Detailed information for compound 1377278

Basic information

Technical information
  • TDR Targets ID: 1377278
  • Name: N-(4-cyano-3-methyl-1,2-oxazol-5-yl)-2-methox ybenzamide
  • MW: 257.245 | Formula: C13H11N3O3
  • H donors: 1 H acceptors: 3 LogP: 2.18 Rotable bonds: 4
    Rule of 5 violations (Lipinski): 1
  • SMILES: COc1ccccc1C(=O)Nc1onc(c1C#N)C
  • InChi: 1S/C13H11N3O3/c1-8-10(7-14)13(19-16-8)15-12(17)9-5-3-4-6-11(9)18-2/h3-6H,1-2H3,(H,15,17)
  • InChiKey: KOWMKJWIYGWDOM-UHFFFAOYSA-N  

Network

Hover on a compound node to display the structore

Synonyms

  • N-(4-cyano-3-methyl-isoxazol-5-yl)-2-methoxy-benzamide
  • N-(4-cyano-3-methyl-5-isoxazolyl)-2-methoxybenzamide
  • N-(4-cyano-3-methyl-1,2-oxazol-5-yl)-2-methoxy-benzamide
  • N-(4-cyano-3-methyl-5-isoxazolyl)-2-methoxybenzenecarboxamide
  • SMR000335344
  • 3P-398S
  • Oprea1_512509
  • MLS000721153

Targets

Known targets for this compound

Species Target name Source Bibliographic reference
Homo sapiens lamin A/C Starlite/ChEMBL No references

Predicted pathogen targets for this compound

By orthology
Species Potential target Known druggable target/s Ortholog Group
Loa Loa (eye worm) intermediate filament tail domain-containing protein Get druggable targets OG5_128723 All targets in OG5_128723
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_128723 All targets in OG5_128723
Schistosoma mansoni lamin Get druggable targets OG5_128723 All targets in OG5_128723
Echinococcus granulosus lamin dm0 Get druggable targets OG5_128723 All targets in OG5_128723
Schistosoma japonicum ko:K07611 lamin, putative Get druggable targets OG5_128723 All targets in OG5_128723
Brugia malayi intermediate filament protein Get druggable targets OG5_128723 All targets in OG5_128723
Onchocerca volvulus Get druggable targets OG5_128723 All targets in OG5_128723
Echinococcus granulosus cytoplasmic intermediate filament protein Get druggable targets OG5_128723 All targets in OG5_128723
Echinococcus multilocularis musashi Get druggable targets OG5_128723 All targets in OG5_128723
Schistosoma japonicum Intermediate filament protein ifa-1, putative Get druggable targets OG5_128723 All targets in OG5_128723
Echinococcus multilocularis cytoplasmic intermediate filament protein Get druggable targets OG5_128723 All targets in OG5_128723
Loa Loa (eye worm) intermediate filament protein Get druggable targets OG5_128723 All targets in OG5_128723
Schistosoma mansoni intermediate filament proteins Get druggable targets OG5_128723 All targets in OG5_128723
Schistosoma japonicum expressed protein Get druggable targets OG5_128723 All targets in OG5_128723
Echinococcus granulosus intermediate filament protein Get druggable targets OG5_128723 All targets in OG5_128723
Echinococcus multilocularis lamin dm0 Get druggable targets OG5_128723 All targets in OG5_128723
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_128723 All targets in OG5_128723
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_128723 All targets in OG5_128723
Schistosoma japonicum Lamin-C, putative Get druggable targets OG5_128723 All targets in OG5_128723
Schistosoma mansoni lamin Get druggable targets OG5_128723 All targets in OG5_128723
Echinococcus multilocularis lamin Get druggable targets OG5_128723 All targets in OG5_128723
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_128723 All targets in OG5_128723
Onchocerca volvulus Get druggable targets OG5_128723 All targets in OG5_128723
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_128723 All targets in OG5_128723
Echinococcus granulosus lamin Get druggable targets OG5_128723 All targets in OG5_128723
Brugia malayi Intermediate filament tail domain containing protein Get druggable targets OG5_128723 All targets in OG5_128723
Schistosoma japonicum expressed protein Get druggable targets OG5_128723 All targets in OG5_128723

