Detailed information for compound 1384803

Basic information

Technical information
  • TDR Targets ID: 1384803
  • Name: N-(3-hydroxypyridin-2-yl)-4-(phenoxy)benzamid e
  • MW: 306.315 | Formula: C18H14N2O3
  • H donors: 2 H acceptors: 3 LogP: 3.19 Rotable bonds: 5
    Rule of 5 violations (Lipinski): 1
  • SMILES: O=C(c1ccc(cc1)Oc1ccccc1)Nc1ncccc1O
  • InChi: 1S/C18H14N2O3/c21-16-7-4-12-19-17(16)20-18(22)13-8-10-15(11-9-13)23-14-5-2-1-3-6-14/h1-12,21H,(H,19,20,22)
  • InChiKey: HDVVWQQDMUWDIT-UHFFFAOYSA-N  


Substructure search Similarity search

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Synonyms

  • N-(3-hydroxy-2-pyridyl)-4-(phenoxy)benzamide
  • Enamine_003856
  • IDI1_007499
  • T0510-1963

Targets

Known targets for this compound

Species Target name Source Bibliographic reference
Homo sapiens nuclear factor, erythroid 2-like 2 Starlite/ChEMBL No references
Homo sapiens glycoprotein hormones, alpha polypeptide Starlite/ChEMBL No references
Homo sapiens glucagon-like peptide 1 receptor Starlite/ChEMBL No references
Homo sapiens Niemann-Pick disease, type C1 Starlite/ChEMBL No references
Mus musculus RAR-related orphan receptor gamma Starlite/ChEMBL No references
Photinus pyralis Luciferin 4-monooxygenase Starlite/ChEMBL No references
Homo sapiens ATM serine/threonine kinase Starlite/ChEMBL No references
Homo sapiens RAB9A, member RAS oncogene family Starlite/ChEMBL No references
Influenza A virus Nonstructural protein 1 Starlite/ChEMBL No references
Homo sapiens ATPase family, AAA domain containing 5 Starlite/ChEMBL No references

Predicted pathogen targets for this compound

By orthology
Species Potential target Known druggable target/s Ortholog Group
Trypanosoma cruzi phosphatidylinositol kinase related protein, putative Get druggable targets OG5_128955 All targets in OG5_128955
Trypanosoma brucei gambiense phosphatidylinositol kinase domain protein, putative Get druggable targets OG5_128955 All targets in OG5_128955
Plasmodium knowlesi acyl-CoA synthetase, putative Get druggable targets OG5_126609 All targets in OG5_126609
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD7 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) Get druggable targets OG5_126609 All targets in OG5_126609
Mycobacterium ulcerans acyl-CoA synthetase Get druggable targets OG5_126609 All targets in OG5_126609
Mycobacterium tuberculosis Probable chain -fatty-acid-CoA ligase FadD13 (fatty-acyl-CoA synthetase) Get druggable targets OG5_126609 All targets in OG5_126609
Candida albicans identical to the C terminus of CaP19.5580 potential phosphatidylinositol kinase Get druggable targets OG5_128955 All targets in OG5_128955
Leishmania major 4-coumarate:coa ligase-like protein Get druggable targets OG5_126609 All targets in OG5_126609
Schistosoma japonicum Niemann-Pick C1 protein precursor, putative Get druggable targets OG5_128206 All targets in OG5_128206
Brugia malayi AMP-binding enzyme family protein Get druggable targets OG5_126609 All targets in OG5_126609
Mycobacterium ulcerans acyl-CoA synthetase Get druggable targets OG5_126609 All targets in OG5_126609
Echinococcus granulosus Niemann Pick C1 protein Get druggable targets OG5_128206 All targets in OG5_128206
Brugia malayi AMP-binding enzyme family protein Get druggable targets OG5_126609 All targets in OG5_126609
Leishmania mexicana 4-coumarate:coa ligase-like protein Get druggable targets OG5_126609 All targets in OG5_126609
Leishmania infantum 4-coumarate:coa ligase-like protein Get druggable targets OG5_126609 All targets in OG5_126609
Leishmania infantum 4-coumarate:coa ligase-like protein Get druggable targets OG5_126609 All targets in OG5_126609
Trypanosoma cruzi phosphatidylinositol kinase related protein, putative Get druggable targets OG5_128955 All targets in OG5_128955
Mycobacterium ulcerans long-chain-fatty-acid--CoA ligase Get druggable targets OG5_126609 All targets in OG5_126609
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_126609 All targets in OG5_126609
Schistosoma mansoni niemann-pick C1 (NPC1) Get druggable targets OG5_128206 All targets in OG5_128206
Schistosoma japonicum Niemann-Pick C1 protein precursor, putative Get druggable targets OG5_128206 All targets in OG5_128206
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_128206 All targets in OG5_128206
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_126609 All targets in OG5_126609
