Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Loa Loa (eye worm) | hypothetical protein | 0.0071 | 0.0419 | 0.0675 |
Echinococcus granulosus | histone lysine methyltransferase setb | 0.0076 | 0.0454 | 0.0454 |
Brugia malayi | MH1 domain containing protein | 0.0058 | 0.0319 | 0.0514 |
Loa Loa (eye worm) | PHD-finger family protein | 0.0029 | 0.0108 | 0.0174 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0033 | 0.0136 | 0.0406 |
Schistosoma mansoni | cellular tumor antigen P53 | 0.0149 | 0.1003 | 0.1003 |
Loa Loa (eye worm) | hypothetical protein | 0.0141 | 0.0937 | 0.151 |
Echinococcus multilocularis | TGF beta signal transducer SmadC | 0.0058 | 0.0319 | 0.0319 |
Schistosoma mansoni | lamin | 0.0027 | 0.0089 | 0.0089 |
Trichomonas vaginalis | D-aminoacylase, putative | 0.0141 | 0.0937 | 0.2793 |
Loa Loa (eye worm) | hypothetical protein | 0.0048 | 0.0248 | 0.0399 |
Echinococcus granulosus | fetal alzheimer antigen falz | 0.0023 | 0.0058 | 0.0058 |
Trichomonas vaginalis | D-aminoacylase, putative | 0.0141 | 0.0937 | 0.2793 |
Onchocerca volvulus | 0.0027 | 0.0089 | 0.0027 | |
Echinococcus multilocularis | expressed protein | 0.0026 | 0.0085 | 0.0085 |
Schistosoma mansoni | ferritin | 0.0026 | 0.0085 | 0.0085 |
Echinococcus granulosus | Basic leucine zipper bZIP transcription | 0.0146 | 0.0975 | 0.0975 |
Echinococcus granulosus | diuretic hormone 44 receptor GPRdih2 | 0.0033 | 0.0134 | 0.0134 |
Echinococcus granulosus | 5'partial|histone lysine N methyltransferase SETDB2 | 0.0056 | 0.0309 | 0.0309 |
Schistosoma mansoni | smad1 5 8 and | 0.0058 | 0.0319 | 0.0319 |
Echinococcus multilocularis | thyroid hormone receptor alpha | 0.0133 | 0.0878 | 0.0878 |
Echinococcus multilocularis | histone lysine N methyltransferase SETMAR | 0.0059 | 0.0325 | 0.0325 |
Schistosoma mansoni | family S12 unassigned peptidase (S12 family) | 0.0141 | 0.0937 | 0.0937 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0045 | 0.0222 | 0.066 |
Brugia malayi | Bromodomain containing protein | 0.0039 | 0.0179 | 0.0288 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0033 | 0.0136 | 0.0406 |
Echinococcus multilocularis | lamin | 0.0027 | 0.0089 | 0.0089 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0045 | 0.0227 | 0.0227 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0141 | 0.0937 | 1 |
Onchocerca volvulus | 0.0141 | 0.0937 | 0.2616 | |
Trichomonas vaginalis | D-aminoacylase, putative | 0.0141 | 0.0937 | 0.2793 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0045 | 0.0227 | 0.0227 |
Brugia malayi | TAR-binding protein | 0.0394 | 0.2831 | 0.4559 |
Loa Loa (eye worm) | acetyltransferase | 0.029 | 0.2055 | 0.3309 |
Echinococcus multilocularis | FKBP12 rapamycin complex associated protein | 0.0045 | 0.0222 | 0.0222 |
Brugia malayi | MH1 domain containing protein | 0.0032 | 0.0126 | 0.0204 |
Schistosoma mansoni | smad1 5 8 and | 0.0058 | 0.0319 | 0.0319 |
Loa Loa (eye worm) | hypothetical protein | 0.005 | 0.0262 | 0.0423 |
Brugia malayi | Phosphatidylinositol 3- and 4-kinase family protein | 0.0045 | 0.0222 | 0.0357 |
Trypanosoma brucei | hypothetical protein, conserved | 0.0141 | 0.0937 | 1 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0024 | 0.0068 | 0.0203 |
Brugia malayi | Latrophilin receptor protein 2 | 0.0033 | 0.0134 | 0.0216 |
Loa Loa (eye worm) | intermediate filament protein | 0.0027 | 0.0089 | 0.0144 |