By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity

Obtained from network model

Ranking Plot


Putative Targets List


Species Potential target Raw Global Species
Trichomonas vaginalis MYB72, putative 0.0061 0.0211 0.2125
Echinococcus multilocularis lysosomal alpha glucosidase 0.0158 0.0655 0.1661
Trypanosoma brucei 3', 5'-cyclic nucleotide phosphodiesterase, putative 0.0058 0.0199 0.2758
Echinococcus granulosus sterol regulatory element binding protein 0.0041 0.0123 0.0312
Schistosoma mansoni tar DNA-binding protein 0.0067 0.0241 0.061
Trichomonas vaginalis chromobox protein, putative 0.0034 0.0089 0.0877
Trypanosoma brucei DNA polymerase kappa, putative 0.0142 0.0582 0.8149
Plasmodium vivax holo-[acyl-carrier-protein] synthase, putative 0.0023 0.004 0.0352
Plasmodium vivax SET domain protein, putative 0.003 0.0071 0.0867
Loa Loa (eye worm) sodium/potassium-transporting ATPase subunit alpha 0.0045 0.014 0.0668
Echinococcus multilocularis high affinity cAMP specific 3',5' cyclic 0.0058 0.0199 0.0505
Schistosoma mansoni cation-transporting ATPase 0.0021 0.0031 0.0079
Echinococcus multilocularis mitogen activated protein kinase 0.0049 0.0161 0.0409
Brugia malayi Cathepsin L-like precursor 0.0055 0.0188 0.1025
Trypanosoma brucei DNA polymerase kappa, putative 0.0123 0.0494 0.6908
Trichomonas vaginalis r2r3-MYB transcription factor, putative 0.0061 0.0211 0.2125
Schistosoma mansoni alpha-galactosidase/alpha-n-acetylgalactosaminidase 0.0099 0.0388 0.0984
Trichomonas vaginalis rod cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0058 0.0199 0.1998
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0147 0.0603 0.8436
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0058 0.0199 0.0716
Brugia malayi CXXC zinc finger family protein 0.0028 0.0063 0.0346
Trypanosoma cruzi cruzipain precursor, putative 0.1285 0.5774 1
Trichomonas vaginalis alpha-glucosidase, putative 0.0035 0.0096 0.0948
Trypanosoma cruzi cytochrome P450, putative 0.0015 0.0006 0.0006
Trypanosoma brucei 3', 5'-cyclic nucleotide phosphodiesterase, putative 0.0058 0.0199 0.2758
Echinococcus granulosus thioredoxin glutathione reductase 0.0152 0.0625 0.1585
Echinococcus multilocularis tumor protein p63 0.0328 0.1427 0.3617
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0053 0.0175 0.0298
Trypanosoma brucei vacuolar-type Ca2+-ATPase 1 0.0076 0.0282 0.3921
Mycobacterium ulcerans metal cation-transporting p-type ATPase F, CtpF 0.0089 0.0341 0.0335
Trichomonas vaginalis conserved hypothetical protein 0.0034 0.0089 0.0877
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0034 0.0089 0.0877
Echinococcus multilocularis high affinity cgmp specific 3' 5' cyclic 0.0058 0.0199 0.0505
Echinococcus multilocularis cAMP specific 3',5' cyclic phosphodiesterase 0.0475 0.2093 0.5306
Schistosoma mansoni alpha-glucosidase 0.0136 0.0555 0.1407
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0018 0.0018 0.0047
Toxoplasma gondii melibiase subfamily protein 0.0099 0.0388 0.1398
Brugia malayi hypothetical protein 0.0145 0.0595 0.325
Trichomonas vaginalis PIKK family atypical protein kinase 0.0026 0.0054 0.0518
Trichomonas vaginalis calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative 0.0058 0.0199 0.1998
Trypanosoma brucei P-type H+-ATPase, putative 0.0042 0.0127 0.1749
Toxoplasma gondii Myb family DNA-binding domain-containing protein 0.0061 0.0213 0.0765
Echinococcus granulosus X box binding protein 1 0.028 0.1207 0.306
Brugia malayi MH2 domain containing protein 0.0026 0.0056 0.0306
Trypanosoma brucei DNA polymerase IV, putative 0.0142 0.0582 0.8149
Echinococcus multilocularis cysteine protease 0.0055 0.0188 0.0476
Loa Loa (eye worm) ATP-dependent DNA helicase 0.0018 0.0021 0.0096
Toxoplasma gondii calcium-translocating P-type ATPase, PMCA-type protein 0.0076 0.0282 0.1014
Trypanosoma cruzi trypanothione reductase, putative 0.0152 0.0625 0.1078
Brugia malayi Papain family cysteine protease containing protein 0.0039 0.0116 0.0634
Schistosoma mansoni hypothetical protein 0.005 0.0165 0.0417
Trichomonas vaginalis PIKK family atypical protein kinase 0.0024 0.0044 0.0413
Echinococcus granulosus cytoplasmic intermediate filament protein 0.0016 0.0008 0.002
Echinococcus granulosus lamin 0.0033 0.0085 0.0214
Trichomonas vaginalis glutathione reductase, putative 0.0053 0.0175 0.1756
Brugia malayi cytoplasmic intermediate filament protein 0.0017 0.0016 0.0087
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0053 0.0175 0.0298
Mycobacterium ulcerans metal cation transporter ATPase p-type CtpE 0.0021 0.0031 0.0025
Brugia malayi haloacid dehalogenase-like hydrolase family protein 0.0037 0.0105 0.0576
Loa Loa (eye worm) hypothetical protein 0.0034 0.0089 0.0423
Mycobacterium tuberculosis NADPH-dependent mycothiol reductase Mtr 0.0152 0.0625 0.0833
Brugia malayi calcium ATPase 0.0034 0.0091 0.0497
Mycobacterium ulcerans 4'-phosphopantetheinyl transferase 0.0023 0.004 0.0033
Plasmodium vivax calcium-transporting ATPase, putative 0.0089 0.0341 0.5323
Loa Loa (eye worm) hypothetical protein 0.0058 0.0199 0.0949
Onchocerca volvulus 0.0026 0.0053 0.0362
Entamoeba histolytica cysteine protease, putative 0.0055 0.0188 0.2957
Loa Loa (eye worm) phosphatidylinositol 3 0.0044 0.0135 0.0642
Echinococcus granulosus lipoxygenase domain containing protein 0.0019 0.0024 0.006
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0018 0.0018 0.0156
Entamoeba histolytica cysteine proteinase, putative 0.0039 0.0116 0.1718
Loa Loa (eye worm) cathepsin B 0.0018 0.0018 0.0085
Echinococcus granulosus histone lysine methyltransferase setb 0.003 0.0071 0.018
Echinococcus granulosus L aminoadipate semialdehyde 0.0081 0.0303 0.0769
Plasmodium falciparum holo-[acyl-carrier-protein] synthase, putative 0.0023 0.004 0.0352
Onchocerca volvulus Peroxidasin homolog 0.0026 0.0053 0.0362
Treponema pallidum UDP-N-acetylglucosamine 1-carboxyvinyltransferase 0.2215 1 1
Plasmodium falciparum cGMP-specific phosphodiesterase 0.0058 0.0199 0.2977
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0018 0.0018 0.0156
Trichomonas vaginalis plasma membrane calcium-transporting ATPase, putative 0.0076 0.0282 0.2841
Schistosoma mansoni peroxidasin 0.0026 0.0053 0.0135
Trichomonas vaginalis alpha-glucosidase, putative 0.0035 0.0096 0.0948
Trichomonas vaginalis conserved hypothetical protein 0.0034 0.0089 0.0877
Brugia malayi Animal haem peroxidase family protein 0.0026 0.0053 0.0291
Trichomonas vaginalis conserved hypothetical protein 0.0034 0.0089 0.0877
Trypanosoma cruzi DNA polymerase kappa, putative 0.0142 0.0582 0.1004
Brugia malayi Probable calcium-transporting ATPase KIAA0703 0.0055 0.0185 0.1013
Onchocerca volvulus Chorion peroxidase homolog 0.0026 0.0053 0.0362
Echinococcus multilocularis chromodomain helicase DNA binding protein 4 0.0035 0.0096 0.0244
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0058 0.0199 0.0716
Entamoeba histolytica cysteine protease, putative 0.0039 0.0116 0.1718
Mycobacterium leprae DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE 0.0385 0.1683 0.2316
Trichomonas vaginalis PIKK family atypical protein kinase 0.0032 0.0084 0.0825
Trichomonas vaginalis C-MYB, putative 0.0061 0.0211 0.2125
Plasmodium vivax 3',5'-cyclic nucleotide phosphodiesterase, putative 0.0058 0.0199 0.2977
Trichomonas vaginalis DNA polymerase eta, putative 0.0142 0.0582 0.5904
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0058 0.0199 0.0716
Toxoplasma gondii LsmAD domain-containing protein 0.005 0.0166 0.0595
Brugia malayi 3'5'-cyclic nucleotide phosphodiesterase family protein 0.0058 0.0199 0.1088
Brugia malayi Blistered cuticle protein 3 0.0026 0.0053 0.0291
Plasmodium falciparum thioredoxin reductase 0.0053 0.0175 0.2585
Trichomonas vaginalis CMGC family protein kinase 0.0049 0.0161 0.1613
Schistosoma mansoni DNA polymerase eta 0.0171 0.0714 0.1809
Schistosoma mansoni subfamily C1A unassigned peptidase (C01 family) 0.0018 0.0018 0.0047
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0018 0.0018 0.0047
Trichomonas vaginalis conserved hypothetical protein 0.0018 0.0018 0.0156
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0039 0.0116 0.1151
Trypanosoma cruzi trypanothione reductase, putative 0.0053 0.0175 0.0298
Entamoeba histolytica cysteine proteinase, putative 0.0039 0.0116 0.1718
Brugia malayi E1-E2 ATPase family protein 0.0021 0.0031 0.0171
Trichomonas vaginalis PIKK family atypical protein kinase 0.0035 0.0094 0.0929
Loa Loa (eye worm) hypothetical protein 0.0036 0.01 0.0476
Loa Loa (eye worm) Na,K-ATPase alpha subunit 0.0066 0.0236 0.1127
Loa Loa (eye worm) hypothetical protein 0.0081 0.0303 0.1447
Echinococcus multilocularis protein dispatched 1 0.0047 0.0149 0.0378
Trypanosoma cruzi plasma membrane Ca2+ ATPase 0.0076 0.0282 0.0483
Leishmania major cathepsin L-like protease 0.0055 0.0188 0.2597
Toxoplasma gondii haloacid dehalogenase family hydrolase domain-containing protein 0.0021 0.0031 0.0111
Schistosoma mansoni phosphatidylinositol 3-and 4-kinase 0.0015 0.0003 0.0008
Brugia malayi cathepsin L-like cysteine proteinase, identical 0.0021 0.0034 0.0187
Brugia malayi hypothetical protein 0.005 0.0166 0.0905
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0055 0.0188 0.1881
Echinococcus granulosus intermediate filament protein 0.0033 0.0085 0.0214
Loa Loa (eye worm) hypothetical protein 0.0033 0.0085 0.0401
Loa Loa (eye worm) calcium-transporting ATPase sarcoplasmic/endoplasmic reticulum type 0.0055 0.0185 0.0884
Entamoeba histolytica Plasma membrane calcium-transporting ATPase, putative 0.0076 0.0282 0.4584
Plasmodium vivax ataxin-2 like protein, putative 0.005 0.0166 0.2426
Loa Loa (eye worm) fibroinase 0.0055 0.0188 0.0894
Trichomonas vaginalis cAMP/cGMP cyclic nucleotide phosphodiesterase, putative 0.0058 0.0199 0.1998
Schistosoma mansoni hypothetical protein 0.0047 0.0149 0.0378
Entamoeba histolytica papain family cysteine protease domain containing protein 0.0018 0.0018 0.003
Schistosoma mansoni hypothetical protein 0.0019 0.0024 0.006
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.0055 0.0188 0.1881
Schistosoma mansoni alpha-galactosidase/alpha-n-acetylgalactosaminidase 0.0099 0.0388 0.0984
Trypanosoma brucei DNA polymerase kappa, putative 0.0142 0.0582 0.8149
Trypanosoma brucei DNA polymerase kappa, putative 0.0142 0.0582 0.8149
Loa Loa (eye worm) transcription factor SMAD2 0.0386 0.169 0.8076
Echinococcus multilocularis bloom syndrome protein 0.0045 0.014 0.0355
Leishmania major cysteine peptidase C (CPC),CPC cysteine peptidase, Clan CA, family C1, Cathepsin B-like 0.0018 0.0018 0.0215
Echinococcus multilocularis dihydrolipoamide dehydrogenase 0.0053 0.0175 0.0444
Echinococcus granulosus neuropeptide receptor A26 0.0455 0.2004 0.508
Leishmania major hypothetical protein, conserved 0.0058 0.0199 0.2758
Onchocerca volvulus Heterochromatin protein 1 homolog 0.0094 0.0363 0.3572
Entamoeba histolytica hypothetical protein 0.0034 0.0089 0.1253
Loa Loa (eye worm) phosphatidylinositol 3 0.0015 0.0003 0.0012
Entamoeba histolytica hypothetical protein 0.0023 0.004 0.0399
Entamoeba histolytica cysteine protease, putative 0.0039 0.0116 0.1718
Echinococcus multilocularis cation transporting ATPase 13A3 0.0021 0.0031 0.0079
Trichomonas vaginalis cation-transporting ATPase, putative 0.0089 0.0341 0.345
Loa Loa (eye worm) E1-E2 ATPase 0.0042 0.0127 0.0606
Brugia malayi Sodium/potassium-transporting ATPase alpha chain, putative 0.0045 0.014 0.0766
Trypanosoma brucei cysteine peptidase C (CPC) 0.0018 0.0018 0.0215
Trichomonas vaginalis cGMP-dependent 3,5-cyclic phosphodiesterase, putative 0.0058 0.0199 0.1998
Echinococcus granulosus chromodomain helicase DNA binding protein 4 0.0035 0.0096 0.0244
Trypanosoma brucei cytochrome P450, putative 0.0015 0.0006 0.0048
Mycobacterium tuberculosis Probable reductase 0.0346 0.1508 0.207
Trichomonas vaginalis PIKK family atypical protein kinase 0.0037 0.0106 0.1047
Plasmodium falciparum dihydrolipoyl dehydrogenase, apicoplast 0.0053 0.0175 0.2585
Brugia malayi Cytochrome P450 family protein 0.0025 0.0052 0.0284
Trypanosoma cruzi hypothetical protein, conserved 0.0058 0.0199 0.034
Schistosoma mansoni blooms syndrome DNA helicase 0.0035 0.0097 0.0246
Trichomonas vaginalis Clan CA, family C1, cathepsin L, S or H-like cysteine peptidase 0.0018 0.0018 0.0156
Entamoeba histolytica hypothetical protein 0.0034 0.0089 0.1253
Trypanosoma cruzi calcium motive p-type ATPase, putative 0.0053 0.0177 0.0301
Wolbachia endosymbiont of Brugia malayi dihydrolipoamide dehydrogenase E3 component 0.0053 0.0175 0.0136
Trypanosoma cruzi cysteine peptidase C (CPC), putative 0.0018 0.0018 0.0027
Trypanosoma brucei DNA polymerase kappa, putative 0.0142 0.0582 0.8149
Brugia malayi Cathepsin L-like precursor 0.0055 0.0188 0.1025
Entamoeba histolytica hypothetical protein 0.0034 0.0089 0.1253
Trichomonas vaginalis CMGC family protein kinase 0.0049 0.0161 0.1613
Loa Loa (eye worm) CXXC zinc finger family protein 0.0028 0.0063 0.03
Trichomonas vaginalis PIKK family atypical protein kinase 0.0032 0.0084 0.0825
Brugia malayi ImpB/MucB/SamB family protein 0.0171 0.0714 0.3899
Schistosoma mansoni hypothetical protein 0.0017 0.0012 0.0031
Entamoeba histolytica recQ family helicase, putative 0.0024 0.0045 0.0495
Echinococcus multilocularis peroxidasin 0.0026 0.0053 0.0135
Toxoplasma gondii pyruvate dehydrogenase complex subunit PDH-E3II 0.0053 0.0175 0.063
Brugia malayi hypothetical protein 0.0118 0.0473 0.2586
Loa Loa (eye worm) glutathione reductase 0.0152 0.0625 0.2986
Plasmodium falciparum calcium-transporting ATPase 0.0076 0.0282 0.4337
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0021 0.0034 0.0161