Toxoplasma gondii FATC domain-containing protein Get druggable targets OG5_128955 All targets in OG5_128955
Leishmania major phosphatidylinositol kinase related protein, putative Get druggable targets OG5_128955 All targets in OG5_128955
Mycobacterium ulcerans acyl-CoA synthetase Get druggable targets OG5_126609 All targets in OG5_126609
Leishmania major 4-coumarate:coa ligase-like protein Get druggable targets OG5_126609 All targets in OG5_126609
Neospora caninum phosphatidylinositol 3- and 4-kinase domain- containing protein, putative Get druggable targets OG5_128955 All targets in OG5_128955
Entamoeba histolytica acyl-CoA synthetase, putative Get druggable targets OG5_126609 All targets in OG5_126609
Leishmania major 4-coumarate:coa ligase-like protein Get druggable targets OG5_126609 All targets in OG5_126609
Mycobacterium tuberculosis Fatty-acid-AMP ligase FadD30 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) Get druggable targets OG5_126609 All targets in OG5_126609
Leishmania donovani 4-coumarate:coa ligase-like protein Get druggable targets OG5_126609 All targets in OG5_126609
Trypanosoma brucei phosphatidylinositol kinase related protein, putative Get druggable targets OG5_128955 All targets in OG5_128955
Leishmania braziliensis 4-coumarate:coa ligase-like protein Get druggable targets OG5_126609 All targets in OG5_126609
Schistosoma japonicum IPR000971,Globin;IPR012292,Globin-related;IPR009050,Globin-like,domain-containing Get druggable targets OG5_128955 All targets in OG5_128955
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_126609 All targets in OG5_126609
Entamoeba histolytica Niemann-Pick C1 protein, putative Get druggable targets OG5_128206 All targets in OG5_128206
Schistosoma japonicum ko:K04728 ataxia telangectasia mutated family protein, putative Get druggable targets OG5_128955 All targets in OG5_128955
Candida albicans similar to putative phosphatidylinositol kinase involved in telomere length regulation Get druggable targets OG5_128955 All targets in OG5_128955
Echinococcus granulosus Niemann Pick C1 protein Get druggable targets OG5_128206 All targets in OG5_128206
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_128206 All targets in OG5_128206
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_126609 All targets in OG5_126609
Mycobacterium ulcerans fatty-acid-CoA ligase Get druggable targets OG5_126609 All targets in OG5_126609
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_126609 All targets in OG5_126609
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_126609 All targets in OG5_126609
Leishmania mexicana 4-coumarate:coa ligase-like protein Get druggable targets OG5_126609 All targets in OG5_126609
Trypanosoma cruzi phosphatidylinositol kinase related protein, putative Get druggable targets OG5_128955 All targets in OG5_128955
Schistosoma japonicum ko:K07003 Niemann Pick type C1, putative Get druggable targets OG5_128206 All targets in OG5_128206
Trichomonas vaginalis PIKK family atypical protein kinase Get druggable targets OG5_128955 All targets in OG5_128955
Schistosoma japonicum hypothetical protein Get druggable targets OG5_128955 All targets in OG5_128955
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_128955 All targets in OG5_128955
Echinococcus multilocularis atpase aaa+ type core atpase aaa type core Get druggable targets OG5_139225 All targets in OG5_139225
Leishmania mexicana 4-coumarate:coa ligase-like protein Get druggable targets OG5_126609 All targets in OG5_126609
Entamoeba histolytica hypothetical protein Get druggable targets OG5_128955 All targets in OG5_128955
Brugia malayi Niemann-Pick C1 protein precursor Get druggable targets OG5_128206 All targets in OG5_128206
Leishmania infantum 4-coumarate:coa ligase-like protein Get druggable targets OG5_126609 All targets in OG5_126609
Entamoeba histolytica acyl-CoA synthetase, putative Get druggable targets OG5_126609 All targets in OG5_126609
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD3 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) Get druggable targets OG5_126609 All targets in OG5_126609
Leishmania donovani 4-coumarate:coa ligase-like protein Get druggable targets OG5_126609 All targets in OG5_126609
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD2 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) Get druggable targets OG5_126609 All targets in OG5_126609