Echinococcus granulosus | intermediate filament protein | 0.0027 | 0.0089 | 0.0089 |
Schistosoma mansoni | smad | 0.0026 | 0.0081 | 0.0081 |
Leishmania major | hypothetical protein, conserved | 0.0141 | 0.0937 | 1 |
Echinococcus granulosus | PHD finger protein rhinoceros | 0.0029 | 0.0108 | 0.0108 |
Echinococcus granulosus | lysine specific demethylase 5A | 0.0038 | 0.0169 | 0.0169 |
Echinococcus granulosus | bromodomain adjacent to zinc finger domain | 0.0067 | 0.0391 | 0.0391 |
Echinococcus granulosus | histone acetyltransferase KAT2B | 0.0087 | 0.0538 | 0.0538 |
Schistosoma mansoni | intermediate filament proteins | 0.0027 | 0.0089 | 0.0089 |
Echinococcus granulosus | Mitotic checkpoint protein PRCC C terminal | 0.0123 | 0.0804 | 0.0804 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0027 | 0.0087 | 0.026 |
Echinococcus granulosus | GPCR family 2 | 0.0033 | 0.0134 | 0.0134 |
Echinococcus granulosus | tumor protein p63 | 0.1021 | 0.7508 | 0.7508 |
Brugia malayi | MH2 domain containing protein | 0.0847 | 0.6209 | 1 |
Echinococcus granulosus | bromodomain adjacent to zinc finger domain | 0.0036 | 0.0159 | 0.0159 |
Echinococcus granulosus | cadherin EGF LAG seven pass G type receptor | 0.0033 | 0.0134 | 0.0134 |
Echinococcus multilocularis | ferritin | 0.0026 | 0.0085 | 0.0085 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0036 | 0.0153 | 0.0457 |
Echinococcus granulosus | methyl CpG binding domain protein 2 | 0.0017 | 0.0017 | 0.0017 |
Schistosoma mansoni | methyl-cpg binding protein mbd | 0.0017 | 0.0017 | 0.0017 |
Trypanosoma brucei | phosphatidylinositol 4-kinase, putative | 0.0045 | 0.0222 | 0.2364 |
Trypanosoma brucei | target of rapamycin kinase 3, putative | 0.0036 | 0.0154 | 0.1639 |
Echinococcus multilocularis | jumonji domain containing protein | 0.0041 | 0.0194 | 0.0194 |
Mycobacterium ulcerans | lipase LipD | 0.0141 | 0.0937 | 1 |
Plasmodium falciparum | histone acetyltransferase GCN5 | 0.0078 | 0.0467 | 1 |
Echinococcus granulosus | lamin dm0 | 0.0027 | 0.0089 | 0.0089 |
Schistosoma mansoni | Smad4 | 0.0058 | 0.0319 | 0.0319 |
Schistosoma mansoni | smad | 0.0058 | 0.0319 | 0.0319 |
Loa Loa (eye worm) | RNA binding protein | 0.0394 | 0.2831 | 0.4559 |
Schistosoma mansoni | lamin | 0.0027 | 0.0089 | 0.0089 |
Echinococcus multilocularis | bromodomain adjacent to zinc finger domain | 0.0036 | 0.0159 | 0.0159 |
Schistosoma mansoni | bromodomain containing protein | 0.0071 | 0.0418 | 0.0418 |
Loa Loa (eye worm) | hypothetical protein | 0.0071 | 0.0421 | 0.0679 |
Echinococcus multilocularis | mothers against decapentaplegic 6 | 0.0026 | 0.0081 | 0.0081 |
Echinococcus multilocularis | zinc finger protein | 0.0027 | 0.0088 | 0.0088 |
Echinococcus multilocularis | gcn5proteinral control of amino acid synthesis | 0.029 | 0.2055 | 0.2055 |
Schistosoma mansoni | acetyl-CoA C-acetyltransferase | 0.0023 | 0.0058 | 0.0058 |
Schistosoma mansoni | histone-lysine n-methyltransferase suv9 | 0.0059 | 0.0325 | 0.0325 |
Treponema pallidum | bacterioferrin (TpF1) | 0.0026 | 0.0085 | 0.5 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0027 | 0.0087 | 0.026 |
Echinococcus multilocularis | GPCR, family 2 | 0.0033 | 0.0134 | 0.0134 |
Brugia malayi | jmjC domain containing protein | 0.0097 | 0.0609 | 0.0981 |
Brugia malayi | Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative | 0.0141 | 0.0937 | 0.151 |