Mycobacterium tuberculosis Probable dehydrogenase 0.0346 0.1508 0.207
Schistosoma mansoni cathepsin F (C01 family) 0.0034 0.009 0.0228
Echinococcus granulosus dnaJ subfamily B 0.0397 0.174 0.4412
Brugia malayi Thioredoxin reductase 0.0152 0.0625 0.3417
Echinococcus multilocularis calcium transporting ATPase type 2C member 0.0089 0.0341 0.0866
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0055 0.0188 0.1881
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0018 0.0018 0.0156
Schistosoma mansoni hypothetical protein 0.0017 0.0012 0.0031
Mycobacterium ulcerans flavoprotein disulfide reductase 0.0053 0.0175 0.0169
Schistosoma mansoni cpg binding protein 0.0029 0.007 0.0179
Loa Loa (eye worm) hypothetical protein 0.0019 0.0024 0.011
Leishmania major mitogen activated protein kinase, putative,map kinase, putative 0.0049 0.0161 0.2227
Loa Loa (eye worm) animal heme peroxidase 0.0026 0.0053 0.0252
Loa Loa (eye worm) hypothetical protein 0.0026 0.0053 0.0252
Giardia lamblia DINP protein human, muc B family 0.0123 0.0494 0.2293
Schistosoma mansoni calcium-transporting atpase sarcoplasmic/endoplasmic reticulum type (calcium pump) 0.0076 0.0282 0.0714
Loa Loa (eye worm) calcium ATPase 0.0047 0.0151 0.0718
Plasmodium vivax unspecified product 0.0039 0.0116 0.1608
Entamoeba histolytica cysteine protease, putative 0.0018 0.0018 0.003
Brugia malayi cahepsin L-like non-peptiedase homolog 0.0018 0.0018 0.01
Leishmania major proton motive ATPase, putative 0.0021 0.0031 0.0396
Leishmania major vacuolar-type Ca2 -ATPase, putative 0.0076 0.0282 0.3921
Trypanosoma brucei target of rapamycin kinase 3, putative 0.0035 0.0094 0.1285
Entamoeba histolytica myb-like DNA-binding domain containing protein 0.0061 0.0211 0.3369
Trypanosoma brucei DNA polymerase kappa, putative 0.0062 0.0218 0.3022
Mycobacterium ulcerans 3-phosphoshikimate 1-carboxyvinyltransferase 0.0625 0.2774 0.2769
Loa Loa (eye worm) hypothetical protein 0.0019 0.0024 0.011
Entamoeba histolytica cysteine proteinase, putative 0.0034 0.009 0.1268
Brugia malayi Protein kinase domain containing protein 0.0014 0.0002 0.0011
Loa Loa (eye worm) ImpB/MucB/SamB family protein 0.0116 0.0465 0.2219
Trypanosoma brucei Phosphatidylinositol 3-kinase tor1 0.0044 0.0135 0.1853
Echinococcus multilocularis terminal deoxycytidyl transferase rev1 0.0116 0.0465 0.1179
Trypanosoma brucei DNA polymerase kappa, putative 0.0062 0.0218 0.3022
Trypanosoma cruzi calcium motive p-type ATPase, putative 0.0053 0.0177 0.0301
Trichomonas vaginalis phospholipid-transporting ATPase, putative 0.0021 0.0031 0.0287
Brugia malayi cathepsin F-like cysteine proteinase 0.0021 0.0034 0.0187
Echinococcus multilocularis Chromo domain 0.0034 0.0089 0.0226
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0017 0.0012 0.0031
Loa Loa (eye worm) hypothetical protein 0.0017 0.0012 0.0056
Trichomonas vaginalis PIKK family atypical protein kinase 0.0026 0.0055 0.053
Onchocerca volvulus 0.0028 0.0063 0.0465
Giardia lamblia DNA damage repair protein 0.0036 0.0101 0.0396
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0053 0.0175 0.2423
Brugia malayi intermediate filament protein 0.0033 0.0085 0.0462
Entamoeba histolytica cysteine protease, putative 0.0018 0.0018 0.003
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0015 0.0003 0.0017
Loa Loa (eye worm) hypothetical protein 0.0018 0.0018 0.0085
Trichomonas vaginalis DNA helicase recq, putative 0.0045 0.014 0.1396
Echinococcus multilocularis neutral alpha glucosidase AB 0.0035 0.0096 0.0243
Trichomonas vaginalis PIKK family atypical protein kinase 0.0044 0.0135 0.1343
Echinococcus multilocularis calcium transporting atpase 0.0076 0.0282 0.0714
Trypanosoma brucei cAMP-specific phosphodiesterase 0.0058 0.0199 0.2758
Echinococcus granulosus phosphatidylinositol 3 and 4 kinase 0.0015 0.0003 0.0008
Echinococcus multilocularis sarco:endoplasmic reticulum calcium ATPase 0.0089 0.0341 0.0866
Plasmodium vivax 3',5'-cyclic nucleotide phosphodiesterase, putative 0.0058 0.0199 0.2977
Echinococcus multilocularis phospholipid transporting ATPase IIB 0.0021 0.0031 0.0079
Brugia malayi cathepsin L-like cysteine proteinase 0.0018 0.0018 0.01
Plasmodium vivax vivapain-2 0.0055 0.0188 0.2788
Schistosoma mansoni alpha-galactosidase/alpha-n-acetylgalactosaminidase 0.0099 0.0388 0.0984
Brugia malayi fibroinase precursor 0.0018 0.0018 0.01
Leishmania major DNA polymerase eta, putative 0.0091 0.0349 0.4873
Loa Loa (eye worm) hypothetical protein 0.003 0.0071 0.0337
Leishmania major cytochrome p450-like protein 0.0015 0.0006 0.0048
Loa Loa (eye worm) follicle stimulating hormone receptor 0.0232 0.0989 0.4726
Onchocerca volvulus 0.0063 0.0223 0.2123
Echinococcus multilocularis Polycystic kidney disease protein 0.0019 0.0024 0.006
Trypanosoma brucei cAMP-specific phosphodiesterase, putative 0.0058 0.0199 0.2758
Loa Loa (eye worm) calcium ATPase 0.0018 0.0017 0.0077
Trypanosoma brucei phosphatidylinositol 4-kinase, putative 0.0044 0.0135 0.1853
Echinococcus multilocularis L aminoadipate semialdehyde 0.0081 0.0303 0.0769
Brugia malayi Glycosyl hydrolases family 31 protein 0.0035 0.0096 0.0525
Trichomonas vaginalis cation-transporting ATPase, putative 0.0076 0.0282 0.2841
Schistosoma mansoni hypothetical protein 0.0145 0.0595 0.1508
Trypanosoma cruzi calcium-transporting ATPase, putative 0.0032 0.008 0.0134
Echinococcus granulosus copper transporting ATPase 1 0.0021 0.0031 0.0079
Loa Loa (eye worm) hypothetical protein 0.0066 0.0238 0.1134
Leishmania major hypothetical protein, conserved 0.005 0.0166 0.2288
Schistosoma mansoni ATPase 0.0089 0.0341 0.0866
Echinococcus multilocularis cation transporting atpase worm 0.0021 0.0031 0.0079
Trypanosoma cruzi DNA polymerase eta, putative 0.0171 0.0714 0.1231
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.004 0.0118 0.117
Trypanosoma cruzi cysteine proteinase, putative 0.0039 0.0116 0.0196
Entamoeba histolytica cysteine protease, putative 0.0039 0.0116 0.1718
Trypanosoma cruzi Phosphatidylinositol 3-kinase tor1 0.0044 0.0135 0.0228
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0055 0.0188 0.1881
Schistosoma mansoni calcium-transporting atpase 2 (atpase 2) 0.0076 0.0282 0.0714
Leishmania major copper-transporting ATPase-like protein, putative 0.0021 0.0031 0.0396
Onchocerca volvulus 0.0055 0.0188 0.1752
Trichomonas vaginalis PIKK family atypical protein kinase 0.0026 0.0055 0.053
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.003 0.0071 0.018
Echinococcus multilocularis phosphatidylinositol 3 and 4 kinase 0.0015 0.0003 0.0008
Loa Loa (eye worm) hypothetical protein 0.0018 0.0018 0.0085
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0055 0.0188 0.0894
Schistosoma mansoni calcium-transporting atpase sarcoplasmic/endoplasmic reticulum type (calcium pump) 0.0076 0.0282 0.0714
Trichomonas vaginalis CMGC family protein kinase 0.0049 0.0161 0.1613
Loa Loa (eye worm) hypothetical protein 0.0026 0.0053 0.0252
Trypanosoma brucei hypothetical protein, conserved 0.0036 0.0101 0.1372
Loa Loa (eye worm) CMGC/MAPK/ERK1 protein kinase 0.0049 0.0161 0.0768
Brugia malayi hypothetical protein 0.023 0.0979 0.535
Loa Loa (eye worm) hypothetical protein 0.0026 0.0053 0.0252
Schistosoma mansoni subfamily C1A unassigned peptidase (C01 family) 0.0018 0.0018 0.0047
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0145 0.0595 0.1508
Loa Loa (eye worm) hypothetical protein 0.0015 0.0005 0.0023
Schistosoma mansoni cathepsin S (C01 family) 0.0018 0.0018 0.0047
Loa Loa (eye worm) hypothetical protein 0.0034 0.009 0.0427
Loa Loa (eye worm) MH2 domain-containing protein 0.0386 0.169 0.8076
Toxoplasma gondii NADPH-glutathione reductase 0.0053 0.0175 0.063
Brugia malayi follicle stimulating hormone receptor 0.0232 0.0989 0.5405
Echinococcus multilocularis Alpha N acetylgalactosaminidase 0.0099 0.0388 0.0984
Loa Loa (eye worm) hypothetical protein 0.0042 0.0126 0.0598
Trichomonas vaginalis high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0058 0.0199 0.1998
Brugia malayi Cathepsin L-like cysteine proteinase 0.0034 0.009 0.0491
Trichomonas vaginalis high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0058 0.0199 0.1998
Trichomonas vaginalis sucrase-isomaltase, putative 0.0035 0.0096 0.0948
Trichomonas vaginalis cyclic nucleotide phosphodiesterase, putative 0.0058 0.0199 0.1998
Plasmodium falciparum cysteine proteinase falcipain 2a 0.0055 0.0188 0.2788
Echinococcus granulosus high affinity cAMP specific 3'5' cyclic 0.0058 0.0199 0.0505
Schistosoma mansoni cathepsin C 0.0018 0.0018 0.0047
Onchocerca volvulus 0.0055 0.0188 0.1752
Echinococcus granulosus Ataxin 2 N terminaldomain containing protein 0.0023 0.0039 0.01
Schistosoma mansoni cgmp-dependent 35-cyclic phosphodiesterase 0.0058 0.0199 0.0505
Trichomonas vaginalis Clan CA, family C1, cathepsin L or H-like cysteine peptidase 0.0018 0.0018 0.0156
Mycobacterium leprae probable 3-phosphoshikimate 1-carboxyvinyl transferase AroA (5-ENOLPYRUVYLSHIKIMATE-3-PHOSPHATE SYNTHASE) (EPSP SYNTHASE) (EPSPS 0.0625 0.2774 0.3845
Echinococcus granulosus chromodomain helicase DNA binding protein 1 0.0034 0.0089 0.0226
Brugia malayi MH1 domain containing protein 0.0015 0.0003 0.0015
Schistosoma mansoni DNA helicase recq1 0.0018 0.0021 0.0052
Wolbachia endosymbiont of Brugia malayi UDP-N-acetylglucosamine 1-carboxyvinyltransferase 0.2215 1 1
Echinococcus multilocularis chromobox protein 2 0.0034 0.0089 0.0226
Entamoeba histolytica cation-transporting P-typeATPase, putative 0.0021 0.0031 0.0252
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0055 0.0188 0.1881
Entamoeba histolytica glycosyl hydrolase, family 31 protein 0.0035 0.0096 0.1373
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0018 0.0018 0.0156
Mycobacterium ulcerans cation transporter p-type ATPase a CtpA 0.0021 0.0031 0.0025
Trypanosoma cruzi cysteine proteinase, putative 0.0039 0.0116 0.0196
Loa Loa (eye worm) hypothetical protein 0.0096 0.0371 0.1769
Echinococcus multilocularis chromodomain helicase DNA binding protein 1 0.0034 0.0089 0.0226
Loa Loa (eye worm) hypothetical protein 0.0048 0.0155 0.0737
Trypanosoma brucei glucosidase, putative 0.0035 0.0096 0.1308
Trypanosoma brucei DNA polymerase kappa, putative 0.0087 0.033 0.4601
Trypanosoma brucei DNA damage repair protein, putative 0.0036 0.0101 0.1372
Echinococcus granulosus cathepsin l1 0.0034 0.009 0.0228
Loa Loa (eye worm) calcium/calmodulin-stimulated cyclic nucleotide phosphodiesterase 0.0058 0.0199 0.0949
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0018 0.0018 0.0156
Trichomonas vaginalis alpha-glucosidase, putative 0.0035 0.0096 0.0948
Entamoeba histolytica cysteine proteinase 1, putative 0.0039 0.0116 0.1718
Onchocerca volvulus Dual oxidase homolog 0.0026 0.0053 0.0362
Trichomonas vaginalis conserved hypothetical protein 0.0034 0.0089 0.0877
Trypanosoma brucei trypanothione reductase 0.0152 0.0625 0.8757
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0028 0.0063 0.0161
Entamoeba histolytica cysteine protease, putative 0.0039 0.0116 0.1718
Schistosoma mansoni DNA polymerase IV / kappa 0.0036 0.0101 0.0255
Loa Loa (eye worm) nuclear factor I 0.0015 0.0003 0.001
Schistosoma mansoni camp-specific 35-cyclic phosphodiesterase 0.0475 0.2093 0.5306
Loa Loa (eye worm) hypothetical protein 0.0121 0.0485 0.2317
Loa Loa (eye worm) hypothetical protein 0.0026 0.0053 0.0252
Brugia malayi calcium ATPase 0.0029 0.0068 0.0369
Trypanosoma cruzi cysteine peptidase, putative 0.0055 0.0188 0.032
Schistosoma mansoni cation-transporting atpase 13a1 (G-box binding protein) 0.0021 0.0031 0.0079
Schistosoma mansoni smad1 5 8 and 0.0026 0.0056 0.0142
Trichomonas vaginalis PIKK family atypical protein kinase 0.0024 0.0044 0.0413
Trypanosoma brucei calcium-translocating P-type ATPase 0.0076 0.0282 0.392
Trichomonas vaginalis conserved hypothetical protein 0.0088 0.0337 0.3404
Trichomonas vaginalis cone cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0058 0.0199 0.1998
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0018 0.0018 0.0156
Toxoplasma gondii shikimate dehydrogenase substrate binding domain-containing protein 0.0625 0.2774 1
Entamoeba histolytica glycosyl hydrolase, family 31 protein 0.0035 0.0096 0.1373
Echinococcus multilocularis chromobox protein 1 0.0149 0.0611 0.155
Trichomonas vaginalis set domain proteins, putative 0.0231 0.0984 1
Trypanosoma brucei vacuolar-type Ca2+-ATPase 2 0.0076 0.0282 0.3921
Schistosoma mansoni hypothetical protein 0.0023 0.0039 0.01
Trypanosoma brucei DNA polymerase IV, putative 0.0136 0.0553 0.774
Loa Loa (eye worm) hypothetical protein 0.0015 0.0003 0.001
Schistosoma mansoni cpg binding protein 0.0029 0.007 0.0179
Trypanosoma cruzi cysteine peptidase, putative 0.0147 0.0603 0.1039
Trichomonas vaginalis conserved hypothetical protein 0.0041 0.0123 0.1222
Schistosoma mansoni patched 1 0.0041 0.0123 0.0312
Trypanosoma brucei DNA damage repair protein, putative 0.0036 0.0101 0.1372
Trichomonas vaginalis conserved hypothetical protein 0.0058 0.0199 0.1998
Trichomonas vaginalis high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0058 0.0199 0.1998
Trypanosoma cruzi plasma-membrane proton-efflux P-type ATPase, putative 0.0029 0.0068 0.0112
Loa Loa (eye worm) hypothetical protein 0.0021 0.0033 0.0154
Plasmodium vivax dihydrolipoyl dehydrogenase, mitochondrial, putative 0.0053 0.0175 0.2585
Echinococcus granulosus cAMP specific 3'5' cyclic phosphodiesterase 0.0417 0.183 0.464
Trichomonas vaginalis high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0058 0.0199 0.1998
Onchocerca volvulus 0.0055 0.0188 0.1752
Chlamydia trachomatis holo [acyl-carrier protein] synthase 0.0023 0.004 0.0009
