Detailed information for compound 1383064

Basic information

Technical information
  • TDR Targets ID: 1383064
  • Name: 1-(4-phenylphenyl)imidazole
  • MW: 220.269 | Formula: C15H12N2
  • H donors: 0 H acceptors: 1 LogP: 3.3 Rotable bonds: 2
    Rule of 5 violations (Lipinski): 1
  • SMILES: c1ccc(cc1)c1ccc(cc1)n1cncc1
  • InChi: 1S/C15H12N2/c1-2-4-13(5-3-1)14-6-8-15(9-7-14)17-11-10-16-12-17/h1-12H
  • InChiKey: FFRBVGATVOCVAZ-UHFFFAOYSA-N  

Network

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Synonyms

  • MLS000056801
  • SMR000065631
  • ZINC00041747

Targets

Known targets for this compound

Species Target name Source Bibliographic reference
Homo sapiens breast cancer 1, early onset Starlite/ChEMBL No references
Influenza A virus Nonstructural protein 1 Starlite/ChEMBL No references
Caenorhabditis elegans Protein SKN-1, isoform B Starlite/ChEMBL No references
Homo sapiens tumor protein p53 Starlite/ChEMBL No references
Homo sapiens multiple endocrine neoplasia I No references
Homo sapiens arachidonate 15-lipoxygenase Starlite/ChEMBL No references
Escherichia coli penicillin-binding protein Starlite/ChEMBL No references
Homo sapiens nuclear factor, erythroid 2-like 2 Starlite/ChEMBL No references
Homo sapiens ATPase family, AAA domain containing 5 Starlite/ChEMBL No references
Homo sapiens lysine (K)-specific methyltransferase 2A Starlite/ChEMBL No references

Predicted pathogen targets for this compound

By orthology
Species Potential target Known druggable target/s Ortholog Group
Toxoplasma gondii histone lysine methyltransferase SET1 Get druggable targets OG5_130642 All targets in OG5_130642
Schistosoma japonicum ko:K09188 myeloid/lymphoid or mixed-lineage leukemia protein 3, putative Get druggable targets OG5_130642 All targets in OG5_130642
Echinococcus multilocularis atpase aaa+ type core atpase aaa type core Get druggable targets OG5_139225 All targets in OG5_139225
Schistosoma mansoni mixed-lineage leukemia protein mll Get druggable targets OG5_130642 All targets in OG5_130642
Schistosoma japonicum Menin, putative Get druggable targets OG5_133913 All targets in OG5_133913
Neospora caninum Multidomain chromatinic protein with the following architecture: 3x PHD-bromo-3xPHD-SET domain and associated cysteine cluster a Get druggable targets OG5_130642 All targets in OG5_130642
Echinococcus multilocularis dnaJ subfamily B Get druggable targets OG5_133913 All targets in OG5_133913
Echinococcus granulosus tumor protein p63 Get druggable targets OG5_140038 All targets in OG5_140038
Echinococcus multilocularis tumor protein p63 Get druggable targets OG5_140038 All targets in OG5_140038
Mycobacterium tuberculosis Possible penicillin-binding protein Get druggable targets OG5_149948 All targets in OG5_149948
Echinococcus granulosus dnaJ subfamily B Get druggable targets OG5_133913 All targets in OG5_133913
Schistosoma mansoni hypothetical protein Get druggable targets OG5_133913 All targets in OG5_133913

By sequence similarity to non orthologous known druggable targets
Species Potential target Known druggable target Length Alignment span Identity
Echinococcus granulosus arachidonate 5 lipoxygenase arachidonate 15-lipoxygenase 662 aa 590 aa 23.9 %
Mycobacterium tuberculosis Hypothetical protein Nonstructural protein 1   230 aa 202 aa 23.8 %

