Detailed information for compound 1381370

Basic information

Technical information
  • TDR Targets ID: 1381370
  • Name: [2-oxo-2-(4-phenylbutan-2-ylamino)ethyl] 1-me thylpyrrole-2-carboxylate
  • MW: 314.379 | Formula: C18H22N2O3
  • H donors: 1 H acceptors: 2 LogP: 2.94 Rotable bonds: 9
    Rule of 5 violations (Lipinski): 1
  • SMILES: CC(NC(=O)COC(=O)c1cccn1C)CCc1ccccc1
  • InChi: 1S/C18H22N2O3/c1-14(10-11-15-7-4-3-5-8-15)19-17(21)13-23-18(22)16-9-6-12-20(16)2/h3-9,12,14H,10-11,13H2,1-2H3,(H,19,21)
  • InChiKey: DBNOTJGWLVFEJT-UHFFFAOYSA-N  


Substructure search Similarity search

Network

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Synonyms

  • [2-[(1-methyl-3-phenyl-propyl)amino]-2-oxo-ethyl] 1-methylpyrrole-2-carboxylate
  • 1-methyl-2-pyrrolecarboxylic acid [2-[(1-methyl-3-phenylpropyl)amino]-2-oxoethyl] ester
  • 1-methylpyrrole-2-carboxylic acid [2-keto-2-[(1-methyl-3-phenyl-propyl)amino]ethyl] ester
  • T5273957

Targets

Known targets for this compound

Species Target name Source Bibliographic reference
Homo sapiens GNAS complex locus Starlite/ChEMBL No references
Homo sapiens geminin, DNA replication inhibitor Starlite/ChEMBL No references