Plasmodium vivax acyl-CoA synthetase, putative Get druggable targets OG5_126609 All targets in OG5_126609
Leishmania donovani phosphatidylinositol 3-kinase-like protein Get druggable targets OG5_128955 All targets in OG5_128955
Brugia malayi AMP-binding enzyme family protein Get druggable targets OG5_126609 All targets in OG5_126609
Chlamydia trachomatis acylglycerophosphoethanolamine acyltransferase Get druggable targets OG5_126609 All targets in OG5_126609
Onchocerca volvulus Get druggable targets OG5_126609 All targets in OG5_126609
Mycobacterium ulcerans fatty-acid-CoA ligase Get druggable targets OG5_126609 All targets in OG5_126609
Leishmania mexicana phosphatidylinositol 3-kinase-like protein Get druggable targets OG5_128955 All targets in OG5_128955
Leishmania infantum phosphatidylinositol kinase related protein, putative Get druggable targets OG5_128955 All targets in OG5_128955
Echinococcus granulosus expressed conserved protein Get druggable targets OG5_128206 All targets in OG5_128206
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_126609 All targets in OG5_126609
Plasmodium falciparum acyl-CoA synthetase Get druggable targets OG5_126609 All targets in OG5_126609
Mycobacterium ulcerans long-chain-fatty-acid-CoA ligase Get druggable targets OG5_126609 All targets in OG5_126609
Plasmodium yoelii peroxisomal-coenzyme a synthetase Get druggable targets OG5_126609 All targets in OG5_126609
Echinococcus multilocularis expressed conserved protein Get druggable targets OG5_128206 All targets in OG5_128206
Entamoeba histolytica acyl-coA synthetase, putative Get druggable targets OG5_126609 All targets in OG5_126609
Echinococcus multilocularis Niemann Pick C1 protein Get druggable targets OG5_128206 All targets in OG5_128206
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein Get druggable targets OG5_128955 All targets in OG5_128955
Candida albicans similar to putative phosphatidylinositol kinase involved in telomere length regulation Get druggable targets OG5_128955 All targets in OG5_128955
Leishmania infantum 4-coumarate:coa ligase-like protein Get druggable targets OG5_126609 All targets in OG5_126609
Mycobacterium ulcerans long-chain fatty-acid CoA ligase Get druggable targets OG5_126609 All targets in OG5_126609
Leishmania braziliensis phosphatidylinositol kinase related protein, putative Get druggable targets OG5_128955 All targets in OG5_128955
Echinococcus granulosus serine protein kinase ATM Get druggable targets OG5_128955 All targets in OG5_128955
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD7 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) Get druggable targets OG5_126609 All targets in OG5_126609
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD2 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) Get druggable targets OG5_126609 All targets in OG5_126609
Echinococcus multilocularis serine protein kinase ATM Get druggable targets OG5_128955 All targets in OG5_128955
Schistosoma japonicum hypothetical protein Get druggable targets OG5_128955 All targets in OG5_128955
Schistosoma mansoni ataxia telangiectasia mutated (atm) Get druggable targets OG5_128955 All targets in OG5_128955
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD5 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) Get druggable targets OG5_126609 All targets in OG5_126609
Plasmodium berghei acyl-CoA synthetase, putative Get druggable targets OG5_126609 All targets in OG5_126609
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_126609 All targets in OG5_126609
Candida albicans potential membrane protein similar to S. cerevisiae NCR1 (YPL006W) and human NPC1 late endosomal protein involved in sterol home Get druggable targets OG5_128206 All targets in OG5_128206
Echinococcus multilocularis Niemann Pick C1 protein Get druggable targets OG5_128206 All targets in OG5_128206
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD35 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) Get druggable targets OG5_126609 All targets in OG5_126609
Mycobacterium ulcerans hypothetical protein Get druggable targets OG5_126609 All targets in OG5_126609
By sequence similarity to non orthologous known druggable targets
Species Potential target Known druggable target Length Alignment span Identity
Candida albicans similar to S. cerevisiae FAT1 (YBR041W) fatty acid transporter and very long-chain fatty acyl-CoA synthetase Luciferin 4-monooxygenase   550 aa 496 aa 24.2 %