Trichomonas vaginalis Heterochromatin protein, putative 0.0034 0.0089 0.0877
Giardia lamblia CAMP-specific 3,5-cyclic phosphodiesterase 4B 0.0475 0.2093 1
Trypanosoma cruzi hypothetical protein, conserved 0.0058 0.0199 0.034
Trypanosoma cruzi hypothetical protein, conserved 0.0058 0.0199 0.034
Brugia malayi Cathepsin L-like precursor 0.0055 0.0188 0.1025
Trichomonas vaginalis maltase-glucoamylase, putative 0.0035 0.0096 0.0948
Trichomonas vaginalis PIKK family atypical protein kinase 0.0032 0.0084 0.0825
Schistosoma mansoni microtubule-associated protein tau 0.067 0.298 0.7554
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0145 0.0595 0.1508
Echinococcus multilocularis sterol regulatory element binding protein 0.0041 0.0123 0.0312
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0147 0.0603 0.8436
Schistosoma mansoni ATPase 0.0089 0.0341 0.0866
Echinococcus granulosus Na:K ATPase alpha subunit 0.0053 0.0177 0.0448
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0058 0.0199 0.0716
Entamoeba histolytica cysteine proteinase, putative 0.0055 0.0188 0.2957
Toxoplasma gondii CMGC kinase, MAPK family (ERK) MAPK-1 0.0049 0.0161 0.058
Brugia malayi Animal haem peroxidase family protein 0.0026 0.0053 0.0291
Schistosoma mansoni tar DNA-binding protein 0.0067 0.0241 0.061
Trichomonas vaginalis chromobox protein, putative 0.0149 0.0611 0.6201
Echinococcus granulosus expressed conserved protein 0.009 0.0344 0.0873
Echinococcus granulosus Polycystic kidney disease protein 0.0019 0.0024 0.006
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0036 0.0102 0.1013
Mycobacterium tuberculosis Conserved hypothetical protein 0.0116 0.0465 0.0608
Echinococcus multilocularis lysosomal alpha glucosidase 0.0158 0.0655 0.1661
Giardia lamblia Phospholipid-transporting ATPase IA, putative 0.0021 0.0031 0.0062
Trypanosoma cruzi cysteine peptidase, putative 0.0039 0.0116 0.0196
Trypanosoma cruzi cAMP phosphodiesterase A, putative 0.0058 0.0199 0.034
Loa Loa (eye worm) hypothetical protein 0.0026 0.0053 0.0252
Schistosoma mansoni loxhd1 0.0019 0.0024 0.006
Echinococcus multilocularis cation transporting ATPase 13A1 0.0021 0.0031 0.0079
Trichomonas vaginalis cAMP and cAMP-inhibited cGMP 3,5-cyclic phosphodiesterase, putative 0.0058 0.0199 0.1998
Trichomonas vaginalis conserved hypothetical protein 0.0058 0.0199 0.1998
Echinococcus multilocularis survival motor neuron protein 1 0.023 0.0979 0.2483
Schistosoma mansoni high-affinity cgmp-specific 35-cyclic phosphodiesterase 0.0058 0.0199 0.0505
Mycobacterium tuberculosis Putative ferredoxin reductase 0.0346 0.1508 0.207
Onchocerca volvulus 0.006 0.0211 0.1994
Trichomonas vaginalis cyclic nucleotide phosphodiesterase, putative 0.0058 0.0199 0.1998
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0058 0.0199 0.0716
Loa Loa (eye worm) hypothetical protein 0.0026 0.0053 0.0252
Leishmania major cAMP phosphodiesterase A, putative;with=GeneDB:LinJ18_V3.1100 0.0058 0.0199 0.2758
Loa Loa (eye worm) sodium potassium adenosine triphosphatase 0.0029 0.0068 0.032
Trichomonas vaginalis calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative 0.0058 0.0199 0.1998
Trichomonas vaginalis PIKK family atypical protein kinase 0.0024 0.0043 0.0412
Echinococcus multilocularis Ataxin 2, N terminal,domain containing protein 0.0023 0.0039 0.01
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0018 0.0018 0.0156
Trypanosoma brucei unspecified product 0.0136 0.0553 0.774
Entamoeba histolytica cysteine proteinase, putative 0.0039 0.0116 0.1718
Loa Loa (eye worm) hypothetical protein 0.0089 0.0341 0.1629
Mycobacterium leprae PROBABLE UDP-N-ACETYLGLUCOSAMINE 1-CARBOXYVINYLTRANSFERASE MURA 0.1591 0.7163 1
Trichomonas vaginalis plasma membrane calcium-transporting ATPase, putative 0.0076 0.0282 0.2841
Echinococcus granulosus tar DNA binding protein 0.0067 0.0241 0.061
Echinococcus granulosus TGF beta signal transducer SmadC 0.0026 0.0056 0.0142
Echinococcus granulosus Protein patched homolog 1 0.0041 0.0123 0.0312
Schistosoma mansoni niemann-pick C1 (NPC1) 0.0097 0.0377 0.0957
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0035 0.0096 0.0948
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0058 0.0199 0.0716
Brugia malayi Niemann-Pick C1 protein precursor 0.0096 0.0371 0.2025
Mycobacterium ulcerans phosphopantetheinyl transferase, PptII 0.0023 0.004 0.0033
Trichomonas vaginalis r2r3-MYB transcription factor, putative 0.0061 0.0211 0.2125
Brugia malayi Papain family cysteine protease containing protein 0.0018 0.0018 0.01
Entamoeba histolytica cysteine protease, putative 0.0018 0.0018 0.003
Trichomonas vaginalis cAMP-specific 3,5-cyclic phosphodiesterase, putative 0.0058 0.0199 0.1998
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0018 0.0018 0.0156
Schistosoma mansoni camp-specific cyclic nucleotide phosphodiesterase 0.0058 0.0199 0.0505
Brugia malayi Glycosyl hydrolases family 31 protein 0.0158 0.0655 0.3579
Giardia lamblia Kinase, CMGC MAPK 0.0049 0.0161 0.0689
Trichomonas vaginalis r2r3-MYB transcription factor, putative 0.0061 0.0211 0.2125
Loa Loa (eye worm) hypothetical protein 0.0171 0.0714 0.3408
Entamoeba histolytica myb-like DNA-binding domain containing protein 0.0061 0.0211 0.3369
Echinococcus multilocularis cathepsin b 0.0018 0.0018 0.0047
Entamoeba histolytica cysteine proteinase, putative 0.0055 0.0188 0.2957
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.004 0.0118 0.117
Brugia malayi hypothetical protein 0.0121 0.0486 0.2655
Schistosoma mansoni hypothetical protein 0.0882 0.3945 1
Brugia malayi Calcitonin receptor-like protein seb-1 0.0053 0.0176 0.0961
Echinococcus multilocularis Glycoside hydrolase, family 27 0.0099 0.0388 0.0984
Schistosoma mansoni rab6-interacting 0.0019 0.0024 0.006
Leishmania major acetoin dehydrogenase e3 component-like protein 0.0053 0.0175 0.2423
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0055 0.0188 0.1881
Trypanosoma cruzi hypothetical protein, conserved 0.0058 0.0199 0.034
Plasmodium falciparum ADP-dependent DNA helicase RecQ 0.0039 0.0115 0.1597
Trypanosoma cruzi calcium-translocating P-type ATPase, putative 0.0047 0.0151 0.0256
Schistosoma mansoni plasma membrane calcium-transporting atpase 0.0063 0.0222 0.0562
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0018 0.0018 0.0156
Loa Loa (eye worm) cysteine protease 0.0055 0.0188 0.0894
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0017 0.0012 0.0067
Echinococcus granulosus chromobox protein 1 0.0149 0.0611 0.155
Entamoeba histolytica papain family cysteine protease domain containing protein 0.0018 0.0018 0.003
Schistosoma mansoni aminoadipate-semialdehyde dehydrogenase 0.0081 0.0303 0.0769
Onchocerca volvulus Huntingtin homolog 0.0119 0.0477 0.4746
Trypanosoma cruzi DNA polymerase kappa, putative 0.0142 0.0582 0.1004
Trichomonas vaginalis conserved hypothetical protein 0.0055 0.0184 0.1849
Echinococcus granulosus plasma membrane calcium transporting ATPase 0.0063 0.0222 0.0562
Brugia malayi SET domain containing protein 0.0035 0.0097 0.0528
Schistosoma mansoni tar DNA-binding protein 0.0067 0.0241 0.061
Echinococcus granulosus dna polymerase eta 0.0171 0.0714 0.1809
Echinococcus multilocularis plasma membrane calcium transporting ATPase 0.0063 0.0222 0.0562
Trichomonas vaginalis DNA polymerase IV / kappa, putative 0.0142 0.0582 0.5904
Treponema pallidum 4'-phosphopantetheinyl transferase 0.0023 0.004 0.0009
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0018 0.0018 0.0085
Trichomonas vaginalis pc-MYB2, putative 0.0061 0.0211 0.2125
Leishmania major P-type H -ATPase, putative 0.0042 0.0127 0.1749
Trichomonas vaginalis CMGC family protein kinase 0.0049 0.0161 0.1613
Echinococcus multilocularis cAMP specific 3',5' cyclic phosphodiesterase 0.0417 0.183 0.464
Trypanosoma brucei PAB1-binding protein , putative 0.005 0.0166 0.2288
Entamoeba histolytica plasma membrane calcium-transporting ATPase 1, putative 0.0047 0.0151 0.232
Trypanosoma cruzi cAMP specific phosphodiesterase, putative 0.0058 0.0199 0.034
Leishmania major cysteine peptidase A (CPA) 0.0055 0.0188 0.2597
Schistosoma mansoni hypothetical protein 0.0017 0.0012 0.0031
Plasmodium falciparum conserved Plasmodium protein, unknown function 0.0034 0.0089 0.1165
Brugia malayi Probable 3',5'-cyclic phosphodiesterase C32E12.2, putative 0.0058 0.0199 0.1088
Plasmodium falciparum glutathione reductase 0.0053 0.0175 0.2585
Echinococcus granulosus peroxidasin 0.0026 0.0053 0.0135
Brugia malayi Probable cation-transporting ATPase C10C6.6 in chromosome IV 0.0021 0.0031 0.0171
Trichomonas vaginalis conserved hypothetical protein 0.0037 0.0104 0.1034
Schistosoma mansoni cathepsin F (C01 family) 0.0055 0.0188 0.0476
Toxoplasma gondii cathepsin B 0.0018 0.0018 0.0064
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0058 0.0199 0.0716
Schistosoma mansoni tar DNA-binding protein 0.0067 0.0241 0.061
Brugia malayi hypothetical protein 0.0119 0.0477 0.2605
Echinococcus granulosus cation transporting ATPase 13A1 0.0021 0.0031 0.0079
Echinococcus multilocularis RUN 0.0019 0.0024 0.006
Toxoplasma gondii chromodomain helicase DNA binding protein CHD1/SWI2/SNF2 0.0034 0.0089 0.0319
Trichomonas vaginalis cGMP-inhibited 3,5-cyclic phosphodiesterase, putative 0.0058 0.0199 0.1998
Schistosoma mansoni hypothetical protein 0.0034 0.0089 0.0226
Trypanosoma cruzi cysteine peptidase, putative 0.0147 0.0603 0.1039
Entamoeba histolytica plasma membrane calcium ion-transporting ATPase, putative 0.0047 0.0151 0.232
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0018 0.0018 0.0047
Toxoplasma gondii histone lysine methyltransferase SET1 0.0054 0.0181 0.0652
Mycobacterium tuberculosis Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras 0.0385 0.1683 0.2316
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.004 0.0118 0.117
Trypanosoma cruzi copper-transporting ATPase-like protein, putative 0.0021 0.0031 0.0049
Trichomonas vaginalis cyclic nucleotide phosphodiesterase, putative 0.0058 0.0199 0.1998
Loa Loa (eye worm) hypothetical protein 0.0018 0.0021 0.0096
Trypanosoma cruzi cAMP specific phosphodiesterase, putative 0.0058 0.0199 0.034
Echinococcus multilocularis cathepsin b 0.0018 0.0018 0.0047
Trypanosoma cruzi ATP-dependent DEAD/H DNA helicase recQ, putative 0.0024 0.0045 0.0073
Loa Loa (eye worm) helicase 0.0034 0.0089 0.0423
Leishmania major cathepsin L-like protease 0.0147 0.0603 0.8436
Trichomonas vaginalis plasma membrane calcium-transporting ATPase, putative 0.0076 0.0282 0.2841
Schistosoma mansoni camp-specific 35-cyclic phosphodiesterase 0.0058 0.0199 0.0505
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0017 0.0012 0.0031
Trichomonas vaginalis ATPase, class I, type 8B, putative 0.0021 0.0031 0.0287
Mycobacterium ulcerans metal cation transporter p-type ATPase, CtpV 0.0021 0.0031 0.0025
Schistosoma mansoni terminal deoxycytidyl transferase 0.0116 0.0465 0.1179
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0018 0.0018 0.0047
Leishmania major DNA damage repair protein, putative 0.0036 0.0101 0.1372
Onchocerca volvulus Peroxidase homolog 0.0026 0.0053 0.0362
Trichomonas vaginalis PIKK family atypical protein kinase 0.0024 0.0043 0.0412
Entamoeba histolytica phospholipid-transporting P-type ATPase, putative 0.0021 0.0031 0.0252
Schistosoma mansoni transcription factor LCR-F1 0.0145 0.0595 0.1508
Loa Loa (eye worm) hypothetical protein 0.0021 0.0034 0.0161
Trypanosoma cruzi hypothetical protein, conserved 0.0058 0.0199 0.034
Echinococcus multilocularis cathepsin L cysteine protease 0.0055 0.0188 0.0476
Loa Loa (eye worm) hypothetical protein 0.0021 0.0034 0.0161
Echinococcus multilocularis GPCR, family 2 0.0017 0.0012 0.0031
Loa Loa (eye worm) hypothetical protein 0.0475 0.2093 1
Schistosoma mansoni cpg binding protein 0.0028 0.0063 0.016
Loa Loa (eye worm) hypothetical protein 0.0018 0.0018 0.0085
Brugia malayi hypothetical protein 0.0019 0.0024 0.0129
Brugia malayi Protein cec-1. 0.0034 0.0089 0.0487
Entamoeba histolytica myb-like DNA-binding domain containing protein 0.0061 0.0211 0.3369
Entamoeba histolytica phospholipid-transporting P-type ATPase, putative 0.0021 0.0031 0.0252
Echinococcus multilocularis cpg binding protein 0.0029 0.007 0.0179
Trichomonas vaginalis plasma membrane calcium-transporting ATPase, putative 0.0063 0.0222 0.223
Schistosoma mansoni alpha glucosidase 0.0035 0.0096 0.0243
Onchocerca volvulus 0.0055 0.0188 0.1752
Trichomonas vaginalis r2r3-MYB transcription factor, putative 0.0061 0.0211 0.2125
Trichomonas vaginalis cone cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0058 0.0199 0.1998
Loa Loa (eye worm) hypothetical protein 0.0018 0.0018 0.0085
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0055 0.0188 0.1881
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0055 0.0188 0.1881
Schistosoma mansoni hypothetical protein 0.004 0.0116 0.0295
Trypanosoma cruzi DNA damage repair protein, putative 0.0036 0.0101 0.0169
Plasmodium falciparum ataxin-2 like protein, putative 0.005 0.0166 0.2426
Echinococcus granulosus cysteine protease 0.0039 0.0116 0.0294
Loa Loa (eye worm) hypothetical protein 0.0034 0.0089 0.0423
Onchocerca volvulus 0.0033 0.0085 0.0685
Brugia malayi cathepsin F-like cysteine proteinase 0.0018 0.0018 0.01
Entamoeba histolytica plasma membrane calcium ion-transporting ATPase, putative 0.0039 0.0113 0.1663
Schistosoma mansoni cellular tumor antigen P53 0.0048 0.0155 0.0392
Entamoeba histolytica cysteine protease, putative 0.0018 0.0018 0.003
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.004 0.0118 0.117
Trypanosoma brucei DNA polymerase IV, putative 0.0142 0.0582 0.8149