Loa Loa (eye worm) | MH1 domain-containing protein | 0.0026 | 0.0081 | 0.013 |
Echinococcus multilocularis | mothers against decapentaplegic 2 | 0.0026 | 0.0081 | 0.0081 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0036 | 0.0153 | 0.0457 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0024 | 0.0068 | 0.0202 |
Brugia malayi | hypothetical protein | 0.0016 | 0.001 | 0.0015 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0045 | 0.0227 | 0.0227 |
Mycobacterium ulcerans | esterase/lipase LipP | 0.0141 | 0.0937 | 1 |
Trichomonas vaginalis | cat eye syndrome critical region protein 2, cscr2, putative | 0.0087 | 0.0538 | 0.1603 |
Brugia malayi | Calcitonin receptor-like protein seb-1 | 0.0104 | 0.0665 | 0.1071 |
Brugia malayi | GTP-binding regulatory protein Gs alpha-S chain, putative | 0.0045 | 0.0227 | 0.0365 |
Loa Loa (eye worm) | hypothetical protein | 0.0033 | 0.0134 | 0.0216 |
Schistosoma mansoni | hypothetical protein | 0.0146 | 0.0975 | 0.0975 |
Loa Loa (eye worm) | nuclear factor I | 0.0032 | 0.0126 | 0.0204 |
Echinococcus granulosus | mothers against decapentaplegic 5 | 0.0058 | 0.0319 | 0.0319 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0033 | 0.0136 | 0.0406 |
Echinococcus multilocularis | musashi | 0.0027 | 0.0089 | 0.0089 |
Mycobacterium tuberculosis | Probable hydrolase | 0.0141 | 0.0937 | 0.1311 |
Giardia lamblia | GTOR | 0.0045 | 0.0222 | 0.3156 |
Loa Loa (eye worm) | hypothetical protein | 0.0025 | 0.0076 | 0.0123 |
Schistosoma mansoni | tar DNA-binding protein | 0.0394 | 0.2831 | 0.2831 |
Schistosoma mansoni | smad1 5 8 and | 0.0058 | 0.0319 | 0.0319 |
Loa Loa (eye worm) | hypothetical protein | 0.0026 | 0.0081 | 0.013 |
Echinococcus multilocularis | cadherin EGF LAG seven pass G type receptor | 0.0033 | 0.0134 | 0.0134 |
Echinococcus granulosus | tar DNA binding protein | 0.0394 | 0.2831 | 0.2831 |
Trypanosoma cruzi | target of rapamycin kinase 3 | 0.0036 | 0.0154 | 0.1639 |
Schistosoma mansoni | hypothetical protein | 0.0123 | 0.0804 | 0.0804 |
Loa Loa (eye worm) | hypothetical protein | 0.0032 | 0.0126 | 0.0204 |
Trichomonas vaginalis | penicillin-binding protein, putative | 0.0141 | 0.0937 | 0.2793 |
Loa Loa (eye worm) | hypothetical protein | 0.0141 | 0.0937 | 0.151 |
Loa Loa (eye worm) | hypothetical protein | 0.0141 | 0.0937 | 0.151 |
Echinococcus multilocularis | histone lysine methyltransferase setb histone lysine methyltransferase eggless | 0.0076 | 0.0454 | 0.0454 |
Loa Loa (eye worm) | Smad1 | 0.0058 | 0.0319 | 0.0514 |
Brugia malayi | beta-lactamase family protein | 0.0141 | 0.0937 | 0.151 |
Onchocerca volvulus | 0.0059 | 0.0325 | 0.0747 | |
Schistosoma mansoni | jumonji/arid domain-containing protein | 0.0038 | 0.0169 | 0.0169 |
Schistosoma mansoni | bromodomain-containing nuclear protein 1 brd1 | 0.0029 | 0.0108 | 0.0108 |
Leishmania major | target of rapamycin kinase (TOR) kinase 3 | 0.0036 | 0.0154 | 0.1639 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0026 | 0.0085 | 0.0255 |
Echinococcus multilocularis | peregrin | 0.0039 | 0.0179 | 0.0179 |
Loa Loa (eye worm) | RNA recognition domain-containing protein domain-containing protein | 0.0394 | 0.2831 | 0.4559 |
Schistosoma mansoni | hypothetical protein | 0.0033 | 0.0134 | 0.0134 |
Echinococcus multilocularis | fetal alzheimer antigen, falz | 0.0023 | 0.0058 | 0.0058 |
Brugia malayi | MH2 domain containing protein | 0.0026 | 0.0081 | 0.013 |