Predicted pathogen targets for this compound

By orthology
Species Potential target Known druggable target/s Ortholog Group
Schistosoma japonicum ko:K04632 guanine nucleotide binding protein (G protein), alpha stimulating, putative Get druggable targets OG5_131088 All targets in OG5_131088
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) Get druggable targets OG5_131088 All targets in OG5_131088
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) Get druggable targets OG5_131088 All targets in OG5_131088
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) Get druggable targets OG5_131088 All targets in OG5_131088
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative Get druggable targets OG5_131088 All targets in OG5_131088
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit Get druggable targets OG5_131088 All targets in OG5_131088
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit Get druggable targets OG5_131088 All targets in OG5_131088
Echinococcus granulosus guanine nucleotide binding protein Gs subunit Get druggable targets OG5_131088 All targets in OG5_131088
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain Get druggable targets OG5_131088 All targets in OG5_131088
Echinococcus granulosus guanine nucleotide binding protein Gs subunit Get druggable targets OG5_131088 All targets in OG5_131088
By sequence similarity to non orthologous known druggable targets
Species Potential target Known druggable target Length Alignment span Identity
Brugia malayi Hypothetical 65.5 kDa Trp-Asp repeats containing protein F02E8.5 inchromosome X geminin, DNA replication inhibitor 209 aa 176 aa 27.8 %
Schistosoma mansoni GTP-binding protein alpha subunit gna GNAS complex locus 394 aa 450 aa 28.7 %
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Brugia malayi nicotinic acetylcholine receptor beta-1 chain precursor 0.008 0.0206 0.0236
Echinococcus multilocularis cpg binding protein 0.0091 0.0246 0.0244
Brugia malayi MH2 domain containing protein 0.0052 0.0109 0.0124
Schistosoma mansoni high-affinity choline transporter 0.0341 0.1117 0.1116
Mycobacterium ulcerans transmembrane cation transporter 0.0097 0.0266 0.1236
Trypanosoma cruzi hypothetical protein, conserved 0.0097 0.0266 0.0513
Schistosoma mansoni twik family of potassium channels-related 0.0097 0.0266 0.0264
Mycobacterium ulcerans hypothetical protein 0.0037 0.0059 0.0216
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0049 0.0099 0.0097
Loa Loa (eye worm) hypothetical protein 0.008 0.0206 0.0234
Toxoplasma gondii pyruvate dehydrogenase complex subunit PDH-E3II 0.0026 0.0019 0.0319
Plasmodium falciparum potassium channel 0.0097 0.0266 0.9002
Brugia malayi CAAX amino terminal protease family protein 0.0181 0.0558 0.0639
Loa Loa (eye worm) MBCTL1 0.0058 0.0129 0.0146
Mycobacterium ulcerans dihydrolipoamide dehydrogenase 0.0026 0.0019 0.0018
Loa Loa (eye worm) hypothetical protein 0.0026 0.0021 0.0022
Brugia malayi Tachykinin-like peptides receptor 99D 0.0412 0.1363 0.156
Echinococcus granulosus rhodopsin orphan GPCR 0.0412 0.1363 0.1361
Echinococcus granulosus Cys loop ligand gated ion channel subunit 0.0037 0.0057 0.0055
Mycobacterium tuberculosis Probable cytochrome P450 143 Cyp143 0.004 0.0067 0.0207
Chlamydia trachomatis pyruvate kinase 0.0068 0.0164 0.3985
Onchocerca volvulus 0.0186 0.0575 0.2724
Brugia malayi gamma-aminobutyric-acid receptor beta subunit precursor 0.008 0.0206 0.0236
Entamoeba histolytica calcium-gated potassium channel protein, putative 0.0097 0.0266 0.2063
Brugia malayi Twik (KCNK-like) family of potassium channels, alpha subunit 7 0.0097 0.0266 0.0304
Schistosoma mansoni family U48 unassigned peptidase (U48 family) 0.0181 0.0558 0.0557
Schistosoma mansoni neurotransmitter gated ion channel 0.0043 0.0078 0.0076
Echinococcus granulosus lysine specific demethylase 5A 0.0067 0.0163 0.0161
Loa Loa (eye worm) Sodium:neurotransmitter symporter family protein 0.0105 0.0295 0.0336
Echinococcus granulosus g protein coupled receptor 0.0412 0.1363 0.1361
Echinococcus multilocularis rhodopsin orphan GPCR 0.0412 0.1363 0.1361
Entamoeba histolytica Rad52/22 family double-strand break repair protein, putative 0.0111 0.0314 0.2438
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.008 0.0206 0.0236
Echinococcus multilocularis glutamate receptor subunit protein glur 0.0052 0.0109 0.0107
Loa Loa (eye worm) mbt repeat family protein 0.0051 0.0105 0.0118
Schistosoma mansoni hypothetical protein 0.1228 0.4204 0.4203
Trypanosoma cruzi peptidase with unknown catalytic mechanism (family U48) 0.0181 0.0558 0.1082
Loa Loa (eye worm) hypothetical protein 0.0097 0.0266 0.0302
Leishmania major cytochrome p450-like protein 0.004 0.0067 0.0128
Echinococcus multilocularis gamma aminobutyric acid receptor subunit 0.0037 0.0057 0.0055
Loa Loa (eye worm) CYP4Cod1 0.0066 0.016 0.0182
Echinococcus granulosus orexin receptor type 2 0.0412 0.1363 0.1361
Schistosoma mansoni flap endonuclease-1 0.0025 0.0016 0.0014
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0105 0.0295 0.0338
Echinococcus multilocularis intestinal type alkaline phosphatase 1 0.0319 0.1041 0.1039
Echinococcus multilocularis g protein coupled receptor 0.0412 0.1363 0.1361
Loa Loa (eye worm) hypothetical protein 0.032 0.1044 0.1193
Leishmania major CAAX prenyl protease 2, putative,peptidase with unknown catalytic mechanism (family U48) 0.0181 0.0558 0.1082
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0024 0.0011 0.001
Echinococcus granulosus sodium and chloride dependent glycine 0.0105 0.0295 0.0293
Onchocerca volvulus 0.0412 0.1363 0.6518
Mycobacterium ulcerans protoporphyrinogen oxidase 0.0041 0.0072 0.0282
Loa Loa (eye worm) hypothetical protein 0.0037 0.0057 0.0063
Trypanosoma cruzi ion transport protein, putative 0.0097 0.0266 0.0513
Echinococcus granulosus arachidonate 5 lipoxygenase 0.0056 0.0123 0.0121
Echinococcus multilocularis pyruvate kinase 0.0035 0.005 0.0048
Echinococcus multilocularis Jumonji, AT rich interactive domain 1B 0.0022 0.0004 0.0002
Schistosoma mansoni Lysine-specific histone demethylase 1 0.0041 0.0072 0.007
Brugia malayi Cytochrome P450 family protein 0.004 0.0067 0.0077
Schistosoma mansoni nAChR subunit (ShAR1-beta2-like) 0.008 0.0206 0.0204
Echinococcus granulosus acetylcholine receptor subunit beta 1 0.008 0.0206 0.0204
Loa Loa (eye worm) hypothetical protein 0.0023 0.0007 0.0007
Plasmodium falciparum glutathione reductase 0.0074 0.0188 0.6357
Echinococcus multilocularis thioredoxin glutathione reductase 0.0075 0.0191 0.019
Trichomonas vaginalis glucosylceramidase, putative 0.0284 0.0919 0.4493
Echinococcus granulosus twik family of potassium channels 0.0097 0.0266 0.0264
Trypanosoma cruzi hypothetical protein, conserved 0.0071 0.0177 0.034
Echinococcus granulosus nicotinic acetylcholine receptor subunit type 0.008 0.0206 0.0204
Onchocerca volvulus 0.0046 0.0088 0.038
Echinococcus multilocularis neuropeptide Y receptor 0.0412 0.1363 0.1361
Echinococcus granulosus glutamate NMDA receptor subunit 0.0052 0.0109 0.0107
Loa Loa (eye worm) hypothetical protein 0.0046 0.0088 0.0099
Echinococcus multilocularis lysosomal alpha glucosidase 0.0321 0.1045 0.1044
Loa Loa (eye worm) 5-hydroxytryptamine 2C receptor 0.0412 0.1363 0.1558
Onchocerca volvulus Cell death protein 3 homolog 0.0095 0.026 0.1208
Loa Loa (eye worm) hypothetical protein 0.0412 0.1363 0.1558
Trichomonas vaginalis Clan U, family U48, CaaX prenyl peptidase 2-like 0.0181 0.0558 0.2727
Mycobacterium ulcerans cytochrome P450 189A7 Cyp189A7 0.004 0.0067 0.0259
Loa Loa (eye worm) hypothetical protein 0.0105 0.0295 0.0336
Plasmodium falciparum dihydrolipoyl dehydrogenase, mitochondrial 0.0026 0.0019 0.0578
Giardia lamblia Hypothetical protein 0.0181 0.0558 0.4351
Treponema pallidum amino acid ABC transporter, periplasmic binding protein (hisJ) 0.0132 0.039 0.181
Brugia malayi G-protein coupled receptor 0.0412 0.1363 0.156
Trichomonas vaginalis spcc417.12 protein, putative 0.0046 0.0088 0.0423
Chlamydia trachomatis glutamine binding protein 0.0132 0.039 1
Trichomonas vaginalis pyruvate kinase, putative 0.0068 0.0164 0.0796
Trypanosoma cruzi C-14 sterol reductase, putative 0.0093 0.0251 0.0485
Schistosoma mansoni myosin xvIII 0.0412 0.1363 0.1361
Loa Loa (eye worm) hypothetical protein 0.0053 0.0113 0.0128
Loa Loa (eye worm) hypothetical protein 0.0825 0.2799 0.3203
Brugia malayi MH2 domain containing protein 0.0052 0.0109 0.0124
Onchocerca volvulus 0.0088 0.0235 0.1088
Brugia malayi hypothetical protein 0.0412 0.1363 0.156
Schistosoma mansoni norepinephrine/norepinephrine transporter 0.0105 0.0295 0.0293
Schistosoma mansoni neurotransmitter gated ion channel 0.0037 0.0057 0.0055
Schistosoma mansoni ancient conserved domain protein 2 (cyclin m2) 0.0412 0.1363 0.1361
Loa Loa (eye worm) hypothetical protein 0.0412 0.1363 0.1558
Trypanosoma brucei pyruvate kinase 1, putative 0.0068 0.0164 0.0316
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0195 0.0606 0.0694
Trichomonas vaginalis alpha-glucosidase, putative 0.0071 0.0177 0.0857
Brugia malayi putative neuropeptide receptor 0.0412 0.1363 0.156
Onchocerca volvulus 0.0412 0.1363 0.6518
Echinococcus multilocularis metabotropic glutamate receptor 2 0.0026 0.0021 0.0019
Loa Loa (eye worm) hypothetical protein 0.0412 0.1363 0.1558
Schistosoma mansoni gliotactin 0.0046 0.0088 0.0086
Brugia malayi Glycosyl hydrolases family 31 protein 0.0321 0.1045 0.1197
Echinococcus multilocularis muscleblind protein 0.0157 0.0475 0.0473
Schistosoma mansoni neurotransmitter gated ion channel 0.0037 0.0057 0.0055
Entamoeba histolytica DNA repair and recombination protein RAD52, putative 0.0389 0.1281 1
Brugia malayi Intermediate filament tail domain containing protein 0.0114 0.0327 0.0374
Toxoplasma gondii 4'-phosphopantetheinyl transferase superfamily protein 0.0025 0.0015 0.0249
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0076 0.0193 0.0191
Schistosoma mansoni neuropeptide receptor 0.0412 0.1363 0.1361
Trichomonas vaginalis bromodomain-containing protein, putative 0.0091 0.0246 0.1195
Echinococcus multilocularis rhodopsin orphan GPCR 0.0412 0.1363 0.1361
Loa Loa (eye worm) hypothetical protein 0.062 0.2085 0.2386
Brugia malayi Twik (KCNK-like) family of potassium channels, alpha subunit 5 0.0097 0.0266 0.0304
Trichomonas vaginalis NADH-ubiquinone oxidoreductase flavoprotein, putative 0.0157 0.0476 0.2324
Brugia malayi Importin beta-1 subunit 0.0028 0.0028 0.0032
Entamoeba histolytica glycosyl hydrolase, family 31 protein 0.0071 0.0177 0.1367
Mycobacterium leprae PROBABLE PROTOPORPHYRINOGEN OXIDASE HEMY (PROTOPORPHYRINOGEN-IX OXIDASE) (PROTOPORPHYRINOGENASE) (PPO) 0.0041 0.0072 0.1001
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0195 0.0606 0.0605
Mycobacterium ulcerans cytochrome P450 187A4 Cyp187A4 0.004 0.0067 0.0259
Echinococcus granulosus histone acetyltransferase KAT2B 0.0301 0.0977 0.0975
Mycobacterium tuberculosis Probable flavin-containing monoamine oxidase AofH (amine oxidase) (MAO) 0.0543 0.1821 0.7122
Schistosoma mansoni acetylcholine receptor subunit beta 0.0037 0.0057 0.0055
Echinococcus granulosus Glutamate receptor ionotropic kainate 2 0.0078 0.0201 0.0199
Leishmania major hypothetical protein, conserved 0.0097 0.0266 0.0513
Echinococcus multilocularis Glutamate receptor, ionotropic kainate 2 0.0078 0.0201 0.0199
Brugia malayi cytochrome P450 0.004 0.0067 0.0077
Loa Loa (eye worm) hypothetical protein 0.0041 0.0072 0.0081
Loa Loa (eye worm) glycosyl hydrolase family 31 protein 0.0071 0.0177 0.02
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0412 0.1363 0.1361
Loa Loa (eye worm) RGC/RGC protein kinase 0.0026 0.0021 0.0022
Schistosoma mansoni acetylcholinesterase 0.0046 0.0088 0.0086
Schistosoma mansoni Smad4 0.0023 0.0009 0.0007
Schistosoma mansoni nAChR subunit 0.008 0.0206 0.0204
Mycobacterium tuberculosis Probable dehydrogenase 0.017 0.052 0.1993
Trichomonas vaginalis alpha-glucosidase, putative 0.0027 0.0021 0.0095
Loa Loa (eye worm) hypothetical protein 0.0097 0.0266 0.0302
Plasmodium vivax thioredoxin reductase, putative 0.0074 0.0188 0.5523
Loa Loa (eye worm) hypothetical protein 0.0026 0.0021 0.0022
Schistosoma mansoni jumonji domain containing protein 0.0062 0.0146 0.0144
Echinococcus multilocularis fmrfamide receptor 0.0412 0.1363 0.1361
Echinococcus granulosus g-protein coupled receptor 0.0412 0.1363 0.1361
Brugia malayi beta-lactamase family protein 0.0118 0.0339 0.0388
Schistosoma mansoni Lamin B receptor (ERG24) 0.0093 0.0251 0.0249
Brugia malayi mothers against decapentaplegic homolog 3 0.0023 0.0009 0.001
Loa Loa (eye worm) hypothetical protein 0.0053 0.0113 0.0128
Brugia malayi Neurotransmitter-gated ion-channel transmembrane region family protein 0.0043 0.0078 0.0089
Loa Loa (eye worm) hypothetical protein 0.0097 0.0266 0.0302
Schistosoma mansoni nAChR subunit 0.008 0.0206 0.0204
Loa Loa (eye worm) hypothetical protein 0.0412 0.1363 0.1558
Loa Loa (eye worm) hypothetical protein 0.1279 0.438 0.5014
Trypanosoma cruzi C-14 sterol reductase, putative 0.0093 0.0251 0.0485
Mycobacterium ulcerans flavin-containing monoamine oxidase AofH 0.0585 0.1964 0.9608
Brugia malayi Muscleblind-like protein 0.0157 0.0475 0.0544
Plasmodium vivax protease, putative 0.0037 0.0059 0.169
Onchocerca volvulus 0.008 0.0206 0.0947
Schistosoma mansoni amine GPCR 0.0412 0.1363 0.1361
Toxoplasma gondii CMGC kinase, MAPK family (ERK) MAPK-1 0.0059 0.0134 0.2487
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0026 0.0019 0.0033
Toxoplasma gondii hypothetical protein 0.0105 0.0295 0.553
Trypanosoma brucei NADH dehydrogenase [ubiquinone] flavoprotein 1, mitochondrial 0.0157 0.0476 0.0922
Loa Loa (eye worm) hypothetical protein 0.0037 0.0057 0.0063
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0049 0.0099 0.0097
Plasmodium vivax potassium channel, putative 0.0097 0.0266 0.7822
Trypanosoma cruzi Lanosterol 14-alpha demethylase 0.004 0.0067 0.0128
Trypanosoma cruzi pyruvate kinase 2, putative 0.0068 0.0164 0.0316
Echinococcus granulosus BC026374 protein S09 family 0.0046 0.0088 0.0086
Plasmodium vivax amine transporter, putative 0.0105 0.0295 0.8689
Mycobacterium ulcerans esterase/lipase LipP 0.0118 0.0339 0.1598
Loa Loa (eye worm) hypothetical protein 0.0157 0.0475 0.0542
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0412 0.1363 0.1361
Echinococcus granulosus glycine receptor subunit beta 0.008 0.0206 0.0204
Echinococcus granulosus allatostatin A receptor 0.0412 0.1363 0.1361
Echinococcus granulosus neuropeptides capa receptor 0.0412 0.1363 0.1361
Mycobacterium tuberculosis Possible transmembrane cation transporter 0.0097 0.0266 0.0989
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0029 0.003 0.0028
Trypanosoma cruzi glycosyl hydrolase-like protein, putative 0.0027 0.0021 0.0038
Trypanosoma cruzi calcium-activated potassium channel, putative 0.0097 0.0266 0.0513
Trichomonas vaginalis alpha-glucosidase, putative 0.0027 0.0021 0.0095
Echinococcus multilocularis para nitrobenzyl esterase 0.0046 0.0088 0.0086
Echinococcus granulosus endonuclease exonuclease phosphatase 0.0219 0.0691 0.069
Loa Loa (eye worm) hypothetical protein 0.0026 0.0021 0.0022
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.0306 0.0993 0.7745
Echinococcus granulosus cytochrome P450 2K1 0.004 0.0067 0.0066
Schistosoma mansoni neuroligin 3 (S09 family) 0.0046 0.0088 0.0086
Chlamydia trachomatis protoporphyrinogen oxidase 0.0041 0.0072 0.1526
Loa Loa (eye worm) hypothetical protein 0.008 0.0206 0.0234
Echinococcus granulosus intermediate filament protein 0.0114 0.0327 0.0325
Schistosoma mansoni nAChR subunit 0.0037 0.0057 0.0055
Loa Loa (eye worm) hypothetical protein 0.0037 0.0057 0.0063
Mycobacterium ulcerans cytochrome p450 150 cyp150 0.004 0.0067 0.0259
Brugia malayi Neurotransmitter-gated ion-channel transmembrane region family protein 0.008 0.0206 0.0236
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0306 0.0993 0.4854
Echinococcus granulosus small conductance calcium activated potassium 0.2161 0.745 0.7449
Echinococcus multilocularis uncharacterized sodium dependent transporter 0.0105 0.0295 0.0293
Schistosoma mansoni sodium-dependent amino acid transporter 0.0105 0.0295 0.0293
Plasmodium vivax glutathione reductase, putative 0.0074 0.0188 0.5523
Loa Loa (eye worm) hypothetical protein 0.0043 0.0078 0.0087
Echinococcus granulosus carboxylesterase 5A 0.0271 0.0871 0.087
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0306 0.0993 0.4854
Loa Loa (eye worm) unidentified vitellogenin-linked transcript protein 6 0.0412 0.1363 0.1558