Obtained from network model

Ranking Plot


Putative Targets List


Species Potential target Raw Global Species
Toxoplasma gondii ATP-dependent Clp endopeptidase, proteolytic subunit ClpP domain-containing protein 0.0024 0.0166 0.0347
Mycobacterium leprae Probable lipase LipE 0.0043 0.0369 0.0787
Trichomonas vaginalis protein farnesyltransferase alpha subunit/RAB geranylgeranyl transferase alpha subunit, putative 0.0053 0.0466 0.3994
Schistosoma mansoni opsin-like receptor 0.0012 0.0047 0.0041
Echinococcus multilocularis 0.0025 0.0184 0.0177
Schistosoma mansoni cellular tumor antigen P53 0.006 0.0536 0.0538
Brugia malayi Protein-tyrosine phosphatase 1 0.0025 0.0184 0.018
Echinococcus multilocularis tachykinin peptides receptor 99D 0.0012 0.0047 0.004
Echinococcus multilocularis dnaJ subfamily B 0.0494 0.5005 0.5002
Brugia malayi Dopamine receptor protein 1, putative (partial) 0.0012 0.0047 0.0041
Brugia malayi beta-lactamase family protein 0.0043 0.0369 0.0368
Echinococcus granulosus protein farnesyltransferase subunit beta 0.001 0.0029 0.0023
Echinococcus granulosus 7tm_1 domain containing protein 0.0012 0.0047 0.0041
Echinococcus multilocularis GTP binding nuclear protein Ran 0.0009 0.0018 0.0012
Schistosoma mansoni L-lactate dehydrogenase 0.0025 0.0181 0.0177
Onchocerca volvulus 0.0025 0.0184 0.2048
Trypanosoma cruzi protein farnesyltransferase alpha subunit, putative 0.0022 0.0152 0.3816
Loa Loa (eye worm) hypothetical protein 0.0025 0.0184 0.018
Toxoplasma gondii poly(ADP-ribose) polymerase catalytic domain-containing protein 0.0012 0.0044 0.0083
Schistosoma mansoni biogenic amine (5HT) receptor 0.0012 0.0047 0.0041
Plasmodium vivax protein prenyltransferase alpha subunit, putative 0.0022 0.0152 0.2185
Brugia malayi DKFZp564C0469 protein 0.0012 0.0044 0.0038
Loa Loa (eye worm) protein-tyrosine-phosphatase 0.0025 0.0184 0.018
Mycobacterium leprae 3-dehydroquinate synthase AroB 0.0178 0.175 0.3781
Loa Loa (eye worm) hypothetical protein 0.0012 0.0047 0.0041
Giardia lamblia Rab geranylgeranyltransferase 0.0075 0.0696 1
Schistosoma mansoni alpha-1 adrenergic receptor 0.0012 0.0047 0.0041
Loa Loa (eye worm) animal heme peroxidase 0.0064 0.0578 0.058
Mycobacterium ulcerans UDP-N-acetylglucosamine 1-carboxyvinyltransferase 0.0279 0.2791 0.6022
Schistosoma mansoni amine GPCR 0.0012 0.0047 0.0041
Entamoeba histolytica Pten 3-phosphoinositide phosphatase, putative 0.0025 0.0184 0.2077
Echinococcus multilocularis tyrosine protein phosphatase non receptor type 0.0025 0.0184 0.0177
Trypanosoma brucei glycosomal malate dehydrogenase 0.001 0.0023 0.0129
Mycobacterium tuberculosis Probable lipase LipD 0.0043 0.0369 0.1257
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0012 0.0047 0.0041
Brugia malayi hypothetical protein 0.0012 0.0047 0.0041
Loa Loa (eye worm) melatonin receptor type 1A 0.0012 0.0047 0.0041
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.0022 0.0143 0.0139
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0087 0.0816 0.0821
Chlamydia trachomatis DNA ligase 0.0012 0.0044 0.0047
Brugia malayi G-protein coupled receptor 0.0012 0.0047 0.0041
Onchocerca volvulus 0.0025 0.0184 0.2048
Loa Loa (eye worm) hypothetical protein 0.0012 0.0047 0.0041
Loa Loa (eye worm) hypothetical protein 0.0012 0.0047 0.0041
Schistosoma mansoni histamine h1 receptor 0.0012 0.0047 0.0041
Echinococcus granulosus sex peptide receptor 0.0012 0.0047 0.0041
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0043 0.0369 0.0368
Plasmodium falciparum protein farnesyltransferase subunit beta 0.001 0.0029 0.0335
Brugia malayi Protein prenyltransferase alpha subunit repeat containing protein 0.0075 0.0696 0.07
Schistosoma mansoni malate dehydrogenase 0.001 0.0023 0.0016
Echinococcus granulosus tachykinin peptides receptor 99D 0.0012 0.0047 0.0041
Trypanosoma cruzi glycosomal malate dehydrogenase, putative 0.001 0.0023 0.0129
Echinococcus granulosus tyrosine protein phosphatase non receptor type 0.0028 0.0209 0.0205
Trichomonas vaginalis conserved hypothetical protein 0.0012 0.0044 0.0358
Brugia malayi Latrophilin receptor protein 2 0.0018 0.0107 0.0102
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0043 0.0369 0.0368
Brugia malayi hypothetical protein 0.0012 0.0047 0.0041
Loa Loa (eye worm) hypothetical protein 0.0012 0.0047 0.0041
Brugia malayi beta-lactamase family protein 0.0043 0.0369 0.0368
Trypanosoma cruzi importin beta-1 subunit, putative 0.001 0.0028 0.0279
Loa Loa (eye worm) hypothetical protein 0.0024 0.0167 0.0163
Mycobacterium tuberculosis Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) 0.0022 0.0143 0.0437
Trichomonas vaginalis malate dehydrogenase, putative 0.001 0.0023 0.0172
Loa Loa (eye worm) hypothetical protein 0.0025 0.0184 0.018
Brugia malayi G protein-coupled receptor 0.0012 0.0047 0.0041
Brugia malayi Dual specificity protein phosphatase CDC14B 0.0025 0.0184 0.018
Trichomonas vaginalis pten, drome, putative 0.0025 0.0184 0.1562
Loa Loa (eye worm) fibronectin type III domain-containing protein 0.0025 0.0184 0.018
Loa Loa (eye worm) protein-tyrosine phosphatase 0.0025 0.0184 0.018
Echinococcus multilocularis fmrfamide receptor 0.0012 0.0047 0.004
Brugia malayi Protein-tyrosine phosphatase containing protein 0.0025 0.0184 0.018
Onchocerca volvulus 0.0012 0.0047 0.0462
Trichomonas vaginalis ap endonuclease, putative 0.0022 0.0143 0.1211
Loa Loa (eye worm) hypothetical protein 0.0012 0.0047 0.0041
Giardia lamblia Rab geranylgeranyltransferase 0.0022 0.0152 0.211
Plasmodium vivax importin-beta 2, putative 0.0013 0.0053 0.0757
Plasmodium vivax ATP-dependent Clp protease proteolytic subunit, putative 0.0008 0.0006 0.0086
Echinococcus multilocularis G protein coupled 5 hydroxytryptamine receptor 0.0012 0.0047 0.004
Brugia malayi CXXC zinc finger family protein 0.0035 0.0279 0.0276
Mycobacterium ulcerans glutaminase 0.0121 0.1163 0.248
Loa Loa (eye worm) hypothetical protein 0.0012 0.0047 0.0041
Onchocerca volvulus 0.006 0.0536 0.6121
Brugia malayi hypothetical protein 0.0025 0.0184 0.018
Loa Loa (eye worm) hypothetical protein 0.0039 0.0323 0.0321
Echinococcus multilocularis neurogenic locus notch protein 0.0008 0.0007 0.0000000066804
Echinococcus multilocularis tyrosine protein phosphatase non receptor type 0.0028 0.0209 0.0203
Echinococcus multilocularis receptor type tyrosine protein phosphatase 0.0025 0.0184 0.0177
Echinococcus granulosus Polycystic kidney disease protein 0.0024 0.0167 0.0163
Echinococcus granulosus receptor type tyrosine protein phosphatase 0.0025 0.0184 0.018
Trypanosoma cruzi mitochondrial malate dehydrogenase, putative 0.001 0.0023 0.0129
Brugia malayi larval opioid receptor 0.0012 0.0047 0.0041
Brugia malayi neuropeptide F receptor 0.0012 0.0047 0.0041
Onchocerca volvulus 0.0012 0.0047 0.0462
Loa Loa (eye worm) doublecortin family protein 0.0024 0.0167 0.0163
Echinococcus granulosus peroxidasin 0.0064 0.0578 0.058
Mycobacterium leprae PROBABLE ATP-DEPENDENT CLP PROTEASE PROTEOLYTIC SUBUNIT 1 CLPP1 (ENDOPEPTIDASE CLP) 0.0016 0.0082 0.0165
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0018 0.0107 0.0102
Onchocerca volvulus 0.0025 0.0184 0.2048
Leishmania major apurinic/apyrimidinic endonuclease-redox protein 0.0022 0.0143 0.37
Plasmodium falciparum malate dehydrogenase 0.0025 0.0181 0.2539
Onchocerca volvulus 0.0025 0.0184 0.2048
Onchocerca volvulus 0.0092 0.0872 1
Echinococcus multilocularis lipoxygenase domain containing protein 0.0024 0.0167 0.016
Trichomonas vaginalis malate dehydrogenase, putative 0.001 0.0023 0.0172
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative 0.0022 0.0143 0.3561
Echinococcus multilocularis tyrosine protein phosphatase non receptor type 0.0966 0.9863 0.9862
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0012 0.0047 0.004
Loa Loa (eye worm) animal heme peroxidase 0.0064 0.0578 0.058
Schistosoma mansoni peroxidasin 0.0064 0.0578 0.058
Trypanosoma brucei lanosterol synthase 0.0011 0.004 0.061
Schistosoma mansoni amine GPCR 0.0012 0.0047 0.0041
Loa Loa (eye worm) prenyltransferase alpha subunit repeat containing protein 0.0075 0.0696 0.07
Mycobacterium tuberculosis Probable ATP-dependent CLP protease proteolytic subunit 2 ClpP2 (endopeptidase CLP 2) 0.0016 0.0082 0.0215
Schistosoma mansoni neuropeptide f receptor 76f 0.0012 0.0047 0.0041
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.0043 0.0369 0.1257
Echinococcus multilocularis rhodopsin orphan GPCR 0.0012 0.0047 0.004
Loa Loa (eye worm) animal heme peroxidase 0.0064 0.0578 0.058
Brugia malayi notch-like transmembrane receptor 0.0008 0.0007 0.0000000067736
Brugia malayi sulfakinin receptor protein 0.0012 0.0047 0.0041
Leishmania major glycosomal malate dehydrogenase 0.001 0.0023 0.0341
Echinococcus granulosus thyrotropin releasing hormone receptor 0.0012 0.0047 0.0041
Trichomonas vaginalis ran, putative 0.0009 0.0018 0.0133
Schistosoma mansoni hypothetical protein 0.0012 0.0047 0.0041
Brugia malayi Calcitonin receptor-like protein seb-1 0.0057 0.0509 0.0509
Onchocerca volvulus 0.0025 0.0184 0.2048
Loa Loa (eye worm) hypothetical protein 0.0012 0.0047 0.0041
Brugia malayi Protein-tyrosine phosphatase containing protein 0.0025 0.0184 0.018
Trypanosoma brucei cytosolic malate dehydrogenase 0.001 0.0023 0.0129
Trypanosoma cruzi hypothetical protein, conserved 0.0012 0.0044 0.0741
Schistosoma mansoni peroxidasin 0.0064 0.0578 0.058
Trichomonas vaginalis chromosome transmission fidelity factor, putative 0.0012 0.0044 0.0358
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0087 0.0816 0.081
Plasmodium vivax multidomain scavenger receptor, putative 0.0024 0.0167 0.2396
Echinococcus multilocularis g protein coupled receptor 0.0012 0.0047 0.004
Wolbachia endosymbiont of Brugia malayi exonuclease III 0.0022 0.0143 0.036
Loa Loa (eye worm) malate dehydrogenase 0.001 0.0023 0.0016
Loa Loa (eye worm) hypothetical protein 0.0025 0.0184 0.018
Mycobacterium leprae conserved hypothetical protein 0.0043 0.0369 0.0787
Echinococcus multilocularis neuropeptide receptor 0.0012 0.0047 0.004
Loa Loa (eye worm) hypothetical protein 0.0012 0.0047 0.0041
Brugia malayi G protein-coupled receptor F59B2.13 0.0012 0.0047 0.0041
Chlamydia trachomatis ATP-dependent Clp protease proteolytic subunit 0.0024 0.0166 0.0312
Entamoeba histolytica malate dehydrogenase, putative 0.001 0.0023 0.0057
Brugia malayi RE15519p 0.0012 0.0047 0.0041
Echinococcus multilocularis Receptor type tyrosine protein phosphatase O 0.0025 0.0184 0.0177
Echinococcus granulosus rhodopsin orphan GPCR 0.0012 0.0047 0.0041
Echinococcus granulosus lipoxygenase domain containing protein 0.0024 0.0167 0.0163
Echinococcus multilocularis neuropeptide Y receptor 0.0012 0.0047 0.004
Echinococcus granulosus tm gpcr rhodopsin 0.0012 0.0047 0.0041
Schistosoma mansoni lipoxygenase 0.0024 0.0167 0.0163
Schistosoma mansoni rab geranylgeranyl transferase alpha subunit 0.0022 0.0152 0.0148
Onchocerca volvulus 0.0012 0.0047 0.0462
Echinococcus granulosus peptide allatostatin:somatostatin 0.0012 0.0047 0.0041
Echinococcus granulosus rhodopsin orphan GPCR 0.0012 0.0047 0.0041
Leishmania major tyrosine specific protein phosphatase, putative 0.0025 0.0184 0.4834
Brugia malayi Serotonin receptor 0.0012 0.0047 0.0041
Entamoeba histolytica hypothetical protein 0.0087 0.0816 1
Brugia malayi 6-phosphofructokinase 0.0037 0.0306 0.0304
Loa Loa (eye worm) hypothetical protein 0.0013 0.0053 0.0047
Onchocerca volvulus Neuropeptide F receptor homolog 0.0012 0.0047 0.0462
Echinococcus granulosus protein prenyltransferase alpha subunit 0.0022 0.0152 0.0148
Trichomonas vaginalis phosphofructokinase, putative 0.001 0.0026 0.0198