Onchocerca volvulus | 0.0149 | 0.1003 | 0.2817 | |
Loa Loa (eye worm) | hypothetical protein | 0.0026 | 0.0086 | 0.0138 |
Brugia malayi | beta-lactamase | 0.0141 | 0.0937 | 0.151 |
Entamoeba histolytica | acetyltransferase, GNAT family | 0.0078 | 0.0467 | 0.3261 |
Toxoplasma gondii | ABC1 family protein | 0.0141 | 0.0937 | 1 |
Wolbachia endosymbiont of Brugia malayi | bacterioferritin/cytochrome b1 | 0.0026 | 0.0085 | 0.5 |
Trypanosoma cruzi | PAB1-binding protein , putative | 0.0025 | 0.0076 | 0.0814 |
Brugia malayi | Corticotropin releasing factor receptor 2 precursor, putative | 0.0104 | 0.0665 | 0.1071 |
Plasmodium vivax | hypothetical protein, conserved | 0.0029 | 0.0108 | 0.0371 |
Echinococcus multilocularis | lysine specific demethylase 5A | 0.0036 | 0.0155 | 0.0155 |
Loa Loa (eye worm) | GTP-binding regulatory protein Gs alpha-S chain | 0.0045 | 0.0227 | 0.0365 |
Echinococcus granulosus | jumonji domain containing protein | 0.0041 | 0.0194 | 0.0194 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0036 | 0.0153 | 0.0457 |
Echinococcus granulosus | peregrin | 0.0039 | 0.0179 | 0.0179 |
Brugia malayi | mothers against decapentaplegic homolog 3 | 0.0026 | 0.0081 | 0.013 |
Echinococcus multilocularis | diuretic hormone 44 receptor GPRdih2 | 0.0033 | 0.0134 | 0.0134 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0045 | 0.0222 | 0.066 |
Loa Loa (eye worm) | hypothetical protein | 0.0076 | 0.0454 | 0.0731 |
Toxoplasma gondii | histone lysine acetyltransferase GCN5-B | 0.0087 | 0.0538 | 0.5361 |
Brugia malayi | MH2 domain containing protein | 0.0058 | 0.0319 | 0.0514 |
Brugia malayi | calcium-independent alpha-latrotoxin receptor 2, putative | 0.0033 | 0.0134 | 0.0216 |
Echinococcus multilocularis | Mitotic checkpoint protein PRCC, C terminal | 0.0123 | 0.0804 | 0.0804 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0033 | 0.0136 | 0.0406 |
Schistosoma mansoni | hypothetical protein | 0.0021 | 0.0044 | 0.0044 |
Schistosoma mansoni | jumonji domain containing protein | 0.0077 | 0.0461 | 0.0461 |
Toxoplasma gondii | PHD-finger domain-containing protein | 0.0029 | 0.0108 | 0.0371 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0045 | 0.0227 | 0.0227 |
Trypanosoma cruzi | Phosphatidylinositol 3-kinase tor1 | 0.0045 | 0.0222 | 0.2364 |
Mycobacterium tuberculosis | Probable esterase LipL | 0.0141 | 0.0937 | 0.1311 |
Mycobacterium ulcerans | beta-lactamase | 0.0141 | 0.0937 | 1 |
Entamoeba histolytica | hypothetical protein | 0.0146 | 0.0975 | 1 |
Echinococcus granulosus | TGF beta signal transducer SmadC | 0.0058 | 0.0319 | 0.0319 |
Brugia malayi | Pre-SET motif family protein | 0.0059 | 0.0325 | 0.0524 |
Schistosoma mansoni | family S12 unassigned peptidase (S12 family) | 0.0141 | 0.0937 | 0.0937 |
Brugia malayi | PHD-finger family protein | 0.0029 | 0.0108 | 0.0174 |
Echinococcus multilocularis | microtubule associated protein 2 | 0.1354 | 1 | 1 |
Schistosoma mansoni | histone-lysine n-methyltransferase setb1 | 0.0059 | 0.0325 | 0.0325 |
Loa Loa (eye worm) | hypothetical protein | 0.0039 | 0.0178 | 0.0286 |
Echinococcus multilocularis | beta LACTamase domain containing family member | 0.0141 | 0.0937 | 0.0937 |
Schistosoma mansoni | ferritin light chain | 0.0026 | 0.0085 | 0.0085 |
Loa Loa (eye worm) | TAR-binding protein | 0.0394 | 0.2831 | 0.4559 |
Echinococcus granulosus | mothers against decapentaplegic 2 | 0.0026 | 0.0081 | 0.0081 |