Echinococcus multilocularis solute carrier family 5 0.0038 0.006 0.0058
Loa Loa (eye worm) hypothetical protein 0.0029 0.0028 0.003
Echinococcus granulosus lysine specific histone demethylase 1A 0.0041 0.0072 0.007
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0105 0.0295 0.0338
Echinococcus granulosus glutamate receptor subunit protein glur 0.0052 0.0109 0.0107
Echinococcus granulosus neutral alpha glucosidase AB 0.0071 0.0177 0.0175
Brugia malayi glutathione reductase 0.0074 0.0188 0.0215
Trichomonas vaginalis maltase-glucoamylase, putative 0.0027 0.0021 0.0095
Echinococcus multilocularis glutamate receptor ionotropic kainate 0.0052 0.0109 0.0107
Chlamydia trachomatis hypothetical protein 0.0037 0.0059 0.1169
Echinococcus granulosus 3 hydroxyacyl coenzyme A dehydrogenase type 2 0.0058 0.013 0.0129
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0026 0.0019 0.0033
Schistosoma mansoni hypothetical protein 0.0412 0.1363 0.1361
Trypanosoma cruzi calcium/potassium channel (CAKC), putative 0.0097 0.0266 0.0513
Onchocerca volvulus 0.0105 0.0295 0.1376
Loa Loa (eye worm) hypothetical protein 0.0037 0.0057 0.0063
Echinococcus multilocularis twik family of potassium channels 0.0097 0.0266 0.0264
Loa Loa (eye worm) hypothetical protein 0.2161 0.745 0.8528
Loa Loa (eye worm) hypothetical protein 0.0046 0.0088 0.0099
Brugia malayi GTP-binding nuclear protein RAN/TC4 0.0021 0.0002 0.0002
Schistosoma mansoni family U48 unassigned peptidase (U48 family) 0.0181 0.0558 0.0557
Mycobacterium ulcerans glutaminase 0.0607 0.2044 1
Loa Loa (eye worm) hypothetical protein 0.0046 0.0088 0.0099
Schistosoma mansoni myelin transcription factor 1 myt1 0.0058 0.0129 0.0127
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0155 0.0467 0.0532
Echinococcus multilocularis acetylcholinesterase 0.0271 0.0871 0.087
Mycobacterium ulcerans cytochrome P450 108B4 Cyp108B4 0.004 0.0067 0.0259
Echinococcus multilocularis aldehyde dehydrogenase, mitochondrial 0.0059 0.0134 0.0132
Schistosoma mansoni smad1 5 8 and 0.0052 0.0109 0.0107
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0155 0.0467 0.0534
Trichomonas vaginalis cat eye syndrome critical region protein 2, cscr2, putative 0.0091 0.0246 0.1195
Trichomonas vaginalis glucosylceramidase, putative 0.0187 0.0578 0.2825
Echinococcus multilocularis NADH dehydrogenase (ubiquinone) flavoprotein 1 0.0157 0.0476 0.0475
Loa Loa (eye worm) cytochrome P450 family protein 0.0066 0.016 0.0182
Brugia malayi Calcitonin receptor-like protein seb-1 0.0155 0.0467 0.0534
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.008 0.0206 0.0236
Loa Loa (eye worm) hypothetical protein 0.0043 0.0078 0.0087
Loa Loa (eye worm) hypothetical protein 0.0038 0.006 0.0067
Schistosoma mansoni hypothetical protein 0.0049 0.0099 0.0097
Leishmania major alpha glucosidase II subunit, putative 0.0071 0.0177 0.034
Entamoeba histolytica CAAX prenyl protease family 0.0181 0.0558 0.4351
Schistosoma mansoni lamin 0.0114 0.0327 0.0325
Leishmania major importin beta-1 subunit, putative 0.0023 0.0009 0.0014
Plasmodium falciparum AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0098 0.0271 0.9203
Trichomonas vaginalis glucosylceramidase, putative 0.0187 0.0578 0.2825
Loa Loa (eye worm) hypothetical protein 0.0412 0.1363 0.1558
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0306 0.0993 0.4854
Plasmodium vivax histone acetyltransferase GCN5, putative 0.0091 0.0246 0.7234
Loa Loa (eye worm) hypothetical protein 0.0341 0.1117 0.1277
Loa Loa (eye worm) hypothetical protein 0.0412 0.1363 0.1558
Toxoplasma gondii HEAT repeat-containing protein 0.0028 0.0028 0.0493
Loa Loa (eye worm) hypothetical protein 0.0065 0.0154 0.0175
Onchocerca volvulus 0.0412 0.1363 0.6518
Schistosoma mansoni smad 0.0052 0.0109 0.0107
Trichomonas vaginalis alpha-glucosidase, putative 0.0027 0.0021 0.0095
Brugia malayi hypothetical protein 0.0037 0.0057 0.0065
Echinococcus multilocularis 7TM GPCR, rhodopsin 0.0412 0.1363 0.1361
Schistosoma mansoni norepinephrine/norepinephrine transporter 0.062 0.2085 0.2084
Brugia malayi glutaminase DH11.1 0.0607 0.2044 0.2339
Onchocerca volvulus Pyruvate kinase homolog 0.0068 0.0164 0.0747
Schistosoma mansoni Cys-loop ligand gated ion channel subunit 0.008 0.0206 0.0204
Loa Loa (eye worm) hypothetical protein 0.0412 0.1363 0.1558
Echinococcus multilocularis atpase aaa+ type core atpase aaa type core 0.2569 0.8873 0.8873
Loa Loa (eye worm) hypothetical protein 0.0901 0.3065 0.3507
Brugia malayi Trypsin family protein 0.0093 0.0253 0.0289
Echinococcus multilocularis histone acetyltransferase MYST2 0.0058 0.0129 0.0127
Loa Loa (eye worm) O-glycosyl hydrolase family 30 protein 0.0284 0.0919 0.105
Loa Loa (eye worm) hypothetical protein 0.0037 0.0057 0.0063
Loa Loa (eye worm) hypothetical protein 0.062 0.2085 0.2386
Echinococcus multilocularis voltage gated potassium channel 0.0023 0.0007 0.0006
Echinococcus granulosus thyrotropin releasing hormone receptor 0.0412 0.1363 0.1361
Loa Loa (eye worm) hypothetical protein 0.0097 0.0266 0.0302
Wolbachia endosymbiont of Brugia malayi exonuclease III 0.0098 0.0271 0.5562
Echinococcus granulosus Glutamate receptor ionotropic kainate 2 0.0078 0.0201 0.0199
Brugia malayi AKH receptor 0.0412 0.1363 0.156
Brugia malayi Cation transporter family protein 0.008 0.0206 0.0236
Onchocerca volvulus 0.0412 0.1363 0.6518
Leishmania major hypothetical protein, conserved 0.0118 0.0339 0.0656
Echinococcus granulosus histone acetyltransferase MYST2 0.0058 0.0129 0.0127
Echinococcus granulosus mixed lineage leukemia protein mll 0.0024 0.0011 0.001
Schistosoma mansoni sodium/chloride dependent neurotransmitter transporter 0.0105 0.0295 0.0293
Trypanosoma cruzi hypothetical protein, conserved 0.0118 0.0339 0.0656
Echinococcus multilocularis pyruvate kinase 0.0068 0.0164 0.0163
Loa Loa (eye worm) hypothetical protein 0.0023 0.0009 0.0009
Loa Loa (eye worm) hypothetical protein 0.0097 0.0266 0.0302
Echinococcus granulosus rhodopsin orphan GPCR 0.0412 0.1363 0.1361
Schistosoma mansoni glutaminase 0.0607 0.2044 0.2042
Schistosoma mansoni nAChR subunit 0.008 0.0206 0.0204
Echinococcus granulosus solute carrier family 5 0.0038 0.006 0.0058
Mycobacterium tuberculosis Conserved hypothetical protein 0.0037 0.0059 0.0173
Brugia malayi Glutamate receptor 2 precursor 0.0052 0.0109 0.0124
Plasmodium falciparum lysine-specific histone demethylase 1, putative 0.0041 0.0072 0.2402
Brugia malayi Carboxylesterase family protein 0.0046 0.0088 0.0101
Brugia malayi acetylcholine receptor, alpha-type subunit unc-38 precursor 0.008 0.0206 0.0236
Plasmodium vivax hypothetical protein, conserved 0.0118 0.0339 1
Echinococcus multilocularis neuropeptide FF receptor 2 0.0412 0.1363 0.1361
Trichomonas vaginalis alpha-glucosidase, putative 0.0071 0.0177 0.0857
Trypanosoma cruzi pyruvate kinase 2, putative 0.0068 0.0164 0.0316
Loa Loa (eye worm) hypothetical protein 0.0112 0.0319 0.0364
Loa Loa (eye worm) hypothetical protein 0.0412 0.1363 0.1558
Loa Loa (eye worm) nicotinic acetylcholine receptor non-alpha subunit 0.008 0.0206 0.0234
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.0114 0.0327 0.0372
Echinococcus granulosus lamin b receptor 0.0093 0.0251 0.0249
Schistosoma mansoni pyruvate kinase 0.0068 0.0164 0.0163
Loa Loa (eye worm) hypothetical protein 0.253 0.8735 1
Echinococcus multilocularis potassium voltage gated channel subfamily H 0.0023 0.0007 0.0006
Loa Loa (eye worm) hypothetical protein 0.0046 0.0088 0.0099
Loa Loa (eye worm) glycosyl hydrolase family 31 protein 0.0321 0.1045 0.1195
Onchocerca volvulus 0.0114 0.0327 0.1529
Brugia malayi exodeoxyribonuclease III family protein 0.0098 0.0271 0.0311
Loa Loa (eye worm) TWK-7 protein 0.0097 0.0266 0.0302
Echinococcus multilocularis sodium coupled monocarboxylate transporter 1 0.0038 0.006 0.0058
Brugia malayi Cytochrome P450 family protein 0.0066 0.016 0.0183
Echinococcus granulosus tm gpcr rhodopsin 0.0412 0.1363 0.1361
Brugia malayi Dopamine receptor 0.0412 0.1363 0.156
Toxoplasma gondii ABC1 family protein 0.0118 0.0339 0.6364
Loa Loa (eye worm) hypothetical protein 0.0412 0.1363 0.1558
Mycobacterium tuberculosis Probable NADH dehydrogenase I (chain F) NuoF (NADH-ubiquinone oxidoreductase chain F) 0.0157 0.0476 0.182
Loa Loa (eye worm) hypothetical protein 0.0114 0.0327 0.0372
Schistosoma mansoni aminoadipate-semialdehyde dehydrogenase 0.0088 0.0235 0.0233
Schistosoma mansoni dihydrolipoamide dehydrogenase 0.0026 0.0019 0.0017
Trichomonas vaginalis sucrase-isomaltase, putative 0.0071 0.0177 0.0857
Mycobacterium ulcerans cytochrome P450 51B1 Cyp51B1 0.004 0.0067 0.0259
Echinococcus granulosus pyruvate kinase 0.0035 0.005 0.0048
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0195 0.0606 0.0605
Schistosoma mansoni hypothetical protein 0.0052 0.0109 0.0107
Loa Loa (eye worm) hypothetical protein 0.0041 0.0072 0.0081
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0061 0.0139 0.0138
Echinococcus granulosus pyruvate kinase 0.0035 0.005 0.0048
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0071 0.0177 0.0857
Schistosoma mansoni BC026374 protein (S09 family) 0.0046 0.0088 0.0086
Echinococcus granulosus sodium:myo inositol cotransporter 0.0038 0.006 0.0058
Echinococcus multilocularis lysosomal alpha glucosidase 0.0321 0.1045 0.1044
Brugia malayi hypothetical protein 0.0097 0.0266 0.0304
Schistosoma mansoni nAChR subunit 0.008 0.0206 0.0204
Trichomonas vaginalis NADH-ubiquinone oxidoreductase flavoprotein, putative 0.0157 0.0476 0.2324
Leishmania major phosphopantetheinyl transferase-like protein 0.0025 0.0015 0.0026
Trichomonas vaginalis penicillin-binding protein, putative 0.0118 0.0339 0.1653
Schistosoma mansoni family S9 non-peptidase homologue (S09 family) 0.0271 0.0871 0.087
Loa Loa (eye worm) RGC/RGC protein kinase 0.0026 0.0021 0.0022
Mycobacterium tuberculosis Probable cytochrome P450 137 Cyp137 0.004 0.0067 0.0207
Mycobacterium ulcerans lipase LipD 0.0118 0.0339 0.1598
Echinococcus multilocularis dihydrolipoamide dehydrogenase 0.0026 0.0019 0.0017
Echinococcus granulosus peptide allatostatin:somatostatin 0.0412 0.1363 0.1361
Echinococcus multilocularis acetylcholine receptor subunit beta 1 0.008 0.0206 0.0204
Mycobacterium tuberculosis Probable soluble pyridine nucleotide transhydrogenase SthA (STH) (NAD(P)(+) transhydrogenase [B-specific]) (nicotinamide nucleot 0.0026 0.0019 0.0015
Schistosoma mansoni aldehyde dehydrogenase 0.0059 0.0134 0.0132
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0026 0.0019 0.0033
Brugia malayi metabotropic glutamate receptor type 2 0.0026 0.0021 0.0024
Loa Loa (eye worm) Sodium:neurotransmitter symporter family protein 0.0105 0.0295 0.0336
Onchocerca volvulus 0.0097 0.0266 0.1235
Schistosoma mansoni glutamate receptor kainate 0.0052 0.0109 0.0107
Loa Loa (eye worm) hypothetical protein 0.0155 0.0467 0.0532
Echinococcus multilocularis glycine receptor subunit beta 0.008 0.0206 0.0204
Loa Loa (eye worm) hypothetical protein 0.0412 0.1363 0.1558
Mycobacterium tuberculosis Probable fructose-bisphosphate aldolase Fba 0.0149 0.0449 0.171
Trichomonas vaginalis set domain proteins, putative 0.0501 0.1671 0.8178
Schistosoma mansoni hypothetical protein 0.0412 0.1363 0.1361
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0026 0.0019 0.0033
Echinococcus granulosus intestinal type alkaline phosphatase 1 0.0319 0.1041 0.1039
Loa Loa (eye worm) hypothetical protein 0.0412 0.1363 0.1558
Loa Loa (eye worm) hypothetical protein 0.0412 0.1363 0.1558
Loa Loa (eye worm) hypothetical protein 0.0412 0.1363 0.1558
Echinococcus multilocularis calcium activated potassium channel variant 0.0097 0.0266 0.0264
Brugia malayi neuropeptide F receptor 0.0412 0.1363 0.156
Echinococcus granulosus tm gpcr rhodopsin 0.0412 0.1363 0.1361
Trichomonas vaginalis glucosylceramidase, putative 0.0284 0.0919 0.4493
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0065 0.0154 0.0152
Brugia malayi Neurotransmitter-gated ion-channel transmembrane region family protein 0.008 0.0206 0.0236
Treponema pallidum amino acid ABC transporter, periplasmic binding protein 0.0132 0.039 0.181
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0065 0.0154 0.0152
Plasmodium falciparum conserved Plasmodium protein, unknown function 0.0041 0.0072 0.2402
Mycobacterium ulcerans cytochrome P450 105Q4 Cyp105Q4 0.004 0.0067 0.0259
Mycobacterium tuberculosis Probable lipase LipE 0.0118 0.0339 0.1279
Loa Loa (eye worm) RGC/RGC protein kinase 0.0026 0.0021 0.0022
Loa Loa (eye worm) latrophilin receptor protein 2 0.0049 0.0099 0.0111
Leishmania major hypothetical protein, conserved 0.0097 0.0266 0.0513
Echinococcus granulosus high affinity choline transporter 1 0.0341 0.1117 0.1116
Brugia malayi Serotonin receptor 0.0412 0.1363 0.156
Leishmania major mitogen activated protein kinase 4, putative;with=GeneDB:LmxM19.1440 0.0059 0.0134 0.0256
Loa Loa (eye worm) hypothetical protein 0.0097 0.0266 0.0302
Loa Loa (eye worm) MH2 domain-containing protein 0.0758 0.2568 0.2939
Brugia malayi G protein-coupled receptor F59B2.13 0.0412 0.1363 0.156
Echinococcus multilocularis alkaline phosphatase, intestinal, gene 2 0.0319 0.1041 0.1039
Toxoplasma gondii cytochrome p450 superfamily protein 0.004 0.0067 0.1241
Leishmania major NADH-ubiquinone oxidoreductase, mitochondrial, putative 0.0157 0.0476 0.0922
Schistosoma mansoni ATP-binding cassette transporter 0.0052 0.0109 0.0107
Schistosoma mansoni Cys-loop ligand gated ion channel subunit 0.008 0.0206 0.0204
Toxoplasma gondii ion channel protein 0.0097 0.0266 0.4978
Brugia malayi glutamate-gated chloride channel alpha3A subunit, putative 0.0043 0.0078 0.0089
Loa Loa (eye worm) pyruvate kinase 0.0068 0.0164 0.0186
Schistosoma mansoni peptide (allatostatin)-like receptor 0.0412 0.1363 0.1361
Echinococcus granulosus glutamate receptor 2 0.0078 0.0201 0.0199
Brugia malayi Neuronal acetylcholine receptor protein, alpha-2 chain precursor 0.0037 0.0057 0.0065
Loa Loa (eye worm) MH2 domain-containing protein 0.0023 0.0009 0.0009
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0118 0.0339 0.0337
Schistosoma mansoni sodium/chloride dependent transporter 0.062 0.2085 0.2084
Chlamydia trachomatis Ssodium-dependent amino acid transporter 0.0105 0.0295 0.7472
Echinococcus granulosus 7tm_1 domain containing protein 0.0412 0.1363 0.1361
Loa Loa (eye worm) hypothetical protein 0.0412 0.1363 0.1558
Loa Loa (eye worm) hypothetical protein 0.0041 0.0072 0.0081
Mycobacterium ulcerans cytochrome P450 143A4 Cyp143A4 0.004 0.0067 0.0259
Schistosoma mansoni family S9 non-peptidase homologue (S09 family) 0.0046 0.0088 0.0086
Echinococcus multilocularis nicotinic acetylcholine receptor beta 1 subunit 0.008 0.0206 0.0204
Schistosoma mansoni neuropeptide f receptor 76f 0.0412 0.1363 0.1361
Echinococcus multilocularis potassium channel subfamily K 8 0.0097 0.0266 0.0264
Schistosoma mansoni glutamate receptor kainate 0.0052 0.0109 0.0107
Trichomonas vaginalis glucosylceramidase, putative 0.0187 0.0578 0.2825
Echinococcus granulosus neuroligin 0.0046 0.0088 0.0086
Echinococcus multilocularis caspase 2 0.0095 0.026 0.0258
Plasmodium falciparum dihydrolipoyl dehydrogenase, apicoplast 0.0026 0.0019 0.0578
Schistosoma mansoni histamine-responsive GPCR (AAF21638) 0.0412 0.1363 0.1361
Echinococcus multilocularis somatostatin receptor 0.0412 0.1363 0.1361
Loa Loa (eye worm) TYRA-2 protein 0.0412 0.1363 0.1558
Trypanosoma brucei dihydrolipoamide dehydrogenase, point mutation 0.0026 0.0019 0.0033
Echinococcus multilocularis allatostatin A receptor 0.0412 0.1363 0.1361
Trypanosoma brucei hypothetical protein, conserved 0.0118 0.0339 0.0656
Schistosoma mansoni peptide (allatostatin/somatostatin)-like receptor 0.0412 0.1363 0.1361
Echinococcus granulosus rhodopsin orphan GPCR 0.0412 0.1363 0.1361
Brugia malayi intermediate filament protein 0.0114 0.0327 0.0374
Trypanosoma brucei hypothetical protein, conserved 0.0025 0.0015 0.0026
Onchocerca volvulus Putative nachr subunit 0.008 0.0206 0.0947
Trypanosoma brucei protein kinase, putative 0.0059 0.0134 0.0256
Onchocerca volvulus 0.0046 0.0088 0.038
Mycobacterium ulcerans flavoprotein disulfide reductase 0.0026 0.0019 0.0018
Treponema pallidum NADH oxidase 0.0026 0.0019 0.0018
Echinococcus granulosus glycine receptor subunit alpha 1 0.008 0.0206 0.0204
Loa Loa (eye worm) hypothetical protein 0.0058 0.0129 0.0146
Loa Loa (eye worm) serotonin transporter b 0.062 0.2085 0.2386
Schistosoma mansoni opsin-like receptor 0.0412 0.1363 0.1361
Brugia malayi Voltage-gated potassium channel, EAG (KCNH1)-related. C. elegans egl-2 ortholog 0.0023 0.0007 0.0009