Neospora caninum acetyl-coenzyme a synthetase, putative Luciferin 4-monooxygenase   550 aa 549 aa 20.9 %
Trypanosoma brucei gambiense fatty acyl CoA synthetase 3 Luciferin 4-monooxygenase   550 aa 491 aa 23.6 %
Leishmania braziliensis long-chain-fatty-acid-CoA ligase, putative Luciferin 4-monooxygenase   550 aa 504 aa 25.6 %
Mycobacterium ulcerans acyl-CoA synthetase Luciferin 4-monooxygenase   550 aa 582 aa 22.3 %
Dictyostelium discoideum hypothetical protein Luciferin 4-monooxygenase   550 aa 542 aa 22.1 %
Trypanosoma congolense fatty acyl CoA synthetase 2, putative Luciferin 4-monooxygenase   550 aa 500 aa 22.4 %
Schistosoma japonicum ko:K01897 long-chain fatty-acid-CoA ligase [EC6.2.1.3], putative Luciferin 4-monooxygenase   550 aa 541 aa 22.4 %
Leishmania donovani long chain fatty Acyl CoA synthetase, putative Luciferin 4-monooxygenase   550 aa 500 aa 23.4 %
Cryptosporidium hominis acetyl-CoenzymeA synthetase (acetate--coa ligase) (acyl-activating enzyme) Luciferin 4-monooxygenase   550 aa 549 aa 22.6 %
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein Luciferin 4-monooxygenase   550 aa 476 aa 22.5 %
Dictyostelium discoideum hypothetical protein Luciferin 4-monooxygenase   550 aa 478 aa 21.1 %
Mycobacterium tuberculosis Fatty-acid-AMP ligase FadD28 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) Luciferin 4-monooxygenase   550 aa 504 aa 22.6 %
Cryptosporidium hominis acyl-CoA synthetase Luciferin 4-monooxygenase   550 aa 460 aa 26.1 %
Mycobacterium tuberculosis Probable fatty-acid-AMP ligase FadD21 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) Luciferin 4-monooxygenase   550 aa 586 aa 24.4 %
Mycobacterium leprae PROBABLE FATTY-ACID--CoA LIGASE FADD21 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) Luciferin 4-monooxygenase   550 aa 565 aa 22.8 %
Dictyostelium discoideum AMP-dependent synthetase and ligase domain-containing protein Luciferin 4-monooxygenase   550 aa 517 aa 24.8 %
Leishmania major long chain fatty Acyl CoA synthetase, putative Luciferin 4-monooxygenase   550 aa 482 aa 23.2 %
Neospora caninum Short-chain dehydrogenase/reductase SDR, related Luciferin 4-monooxygenase   550 aa 518 aa 19.1 %
Mycobacterium tuberculosis Probable fatty-acid-AMP ligase FadD23 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) Luciferin 4-monooxygenase   550 aa 542 aa 23.8 %
Mycobacterium ulcerans long-chain-fatty-acid-CoA ligase, FadD11 Luciferin 4-monooxygenase   550 aa 492 aa 24.6 %
Dictyostelium discoideum acetyl-CoA ligase Luciferin 4-monooxygenase   550 aa 549 aa 22.2 %
Entamoeba histolytica long-chain-fatty-acid--CoA ligase, putative Luciferin 4-monooxygenase   550 aa 494 aa 23.9 %
Babesia bovis fatty acyl-CoA synthetase family protein Luciferin 4-monooxygenase   550 aa 461 aa 23.4 %
Onchocerca volvulus Luciferin 4-monooxygenase   550 aa 502 aa 24.9 %
Dictyostelium discoideum hypothetical protein Luciferin 4-monooxygenase   550 aa 538 aa 21.8 %
Trichomonas vaginalis antibiotic synthetase, putative Luciferin 4-monooxygenase   550 aa 581 aa 21.2 %
Trypanosoma brucei fatty acyl CoA synthetase 3 Luciferin 4-monooxygenase   550 aa 491 aa 23.6 %
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD9 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) Luciferin 4-monooxygenase   550 aa 480 aa 22.5 %
Leishmania mexicana long chain fatty Acyl CoA synthetase, putative Luciferin 4-monooxygenase   550 aa 483 aa 23.8 %
Dictyostelium discoideum hypothetical protein Luciferin 4-monooxygenase   550 aa 542 aa 18.3 %
Trichomonas vaginalis AMP dependent ligase/synthetase, putative Luciferin 4-monooxygenase   550 aa 554 aa 24.4 %
Trypanosoma cruzi fatty acyl CoA synthetase, putative Luciferin 4-monooxygenase   550 aa 480 aa 25.2 %
Trichomonas vaginalis AMP dependent CoA ligase, putative Luciferin 4-monooxygenase   550 aa 524 aa 24.0 %
Cryptosporidium parvum acetyl-coenzyme A synthetase Luciferin 4-monooxygenase   550 aa 545 aa 22.8 %
Mycobacterium leprae FATTY-ACID-CoA LIGASE FADD26 (FATTY-ACID-COA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) Luciferin 4-monooxygenase   550 aa 533 aa 22.7 %
Mycobacterium ulcerans non-ribosomal peptide synthetase Luciferin 4-monooxygenase   550 aa 541 aa 22.4 %
Trichomonas vaginalis AMP dependent ligase/synthetase, putative Luciferin 4-monooxygenase   550 aa 526 aa 22.4 %
Dictyostelium discoideum hypothetical protein Luciferin 4-monooxygenase   550 aa 499 aa 19.2 %