Brugia malayi Dopamine receptor protein 2 0.0012 0.0047 0.0041
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0057 0.0509 0.0509
Entamoeba histolytica hypothetical protein 0.001 0.0028 0.0123
Brugia malayi hypothetical protein 0.0012 0.0047 0.0041
Leishmania major mitochondrial malate dehydrogenase 0.001 0.0023 0.0341
Echinococcus multilocularis RUN 0.0024 0.0167 0.016
Trypanosoma brucei hypothetical protein, conserved 0.0022 0.0152 0.3816
Echinococcus multilocularis lactate dehydrogenase a 0.0025 0.0181 0.0175
Echinococcus granulosus beta LACTamase domain containing family member 0.0043 0.0369 0.0368
Echinococcus granulosus tyrosine protein phosphatase non receptor type 0.0025 0.0184 0.018
Schistosoma mansoni loxhd1 0.0024 0.0167 0.0163
Schistosoma mansoni receptor tyrosine phosphatase type r2a 0.0025 0.0184 0.018
Loa Loa (eye worm) 5-hydroxytryptamine 2C receptor 0.0012 0.0047 0.0041
Loa Loa (eye worm) latrophilin receptor protein 2 0.0018 0.0107 0.0102
Schistosoma mansoni amine GPCR 0.0012 0.0047 0.0041
Echinococcus granulosus dro:myosuppressin receptor 0.0012 0.0047 0.0041
Echinococcus multilocularis mixed lineage leukemia protein mll 0.0009 0.0014 0.0007
Echinococcus multilocularis Receptor type tyrosine protein phosphatase O 0.0025 0.0184 0.0177
Echinococcus granulosus lactate dehydrogenase protein 0.0025 0.0181 0.0177
Mycobacterium tuberculosis Probable ATP-dependent CLP protease proteolytic subunit 1 ClpP1 (endopeptidase CLP) 0.0016 0.0082 0.0215
Loa Loa (eye worm) hypothetical protein 0.0012 0.0047 0.0041
Echinococcus granulosus g protein coupled receptor 0.0012 0.0047 0.0041
Trypanosoma cruzi hypothetical protein, conserved 0.0022 0.0152 0.3816
Echinococcus granulosus rhodopsin orphan GPCR 0.0012 0.0047 0.0041
Echinococcus granulosus somatostatin receptor 0.0012 0.0047 0.0041
Echinococcus multilocularis receptor type tyrosine protein phosphatase H 0.0025 0.0184 0.0177
Schistosoma mansoni myosin xvIII 0.0012 0.0047 0.0041
Brugia malayi hypothetical protein 0.0012 0.0047 0.0041
Echinococcus multilocularis orexin receptor type 2 0.0012 0.0047 0.004
Trypanosoma cruzi BRCA1 C Terminus (BRCT) domain containing protein, putative 0.0012 0.0044 0.0741
Loa Loa (eye worm) hypothetical protein 0.0025 0.0184 0.018
Loa Loa (eye worm) glutaminase 0.0121 0.1163 0.1173
Onchocerca volvulus 0.0012 0.0047 0.0462
Trichomonas vaginalis penicillin-binding protein, putative 0.0043 0.0369 0.3161
Echinococcus granulosus tyrosine protein phosphatase non receptor type 0.0025 0.0184 0.018
Brugia malayi Malate dehydrogenase, cytoplasmic 0.001 0.0023 0.0016
Schistosoma mansoni rgs-gaip interacting protein gipc 0.0025 0.0184 0.018
Echinococcus granulosus tyrosine protein phosphatase non receptor type 0.0028 0.0209 0.0205
Onchocerca volvulus 0.0015 0.0076 0.0805
Brugia malayi Protein-tyrosine phosphatase containing protein 0.0025 0.0184 0.018
Toxoplasma gondii hypothetical protein 0.0022 0.0152 0.0317
Trypanosoma cruzi cytosolic malate dehydrogenase, putative 0.001 0.0023 0.0129
Loa Loa (eye worm) hypothetical protein 0.0012 0.0047 0.0041
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.0043 0.0369 0.1257
Echinococcus multilocularis receptor type tyrosine protein phosphatase F 0.0025 0.0184 0.0177
Echinococcus multilocularis receptor type tyrosine protein phosphatase 0.0025 0.0184 0.0177
Giardia lamblia Endonuclease/Exonuclease/phosphatase 0.0022 0.0143 0.198
Echinococcus granulosus G protein coupled receptor 139 0.0012 0.0047 0.0041
Onchocerca volvulus 0.0012 0.0047 0.0462
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.001 0.0025 0.0019
Trichomonas vaginalis importin beta-1, putative 0.001 0.0028 0.0218
Echinococcus granulosus serotonin receptor 0.0012 0.0047 0.0041
Treponema pallidum exodeoxyribonuclease (exoA) 0.0022 0.0143 0.0493
Brugia malayi hypothetical protein 0.0042 0.0352 0.0351
Onchocerca volvulus 0.0012 0.0047 0.0462
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0012 0.0047 0.0041
Echinococcus multilocularis nibrin 0.0012 0.0044 0.0038
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0012 0.0047 0.0041
Brugia malayi hypothetical protein 0.0012 0.0047 0.0041
Echinococcus granulosus importin subunit beta 1 0.0013 0.0053 0.0047
Plasmodium falciparum AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0022 0.0143 0.1988
Echinococcus granulosus lactate dehydrogenase a 0.0025 0.0181 0.0177
Echinococcus granulosus pyroglutamylated rfamide peptide receptor 0.0012 0.0047 0.0041
Brugia malayi Serotonin receptor 0.0012 0.0047 0.0041
Trichomonas vaginalis Importin beta-1 subunit, putative 0.001 0.0028 0.0218
Loa Loa (eye worm) hypothetical protein 0.001 0.0025 0.0019
Loa Loa (eye worm) hypothetical protein 0.0074 0.0679 0.0683
Trichomonas vaginalis malate dehydrogenase, putative 0.001 0.0023 0.0172
Echinococcus granulosus receptor type tyrosine protein phosphatase 0.0025 0.0184 0.018
Trypanosoma brucei ATP-dependent 6-phosphofructokinase, glycosomal 0.0037 0.0306 0.8207
Echinococcus granulosus protein farnesyltransferase alpha subunit 0.0075 0.0696 0.07
Leishmania major malate dehydrogenase, putative 0.001 0.0023 0.0341
Schistosoma mansoni hypothetical protein 0.0015 0.0076 0.0071
Giardia lamblia Replication factor C, subunit 1 0.0012 0.0044 0.0544
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0011 0.0036 0.0029
Loa Loa (eye worm) protein-tyrosine phosphatase 1 0.0025 0.0184 0.018
Echinococcus multilocularis L lactate dehydrogenase 0.0015 0.008 0.0074
Onchocerca volvulus 0.0025 0.0184 0.2048
Brugia malayi Protein-tyrosine phosphatase containing protein 0.0025 0.0184 0.018
Schistosoma mansoni ran 0.0009 0.0018 0.0012
Onchocerca volvulus 4.1 G protein, putative homolog 0.0025 0.0184 0.2048
Mycobacterium tuberculosis 3-dehydroquinate synthase AroB 0.0178 0.175 0.6265
Loa Loa (eye worm) nucleolar RNA-associated protein alpha 0.0136 0.1319 0.1332
Loa Loa (eye worm) hypothetical protein 0.0012 0.0044 0.0038
Echinococcus multilocularis L lactate dehydrogenase B chain 0.0025 0.0181 0.0175
Mycobacterium ulcerans ATP-dependent Clp protease proteolytic subunit 0.0024 0.0166 0.0312
Onchocerca volvulus 0.0025 0.0184 0.2048
Trichomonas vaginalis protein farnesyltransferase alpha subunit, putative 0.0022 0.0152 0.1289
Schistosoma mansoni growth factor receptor-bound protein 0.0049 0.043 0.043
Echinococcus granulosus rhodopsin orphan GPCR 0.0012 0.0047 0.0041
Onchocerca volvulus 0.0025 0.0184 0.2048
Onchocerca volvulus 0.0024 0.0167 0.1851
Entamoeba histolytica Activator 1 140 kDa subunit, putative 0.0012 0.0044 0.0326
Loa Loa (eye worm) hypothetical protein 0.0025 0.0184 0.018
Brugia malayi latrophilin 2 splice variant baaae 0.0039 0.0323 0.0321
Brugia malayi Animal haem peroxidase family protein 0.0064 0.0578 0.058
Loa Loa (eye worm) hypothetical protein 0.0012 0.0047 0.0041
Echinococcus granulosus neuropeptide receptor 0.0012 0.0047 0.0041
Plasmodium falciparum lactate dehydrogenase, putative 0.001 0.0023 0.0242
Brugia malayi hypothetical protein 0.0025 0.0184 0.018
Echinococcus multilocularis lipoxygenase domain containing protein 0.0024 0.0167 0.016
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0057 0.0509 0.0509
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0012 0.0047 0.0041
Loa Loa (eye worm) dual specificity protein phosphatase CDC14B 0.0025 0.0184 0.018
Loa Loa (eye worm) protein-tyrosine phosphatase 0.0025 0.0184 0.018
Loa Loa (eye worm) hypothetical protein 0.0064 0.0578 0.058
Echinococcus granulosus Receptor type tyrosine protein phosphatase O 0.0025 0.0184 0.018
Leishmania major ATP-dependent phosphofructokinase 0.0037 0.0306 0.8245
Brugia malayi STAT protein, DNA binding domain containing protein 0.0028 0.0214 0.0211
Echinococcus granulosus tyrosine protein phosphatase non receptor type 0.0966 0.9863 1
Loa Loa (eye worm) hypothetical protein 0.0025 0.0184 0.018
Loa Loa (eye worm) protein-tyrosine phosphatase 0.0025 0.0184 0.018
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0074 0.0682 0.0686
Echinococcus granulosus rhodopsin orphan GPCR 0.0012 0.0047 0.0041
Brugia malayi Probable malate dehydrogenase, mitochondrial precursor 0.001 0.0023 0.0016
Toxoplasma gondii ABC1 family protein 0.0043 0.0369 0.0787
Chlamydia trachomatis fructose-6-phosphate phosphotransferase 0.001 0.0026 0.0007
Echinococcus granulosus ATP dependent Clp protease proteolytic subunit 0.0024 0.0166 0.0162
Echinococcus granulosus malate dehydrogenase 0.001 0.0023 0.0016
Trichomonas vaginalis esterase, putative 0.0043 0.0369 0.3161
Brugia malayi Protein-tyrosine phosphatase containing protein 0.0025 0.0184 0.018
Schistosoma mansoni topbp1 0.0012 0.0044 0.0038
Entamoeba histolytica malate dehydrogenase,cytoplasmic, putative 0.001 0.0023 0.0057
Loa Loa (eye worm) hypothetical protein 0.0025 0.0184 0.018
Loa Loa (eye worm) malate dehydrogenase 0.001 0.0023 0.0016
Schistosoma mansoni glutaminase 0.0121 0.1163 0.1173
Brugia malayi hypothetical protein 0.0024 0.0167 0.0163
Trichomonas vaginalis protein farnesyltransferase alpha subunit, putative 0.0075 0.0696 0.598
Echinococcus multilocularis beta LACTamase domain containing family member 0.0043 0.0369 0.0363
Plasmodium falciparum ATP-dependent Clp protease proteolytic subunit 0.0024 0.0166 0.232
Loa Loa (eye worm) hypothetical protein 0.0025 0.0184 0.018
Trypanosoma cruzi hypothetical protein, conserved 0.0043 0.0369 1
Wolbachia endosymbiont of Brugia malayi ATP-dependent Clp protease proteolytic subunit 0.0024 0.0166 0.0444
Echinococcus multilocularis receptor type tyrosine protein phosphatase zeta 0.0025 0.0184 0.0177
Entamoeba histolytica hypothetical protein 0.0087 0.0816 1
Schistosoma mansoni polycystin 1-related 0.0024 0.0167 0.0163
Echinococcus granulosus tumor protein p63 0.0408 0.4121 0.4175
Brugia malayi hypothetical protein 0.0074 0.0679 0.0683
Plasmodium vivax AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0022 0.0143 0.2056
Echinococcus granulosus tm gpcr rhodopsin 0.0012 0.0047 0.0041
Schistosoma mansoni ancient conserved domain protein 2 (cyclin m2) 0.0012 0.0047 0.0041
Brugia malayi Protein-tyrosine phosphatase containing protein 0.0025 0.0184 0.018
Schistosoma mansoni chromosome transmission fidelity factor 0.0012 0.0044 0.0038
Loa Loa (eye worm) STAT protein 0.0028 0.0214 0.0211
Toxoplasma gondii lactate dehydrogenase LDH1 0.0025 0.0181 0.038
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0012 0.0047 0.004
Trypanosoma brucei malate dehydrogenase-related 0.001 0.0023 0.0129
Loa Loa (eye worm) hypothetical protein 0.0012 0.0047 0.0041
Schistosoma mansoni protein farnesyltransferase subunit beta 0.001 0.0029 0.0023
Schistosoma mansoni growth hormone secretagogue receptor 0.0012 0.0047 0.0041
Echinococcus multilocularis malate dehydrogenase 0.001 0.0023 0.0016
Loa Loa (eye worm) hypothetical protein 0.0064 0.0578 0.058
Loa Loa (eye worm) unidentified vitellogenin-linked transcript protein 6 0.0012 0.0047 0.0041
Entamoeba histolytica phosphofructokinase, putative 0.0037 0.0306 0.3611
Loa Loa (eye worm) hypothetical protein 0.0025 0.0184 0.018
Echinococcus granulosus receptor type tyrosine protein phosphatase 0.0025 0.0184 0.018
Schistosoma mansoni cpg binding protein 0.0037 0.0299 0.0297
Onchocerca volvulus 0.0025 0.0184 0.2048
Loa Loa (eye worm) hypothetical protein 0.0012 0.0047 0.0041
Loa Loa (eye worm) hypothetical protein 0.0064 0.0578 0.058
Mycobacterium ulcerans hypothetical protein 0.0043 0.0369 0.0754
Onchocerca volvulus 0.0025 0.0184 0.2048
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0009 0.0014 0.0007