Trichomonas vaginalis glutaminase, putative 0.0607 0.2044 1
Brugia malayi dihydrolipoyl dehydrogenase, mitochondrial precursor, putative 0.0026 0.0019 0.0021
Brugia malayi GH02984p 0.0341 0.1117 0.1279
Loa Loa (eye worm) hypothetical protein 0.0037 0.0057 0.0063
Mycobacterium leprae putative cytochrome p450 0.004 0.0067 0.0921
Echinococcus granulosus nicotinic acetylcholine receptor alpha subunit 0.008 0.0206 0.0204
Schistosoma mansoni hypothetical protein 0.0076 0.0193 0.0191
Echinococcus multilocularis carboxylesterase 5A 0.0271 0.0871 0.087
Schistosoma mansoni Cys-loop ligand gated ion channel subunit 0.008 0.0206 0.0204
Trichomonas vaginalis glucosylceramidase, putative 0.0187 0.0578 0.2825
Echinococcus granulosus uncharacterized sodium dependent transporter 0.0105 0.0295 0.0293
Brugia malayi Latrophilin receptor protein 2 0.0049 0.0099 0.0113
Mycobacterium tuberculosis Possible cytochrome P450 135B1 Cyp135B1 0.004 0.0067 0.0207
Mycobacterium tuberculosis Probable oxidoreductase 0.0189 0.0586 0.2253
Echinococcus multilocularis Two pore potassium channel protein sup 9 0.0097 0.0266 0.0264
Brugia malayi Twik (KCNK-like) family of potassium channels, alpha subunit 17 0.0097 0.0266 0.0304
Loa Loa (eye worm) hypothetical protein 0.0412 0.1363 0.1558
Echinococcus granulosus glycine receptor subunit alpha 1 0.008 0.0206 0.0204
Loa Loa (eye worm) hypothetical protein 0.0026 0.0021 0.0022
Loa Loa (eye worm) hypothetical protein 0.0097 0.0266 0.0302
Brugia malayi Pyruvate kinase, muscle isozyme 0.0068 0.0164 0.0188
Trypanosoma cruzi importin beta-1 subunit, putative 0.0023 0.0009 0.0014
Brugia malayi Dopamine receptor protein 1, putative (partial) 0.0412 0.1363 0.156
Mycobacterium tuberculosis Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB 0.017 0.052 0.1993
Plasmodium falciparum ataxin-2 like protein, putative 0.0027 0.0022 0.0685
Echinococcus multilocularis musashi 0.0114 0.0327 0.0325
Schistosoma mansoni nicotinic acetylcholine receptor alpha 0.0043 0.0078 0.0076
Mycobacterium ulcerans membrane protein ComEA 0.0035 0.0051 0.0177
Mycobacterium leprae Probable pyruvate kinase PykA 0.0068 0.0164 0.2614
Echinococcus multilocularis TGF beta signal transducer SmadC 0.0052 0.0109 0.0107
Trichomonas vaginalis alpha-glucosidase, putative 0.0027 0.0021 0.0095
Brugia malayi Twik (KCNK-like) family of potassium channels, alpha subunit 35 0.0097 0.0266 0.0304
Onchocerca volvulus 0.008 0.0206 0.0947
Schistosoma mansoni lipoxygenase 0.0056 0.0123 0.0121
Schistosoma mansoni calcium-activated potassium channel 0.182 0.6263 0.6263
Mycobacterium tuberculosis Cytochrome P450 121 Cyp121 0.004 0.0067 0.0207
Plasmodium falciparum histone acetyltransferase GCN5 0.0083 0.0219 0.7425
Leishmania major cytochrome p450-like protein 0.0066 0.016 0.0308
Loa Loa (eye worm) hypothetical protein 0.0041 0.0072 0.0081
Plasmodium vivax hypothetical protein, conserved 0.0041 0.0072 0.2087
Schistosoma mansoni transcription factor LCR-F1 0.0076 0.0193 0.0191
Echinococcus granulosus sex peptide receptor 0.0412 0.1363 0.1361
Plasmodium vivax dihydrolipoyl dehydrogenase, mitochondrial, putative 0.0026 0.0019 0.0502
Schistosoma mansoni hypothetical protein 0.0106 0.0296 0.0295
Mycobacterium tuberculosis Probable cytochrome P450 144 Cyp144 0.004 0.0067 0.0207
Echinococcus granulosus somatostatin receptor 0.0412 0.1363 0.1361
Brugia malayi cytoplasmic intermediate filament protein 0.0061 0.0142 0.0162
Onchocerca volvulus 0.0412 0.1363 0.6518
Trypanosoma cruzi calcium-activated potassium channel, putative 0.0097 0.0266 0.0513
Loa Loa (eye worm) hypothetical protein 0.0412 0.1363 0.1558
Echinococcus granulosus mitogen activated protein kinase 0.0059 0.0134 0.0132
Loa Loa (eye worm) carboxylesterase 0.0046 0.0088 0.0099
Entamoeba histolytica hypothetical protein 0.0076 0.0193 0.1494
Echinococcus multilocularis pyruvate kinase 0.0068 0.0164 0.0163
Echinococcus multilocularis high affinity choline transporter 1 0.0341 0.1117 0.1116
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0412 0.1363 0.1361
Loa Loa (eye worm) hypothetical protein 0.0097 0.0266 0.0302
Echinococcus granulosus caspase 2 0.0095 0.026 0.0258
Schistosoma mansoni cpg binding protein 0.0086 0.0229 0.0227
Mycobacterium tuberculosis Probable cytochrome P450 128 Cyp128 0.004 0.0067 0.0207
Toxoplasma gondii transporter, solute:sodium symporter (SSS) family protein 0.0038 0.006 0.1097
Echinococcus multilocularis mothers against decapentaplegic 5 0.0052 0.0109 0.0107
Trypanosoma brucei Lanosterol 14-alpha demethylase 0.004 0.0067 0.0128
Echinococcus granulosus sodium:chloride dependent neurotransmitter 0.0105 0.0295 0.0293
Onchocerca volvulus 0.0097 0.0266 0.1235
Echinococcus granulosus neuronal acetylcholine receptor subunit alpha 4 0.008 0.0206 0.0204
Treponema pallidum nitrogen fixation protein (rnfC) 0.0035 0.0051 0.0173
Echinococcus multilocularis small conductance calcium activated potassium 0.2161 0.745 0.7449
Toxoplasma gondii histone lysine-specific demethylase LSD1/BHC110/KDMA1A 0.0046 0.009 0.1673
Brugia malayi hypothetical protein 0.0412 0.1363 0.156
Brugia malayi mbt repeat family protein 0.0051 0.0105 0.012
Leishmania major hypothetical protein, conserved 0.0027 0.0022 0.0039
Onchocerca volvulus 0.0412 0.1363 0.6518
Schistosoma mansoni amine GPCR 0.0412 0.1363 0.1361
Plasmodium falciparum protease, putative 0.0037 0.0059 0.1945
Loa Loa (eye worm) metabotropic GABA-B receptor subtype 2 0.0026 0.0021 0.0022
Schistosoma mansoni hypothetical protein 0.0327 0.1068 0.1066
Brugia malayi neuropeptide F receptor 0.0412 0.1363 0.156
Loa Loa (eye worm) transcription factor SMAD2 0.0758 0.2568 0.2939
Echinococcus multilocularis cytoplasmic intermediate filament protein 0.0055 0.0121 0.0119
Echinococcus multilocularis potassium channel subfamily K 0.0097 0.0266 0.0264
Brugia malayi SWIRM domain containing protein 0.0041 0.0072 0.0083
Schistosoma mansoni adenoreceptor 0.0412 0.1363 0.1361
Brugia malayi RE15519p 0.0412 0.1363 0.156
Mycobacterium tuberculosis POSSIBLE PARA-NITROBENZYL ESTERASE (FRAGMENT) 0.0046 0.0088 0.0288
Echinococcus granulosus G protein coupled 5 hydroxytryptamine receptor 0.0412 0.1363 0.1361
Toxoplasma gondii histone lysine acetyltransferase GCN5-A 0.0091 0.0246 0.4604
Echinococcus granulosus GPCR family 2 0.0049 0.0099 0.0097
Schistosoma mansoni sodium/chloride dependent neurotransmitter transporter 0.0105 0.0295 0.0293
Mycobacterium tuberculosis NADPH-dependent mycothiol reductase Mtr 0.0074 0.0188 0.0683
Treponema pallidum sodium- and chloride- dependent transporter 0.062 0.2085 1
Loa Loa (eye worm) hypothetical protein 0.0037 0.0057 0.0063
Giardia lamblia Flap structure-specific endonuclease 0.0028 0.0025 0.0181
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0093 0.0253 0.0251
Trypanosoma cruzi cytochrome p450-like protein, putative 0.004 0.0067 0.0128
Trypanosoma brucei calcium/potassium channel (CAKC), putative 0.0097 0.0266 0.0513
Mycobacterium tuberculosis Probable cytochrome P450 141 Cyp141 0.004 0.0067 0.0207
Mycobacterium ulcerans fructose-bisphosphate aldolase 0.0149 0.0449 0.2138
Onchocerca volvulus 0.0051 0.0105 0.046
Loa Loa (eye worm) hypothetical protein 0.0043 0.0078 0.0087
Toxoplasma gondii Sodium:neurotransmitter symporter family protein 0.0105 0.0295 0.553
Echinococcus multilocularis metabotropic glutamate receptor 5 0.0026 0.0021 0.0019
Loa Loa (eye worm) hypothetical protein 0.0412 0.1363 0.1558
Echinococcus granulosus glutamate receptor ionotropic kainate 0.0052 0.0109 0.0107
Mycobacterium ulcerans carboxylesterase, LipT 0.0046 0.0088 0.036
Entamoeba histolytica hypothetical protein 0.0023 0.0009 0.0058
Loa Loa (eye worm) hypothetical protein 0.0097 0.0266 0.0302
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0412 0.1363 0.1361
Mycobacterium ulcerans monoamine oxidase 0.0041 0.0072 0.0282
Entamoeba histolytica Acid sphingomyelinase-like phosphodiesterase, putative 0.0184 0.057 0.4439
Echinococcus granulosus mothers against decapentaplegic 2 0.0023 0.0009 0.0007
Loa Loa (eye worm) hypothetical protein 0.0055 0.0121 0.0136
Brugia malayi Serotonin/octopamine receptor family protein 7 0.0412 0.1363 0.156
Schistosoma mansoni hypothetical protein 0.004 0.0067 0.0066
Mycobacterium tuberculosis Possible cytochrome P450 135A1 Cyp135A1 0.004 0.0067 0.0207
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0065 0.0154 0.0152
Loa Loa (eye worm) hypothetical protein 0.0037 0.0057 0.0063
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0026 0.0019 0.0033
Trichomonas vaginalis alpha-glucosidase, putative 0.0071 0.0177 0.0857
Brugia malayi Twik (KCNK-like) family of potassium channels, alpha subunit 19. C. elegans unc-58 ortholog 0.0097 0.0266 0.0304
Toxoplasma gondii hypothetical protein 0.0037 0.0059 0.1075
Loa Loa (eye worm) hypothetical protein 0.0412 0.1363 0.1558
Loa Loa (eye worm) hypothetical protein 0.0037 0.0057 0.0063
Trypanosoma cruzi sterol C-24 reductase, putative 0.0093 0.0251 0.0485
Loa Loa (eye worm) hypothetical protein 0.0026 0.0021 0.0022
Schistosoma mansoni nAChR subunit 0.0037 0.0057 0.0055
Onchocerca volvulus 0.008 0.0206 0.0947
Trypanosoma cruzi C-8 sterol isomerase, putative 0.1499 0.5148 1
Schistosoma mansoni smad1 5 8 and 0.0052 0.0109 0.0107
Loa Loa (eye worm) hypothetical protein 0.0097 0.0266 0.0302
Schistosoma mansoni nAChR subunit (ShAR1-beta-like) 0.008 0.0206 0.0204
Brugia malayi Pre-SET motif family protein 0.044 0.1461 0.1672
Brugia malayi hypothetical protein 0.0041 0.0072 0.0083
Echinococcus multilocularis serotonin receptor 0.1279 0.438 0.4379
Schistosoma mansoni glutamate receptor NMDA 0.0052 0.0109 0.0107
Mycobacterium ulcerans cytochrome P450 187A5 Cyp187A5 0.004 0.0067 0.0259
Loa Loa (eye worm) hypothetical protein 0.008 0.0206 0.0234
Leishmania major UDP-galactopyranose mutase 0.0041 0.0072 0.0137
Mycobacterium tuberculosis Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras 0.0189 0.0586 0.2253
Echinococcus granulosus nicotinic acetylcholine receptor subunit alpha 8 0.008 0.0206 0.0204
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0024 0.0011 0.001
Onchocerca volvulus 0.062 0.2085 1
Brugia malayi G protein-coupled receptor 0.0412 0.1363 0.156
Mycobacterium ulcerans flavin-containing monoamine oxidase AofH 0.0585 0.1964 0.9608
Loa Loa (eye worm) thioredoxin reductase 0.0074 0.0188 0.0213
Echinococcus multilocularis rhodopsin orphan GPCR 0.0412 0.1363 0.1361
Echinococcus multilocularis geminin 0.1436 0.4929 0.4928
Schistosoma mansoni sodium-dependent neurotransmitter transporter 0.0105 0.0295 0.0293
Echinococcus multilocularis protoporphyrinogen oxidase 0.0041 0.0072 0.007
Schistosoma mansoni twik family of potassium channels-related 0.0097 0.0266 0.0264
Mycobacterium tuberculosis Possible cytochrome P450 126 Cyp126 0.004 0.0067 0.0207
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0306 0.0993 0.4854
Mycobacterium tuberculosis Probable cytochrome P450 132 Cyp132 0.004 0.0067 0.0207
Schistosoma mansoni Protoporphyrinogen oxidase chloroplast/mitochondrial precursor 0.0041 0.0072 0.007
Leishmania major lanosterol 14-alpha-demethylase, putative 0.004 0.0067 0.0128
Treponema pallidum fructose-bisphosphate aldolase 0.0306 0.0993 0.4723
Brugia malayi F/Y-rich N-terminus family protein 0.0029 0.0028 0.0033
Mycobacterium tuberculosis Putative ferredoxin reductase 0.017 0.052 0.1993
Echinococcus multilocularis beta LACTamase domain containing family member 0.0118 0.0339 0.0337
Mycobacterium ulcerans cytochrome P450 136A2 Cyp136A2 0.004 0.0067 0.0259
Onchocerca volvulus 0.0076 0.0195 0.0894
Loa Loa (eye worm) hypothetical protein 0.0097 0.0266 0.0302
Leishmania major mitogen activated protein kinase, putative,map kinase, putative 0.0059 0.0134 0.0256
Plasmodium vivax pyruvate kinase 2, putative 0.0035 0.005 0.1421
Echinococcus granulosus mothers against decapentaplegic 6 0.0023 0.0009 0.0007
Echinococcus granulosus smad 0.0052 0.0109 0.0107
Schistosoma mansoni nAChR subunit 0.008 0.0206 0.0204
Echinococcus granulosus importin subunit beta 1 0.0028 0.0028 0.0026
Brugia malayi Dopamine receptor protein 1 0.253 0.8735 1
Plasmodium vivax hypothetical protein, conserved 0.0105 0.0295 0.8689
Trypanosoma cruzi NADH-ubiquinone oxidoreductase, mitochondrial, putative 0.0157 0.0476 0.0922
Echinococcus granulosus tm gpcr rhodopsin 0.2549 0.8801 0.8801
Brugia malayi Serotonin receptor 0.0865 0.294 0.3365
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0118 0.0339 0.0388
Brugia malayi MH2 domain containing protein 0.0023 0.0009 0.001
Loa Loa (eye worm) large conductance calcium-activated potassium channel alpha subunit ai 0.0097 0.0266 0.0302
Loa Loa (eye worm) hypothetical protein 0.008 0.0206 0.0234
Loa Loa (eye worm) hypothetical protein 0.0184 0.057 0.065
Toxoplasma gondii ion channel protein 0.0097 0.0266 0.4978
Echinococcus multilocularis pyruvate kinase 0.0035 0.005 0.0048
Echinococcus multilocularis receptor type guanylyl cyclase 0.0026 0.0021 0.0019
Echinococcus multilocularis serotonin transporter 0.062 0.2085 0.2084
Echinococcus granulosus metabotropic glutamate receptor 5 0.0026 0.0021 0.0019
Loa Loa (eye worm) nucleolar RNA-associated protein alpha 0.0304 0.0986 0.1127
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0412 0.1363 0.1361
Echinococcus multilocularis glutamate (NMDA) receptor subunit 0.0052 0.0109 0.0107
Mycobacterium ulcerans exodeoxyribonuclease III protein XthA 0.0098 0.0271 0.1265
Schistosoma mansoni inositol transporter 0.0038 0.006 0.0058
Mycobacterium ulcerans integral membrane protein 0.0037 0.0059 0.0216
Schistosoma mansoni sex comb on midleg homolog 0.0051 0.0105 0.0103
Echinococcus multilocularis glycine receptor subunit beta 0.008 0.0206 0.0204
Loa Loa (eye worm) receptor family ligand binding region containing protein 0.0026 0.0021 0.0022
Brugia malayi sulfakinin receptor protein 0.0412 0.1363 0.156
Brugia malayi hypothetical protein 0.0412 0.1363 0.156
Trypanosoma brucei CAAX amino terminal protease, putative 0.0181 0.0558 0.1082
Brugia malayi Sodium:neurotransmitter symporter family protein 1, putative 0.0105 0.0295 0.0338
Brugia malayi Voltage-gated potassium channel, HERG (KCNH2)-related. C. elegans unc-103 ortholog 0.0078 0.02 0.0229
Giardia lamblia Endonuclease/Exonuclease/phosphatase 0.0098 0.0271 0.2109
Echinococcus multilocularis pyruvate kinase 0.0053 0.0115 0.0113
Loa Loa (eye worm) pyruvate kinase-PB 0.0047 0.0093 0.0105
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.0098 0.0271 0.027
Echinococcus multilocularis glycine receptor subunit alpha 1 0.008 0.0206 0.0204
Loa Loa (eye worm) glutaminase 0.0607 0.2044 0.2338
Loa Loa (eye worm) Smad1 0.0052 0.0109 0.0122
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0195 0.0606 0.0605
Loa Loa (eye worm) hypothetical protein 0.0105 0.0295 0.0336
Schistosoma mansoni hypothetical protein 0.0076 0.0195 0.0193
Loa Loa (eye worm) hypothetical protein 0.0105 0.0295 0.0336
Brugia malayi hypothetical protein 0.0076 0.0195 0.0223
Onchocerca volvulus 0.0118 0.0339 0.1589
Mycobacterium ulcerans cytochrome P450 126A3 Cyp126A3 0.004 0.0067 0.0259
Brugia malayi amine oxidase, flavin-containing family protein 0.0041 0.0072 0.0083
Onchocerca volvulus 0.0114 0.0327 0.1529
Loa Loa (eye worm) hypothetical protein 0.0097 0.0266 0.0302
Loa Loa (eye worm) uncoordinated protein 58 0.0097 0.0266 0.0302
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0026 0.0019 0.0033
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0065 0.0154 0.0152
Schistosoma mansoni sodium/chloride dependent transporter 0.0106 0.0297 0.0295
Onchocerca volvulus 0.0118 0.0339 0.1589
Mycobacterium ulcerans beta-lactamase 0.0118 0.0339 0.1598
Loa Loa (eye worm) ACC-1 protein 0.008 0.0206 0.0234
Loa Loa (eye worm) hypothetical protein 0.0068 0.0165 0.0186
Plasmodium vivax protoporphyrinogen oxidase, putative 0.0041 0.0072 0.2087
Echinococcus multilocularis G protein coupled 5 hydroxytryptamine receptor 0.0412 0.1363 0.1361
Plasmodium vivax importin-beta 2, putative 0.0028 0.0028 0.0775
Echinococcus multilocularis Cys loop ligand gated ion channel subunit 0.0037 0.0057 0.0055
Schistosoma mansoni family S9 non-peptidase homologue (S09 family) 0.0046 0.0088 0.0086
Loa Loa (eye worm) hypothetical protein 0.008 0.0206 0.0234
Echinococcus granulosus potassium voltage gated channel subfamily H 0.0023 0.0007 0.0006
Echinococcus multilocularis endonuclease exonuclease phosphatase 0.0219 0.0691 0.069
Leishmania major flap endonuclease-1 (FEN-1), putative 0.0028 0.0025 0.0045
Echinococcus multilocularis pyroglutamylated rfamide peptide receptor 0.0412 0.1363 0.1361