Loa Loa (eye worm) | pre-SET domain-containing protein family protein | 0.0408 | 0.2935 | 0.4727 |
Schistosoma mansoni | tar DNA-binding protein | 0.0394 | 0.2831 | 0.2831 |
Schistosoma mansoni | hypothetical protein | 0.0071 | 0.0419 | 0.0419 |
Onchocerca volvulus | 0.0141 | 0.0937 | 0.2616 | |
Onchocerca volvulus | Alhambra homolog | 0.0029 | 0.0108 | 0.0084 |
Loa Loa (eye worm) | hypothetical protein | 0.0141 | 0.0937 | 0.151 |
Echinococcus multilocularis | tumor protein p63 | 0.1021 | 0.7508 | 0.7508 |
Brugia malayi | acetyltransferase, GNAT family protein | 0.029 | 0.2055 | 0.3309 |
Trichomonas vaginalis | penicillin-binding protein, putative | 0.0141 | 0.0937 | 0.2793 |
Trichomonas vaginalis | set domain proteins, putative | 0.0464 | 0.3356 | 1 |
Schistosoma mansoni | transcription factor LCR-F1 | 0.0146 | 0.0975 | 0.0975 |
Schistosoma mansoni | histone-lysine n-methyltransferase setb1 | 0.0076 | 0.0454 | 0.0454 |
Plasmodium vivax | hypothetical protein, conserved | 0.0141 | 0.0937 | 1 |
Mycobacterium tuberculosis | Possible penicillin-binding protein | 0.0898 | 0.6592 | 1 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0033 | 0.0136 | 0.0406 |
Leishmania major | hypothetical protein, conserved | 0.0015 | 0.0004 | 0.0038 |
Echinococcus multilocularis | tar DNA binding protein | 0.0394 | 0.2831 | 0.2831 |
Loa Loa (eye worm) | hypothetical protein | 0.0029 | 0.0108 | 0.0174 |
Loa Loa (eye worm) | latrophilin receptor protein 2 | 0.0033 | 0.0134 | 0.0216 |
Schistosoma mansoni | hypothetical protein | 0.0033 | 0.0134 | 0.0134 |
Loa Loa (eye worm) | hypothetical protein | 0.0051 | 0.0265 | 0.0428 |
Entamoeba histolytica | hypothetical protein | 0.0146 | 0.0975 | 1 |
Echinococcus granulosus | FKBP12 rapamycin complex associated protein | 0.0045 | 0.0222 | 0.0222 |
Mycobacterium tuberculosis | Probable lipase LipD | 0.0141 | 0.0937 | 0.1311 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0033 | 0.0136 | 0.0406 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0024 | 0.0068 | 0.0202 |
Trichomonas vaginalis | ferritin, putative | 0.0026 | 0.0085 | 0.0252 |
Trypanosoma cruzi | PAB1-binding protein , putative | 0.0025 | 0.0076 | 0.0814 |
Loa Loa (eye worm) | hypothetical protein | 0.0141 | 0.0937 | 0.151 |
Mycobacterium tuberculosis | Conserved protein | 0.0141 | 0.0937 | 0.1311 |
Plasmodium falciparum | phd finger protein, putative | 0.0029 | 0.0108 | 0.0818 |
Mycobacterium leprae | conserved hypothetical protein | 0.0141 | 0.0937 | 1 |
Schistosoma mansoni | histone-lysine n-methyltransferase setb1 | 0.0076 | 0.0454 | 0.0454 |
Schistosoma mansoni | gcn5proteinral control of amino-acid synthesis 5-like 2 gcnl2 | 0.029 | 0.2055 | 0.2055 |
Entamoeba histolytica | hypothetical protein | 0.0146 | 0.0975 | 1 |
Echinococcus multilocularis | methyl CpG binding domain protein 2 | 0.0017 | 0.0017 | 0.0017 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.003 | 0.0112 | 0.0333 |
Leishmania major | hypothetical protein, conserved | 0.0025 | 0.0076 | 0.0814 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0038 | 0.0173 | 0.0515 |
Mycobacterium ulcerans | fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE | 0.0141 | 0.0937 | 1 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0026 | 0.0085 | 0.0255 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0024 | 0.0068 | 0.0203 |