Echinococcus multilocularis GPCR, family 2 0.0018 0.0107 0.0101
Onchocerca volvulus 0.0025 0.0184 0.2048
Schistosoma mansoni muscarinic acetylcholine (GAR) receptor 0.0012 0.0047 0.0041
Onchocerca volvulus 0.0025 0.0184 0.2048
Brugia malayi Pre-SET motif family protein 0.0066 0.0596 0.0598
Loa Loa (eye worm) hypothetical protein 0.0064 0.0578 0.058
Leishmania major hypothetical protein, conserved 0.0043 0.0369 1
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0018 0.0107 0.0102
Onchocerca volvulus 0.0043 0.0369 0.419
Trichomonas vaginalis penicillin-binding protein, putative 0.0043 0.0369 0.3161
Trichomonas vaginalis geranylgeranyl transferase type I beta subunit, putative 0.001 0.0029 0.0228
Echinococcus granulosus protein tyrosine phosphatase n9 0.0025 0.0184 0.018
Echinococcus multilocularis rhodopsin orphan GPCR 0.0012 0.0047 0.004
Brugia malayi Blistered cuticle protein 3 0.0064 0.0578 0.058
Echinococcus multilocularis neuropeptides capa receptor 0.0012 0.0047 0.004
Echinococcus multilocularis rhodopsin orphan GPCR 0.0012 0.0047 0.004
Onchocerca volvulus 0.0012 0.0047 0.0462
Brugia malayi phosphofructokinase 0.0037 0.0306 0.0304
Onchocerca volvulus 0.0025 0.0184 0.2048
Trichomonas vaginalis glutaminase, putative 0.0121 0.1163 1
Entamoeba histolytica pyrophosphate-dependent phosphofructokinase 0.001 0.0026 0.0095
Mycobacterium tuberculosis Conserved protein 0.0043 0.0369 0.1257
Echinococcus granulosus tm gpcr rhodopsin 0.0012 0.0047 0.0041
Echinococcus multilocularis tyrosine protein phosphatase non receptor type 0.0025 0.0184 0.0177
Plasmodium falciparum L-lactate dehydrogenase 0.0025 0.0181 0.2539
Echinococcus multilocularis receptor type tyrosine protein phosphatase zeta 0.0025 0.0184 0.0177
Loa Loa (eye worm) hypothetical protein 0.0025 0.0184 0.018
Schistosoma mansoni amine GPCR 0.0012 0.0047 0.0041
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.0015 0.0076 0.0071
Trichomonas vaginalis D-aminoacylase, putative 0.0043 0.0369 0.3161
Echinococcus multilocularis rhodopsin orphan GPCR 0.0012 0.0047 0.004
Schistosoma mansoni peptide (allatostatin)-like receptor 0.0012 0.0047 0.0041
Plasmodium falciparum importin beta, putative 0.0013 0.0053 0.0677
Loa Loa (eye worm) phosphofructokinase 0.0037 0.0306 0.0304
Onchocerca volvulus 0.0064 0.0578 0.6603
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.0022 0.0143 0.0137
Mycobacterium leprae probable 3-phosphoshikimate 1-carboxyvinyl transferase AroA (5-ENOLPYRUVYLSHIKIMATE-3-PHOSPHATE SYNTHASE) (EPSP SYNTHASE) (EPSPS 0.0456 0.462 1
Loa Loa (eye worm) hypothetical protein 0.0025 0.0184 0.018
Loa Loa (eye worm) hypothetical protein 0.0012 0.0047 0.0041
Mycobacterium tuberculosis Conserved protein 0.0043 0.0369 0.1257
Brugia malayi Protein-tyrosine phosphatase containing protein 0.0025 0.0184 0.018
Echinococcus multilocularis receptor type tyrosine protein phosphatase protein tyrosine phosphatase receptor type 0.0025 0.0184 0.0177
Echinococcus granulosus receptor type tyrosine protein phosphatase 0.0025 0.0184 0.018
Loa Loa (eye worm) hypothetical protein 0.0064 0.0578 0.058
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0018 0.0107 0.0101
Echinococcus multilocularis G-protein coupled receptor, putative 0.0012 0.0047 0.004
Brugia malayi Sex muscle abnormal protein 5 0.0049 0.043 0.043
Trypanosoma cruzi tyrosine specific protein phosphatase, putative 0.0025 0.0184 0.4721
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0066 0.0596 0.0598
Onchocerca volvulus 0.0025 0.0184 0.2048
Brugia malayi hypothetical protein 0.0012 0.0047 0.0041
Brugia malayi Animal haem peroxidase family protein 0.0064 0.0578 0.058
Echinococcus granulosus GPCR family 2 0.0018 0.0107 0.0102
Echinococcus multilocularis ATP dependent Clp protease proteolytic subunit 0.0024 0.0166 0.016
Brugia malayi exodeoxyribonuclease III family protein 0.0022 0.0143 0.0139
Loa Loa (eye worm) hypothetical protein 0.0008 0.0007 0.0000000067736
Echinococcus multilocularis Receptor type tyrosine protein phosphatase O 0.0025 0.0184 0.0177
Schistosoma mansoni pcd6 interacting protein-related 0.0025 0.0184 0.018
Echinococcus multilocularis lactate dehydrogenase a 0.0025 0.0181 0.0175
Brugia malayi 6-phosphofructokinase 0.0037 0.0306 0.0304
Echinococcus granulosus 7TM GPCR rhodopsin 0.0012 0.0047 0.0041
Onchocerca volvulus 0.0012 0.0047 0.0462
Echinococcus multilocularis cpg binding protein 0.0037 0.0299 0.0293
Echinococcus multilocularis g-protein coupled receptor 0.0012 0.0047 0.004
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0043 0.0369 0.0368
Echinococcus granulosus lactate dehydrogenase a 0.0025 0.0181 0.0177
Toxoplasma gondii EGF family domain-containing protein 0.0008 0.0007 0.0001
Brugia malayi beta-lactamase 0.0043 0.0369 0.0368
Trichomonas vaginalis protein farnesyltransferase alpha subunit, putative 0.0075 0.0696 0.598
Loa Loa (eye worm) hypothetical protein 0.0025 0.0184 0.018
Chlamydia trachomatis UDP-N-acetylglucosamine 1-carboxyvinyltransferase 0.0279 0.2791 0.6022
Loa Loa (eye worm) animal heme peroxidase 0.0064 0.0578 0.058
Schistosoma mansoni opsin-like receptor 0.0012 0.0047 0.0041
Loa Loa (eye worm) hypothetical protein 0.0025 0.0184 0.018
Toxoplasma gondii ATP-dependent Clp endopeptidase, proteolytic subunit ClpP domain-containing protein 0.0024 0.0166 0.0347
Onchocerca volvulus 0.0025 0.0184 0.2048
Onchocerca volvulus Neurogenic locus notch protein homolog 0.0008 0.0007 0.000000077128
Entamoeba histolytica protein tyrosine phosphatase, putative 0.0025 0.0184 0.2077
Trichomonas vaginalis malate dehydrogenase, putative 0.001 0.0023 0.0172
Schistosoma mansoni ap endonuclease 0.0022 0.0143 0.0139
Mycobacterium ulcerans exodeoxyribonuclease III protein XthA 0.0022 0.0143 0.0262
Trypanosoma cruzi hypothetical protein, conserved 0.0043 0.0369 1
Schistosoma mansoni 3-dehydroquinate synthase 0.0178 0.175 0.1769
Loa Loa (eye worm) G-protein coupled receptor 0.0012 0.0047 0.0041
Echinococcus multilocularis tumor protein p63 0.0408 0.4121 0.4117
Echinococcus granulosus allatostatin A receptor 0.0012 0.0047 0.0041
Echinococcus granulosus L lactate dehydrogenase 0.0015 0.008 0.0075
Schistosoma mansoni histamine-responsive GPCR (AAF21638) 0.0012 0.0047 0.0041
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0009 0.0014 0.0007
Echinococcus multilocularis peroxidasin 0.0064 0.0578 0.0572
Trichomonas vaginalis 6-phosphofructokinase, putative 0.001 0.0026 0.0198
Schistosoma mansoni topbp1 0.0012 0.0044 0.0038
Echinococcus granulosus neuropeptide Y receptor 0.0012 0.0047 0.0041
Trypanosoma brucei protein farnesyltransferase beta subunit 0.001 0.0029 0.0313
Brugia malayi F/Y-rich N-terminus family protein 0.0011 0.0034 0.0028
Trichomonas vaginalis malate dehydrogenase, putative 0.001 0.0023 0.0172
Mycobacterium tuberculosis Possible penicillin-binding protein 0.0278 0.2781 1
Trichomonas vaginalis ap endonuclease, putative 0.0022 0.0143 0.1211
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0012 0.0047 0.0041
Loa Loa (eye worm) hypothetical protein 0.0043 0.0369 0.0368
Brugia malayi hypothetical protein 0.0012 0.0047 0.0041
Trichomonas vaginalis malate dehydrogenase, putative 0.001 0.0023 0.0172
Brugia malayi Protein-tyrosine phosphatase containing protein 0.0025 0.0184 0.018
Trichomonas vaginalis chromosome transmission fidelity factor, putative 0.0012 0.0044 0.0358
Loa Loa (eye worm) hypothetical protein 0.0012 0.0044 0.0038
Toxoplasma gondii HEAT repeat-containing protein 0.0013 0.0053 0.0101
Echinococcus multilocularis alpha 1A adrenergic receptor 0.0012 0.0047 0.004
Echinococcus granulosus replication factor c subunit 1 0.0012 0.0044 0.0038
Echinococcus granulosus survival motor neuron protein 1 0.0074 0.0679 0.0683
Plasmodium vivax SET domain protein, putative 0.001 0.0025 0.0362
Loa Loa (eye worm) hypothetical protein 0.0012 0.0047 0.0041
Echinococcus granulosus biogenic amine 5HT receptor 0.0012 0.0047 0.0041
Echinococcus granulosus cpg binding protein 0.0037 0.0299 0.0297
Trypanosoma brucei BRCA1 C Terminus (BRCT) domain containing protein, putative 0.0012 0.0044 0.0741
Loa Loa (eye worm) protein-tyrosine phosphatase 0.0025 0.0184 0.018
Plasmodium vivax hypothetical protein, conserved 0.0043 0.0369 0.5304
Loa Loa (eye worm) hypothetical protein 0.0012 0.0047 0.0041
Mycobacterium leprae PROBABLE ATP-DEPENDENT CLP PROTEASE PROTEOLYTIC SUBUNIT 2 CLPP2 (ENDOPEPTIDASE CLP 2) 0.0024 0.0166 0.0347
Loa Loa (eye worm) hypothetical protein 0.0012 0.0047 0.0041
Trypanosoma brucei importin beta-1 subunit, putative 0.0013 0.0053 0.0984
Echinococcus granulosus peptidase Clp S14 family 0.0016 0.0082 0.0076
Schistosoma mansoni malate dehydrogenase 0.001 0.0023 0.0016
Trypanosoma cruzi malate dehydrogenase, putative 0.001 0.0023 0.0129
Brugia malayi GnHR receptor homolog 0.0012 0.0047 0.0041
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0018 0.0107 0.0101
Echinococcus multilocularis neuropeptide receptor 0.0012 0.0047 0.004
Onchocerca volvulus 0.0024 0.0167 0.1851
Loa Loa (eye worm) hypothetical protein 0.0012 0.0047 0.0041
Echinococcus multilocularis lactate dehydrogenase a 0.0025 0.0181 0.0175
Onchocerca volvulus 0.0064 0.0578 0.6603
Echinococcus multilocularis rhodopsin orphan GPCR 0.0012 0.0047 0.004
Loa Loa (eye worm) protein-tyrosine phosphatase 0.0028 0.0209 0.0205
Schistosoma mansoni growth factor receptor-bound protein 0.0049 0.043 0.043
Giardia lamblia Protein tyrosine phosphatase 0.0025 0.0184 0.2571
Toxoplasma gondii shikimate dehydrogenase substrate binding domain-containing protein 0.0456 0.462 1
Schistosoma mansoni hypothetical protein 0.0087 0.0816 0.0821
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.001 0.0025 0.0019
Loa Loa (eye worm) hypothetical protein 0.0012 0.0047 0.0041
Trypanosoma cruzi hypothetical protein, conserved 0.0022 0.0152 0.3816
Toxoplasma gondii lactate dehydrogenase LDH2 0.0025 0.0181 0.038
Schistosoma mansoni biogenic amine receptor 0.0012 0.0047 0.0041
Echinococcus multilocularis receptor type tyrosine protein phosphatase 0.0025 0.0184 0.0177
Mycobacterium tuberculosis 3-phosphoshikimate 1-carboxyvinyltransferase AroA (5-enolpyruvylshikimate-3-phosphate synthase) (EPSP synthase) (EPSPS) 0.0178 0.175 0.6265
Trypanosoma brucei mitochondrial malate dehydrogenase 0.001 0.0023 0.0129
Echinococcus multilocularis allatostatin A receptor 0.0012 0.0047 0.004
Loa Loa (eye worm) hypothetical protein 0.0012 0.0047 0.0041
Echinococcus multilocularis growth factor receptor bound protein 2 0.0049 0.043 0.0424
Entamoeba histolytica exodeoxyribonuclease III, putative 0.0022 0.0143 0.1567
Loa Loa (eye worm) glutaminase 2 0.0121 0.1163 0.1173
Loa Loa (eye worm) gonadotropin-releasing hormone receptor 2 0.0012 0.0047 0.0041
Trichomonas vaginalis phosphofructokinase, putative 0.001 0.0026 0.0198
Plasmodium falciparum ATP-dependent 6-phosphofructokinase 0.001 0.0026 0.0285
Echinococcus granulosus neuropeptides capa receptor 0.0012 0.0047 0.0041
Echinococcus granulosus nuclear factor of activated T cells 5 0.0023 0.0158 0.0153
Plasmodium falciparum LCCL domain-containing protein 0.0024 0.0167 0.233
Schistosoma mansoni receptor tyrosine phosphatase type r2a 0.0025 0.0184 0.018
Loa Loa (eye worm) protein-tyrosine phosphatase 0.0025 0.0184 0.018
Echinococcus multilocularis neuropeptides capa receptor 0.0012 0.0047 0.004
Trypanosoma cruzi ATP-dependent 6-phosphofructokinase, glycosomal 0.0037 0.0306 0.8207
Leishmania major malate dehydrogenase, putative 0.0025 0.0181 0.476
Brugia malayi Pax transcription activation domain interacting protein 0.0012 0.0044 0.0038
Loa Loa (eye worm) hypothetical protein 0.0075 0.0696 0.07