Brugia malayi 3-hydroxyacyl-CoA dehydrogenase type II 0.0058 0.013 0.0149
Echinococcus multilocularis acetylcholinesterase 0.0271 0.0871 0.087
Brugia malayi Twik (KCNK-like) family of potassium channels, alpha subunit 28 0.0097 0.0266 0.0304
Trypanosoma cruzi sterol C-24 reductase, putative 0.0093 0.0251 0.0485
Onchocerca volvulus Huntingtin homolog 0.013 0.038 0.1786
Brugia malayi Neurotransmitter-gated ion-channel transmembrane region family protein 0.008 0.0206 0.0236
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0023 0.0009 0.0036
Echinococcus multilocularis apoptotic protease activating factor 1 0.0076 0.0195 0.0193
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0412 0.1363 0.1361
Mycobacterium ulcerans cytochrome P450 140A5 Cyp140A5 0.004 0.0067 0.0259
Mycobacterium ulcerans cytochrome P450 150A6 Cyp150A6 0.004 0.0067 0.0259
Onchocerca volvulus 0.0097 0.0266 0.1235
Schistosoma mansoni NADH-ubiquinone oxidoreductase 0.0157 0.0476 0.0475
Loa Loa (eye worm) hypothetical protein 0.0118 0.0339 0.0386
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0058 0.013 0.0568
Plasmodium falciparum thioredoxin reductase 0.0026 0.0019 0.0578
Entamoeba histolytica glycosyl hydrolase, family 31 protein 0.0071 0.0177 0.1367
Mycobacterium tuberculosis Probable cytochrome P450 130 Cyp130 0.004 0.0067 0.0207
Loa Loa (eye worm) MH1 domain-containing protein 0.0052 0.0109 0.0122
Echinococcus granulosus nicotinic acetylcholine receptor a11 subunit 0.008 0.0206 0.0204
Trypanosoma cruzi trypanothione reductase, putative 0.0026 0.0019 0.0033
Brugia malayi Pyruvate kinase, M2 isozyme 0.0068 0.0164 0.0188
Schistosoma mansoni hypothetical protein 0.0412 0.1363 0.1361
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0071 0.0177 0.0857
Onchocerca volvulus 0.008 0.0206 0.0947
Leishmania major apurinic/apyrimidinic endonuclease-redox protein 0.0098 0.0271 0.0524
Echinococcus granulosus lysosomal alpha glucosidase 0.0321 0.1045 0.1044
Loa Loa (eye worm) hypothetical protein 0.0097 0.0266 0.0302
Entamoeba histolytica hypothetical protein 0.0025 0.0015 0.0103
Brugia malayi MH1 domain containing protein 0.0052 0.0109 0.0124
Echinococcus multilocularis glutamate receptor 2 0.0078 0.0201 0.0199
Chlamydia trachomatis dihydrolipoyl dehydrogenase 0.0026 0.0019 0.0099
Brugia malayi Receptor family ligand binding region containing protein 0.0026 0.0021 0.0024
Echinococcus multilocularis thyrotropin releasing hormone receptor 0.0412 0.1363 0.1361
Echinococcus granulosus nAChR subunit 0.0043 0.0078 0.0076
Brugia malayi hypothetical protein 0.0097 0.0266 0.0304
Trypanosoma cruzi extracellular receptor, putative 0.0026 0.0021 0.0037
Echinococcus multilocularis microtubule associated protein 2 0.2893 1 1
Treponema pallidum exodeoxyribonuclease (exoA) 0.0098 0.0271 0.1239
Leishmania major cytochrome p450-like protein 0.004 0.0067 0.0128
Onchocerca volvulus Huntingtin homolog 0.013 0.038 0.1786
Toxoplasma gondii pyruvate kinase PyK1 0.0068 0.0164 0.3066
Echinococcus granulosus sodium coupled monocarboxylate transporter 1 0.0038 0.006 0.0058
Entamoeba histolytica Acid sphingomyelinase-like phosphodiesterase, putative 0.0184 0.057 0.4439
Plasmodium vivax pyruvate kinase, putative 0.0068 0.0164 0.4818
Onchocerca volvulus 0.0041 0.0072 0.0303
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0059 0.0134 0.0256
Toxoplasma gondii histone lysine acetyltransferase GCN5-B 0.0091 0.0246 0.4604
Mycobacterium tuberculosis Conserved hypothetical protein 0.0035 0.0051 0.0142
Trypanosoma cruzi cytochrome P450, putative 0.0066 0.016 0.0308
Loa Loa (eye worm) neuropeptide F receptor 0.0412 0.1363 0.1558
Trypanosoma brucei C-8 sterol isomerase, putative 0.1499 0.5148 1
Mycobacterium tuberculosis Probable esterase LipL 0.0118 0.0339 0.1279
Loa Loa (eye worm) hypothetical protein 0.008 0.0206 0.0234
Brugia malayi Twik (KCNK-like) family of potassium channels, alpha subunit 12 0.0097 0.0266 0.0304
Echinococcus multilocularis neutral alpha glucosidase AB 0.0071 0.0177 0.0175
Brugia malayi ERG2 and Sigma1 receptor like protein 0.1499 0.5148 0.5893
Brugia malayi Unidentified vitellogenin-linked transcript protein 6, putative 0.0412 0.1363 0.156
Loa Loa (eye worm) MH1 domain-containing protein 0.0023 0.0009 0.0009
Echinococcus granulosus pyroglutamylated rfamide peptide receptor 0.0412 0.1363 0.1361
Trypanosoma cruzi Lanosterol 14-alpha demethylase 0.004 0.0067 0.0128
Loa Loa (eye worm) jmjC domain-containing protein 0.0067 0.0163 0.0185
Loa Loa (eye worm) hypothetical protein 0.0412 0.1363 0.1558
Schistosoma mansoni amine GPCR 0.0759 0.2572 0.2571
Entamoeba histolytica hypothetical protein 0.0043 0.0078 0.0597
Brugia malayi beta-lactamase family protein 0.0118 0.0339 0.0388
Echinococcus granulosus neuropeptide FF receptor 2 0.0412 0.1363 0.1361
Schistosoma mansoni biogenic amine receptor 0.0412 0.1363 0.1361
Schistosoma mansoni pyruvate kinase 0.0035 0.005 0.0048
Schistosoma mansoni jumonji/arid domain-containing protein 0.0067 0.0163 0.0161
Echinococcus granulosus alkaline phosphatase intestinal gene 2 0.0319 0.1041 0.1039
Loa Loa (eye worm) hypothetical protein 0.0412 0.1363 0.1558
Loa Loa (eye worm) hypothetical protein 0.008 0.0206 0.0234
Echinococcus multilocularis snurportin 1 0.0304 0.0986 0.0985
Loa Loa (eye worm) cytochrome P450 family protein 0.0079 0.0202 0.023
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0412 0.1363 0.1361
Brugia malayi hypothetical protein 0.0076 0.0193 0.0221
Schistosoma mansoni protein kinase 0.0026 0.0021 0.0019
Loa Loa (eye worm) nuclear factor I 0.0029 0.0028 0.003
Mycobacterium tuberculosis Probable cytochrome P450 138 Cyp138 0.004 0.0067 0.0207
Entamoeba histolytica CAAX amino terminal protease family 0.0037 0.0059 0.0446
Brugia malayi MH2 domain containing protein 0.0758 0.2568 0.294
Brugia malayi hypothetical protein 0.0027 0.0022 0.0025
Schistosoma mansoni glutamate receptor AMPA 0.0052 0.0109 0.0107
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.044 0.1461 0.1671
Trypanosoma brucei dihydrolipoyl dehydrogenase 0.0026 0.0019 0.0033
Echinococcus multilocularis lamin b receptor 0.0093 0.0251 0.0249
Loa Loa (eye worm) glutaminase 2 0.0607 0.2044 0.2338
Loa Loa (eye worm) hypothetical protein 0.0412 0.1363 0.1558
Loa Loa (eye worm) hypothetical protein 0.0412 0.1363 0.1558
Echinococcus granulosus histone acetyltransferase KAT2B 0.0091 0.0246 0.0244
Trypanosoma brucei cytochrome P450, putative 0.0066 0.016 0.0308
Echinococcus granulosus NADH dehydrogenase ubiquinone flavoprotein 1 0.0157 0.0476 0.0475
Schistosoma mansoni twik family of potassium channels-related 0.0097 0.0266 0.0264
Schistosoma mansoni hypothetical protein 0.0412 0.1363 0.1361
Loa Loa (eye worm) metabotropic glutamate receptor 8 0.0026 0.0021 0.0022
Toxoplasma gondii Sodium:neurotransmitter symporter family protein 0.0105 0.0295 0.553
Schistosoma mansoni smad1 5 8 and 0.0052 0.0109 0.0107
Onchocerca volvulus 0.0037 0.0057 0.0228
Echinococcus multilocularis G-protein coupled receptor, putative 0.0412 0.1363 0.1361
Loa Loa (eye worm) hypothetical protein 0.0412 0.1363 0.1558
Echinococcus multilocularis glutamate receptor 2 0.0052 0.0109 0.0107
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0026 0.0019 0.0033
Trypanosoma cruzi hypothetical protein, conserved 0.0118 0.0339 0.0656
Echinococcus granulosus TGF beta signal transducer SmadC 0.0052 0.0109 0.0107
Echinococcus granulosus rhodopsin orphan GPCR 0.0412 0.1363 0.1361
Echinococcus granulosus para nitrobenzyl esterase 0.0046 0.0088 0.0086
Loa Loa (eye worm) hypothetical protein 0.0093 0.0253 0.0287
Echinococcus granulosus pyruvate kinase 0.0068 0.0164 0.0163
Echinococcus multilocularis peptide (allatostatin:somatostatin) 0.0412 0.1363 0.1361
Echinococcus multilocularis lamin 0.0114 0.0327 0.0325
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0027 0.0021 0.0095
Echinococcus granulosus flap endonuclease 1 0.0028 0.0025 0.0023
Echinococcus multilocularis serotonin receptor 0.1279 0.438 0.4379
Leishmania major calcium/potassium channel (CAKC), putative 0.0097 0.0266 0.0513
Loa Loa (eye worm) CXXC zinc finger family protein 0.0086 0.0229 0.026
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0026 0.0019 0.0033
Echinococcus multilocularis family S9 non peptidase ue (S09 family) 0.0046 0.0088 0.0086
Echinococcus multilocularis NMDA receptor 0.0052 0.0109 0.0107
Giardia lamblia Kinase, CMGC MAPK 0.0059 0.0134 0.1031
Trichomonas vaginalis D-aminoacylase, putative 0.0118 0.0339 0.1653
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0195 0.0606 0.0605
Onchocerca volvulus 0.0097 0.0266 0.1235
Mycobacterium tuberculosis Possible oxidoreductase 0.0041 0.0072 0.0226
Schistosoma mansoni microtubule-associated protein tau 0.2893 1 1
Mycobacterium ulcerans cytochrome P450 124A1, Cyp124A1 0.004 0.0067 0.0259
Brugia malayi jmjC domain containing protein 0.0062 0.0146 0.0167
Loa Loa (eye worm) hypothetical protein 0.013 0.038 0.0433
Echinococcus multilocularis Smad4 0.0052 0.0109 0.0107
Schistosoma mansoni cpg binding protein 0.0091 0.0246 0.0244
Onchocerca volvulus Glucosylceramidase homolog 0.0187 0.0578 0.2742
Brugia malayi Twik (KCNK-like) family of potassium channels, alpha subunit 13 0.0097 0.0266 0.0304
Schistosoma mansoni Smad4 0.0023 0.0009 0.0007
Brugia malayi O-Glycosyl hydrolase family 30 protein 0.0284 0.0919 0.1052
Schistosoma mansoni ap endonuclease 0.0098 0.0271 0.027
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0026 0.0019 0.0033
Schistosoma mansoni growth hormone secretagogue receptor 0.0412 0.1363 0.1361
Echinococcus granulosus sodium and chloride dependent glycine 0.0105 0.0295 0.0293
Echinococcus multilocularis Transcription factor, JmjC domain containing protein 0.0062 0.0146 0.0144
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.0118 0.0339 0.1279
Mycobacterium tuberculosis Probable conserved integral membrane protein 0.0037 0.0059 0.0173
Loa Loa (eye worm) hypothetical protein 0.0412 0.1363 0.1558
Loa Loa (eye worm) hypothetical protein 0.0068 0.0164 0.0186
Loa Loa (eye worm) hypothetical protein 0.0051 0.0105 0.0118
Echinococcus granulosus dnaJ subfamily C 6 0.006 0.0138 0.0137
Trypanosoma brucei flap endonuclease-1 (FEN-1), putative 0.0028 0.0025 0.0045
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0076 0.0193 0.0191
Onchocerca volvulus 0.0407 0.1347 0.6444
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0195 0.0606 0.0605
Leishmania major ion transport protein-like protein 0.0097 0.0266 0.0513
Brugia malayi metabotropic GABA-B receptor subtype 2 0.0026 0.0021 0.0024
Trichomonas vaginalis glucosylceramidase, putative 0.0197 0.0613 0.2996
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0195 0.0606 0.0605
Echinococcus granulosus snurportin 1 0.0304 0.0986 0.0985
Mycobacterium tuberculosis POSSIBLE PARA-NITROBENZYL ESTERASE (FRAGMENT) 0.0046 0.0088 0.0288
Echinococcus multilocularis mothers against decapentaplegic 6 0.0023 0.0009 0.0007
Loa Loa (eye worm) S-phase kinase-associated protein 1A 0.0097 0.0266 0.0302
Brugia malayi Cytochrome P450 family protein 0.0079 0.0202 0.0232
Trichomonas vaginalis alpha-glucosidase, putative 0.0027 0.0021 0.0095
Entamoeba histolytica Flap nuclease, putative 0.0028 0.0025 0.0181
Echinococcus multilocularis 3 hydroxyacyl coenzyme A dehydrogenase type 2 0.0058 0.013 0.0129
Plasmodium vivax dihydrolipoyl dehydrogenase, apicoplast, putative 0.0026 0.0019 0.0502
Brugia malayi GnHR receptor homolog 0.0412 0.1363 0.156
Schistosoma mansoni smad 0.0023 0.0009 0.0007
Echinococcus multilocularis nicotinic acetylcholine receptor subunit alpha 8 0.008 0.0206 0.0204
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0024 0.0011 0.001
Trichomonas vaginalis CMGC family protein kinase 0.0059 0.0134 0.0646
Echinococcus granulosus nicotinic acetylcholine receptor beta 1 subunit 0.008 0.0206 0.0204
Schistosoma mansoni biogenic amine receptor 0.0412 0.1363 0.1361
Echinococcus granulosus alkaline phosphatase 0.0319 0.1041 0.1039
Echinococcus multilocularis twik family of potassium channels 0.0097 0.0266 0.0264
Toxoplasma gondii exonuclease III APE 0.0098 0.0271 0.5089
Echinococcus multilocularis GPCR, family 2 0.0049 0.0099 0.0097
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.017 0.0519 0.2536
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0412 0.1363 0.1361
Schistosoma mansoni voltage-gated potassium channel 0.0085 0.0225 0.0224
Entamoeba histolytica hypothetical protein 0.0076 0.0193 0.1494
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0097 0.0266 0.1293
Schistosoma mansoni voltage-gated potassium channel 0.0023 0.0007 0.0006
Echinococcus multilocularis dnaJ subfamily B 0.1228 0.4204 0.4203
Echinococcus granulosus Glutamate receptor ionotropic kainate 2 0.0078 0.0201 0.0199
Mycobacterium tuberculosis Probable glutamine-binding lipoprotein GlnH (GLNBP) 0.0132 0.039 0.1478
Loa Loa (eye worm) hypothetical protein 0.0041 0.0072 0.0081
Echinococcus granulosus 7TM GPCR rhodopsin 0.0412 0.1363 0.1361
Leishmania major acetoin dehydrogenase e3 component-like protein 0.0026 0.0019 0.0033
Onchocerca volvulus 0.0097 0.0266 0.1235
Echinococcus granulosus neuropeptide receptor 0.0412 0.1363 0.1361
Loa Loa (eye worm) hypothetical protein 0.0097 0.0266 0.0302
Echinococcus granulosus neuropeptide Y receptor 0.0412 0.1363 0.1361
Mycobacterium ulcerans aldehyde dehydrogenase 0.0059 0.0134 0.0585
Schistosoma mansoni hypothetical protein 0.0049 0.0099 0.0097
Schistosoma mansoni sodium-dependent neurotransmitter transporter 0.0105 0.0295 0.0293
Echinococcus granulosus uncharacterized sodium dependent transporter 0.0105 0.0295 0.0293
Echinococcus multilocularis alkaline phosphatase 0.0319 0.1041 0.1039
Schistosoma mansoni biogenic amine (octopamine/dopamine) receptor 0.0412 0.1363 0.1361
Trichomonas vaginalis glucosylceramidase, putative 0.0187 0.0578 0.2825
Plasmodium falciparum thioredoxin reductase 0.0074 0.0188 0.6357
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0037 0.0057 0.0065
Trypanosoma brucei trypanothione reductase 0.0074 0.0188 0.0362
Loa Loa (eye worm) melatonin receptor type 1A 0.0412 0.1363 0.1558
Loa Loa (eye worm) hypothetical protein 0.0412 0.1363 0.1558
Echinococcus granulosus voltage gated potassium channel 0.0023 0.0007 0.0006
Plasmodium falciparum importin beta, putative 0.0028 0.0028 0.0892
Leishmania major trypanothione reductase 0.0074 0.0188 0.0362
Plasmodium falciparum ataxin-2 like protein, putative 0.0027 0.0022 0.0685
Echinococcus granulosus suppression of tumorigenicity 18 protein 0.0058 0.0129 0.0127
Echinococcus multilocularis nmda type glutamate receptor 0.0026 0.0021 0.0019
Trichomonas vaginalis D-aminoacylase, putative 0.0118 0.0339 0.1653
Mycobacterium ulcerans cytochrome P450 123A3 Cyp123A3 0.004 0.0067 0.0259
Brugia malayi Cell death protein 3 precursor 0.0095 0.026 0.0298
Schistosoma mansoni sodium/chloride dependent transporter 0.0105 0.0295 0.0293
Onchocerca volvulus 0.0412 0.1363 0.6518
Loa Loa (eye worm) 3-hydroxyacyl-CoA dehydrogenase type II 0.0054 0.0117 0.0132
Trichomonas vaginalis CMGC family protein kinase 0.0059 0.0134 0.0646
Mycobacterium ulcerans cytochrome P450 142A3 Cyp142A3 0.004 0.0067 0.0259
Echinococcus multilocularis Glutamate receptor, ionotropic kainate 3 0.0184 0.0569 0.0568
Plasmodium falciparum glutathione reductase 0.0026 0.0019 0.0578
Brugia malayi Glycosyl hydrolases family 31 protein 0.0071 0.0177 0.0202
Leishmania major glycosyl hydrolase-like protein 0.0027 0.0021 0.0038
Echinococcus granulosus neuropeptide s receptor 0.0412 0.1363 0.1361
Trichomonas vaginalis importin beta-1, putative 0.0023 0.0009 0.0036
Loa Loa (eye worm) NADH-ubiquinone oxidoreductase 51 kDa subunit 0.0157 0.0476 0.0543
Mycobacterium tuberculosis Probable cytochrome P450 136 Cyp136 0.004 0.0067 0.0207
Echinococcus granulosus rhodopsin orphan GPCR 0.0412 0.1363 0.1361
Echinococcus granulosus apoptotic protease activating factor 1 0.0076 0.0195 0.0193
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.0306 0.0993 0.7745
Schistosoma mansoni hypothetical protein 0.0166 0.0506 0.0505
Loa Loa (eye worm) G-protein-linked acetylcholine receptor protein 2 0.0412 0.1363 0.1558
Mycobacterium leprae DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE 0.0189 0.0586 1
Schistosoma mansoni twik family of potassium channels-related 0.0097 0.0266 0.0264
Echinococcus granulosus Ribosomal protein S1 RNA binding domain 0.0052 0.0109 0.0107
Loa Loa (eye worm) hypothetical protein 0.0037 0.0057 0.0063
Trypanosoma cruzi PAB1-binding protein , putative 0.0027 0.0022 0.0039