Loa Loa (eye worm) | hypothetical protein | 0.0141 | 0.0937 | 0.151 |
Echinococcus granulosus | zinc finger protein | 0.0027 | 0.0088 | 0.0088 |
Schistosoma mansoni | thyroid hormone receptor | 0.0133 | 0.0878 | 0.0878 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0045 | 0.0227 | 0.0227 |
Echinococcus multilocularis | smad | 0.0058 | 0.0319 | 0.0319 |
Schistosoma mansoni | ferritin | 0.0026 | 0.0085 | 0.0085 |
Loa Loa (eye worm) | intermediate filament tail domain-containing protein | 0.0027 | 0.0089 | 0.0144 |
Brugia malayi | Pre-SET motif family protein | 0.0408 | 0.2935 | 0.4727 |
Onchocerca volvulus | 0.0027 | 0.0089 | 0.0027 | |
Mycobacterium tuberculosis | Conserved protein | 0.0141 | 0.0937 | 0.1311 |
Echinococcus granulosus | Transcription factor JmjC domain containing protein | 0.0097 | 0.0609 | 0.0609 |
Schistosoma mansoni | ataxia telangiectasia mutated (atm)-related | 0.0045 | 0.0222 | 0.0222 |
Plasmodium vivax | SET domain protein, putative | 0.0059 | 0.0325 | 0.2891 |
Schistosoma mansoni | hypothetical protein | 0.0015 | 0.0004 | 0.0004 |
Brugia malayi | RNA binding protein | 0.0394 | 0.2831 | 0.4559 |
Brugia malayi | Bromodomain containing protein | 0.0083 | 0.0506 | 0.0815 |
Brugia malayi | PHD-finger family protein | 0.0032 | 0.0129 | 0.0207 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0141 | 0.0937 | 1 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0036 | 0.0153 | 0.0457 |
Schistosoma mansoni | jumonji/arid domain-containing protein | 0.0038 | 0.0169 | 0.0169 |
Onchocerca volvulus | 0.0464 | 0.3356 | 1 | |
Trypanosoma cruzi | ISWI complex protein | 0.0015 | 0.0004 | 0.0038 |
Brugia malayi | intermediate filament protein | 0.0027 | 0.0089 | 0.0144 |
Loa Loa (eye worm) | transcription factor SMAD2 | 0.0847 | 0.6209 | 1 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0045 | 0.0222 | 0.066 |
Schistosoma mansoni | tar DNA-binding protein | 0.0394 | 0.2831 | 0.2831 |
Brugia malayi | MH1 domain containing protein | 0.0058 | 0.0319 | 0.0514 |
Echinococcus granulosus | histone acetyltransferase KAT2B | 0.028 | 0.1977 | 0.1977 |
Mycobacterium ulcerans | hypothetical protein | 0.0141 | 0.0937 | 1 |
Schistosoma mansoni | hypothetical protein | 0.0033 | 0.0134 | 0.0134 |
Schistosoma mansoni | TGF-beta signal transducer Smad2 | 0.0058 | 0.0319 | 0.0319 |
Trichomonas vaginalis | bromodomain-containing protein, putative | 0.0087 | 0.0538 | 0.1603 |
Echinococcus multilocularis | lamin dm0 | 0.0027 | 0.0089 | 0.0089 |
Mycobacterium tuberculosis | Probable lipase LipE | 0.0141 | 0.0937 | 0.1311 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0036 | 0.0153 | 0.0457 |
Brugia malayi | MH1 domain containing protein | 0.0032 | 0.0126 | 0.0204 |
Trypanosoma brucei | FAT domain/Rapamycin binding domain/Phosphatidylinositol 3- and 4-kinase, putative | 0.0019 | 0.0027 | 0.0284 |
Schistosoma mansoni | zinc finger protein | 0.0027 | 0.0088 | 0.0088 |
Brugia malayi | hypothetical protein | 0.0146 | 0.0975 | 0.1571 |
Schistosoma mansoni | tar DNA-binding protein | 0.0394 | 0.2831 | 0.2831 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0029 | 0.0105 | 0.0312 |
Loa Loa (eye worm) | bromodomain containing protein | 0.0025 | 0.0074 | 0.0119 |
Loa Loa (eye worm) | beta-LACTamase domain containing family member | 0.0141 | 0.0937 | 0.151 |
Mycobacterium leprae | Probable lipase LipE | 0.0141 | 0.0937 | 1 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0024 | 0.0068 | 0.0203 |