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0012 0.0047 0.0041
Loa Loa (eye worm) neuropeptide F receptor 0.0012 0.0047 0.0041
Loa Loa (eye worm) protein-tyrosine phosphatase 0.0092 0.0872 0.0878
Schistosoma mansoni protein tyrosine phosphatase 0.0025 0.0184 0.018
Brugia malayi Animal haem peroxidase family protein 0.0064 0.0578 0.058
Loa Loa (eye worm) hypothetical protein 0.0057 0.0509 0.0509
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.001 0.0025 0.0019
Mycobacterium ulcerans 6-phosphofructokinase 0.0037 0.0306 0.0617
Brugia malayi Pre-SET motif family protein 0.001 0.0025 0.0019
Loa Loa (eye worm) hypothetical protein 0.0025 0.0184 0.018
Onchocerca volvulus 0.0012 0.0047 0.0462
Echinococcus multilocularis fmrfamide receptor 0.0012 0.0047 0.004
Loa Loa (eye worm) hypothetical protein 0.0012 0.0047 0.0041
Brugia malayi putative neuropeptide receptor NPR1 0.0012 0.0047 0.0041
Trichomonas vaginalis type I geranylgeranyltransferase beta subunit, putative 0.001 0.0029 0.0228
Schistosoma mansoni opsin-like receptor 0.0012 0.0047 0.0041
Loa Loa (eye worm) protein-tyrosine phosphatase 0.0025 0.0184 0.018
Loa Loa (eye worm) hypothetical protein 0.0012 0.0047 0.0041
Echinococcus multilocularis hypothetical protein 0.0025 0.0184 0.0177
Brugia malayi Protein-tyrosine phosphatase containing protein 0.0025 0.0184 0.018
Schistosoma mansoni protein tyrosine phosphatase non-receptor type nt1 0.0966 0.9863 1
Chlamydia trachomatis ATP-dependent Clp protease proteolytic subunit 0.0024 0.0166 0.0312
Schistosoma mansoni survival motor neuron protein 0.0015 0.0076 0.0071
Echinococcus multilocularis neuropeptide s receptor 0.0012 0.0047 0.004
Onchocerca volvulus Peroxidasin homolog 0.0064 0.0578 0.6603
Trichomonas vaginalis RNA polymerase II ctd phosphatase, putative 0.0012 0.0044 0.0358
Echinococcus granulosus G protein coupled 5 hydroxytryptamine receptor 0.0012 0.0047 0.0041
Schistosoma mansoni lipoxygenase 0.0067 0.0608 0.061
Echinococcus granulosus orexin receptor type 2 0.0012 0.0047 0.0041
Schistosoma mansoni biogenic amine (octopamine/dopamine) receptor 0.0012 0.0047 0.0041
Schistosoma mansoni protein tyrosine phosphatase n11 (shp2) 0.0028 0.0209 0.0205
Echinococcus granulosus cytosolic malate dehydrogenase 0.001 0.0023 0.0016
Entamoeba histolytica protein tyrosine phosphatase, putative 0.0025 0.0184 0.2077
Trichomonas vaginalis malate and lactate dehydrogenase, putative 0.001 0.0023 0.0172
Echinococcus multilocularis neuropeptide receptor A26 0.0012 0.0047 0.004
Loa Loa (eye worm) prenyltransferase and squalene oxidase repeat family protein 0.001 0.0029 0.0023
Echinococcus granulosus growth factor receptor bound protein 2 0.0049 0.043 0.043
Schistosoma mansoni protein tyrosine phosphatase 0.0025 0.0184 0.018
Loa Loa (eye worm) blistered cuticle protein 3 0.0064 0.0578 0.058
Brugia malayi Probable ClpP-like protease 0.0024 0.0166 0.0162
Brugia malayi Protein-tyrosine phosphatase containing protein 0.0025 0.0184 0.018
Loa Loa (eye worm) CXXC zinc finger family protein 0.0035 0.0279 0.0276
Echinococcus multilocularis rhodopsin orphan GPCR 0.0012 0.0047 0.004
Schistosoma mansoni DNA ligase IV 0.0012 0.0044 0.0038
Echinococcus multilocularis lactate dehydrogenase protein 0.0025 0.0181 0.0175
Echinococcus multilocularis receptor type tyrosine protein phosphatase 0.0025 0.0184 0.0177
Echinococcus multilocularis pyroglutamylated rfamide peptide receptor 0.0012 0.0047 0.004
Loa Loa (eye worm) hypothetical protein 0.0025 0.0184 0.018
Echinococcus multilocularis somatostatin receptor 0.0012 0.0047 0.004
Loa Loa (eye worm) hypothetical protein 0.0012 0.0047 0.0041
Entamoeba histolytica protein farnesyltransferase alpha subunit, putative 0.0075 0.0696 0.8498
Brugia malayi hypothetical protein 0.0012 0.0044 0.0038
Trichomonas vaginalis phosphofructokinase, putative 0.0037 0.0306 0.2618
Trichomonas vaginalis phosphofructokinase, putative 0.001 0.0026 0.0198
Onchocerca volvulus 0.0025 0.0184 0.2048
Loa Loa (eye worm) 6-phosphofructokinase 0.0037 0.0306 0.0304
Loa Loa (eye worm) hypothetical protein 0.0018 0.0107 0.0102
Trichomonas vaginalis set domain proteins, putative 0.0074 0.0688 0.5912
Schistosoma mansoni hypothetical protein 0.0136 0.1319 0.1332
Loa Loa (eye worm) hypothetical protein 0.0064 0.0578 0.058
Trichomonas vaginalis geranylgeranyl transferase type II beta subunit, putative 0.001 0.0029 0.0228
Loa Loa (eye worm) protein tyrosine phosphatase 0.0025 0.0184 0.018
Loa Loa (eye worm) G-protein coupled receptor 0.0012 0.0047 0.0041
Loa Loa (eye worm) protein-tyrosine phosphatase 0.0025 0.0184 0.018
Loa Loa (eye worm) prenyltransferase alpha subunit repeat containing protein 0.0022 0.0152 0.0148
Echinococcus multilocularis Polycystic kidney disease protein 0.0024 0.0167 0.016
Schistosoma mansoni neuropeptide receptor 0.0012 0.0047 0.0041
Brugia malayi Protein-tyrosine phosphatase containing protein 0.0966 0.9863 1
Brugia malayi Protein-tyrosine phosphatase containing protein 0.0025 0.0184 0.018
Loa Loa (eye worm) hypothetical protein 0.0064 0.0578 0.058
Entamoeba histolytica Rab geranylgeranyltransferase alpha subunit, putative 0.0022 0.0152 0.1679
Loa Loa (eye worm) hypothetical protein 0.0012 0.0047 0.0041
Echinococcus granulosus neuropeptide receptor A26 0.0012 0.0047 0.0041
Schistosoma mansoni importin beta-1 0.0013 0.0053 0.0047
Brugia malayi Protein-tyrosine phosphatase containing protein 0.0025 0.0184 0.018
Wolbachia endosymbiont of Brugia malayi UDP-N-acetylglucosamine 1-carboxyvinyltransferase 0.0279 0.2791 1
Leishmania major malate dehydrogenase 0.001 0.0023 0.0341
Brugia malayi ATP dependent DNA ligase C terminal region family protein 0.0012 0.0044 0.0038
Echinococcus multilocularis neuropeptide FF receptor 2 0.0012 0.0047 0.004
Loa Loa (eye worm) hypothetical protein 0.0025 0.0184 0.018
Echinococcus multilocularis protein farnesyltransferase subunit beta 0.001 0.0029 0.0022
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0012 0.0047 0.004
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0011 0.0036 0.003
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.0022 0.0143 0.3561
Schistosoma mansoni rab6-interacting 0.0024 0.0167 0.0163
Trichomonas vaginalis geranylgeranyl transferase type beta subunit, putative 0.001 0.0029 0.0228
Schistosoma mansoni amine GPCR 0.0012 0.0047 0.0041
Echinococcus granulosus lipoxygenase domain containing protein 0.0024 0.0167 0.0163
Echinococcus granulosus rhodopsin orphan GPCR 0.0012 0.0047 0.0041
Brugia malayi follicle stimulating hormone receptor 0.0012 0.0047 0.0041
Brugia malayi Doublecortin family protein 0.0024 0.0167 0.0163
Loa Loa (eye worm) histone methyltransferase 0.0011 0.0036 0.003
Mycobacterium ulcerans ATP-dependent Clp protease proteolytic subunit 0.0024 0.0166 0.0312
Schistosoma mansoni protein tyrosine phosphatase 0.0025 0.0184 0.018
Echinococcus granulosus receptor type tyrosine protein phosphatase 0.0025 0.0184 0.018
Loa Loa (eye worm) hypothetical protein 0.0012 0.0044 0.0038
Giardia lamblia Pyrophosphate-fructose 6-phosphate 1-phosphotransferase alpha subunit 0.001 0.0026 0.0276
Brugia malayi Melatonin receptor type 1A 0.0012 0.0047 0.0041
Loa Loa (eye worm) hypothetical protein 0.0025 0.0184 0.018
Echinococcus multilocularis rhodopsin orphan GPCR 0.0012 0.0047 0.004
Schistosoma mansoni hypothetical protein 0.0012 0.0047 0.0041
Plasmodium vivax prenyltransferase alpha subunit, putative 0.0075 0.0696 1
Schistosoma mansoni 6-phosphofructokinase 0.0037 0.0306 0.0304
Schistosoma mansoni neuropeptide receptor 0.0012 0.0047 0.0041
Echinococcus multilocularis nuclear factor of activated T cells 5 0.0023 0.0158 0.0151
Trichomonas vaginalis malate and lactate dehydrogenase, putative 0.001 0.0023 0.0172
Trichomonas vaginalis phosphofructokinase, putative 0.001 0.0026 0.0198
Echinococcus granulosus RUN 0.0024 0.0167 0.0163
Trypanosoma cruzi protein farnesyltransferase, putative 0.001 0.0029 0.0313
Onchocerca volvulus 0.0092 0.0872 1
Loa Loa (eye worm) protein-tyrosine phosphatase 0.0025 0.0184 0.018
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0043 0.0369 0.0368
Plasmodium vivax 6-phosphofructokinase, putative 0.001 0.0026 0.0369
Echinococcus multilocularis serotonin receptor 0.0012 0.0047 0.004
Schistosoma mansoni L-lactate dehydrogenase 0.001 0.0023 0.0016
Brugia malayi GTP-binding nuclear protein RAN/TC4 0.0009 0.0018 0.0012
Loa Loa (eye worm) GTP-binding nuclear protein RAN/TC4 0.0009 0.0018 0.0012
Onchocerca volvulus Peroxidase homolog 0.0064 0.0578 0.6603
Onchocerca volvulus 0.0012 0.0047 0.0462
Schistosoma mansoni protein farnesyltransferase alpha subunit 0.0075 0.0696 0.07
Loa Loa (eye worm) hypothetical protein 0.0012 0.0047 0.0041
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.0043 0.0369 0.0754
Loa Loa (eye worm) hypothetical protein 0.0012 0.0047 0.0041
Brugia malayi Protein-tyrosine phosphatase containing protein 0.0025 0.0184 0.018
Schistosoma mansoni protein-tyrosine phosphatase non-receptor type nt5 0.0025 0.0184 0.018
Schistosoma mansoni adenoreceptor 0.0012 0.0047 0.0041
Echinococcus granulosus neuropeptide FF receptor 2 0.0012 0.0047 0.0041
Onchocerca volvulus 0.0012 0.0047 0.0462
Mycobacterium tuberculosis Probable conserved lipoprotein 0.0043 0.0369 0.1257
Schistosoma mansoni cpg binding protein 0.0035 0.0279 0.0276
Giardia lamblia Malate dehydrogenase 0.001 0.0023 0.0232
Echinococcus granulosus receptor type tyrosine protein phosphatase zeta 0.0025 0.0184 0.018
Loa Loa (eye worm) hypothetical protein 0.0043 0.0369 0.0368
Echinococcus granulosus growth hormone secretagogue receptor type 1 0.0012 0.0047 0.0041
Onchocerca volvulus 0.0012 0.0047 0.0462
Brugia malayi hypothetical protein 0.0025 0.0184 0.018
Echinococcus granulosus fmrfamide receptor 0.0012 0.0047 0.0041
Chlamydia trachomatis fructose-6-phosphate phosphotransferase 0.001 0.0026 0.0007
Trichomonas vaginalis geranylgeranyl transferase type II beta subunit, putative 0.001 0.0029 0.0228
Trypanosoma cruzi tyrosine specific protein phosphatase, putative 0.0025 0.0184 0.4721
Brugia malayi hypothetical protein 0.0012 0.0047 0.0041
Trichomonas vaginalis phosphofructokinase, putative 0.001 0.0026 0.0198
Loa Loa (eye worm) hypothetical protein 0.0012 0.0047 0.0041
Brugia malayi hypothetical protein 0.0012 0.0047 0.0041
Loa Loa (eye worm) hypothetical protein 0.0043 0.0369 0.0368
Schistosoma mansoni protein-tyrosine phosphatase n9 0.0025 0.0184 0.018
Loa Loa (eye worm) hypothetical protein 0.0043 0.0369 0.0368
Brugia malayi RNA, U transporter 1 0.0036 0.0294 0.0292
Brugia malayi Importin beta-1 subunit 0.0013 0.0053 0.0047
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0012 0.0047 0.004
Loa Loa (eye worm) hypothetical protein 0.0109 0.1044 0.1053
Echinococcus granulosus biogenic amine 5HT receptor 0.0012 0.0047 0.0041
Loa Loa (eye worm) hypothetical protein 0.0064 0.0578 0.058
Loa Loa (eye worm) hypothetical protein 0.0025 0.0184 0.018
Echinococcus multilocularis cytosolic malate dehydrogenase 0.001 0.0023 0.0016
Trypanosoma brucei protein farnesyltransferase alpha subunit, putative 0.0022 0.0152 0.3816
Loa Loa (eye worm) protein-tyrosine phosphatase 0.0025 0.0184 0.018
Trichomonas vaginalis protein farnesyltransferase alpha subunit/RAB geranylgeranyl transferase alpha subunit, putative 0.0075 0.0696 0.598
Loa Loa (eye worm) hypothetical protein 0.0043 0.0369 0.0368
Trypanosoma cruzi tyrosine specific protein phosphatase, putative 0.0025 0.0184 0.4721
Loa Loa (eye worm) hypothetical protein 0.0064 0.0578 0.058
Echinococcus multilocularis cytosolic malate dehydrogenase 0.001 0.0023 0.0016