Mycobacterium ulcerans oxidoreductase 0.0041 0.0072 0.0282
Echinococcus granulosus twik family of potassium channels 0.0097 0.0266 0.0264
Echinococcus multilocularis growth hormone secretagogue receptor type 1 0.0412 0.1363 0.1361
Trypanosoma cruzi ion transport protein, putative 0.0097 0.0266 0.0513
Loa Loa (eye worm) hypothetical protein 0.0037 0.0057 0.0063
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0195 0.0606 0.0605
Loa Loa (eye worm) norepinephrine transporter 0.062 0.2085 0.2386
Brugia malayi Metabotropic glutamate receptor precursor. 0.0026 0.0021 0.0024
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0412 0.1363 0.1361
Echinococcus granulosus biogenic amine 5HT receptor 0.0778 0.2637 0.2636
Loa Loa (eye worm) hypothetical protein 0.0097 0.0266 0.0302
Echinococcus multilocularis atrial natriuretic peptide receptor 0.0026 0.0021 0.0019
Onchocerca volvulus 0.0038 0.006 0.0244
Mycobacterium tuberculosis NAD(P)H quinone reductase LpdA 0.0189 0.0586 0.2253
Leishmania major 3-oxoacyl-(acyl-carrier protein) reductase, putative 0.0058 0.013 0.025
Echinococcus multilocularis lysine specific histone demethylase 1A 0.0041 0.0072 0.007
Brugia malayi hypothetical protein 0.013 0.038 0.0435
Onchocerca volvulus Dopamine\/Ecdysteroid receptor homolog 0.0412 0.1363 0.6518
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0026 0.0019 0.0033
Loa Loa (eye worm) hypothetical protein 0.0412 0.1363 0.1558
Schistosoma mansoni nAChR subunit 0.008 0.0206 0.0204
Echinococcus multilocularis neuropeptide receptor 0.0412 0.1363 0.1361
Loa Loa (eye worm) hypothetical protein 0.008 0.0206 0.0234
Loa Loa (eye worm) hypothetical protein 0.0043 0.0078 0.0087
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0105 0.0295 0.0338
Leishmania major aldehyde dehydrogenase, mitochondrial precursor 0.0059 0.0134 0.0256
Echinococcus multilocularis mitogen activated protein kinase 0.0059 0.0134 0.0132
Loa Loa (eye worm) hypothetical protein 0.0049 0.0099 0.0111
Loa Loa (eye worm) hypothetical protein 0.062 0.2085 0.2386
Mycobacterium ulcerans cytochrome P450 125A7 Cyp125A7 0.004 0.0067 0.0259
Echinococcus granulosus sodium:glucose cotransporter 0.0038 0.006 0.0058
Echinococcus granulosus muscleblind protein 0.0157 0.0475 0.0473
Brugia malayi follicle stimulating hormone receptor 0.0638 0.2149 0.246
Schistosoma mansoni cytochrome P450 0.004 0.0067 0.0066
Trypanosoma brucei glucosidase, putative 0.0071 0.0177 0.034
Schistosoma mansoni opsin-like receptor 0.0412 0.1363 0.1361
Loa Loa (eye worm) histone methyltransferase 0.0029 0.003 0.0032
Schistosoma mansoni alpha glucosidase 0.0071 0.0177 0.0175
Echinococcus multilocularis 0.0041 0.0072 0.007
Loa Loa (eye worm) hypothetical protein 0.008 0.0206 0.0234
Echinococcus multilocularis importin subunit beta 1 0.0028 0.0028 0.0026
Echinococcus multilocularis 0.004 0.0067 0.0066
Brugia malayi Twik (KCNK-like) family of potassium channels, alpha subunit 39B 0.0097 0.0266 0.0304
Loa Loa (eye worm) hypothetical protein 0.0412 0.1363 0.1558
Echinococcus multilocularis rhodopsin orphan GPCR 0.0412 0.1363 0.1361
Plasmodium vivax holo-[acyl-carrier-protein] synthase, putative 0.0025 0.0015 0.0392
Loa Loa (eye worm) glutamate receptor 1 0.0052 0.0109 0.0122
Toxoplasma gondii thioredoxin reductase 0.0074 0.0188 0.3515
Echinococcus multilocularis dro:myosuppressin receptor 0.0412 0.1363 0.1361
Loa Loa (eye worm) TWK-28 protein 0.0097 0.0266 0.0302
Loa Loa (eye worm) hypothetical protein 0.0105 0.0295 0.0336
Brugia malayi Cation transporter family protein 0.008 0.0206 0.0236
Trypanosoma cruzi calcium/potassium channel (CAKC), putative 0.0097 0.0266 0.0513
Loa Loa (eye worm) LGC-31 protein 0.008 0.0206 0.0234
Mycobacterium tuberculosis Probable cytochrome P450 125 Cyp125 0.004 0.0067 0.0207
Brugia malayi hypothetical protein 0.0412 0.1363 0.156
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0065 0.0154 0.0152
Loa Loa (eye worm) flap endonuclease-1 0.0028 0.0025 0.0027
Echinococcus multilocularis neuropeptide s receptor 0.0412 0.1363 0.1361
Entamoeba histolytica CAAX amino terminal protease family 0.0037 0.0059 0.0446
Trichomonas vaginalis alpha-glucosidase, putative 0.0071 0.0177 0.0857
Loa Loa (eye worm) hypothetical protein 0.0095 0.026 0.0296
Leishmania major extracellular receptor, putative 0.0026 0.0021 0.0037
Loa Loa (eye worm) hypothetical protein 0.008 0.0206 0.0234
Echinococcus granulosus glutamate receptor ionotropic kainate 3 0.0052 0.0109 0.0107
Loa Loa (eye worm) cytochrome P450 family protein 0.0066 0.016 0.0182
Schistosoma mansoni TGF-beta signal transducer Smad2 0.0052 0.0109 0.0107
Loa Loa (eye worm) neuropeptide F receptor 0.0412 0.1363 0.1558
Onchocerca volvulus 0.008 0.0206 0.0947
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0065 0.0154 0.2875
Echinococcus granulosus Smad4 0.0052 0.0109 0.0107
Schistosoma mansoni hypothetical protein 0.1436 0.4929 0.4928
Plasmodium falciparum pyruvate kinase 0.0068 0.0164 0.5545
Onchocerca volvulus 0.0026 0.0021 0.0057
Loa Loa (eye worm) hypothetical protein 0.0105 0.0295 0.0336
Toxoplasma gondii CAAX amino terminal protease family protein 0.0037 0.0059 0.1075
Echinococcus granulosus Cys loop ligand gated ion channel subunit 0.008 0.0206 0.0204
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.0098 0.0271 0.0524
Loa Loa (eye worm) hypothetical protein 0.0412 0.1363 0.1558
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0412 0.1363 0.1361
Leishmania major 2-oxoglutarate dehydrogenase, e3 component, lipoamidedehydrogenase-like protein 0.0026 0.0019 0.0033
Trypanosoma cruzi hypothetical protein, conserved 0.0071 0.0177 0.034
Schistosoma mansoni amine oxidase 0.0041 0.0072 0.007
Loa Loa (eye worm) hypothetical protein 0.0412 0.1363 0.1558
Echinococcus granulosus nAChR subunit 0.008 0.0206 0.0204
Echinococcus multilocularis sodium:chloride dependent neurotransmitter 0.0105 0.0295 0.0293
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0049 0.0099 0.0113
Echinococcus multilocularis glutamate receptor 2 0.0026 0.0021 0.0019
Echinococcus multilocularis gcn5proteinral control of amino acid synthesis 0.031 0.1007 0.1005
Echinococcus multilocularis fmrfamide receptor 0.0412 0.1363 0.1361
Echinococcus granulosus aldehyde dehydrogenase mitochondrial 0.0059 0.0134 0.0132
Onchocerca volvulus 0.0412 0.1363 0.6518
Loa Loa (eye worm) hypothetical protein 0.0766 0.2596 0.2971
Giardia lamblia Histone acetyltransferase GCN5 0.0083 0.0219 0.1701
Brugia malayi jmjC domain containing protein 0.0067 0.0163 0.0186
Entamoeba histolytica acetyltransferase, GNAT family 0.0083 0.0219 0.1701
Onchocerca volvulus 0.0412 0.1363 0.6518
Entamoeba histolytica hypothetical protein 0.0111 0.0314 0.2438
Onchocerca volvulus 0.0105 0.0295 0.1376
Loa Loa (eye worm) hypothetical protein 0.0097 0.0266 0.0302
Trichomonas vaginalis glucosylceramidase, putative 0.0187 0.0578 0.2825
Mycobacterium leprae PROBABLE NADH DEHYDROGENASE NDH 0.017 0.052 0.8845
Schistosoma mansoni metabotropic glutamate receptor 0.0026 0.0021 0.0019
Schistosoma mansoni neuropeptide receptor 0.0412 0.1363 0.1361
Echinococcus multilocularis intestinal type alkaline phosphatase 0.0319 0.1041 0.1039
Echinococcus granulosus histone lysine methyltransferase setb 0.0065 0.0154 0.0152
Loa Loa (eye worm) hypothetical protein 0.0097 0.0266 0.0302
Loa Loa (eye worm) hypothetical protein 0.0037 0.0057 0.0063
Brugia malayi aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase 0.0088 0.0235 0.0269
Schistosoma mansoni aldehyde dehydrogenase 0.0059 0.0134 0.0132
Onchocerca volvulus 0.0412 0.1363 0.6518
Loa Loa (eye worm) hypothetical protein 0.0097 0.0266 0.0302
Brugia malayi Carboxylesterase family protein 0.0046 0.0088 0.0101
Loa Loa (eye worm) hypothetical protein 0.0118 0.0339 0.0386
Loa Loa (eye worm) hypothetical protein 0.0181 0.0558 0.0637
Toxoplasma gondii LsmAD domain-containing protein 0.0027 0.0022 0.0379
Brugia malayi hypothetical protein 0.0026 0.0021 0.0024
Entamoeba histolytica hypothetical protein 0.0026 0.0021 0.015
Brugia malayi hypothetical protein 0.0046 0.0088 0.0101
Loa Loa (eye worm) hypothetical protein 0.008 0.0206 0.0234
Brugia malayi NADH-ubiquinone oxidoreductase 51 kDa subunit, mitochondrial precursor 0.0157 0.0476 0.0545
Trichomonas vaginalis carboxylesterase domain containing protein, putative 0.0046 0.0088 0.0423
Toxoplasma gondii NADPH-glutathione reductase 0.0026 0.0019 0.0319
Entamoeba histolytica hypothetical protein 0.0076 0.0193 0.1494
Onchocerca volvulus 0.0087 0.0231 0.1071
Echinococcus multilocularis rhodopsin orphan GPCR 0.0412 0.1363 0.1361
Loa Loa (eye worm) hypothetical protein 0.0097 0.0266 0.0302
Loa Loa (eye worm) carboxylesterase 0.0046 0.0088 0.0099
Trichomonas vaginalis penicillin-binding protein, putative 0.0118 0.0339 0.1653
Echinococcus granulosus lysine specific histone demethylase 1A 0.0041 0.0072 0.007
Onchocerca volvulus 0.0097 0.0266 0.1235
Mycobacterium ulcerans aldehyde dehydrogenase 0.0059 0.0134 0.0585
Schistosoma mansoni muscarinic acetylcholine (GAR) receptor 0.0412 0.1363 0.1361
Brugia malayi beta-lactamase 0.0118 0.0339 0.0388
Brugia malayi RNA, U transporter 1 0.0081 0.021 0.0241
Schistosoma mansoni alkaline phosphatase 0.0319 0.1041 0.1039
Echinococcus granulosus polycomb protein SCMH1 0.0051 0.0105 0.0103
Brugia malayi hypothetical protein 0.0412 0.1363 0.156
Brugia malayi mbt repeat family protein 0.0051 0.0105 0.012
Loa Loa (eye worm) hypothetical protein 0.0412 0.1363 0.1558
Loa Loa (eye worm) hypothetical protein 0.0097 0.0266 0.0302
Echinococcus multilocularis nicotinic acetylcholine receptor a11 subunit 0.008 0.0206 0.0204
Loa Loa (eye worm) hypothetical protein 0.0157 0.0475 0.0542
Loa Loa (eye worm) hypothetical protein 0.0046 0.0088 0.0099
Echinococcus granulosus intestinal type alkaline phosphatase 0.0319 0.1041 0.1039
Loa Loa (eye worm) hypothetical protein 0.0037 0.0057 0.0063
Plasmodium vivax lysine-specific histone demethylase 1, putative 0.0041 0.0072 0.2087
Echinococcus multilocularis polycomb protein SCMH1 0.0051 0.0105 0.0103
Chlamydia trachomatis arginine ABC transporter substrate-binding protein ArtJ 0.0132 0.039 1
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0118 0.0339 0.0337
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0107 0.0301 0.1468
Mycobacterium ulcerans pyruvate kinase 0.0068 0.0164 0.0736
Plasmodium falciparum transporter, putative 0.0105 0.0295 1
Brugia malayi Dopamine receptor protein 2 0.0412 0.1363 0.156
Loa Loa (eye worm) hypothetical protein 0.008 0.0206 0.0234
Loa Loa (eye worm) hypothetical protein 0.0027 0.0022 0.0023
Brugia malayi gonadotropin-releasing hormone receptor 2 0.0412 0.1363 0.156
Echinococcus multilocularis nicotinic acetylcholine receptor subunit type 0.0037 0.0057 0.0055
Echinococcus granulosus gamma aminobutyric acid receptor subunit 0.0037 0.0057 0.0055
Loa Loa (eye worm) GABA receptor subunit 0.0043 0.0078 0.0087
Brugia malayi C2-HC type zinc finger protein C.e-MyT1 0.0058 0.0129 0.0148
Echinococcus multilocularis G protein coupled receptor 139 0.0412 0.1363 0.1361
Schistosoma mansoni biogenic amine (5HT) receptor 0.0778 0.2637 0.2636
Toxoplasma gondii glycosyl hydrolase, family 31 protein 0.0071 0.0177 0.3299
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0027 0.0021 0.0095
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.0098 0.0271 0.027
Onchocerca volvulus 0.0097 0.0266 0.1235
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0412 0.1363 0.1361
Plasmodium falciparum pyruvate kinase 2 0.0035 0.005 0.1635
Mycobacterium tuberculosis Probable short-chain type dehydrogenase/reductase 0.0058 0.013 0.0455
Loa Loa (eye worm) solute carrier family 6 member 4 0.062 0.2085 0.2386
Echinococcus granulosus TWiK family of potassium channels protein 7 0.0097 0.0266 0.0264
Schistosoma mansoni neuropeptide receptor 0.0412 0.1363 0.1361
Loa Loa (eye worm) hypothetical protein 0.0041 0.0072 0.0081
Loa Loa (eye worm) hypothetical protein 0.0097 0.0266 0.0302
Brugia malayi Pre-SET motif family protein 0.0065 0.0154 0.0176
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0026 0.0019 0.0033
Plasmodium vivax hypothetical protein, conserved 0.0041 0.0072 0.2087
Mycobacterium tuberculosis Carboxylesterase LipT 0.0046 0.0088 0.0288
Loa Loa (eye worm) nicotinic acetylcholine receptor alpha subunit 0.008 0.0206 0.0234
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0412 0.1363 0.1361
Entamoeba histolytica exodeoxyribonuclease III, putative 0.0098 0.0271 0.2109
Loa Loa (eye worm) hypothetical protein 0.0043 0.0078 0.0087
Echinococcus multilocularis CAAX prenyl protease 2 0.0181 0.0558 0.0557
Mycobacterium tuberculosis Probable hydrolase 0.0118 0.0339 0.1279
Schistosoma mansoni neuropeptide receptor 0.0412 0.1363 0.1361
Trichomonas vaginalis pyruvate kinase, putative 0.0068 0.0164 0.0796
Loa Loa (eye worm) hypothetical protein 0.0097 0.0266 0.0302
Schistosoma mansoni calcium-activated potassium channel 0.0097 0.0266 0.0264
Schistosoma mansoni twik family of potassium channels-related 0.0097 0.0266 0.0264
Onchocerca volvulus 0.0501 0.1671 0.8006
Brugia malayi DnaJ domain containing protein 0.006 0.0138 0.0158
Loa Loa (eye worm) hypothetical protein 0.0046 0.0088 0.0099
Plasmodium vivax AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0098 0.0271 0.7996
Plasmodium vivax SET domain protein, putative 0.0065 0.0154 0.4518
Schistosoma mansoni twik family of potassium channels-related 0.0097 0.0266 0.0264
Loa Loa (eye worm) hypothetical protein 0.008 0.0206 0.0234
Echinococcus granulosus potassium channel subfamily K 8 0.0097 0.0266 0.0264
Schistosoma mansoni metabotropic glutamate receptor 0.0026 0.0021 0.0019
Echinococcus granulosus hypothetical protein 0.0412 0.1363 0.1361
Loa Loa (eye worm) hypothetical protein 0.0412 0.1363 0.1558
Onchocerca volvulus 0.0046 0.0088 0.038
Brugia malayi hypothetical protein 0.0412 0.1363 0.156
Echinococcus granulosus nmda type glutamate receptor 0.0184 0.0569 0.0568
Onchocerca volvulus 0.0037 0.0057 0.0228
Schistosoma mansoni twik family of potassium channels-related 0.0097 0.0266 0.0264
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0306 0.0993 0.4854
Brugia malayi MH1 domain containing protein 0.0029 0.0028 0.0032
Trichomonas vaginalis alpha-glucosidase, putative 0.0071 0.0177 0.0857
Echinococcus granulosus serotonin receptor 0.0412 0.1363 0.1361
Echinococcus multilocularis orexin receptor type 2 0.0412 0.1363 0.1361
Trypanosoma cruzi apurinic/apyrimidinic endonuclease 0.0098 0.0271 0.0524
Schistosoma mansoni intermediate filament proteins 0.0114 0.0327 0.0325
Brugia malayi Twik (KCNK-like) family of potassium channels, alpha subunit 21 0.0097 0.0266 0.0304
Onchocerca volvulus 0.0093 0.0253 0.1172
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0059 0.0134 0.0256
Echinococcus granulosus calcium activated potassium channel variant 0.0097 0.0266 0.0264
Trichomonas vaginalis glucosylceramidase, putative 0.0197 0.0613 0.2996
Loa Loa (eye worm) CMGC/MAPK/ERK1 protein kinase 0.0059 0.0134 0.0151
Brugia malayi Twik (KCNK-like) family of potassium channels, alpha subunit 39A 0.0097 0.0266 0.0304
Trypanosoma cruzi glycosyl hydrolase-like protein, putative 0.0027 0.0021 0.0038
Echinococcus granulosus rhodopsin orphan GPCR 0.0412 0.1363 0.1361
Mycobacterium tuberculosis Probable cytochrome P450 monooxygenase 142 Cyp142 0.004 0.0067 0.0207
Onchocerca volvulus 0.0043 0.0078 0.0332
Echinococcus granulosus sodium:glucose cotransporter 2 0.0038 0.006 0.0058
Echinococcus granulosus growth hormone secretagogue receptor type 1 0.0412 0.1363 0.1361
Loa Loa (eye worm) hypothetical protein 0.0105 0.0295 0.0336
Leishmania major pyruvate kinase 0.0068 0.0164 0.0316
Loa Loa (eye worm) excitatory GABA receptor EXP-1A 0.008 0.0206 0.0234
Schistosoma mansoni hypothetical protein 0.1436 0.4929 0.4928
Schistosoma mansoni alpha-glucosidase 0.0276 0.089 0.0888
Loa Loa (eye worm) hypothetical protein 0.0026 0.0021 0.0022
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0185 0.0573 0.0572
Loa Loa (eye worm) hypothetical protein 0.0026 0.0021 0.0022
Echinococcus granulosus pyruvate kinase 0.0035 0.005 0.0048
Schistosoma mansoni inositol transporter 0.0038 0.006 0.0058
Plasmodium vivax ataxin-2 like protein, putative 0.0027 0.0022 0.0595
Brugia malayi acetylcholine receptor alpha subunit precursor, putative 0.008 0.0206 0.0236
Echinococcus multilocularis lamin dm0 0.0114 0.0327 0.0325
Onchocerca volvulus 0.0026 0.0021 0.0057
Plasmodium falciparum flap endonuclease 1 0.0028 0.0025 0.079
Echinococcus granulosus thioredoxin glutathione reductase 0.0075 0.0191 0.019