Echinococcus granulosus Chromobox protein 3 0.0034 0.0089 0.0226
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0055 0.0188 0.1881
Leishmania major hypothetical protein, conserved 0.0058 0.0199 0.2758
Loa Loa (eye worm) hypothetical protein 0.0119 0.0477 0.2276
Toxoplasma gondii BRCA1 C Terminus (BRCT) domain-containing protein 0.0043 0.013 0.0466
Schistosoma mansoni rab6-interacting 0.0019 0.0024 0.006
Plasmodium vivax heterochromatin protein 1, putative 0.0034 0.0089 0.1165
Trichomonas vaginalis cGMP-dependent 3,5-cyclic phosphodiesterase, putative 0.0058 0.0199 0.1998
Plasmodium vivax hypothetical protein, conserved 0.0034 0.0089 0.1165
Onchocerca volvulus Peroxidase homolog 0.0026 0.0053 0.0362
Entamoeba histolytica cysteine protease, putative 0.0039 0.0116 0.1718
Trypanosoma brucei calcium-transporting ATPase, putative 0.0032 0.008 0.1088
Entamoeba histolytica cysteine protease, putative 0.0039 0.0116 0.1718
Plasmodium falciparum non-SERCA-type Ca2+ -transporting P-ATPase 0.0089 0.0341 0.5323
Loa Loa (eye worm) hypothetical protein 0.0308 0.1336 0.638
Schistosoma mansoni chromodomain helicase DNA binding protein 0.0034 0.0089 0.0226
Trypanosoma cruzi major cysteine proteinase, putative 0.0018 0.0018 0.0027
Entamoeba histolytica hypothetical protein 0.0145 0.0595 1
Echinococcus multilocularis Na+:K+ ATPase alpha subunit 0.0053 0.0177 0.0448
Chlamydia trachomatis dihydrolipoyl dehydrogenase 0.0053 0.0175 0.0145
Giardia lamblia Copper-transporting P-type ATPase 0.0021 0.0031 0.0062
Trypanosoma brucei mitogen activated protein kinase 4, putative 0.0049 0.0161 0.2227
Leishmania major cathepsin L-like protease 0.0055 0.0188 0.2597
Leishmania major DNA polymerase kappa, putative 0.0036 0.0101 0.1372
Trichomonas vaginalis cation-transporting ATPase, putative 0.0042 0.0127 0.1267
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0034 0.009 0.0886
Plasmodium falciparum 3',5'-cyclic nucleotide phosphodiesterase, putative 0.0058 0.0199 0.2977
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0055 0.0188 0.1881
Loa Loa (eye worm) hypothetical protein 0.0066 0.0236 0.1127
Brugia malayi glutathione reductase 0.0152 0.0625 0.3417
Chlamydia trachomatis phosphoshikimate 1-carboxyl vinyltransferase 0.0625 0.2774 0.2751
Echinococcus granulosus cAMP specific 3'5' cyclic phosphodiesterase 0.0475 0.2093 0.5306
Echinococcus multilocularis Ca2+ transporting ATPase plasma membrane 0.0063 0.0222 0.0562
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0053 0.0176 0.0961
Brugia malayi CHE-14 protein 0.0041 0.0123 0.0671
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0058 0.0199 0.0716
Plasmodium vivax phosphodiesterase gamma, putative 0.0058 0.0199 0.2977
Mycobacterium tuberculosis Possible DNA-damage-inducible protein P DinP (DNA polymerase V) (pol IV 2) (DNA nucleotidyltransferase (DNA-directed)) 0.0123 0.0494 0.0649
Toxoplasma gondii target of rapamycin (TOR), putative 0.0032 0.0084 0.0301
Trichomonas vaginalis PIKK family atypical protein kinase 0.0035 0.0094 0.0929
Leishmania major cathepsin L-like protease 0.0147 0.0603 0.8436
Trypanosoma cruzi cysteine peptidase, putative 0.0147 0.0603 0.1039
Plasmodium vivax DNA repair protein REV1, putative 0.0036 0.0101 0.1354
Loa Loa (eye worm) hypothetical protein 0.0026 0.0053 0.0252
Trypanosoma cruzi hypothetical protein, conserved 0.0058 0.0199 0.034
Trichomonas vaginalis PIKK family atypical protein kinase 0.0032 0.0084 0.0825
Trypanosoma cruzi PAB1-binding protein , putative 0.005 0.0166 0.0282
Giardia lamblia hypothetical protein 0.0058 0.0199 0.0871
Trichomonas vaginalis PIKK family atypical protein kinase 0.0024 0.0043 0.0412
Plasmodium falciparum glutathione reductase 0.0152 0.0625 1
Loa Loa (eye worm) hypothetical protein 0.0026 0.0053 0.0252
Trypanosoma cruzi DNA damage repair protein, putative 0.0036 0.0101 0.0169
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0034 0.009 0.0886
Trypanosoma cruzi cruzipain precursor, putative 0.0147 0.0603 0.1039
Brugia malayi Cathepsin L-like precursor 0.0034 0.009 0.0491
Onchocerca volvulus 0.0121 0.0485 0.4834
Brugia malayi cathepsin L precursor 0.0018 0.0018 0.01
Trichomonas vaginalis conserved hypothetical protein 0.0055 0.0184 0.1849
Treponema pallidum NADH oxidase 0.0053 0.0175 0.0145
Schistosoma mansoni hypothetical protein 0.028 0.1207 0.306
Brugia malayi Valyl-tRNA synthetase 0.0034 0.0089 0.0487
Schistosoma mansoni copper ABC transporter ATPase 0.0021 0.0031 0.0079
Plasmodium vivax glutathione reductase, putative 0.0152 0.0625 1
Trichomonas vaginalis cGMP-dependent 3,5-cyclic phosphodiesterase, putative 0.0058 0.0199 0.1998
Echinococcus granulosus calcium:calmodulin dependent 3'5' cyclic 0.0058 0.0199 0.0505
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0018 0.0018 0.0047
Leishmania major P-type ATPase, putative 0.0063 0.0222 0.3078
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0055 0.0188 0.1881
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0063 0.0223 0.0567
Trichomonas vaginalis cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0058 0.0199 0.1998
Loa Loa (eye worm) hypothetical protein 0.0034 0.0089 0.0423
Loa Loa (eye worm) hypothetical protein 0.0041 0.0123 0.0585
Brugia malayi polk-prov protein 0.0062 0.0218 0.119
Trichomonas vaginalis cation-transporting ATPase, putative 0.0089 0.0341 0.345
Entamoeba histolytica Plasma membrane calcium-transporting ATPase, putative 0.0076 0.0282 0.4584
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0058 0.0199 0.0716
Leishmania major cathepsin L-like protease 0.0147 0.0603 0.8436
Toxoplasma gondii sarco/endoplasmic reticulum Ca2+-ATPase 0.0089 0.0341 0.1229
Loa Loa (eye worm) cyclic AMP specific phosphodiesterase PDE4D5A 0.0417 0.183 0.8746
Schistosoma mansoni TGF-beta signal transducer Smad2 0.0026 0.0056 0.0142
Echinococcus granulosus mothers against decapentaplegic 5 0.0026 0.0056 0.0142
Echinococcus granulosus smad 0.0026 0.0056 0.0142
Trichomonas vaginalis high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0058 0.0199 0.1998
Echinococcus granulosus phospholipid transporting ATPase IIB 0.0021 0.0031 0.0079
Trypanosoma brucei hypothetical protein, conserved 0.0023 0.004 0.0516
Trypanosoma cruzi hypothetical protein, conserved 0.0035 0.0096 0.0161
Trichomonas vaginalis pc-MYB2, putative 0.0061 0.0211 0.2125
Schistosoma mansoni retinoblastoma-binding protein 4 (rbbp4) 0.0014 0.0001 0.0001
Schistosoma mansoni subfamily C1A non-peptidase homologue (C01 family) 0.0018 0.0018 0.0047
Brugia malayi Animal haem peroxidase family protein 0.0026 0.0053 0.0291
Echinococcus multilocularis dna polymerase eta 0.0171 0.0714 0.1809
Brugia malayi Papain family cysteine protease containing protein 0.0039 0.0116 0.0634
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0058 0.0199 0.0716
Brugia malayi hypothetical protein 0.0019 0.0024 0.0129
Brugia malayi hypothetical protein 0.0026 0.0053 0.0291
Loa Loa (eye worm) hypothetical protein 0.0044 0.0138 0.0656
Plasmodium vivax vivapain-1 0.0039 0.0116 0.1608
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0055 0.0188 0.1881
Brugia malayi Cytochrome P450 family protein 0.0015 0.0006 0.0035
Loa Loa (eye worm) hypothetical protein 0.0018 0.0018 0.0085
Trypanosoma cruzi cysteine peptidase C (CPC), putative 0.0018 0.0018 0.0027
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.0033 0.0085 0.0401
Leishmania major target of rapamycin kinase (TOR) kinase 3 0.0035 0.0094 0.1285
Schistosoma mansoni smad 0.0026 0.0056 0.0142
Echinococcus multilocularis Ankyrin repeat domain containing protein 0.0087 0.0333 0.0844
Echinococcus multilocularis Smad4 0.0026 0.0056 0.0142
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0147 0.0603 0.8436
Loa Loa (eye worm) PDE1B protein 0.0058 0.0199 0.0949
Leishmania major phosphopantetheinyl transferase-like protein 0.0023 0.004 0.0516
Echinococcus granulosus terminal deoxycytidyl transferase rev1 0.0116 0.0465 0.1179
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0018 0.0018 0.0156
Schistosoma mansoni survival motor neuron protein 0.0047 0.0149 0.0378
Brugia malayi Cathepsin L-like precursor 0.0055 0.0188 0.1025
Onchocerca volvulus 0.0026 0.0053 0.0362
Brugia malayi Calcium-transporting ATPase sarcoplasmic/endoplasmic reticulum type 0.0076 0.0282 0.1538
Toxoplasma gondii 4'-phosphopantetheinyl transferase domain-containing protein 0.0023 0.004 0.0141
Loa Loa (eye worm) doublecortin family protein 0.0019 0.0024 0.011
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0053 0.0175 0.0298
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.003 0.0071 0.0254
Trichomonas vaginalis PIKK family atypical protein kinase 0.0024 0.0044 0.0413
Plasmodium falciparum chromodomain-helicase-DNA-binding protein 1 homolog, putative 0.0034 0.0089 0.1165
Trichomonas vaginalis chromobox protein, putative 0.0094 0.0363 0.3675
Echinococcus granulosus dihydrolipoamide dehydrogenase 0.0053 0.0175 0.0444
Loa Loa (eye worm) hypothetical protein 0.0034 0.009 0.0427
Trypanosoma cruzi cysteine peptidase, clan CA, family C1, cathepsin L-like, putative 0.0125 0.0505 0.087
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0039 0.0116 0.1151
Loa Loa (eye worm) Smad1 0.0026 0.0056 0.0266
Toxoplasma gondii glycosyl hydrolase, family 31 protein 0.0035 0.0096 0.0344
Brugia malayi aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase 0.0081 0.0303 0.1657
Loa Loa (eye worm) cytochrome P450 family protein 0.0025 0.0052 0.0246
Toxoplasma gondii cathepsin CPL 0.0055 0.0188 0.0675
Echinococcus multilocularis Niemann Pick C1 protein 0.0096 0.0371 0.094
Trichomonas vaginalis conserved hypothetical protein 0.0088 0.0337 0.3404
Schistosoma mansoni camp/cgmp cyclic nucleotide phosphodiesterase 0.0058 0.0199 0.0505
Echinococcus multilocularis lamin dm0 0.0033 0.0085 0.0214
Entamoeba histolytica cysteine protease, putative 0.0039 0.0116 0.1718
Echinococcus granulosus Ca2 transporting ATPase plasma membrane 0.0063 0.0222 0.0562
Toxoplasma gondii cathepsin CPC1 0.0018 0.0018 0.0064
Schistosoma mansoni Smad4 0.0026 0.0056 0.0142
Echinococcus multilocularis cathepsin L cysteine protease 0.0055 0.0188 0.0476
Brugia malayi Papain family cysteine protease containing protein 0.0018 0.0018 0.01
Mycobacterium tuberculosis NAD(P)H quinone reductase LpdA 0.0385 0.1683 0.2316
Brugia malayi cathepsin B-like cysteine proteinase 0.0018 0.0018 0.01
Entamoeba histolytica hypothetical protein 0.0018 0.0018 0.003
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0058 0.0199 0.0716
Schistosoma mansoni DNA helicase recq5 0.0018 0.0021 0.0052
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0034 0.0089 0.0877
Echinococcus granulosus cation transporting ATPase 13A3 0.0021 0.0031 0.0079
Schistosoma mansoni dihydrolipoamide dehydrogenase 0.0053 0.0175 0.0444
Brugia malayi CHD4 protein 0.0035 0.0096 0.0526
Echinococcus granulosus lysosomal alpha glucosidase 0.0158 0.0655 0.1661
Trypanosoma cruzi hypothetical protein, conserved 0.0035 0.0096 0.0161
Echinococcus multilocularis expressed conserved protein 0.009 0.0344 0.0873
Entamoeba histolytica hypothetical protein 0.0145 0.0595 1
Mycobacterium tuberculosis Probable metal cation transporter P-type ATPase A CtpF 0.0023 0.0042 0.0015
Entamoeba histolytica deoxycytidyl transferase, putative 0.0116 0.0465 0.7753
Schistosoma mansoni chromobox protein 0.0034 0.0089 0.0226
Onchocerca volvulus Cathepsin F homolog 0.0055 0.0188 0.1752
Schistosoma mansoni hypothetical protein 0.004 0.0116 0.0295
Trichomonas vaginalis calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative 0.0058 0.0199 0.1998
Plasmodium falciparum cysteine proteinase falcipain 1 0.0039 0.0116 0.1608
Brugia malayi hypothetical protein 0.0033 0.0084 0.0461
Echinococcus multilocularis ATP dependent DNA helicase Q5 0.0018 0.0021 0.0052
Entamoeba histolytica cysteine protease, putative 0.0039 0.0116 0.1718
Brugia malayi 3'5'-cyclic nucleotide phosphodiesterase family protein 0.0058 0.0199 0.1088
Loa Loa (eye worm) MH2 domain-containing protein 0.0026 0.0056 0.0266
Plasmodium vivax hypothetical protein, conserved 0.0034 0.0089 0.1165
Loa Loa (eye worm) hypothetical protein 0.0039 0.0113 0.0536
Mycobacterium ulcerans metal cation-transporting p-type ATPase CtpC 0.0021 0.0031 0.0025
Onchocerca volvulus 0.0055 0.0188 0.1752
Brugia malayi Animal haem peroxidase family protein 0.0026 0.0053 0.0291
Trypanosoma cruzi major cysteine proteinase, putative 0.0109 0.0433 0.0746
Schistosoma mansoni dipeptidyl-peptidase I (C01 family) 0.0018 0.0018 0.0047
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.003 0.0071 0.018
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0018 0.0018 0.0047
Echinococcus granulosus Alpha N acetylgalactosaminidase 0.0099 0.0388 0.0984
Trichomonas vaginalis conserved hypothetical protein 0.0034 0.0089 0.0877
Entamoeba histolytica chromodomain-helicase-DNA-binding protein, putative 0.0034 0.0089 0.1253
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0058 0.0199 0.0716
Echinococcus multilocularis neuropeptide s receptor 0.0455 0.2004 0.508
Plasmodium vivax cation transporting ATPase, putative 0.0021 0.0031 0.0212
Entamoeba histolytica cysteine protease, putative 0.0039 0.0116 0.1718
Brugia malayi Probable 3',5'-cyclic phosphodiesterase R153.1, putative 0.0417 0.183 1
Plasmodium falciparum cysteine proteinase falcipain 3 0.0055 0.0188 0.2788
Loa Loa (eye worm) hypothetical protein 0.0088 0.0337 0.1608
Trypanosoma brucei dihydrolipoyl dehydrogenase 0.0053 0.0175 0.2423
Echinococcus multilocularis X box binding protein 1 0.028 0.1207 0.306
Brugia malayi Type III restriction enzyme, res subunit family protein 0.0034 0.0089 0.0487