Loa Loa (eye worm) hypothetical protein 0.0064 0.0578 0.058
Chlamydia trachomatis dehyroquinate synthase 0.0178 0.175 0.3759
Entamoeba histolytica protein farnesyltransferase beta subunit, putative 0.001 0.0029 0.0138
Schistosoma mansoni biogenic amine receptor 0.0012 0.0047 0.0041
Echinococcus granulosus tyrosine protein phosphatase non receptor type 0.0025 0.0184 0.018
Echinococcus granulosus histone lysine methyltransferase setb 0.001 0.0025 0.0019
Schistosoma mansoni receptor protein tyrosine phosphatase 0.0025 0.0184 0.018
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0012 0.0047 0.0041
Echinococcus multilocularis arachidonate 5 lipoxygenase 0.0067 0.0608 0.0602
Loa Loa (eye worm) hypothetical protein 0.0025 0.0184 0.018
Trichomonas vaginalis malate and lactate dehydrogenase, putative 0.001 0.0023 0.0172
Echinococcus granulosus neuropeptides capa receptor 0.0012 0.0047 0.0041
Schistosoma mansoni malate dehydrogenase 0.001 0.0023 0.0016
Trypanosoma cruzi glycosomal malate dehydrogenase, putative 0.001 0.0023 0.0129
Brugia malayi Serotonin/octopamine receptor family protein 7 0.0012 0.0047 0.0041
Plasmodium vivax ATP-dependent Clp protease proteolytic subunit, putative 0.0024 0.0166 0.2386
Plasmodium falciparum replication factor C subunit 1, putative 0.0012 0.0044 0.0553
Echinococcus multilocularis geranylgeranyl transferase type 2 subunit alpha 0.0022 0.0152 0.0146
Loa Loa (eye worm) hypothetical protein 0.0012 0.0047 0.0041
Schistosoma mansoni ran 0.0009 0.0018 0.0012
Trypanosoma cruzi FHA domain containing protein, putative 0.0012 0.0044 0.0741
Onchocerca volvulus 0.0022 0.0152 0.1681
Echinococcus granulosus GTP binding nuclear protein Ran 0.0009 0.0018 0.0012
Plasmodium falciparum ATP-dependent 6-phosphofructokinase 0.001 0.0026 0.0285
Mycobacterium tuberculosis Conserved protein 0.0043 0.0369 0.1257
Schistosoma mansoni peptide (allatostatin/somatostatin)-like receptor 0.0012 0.0047 0.0041
Brugia malayi hypothetical protein 0.0025 0.0184 0.018
Echinococcus granulosus neuropeptide Y receptor 0.0012 0.0047 0.0041
Treponema pallidum diphosphate--fructose-6-phosphate 1-phosphotransferase 0.001 0.0026 0.0071
Schistosoma mansoni hypothetical protein 0.0018 0.0107 0.0102
Loa Loa (eye worm) TYRA-2 protein 0.0012 0.0047 0.0041
Plasmodium vivax lactate dehydrogenase 0.0025 0.0181 0.2603
Loa Loa (eye worm) hypothetical protein 0.0025 0.0184 0.018
Loa Loa (eye worm) hypothetical protein 0.0012 0.0047 0.0041
Trichomonas vaginalis Importin beta-1 subunit, putative 0.001 0.0028 0.0218
Schistosoma mansoni receptor protein tyrosine phosphatase n (ia2) 0.0025 0.0184 0.018
Schistosoma mansoni transcription factor LCR-F1 0.0087 0.0816 0.0821
Loa Loa (eye worm) hypothetical protein 0.0025 0.0184 0.018
Brugia malayi lactate dehydrogenase. 0.0025 0.0181 0.0177
Brugia malayi hypothetical protein 0.0012 0.0044 0.0038
Loa Loa (eye worm) hypothetical protein 0.0012 0.0047 0.0041
Trypanosoma brucei protein tyrosine phosphatase 1 0.0025 0.0184 0.4721
Echinococcus multilocularis rhodopsin orphan GPCR 0.0012 0.0047 0.004
Onchocerca volvulus 0.0025 0.0184 0.2048
Brugia malayi neuropeptide F receptor 0.0012 0.0047 0.0041
Brugia malayi putative neuropeptide receptor 0.0012 0.0047 0.0041
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.001 0.0025 0.0042
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0012 0.0047 0.004
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0012 0.0047 0.0041
Schistosoma mansoni hypothetical protein 0.0012 0.0047 0.0041
Plasmodium falciparum GTP-binding nuclear protein RAN/TC4 0.0009 0.0018 0.0176
Trypanosoma brucei hypothetical protein, conserved 0.0043 0.0369 1
Loa Loa (eye worm) hypothetical protein 0.0025 0.0184 0.018
Echinococcus multilocularis survival motor neuron protein 1 0.0074 0.0679 0.0673
Trypanosoma cruzi malate dehydrogenase, putative 0.001 0.0023 0.0129
Onchocerca volvulus Dopamine\/Ecdysteroid receptor homolog 0.0012 0.0047 0.0462
Echinococcus granulosus receptor type tyrosine protein phosphatase 0.0025 0.0184 0.018
Trypanosoma cruzi apurinic/apyrimidinic endonuclease 0.0022 0.0143 0.3561
Schistosoma mansoni thyrotropin-releasing hormone receptor 0.0012 0.0047 0.0041
Loa Loa (eye worm) hypothetical protein 0.0012 0.0047 0.0041
Mycobacterium leprae PROBABLE 6-PHOSPHOFRUCTOKINASE PFKA (PHOSPHOHEXOKINASE) (PHOSPHOFRUCTOKINASE) 0.0037 0.0306 0.0651
Echinococcus multilocularis g protein coupled receptor 0.0012 0.0047 0.004
Mycobacterium tuberculosis Probable 6-phosphofructokinase PfkA (phosphohexokinase) (phosphofructokinase) 0.0037 0.0306 0.1028
Leishmania major protein-tyrosine phosphatase 1-like protein 0.0025 0.0184 0.4834
Trichomonas vaginalis malate dehydrogenase, putative 0.001 0.0023 0.0172
Mycobacterium ulcerans 3-phosphoshikimate 1-carboxyvinyltransferase 0.0456 0.462 1
Treponema pallidum UDP-N-acetylglucosamine 1-carboxyvinyltransferase 0.0279 0.2791 1
Onchocerca volvulus 0.0064 0.0578 0.6603
Onchocerca volvulus 0.0025 0.0184 0.2048
Schistosoma mansoni biogenic amine receptor 0.0012 0.0047 0.0041
Onchocerca volvulus Dual oxidase homolog 0.0064 0.0578 0.6603
Trichomonas vaginalis phosphofructokinase, putative 0.001 0.0026 0.0198
Loa Loa (eye worm) hypothetical protein 0.0025 0.0184 0.018
Mycobacterium tuberculosis Probable lipase LipE 0.0043 0.0369 0.1257
Loa Loa (eye worm) protein-tyrosine phosphatase 0.0025 0.0184 0.018
Echinococcus multilocularis G protein coupled receptor 139 0.0012 0.0047 0.004
Loa Loa (eye worm) hypothetical protein 0.0012 0.0044 0.0038
Schistosoma mansoni neuropeptide receptor 0.0012 0.0047 0.0041
Echinococcus granulosus dnaJ subfamily B 0.0494 0.5005 0.5072
Onchocerca volvulus Peroxidasin homolog 0.0064 0.0578 0.6603
Schistosoma mansoni hypothetical protein 0.0024 0.0167 0.0163
Trypanosoma cruzi Protein prenyltransferase alpha subunit repeat, putative 0.0022 0.0152 0.3816
Toxoplasma gondii prenyltransferase and squalene oxidase repeat-containing protein 0.001 0.0029 0.005
Schistosoma mansoni receptor protein tyrosine phosphatase r (pcptp1) 0.0025 0.0184 0.018
Entamoeba histolytica malate dehydrogenase, putative 0.0025 0.0181 0.2044
Loa Loa (eye worm) protein-tyrosine phosphatase 0.0025 0.0184 0.018
Echinococcus multilocularis peptidase Clp (S14 family) 0.0016 0.0082 0.0075
Onchocerca volvulus 0.0025 0.0184 0.2048
Trypanosoma cruzi hypothetical protein, conserved 0.0012 0.0044 0.0741
Toxoplasma gondii phosphofructokinase PFKII 0.001 0.0026 0.0043
Trichomonas vaginalis phosphofructokinase, putative 0.0037 0.0306 0.2618
Loa Loa (eye worm) hypothetical protein 0.0012 0.0047 0.0041
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0012 0.0047 0.0041
Onchocerca volvulus 0.0025 0.0184 0.2048
Schistosoma mansoni receptor protein tyrosine phosphatase n (ia2) 0.0025 0.0184 0.018
Trypanosoma brucei Protein prenyltransferase alpha subunit repeat, putative 0.0022 0.0152 0.3816
Trypanosoma cruzi protein farnesyltransferase alpha subunit, putative 0.0022 0.0152 0.3816
Loa Loa (eye worm) hypothetical protein 0.0012 0.0047 0.0041
Schistosoma mansoni biogenic amine (5HT) receptor 0.0012 0.0047 0.0041
Loa Loa (eye worm) hypothetical protein 0.0064 0.0578 0.058
Echinococcus multilocularis growth hormone secretagogue receptor type 1 0.0012 0.0047 0.004
Echinococcus granulosus nibrin 0.0012 0.0044 0.0038
Loa Loa (eye worm) hypothetical protein 0.0012 0.0044 0.0038
Schistosoma mansoni neuropeptide F-like receptor 0.0012 0.0047 0.0041
Trichomonas vaginalis conserved hypothetical protein 0.0012 0.0044 0.0358
Mycobacterium ulcerans NAD-dependent DNA ligase LigA 0.0012 0.0044 0.0047
Echinococcus multilocularis peptide (allatostatin:somatostatin) 0.0012 0.0047 0.004
Schistosoma mansoni peptide (FMRFamide/neurokinin-3)-like receptor 0.0012 0.0047 0.0041
Onchocerca volvulus 0.0012 0.0044 0.0434
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.001 0.0025 0.0019
Echinococcus granulosus arachidonate 5 lipoxygenase 0.0067 0.0608 0.061
Onchocerca volvulus Chorion peroxidase homolog 0.0064 0.0578 0.6603
Toxoplasma gondii GTP-binding nuclear protein ran/tc4 0.0009 0.0018 0.0026
Echinococcus granulosus receptor type tyrosine protein phosphatase 0.0025 0.0184 0.018
Plasmodium falciparum protein farnesyltransferase subunit alpha 0.0075 0.0696 1
Trypanosoma cruzi lanosterol synthase, putative 0.0011 0.004 0.061
Brugia malayi Protein-tyrosine phosphatase containing protein 0.0025 0.0184 0.018
Echinococcus granulosus receptor type tyrosine protein phosphatase zeta 0.0025 0.0184 0.018
Brugia malayi Protein prenyltransferase alpha subunit repeat containing protein 0.0022 0.0152 0.0148
Echinococcus multilocularis replication factor c subunit 1 0.0012 0.0044 0.0038
Brugia malayi glutaminase DH11.1 0.0121 0.1163 0.1173
Trichomonas vaginalis conserved hypothetical protein 0.0012 0.0044 0.0358
Echinococcus granulosus snurportin 1 0.0136 0.1319 0.1332
Brugia malayi Protein-tyrosine phosphatase 0.0025 0.0184 0.018
Brugia malayi Protein-tyrosine phosphatase containing protein 0.0025 0.0184 0.018
Brugia malayi G-protein coupled receptor 0.0012 0.0047 0.0041
Brugia malayi Protein-tyrosine phosphatase containing protein 0.0025 0.0184 0.018
Trypanosoma cruzi protein farnesyltransferase, putative 0.001 0.0029 0.0313
Onchocerca volvulus 0.0043 0.0369 0.419
Trichomonas vaginalis malate and lactate dehydrogenase, putative 0.001 0.0023 0.0172
Brugia malayi hypothetical protein 0.0087 0.0816 0.0821
Echinococcus granulosus malate dehydrogenase 0.001 0.0023 0.0016
Echinococcus multilocularis receptor type tyrosine protein phosphatase protein tyrosine phosphatase receptor type 0.0025 0.0184 0.0177
Trichomonas vaginalis replication factor C large subunit, putative 0.0012 0.0044 0.0358
Brugia malayi Protein-tyrosine phosphatase containing protein 0.0025 0.0184 0.018
Loa Loa (eye worm) hypothetical protein 0.0012 0.0047 0.0041
Trichomonas vaginalis geranylgeranyl transferase type II beta subunit, putative 0.001 0.0029 0.0228
Trichomonas vaginalis phosphofructokinase, putative 0.0037 0.0306 0.2618
Onchocerca volvulus 0.0012 0.0047 0.0462
Trichomonas vaginalis malate dehydrogenase, putative 0.001 0.0023 0.0172
Echinococcus multilocularis thyrotropin releasing hormone receptor 0.0012 0.0047 0.004
Echinococcus granulosus rhodopsin orphan GPCR 0.0012 0.0047 0.0041
Entamoeba histolytica hypothetical protein 0.0087 0.0816 1
Trichomonas vaginalis conserved hypothetical protein 0.0012 0.0044 0.0358
Loa Loa (eye worm) neuropeptide F receptor 0.0012 0.0047 0.0041
Schistosoma mansoni hypothetical protein 0.0012 0.0047 0.0041
Echinococcus multilocularis dro:myosuppressin receptor 0.0012 0.0047 0.004
Loa Loa (eye worm) hypothetical protein 0.0024 0.0166 0.0162
Onchocerca volvulus 0.0012 0.0047 0.0462
Mycobacterium leprae PROBABLE DNA LIGASE [NAD DEPENDENT] LIGA (POLYDEOXYRIBONUCLEOTIDE SYNTHASE [NAD+]) 0.0012 0.0044 0.0083
Echinococcus multilocularis sex peptide receptor 0.0012 0.0047 0.004
Brugia malayi Dopamine receptor protein 1 0.0012 0.0047 0.0041
Echinococcus multilocularis tyrosine protein phosphatase non receptor type 0.0028 0.0209 0.0203
Echinococcus granulosus alpha 1A adrenergic receptor 0.0012 0.0047 0.0041
Onchocerca volvulus Peroxidase homolog 0.0064 0.0578 0.6603
Mycobacterium tuberculosis Probable esterase LipL 0.0043 0.0369 0.1257
Brugia malayi AKH receptor 0.0012 0.0047 0.0041
Schistosoma mansoni ap endonuclease 0.0022 0.0143 0.0139
Loa Loa (eye worm) hypothetical protein 0.0012 0.0047 0.0041
Brugia malayi hypothetical protein 0.0024 0.0167 0.0163
Schistosoma mansoni cpg binding protein 0.0037 0.0299 0.0297