Brugia malayi Glycosyl hydrolases family 31 protein 0.0027 0.0021 0.0024
Trypanosoma cruzi mitogen activated protein kinase 4, putative 0.0059 0.0134 0.0256
Loa Loa (eye worm) hypothetical protein 0.0097 0.0266 0.0302
Trichomonas vaginalis glucosylceramidase, putative 0.0187 0.0578 0.2825
Leishmania major C-14 sterol reductase, putative 0.0093 0.0251 0.0485
Echinococcus granulosus potassium voltage gated channel subfamily H 0.0078 0.02 0.0199
Loa Loa (eye worm) hypothetical protein 0.008 0.0206 0.0234
Toxoplasma gondii aldehyde dehydrogenase 0.0059 0.0134 0.2487
Mycobacterium ulcerans glutamine-binding lipoprotein GlnH 0.0132 0.039 0.1847
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.0118 0.0339 0.1279
Brugia malayi Glutamate receptor 1 precursor 0.0052 0.0109 0.0124
Loa Loa (eye worm) G-protein coupled receptor 0.0412 0.1363 0.1558
Brugia malayi hypothetical protein 0.0037 0.0057 0.0065
Schistosoma mansoni hypothetical protein 0.0097 0.0266 0.0264
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative 0.0098 0.0271 0.0524
Brugia malayi Smad1 0.0052 0.0109 0.0124
Schistosoma mansoni voltage-gated potassium channel 0.0023 0.0007 0.0006
Echinococcus granulosus geminin 0.1436 0.4929 0.4928
Mycobacterium tuberculosis Probable reductase 0.017 0.052 0.1993
Echinococcus granulosus g protein coupled receptor 0.0412 0.1363 0.1361
Echinococcus multilocularis sodium and chloride dependent glycine 0.0105 0.0295 0.0293
Trichomonas vaginalis flap endonuclease-1, putative 0.0028 0.0025 0.0113
Schistosoma mansoni scm-relatedprotein containing 4 mbt domains (sfmbt) 0.0051 0.0105 0.0103
Loa Loa (eye worm) beta-lactamase 0.0118 0.0339 0.0386
Giardia lamblia Fructose-bisphosphate aldolase 0.0306 0.0993 0.7745
Echinococcus granulosus Transcription factor JmjC domain containing protein 0.0062 0.0146 0.0144
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0049 0.0099 0.0097
Leishmania major potassium channel subunit-like protein 0.0097 0.0266 0.0513
Echinococcus granulosus alpha 1A adrenergic receptor 0.0412 0.1363 0.1361
Echinococcus multilocularis L aminoadipate semialdehyde 0.0088 0.0235 0.0233
Echinococcus granulosus glycine receptor subunit alpha 1 0.008 0.0206 0.0204
Schistosoma mansoni serine/threonine protein kinase 0.0059 0.0134 0.0132
Loa Loa (eye worm) hypothetical protein 0.008 0.0206 0.0234
Echinococcus multilocularis sex peptide receptor 0.0412 0.1363 0.1361
Loa Loa (eye worm) hypothetical protein 0.008 0.0206 0.0234
Brugia malayi nicotinic acetylcholine receptor alpha subunit, putative 0.008 0.0206 0.0236
Loa Loa (eye worm) intermediate filament protein 0.0114 0.0327 0.0372
Trypanosoma brucei importin beta-1 subunit, putative 0.0028 0.0028 0.0051
Brugia malayi Twik (KCNK-like) family of potassium channels, alpha subunit 32 0.0097 0.0266 0.0304
Echinococcus multilocularis g protein coupled receptor 0.0412 0.1363 0.1361
Onchocerca volvulus 0.0412 0.1363 0.6518
Echinococcus multilocularis suppression of tumorigenicity 18 protein 0.0058 0.0129 0.0127
Loa Loa (eye worm) glutathione reductase 0.0074 0.0188 0.0213
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0065 0.0154 0.0152
Echinococcus multilocularis Glutamate receptor, ionotropic kainate 2 0.0078 0.0201 0.0199
Schistosoma mansoni glutamate receptor AMPA 0.0052 0.0109 0.0107
Loa Loa (eye worm) hypothetical protein 0.0043 0.0078 0.0087
Entamoeba histolytica hypothetical protein 0.0076 0.0193 0.1494
Echinococcus granulosus lamin dm0 0.0114 0.0327 0.0325
Schistosoma mansoni thyrotropin-releasing hormone receptor 0.0412 0.1363 0.1361
Echinococcus granulosus neuropeptide receptor A26 0.0412 0.1363 0.1361
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0195 0.0606 0.0692
Trichomonas vaginalis ap endonuclease, putative 0.0098 0.0271 0.1321
Loa Loa (eye worm) hypothetical protein 0.0037 0.0057 0.0063
Echinococcus multilocularis Cys loop ligand gated ion channel subunit 0.008 0.0206 0.0204
Loa Loa (eye worm) hypothetical protein 0.0412 0.1363 0.1558
Plasmodium falciparum amino acid transporter, putative 0.0105 0.0295 1
Loa Loa (eye worm) hypothetical protein 0.0105 0.0295 0.0336
Onchocerca volvulus 0.0065 0.0154 0.0698
Brugia malayi hypothetical protein 0.0412 0.1363 0.156
Trichomonas vaginalis esterase, putative 0.0118 0.0339 0.1653
Echinococcus multilocularis tyrosine kinase 0.0026 0.0021 0.0019
Brugia malayi Twik (KCNK-like) family of potasium channels, alpha subunit 40 0.0097 0.0266 0.0304
Loa Loa (eye worm) hypothetical protein 0.0097 0.0266 0.0302
Echinococcus multilocularis sodium dependent neurotransmitter transporter 0.0105 0.0295 0.0293
Giardia lamblia NADH oxidase lateral transfer candidate 0.0026 0.0019 0.0132
Loa Loa (eye worm) hypothetical protein 0.0412 0.1363 0.1558
Loa Loa (eye worm) neuronal acetylcholine receptor protein 0.0037 0.0057 0.0063
Trypanosoma cruzi NADH-ubiquinone oxidoreductase, mitochondrial, putative 0.0157 0.0476 0.0922
Toxoplasma gondii Sodium:neurotransmitter symporter family protein 0.0105 0.0295 0.553
Schistosoma mansoni sodium/solute symporter 0.0038 0.006 0.0058
Plasmodium vivax flap endonuclease 1, putative 0.0028 0.0025 0.0686
Trichomonas vaginalis protein kinase inhibitor, putative 0.006 0.0138 0.0668
Loa Loa (eye worm) DnaJ domain-containing protein 0.006 0.0138 0.0156
Echinococcus multilocularis lysine specific demethylase 5A 0.0062 0.0146 0.0144
Loa Loa (eye worm) hypothetical protein 0.0118 0.0339 0.0386
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0412 0.1363 0.1361
Trypanosoma brucei pyruvate kinase 1 0.0068 0.0164 0.0316
Mycobacterium tuberculosis Conserved protein 0.0118 0.0339 0.1279
Echinococcus multilocularis mixed lineage leukemia protein mll 0.0024 0.0011 0.001
Echinococcus granulosus fmrfamide receptor 0.0412 0.1363 0.1361
Loa Loa (eye worm) hypothetical protein 0.0118 0.0339 0.0386
Trichomonas vaginalis glucosylceramidase, putative 0.0284 0.0919 0.4493
Plasmodium vivax potassium channel, putative 0.0097 0.0266 0.7822
Brugia malayi Carboxylesterase family protein 0.0271 0.0871 0.0997
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.017 0.0519 0.2536
Brugia malayi hypothetical protein 0.0037 0.0057 0.0065
Loa Loa (eye worm) acetylcholine receptor protein 0.0037 0.0057 0.0063
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0118 0.0339 0.0386
Mycobacterium leprae Probable fructose bisphosphate aldolase Fba 0.0149 0.0449 0.759
Brugia malayi Sodium:solute symporter family protein 0.0038 0.006 0.0068
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.2549 0.8801 0.8801
Echinococcus multilocularis Ribosomal protein S1, RNA binding domain 0.0052 0.0109 0.0107
Loa Loa (eye worm) hypothetical protein 0.008 0.0206 0.0234
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0412 0.1363 0.1361
Loa Loa (eye worm) hypothetical protein 0.0097 0.0266 0.0302
Mycobacterium tuberculosis Probable cytochrome P450 124 Cyp124 0.004 0.0067 0.0207
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0029 0.003 0.0028
Giardia lamblia Pyruvate kinase 0.0035 0.005 0.0375
Schistosoma mansoni glutamate receptor NMDA 0.0078 0.0201 0.0199
Echinococcus granulosus potassium channel subfamily K 8 0.0097 0.0266 0.0264
Echinococcus granulosus mothers against decapentaplegic 5 0.0052 0.0109 0.0107
Schistosoma mansoni caspase-7 (C14 family) 0.0095 0.026 0.0258
Mycobacterium ulcerans hypothetical protein 0.0118 0.0339 0.1598
Loa Loa (eye worm) ligand-Gated ion Channel family member 0.008 0.0206 0.0234
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.008 0.0206 0.0236
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0412 0.1363 0.1361
Trichomonas vaginalis D-aminoacylase, putative 0.0118 0.0339 0.1653
Echinococcus multilocularis TWiK family of potassium channels protein 7 0.0097 0.0266 0.0264
Echinococcus granulosus neuropeptide receptor 0.0412 0.1363 0.1361
Mycobacterium tuberculosis Probable pyruvate kinase PykA 0.0068 0.0164 0.0589
Loa Loa (eye worm) hypothetical protein 0.0412 0.1363 0.1558
Mycobacterium ulcerans cytochrome P450 185A4 Cyp185A4 0.0066 0.016 0.0716
Loa Loa (eye worm) cytochrome P450 0.004 0.0067 0.0075
Schistosoma mansoni jumonji/arid domain-containing protein 0.0067 0.0163 0.0161
Loa Loa (eye worm) hypothetical protein 0.0043 0.0078 0.0087
Loa Loa (eye worm) hypothetical protein 0.0097 0.0266 0.0302
Onchocerca volvulus Pyruvate kinase homolog 0.0068 0.0164 0.0747
Onchocerca volvulus Neuropeptide F receptor homolog 0.0412 0.1363 0.6518
Plasmodium falciparum potassium channel 0.0097 0.0266 0.9002
Echinococcus granulosus nmda type glutamate receptor 0.0026 0.0021 0.0019
Schistosoma mansoni pyruvate kinase 0.0068 0.0164 0.0163
Schistosoma mansoni neuropeptide F-like receptor 0.0412 0.1363 0.1361
Schistosoma mansoni lamin 0.0114 0.0327 0.0325
Trichomonas vaginalis ap endonuclease, putative 0.0098 0.0271 0.1321
Echinococcus multilocularis neuropeptide receptor 0.0412 0.1363 0.1361
Brugia malayi putative neuropeptide receptor NPR1 0.0412 0.1363 0.156
Loa Loa (eye worm) cytoplasmic intermediate filament protein 0.0061 0.0142 0.0161
Brugia malayi hypothetical protein 0.0412 0.1363 0.156
Mycobacterium ulcerans cytochrome P450 143A3 Cyp143A3 0.004 0.0067 0.0259
Echinococcus granulosus tachykinin peptides receptor 99D 0.0412 0.1363 0.1361
Trypanosoma brucei mitogen activated protein kinase 4, putative 0.0059 0.0134 0.0256
Loa Loa (eye worm) hypothetical protein 0.0097 0.0266 0.0302
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0306 0.0993 0.4854
Trypanosoma cruzi PAB1-binding protein , putative 0.0027 0.0022 0.0039
Echinococcus granulosus metabotropic glutamate receptor 2 0.0026 0.0021 0.0019
Loa Loa (eye worm) hypothetical protein 0.0093 0.0253 0.0287
Brugia malayi G-protein-linked acetylcholine receptor protein 2, putative 0.0412 0.1363 0.156
Echinococcus multilocularis rhodopsin orphan GPCR 0.0412 0.1363 0.1361
Loa Loa (eye worm) acetyltransferase 0.031 0.1007 0.1151
Schistosoma mansoni nAChR subunit (ShAR1-alpha-like) 0.008 0.0206 0.0204
Schistosoma mansoni biogenic amine (5HT) receptor 0.1279 0.438 0.4379
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0023 0.0009 0.0036
Echinococcus multilocularis glycine receptor subunit alpha 1 0.008 0.0206 0.0204
Brugia malayi G-protein coupled receptor 0.0412 0.1363 0.156
Brugia malayi Neurotransmitter-gated ion-channel transmembrane region family protein 0.0043 0.0078 0.0089
Toxoplasma gondii flap structure-specific endonuclease 1, putative 0.0028 0.0025 0.0437
Onchocerca volvulus Atrial natriuretic peptide receptor 3 homolog 0.0026 0.0021 0.0057
Trichomonas vaginalis glucosylceramidase, putative 0.0284 0.0919 0.4493
Echinococcus granulosus SAM and MBT domain containing protein 0.0051 0.0105 0.0103
Echinococcus granulosus G protein coupled receptor 139 0.0412 0.1363 0.1361
Onchocerca volvulus Polycomb protein Sfmbt homolog 0.0051 0.0105 0.046
Echinococcus multilocularis potassium channel subfamily K 8 0.0097 0.0266 0.0264
Trichomonas vaginalis CMGC family protein kinase 0.0059 0.0134 0.0646
Brugia malayi hypothetical protein 0.0037 0.0057 0.0065
Schistosoma mansoni twik family of potassium channels-related 0.0097 0.0266 0.0264
Mycobacterium tuberculosis Probable membrane NADH dehydrogenase NdhA 0.017 0.052 0.1993
Onchocerca volvulus 0.0046 0.0088 0.038
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0412 0.1363 0.1361
Schistosoma mansoni peptide (FMRFamide/neurokinin-3)-like receptor 0.0412 0.1363 0.1361
Echinococcus multilocularis potassium voltage gated channel subfamily H 0.0078 0.02 0.0199
Onchocerca volvulus 0.0412 0.1363 0.6518
Mycobacterium tuberculosis Probable aldehyde dehydrogenase 0.0059 0.0134 0.0468
Echinococcus multilocularis alpha 1A adrenergic receptor 0.0412 0.1363 0.1361
Echinococcus granulosus dnaJ subfamily B 0.1228 0.4204 0.4203
Loa Loa (eye worm) glutamate-gated chloride channel alpha3A subunit 0.0037 0.0057 0.0063
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0093 0.0253 0.0251
Onchocerca volvulus 0.0097 0.0266 0.1235
Onchocerca volvulus 0.0037 0.0057 0.0228
Schistosoma mansoni alpha-glucosidase 0.0276 0.089 0.0888
Loa Loa (eye worm) hypothetical protein 0.0026 0.0021 0.0022
Trypanosoma cruzi UDP-galactopyranose mutase 0.0041 0.0072 0.0137
Trypanosoma brucei C-14 sterol reductase, putative 0.0093 0.0251 0.0485
Loa Loa (eye worm) hypothetical protein 0.0097 0.0266 0.0302
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0058 0.013 0.0568
Mycobacterium tuberculosis Probable NADH dehydrogenase Ndh 0.017 0.052 0.1993
Trypanosoma brucei PAB1-binding protein , putative 0.0027 0.0022 0.0039
Schistosoma mansoni alkaline phosphatase 0.0319 0.1041 0.1039
Loa Loa (eye worm) hypothetical protein 0.0037 0.0057 0.0063
Schistosoma mansoni glutamate receptor kainate 0.0052 0.0109 0.0107
Mycobacterium tuberculosis Conserved protein 0.0118 0.0339 0.1279
Schistosoma mansoni nAChR subunit 0.008 0.0206 0.0204
Loa Loa (eye worm) G-protein coupled receptor 0.0412 0.1363 0.1558
Onchocerca volvulus 0.0105 0.0295 0.1376
Echinococcus granulosus family S9 non peptidase ue S09 family 0.0046 0.0088 0.0086
Trypanosoma brucei importin beta-1 subunit, putative 0.0028 0.0028 0.0051
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.008 0.0206 0.0236
Mycobacterium tuberculosis Conserved hypothetical protein 0.0041 0.0072 0.0226
Mycobacterium ulcerans NADH dehydrogenase I subunit F 0.0157 0.0476 0.2274
Schistosoma mansoni hypothetical protein 0.0049 0.0099 0.0097
Echinococcus granulosus g protein coupled receptor 0.0412 0.1363 0.1361
Echinococcus granulosus acetylcholinesterase 0.0271 0.0871 0.087
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0037 0.0057 0.0065
Loa Loa (eye worm) hypothetical protein 0.0412 0.1363 0.1558
Loa Loa (eye worm) hypothetical protein 0.0043 0.0078 0.0087
Mycobacterium ulcerans cytochrome P450 144A4 Cyp144A4 0.004 0.0067 0.0259
Brugia malayi hypothetical protein 0.0037 0.0057 0.0065
Schistosoma mansoni hypothetical protein 0.0049 0.0099 0.0097
Schistosoma mansoni tyrosine kinase 0.0026 0.0021 0.0019
Schistosoma mansoni importin beta-1 0.0028 0.0028 0.0026
Loa Loa (eye worm) hypothetical protein 0.0088 0.0235 0.0267
Loa Loa (eye worm) hypothetical protein 0.0097 0.0266 0.0302
Loa Loa (eye worm) hypothetical protein 0.0118 0.0339 0.0386
Mycobacterium leprae Probable lipase LipE 0.0118 0.0339 0.5675
Echinococcus granulosus lamin 0.0114 0.0327 0.0325
Giardia lamblia Hypothetical protein 0.0097 0.0266 0.2063
Loa Loa (eye worm) voltage and ligand gated potassium channel 0.0078 0.02 0.0228
Echinococcus multilocularis tachykinin peptides receptor 99D 0.0412 0.1363 0.1361
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.0098 0.0271 0.0309
Echinococcus multilocularis rhodopsin orphan GPCR 0.0412 0.1363 0.1361
Loa Loa (eye worm) hypothetical protein 0.0043 0.0078 0.0087
Treponema pallidum hypothetical protein 0.0037 0.0059 0.0211
Onchocerca volvulus 0.0118 0.0339 0.1589
Schistosoma mansoni ap endonuclease 0.0098 0.0271 0.027
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0412 0.1363 0.1361
Trypanosoma brucei calcium-activated potassium channel, putative 0.0097 0.0266 0.0513
Echinococcus granulosus beta LACTamase domain containing family member 0.0118 0.0339 0.0337
Loa Loa (eye worm) acetylcholinesterase 1 0.0271 0.0871 0.0996
Schistosoma mansoni hypothetical protein 0.0304 0.0986 0.0985
Mycobacterium leprae conserved hypothetical protein 0.0118 0.0339 0.5675
Echinococcus granulosus receptor type guanylyl cyclase 0.0026 0.0021 0.0019
Brugia malayi Guanylyl cyclase protein 23 0.0026 0.0021 0.0024
Onchocerca volvulus 0.0412 0.1363 0.6518
Echinococcus granulosus mitogen activated protein kinase 3 0.0059 0.0134 0.0132
Wolbachia endosymbiont of Brugia malayi NADH dehydrogenase I subunit F 0.0157 0.0476 1
Schistosoma mansoni opsin-like receptor 0.0412 0.1363 0.1361
Brugia malayi Acetylcholine receptor protein, alpha-like chain 1 precursor 0.0037 0.0057 0.0065
Schistosoma mansoni acetylcholine receptor-related 0.0037 0.0057 0.0055
Loa Loa (eye worm) hypothetical protein 0.1279 0.438 0.5014
Echinococcus granulosus rhodopsin orphan GPCR 0.0412 0.1363 0.1361
Echinococcus multilocularis glutamate receptor, ionotrophic, AMPA 3 0.0078 0.0201 0.0199
Trypanosoma cruzi mitogen activated protein kinase 2, putative 0.0059 0.0134 0.0256
Mycobacterium tuberculosis Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) 0.0098 0.0271 0.1012
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0026 0.0019 0.0033
Mycobacterium ulcerans cytochrome P450 191A3 Cyp191A3 0.004 0.0067 0.0259
Trichomonas vaginalis CMGC family protein kinase 0.0059 0.0134 0.0646