Schistosoma mansoni multiple ankyrin repeats single kh domain protein 0.0087 0.0333 0.0844
Brugia malayi Cathepsin L-like precursor 0.0021 0.0034 0.0187
Onchocerca volvulus 0.0033 0.0085 0.0685
Brugia malayi Heterochromatin protein 1 0.0149 0.0611 0.334
Loa Loa (eye worm) animal heme peroxidase 0.0026 0.0053 0.0252
Echinococcus granulosus arachidonate 5 lipoxygenase 0.0054 0.018 0.0456
Echinococcus multilocularis cysteine protease 0.0055 0.0188 0.0476
Mycobacterium ulcerans dihydrolipoamide dehydrogenase, LpdB 0.0053 0.0175 0.0169
Trypanosoma cruzi Phosphatidylinositol 3-kinase tor2 0.0044 0.0135 0.0228
Loa Loa (eye worm) thioredoxin reductase 0.0152 0.0625 0.2986
Echinococcus multilocularis calcium:calmodulin dependent 3',5' cyclic 0.0058 0.0199 0.0505
Wolbachia endosymbiont of Brugia malayi dihydrolipoamide dehydrogenase E3 component 0.0053 0.0175 0.0136
Brugia malayi Cathepsin L-like precursor 0.0055 0.0188 0.1025
Trypanosoma cruzi plasma membrane Ca2+ ATPase 0.0076 0.0282 0.0483
Trypanosoma cruzi DNA polymerase eta, putative 0.0091 0.0349 0.06
Schistosoma mansoni na+/k+ atpase alpha subunit 0.0053 0.0177 0.0448
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0055 0.0188 0.1881
Schistosoma mansoni lamin 0.0033 0.0085 0.0214
Echinococcus multilocularis nuclear factor of activated T cells 5 0.0071 0.0261 0.0663
Onchocerca volvulus 0.0066 0.0236 0.2257
Loa Loa (eye worm) intermediate filament protein 0.0033 0.0085 0.0401
Loa Loa (eye worm) hypothetical protein 0.0024 0.0046 0.0215
Schistosoma mansoni chromobox protein 0.0149 0.0611 0.155
Trichomonas vaginalis high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0058 0.0199 0.1998
Schistosoma mansoni hypothetical protein 0.0882 0.3945 1
Plasmodium vivax dihydrolipoyl dehydrogenase, apicoplast, putative 0.0053 0.0175 0.2585
Trichomonas vaginalis rod cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0058 0.0199 0.1998
Echinococcus multilocularis arachidonate 5 lipoxygenase 0.0054 0.018 0.0456
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0147 0.0603 0.8436
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.0039 0.0116 0.0294
Toxoplasma gondii preprocathepsin c precursor, putative 0.0018 0.0018 0.0064
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0053 0.0175 0.2423
Trypanosoma brucei DNA polymerase kappa, putative 0.0142 0.0582 0.8149
Plasmodium falciparum ataxin-2 like protein, putative 0.005 0.0166 0.2426
Trypanosoma cruzi cAMP specific phosphodiesterase, putative 0.0058 0.0199 0.034
Plasmodium falciparum copper-transporting ATPase 0.0021 0.0031 0.0212
Schistosoma mansoni lipoxygenase 0.0054 0.018 0.0456
Echinococcus granulosus mitogen activated protein kinase 3 0.0049 0.0161 0.0409
Echinococcus multilocularis Chromobox protein 3 0.0034 0.0089 0.0226
Brugia malayi MH1 domain containing protein 0.0015 0.0003 0.0015
Brugia malayi cathepsin L-like precursor 0.0034 0.009 0.0491
Echinococcus granulosus plasma membrane calcium transporting ATPase 2 0.0076 0.0282 0.0714
Trichomonas vaginalis cation-transporting ATPase, putative 0.0021 0.0031 0.0287
Toxoplasma gondii ImpB/MucB/SamB family protein 0.0036 0.0101 0.0361
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0058 0.0199 0.0716
Echinococcus multilocularis geminin 0.0882 0.3945 1
Trichomonas vaginalis cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0058 0.0199 0.1998
Brugia malayi Probable 3',5'-cyclic phosphodiesterase R153.1, putative 0.0058 0.0199 0.1088
Leishmania major cathepsin L-like protease 0.0055 0.0188 0.2597
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0053 0.0176 0.0838
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0017 0.0012 0.0031
Giardia lamblia GTOR 0.0044 0.0135 0.0561
Onchocerca volvulus 0.0121 0.0485 0.4834
Onchocerca volvulus Peroxidasin homolog 0.0026 0.0053 0.0362
Echinococcus multilocularis chromobox protein 1 0.0149 0.0611 0.155
Loa Loa (eye worm) hypothetical protein 0.0021 0.0031 0.0147
Trichomonas vaginalis DNA helicase recq1, putative 0.0045 0.014 0.1396
Onchocerca volvulus 0.0055 0.0188 0.1752
Giardia lamblia Plasma membrane calcium-transporting ATPase 2 0.0053 0.0177 0.0762
Brugia malayi alpha keto acid dehydrogenase complex, E3 component, lipoamide dehydrogenase 0.0039 0.0112 0.0611
Onchocerca volvulus Cathepsin L homolog 0.0055 0.0188 0.1752
Echinococcus granulosus Chromo domain 0.0034 0.0089 0.0226
Mycobacterium tuberculosis Possible metal cation transporting P-type ATPase CtpH 0.0045 0.014 0.0153
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0058 0.0199 0.0716
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0039 0.0116 0.1589
Plasmodium vivax vivapain-2 0.0055 0.0188 0.2788
Brugia malayi RNA binding protein 0.0067 0.0241 0.1315
Brugia malayi Peroxidasin 0.0026 0.0053 0.0291
Echinococcus granulosus bloom syndrome protein 0.0045 0.014 0.0355
Brugia malayi latrophilin 2 splice variant baaae 0.0036 0.01 0.0547
Loa Loa (eye worm) hypothetical protein 0.0058 0.0199 0.0949
Entamoeba histolytica chromodomain-helicase-DNA-binding protein, putative 0.0034 0.0089 0.1253
Trichomonas vaginalis hypothetical protein 0.0034 0.0089 0.0877
Leishmania major alpha glucosidase II subunit, putative 0.0035 0.0096 0.1308
Trypanosoma cruzi P-type H+-ATPase, putative 0.0042 0.0127 0.0215
Plasmodium falciparum 3',5'-cyclic nucleotide phosphodiesterase, putative 0.0058 0.0199 0.2977
Trypanosoma brucei hypothetical protein, conserved 0.0058 0.0199 0.2758
Trichomonas vaginalis cation-transporting ATPase fungi, putative 0.0076 0.0282 0.2841
Trichomonas vaginalis PIKK family atypical protein kinase 0.0035 0.0094 0.0929
Onchocerca volvulus 0.0026 0.0053 0.0362
Trichomonas vaginalis PIKK family atypical protein kinase 0.0032 0.0084 0.0825
Brugia malayi Melibiase family protein 0.0066 0.0238 0.1299
Loa Loa (eye worm) hypothetical protein 0.0034 0.0089 0.0423
Echinococcus multilocularis lipoxygenase domain containing protein 0.0019 0.0024 0.006
Echinococcus granulosus cAMP specific 3'5' cyclic phosphodiesterase 0.0475 0.2093 0.5306
Brugia malayi Doublecortin family protein 0.0019 0.0024 0.0129
Leishmania major trypanothione reductase 0.0152 0.0625 0.8757
Brugia malayi RNA recognition motif domain containing protein 0.0067 0.0241 0.1315
Plasmodium vivax ADP-dependent DNA helicase RecQ, putative 0.003 0.0074 0.0919
Loa Loa (eye worm) hypothetical protein 0.0058 0.0199 0.0949
Echinococcus multilocularis cathepsin L 0.0039 0.0116 0.0294
Plasmodium falciparum dihydrolipoyl dehydrogenase, mitochondrial 0.0053 0.0175 0.2585
Leishmania major calcium-translocating P-type ATPase 0.0089 0.0341 0.4762
Plasmodium falciparum phosphodiesterase gamma, putative 0.0058 0.0199 0.2977
Echinococcus granulosus Niemann Pick C1 protein 0.0137 0.0557 0.1412
Brugia malayi M-phase phosphoprotein, mpp8 0.0121 0.0485 0.2652
Leishmania major target of rapamycin (TOR) kinase 1, putative 0.0044 0.0135 0.1853
Entamoeba histolytica phospholipid-transporting P-type ATPase, putative 0.0021 0.0031 0.0252
Trichomonas vaginalis Clan CA, family C1, cathepsin H-like cysteine peptidase 0.0018 0.0018 0.0156
Trichomonas vaginalis C-MYB, putative 0.0061 0.0211 0.2125
Loa Loa (eye worm) hypothetical protein 0.0021 0.0031 0.0147
Trichomonas vaginalis PIKK family atypical protein kinase 0.0029 0.007 0.0678
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.003 0.0071 0.018
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0039 0.0116 0.1589
Trypanosoma cruzi DNA polymerase kappa, putative 0.0142 0.0582 0.1004
Echinococcus granulosus lamin dm0 0.0033 0.0085 0.0214
Trypanosoma brucei DNA polymerase kappa, putative 0.0087 0.033 0.4601
Plasmodium vivax P-type ATPase4, putative 0.0089 0.0341 0.5323
Loa Loa (eye worm) hypothetical protein 0.0026 0.0053 0.0252
Loa Loa (eye worm) hypothetical protein 0.0119 0.0477 0.2276
Echinococcus granulosus RUN 0.0019 0.0024 0.006
Trichomonas vaginalis PIKK family atypical protein kinase 0.0044 0.0135 0.1343
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0147 0.0603 0.8436
Brugia malayi Sodium/potassium-transporting ATPase alpha-3 chain, putative 0.0029 0.0068 0.0369
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0147 0.0603 0.8436
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0053 0.0175 0.0298
Trypanosoma cruzi cation-transporting ATPase, putative 0.0021 0.0031 0.0049
Echinococcus granulosus geminin 0.0882 0.3945 1
Toxoplasma gondii plasma membrane-type Ca(2+)-ATPase A1 PMCAA1 0.0063 0.0222 0.0798
Trypanosoma brucei ATP-dependent DEAD/H DNA helicase recQ, putative 0.0024 0.0045 0.0594
Loa Loa (eye worm) animal heme peroxidase 0.0026 0.0053 0.0252
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0018 0.0018 0.0156
Schistosoma mansoni hypothetical protein 0.0017 0.0012 0.0031
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0018 0.0018 0.0047
Leishmania major cathepsin L-like protease 0.0055 0.0188 0.2597
Echinococcus granulosus Smad4 0.0026 0.0056 0.0142
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.0039 0.0116 0.0294
Echinococcus granulosus cation transporting atpase worm 0.0021 0.0031 0.0079
Mycobacterium leprae PROBABLE CATION-TRANSPORTER ATPASE I CTPI 0.0045 0.014 0.0153
Brugia malayi ATP-dependent DNA helicase, RecQ family protein 0.0018 0.0021 0.0112
Loa Loa (eye worm) hypothetical protein 0.0018 0.0018 0.0085
Trypanosoma cruzi copper-transporting ATPase-like protein, putative 0.0021 0.0031 0.0049
Loa Loa (eye worm) animal heme peroxidase 0.0026 0.0053 0.0252
Trypanosoma brucei DNA polymerase eta, putative 0.0171 0.0714 1
Leishmania major cAMP-specific phosphodiesterase, putative 0.0058 0.0199 0.2758
Echinococcus multilocularis cytoplasmic intermediate filament protein 0.0016 0.0008 0.002
Trypanosoma brucei DNA polymerase kappa, putative 0.0142 0.0582 0.8149
Loa Loa (eye worm) hypothetical protein 0.0026 0.0053 0.0252
Loa Loa (eye worm) Papain cysteine protease/cathepsin propeptide inhibitor-containing protein 0.0055 0.0188 0.0894
Schistosoma mansoni serine/threonine protein kinase 0.0049 0.0161 0.0409
Echinococcus granulosus mitogen activated protein kinase 0.0049 0.0161 0.0409
Brugia malayi Na,K-ATPase alpha subunit 0.0066 0.0236 0.1291
Schistosoma mansoni Na+/K+ transporting ATPase subunit alpha 0.0066 0.0236 0.0599
Plasmodium vivax unspecified product 0.0021 0.0034 0.0262
Mycobacterium tuberculosis Probable oxidoreductase 0.0385 0.1683 0.2316
Schistosoma mansoni camp-specific 35-cyclic phosphodiesterase 0.0058 0.0199 0.0505
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.003 0.0071 0.018
Brugia malayi Cathepsin L-like precursor 0.0055 0.0188 0.1025
Schistosoma mansoni chromobox protein 0.0149 0.0611 0.155
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.003 0.0071 0.018
Loa Loa (eye worm) hypothetical protein 0.0053 0.0176 0.0838
Leishmania major DNA polymerase eta, putative 0.0171 0.0714 1
Echinococcus multilocularis cAMP specific 3',5' cyclic phosphodiesterase 0.0475 0.2093 0.5306
Brugia malayi Membrane calcium atpase protein 3 0.0063 0.0222 0.1212
Trypanosoma brucei protein kinase, putative 0.0049 0.0161 0.2227
Loa Loa (eye worm) CHromoDomain protein family member 0.0035 0.0096 0.0458
Leishmania major 2-oxoglutarate dehydrogenase, e3 component, lipoamidedehydrogenase-like protein 0.0053 0.0175 0.2423
Schistosoma mansoni tar DNA-binding protein 0.0067 0.0241 0.061
Trypanosoma cruzi Calcium ATPase SERCA-like 0.0089 0.0341 0.0586
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0018 0.0018 0.0156
Trichomonas vaginalis PIKK family atypical protein kinase 0.0044 0.0135 0.1343
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0147 0.0603 0.8436
Trichomonas vaginalis cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0058 0.0199 0.1998
Brugia malayi MAP kinase sur-1 0.0049 0.0161 0.0881
Loa Loa (eye worm) hypothetical protein 0.0026 0.0053 0.0252
Trypanosoma cruzi calcium-translocating P-type ATPase, putative 0.0029 0.0068 0.0112
Brugia malayi cathepsin Z-like cysteine proteinase 0.0018 0.0018 0.01
Schistosoma mansoni lamin 0.0033 0.0085 0.0214
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0147 0.0603 0.8436
Echinococcus granulosus high affinity cgmp specific 3' 5' cyclic 0.0058 0.0199 0.0505
Mycobacterium tuberculosis Probable UDP-N-acetylglucosamine 1-carboxyvinyltransferase MurA 0.1591 0.7163 1
Trichomonas vaginalis alpha-glucosidase, putative 0.0035 0.0096 0.0948
Trypanosoma cruzi cyclic nucleotide phosphodiesterase 0.0058 0.0199 0.034
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0018 0.0018 0.0047
Echinococcus multilocularis Tetracycline resistance leader peptide, TetL 0.0076 0.0282 0.0714
Mycobacterium ulcerans cation-transporter p-type ATPase B CtpB 0.0021 0.0031 0.0025
Echinococcus granulosus Ankyrin 0.0014 0.0001 0.0001
Loa Loa (eye worm) hypothetical protein 0.0021 0.0031 0.0147
Schistosoma mansoni ataxia telangiectasia mutated (atm)-related 0.0044 0.0135 0.0342
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.0039 0.0116 0.0294
Echinococcus multilocularis mitogen activated protein kinase 3 0.0049 0.0161 0.0409
Trichomonas vaginalis PIKK family atypical protein kinase 0.0035 0.0094 0.0929
Plasmodium vivax cyclic nucleotide phosphodiesterase, putative 0.0058 0.0199 0.2977
Plasmodium falciparum DNA repair protein REV1, putative 0.0036 0.0101 0.1354
Echinococcus granulosus cathepsin L cysteine protease 0.0039 0.0116 0.0294
Mycobacterium ulcerans DNA polymerase IV 0.0142 0.0582 0.0576
Brugia malayi Smad1 0.0026 0.0056 0.0306
Trichomonas vaginalis PIKK family atypical protein kinase 0.0028 0.0065 0.0634
Echinococcus granulosus chromobox protein 1 0.0149 0.0611 0.155
Onchocerca volvulus 0.0034 0.009 0.0741