Mycobacterium ulcerans acyl-CoA synthetase Luciferin 4-monooxygenase   550 aa 593 aa 22.1 %
Mycobacterium ulcerans fatty-acid-CoA ligase FadD11 Luciferin 4-monooxygenase   550 aa 498 aa 23.5 %
Leishmania mexicana acetyl-CoA synthetase, putative Luciferin 4-monooxygenase   550 aa 559 aa 20.6 %
Theileria parva long-chain fatty acid CoA ligase, putative Luciferin 4-monooxygenase   550 aa 507 aa 23.5 %
Brugia malayi AMP-binding enzyme family protein Luciferin 4-monooxygenase   550 aa 497 aa 24.7 %
Echinococcus granulosus long chain fatty acid coenzyme A ligase 5 Luciferin 4-monooxygenase   550 aa 458 aa 25.8 %
Candida albicans similar to S. cerevisiae ACS2 (YLR153C) acetyl-CoA synthetase Luciferin 4-monooxygenase   550 aa 539 aa 22.1 %
Mycobacterium leprae Probable fatty-acid-CoA synthetase FadD22 (fatty-acid-CoA ligase) (fatty-acid-CoA synthase) Luciferin 4-monooxygenase   550 aa 493 aa 20.7 %
Echinococcus multilocularis long chain fatty acid coenzyme A ligase 1 Luciferin 4-monooxygenase   550 aa 459 aa 27.0 %
Echinococcus multilocularis long chain fatty acid coenzyme A ligase 5 Luciferin 4-monooxygenase   550 aa 458 aa 25.5 %
Schistosoma mansoni FAA1 Long-chain-fatty-acid--CoA ligase 1 Luciferin 4-monooxygenase   550 aa 494 aa 26.3 %
Dictyostelium discoideum hypothetical protein Luciferin 4-monooxygenase   550 aa 541 aa 21.6 %
Trichomonas vaginalis AMP dependent CoA ligase, putative Luciferin 4-monooxygenase   550 aa 527 aa 25.0 %
Mycobacterium ulcerans peptide synthetase Nrp (peptide synthase) Luciferin 4-monooxygenase   550 aa 535 aa 23.2 %
Onchocerca volvulus Matrilysin homolog Luciferin 4-monooxygenase   550 aa 466 aa 24.2 %
Trichomonas vaginalis antibiotic synthetase, putative Luciferin 4-monooxygenase   550 aa 577 aa 22.2 %
Toxoplasma gondii type I fatty acid synthase, putative Luciferin 4-monooxygenase   550 aa 514 aa 19.8 %
Candida albicans similar to S. cerevisiae FAA4 (YMR246W) long-chain fatty acid--CoA synthetase Luciferin 4-monooxygenase   550 aa 478 aa 23.4 %
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD8 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) Luciferin 4-monooxygenase   550 aa 505 aa 28.1 %
Leishmania infantum long chain fatty Acyl CoA synthetase, putative Luciferin 4-monooxygenase   550 aa 500 aa 23.4 %
Trichomonas vaginalis AMP dependent ligase/synthetase, putative Luciferin 4-monooxygenase   550 aa 494 aa 24.3 %
Mycobacterium tuberculosis Hypothetical protein Nonstructural protein 1   230 aa 202 aa 23.8 %
Dictyostelium discoideum hypothetical protein Luciferin 4-monooxygenase   550 aa 541 aa 21.4 %
Entamoeba histolytica acyl-CoA synthetase, putative Luciferin 4-monooxygenase   550 aa 446 aa 22.0 %
Plasmodium falciparum ras-related protein Rab-5B RAB9A, member RAS oncogene family 201 aa 165 aa 30.9 %
Mycobacterium ulcerans fatty-acid-CoA ligase FadD9 Luciferin 4-monooxygenase   550 aa 463 aa 21.8 %
Dictyostelium discoideum AMP-dependent synthetase and ligase domain-containing protein Luciferin 4-monooxygenase   550 aa 545 aa 24.9 %
Entamoeba histolytica long-chain-fatty-acid--CoA ligase, putative Luciferin 4-monooxygenase   550 aa 476 aa 20.8 %
Onchocerca volvulus Luciferin 4-monooxygenase   550 aa 487 aa 23.8 %
Echinococcus granulosus long chain fatty acid transport protein 4 Luciferin 4-monooxygenase   550 aa 476 aa 22.3 %
Candida albicans similar to S. cerevisiae ACS2 (YLR153C) acetyl-CoA synthetase Luciferin 4-monooxygenase   550 aa 539 aa 22.1 %
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD34 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) Luciferin 4-monooxygenase   550 aa 537 aa 20.9 %
Dictyostelium discoideum AMP-dependent synthetase and ligase domain-containing protein Luciferin 4-monooxygenase   550 aa 550 aa 20.9 %
Mycobacterium leprae Probable fatty-acid-CoA synthetase FadD28 (fatty-acid-CoA ligase) (fatty-acid-CoA synthase) Luciferin 4-monooxygenase   550 aa 484 aa 20.5 %
Mycobacterium tuberculosis Probable acyl-CoA ligase FadD31 (acyl-CoA synthetase) (acyl-CoA synthase) Luciferin 4-monooxygenase   550 aa 592 aa 20.4 %
Candida albicans similar to S. cerevisiae FAT1 (YBR041W) fatty acid transporter and very long-chain fatty acyl-CoA synthetase Luciferin 4-monooxygenase   550 aa 496 aa 24.2 %
Leishmania braziliensis acetyl-CoA synthetase, putative Luciferin 4-monooxygenase   550 aa 596 aa 21.1 %