Mycobacterium leprae PROBABLE MALATE DEHYDROGENASE MDH 0.001 0.0023 0.0036
Echinococcus multilocularis protein tyrosine phosphatase n9 0.0025 0.0184 0.0177
Echinococcus multilocularis snurportin 1 0.0136 0.1319 0.1313
Schistosoma mansoni receptor tyrosine phosphatase type r2a 0.0025 0.0184 0.018
Loa Loa (eye worm) follicle stimulating hormone receptor 0.0012 0.0047 0.0041
Chlamydia trachomatis phosphoshikimate 1-carboxyl vinyltransferase 0.0456 0.462 1
Brugia malayi Protein-tyrosine phosphatase containing protein 0.0025 0.0184 0.018
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0012 0.0047 0.0041
Brugia malayi Protein-tyrosine phosphatase containing protein 0.0092 0.0872 0.0878
Brugia malayi Tachykinin-like peptides receptor 99D 0.0012 0.0047 0.0041
Loa Loa (eye worm) hypothetical protein 0.0025 0.0184 0.018
Mycobacterium ulcerans beta-lactamase 0.0043 0.0369 0.0754
Loa Loa (eye worm) hypothetical protein 0.0043 0.0369 0.0368
Mycobacterium tuberculosis Halimadienyl diphosphate synthase 0.0011 0.004 0.0061
Echinococcus multilocularis 6 phosphofructokinase 0.0037 0.0306 0.03
Brugia malayi topoisomerase 0.0012 0.0044 0.0038
Echinococcus multilocularis importin subunit beta 1 0.0013 0.0053 0.0046
Plasmodium vivax 6-phosphofructokinase, putative 0.001 0.0026 0.0369
Echinococcus multilocularis biogenic amine (5HT) receptor 0.0012 0.0047 0.004
Toxoplasma gondii malate dehydrogenase MDH 0.0025 0.0181 0.038
Onchocerca volvulus 0.0012 0.0047 0.0462
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0012 0.0047 0.0041
Plasmodium falciparum geranylgeranyl transferase type-2 subunit alpha, putative 0.0022 0.0152 0.2117
Mycobacterium ulcerans esterase/lipase LipP 0.0043 0.0369 0.0754
Toxoplasma gondii ATPase, AAA family protein 0.0012 0.0044 0.0083
Schistosoma mansoni neuropeptide receptor 0.0012 0.0047 0.0041
Brugia malayi ORL1-like opioid receptor 0.0012 0.0047 0.0041
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0012 0.0047 0.0041
Loa Loa (eye worm) hypothetical protein 0.0025 0.0184 0.018
Loa Loa (eye worm) hypothetical protein 0.0064 0.0578 0.058
Loa Loa (eye worm) hypothetical protein 0.0012 0.0047 0.0041
Echinococcus multilocularis malate dehydrogenase 0.001 0.0023 0.0016
Plasmodium vivax lactate/malate dehydrogenase, putative 0.001 0.0023 0.0325
Schistosoma mansoni hypothetical protein 0.0018 0.0107 0.0102
Brugia malayi Unidentified vitellogenin-linked transcript protein 6, putative 0.0012 0.0047 0.0041
Echinococcus multilocularis neuropeptide Y receptor 0.0012 0.0047 0.004
Loa Loa (eye worm) hypothetical protein 0.0024 0.0167 0.0163
Onchocerca volvulus 0.0025 0.0184 0.2048
Brugia malayi Animal haem peroxidase family protein 0.0064 0.0578 0.058
Brugia malayi G-protein-linked acetylcholine receptor protein 2, putative 0.0012 0.0047 0.0041
Trichomonas vaginalis conserved hypothetical protein 0.0012 0.0044 0.0358
Brugia malayi Protein-tyrosine phosphatase containing protein 0.0025 0.0184 0.018
Echinococcus granulosus cytosolic malate dehydrogenase 0.001 0.0023 0.0016
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0012 0.0047 0.0041
Trichomonas vaginalis RNA polymerase II ctd phosphatase, putative 0.0012 0.0044 0.0358
Trichomonas vaginalis D-aminoacylase, putative 0.0043 0.0369 0.3161
Echinococcus multilocularis receptor type tyrosine protein phosphatase 0.0025 0.0184 0.0177
Brugia malayi Protein-tyrosine phosphatase containing protein 0.0025 0.0184 0.018
Leishmania major GTP-binding protein, putative 0.0009 0.0018 0.0215
Schistosoma mansoni hypothetical protein 0.0018 0.0107 0.0102
Echinococcus multilocularis protein farnesyltransferase alpha subunit 0.0075 0.0696 0.069
Loa Loa (eye worm) 6-phosphofructokinase 0.0037 0.0306 0.0304
Echinococcus granulosus Receptor type tyrosine protein phosphatase O 0.0025 0.0184 0.018
Loa Loa (eye worm) hypothetical protein 0.0025 0.0181 0.0177
Brugia malayi gonadotropin-releasing hormone receptor 2 0.0012 0.0047 0.0041
Trichomonas vaginalis phosphofructokinase, putative 0.0037 0.0306 0.2618
Toxoplasma gondii hypothetical protein 0.0053 0.0466 0.0997
Treponema pallidum ATP-dependent Clp protease proteolytic subunit 0.0024 0.0166 0.0575
Loa Loa (eye worm) hypothetical protein 0.0012 0.0047 0.0041
Echinococcus granulosus g protein coupled receptor 0.0012 0.0047 0.0041
Mycobacterium ulcerans 3-dehydroquinate synthase 0.0178 0.175 0.3759
Mycobacterium tuberculosis Probable hydrolase 0.0043 0.0369 0.1257
Onchocerca volvulus 0.0043 0.0369 0.419
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.0022 0.0143 0.0139
Trichomonas vaginalis malate dehydrogenase, putative 0.001 0.0023 0.0172
Brugia malayi Protein-tyrosine phosphatase containing protein 0.0028 0.0209 0.0205
Loa Loa (eye worm) G-protein-linked acetylcholine receptor protein 2 0.0012 0.0047 0.0041
Giardia lamblia Prenyltransferase 0.001 0.0029 0.0326
Plasmodium vivax farnesyltransferase beta subunit, putative 0.001 0.0029 0.0418
Brugia malayi hypothetical protein 0.0025 0.0184 0.018
Loa Loa (eye worm) hypothetical protein 0.0012 0.0047 0.0041
Echinococcus granulosus 6 phosphofructokinase 0.0037 0.0306 0.0304
Onchocerca volvulus 0.0075 0.0689 0.7881
Echinococcus multilocularis Receptor type tyrosine protein phosphatase O 0.0025 0.0184 0.0177
Loa Loa (eye worm) hypothetical protein 0.0064 0.0578 0.058
Echinococcus granulosus neuropeptide receptor 0.0012 0.0047 0.0041
Echinococcus granulosus neuropeptide s receptor 0.0012 0.0047 0.0041
Trichomonas vaginalis malate dehydrogenase, putative 0.001 0.0023 0.0172
Schistosoma mansoni hypothetical protein 0.0494 0.5005 0.5072
Loa Loa (eye worm) hypothetical protein 0.0012 0.0047 0.0041
Plasmodium vivax malate dehydrogenase, putative 0.0025 0.0181 0.2603
Giardia lamblia GTP-binding nuclear protein RAN/TC4 0.0009 0.0018 0.0167
Schistosoma mansoni malate dehydrogenase 0.0025 0.0181 0.0177
Loa Loa (eye worm) hypothetical protein 0.006 0.0536 0.0538
Schistosoma mansoni rab6-interacting 0.0024 0.0167 0.0163
Schistosoma mansoni hypothetical protein 0.0018 0.0107 0.0102
Onchocerca volvulus 0.0012 0.0047 0.0462
Loa Loa (eye worm) protein-tyrosine phosphatase 0.0025 0.0184 0.018
Schistosoma mansoni hypothetical protein 0.0039 0.0323 0.0321
Entamoeba histolytica phosphofructokinase, putative 0.0037 0.0306 0.3611
Loa Loa (eye worm) hypothetical protein 0.0064 0.0578 0.058
Echinococcus multilocularis protein prenyltransferase alpha subunit 0.0022 0.0152 0.0146
Loa Loa (eye worm) beta-lactamase 0.0043 0.0369 0.0368
Trypanosoma brucei Protein prenyltransferase alpha subunit repeat, putative 0.0022 0.0152 0.3816
Echinococcus granulosus g-protein coupled receptor 0.0012 0.0047 0.0041
Onchocerca volvulus Neurogenic locus notch homolog 0.0008 0.0007 0.0005
Echinococcus granulosus receptor type tyrosine protein phosphatase 0.0025 0.0184 0.018
Onchocerca volvulus 0.0012 0.0047 0.0462
Toxoplasma gondii phosphofructokinase domain-containing protein 0.001 0.0026 0.0043
Echinococcus granulosus geranylgeranyl transferase type 2 subunit alpha 0.0022 0.0152 0.0148
Brugia malayi Dopamine receptor 0.0012 0.0047 0.0041
Trypanosoma brucei importin beta-1 subunit, putative 0.0013 0.0053 0.0984
Trichomonas vaginalis malate dehydrogenase, putative 0.001 0.0023 0.0172
Schistosoma mansoni non-receptor protein-tyrosine phosphatase 0.0025 0.0184 0.018
Leishmania major cytosolic malate dehydrogenase 0.001 0.0023 0.0341
Echinococcus multilocularis serotonin receptor 0.0012 0.0047 0.004
Loa Loa (eye worm) hypothetical protein 0.0012 0.0047 0.0041
Mycobacterium ulcerans lipase LipD 0.0043 0.0369 0.0754
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0009 0.0014 0.0007
Echinococcus granulosus L lactate dehydrogenase B chain 0.0025 0.0181 0.0177
Echinococcus granulosus g protein coupled receptor 0.0012 0.0047 0.0041
Echinococcus granulosus mixed lineage leukemia protein mll 0.0009 0.0014 0.0007
Toxoplasma gondii histone lysine methyltransferase SET1 0.0066 0.0602 0.1291
Echinococcus multilocularis 7TM GPCR, rhodopsin 0.0012 0.0047 0.004
Brugia malayi protein-tyrosine phosphatase Lar-like precursor, putative 0.0025 0.0184 0.018
Brugia malayi Peroxidasin 0.0064 0.0578 0.058
Schistosoma mansoni receptor tyrosine phosphatase type r2a 0.0025 0.0184 0.018
Schistosoma mansoni 6-phosphofructokinase 0.0037 0.0306 0.0304
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0009 0.0014 0.0007
Leishmania major protein farnesyltransferase alpha subunit, putative 0.0022 0.0152 0.3949
Plasmodium vivax replication factor C subunit 1, putative 0.0012 0.0044 0.0634
Trichomonas vaginalis D-aminoacylase, putative 0.0043 0.0369 0.3161
Loa Loa (eye worm) hypothetical protein 0.0012 0.0047 0.0041
Trichomonas vaginalis malate dehydrogenase, putative 0.001 0.0023 0.0172
Onchocerca volvulus 0.001 0.0025 0.0215
Plasmodium vivax GTP-binding nuclear protein RAN/TC4, putative 0.0009 0.0018 0.026
Leishmania major farnesyltransferase beta subunit 0.001 0.0029 0.0521
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0012 0.0047 0.0041
Brugia malayi Protein-tyrosine phosphatase 0.0025 0.0184 0.018
Treponema pallidum DNA ligase (lig) 0.0012 0.0044 0.0137
Brugia malayi EGF-like domain containing protein 0.0008 0.0007 0.0000000067736
Loa Loa (eye worm) hypothetical protein 0.0025 0.0184 0.018
Schistosoma mansoni receptor tyrosine phosphatase type r2a 0.0025 0.0184 0.018
Loa Loa (eye worm) protein-tyrosine phosphatase 0.0966 0.9863 1
Toxoplasma gondii 6-phosphofructokinase 0.001 0.0026 0.0043
Schistosoma mansoni peptidase Clp (S14 family) 0.0024 0.0166 0.0162
Loa Loa (eye worm) hypothetical protein 0.0012 0.0047 0.0041
Loa Loa (eye worm) hypothetical protein 0.0012 0.0047 0.0041
Wolbachia endosymbiont of Brugia malayi malate dehydrogenase 0.0025 0.0181 0.0499
Echinococcus multilocularis g protein coupled receptor 0.0012 0.0047 0.004
Entamoeba histolytica phosphofructokinase, putative 0.0037 0.0306 0.3611
Brugia malayi Prenyltransferase and squalene oxidase repeat family protein 0.001 0.0029 0.0023
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.001 0.0025 0.0019
Loa Loa (eye worm) sex muscle abnormal protein 5 0.0049 0.043 0.043
Treponema pallidum diphosphate--fructose-6-phosphate 1-phosphotransferase 0.0037 0.0306 0.1078
Loa Loa (eye worm) hypothetical protein 0.0012 0.0047 0.0041
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0012 0.0047 0.0041
Brugia malayi Animal haem peroxidase family protein 0.0064 0.0578 0.058
Echinococcus granulosus hypothetical protein 0.0012 0.0047 0.0041
Brugia malayi hypothetical protein 0.0012 0.0047 0.0041
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0012 0.0047 0.0041
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0018 0.0107 0.0102
Trypanosoma cruzi cytosolic malate dehydrogenase, putative 0.001 0.0023 0.0129
Echinococcus multilocularis receptor type tyrosine protein phosphatase 0.0025 0.0184 0.0177
Toxoplasma gondii exonuclease III APE 0.0022 0.0143 0.0297
Onchocerca volvulus 0.0035 0.0279 0.3144
Trypanosoma cruzi lanosterol synthase, putative 0.0011 0.004 0.061
Brugia malayi hypothetical protein 0.0064 0.0578 0.058
Leishmania major importin beta-1 subunit, putative 0.001 0.0028 0.0488
Entamoeba histolytica hypothetical protein 0.0087 0.0816 1
Schistosoma mansoni neuropeptide F-like receptor 0.0012 0.0047 0.0041
Entamoeba histolytica hypothetical protein 0.0012 0.0044 0.0326
Echinococcus granulosus neurogenic locus notch protein 0.0008 0.0007 0.0000000067736
Loa Loa (eye worm) hypothetical protein 0.0012 0.0044 0.0038
Loa Loa (eye worm) hypothetical protein 0.0012 0.0047 0.0041
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.001 0.0025 0.0019