Onchocerca volvulus 0.0412 0.1363 0.6518
Schistosoma mansoni sodium-dependent neurotransmitter transporter 0.0105 0.0295 0.0293
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0037 0.0057 0.0065
Loa Loa (eye worm) hypothetical protein 0.008 0.0206 0.0234
Mycobacterium ulcerans cytochrome P450 188A3 Cyp188A3 0.004 0.0067 0.0259
Schistosoma mansoni family S9 non-peptidase homologue (S09 family) 0.0046 0.0088 0.0086
Schistosoma mansoni cpg binding protein 0.0091 0.0246 0.0244
Entamoeba histolytica pyruvate kinase, putative 0.0047 0.0093 0.0714
Loa Loa (eye worm) hypothetical protein 0.0047 0.0093 0.0105
Brugia malayi Carboxylesterase family protein 0.0046 0.0088 0.0101
Loa Loa (eye worm) pyruvate kinase 0.0068 0.0164 0.0186
Schistosoma mansoni biogenic amine receptor 0.0412 0.1363 0.1361
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0049 0.0099 0.0097
Brugia malayi Cytochrome P450 family protein 0.0066 0.016 0.0183
Loa Loa (eye worm) hypothetical protein 0.0412 0.1363 0.1558
Loa Loa (eye worm) hypothetical protein 0.008 0.0206 0.0234
Entamoeba histolytica glycosyl hydrolase, family 31 protein 0.0027 0.0021 0.0151
Schistosoma mansoni Smad4 0.0052 0.0109 0.0107
Loa Loa (eye worm) hypothetical protein 0.013 0.038 0.0433
Giardia lamblia Pyruvate kinase 0.0068 0.0164 0.127
Toxoplasma gondii histone lysine methyltransferase SET1 0.0173 0.0532 1
Brugia malayi Twik (KCNK-like) family of potassium channels, alpha subunit 30. 0.0097 0.0266 0.0304
Echinococcus multilocularis nAChR subunit 0.008 0.0206 0.0204
Toxoplasma gondii pyruvate kinase PyKII 0.0035 0.005 0.0904
Onchocerca volvulus 0.032 0.1044 0.4982
Leishmania major sterol C-24 reductase, putative 0.0093 0.0251 0.0485
Echinococcus multilocularis sodium and chloride dependent glycine 0.0105 0.0295 0.0293
Echinococcus granulosus CAAX prenyl protease 2 0.0181 0.0558 0.0557
Onchocerca volvulus Uncharacterized family 31 glucosidase KIAA1161 homolog 0.0027 0.0021 0.0057
Echinococcus multilocularis dnaJ subfamily C 6 0.006 0.0138 0.0137
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0412 0.1363 0.1361
Echinococcus granulosus tyrosine kinase 0.0026 0.0021 0.0019
Echinococcus granulosus cpg binding protein 0.0091 0.0246 0.0244
Schistosoma mansoni neuropeptide F-like receptor 0.0412 0.1363 0.1361
Loa Loa (eye worm) hypothetical protein 0.0995 0.3393 0.3883
Mycobacterium tuberculosis Possible penicillin-binding protein 0.0753 0.255 1
Brugia malayi hypothetical protein 0.032 0.1044 0.1195
Mycobacterium tuberculosis Conserved protein 0.0118 0.0339 0.1279
Loa Loa (eye worm) hypothetical protein 0.0412 0.1363 0.1558
Echinococcus granulosus atrial natriuretic peptide receptor 0.0026 0.0021 0.0019
Mycobacterium tuberculosis Probable conserved lipoprotein 0.0118 0.0339 0.1279
Brugia malayi Carboxylesterase family protein 0.0046 0.0088 0.0101
Brugia malayi Carboxylesterase family protein 0.0271 0.0871 0.0997
Loa Loa (eye worm) hypothetical protein 0.0097 0.0266 0.0302
Loa Loa (eye worm) hypothetical protein 0.0244 0.0778 0.0889
Trichomonas vaginalis maltase-glucoamylase, putative 0.0071 0.0177 0.0857
Brugia malayi Hypothetical glycine receptor like protein T20B12.9 in chromosome III 0.0043 0.0078 0.0089
Echinococcus multilocularis flap endonuclease 1 0.0028 0.0025 0.0023
Onchocerca volvulus 0.0086 0.0229 0.1058
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.0118 0.0339 0.1598
Echinococcus multilocularis Glutamate receptor, ionotropic kainate 2 0.0078 0.0201 0.0199
Brugia malayi Hypothetical glycine receptor like protein T20B12.9 in chromosome III 0.008 0.0206 0.0236
Brugia malayi Twik (KCNK-like) family of potassium channels, alpha subunit 45 0.0097 0.0266 0.0304
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0107 0.0301 0.1468
Echinococcus multilocularis glycine receptor subunit alpha 1 0.008 0.0206 0.0204
Loa Loa (eye worm) hypothetical protein 0.0118 0.0339 0.0386
Loa Loa (eye worm) hypothetical protein 0.0026 0.0021 0.0022
Loa Loa (eye worm) hypothetical protein 0.0412 0.1363 0.1558
Brugia malayi Cation transporter family protein 0.008 0.0206 0.0236
Brugia malayi Thioredoxin reductase 0.0074 0.0188 0.0215
Echinococcus granulosus sodium dependent neurotransmitter transporter 0.0105 0.0295 0.0293
Loa Loa (eye worm) gonadotropin-releasing hormone receptor 2 0.0412 0.1363 0.1558
Schistosoma mansoni norepinephrine/norepinephrine transporter 0.0105 0.0295 0.0293
Echinococcus multilocularis nicotinic acetylcholine receptor alpha subunit 0.008 0.0206 0.0204
Loa Loa (eye worm) hypothetical protein 0.0028 0.0028 0.003
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.008 0.0206 0.0236
Schistosoma mansoni 3-hydroxyacyl-CoA dehydrogenase 0.0058 0.013 0.0129
Onchocerca volvulus 0.008 0.0206 0.0947
Mycobacterium tuberculosis Probable cytochrome P450 140 Cyp140 0.004 0.0067 0.0207
Loa Loa (eye worm) hypothetical protein 0.0271 0.0871 0.0996
Echinococcus multilocularis g-protein coupled receptor 0.0412 0.1363 0.1361
Echinococcus multilocularis smad 0.0052 0.0109 0.0107
Loa Loa (eye worm) hypothetical protein 0.0097 0.0266 0.0302
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0306 0.0993 0.4854
Brugia malayi acetyltransferase, GNAT family protein 0.031 0.1007 0.1152
Echinococcus granulosus glutamate receptor 2 0.0026 0.0021 0.0019
Echinococcus multilocularis neuropeptides capa receptor 0.0412 0.1363 0.1361
Loa Loa (eye worm) glutamate receptor 2 0.0052 0.0109 0.0122
Loa Loa (eye worm) hypothetical protein 0.1499 0.5148 0.5892
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0412 0.1363 0.1361
Loa Loa (eye worm) follicle stimulating hormone receptor 0.0638 0.2149 0.2458
Leishmania major C-8 sterol isomerase-like protein 0.1499 0.5148 1
Trypanosoma brucei glycosyl hydrolase-like protein 0.0027 0.0021 0.0038
Loa Loa (eye worm) potassium voltage-gated channel subfamily Q member 5 0.0097 0.0266 0.0302
Brugia malayi MH1 domain containing protein 0.0052 0.0109 0.0124
Loa Loa (eye worm) hypothetical protein 0.0106 0.0296 0.0338
Wolbachia endosymbiont of Brugia malayi dihydrolipoamide dehydrogenase E3 component 0.0026 0.0019 0.008
Brugia malayi Melatonin receptor type 1A 0.0412 0.1363 0.156
Mycobacterium tuberculosis Cytochrome P450 51 Cyp51 (CYPL1) (P450-L1A1) (sterol 14-alpha demethylase) (lanosterol 14-alpha demethylase) (P450-14DM) 0.004 0.0067 0.0207
Trichomonas vaginalis glutathione reductase, putative 0.0026 0.0019 0.0083
Schistosoma mansoni gcn5proteinral control of amino-acid synthesis 5-like 2 gcnl2 0.031 0.1007 0.1005
Trichomonas vaginalis glucosylceramidase, putative 0.0284 0.0919 0.4493
Echinococcus multilocularis neuropeptide receptor A26 0.0412 0.1363 0.1361
Echinococcus multilocularis arachidonate 5 lipoxygenase 0.0056 0.0123 0.0121
Onchocerca volvulus 0.0046 0.0088 0.038
Echinococcus multilocularis g protein coupled receptor 0.0412 0.1363 0.1361
Echinococcus multilocularis neuroligin 0.0046 0.0088 0.0086
Echinococcus granulosus serotonin transporter 0.062 0.2085 0.2084
Trichomonas vaginalis glucosylceramidase, putative 0.0284 0.0919 0.4493
Brugia malayi hypothetical protein 0.0412 0.1363 0.156
Mycobacterium tuberculosis Probable cytochrome P450 139 Cyp139 0.004 0.0067 0.0207
Trypanosoma cruzi CAAX prenyl protease 2, putative 0.0181 0.0558 0.1082
Brugia malayi Flap endonuclease-1 0.0028 0.0025 0.0028
Echinococcus multilocularis sodium:glucose cotransporter 2 0.0038 0.006 0.0058
Brugia malayi Twik (KCNK-like) family of potassium channels, alpha subunit 24 0.0097 0.0266 0.0304
Brugia malayi Twik (KCNK-like) family of potassium channels, alpha subunit 38. C. elegans sup-9 ortholog 0.0097 0.0266 0.0304
Brugia malayi acetylcholine receptor protein, alpha-like chain, putative 0.008 0.0206 0.0236
Brugia malayi Receptor family ligand binding region containing protein 0.0026 0.0021 0.0024
Echinococcus granulosus neuropeptide Y receptor 0.0412 0.1363 0.1361
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0306 0.0993 0.4854
Loa Loa (eye worm) hypothetical protein 0.0412 0.1363 0.1558
Brugia malayi glutamate-gated chloride channel alpha3A subunit, putative 0.0037 0.0057 0.0065
Brugia malayi MH1 domain containing protein 0.0029 0.0028 0.0032
Loa Loa (eye worm) hypothetical protein 0.0027 0.0021 0.0022
Echinococcus multilocularis nmda type glutamate receptor 0.0184 0.0569 0.0568
Trypanosoma cruzi flap endonuclease-1 (FEN-1), putative 0.0028 0.0025 0.0045
Schistosoma mansoni calcium-activated potassium channel 0.0097 0.0266 0.0264
Onchocerca volvulus 0.0412 0.1363 0.6518
Trypanosoma brucei NADH dehydrogenase [ubiquinone] flavoprotein 1, mitochondrial, putative 0.0157 0.0476 0.0922
Echinococcus multilocularis mitogen activated protein kinase 3 0.0059 0.0134 0.0132
Brugia malayi larval opioid receptor 0.0412 0.1363 0.156
Brugia malayi hypothetical protein 0.0412 0.1363 0.156
Brugia malayi MAP kinase sur-1 0.0059 0.0134 0.0153
Loa Loa (eye worm) acetylcholine receptor alpha subunit 0.008 0.0206 0.0234
Schistosoma mansoni hypothetical protein 0.2161 0.745 0.7449
Echinococcus granulosus cytoplasmic intermediate filament protein 0.0055 0.0121 0.0119
Schistosoma mansoni sodium/chloride dependent neurotransmitter transporter 0.0105 0.0295 0.0293
Loa Loa (eye worm) ACC-1 protein 0.008 0.0206 0.0234
Trichomonas vaginalis mercuric reductase, putative 0.0026 0.0019 0.0083
Schistosoma mansoni alpha-1 adrenergic receptor 0.0412 0.1363 0.1361
Echinococcus granulosus potassium channel subfamily K 0.0097 0.0266 0.0264
Toxoplasma gondii hypothetical protein 0.0105 0.0295 0.553
Loa Loa (eye worm) hypothetical protein 0.0412 0.1363 0.1558
Onchocerca volvulus 0.0412 0.1363 0.6518
Mycobacterium ulcerans aldehyde dehydrogenase 0.0059 0.0134 0.0585
Echinococcus granulosus L aminoadipate semialdehyde 0.0088 0.0235 0.0233
Echinococcus multilocularis neuropeptide Y receptor 0.0412 0.1363 0.1361
Echinococcus multilocularis biogenic amine (5HT) receptor 0.0778 0.2637 0.2636
Schistosoma mansoni amine GPCR 0.0412 0.1363 0.1361
Loa Loa (eye worm) hypothetical protein 0.0271 0.0871 0.0996
Loa Loa (eye worm) hypothetical protein 0.0046 0.0088 0.0099
Loa Loa (eye worm) hypothetical protein 0.0027 0.0021 0.0023
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0412 0.1363 0.1361
Wolbachia endosymbiont of Brugia malayi dihydrolipoamide dehydrogenase E3 component 0.0026 0.0019 0.008
Toxoplasma gondii 4'-phosphopantetheinyl transferase domain-containing protein 0.0025 0.0015 0.0249
Echinococcus multilocularis muscleblind protein 1 0.0157 0.0475 0.0473
Mycobacterium tuberculosis Probable integral membrane protein 0.0037 0.0059 0.0173
Plasmodium falciparum protoporphyrinogen oxidase 0.0041 0.0072 0.2402
Loa Loa (eye worm) MH2 domain-containing protein 0.0052 0.0109 0.0122
Echinococcus granulosus dro:myosuppressin receptor 0.0412 0.1363 0.1361
Mycobacterium tuberculosis Probable lipase LipD 0.0118 0.0339 0.1279
Echinococcus multilocularis BC026374 protein (S09 family) 0.0046 0.0088 0.0086
Mycobacterium tuberculosis Probable cytochrome P450 123 Cyp123 0.004 0.0067 0.0207
Echinococcus multilocularis pyruvate kinase 0.0035 0.005 0.0048
Echinococcus multilocularis SAM and MBT domain containing protein 0.0051 0.0105 0.0103
Schistosoma mansoni Cys-loop ligand gated ion channel subunit 0.0043 0.0078 0.0076
Onchocerca volvulus NADH dehydrogenase [ubiquinone] flavoprotein 1, mitochondrial homolog 0.0084 0.0222 0.1026
Toxoplasma gondii hypothetical protein 0.0037 0.0059 0.1075
Schistosoma mansoni histamine h1 receptor 0.0412 0.1363 0.1361
Plasmodium falciparum holo-[acyl-carrier-protein] synthase, putative 0.0025 0.0015 0.0451
Onchocerca volvulus 0.0412 0.1363 0.6518
Echinococcus granulosus pyruvate kinase 0.0068 0.0164 0.0163
Schistosoma mansoni tyrosine kinase 0.0026 0.0021 0.0019
Echinococcus granulosus Two pore potassium channel protein sup 9 0.0097 0.0266 0.0264
Mycobacterium ulcerans dihydrolipoamide dehydrogenase, LpdB 0.0026 0.0019 0.0018
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.008 0.0206 0.0236
Loa Loa (eye worm) glutamate-gated chloride channel alpha3A subunit 0.008 0.0206 0.0234
Loa Loa (eye worm) hypothetical protein 0.0412 0.1363 0.1558
Toxoplasma gondii histone lysine-specific demethylase 0.0041 0.0072 0.1328
Schistosoma mansoni hypothetical protein 0.006 0.0138 0.0137
Loa Loa (eye worm) hypothetical protein 0.0097 0.0266 0.0302
Mycobacterium tuberculosis Probable conserved integral membrane protein 0.0037 0.0059 0.0173
Echinococcus multilocularis nAChR subunit 0.0043 0.0078 0.0076
Trypanosoma cruzi trypanothione reductase, putative 0.0074 0.0188 0.0362
Loa Loa (eye worm) hypothetical protein 0.0076 0.0195 0.0221
Schistosoma mansoni calcium-activated potassium channel 0.2161 0.745 0.7449
Brugia malayi excitatory GABA receptor EXP-1A 0.008 0.0206 0.0236
Loa Loa (eye worm) hypothetical protein 0.0412 0.1363 0.1558
Trypanosoma cruzi cytochrome P450, putative 0.0066 0.016 0.0308
Echinococcus multilocularis mothers against decapentaplegic 2 0.0023 0.0009 0.0007
Loa Loa (eye worm) hypothetical protein 0.0097 0.0266 0.0302
Trypanosoma cruzi hypothetical protein, conserved 0.0097 0.0266 0.0513
Loa Loa (eye worm) glutamate receptor 0.0026 0.0021 0.0022
Giardia lamblia DNA repair protein RAD52 0.0389 0.1281 1
Mycobacterium ulcerans dehydrogenase 0.0041 0.0072 0.0282
Loa Loa (eye worm) pyruvate kinase 0.0068 0.0164 0.0186
Brugia malayi hypothetical protein 0.0105 0.0295 0.0338
Brugia malayi ORL1-like opioid receptor 0.0412 0.1363 0.156
Trypanosoma cruzi UDP-galactopyranose mutase 0.0041 0.0072 0.0137
Mycobacterium ulcerans hypothetical protein 0.0037 0.0059 0.0216
Echinococcus granulosus neuropeptides capa receptor 0.0412 0.1363 0.1361
Echinococcus granulosus glutamate receptor ionotrophic AMPA 3 0.0078 0.0201 0.0199
Brugia malayi Sodium:neurotransmitter symporter family protein 0.062 0.2085 0.2387
Echinococcus granulosus Jumonji AT rich interactive domain 1B 0.0022 0.0004 0.0002
Echinococcus granulosus glycine receptor subunit beta 0.008 0.0206 0.0204
Schistosoma mansoni amine oxidase 0.0041 0.0072 0.007
Brugia malayi latrophilin 2 splice variant baaae 0.0106 0.0296 0.0339
Echinococcus multilocularis rhodopsin orphan GPCR 0.0412 0.1363 0.1361
Onchocerca volvulus 0.0043 0.0078 0.0332
Leishmania major pyruvate kinase 0.0068 0.0164 0.0316
Echinococcus multilocularis neuronal acetylcholine receptor subunit alpha 4 0.008 0.0206 0.0204
Echinococcus multilocularis neuropeptides capa receptor 0.0412 0.1363 0.1361
Schistosoma mansoni voltage-gated potassium channel 0.0085 0.0225 0.0224
Schistosoma mansoni sex comb on midleg homolog 0.0051 0.0105 0.0103
Echinococcus granulosus dihydrolipoamide dehydrogenase 0.0026 0.0019 0.0017
Echinococcus granulosus biogenic amine 5HT receptor 0.1279 0.438 0.4379
Onchocerca volvulus Pyruvate kinase homolog 0.0068 0.0164 0.0747
Schistosoma mansoni amine GPCR 0.0412 0.1363 0.1361
Loa Loa (eye worm) carboxylesterase 0.0271 0.0871 0.0996
Mycobacterium ulcerans ion transport protein 0.0097 0.0266 0.1236
Mycobacterium leprae Conserved hypothetical protein 0.004 0.0067 0.0921
Echinococcus granulosus acetylcholinesterase 0.0271 0.0871 0.087
Brugia malayi CXXC zinc finger family protein 0.0086 0.0229 0.0262
Echinococcus multilocularis sodium:myo inositol cotransporter 0.0038 0.006 0.0058

Activities

Activity type Activity value Assay description Source Reference
Potency (functional) 0.0259 uM PubChem BioAssay. A quantitative high throughput screen for small molecules that induce DNA re-replication in SW480 colon adenocarcinoma cells. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) 4.4668 uM PubChem BioAssay. qHTS for Agonist of gsp, the Etiologic Mutation Responsible for Fibrous Dysplasia/McCune-Albright Syndrome: qHTS. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) 13.1154 uM PUBCHEM_BIOASSAY: Primary qHTS for delayed death inhibitors of the malarial parasite plastid, 96 hour incubation. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID488745, AID488752, AID488774, AID504848, AID504850] ChEMBL. No reference
Potency (functional) 13.1154 uM PUBCHEM_BIOASSAY: Primary qHTS for delayed death inhibitors of the malarial parasite plastid, 48 hour incubation. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID488752, AID488774, AID504848, AID504850] ChEMBL. No reference

Phenotypes

Whole-cell/tissue/organism interactions

Species name Source Reference Is orphan
Plasmodium falciparum ChEMBL23

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

No literature references available for this target.

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