Candida albicans similar to S. cerevisiae ACS2 (YLR153C) acetyl-CoA synthetase Luciferin 4-monooxygenase   550 aa 543 aa 24.5 %
Trypanosoma cruzi fatty acyl CoA synthetase, putative Luciferin 4-monooxygenase   550 aa 482 aa 24.7 %
Babesia bovis long-chain acyl-CoA synthetase, putative Luciferin 4-monooxygenase   550 aa 445 aa 21.8 %
Dictyostelium discoideum hypothetical protein Luciferin 4-monooxygenase   550 aa 542 aa 22.1 %
Mycobacterium ulcerans long-chain-fatty-acid-CoA ligase FadD15 Luciferin 4-monooxygenase   550 aa 482 aa 24.3 %
Mycobacterium tuberculosis P-hydroxybenzoyl-AMP ligase FadD22 Luciferin 4-monooxygenase   550 aa 493 aa 22.1 %
Trichomonas vaginalis AMP dependent ligase/synthetase, putative Luciferin 4-monooxygenase   550 aa 476 aa 23.5 %
Mycobacterium leprae Probable fatty-acid-CoA synthetase FadD32 (fatty-acid-CoA ligase) (fatty-acid-CoA synthase) Luciferin 4-monooxygenase   550 aa 442 aa 23.5 %
Mycobacterium ulcerans acyl-CoA synthetase Luciferin 4-monooxygenase   550 aa 530 aa 23.8 %
Brugia malayi AMP-binding enzyme family protein Luciferin 4-monooxygenase   550 aa 544 aa 21.5 %
Mycobacterium leprae Probable fatty-acid-CoA synthetase FadD29 (fatty-acid-CoA ligase) (fatty-acid-CoA synthase) Luciferin 4-monooxygenase   550 aa 529 aa 22.3 %
Echinococcus multilocularis long chain fatty acid transport protein 4 Luciferin 4-monooxygenase   550 aa 476 aa 22.3 %
Schistosoma japonicum ko:K08745 solute carrier family 27 (fatty acid transporter), member 1, putative Luciferin 4-monooxygenase   550 aa 501 aa 24.6 %
Schistosoma japonicum ko:K01897 long-chain fatty-acid-CoA ligase [EC6.2.1.3], putative Luciferin 4-monooxygenase   550 aa 466 aa 27.3 %
Dictyostelium discoideum hypothetical protein Luciferin 4-monooxygenase   550 aa 576 aa 19.8 %
Trichomonas vaginalis long-chain-fatty-acid CoA ligase, putative Luciferin 4-monooxygenase   550 aa 490 aa 23.3 %
Candida albicans similar to S. cerevisiae ACS2 (YLR153C) acetyl-CoA synthetase Luciferin 4-monooxygenase   550 aa 543 aa 24.5 %
Mycobacterium tuberculosis Probable peptide synthetase Nrp (peptide synthase) Luciferin 4-monooxygenase   550 aa 509 aa 22.6 %
Toxoplasma gondii propionate-CoA ligase Luciferin 4-monooxygenase   550 aa 550 aa 21.1 %
Dictyostelium discoideum hypothetical protein Luciferin 4-monooxygenase   550 aa 522 aa 19.9 %
Echinococcus granulosus long chain fatty acid coenzyme A ligase 1 Luciferin 4-monooxygenase   550 aa 452 aa 26.1 %
Toxoplasma gondii intraflagellar transport protein 172, putative glycoprotein hormones, alpha polypeptide 116 aa 94 aa 26.6 %
Dictyostelium discoideum AMP-dependent synthetase and ligase domain-containing protein Luciferin 4-monooxygenase   550 aa 531 aa 19.0 %
Trichomonas vaginalis AMP dependent CoA ligase, putative Luciferin 4-monooxygenase   550 aa 492 aa 23.6 %
Mycobacterium tuberculosis Fatty-acid-AMP ligase FadD29 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) Luciferin 4-monooxygenase   550 aa 617 aa 22.2 %
Leishmania braziliensis long chain fatty Acyl CoA synthetase, putative Luciferin 4-monooxygenase   550 aa 496 aa 22.8 %
Mycobacterium ulcerans long-chain-fatty-acid--CoA ligase Luciferin 4-monooxygenase   550 aa 509 aa 21.8 %
Dictyostelium discoideum hypothetical protein Luciferin 4-monooxygenase   550 aa 558 aa 20.4 %
Mycobacterium ulcerans non-ribosomal peptide synthetase MbtE Luciferin 4-monooxygenase   550 aa 502 aa 22.5 %
Echinococcus multilocularis long chain fatty acid coenzyme A ligase 1 Luciferin 4-monooxygenase   550 aa 443 aa 26.4 %
Dictyostelium discoideum hypothetical protein Luciferin 4-monooxygenase   550 aa 507 aa 20.9 %
Trypanosoma brucei gambiense fatty acyl CoA synthetase 4, putative Luciferin 4-monooxygenase   550 aa 497 aa 23.7 %
Onchocerca volvulus Lysine-specific histone demethylase 1A homolog Luciferin 4-monooxygenase   550 aa 550 aa 22.5 %
Mycobacterium ulcerans putative fatty-acid--CoA ligase Luciferin 4-monooxygenase   550 aa 576 aa 20.8 %
Loa Loa (eye worm) AMP-binding enzyme family protein Luciferin 4-monooxygenase   550 aa 489 aa 23.3 %
Trichomonas vaginalis AMP dependent ligase, putative Luciferin 4-monooxygenase   550 aa 445 aa 26.1 %
Dictyostelium discoideum hypothetical protein Luciferin 4-monooxygenase   550 aa 542 aa 18.3 %
Mycobacterium ulcerans long-chain-fatty-acid-CoA ligase FadD15 Luciferin 4-monooxygenase   550 aa 484 aa 26.0 %
Dictyostelium discoideum hypothetical protein Luciferin 4-monooxygenase   550 aa 535 aa 21.7 %