Loa Loa (eye worm) | phosphatidylinositol 3 | 0.0045 | 0.0222 | 0.0357 |
Brugia malayi | beta-lactamase family protein | 0.0141 | 0.0937 | 0.151 |
Brugia malayi | Intermediate filament tail domain containing protein | 0.0027 | 0.0089 | 0.0144 |
Loa Loa (eye worm) | hypothetical protein | 0.0104 | 0.0665 | 0.1071 |
Toxoplasma gondii | histone lysine acetyltransferase GCN5-A | 0.0087 | 0.0538 | 0.5361 |
Schistosoma mansoni | Smad4 | 0.0026 | 0.0081 | 0.0081 |
Mycobacterium tuberculosis | Probable esterase/lipase LipP | 0.0141 | 0.0937 | 0.1311 |
Onchocerca volvulus | 0.0141 | 0.0937 | 0.2616 | |
Trichomonas vaginalis | esterase, putative | 0.0141 | 0.0937 | 0.2793 |
Schistosoma mansoni | hypothetical protein | 0.0033 | 0.0134 | 0.0134 |
Loa Loa (eye worm) | jmjC domain-containing protein | 0.0061 | 0.0343 | 0.0552 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0045 | 0.0227 | 0.0227 |
Schistosoma mansoni | microtubule-associated protein tau | 0.1354 | 1 | 1 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0045 | 0.0227 | 0.0227 |
Trypanosoma cruzi | Phosphatidylinositol 3-kinase tor2 | 0.0045 | 0.0222 | 0.2364 |
Loa Loa (eye worm) | PHD-finger family protein | 0.0021 | 0.0044 | 0.0071 |
Brugia malayi | jmjC domain containing protein | 0.0038 | 0.0169 | 0.0272 |
Brugia malayi | hypothetical protein | 0.0025 | 0.0076 | 0.0123 |
Loa Loa (eye worm) | hypothetical protein | 0.0149 | 0.1003 | 0.1616 |
Trypanosoma brucei | phosphatidylinositol 3-kinase tor, putative | 0.0021 | 0.0046 | 0.0489 |
Echinococcus granulosus | smad | 0.0058 | 0.0319 | 0.0319 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0024 | 0.0068 | 0.0202 |
Loa Loa (eye worm) | MH2 domain-containing protein | 0.0026 | 0.0081 | 0.013 |
Trypanosoma cruzi | ISWI complex protein | 0.0015 | 0.0004 | 0.0038 |
Brugia malayi | Bromodomain containing protein | 0.0046 | 0.023 | 0.037 |
Echinococcus multilocularis | bromodomain adjacent to zinc finger domain | 0.0067 | 0.0391 | 0.0391 |
Brugia malayi | latrophilin 2 splice variant baaae | 0.0071 | 0.0419 | 0.0675 |
Entamoeba histolytica | hypothetical protein | 0.0146 | 0.0975 | 1 |
Schistosoma mansoni | methyl-cpg binding protein mbd | 0.0017 | 0.0017 | 0.0017 |
Schistosoma mansoni | zinc finger protein | 0.0015 | 0.0004 | 0.0004 |
Loa Loa (eye worm) | MH2 domain-containing protein | 0.0058 | 0.0319 | 0.0514 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0024 | 0.0068 | 0.0203 |
Echinococcus multilocularis | mothers against decapentaplegic 5 | 0.0058 | 0.0319 | 0.0319 |
Loa Loa (eye worm) | hypothetical protein | 0.0027 | 0.0089 | 0.0144 |
Trypanosoma brucei | ISWI complex protein | 0.0015 | 0.0004 | 0.0038 |
Schistosoma mansoni | hypothetical protein | 0.0029 | 0.0108 | 0.0108 |
Loa Loa (eye worm) | MH1 domain-containing protein | 0.0058 | 0.0319 | 0.0514 |
Echinococcus granulosus | Smad4 | 0.0058 | 0.0319 | 0.0319 |
Schistosoma mansoni | ferritin | 0.0026 | 0.0085 | 0.0085 |
Plasmodium vivax | histone acetyltransferase GCN5, putative | 0.0087 | 0.0538 | 0.5361 |
Leishmania major | target of rapamycin (TOR) kinase 2, putative | 0.0045 | 0.0222 | 0.2364 |
Echinococcus multilocularis | PHD finger protein rhinoceros | 0.0029 | 0.0108 | 0.0108 |
Brugia malayi | MH2 domain containing protein | 0.0058 | 0.0319 | 0.0514 |
Echinococcus granulosus | mothers against decapentaplegic 6 | 0.0026 | 0.0081 | 0.0081 |