Trichomonas vaginalis PIKK family atypical protein kinase 0.0032 0.0084 0.0825
Mycobacterium tuberculosis Probable soluble pyridine nucleotide transhydrogenase SthA (STH) (NAD(P)(+) transhydrogenase [B-specific]) (nicotinamide nucleot 0.0053 0.0175 0.0202
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0058 0.0199 0.0716
Trichomonas vaginalis chromobox protein, putative 0.0034 0.0089 0.0877
Trichomonas vaginalis cGMP-inhibited 3,5-cyclic phosphodiesterase, putative 0.0058 0.0199 0.1998
Trichomonas vaginalis cAMP-specific phosphodiesterase, putative 0.0058 0.0199 0.1998
Loa Loa (eye worm) hypothetical protein 0.0034 0.0089 0.0423
Loa Loa (eye worm) hypothetical protein 0.0062 0.0218 0.1038
Loa Loa (eye worm) glycosyl hydrolase family 31 protein 0.0035 0.0096 0.0456
Echinococcus granulosus cathepsin L 0.0039 0.0116 0.0294
Plasmodium vivax multidomain scavenger receptor, putative 0.0019 0.0024 0.0086
Entamoeba histolytica FKBP-rapamycin associated protein (FRAP), putative 0.0044 0.0135 0.2043
Toxoplasma gondii 4'-phosphopantetheinyl transferase superfamily protein 0.0023 0.004 0.0141
Trichomonas vaginalis conserved hypothetical protein 0.0034 0.0089 0.0877
Entamoeba histolytica myb-like DNA-binding domain containing protein 0.0061 0.0211 0.3369
Schistosoma mansoni high-affinity cgmp-specific 35-cyclic phosphodiesterase 0.0058 0.0199 0.0505
Trypanosoma cruzi PAB1-binding protein , putative 0.005 0.0166 0.0282
Entamoeba histolytica cysteine protease, putative 0.0039 0.0116 0.1718
Schistosoma mansoni chromobox protein 0.0034 0.0089 0.0226
Plasmodium falciparum heterochromatin protein 1 0.0034 0.0089 0.1165
Loa Loa (eye worm) latrophilin receptor protein 2 0.0017 0.0012 0.0056
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.0018 0.0021 0.0072
Echinococcus granulosus cathepsin L 0.0018 0.0018 0.0047
Brugia malayi Papain family cysteine protease containing protein 0.0018 0.0018 0.01
Loa Loa (eye worm) hypothetical protein 0.0032 0.0082 0.0388
Trypanosoma cruzi mitogen activated protein kinase 2, putative 0.0049 0.0161 0.0274
Echinococcus granulosus FKBP12 rapamycin complex associated protein 0.0044 0.0135 0.0342
Leishmania major vacuolar-type Ca2 -ATPase, putative 0.0076 0.0282 0.3921
Brugia malayi ATP-dependent DNA helicase, RecQ family protein 0.0018 0.0021 0.0112
Giardia lamblia NADH oxidase lateral transfer candidate 0.0053 0.0175 0.0756
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0055 0.0188 0.1881
Entamoeba histolytica cysteine proteinase, putative 0.0039 0.0116 0.1718
Trichomonas vaginalis cAMP-specific 3,5-cyclic phosphodiesterase, putative 0.0058 0.0199 0.1998
Trypanosoma brucei cAMP phosphodiesterase A, putative 0.0058 0.0199 0.2758
Plasmodium falciparum thioredoxin reductase 0.0152 0.0625 1
Trichomonas vaginalis rod cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0058 0.0199 0.1998
Schistosoma mansoni chromodomain helicase DNA binding protein 0.0035 0.0096 0.0244
Toxoplasma gondii 'chromo' (CHRromatin Organization MOdifier) domain-containing protein 0.0034 0.0089 0.0319
Loa Loa (eye worm) RecQ helicase 0.0045 0.014 0.0666
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0055 0.0188 0.1881
Brugia malayi dihydrolipoyl dehydrogenase, mitochondrial precursor, putative 0.0053 0.0175 0.0958
Giardia lamblia Hypothetical protein 0.0058 0.0199 0.0871
Echinococcus multilocularis dna polymerase kappa 0.0142 0.0582 0.1476
Onchocerca volvulus Heterochromatin protein 1 homolog 0.0088 0.0337 0.3297
Entamoeba histolytica cysteine proteinase 2 0.0039 0.0116 0.1718
Loa Loa (eye worm) hypothetical protein 0.023 0.0979 0.4678
Brugia malayi cathepsin Z-like cysteine proteinase 0.0018 0.0018 0.01
Leishmania major calcium motive p-type ATPase, putative 0.0053 0.0177 0.2441
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0055 0.0188 0.1881
Leishmania major calcium-transporting ATPase, putative 0.0053 0.0177 0.2441
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0049 0.0161 0.0274
Loa Loa (eye worm) hypothetical protein 0.0034 0.009 0.0427
Brugia malayi Cathepsin L-like precursor 0.0034 0.009 0.0491
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0475 0.2093 0.7546
Echinococcus multilocularis cathepsin l cysteine peptidase 0.0055 0.0188 0.0476
Loa Loa (eye worm) hypothetical protein 0.0121 0.0486 0.232
Trichomonas vaginalis conserved hypothetical protein 0.0034 0.0089 0.0877
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0055 0.0188 0.1881
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0053 0.0175 0.2423
Echinococcus multilocularis microtubule associated protein 2 0.067 0.298 0.7554
Echinococcus multilocularis calcium:calmodulin dependent 3',5' cyclic 0.0058 0.0199 0.0505
Mycobacterium ulcerans metal cation transporter p-type ATPase a 0.0066 0.0236 0.023
Mycobacterium tuberculosis holo-[acyl-carrier protein] synthase AcpS (holo-ACP synthase) (CoA:APO-[ACP]pantetheinephosphotransferase) (CoA:APO-[acyl-carrie 0.0023 0.004 0.0012
Giardia lamblia Sgs1 DNA helicase, putative 0.0018 0.0021 0.0011
Mycobacterium leprae conserved hypothetical protein 0.0023 0.004 0.0012
Echinococcus multilocularis lipoxygenase domain containing protein 0.0019 0.0024 0.006
Loa Loa (eye worm) CYP4Cod1 0.0015 0.0006 0.0028
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0018 0.0018 0.0047
Giardia lamblia Myb 1-like protein 0.0061 0.0213 0.0937
Schistosoma mansoni alpha-galactosidase/alpha-n-acetylgalactosaminidase 0.0099 0.0388 0.0984
Toxoplasma gondii heavy metal translocating P-type ATPase subfamily protein 0.0021 0.0031 0.0111
Schistosoma mansoni intermediate filament proteins 0.0033 0.0085 0.0214
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0058 0.0199 0.0716
Loa Loa (eye worm) ctsf protein 0.0055 0.0188 0.0894
Loa Loa (eye worm) glycosyl hydrolase family 31 protein 0.0158 0.0655 0.3128
Loa Loa (eye worm) cytochrome P450 family protein 0.0015 0.0006 0.0028
Brugia malayi MH2 domain containing protein 0.0386 0.169 0.9235
Echinococcus granulosus tumor protein p63 0.0328 0.1427 0.3617
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0035 0.0096 0.0948
Echinococcus multilocularis tar DNA binding protein 0.0067 0.0241 0.061
Entamoeba histolytica Niemann-Pick C1 protein, putative 0.0096 0.0371 0.6124
Trichomonas vaginalis DNA helicase recq, putative 0.0024 0.0045 0.043
Echinococcus granulosus nuclear factor of activated T cells 5 0.0071 0.0261 0.0663
Brugia malayi 3'5'-cyclic nucleotide phosphodiesterase family protein 0.0058 0.0199 0.1088
Toxoplasma gondii 'chromo' (CHRromatin Organization MOdifier) domain-containing protein 0.0034 0.0089 0.0319
Trypanosoma cruzi cytochrome P450, putative 0.0015 0.0006 0.0006
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.004 0.0118 0.117
Entamoeba histolytica hypothetical protein 0.0145 0.0595 1
Mycobacterium ulcerans dihydrolipoamide dehydrogenase 0.0053 0.0175 0.0169
Mycobacterium tuberculosis Probable NADH dehydrogenase Ndh 0.0346 0.1508 0.207
Schistosoma mansoni alpha-galactosidase/alpha-n-acetylgalactosaminidase 0.0066 0.0238 0.0603
Plasmodium falciparum cGMP-specific phosphodiesterase 0.0058 0.0199 0.2977
Echinococcus granulosus cathepsin l1 0.0055 0.0188 0.0476
Trypanosoma brucei DNA polymerase kappa, putative 0.0142 0.0582 0.8149
Entamoeba histolytica cysteine protease, putative 0.0039 0.0116 0.1718
Toxoplasma gondii P-type ATPase4, putative 0.0066 0.0236 0.0851
Trypanosoma brucei FAT domain/Rapamycin binding domain/Phosphatidylinositol 3- and 4-kinase, putative 0.0018 0.0019 0.0223
Echinococcus granulosus Ankyrin repeat domain containing protein 0.0087 0.0333 0.0844
Echinococcus granulosus ATP dependent DNA helicase Q5 0.0018 0.0021 0.0052
Trypanosoma brucei unspecified product 0.008 0.0301 0.4192
Brugia malayi Pre-SET motif family protein 0.003 0.0071 0.0388
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0034 0.0089 0.0877
Echinococcus multilocularis cathepsin l cysteine peptidase 0.0055 0.0188 0.0476
Trichomonas vaginalis PIKK family atypical protein kinase 0.0032 0.0084 0.0825
Trypanosoma brucei dihydrolipoamide dehydrogenase, point mutation 0.0053 0.0175 0.2423
Echinococcus granulosus GPCR family 2 0.0017 0.0012 0.0031
Echinococcus granulosus calcium transporting ATPase type 2C member 0.0089 0.0341 0.0866
Loa Loa (eye worm) blistered cuticle protein 3 0.0026 0.0053 0.0252
Mycobacterium ulcerans hypothetical protein 0.0036 0.0101 0.0094
Echinococcus granulosus lipoxygenase domain containing protein 0.0019 0.0024 0.006
Loa Loa (eye worm) hypothetical protein 0.0026 0.0053 0.0252
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0055 0.0188 0.1881
Schistosoma mansoni camp-specific 35-cyclic phosphodiesterase 0.0058 0.0199 0.0505
Trypanosoma cruzi hypothetical protein, conserved 0.0036 0.0101 0.0169
Echinococcus granulosus microtubule associated protein 2 0.067 0.298 0.7554
Echinococcus multilocularis Niemann Pick C1 protein 0.0137 0.0557 0.1412
Trypanosoma cruzi cAMP phosphodiesterase A, putative 0.0058 0.0199 0.034
Schistosoma mansoni alpha-glucosidase 0.0136 0.0555 0.1407
Onchocerca volvulus 0.0231 0.0984 1
Toxoplasma gondii cathepsin CPC2 0.0018 0.0018 0.0064
Echinococcus multilocularis neuropeptide receptor A26 0.0455 0.2004 0.508
Trichomonas vaginalis calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative 0.0058 0.0199 0.1998
Trichomonas vaginalis chromobox protein, putative 0.0034 0.0089 0.0877
Echinococcus multilocularis musashi 0.0033 0.0085 0.0214
Brugia malayi Intermediate filament tail domain containing protein 0.0033 0.0085 0.0462
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0055 0.0188 0.1881
Mycobacterium ulcerans DNA polymerase IV 0.0142 0.0582 0.0576
Loa Loa (eye worm) cytochrome P450 family protein 0.0015 0.0006 0.0028
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.003 0.0072 0.026
Schistosoma mansoni high-affinity cgmp-specific 35-cyclic phosphodiesterase 0.0058 0.0199 0.0505
Trichomonas vaginalis MYB3r3, putative 0.0061 0.0211 0.2125
Brugia malayi Pre-SET motif family protein 0.0203 0.0857 0.4682
Trichomonas vaginalis r2r3-MYB transcription factor, putative 0.0061 0.0213 0.2138
Trichomonas vaginalis chromobox protein, putative 0.0094 0.0363 0.3675
Loa Loa (eye worm) hypothetical protein 0.006 0.0211 0.1006
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0147 0.0603 0.8436
Loa Loa (eye worm) hypothetical protein 0.0055 0.0188 0.0894
Schistosoma mansoni smad1 5 8 and 0.0026 0.0056 0.0142
Trypanosoma brucei DNA polymerase kappa, putative 0.0142 0.0582 0.8149
Loa Loa (eye worm) hypothetical protein 0.0016 0.0008 0.0036
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.0047 0.0149 0.0816
Brugia malayi Probable 3',5'-cyclic phosphodiesterase T04D3.3, putative 0.0058 0.0199 0.1088
Schistosoma mansoni peroxidasin 0.0026 0.0053 0.0135
Echinococcus granulosus cathepsin L cysteine proteinase 0.0055 0.0188 0.0476
Schistosoma mansoni cathepsin B (C01 family) 0.0018 0.0018 0.0047
Leishmania major ATP-dependent DEAD/H DNA helicase recQ, putative 0.0024 0.0045 0.0594
Entamoeba histolytica hypothetical protein 0.0145 0.0595 1
Trypanosoma brucei cAMP-specific phosphodiesterase 0.0058 0.0199 0.2758
Echinococcus multilocularis thioredoxin glutathione reductase 0.0152 0.0625 0.1585
Loa Loa (eye worm) RNA binding protein 0.0067 0.0241 0.1147
Mycobacterium ulcerans cation-transporter ATPase I CtpI 0.0045 0.014 0.0134
Trichomonas vaginalis plasma membrane calcium-transporting ATPase, putative 0.0076 0.0282 0.2841
Trichomonas vaginalis r2r3-MYB transcription factor, putative 0.0061 0.0211 0.2125
Plasmodium falciparum cysteine proteinase falcipain 2b 0.0055 0.0188 0.2788
Trichomonas vaginalis ATPase, class VI, type 11C, putative 0.0021 0.0031 0.0287
Loa Loa (eye worm) heterochromatin protein 1 0.0149 0.0611 0.2919
Schistosoma mansoni type V p-type atpase isoform 0.0021 0.0031 0.0079
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0055 0.0188 0.1881
Trypanosoma cruzi DNA polymerase kappa, putative 0.0142 0.0582 0.1004
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0018 0.0018 0.0156
Trypanosoma cruzi cAMP-specific phosphodiesterase, putative 0.0058 0.0199 0.034
Schistosoma mansoni multiple ankyrin repeats single kh domain protein 0.0087 0.0333 0.0844
Schistosoma mansoni hypothetical protein 0.0036 0.01 0.0254
Echinococcus granulosus dna polymerase kappa 0.0142 0.0582 0.1476
Trichomonas vaginalis alpha-galactosidase/alpha-N-acetylgalactosaminidase, putative 0.0066 0.0238 0.2393
Schistosoma mansoni lipoxygenase 0.0019 0.0024 0.006
Entamoeba histolytica chromodomain-helicase-DNA-binding protein, putative 0.0034 0.0089 0.1253
Schistosoma mansoni hypothetical protein 0.0397 0.174 0.4412
Echinococcus granulosus Niemann Pick C1 protein 0.0096 0.0371 0.094
Schistosoma mansoni alpha-galactosidase/alpha-n-acetylgalactosaminidase 0.0014 0.0001 0.0001
Toxoplasma gondii P-type ATPase PMA1 0.0042 0.0127 0.0457
Onchocerca volvulus Cathepsin L homolog 0.0055 0.0188 0.1752
Trichomonas vaginalis conserved hypothetical protein 0.0034 0.0089 0.0877
Loa Loa (eye worm) hypothetical protein 0.0021 0.0034 0.0161
Trypanosoma brucei DNA polymerase kappa, putative 0.0142 0.0582 0.8149
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0147 0.0603 0.8436
Giardia lamblia Plasma membrane calcium-transporting ATPase 2 0.0076 0.0282 0.1269
Echinococcus granulosus sarco:endoplasmic reticulum calcium ATPase 0.0089 0.0341 0.0866
Echinococcus granulosus cpg binding protein 0.0029 0.007 0.0179
Onchocerca volvulus 0.0047 0.0149 0.1355
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0037 0.0104 0.1034
Schistosoma mansoni cathepsin s 0.0021 0.0034 0.0087
Trypanosoma cruzi hypothetical protein, conserved 0.0036 0.0101 0.0169
