecdysone receptor | 0.0095 | 0.1427 | 0.1427 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-40 | 0.0218 | 0.3881 | 0.3881 |
Loa Loa (eye worm) | hypothetical protein | 0.0218 | 0.3881 | 0.3881 |
Brugia malayi | Nuclear hormone receptor-like 1 | 0.0123 | 0.1975 | 0.1975 |
Brugia malayi | Ligand-binding domain of nuclear hormone receptor family protein | 0.0218 | 0.3881 | 0.3881 |
Mycobacterium tuberculosis | Probable lipase LipD | 0.0036 | 0.0242 | 0.0166 |
Mycobacterium leprae | Probable lipase LipE | 0.0036 | 0.0242 | 1 |
Loa Loa (eye worm) | Papain cysteine protease/cathepsin propeptide inhibitor-containing protein | 0.0036 | 0.0236 | 0.0236 |
Echinococcus granulosus | cathepsin l cysteine peptidase | 0.0036 | 0.0236 | 0.0331 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0036 | 0.0236 | 0.9324 |
Schistosoma mansoni | coup transcription factor | 0.0218 | 0.3881 | 1 |
Schistosoma mansoni | inositol monophosphatase | 0.0037 | 0.0254 | 0.0653 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-14 | 0.0218 | 0.3881 | 0.3881 |
Loa Loa (eye worm) | hypothetical protein | 0.0095 | 0.1427 | 0.1427 |
Mycobacterium tuberculosis | Probable esterase LipL | 0.0036 | 0.0242 | 0.0166 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0136 | 0.2246 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0095 | 0.1427 | 0.1427 |
Echinococcus granulosus | nuclear receptor 2DBD gamma | 0.0095 | 0.1427 | 0.1998 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0046 | 0.0433 | 0.0972 |
Schistosoma mansoni | nuclear hormone receptor | 0.0095 | 0.1427 | 0.3677 |
Brugia malayi | Nuclear hormone receptor family member nhr-25 | 0.0218 | 0.3881 | 0.3881 |
Schistosoma mansoni | cathepsin F (C01 family) | 0.0036 | 0.0236 | 0.0609 |
Trichomonas vaginalis | penicillin-binding protein, putative | 0.0036 | 0.0242 | 0.9553 |
Loa Loa (eye worm) | papain family cysteine protease containing protein | 0.0036 | 0.0236 | 0.0236 |
Loa Loa (eye worm) | hypothetical protein | 0.0218 | 0.3881 | 0.3881 |
Onchocerca volvulus | 0.0036 | 0.0236 | 0.0236 | |
Mycobacterium tuberculosis | Possible conserved lipoprotein LpqK | 0.0036 | 0.0242 | 0.0166 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0036 | 0.0236 | 0.9324 |
Plasmodium falciparum | cysteine proteinase falcipain 2b | 0.0036 | 0.0236 | 0.5 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0136 | 0.2246 | 1 |
Echinococcus multilocularis | beta LACTamase domain containing family member | 0.0036 | 0.0242 | 0.0474 |
Loa Loa (eye worm) | hypothetical protein | 0.0123 | 0.1975 | 0.1975 |
Echinococcus multilocularis | nuclear receptor nhr 48 | 0.0095 | 0.1427 | 0.3575 |
Mycobacterium tuberculosis | Possible penicillin-binding protein | 0.023 | 0.4128 | 1 |
Loa Loa (eye worm) | steroid hormone receptor | 0.0504 | 0.9596 | 0.9596 |
Onchocerca volvulus | 0.0036 | 0.0236 | 0.0236 | |
Onchocerca volvulus | 0.0036 | 0.0236 | 0.0236 | |
Echinococcus multilocularis | Nuclear hormone receptor HR96 | 0.0095 | 0.1427 | 0.3575 |
Onchocerca volvulus | Cathepsin F homolog | 0.0036 | 0.0236 | 0.0236 |
Loa Loa (eye worm) | hypothetical protein | 0.0027 | 0.0051 | 0.0051 |
Echinococcus multilocularis | cathepsin L cysteine protease | 0.0036 | 0.0236 | 0.0459 |
Trichomonas vaginalis | myo inositol monophosphatase, putative | 0.0037 | 0.0254 | 1 |
Onchocerca volvulus | 0.0036 | 0.0236 | 0.0236 | |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0036 | 0.0236 | 0.9324 |
Brugia malayi | Nuclear hormone receptor family member nhr-19 | 0.0218 | 0.3881 | 0.3881 |
Echinococcus multilocularis | Nuclear hormone receptor HR96 | 0.0095 | 0.1427 | 0.3575 |
Echinococcus multilocularis | ecdysone induced protein 78C | 0.0218 | 0.3881 | 1 |
Schistosoma mansoni | hepatocyte nuclear factor 4-alpha (hnf-4-alpha) | 0.0095 | 0.1427 | 0.3677 |
Brugia malayi | Cathepsin L-like precursor | 0.0036 | 0.0236 | 0.0236 |
Loa Loa (eye worm) | hypothetical protein | 0.0095 | 0.1427 | 0.1427 |