Loa Loa (eye worm) | beta-lactamase | 0.0141 | 0.0937 | 0.151 |
Toxoplasma gondii | target of rapamycin (TOR), putative | 0.0033 | 0.0136 | 0.0695 |
Mycobacterium tuberculosis | Possible conserved lipoprotein LpqK | 0.0141 | 0.0937 | 0.1311 |
Loa Loa (eye worm) | jmjC domain-containing protein | 0.0038 | 0.0169 | 0.0272 |
Trypanosoma brucei | PAB1-binding protein , putative | 0.0025 | 0.0076 | 0.0814 |
Echinococcus multilocularis | Smad4 | 0.0058 | 0.0319 | 0.0319 |
Echinococcus multilocularis | Basic leucine zipper (bZIP) transcription | 0.0146 | 0.0975 | 0.0975 |
Schistosoma mansoni | ferritin | 0.0026 | 0.0085 | 0.0085 |
Schistosoma mansoni | Smad4 | 0.0026 | 0.0081 | 0.0081 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0033 | 0.0136 | 0.0406 |
Schistosoma mansoni | apoferritin-2 | 0.0026 | 0.0085 | 0.0085 |
Echinococcus granulosus | beta LACTamase domain containing family member | 0.0141 | 0.0937 | 0.0937 |
Leishmania major | target of rapamycin (TOR) kinase 1, putative | 0.0045 | 0.0222 | 0.2364 |
Toxoplasma gondii | histone lysine methyltransferase SET/SUV39 | 0.0059 | 0.0325 | 0.2891 |
Loa Loa (eye worm) | MH2 domain-containing protein | 0.0847 | 0.6209 | 1 |
Brugia malayi | Smad1 | 0.0058 | 0.0319 | 0.0514 |
Schistosoma mansoni | apoferritin-2 | 0.0026 | 0.0085 | 0.0085 |
Mycobacterium tuberculosis | Probable conserved lipoprotein | 0.0141 | 0.0937 | 0.1311 |
Schistosoma mansoni | thyroid hormone receptor | 0.0133 | 0.0878 | 0.0878 |
Giardia lamblia | Histone acetyltransferase GCN5 | 0.0078 | 0.0467 | 1 |
Echinococcus granulosus | expressed protein | 0.0026 | 0.0085 | 0.0085 |
Echinococcus multilocularis | Transcription factor, JmjC domain containing protein | 0.0097 | 0.0609 | 0.0609 |
Loa Loa (eye worm) | pigment dispersing factor receptor c | 0.0104 | 0.0665 | 0.1071 |
Schistosoma mansoni | ferritin light chain | 0.0026 | 0.0085 | 0.0085 |
Brugia malayi | RNA recognition motif domain containing protein | 0.0394 | 0.2831 | 0.4559 |
Trypanosoma brucei | Phosphatidylinositol 3-kinase tor1 | 0.0045 | 0.0222 | 0.2364 |
Echinococcus granulosus | lamin | 0.0027 | 0.0089 | 0.0089 |
Schistosoma mansoni | tar DNA-binding protein | 0.0394 | 0.2831 | 0.2831 |
Echinococcus granulosus | ferritin | 0.0026 | 0.0085 | 0.0085 |
Toxoplasma gondii | PHD-finger domain-containing protein | 0.0029 | 0.0108 | 0.0371 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0027 | 0.0087 | 0.026 |
Mycobacterium tuberculosis | Conserved protein | 0.0141 | 0.0937 | 0.1311 |
Activity type | Activity value | Assay description | Source | Reference |
---|---|---|---|---|
Decrease in SBP (functional) | = 19 % | Maximum percent fall in Systolic blood pressure (SBP) was measured in anesthetized normotensive rat for 30 mins after intravenous (iv) injection at 1 mg/kg dose | ChEMBL. | 8289193 |
Decrease in SBP (functional) | = 20 % | Maximum percent fall in Systolic blood pressure (SBP) was measured in anesthetized normotensive rat for 30 mins after intravenous (iv) injection at 3 mg/kg dose | ChEMBL. | 8289193 |
pEC100 (functional) | = 4.5 | Negative logarithm of the concentration causing a 100% inhibition of spontaneous mechanical activity in rat portal vein is determined in vitro | ChEMBL. | 8289193 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.
1 literature reference was collected for this gene.