Dictyostelium discoideum hypothetical protein Luciferin 4-monooxygenase   550 aa 535 aa 22.6 %
Loa Loa (eye worm) pigment dispersing factor receptor c glucagon-like peptide 1 receptor 463 aa 388 aa 25.8 %
Dictyostelium discoideum fatty acyl-CoA synthetase Luciferin 4-monooxygenase   550 aa 501 aa 24.4 %
Mycobacterium tuberculosis Fatty-acid-AMP ligase FadD26 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) Luciferin 4-monooxygenase   550 aa 560 aa 21.4 %
Mycobacterium tuberculosis Bifunctional enzyme MbtA: salicyl-AMP ligase (SAL-AMP ligase) + salicyl-S-ArCP synthetase Luciferin 4-monooxygenase   550 aa 536 aa 24.4 %
Leishmania braziliensis acetyl-CoA synthetase, putative Luciferin 4-monooxygenase   550 aa 603 aa 22.6 %
Dictyostelium discoideum fatty acyl-CoA synthetase Luciferin 4-monooxygenase   550 aa 462 aa 23.8 %
Cryptosporidium parvum acyl-CoA synthetase Luciferin 4-monooxygenase   550 aa 460 aa 25.7 %
Trypanosoma cruzi fatty acyl CoA synthetase 2, putative Luciferin 4-monooxygenase   550 aa 495 aa 22.6 %
Dictyostelium discoideum hypothetical protein Luciferin 4-monooxygenase   550 aa 541 aa 21.6 %
Mycobacterium ulcerans acyl-CoA synthetase Luciferin 4-monooxygenase   550 aa 497 aa 19.3 %
Dictyostelium discoideum hypothetical protein Luciferin 4-monooxygenase   550 aa 539 aa 19.1 %
Mycobacterium ulcerans non-ribosomal peptide synthetase MbtF Luciferin 4-monooxygenase   550 aa 558 aa 20.1 %
Trichomonas vaginalis long-chain-fatty-acid CoA ligase, putative Luciferin 4-monooxygenase   550 aa 466 aa 21.7 %
Mycobacterium ulcerans acyl-CoA synthetase Luciferin 4-monooxygenase   550 aa 601 aa 22.5 %
Dictyostelium discoideum hypothetical protein Luciferin 4-monooxygenase   550 aa 463 aa 23.5 %
Mycobacterium leprae Probable fatty-acid-CoA ligase FadD9 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) Luciferin 4-monooxygenase   550 aa 461 aa 22.3 %
Mycobacterium tuberculosis Fatty-acid-AMP ligase FadD32 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase). Also shown to have acyl-ACP ligase activity. Luciferin 4-monooxygenase   550 aa 487 aa 22.4 %
Cryptosporidium parvum putative long chain fatty acyl CoA synthetase having a signal peptide Luciferin 4-monooxygenase   550 aa 472 aa 24.8 %
Entamoeba histolytica long-chain-fatty-acid--CoA ligase, putative Luciferin 4-monooxygenase   550 aa 480 aa 21.5 %
Dictyostelium discoideum hypothetical protein Luciferin 4-monooxygenase   550 aa 539 aa 19.1 %
Mycobacterium tuberculosis Probable fatty-acid-AMP ligase FadD25 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) Luciferin 4-monooxygenase   550 aa 475 aa 21.1 %
Dictyostelium discoideum hypothetical protein Luciferin 4-monooxygenase   550 aa 522 aa 19.9 %
Dictyostelium discoideum hypothetical protein Luciferin 4-monooxygenase   550 aa 541 aa 21.4 %
Mycobacterium leprae Probable long-chain-fatty-acid-CoA ligase FadD15 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) Luciferin 4-monooxygenase   550 aa 484 aa 23.3 %
Dictyostelium discoideum hypothetical protein Luciferin 4-monooxygenase   550 aa 538 aa 21.8 %
Mycobacterium tuberculosis Probable fatty-acid-AMP ligase FadD24 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) Luciferin 4-monooxygenase   550 aa 526 aa 21.9 %
Trichomonas vaginalis AMP dependent ligase/synthetase, putative Luciferin 4-monooxygenase   550 aa 554 aa 22.9 %
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Loa Loa (eye worm) TK protein kinase 0.0052 0.0097 0.0097
Brugia malayi Adenylate and Guanylate cyclase catalytic domain containing protein 0.0052 0.0097 0.0095
Echinococcus granulosus retinal guanylyl cyclase 2 0.0052 0.0097 0.0114
Schistosoma mansoni rhogef and pleckstrin domain protein 0.0048 0.0083 0.0081
Echinococcus granulosus pdz domain containing protein 0.0048 0.0083 0.0097
Brugia malayi Protein kinase domain containing protein 0.0052 0.0097 0.0095
Schistosoma mansoni serine/threonine protein kinase 0.0052 0.0097 0.0095
Giardia lamblia Aurora kinase 0.0072 0.016 1
Brugia malayi plexin A 0.0938 0.2871 0.287
Schistosoma mansoni proto-oncogene tyrosine-protein kinase src 0.0052 0.0097 0.0095
Trichomonas vaginalis Clan MA, family M8, leishmanolysin-like metallopeptidase 0.0147 0.0394 0.2512
Brugia malayi hypothetical protein 0.0052 0.0097 0.0095
Plasmodium falciparum calcium-dependent protein kinase 7 0.0061 0.0124 0.7733
Echinococcus granulosus tyrosine kinase 0.0052 0.0097 0.0114