Activities

Activity type Activity value Assay description Source Reference
IC50 (functional) = 6.11 uM PubChem BioAssay. Dose Response Confirmation of SKN-1 Inhibitor hits in a fluorescence ratio assay. (Class of assay: confirmatory) ChEMBL. No reference
IC50 (functional) = 10.6 uM PubChem BioAssay. Dose ResponseConfirmation of SKN-1 Inhibitor hits in a fluorescence ratio assay - Set 2. (Class of assay: confirmatory) ChEMBL. No reference
IC50 (functional) = 48.4 uM PubChem BioAssay. Dose Response Confirmation of SKN-1 Inhibitor hits via a heat-shock counterscreen assay. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) = 0.3162 um PUBCHEM_BIOASSAY: qHTS Inhibitors of AmpC Beta-Lactamase (assay with detergent). (Class of assay: confirmatory) [Related pubchem assays: 1002 (Confirmation Concentration-Response Assay for Inhibitors of AmpC Beta-Lactamase (assay with detergent)), 585 (Promiscuous and Specific Inhibitors of AmpC Beta-Lactamase (assay without detergent) - a screen old NIH MLSMR collection), 584 (Promiscuous and Specific Inhibitors of AmpC Beta-Lactamase (assay with detergent) - a screen of the old NIH MLSMR collection), 1003 (Confirmation Cuvette-Based Assay for Inhibitors of AmpC Beta-Lactamase (assay with detergent))] ChEMBL. No reference
Potency (functional) 8.1995 uM PUBCHEM_BIOASSAY: qHTS screen for small molecules that induce genotoxicity in human embryonic kidney (HEK293T) cells expressing luciferase-tagged ELG1. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID493106, AID493143] ChEMBL. No reference
Potency (functional) 9.285 uM PUBCHEM_BIOASSAY: Primary qHTS for delayed death inhibitors of the malarial parasite plastid, 48 hour incubation. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID488752, AID488774, AID504848, AID504850] ChEMBL. No reference
Potency (functional) = 10 um PUBCHEM_BIOASSAY: qHTS Assay for Inhibitors of Influenza NS1 Protein Function. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) = 10 um PUBCHEM_BIOASSAY: qHTS Assay for Inhibitors of 15-hLO (15-human lipoxygenase). (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) 10 uM PubChem BioAssay. qHTS Assay to Identify Small Molecule Activators of BRCA1 Expression. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) 13.1154 uM PUBCHEM_BIOASSAY: Primary qHTS for delayed death inhibitors of the malarial parasite plastid, 96 hour incubation. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID488745, AID488752, AID488774, AID504848, AID504850] ChEMBL. No reference
Potency (functional) = 14.1254 um PUBCHEM_BIOASSAY: qHTS Assay for Inhibitors Targeting the Menin-MLL Interaction in MLL Related Leukemias: Competition With Texas Red Labeled MLL-derived Mutant Peptide. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) 15.8489 uM PUBCHEM_BIOASSAY: qHTS assay for re-activators of p53 using a Luc reporter. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID504709] ChEMBL. No reference
Potency (functional) 16.3601 uM PUBCHEM_BIOASSAY: Nrf2 qHTS screen for inhibitors. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID493153, AID493163, AID504648] ChEMBL. No reference
Potency (functional) 16.3601 uM PUBCHEM_BIOASSAY: qHTS screen for small molecules that inhibit ELG1-dependent DNA repair in human embryonic kidney (HEK293T) cells expressing luciferase-tagged ELG1. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID493107, AID493125] ChEMBL. No reference
Potency (functional) 22.3872 uM PubChem BioAssay. qHTS for induction of synthetic lethality in tumor cells producing 2HG: qHTS for the HT-1080-NT fibrosarcoma cell line. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) 23.9341 uM PUBCHEM_BIOASSAY: qHTS profiling assay for firefly luciferase inhibitor/activator using purified enzyme and Km concentrations of substrates (counterscreen for miR-21 project). (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID2288, AID2289, AID2598, AID411] ChEMBL. No reference
Potency (functional) = 25.1189 um PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Thyroid Stimulating Hormone Receptor. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) = 25.1189 um PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Thyroid Stimulating Hormone Receptor: Activators of Intracellular cAMP Concentrations in Parental HEK 293. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) 28.1838 uM PubChem BioAssay. qHTS of GLP-1 Receptor Inverse Agonists (Inhibition Mode). (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) 28.1838 uM PubChem BioAssay. qHTS Assay for Inhibitors of the HIV-1 protein Vpr. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) = 35.4813 um PUBCHEM_BIOASSAY: qHTS for inhibitors of ROR gamma transcriptional activity. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) 56.2341 uM PUBCHEM_BIOASSAY: qHTS Assay for Inhibitors of JMJD2A-Tudor Domain. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID504402] ChEMBL. No reference
Potency (functional) 79.4328 uM PUBCHEM_BIOASSAY: qHTS Assay for Inhibitors of BAZ2B. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID504391] ChEMBL. No reference
Potency (functional) 89.1251 uM PUBCHEM_BIOASSAY: qHTS Assay for Inhibitors of Histone Lysine Methyltransferase G9a. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID504404] ChEMBL. No reference

Phenotypes

Whole-cell/tissue/organism interactions

Species name Source Reference Is orphan
Plasmodium falciparum ChEMBL23

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

No literature references available for this target.

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