Loa Loa (eye worm) cytoplasmic intermediate filament protein 0.0017 0.0016 0.0073
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0055 0.0188 0.1881
Trichomonas vaginalis alpha-glucosidase, putative 0.0035 0.0096 0.0948
Trypanosoma cruzi cysteine peptidase (N-terminal), putative 0.0039 0.0116 0.0196
Trypanosoma brucei DNA polymerase kappa, putative 0.0087 0.033 0.4601
Brugia malayi Animal haem peroxidase family protein 0.0026 0.0053 0.0291
Trichomonas vaginalis high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0058 0.0199 0.1998
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0017 0.0012 0.0031
Schistosoma mansoni mixed-lineage leukemia protein mll 0.006 0.021 0.0533
Entamoeba histolytica phosphatidylinositol3-kinaseTor2, putative 0.0044 0.0135 0.2043
Echinococcus granulosus dual 3'5' cyclic AMP and GMP phosphodiesterase 0.0058 0.0199 0.0505
Plasmodium falciparum ATP-dependent DNA helicase Q1 0.0018 0.0021 0.0036
Leishmania major cathepsin L-like protease 0.0055 0.0188 0.2597
Loa Loa (eye worm) abnormal chemotaxis protein 14 0.0041 0.0123 0.0585
Schistosoma mansoni chromobox protein-related (chromobox 1) (heterochromatin 1) 0.0034 0.0089 0.0226
Trypanosoma brucei cation-transporting ATPase, putative 0.0021 0.0031 0.0396
Onchocerca volvulus 0.0091 0.0352 0.3455
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0055 0.0188 0.1881
Schistosoma mansoni plasma membrane calcium-transporting atpase 0.0063 0.0222 0.0562
Entamoeba histolytica cysteine protease, putative 0.0039 0.0116 0.1718
Trichomonas vaginalis high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0058 0.0199 0.1998
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.004 0.0118 0.117
Trichomonas vaginalis conserved hypothetical protein 0.0058 0.0199 0.1998
Loa Loa (eye worm) hypothetical protein 0.005 0.0166 0.0789
Brugia malayi E1-E2 ATPase family protein 0.0042 0.0127 0.0696
Brugia malayi Latrophilin receptor protein 2 0.0017 0.0012 0.0067
Echinococcus multilocularis mothers against decapentaplegic 5 0.0026 0.0056 0.0142
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.004 0.0118 0.117
Trypanosoma cruzi mitogen activated protein kinase 4, putative 0.0049 0.0161 0.0274
Echinococcus multilocularis copper transporting ATPase 1 0.0021 0.0031 0.0079
Echinococcus granulosus cAMP and cAMP inhibited cGMP 3'5' cyclic 0.0058 0.0199 0.0505
Schistosoma mansoni hypothetical protein 0.004 0.0116 0.0295
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0053 0.0175 0.0298
Schistosoma mansoni SmCB2 peptidase (C01 family) 0.0018 0.0018 0.0047
Onchocerca volvulus Huntingtin homolog 0.0119 0.0477 0.4746
Onchocerca volvulus 0.0055 0.0188 0.1752
Trypanosoma brucei copper-transporting ATPase-like protein, putative 0.0021 0.0031 0.0396
Echinococcus granulosus chromobox protein 2 0.0034 0.0089 0.0226
Echinococcus multilocularis Ankyrin 0.0014 0.0001 0.0001
Echinococcus multilocularis TGF beta signal transducer SmadC 0.0026 0.0056 0.0142
Plasmodium vivax vivapain-3 0.0039 0.0116 0.1608
Trypanosoma brucei hypothetical protein, conserved 0.0036 0.0101 0.1372
Toxoplasma gondii thioredoxin reductase 0.0152 0.0625 0.2253
Echinococcus multilocularis smad 0.0026 0.0056 0.0142
Onchocerca volvulus 0.0081 0.0303 0.2949
Trichomonas vaginalis conserved hypothetical protein 0.0018 0.0018 0.0156
Loa Loa (eye worm) RNA recognition domain-containing protein domain-containing protein 0.0067 0.0241 0.1147
Echinococcus granulosus calcium:calmodulin dependent 3'5' cyclic 0.0058 0.0199 0.0505
Brugia malayi Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain containing protein 0.0039 0.0112 0.0611
Entamoeba histolytica cysteine protease, putative 0.0018 0.0018 0.003
Trichomonas vaginalis cGMP-dependent 3,5-cyclic phosphodiesterase, putative 0.0058 0.0199 0.1998
Trichomonas vaginalis calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase, putative 0.0058 0.0199 0.1998
Entamoeba histolytica calcium-transporting P-type ATPase, putative 0.0066 0.0236 0.3801
Echinococcus granulosus neuropeptide s receptor 0.0455 0.2004 0.508
Trichomonas vaginalis r2r3-MYB transcription factor, putative 0.0061 0.0211 0.2125
Trichomonas vaginalis r2r3-MYB transcription factor, putative 0.0061 0.0213 0.2138
Echinococcus granulosus neutral alpha glucosidase AB 0.0035 0.0096 0.0243
Trypanosoma brucei unspecified product 0.008 0.0301 0.4192
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0055 0.0188 0.1881
Schistosoma mansoni cation-transporting atpase worm 0.0021 0.0031 0.0079
Toxoplasma gondii ImpB/MucB/SamB family protein 0.0091 0.0349 0.1258
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0055 0.0188 0.1881
Brugia malayi Associated with TFs and helicases family protein 0.0034 0.0089 0.0487
Mycobacterium leprae PROBABLE NADH DEHYDROGENASE NDH 0.0346 0.1508 0.207
Echinococcus multilocularis lamin 0.0033 0.0085 0.0214
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0203 0.0857 0.4094
Trypanosoma cruzi P-type H+-ATPase, putative 0.0029 0.0068 0.0112
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0049 0.0161 0.0274
Trypanosoma brucei phosphatidylinositol 3-kinase tor, putative 0.0021 0.003 0.0384
Trichomonas vaginalis Clan CA, family C1, cathepsin F-like cysteine peptidase 0.0018 0.0018 0.0156
Brugia malayi ImpB/MucB/SamB family protein 0.0116 0.0465 0.254
Echinococcus granulosus cathepsin b 0.0018 0.0018 0.0047
Trichomonas vaginalis PIKK family atypical protein kinase 0.0026 0.0054 0.0518
Trichomonas vaginalis calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative 0.0058 0.0199 0.1998
Trichomonas vaginalis cAMP-specific phosphodiesterase, putative 0.0058 0.0199 0.1998
Plasmodium vivax copper-transporting ATPase, putative 0.0021 0.0031 0.0212
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0058 0.0199 0.0716
Plasmodium falciparum phosphodiesterase delta, putative 0.0058 0.0199 0.2977
Trichomonas vaginalis calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative 0.0058 0.0199 0.1998
Trypanosoma cruzi cAMP specific phosphodiesterase, putative 0.0058 0.0199 0.034
Entamoeba histolytica Plasma membrane calcium-transporting ATPase, putative 0.0076 0.0282 0.4584
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0044 0.0135 0.0736
Trichomonas vaginalis plasma membrane calcium-transporting ATPase, putative 0.0076 0.0282 0.2841
Loa Loa (eye worm) TAR-binding protein 0.0067 0.0241 0.1147
Trypanosoma cruzi cysteine protease, putative 0.0039 0.0116 0.0196
Trichomonas vaginalis cAMP-specific phosphodiesterase, putative 0.0058 0.0199 0.1998
Loa Loa (eye worm) hypothetical protein 0.0138 0.0562 0.2682
Echinococcus granulosus cathepsin l cysteine peptidase 0.0055 0.0188 0.0476
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0018 0.0018 0.0085
Schistosoma mansoni chromobox protein-related (chromobox 1) (heterochromatin 1) 0.0034 0.0089 0.0226
Trichomonas vaginalis PIKK family atypical protein kinase 0.0035 0.0094 0.0929
Loa Loa (eye worm) hypothetical protein 0.0026 0.0053 0.0252
Trypanosoma brucei chrX additional, unordered contigs 0.0036 0.0101 0.1372
Trypanosoma brucei vacuolar-type Ca2+-ATPase, putative 0.0076 0.0282 0.3921
Mycobacterium tuberculosis Probable membrane NADH dehydrogenase NdhA 0.0346 0.1508 0.207
Schistosoma mansoni hypothetical protein 0.004 0.0116 0.0295
Trichomonas vaginalis PIKK family atypical protein kinase 0.0024 0.0044 0.0413
Echinococcus granulosus cathepsin b 0.0018 0.0018 0.0047
Leishmania major DNA polymerase kappa, putative,DNA polymerase IV, putative 0.0123 0.0494 0.6908
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0053 0.0175 0.0298
Echinococcus multilocularis ATP dependent DNA helicase Q1 0.0018 0.0021 0.0052
Echinococcus multilocularis cathepsin L 0.0018 0.0018 0.0047
Loa Loa (eye worm) hypothetical protein 0.0015 0.0005 0.0023
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0053 0.0175 0.0298
Giardia lamblia Potassium-transporting ATPase alpha chain 1 0.0053 0.0177 0.0762
Echinococcus granulosus survival motor neuron protein 1 0.023 0.0979 0.2483
Mycobacterium ulcerans cation transporter p-type ATPase D CtpD 0.0021 0.0031 0.0025
Echinococcus multilocularis dual 3',5' cyclic AMP and GMP phosphodiesterase 0.0058 0.0199 0.0505
Entamoeba histolytica myb-like DNA-binding domain containing protein 0.0061 0.0211 0.3369
Echinococcus multilocularis cAMP and cAMP inhibited cGMP 3',5' cyclic 0.0058 0.0199 0.0505
Trypanosoma brucei calcium motive p-type ATPase, putative 0.0053 0.0177 0.2441
Brugia malayi MH1 domain containing protein 0.0026 0.0056 0.0306
Leishmania major mitogen activated protein kinase 4, putative;with=GeneDB:LmxM19.1440 0.0049 0.0161 0.2227
Trypanosoma cruzi cysteine peptidase, putative 0.1285 0.5774 1
Trichomonas vaginalis MYB, putative 0.0061 0.0213 0.2138
Brugia malayi chromobox protein homolog 3 0.0088 0.0337 0.1841
Trypanosoma brucei P-type H+-ATPase, putative 0.0042 0.0127 0.1749
Onchocerca volvulus 0.0019 0.0024 0.0054
Trichomonas vaginalis calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative 0.0058 0.0199 0.1998
Leishmania major DNA polymerase kappa, putative 0.0123 0.0494 0.6908
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0018 0.0018 0.0156
Brugia malayi Papain family cysteine protease containing protein 0.0055 0.0188 0.1025
Mycobacterium tuberculosis Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB 0.0346 0.1508 0.207
Brugia malayi Bloom's syndrome protein homolog 0.0045 0.014 0.0765
Trypanosoma cruzi target of rapamycin kinase 3 0.0035 0.0094 0.0158
Schistosoma mansoni alpha-galactosidase/alpha-n-acetylgalactosaminidase 0.0066 0.0238 0.0603
Schistosoma mansoni calcium/calmodulin-dependent 35-cyclic nucleotide phosphodiesterase 0.0058 0.0199 0.0505
Entamoeba histolytica cysteine protease, putative 0.0039 0.0116 0.1718
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0053 0.0175 0.0298
Brugia malayi MH1 domain containing protein 0.0026 0.0056 0.0306
Trypanosoma cruzi P-type H+-ATPase, putative 0.0042 0.0127 0.0215
Loa Loa (eye worm) hypothetical protein 0.0026 0.0053 0.0252
Brugia malayi MH2 domain containing protein 0.0026 0.0056 0.0306
Echinococcus multilocularis FKBP12 rapamycin complex associated protein 0.0044 0.0135 0.0342
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0147 0.0603 0.8436
Entamoeba histolytica cysteine protease, putative 0.0018 0.0018 0.003
Loa Loa (eye worm) hypothetical protein 0.0018 0.0018 0.0085
Plasmodium vivax thioredoxin reductase, putative 0.0152 0.0625 1
Brugia malayi Cytochrome P450 family protein 0.0015 0.0006 0.0035
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0053 0.0175 0.2423
Toxoplasma gondii E1-E2 ATPase subfamily protein 0.0029 0.0068 0.0242
Leishmania major target of rapamycin (TOR) kinase 2, putative 0.0044 0.0135 0.1853
Mycobacterium ulcerans UDP-N-acetylglucosamine 1-carboxyvinyltransferase 0.2215 1 1
Brugia malayi TAR-binding protein 0.0067 0.0241 0.1315
Plasmodium falciparum LCCL domain-containing protein 0.0019 0.0024 0.0086
Echinococcus multilocularis dnaJ subfamily B 0.0397 0.174 0.4412
Trichomonas vaginalis chromobox protein, putative 0.0149 0.0611 0.6201
Schistosoma mansoni cathepsin F (C01 family) 0.0055 0.0188 0.0476
Trichomonas vaginalis cAMP and cAMP-inhibited cGMP 3,5-cyclic phosphodiesterase, putative 0.0058 0.0199 0.1998
Schistosoma mansoni cation-transporting atpase worm 0.0021 0.0031 0.0079
Onchocerca volvulus 0.0048 0.0155 0.1411
Echinococcus multilocularis protein patched 0.0041 0.0123 0.0312
Trichomonas vaginalis cyclic nucleotide phosphodiesterase, putative 0.0058 0.0199 0.1998
Schistosoma mansoni smad1 5 8 and 0.0026 0.0056 0.0142
Schistosoma mansoni rab geranylgeranyl transferase alpha subunit 0.0116 0.0465 0.1179
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.004 0.0118 0.117
Echinococcus granulosus ATP dependent DNA helicase Q1 0.0018 0.0021 0.0052
Brugia malayi potential phospholipid-transporting ATPase IIB, putative 0.0021 0.0031 0.0171
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.0018 0.0021 0.0072
Leishmania major P-type H -ATPase, putative 0.0042 0.0127 0.1749
Trichomonas vaginalis PIKK family atypical protein kinase 0.0026 0.0055 0.053
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.0055 0.0188 0.1881
Schistosoma mansoni polycystin 1-related 0.0019 0.0024 0.006
Loa Loa (eye worm) MH1 domain-containing protein 0.0026 0.0056 0.0266
Loa Loa (eye worm) cysteine proteinase cathepsin Z 0.0018 0.0018 0.0085
Loa Loa (eye worm) hypothetical protein 0.005 0.0165 0.0785
Onchocerca volvulus 0.0019 0.0024 0.0054
Trichomonas vaginalis cyclic nucleotide phosphodiesterase, putative 0.0058 0.0199 0.1998
Trichomonas vaginalis mercuric reductase, putative 0.0053 0.0175 0.1756
Echinococcus granulosus calcium transporting atpase 0.0076 0.0282 0.0714

Activities

Activity type Activity value Assay description Source Reference
Potency (functional) = 0.0282 um PUBCHEM_BIOASSAY: qHTS Assay for Modulators of Lamin A Splicing. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) 29.0929 uM PubChem BioAssay. A quantitative high throughput screen for small molecules that induce DNA re-replication in SW480 colon adenocarcinoma cells. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) = 35.4813 um PUBCHEM_BIOASSAY: qHTS Assay for Inhibitors of Aldehyde Dehydrogenase 1 (ALDH1A1). (Class of assay: confirmatory) [Related pubchem assays: 1030 (qHTS Validation Assay for Inhibitors of aldehyde dehydrogenase 1 (ALDH1A1))] ChEMBL. No reference

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

No literature references available for this target.

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