Mycobacterium tuberculosis | Probable conserved lipoprotein | 0.0036 | 0.0242 | 0.0166 |
Brugia malayi | Cathepsin L-like precursor | 0.0036 | 0.0236 | 0.0236 |
Echinococcus granulosus | Nuclear hormone receptor HR96 | 0.0095 | 0.1427 | 0.1998 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0036 | 0.0236 | 0.9324 |
Brugia malayi | nuclear receptor NHR-67 | 0.0095 | 0.1427 | 0.1427 |
Entamoeba histolytica | cysteine protease, putative | 0.0036 | 0.0236 | 0.9324 |
Schistosoma mansoni | zinc finger protein | 0.0095 | 0.1427 | 0.3677 |
Onchocerca volvulus | 0.0036 | 0.0236 | 0.0236 | |
Onchocerca volvulus | 0.0095 | 0.1427 | 0.1427 | |
Brugia malayi | nuclear receptor NHR-88 | 0.0095 | 0.1427 | 0.1427 |
Brugia malayi | orphan nuclear receptor NR2E1 | 0.0095 | 0.1427 | 0.1427 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-49 | 0.0218 | 0.3881 | 0.3881 |
Echinococcus multilocularis | Nuclear hormone receptor family member nhr 41 | 0.0218 | 0.3881 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0036 | 0.0236 | 0.9324 |
Brugia malayi | beta-lactamase | 0.0036 | 0.0242 | 0.0242 |
Loa Loa (eye worm) | hypothetical protein | 0.0218 | 0.3881 | 0.3881 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0036 | 0.0236 | 0.9324 |
Brugia malayi | Nuclear hormone receptor family member nhr-49 | 0.0218 | 0.3881 | 0.3881 |
Loa Loa (eye worm) | hypothetical protein | 0.0036 | 0.0242 | 0.0242 |
Loa Loa (eye worm) | nuclear Hormone Receptor family member | 0.0218 | 0.3881 | 0.3881 |
Schistosoma mansoni | nuclear receptor nhr-48 | 0.0095 | 0.1427 | 0.3677 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.0136 | 0.2246 | 1 |
Brugia malayi | nuclear receptor subfamily 1, group D, member 1, putative | 0.0095 | 0.1427 | 0.1427 |
Loa Loa (eye worm) | hypothetical protein | 0.0095 | 0.1427 | 0.1427 |
Brugia malayi | Cathepsin L-like precursor | 0.0036 | 0.0236 | 0.0236 |
Schistosoma mansoni | nuclear receptor | 0.0095 | 0.1427 | 0.3677 |
Brugia malayi | beta-lactamase family protein | 0.0036 | 0.0242 | 0.0242 |
Brugia malayi | Cathepsin L-like precursor | 0.0036 | 0.0236 | 0.0236 |
Loa Loa (eye worm) | hypothetical protein | 0.0218 | 0.3881 | 0.3881 |
Schistosoma mansoni | inositol monophosphatase | 0.0037 | 0.0254 | 0.0653 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0046 | 0.0433 | 0.1115 |
Brugia malayi | nuclear hormone receptor | 0.0218 | 0.3881 | 0.3881 |
Echinococcus granulosus | inositol monophosphatase 1 | 0.0037 | 0.0254 | 0.0355 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-41 | 0.0218 | 0.3881 | 0.3881 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0136 | 0.2246 | 1 |
Entamoeba histolytica | myo-inositol monophosphatase, putative | 0.0037 | 0.0254 | 1 |
Echinococcus multilocularis | FTZ F1 nuclear receptor protein | 0.0218 | 0.3881 | 1 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0046 | 0.0433 | 0.0972 |
Schistosoma mansoni | nuclear hormone receptor | 0.0095 | 0.1427 | 0.3677 |
Toxoplasma gondii | ABC1 family protein | 0.0036 | 0.0242 | 0.3387 |
Schistosoma mansoni | photoreceptor-specific nuclear receptor related | 0.0218 | 0.3881 | 1 |
Activity type | Activity value | Assay description | Source | Reference |
---|---|---|---|---|
Hydrolysis (functional) | < 0.05 | Susceptibility to be hydrolysed by a partially purified cAMP phosphodiesterase from rabbit kidney | ChEMBL. | 6245211 |
I50 (binding) | = 40 uM | Inhibition of cAMP phosphodiesterase preparation from rabbit lung at a substrate concentration of 0.14 microM | ChEMBL. | 6245211 |
I50 (binding) | = 75 uM | Inhibition of cAMP phosphodiesterase preparation from bovine heart at a substrate concentration of 0.14 microM | ChEMBL. | 6245211 |
Ka' (binding) | = 7.8 | Activate a partially purified type II cAMP-dependent protein kinase from bovine brain | ChEMBL. | 6245211 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.
1 literature reference was collected for this gene.