Schistosoma mansoni protein kinase 0.0065 0.0138 0.0136
Echinococcus granulosus pleckstrin y domain containing family A 0.0048 0.0083 0.0097
Trichomonas vaginalis TKL family protein kinase 0.0052 0.0097 0.061
Echinococcus multilocularis tyrosine protein kinase Blk 0.0052 0.0097 0.0114
Entamoeba histolytica protein kinase, putative 0.0052 0.0097 0.061
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0052 0.0097 0.061
Schistosoma mansoni serine/threonine protein kinase 0.3215 1 1
Trichomonas vaginalis TKL family protein kinase 0.0052 0.0097 0.061
Echinococcus multilocularis dual specificity testis specific protein kinase 0.0065 0.0138 0.0163
Loa Loa (eye worm) hypothetical protein 0.0115 0.0294 0.0294
Brugia malayi hypothetical protein 0.012 0.0309 0.0308
Entamoeba histolytica tyrosin kinase, putative 0.0052 0.0097 0.061
Schistosoma mansoni axis inhibition protein axin 0.0521 0.1565 0.1564
Loa Loa (eye worm) hypothetical protein 0.0052 0.0097 0.0097
Loa Loa (eye worm) hypothetical protein 0.0048 0.0083 0.0083
Schistosoma mansoni serine/threonine RGC 0.0052 0.0097 0.0095
Schistosoma mansoni tyrosine kinase 0.0052 0.0097 0.0095
Onchocerca volvulus Abnormal cell migration protein 10 homolog 0.0048 0.0083 0.0261
Onchocerca volvulus 0.0052 0.0097 0.032
Trichomonas vaginalis TKL family protein kinase 0.0052 0.0097 0.061
Brugia malayi Protein kinase domain containing protein 0.0052 0.0097 0.0095
Entamoeba histolytica protein kinase, putative 0.0052 0.0097 0.061
Trypanosoma cruzi Serine/threonine-protein kinase NEK17, putative 0.0061 0.0124 0.7713
Trypanosoma cruzi PH domain containing protein, putative 0.0048 0.0083 0.5138
Plasmodium falciparum protein kinase, putative 0.0065 0.0138 0.8615
Loa Loa (eye worm) hypothetical protein 0.0521 0.1565 0.1565
Schistosoma mansoni plexin 0.0455 0.1358 0.1356
Entamoeba histolytica serine/threonine- protein kinase 6 , putative 0.0072 0.016 0.1013
Brugia malayi hypothetical protein 0.0052 0.0097 0.0095
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.006 0.0122 0.012
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0052 0.0097 0.061
Entamoeba histolytica pleckstrin homology (PH) domain containing protein 0.0048 0.0083 0.052
Trypanosoma cruzi serine/threonine protein kinase, putative 0.0061 0.0124 0.7713
Trypanosoma cruzi hypothetical protein 0.0048 0.0083 0.5138
Schistosoma mansoni hypothetical protein 0.0455 0.1358 0.1356
Entamoeba histolytica hypothetical protein, conserved domain containing 0.0048 0.0083 0.052
Echinococcus multilocularis epidermal growth factor receptor 0.0052 0.0097 0.0114
Trichomonas vaginalis conserved hypothetical protein 0.0048 0.0083 0.052
Trichomonas vaginalis conserved hypothetical protein 0.0048 0.0083 0.052
Leishmania major 4-coumarate:coa ligase-like protein 0.0029 0.0023 0.1342
Schistosoma mansoni hypothetical protein 0.0028 0.0021 0.0019
Trichomonas vaginalis TKL family protein kinase 0.0052 0.0097 0.061
Schistosoma mansoni ephrin receptor 0.0057 0.0112 0.0111
Mycobacterium ulcerans long-chain-fatty-acid--CoA ligase 0.0029 0.0023 1
Echinococcus granulosus epidermal growth factor receptor 0.0052 0.0097 0.0114
Echinococcus granulosus macrophage colony stimulating factor 1 receptor 0.0052 0.0097 0.0114
Leishmania major phosphatidylinositol kinase related protein, putative 0.0022 0.0002 0.0008
Brugia malayi Oxysterol binding protein 0.0048 0.0083 0.0081
Echinococcus multilocularis heat shock protein 70 0.0052 0.0097 0.0114
Onchocerca volvulus outspread protein homolog 0.0048 0.0083 0.0261
Trichomonas vaginalis TKL family protein kinase 0.0052 0.0097 0.061
Trypanosoma cruzi hypothetical protein 0.0048 0.0083 0.5138
Onchocerca volvulus 0.0048 0.0083 0.0261
Echinococcus granulosus protein tyrosine kinase 0.0052 0.0097 0.0114
Schistosoma mansoni centaurin alpha 0.0048 0.0083 0.0081
Trichomonas vaginalis AGC family protein kinase 0.0061 0.0124 0.0781
Trypanosoma brucei aurora B kinase 0.0072 0.016 1
Trichomonas vaginalis TKL family protein kinase 0.0052 0.0097 0.061
Brugia malayi Sema domain containing protein 0.0336 0.0986 0.0984
Trichomonas vaginalis AGC family protein kinase 0.0061 0.0124 0.0781
Onchocerca volvulus 0.0052 0.0097 0.032
Entamoeba histolytica tyrosine kinase, putative 0.0052 0.0097 0.061
Echinococcus multilocularis potassium voltage gated channel subfamily H 0.0039 0.0055 0.0064
Loa Loa (eye worm) hypothetical protein 0.012 0.0309 0.0309
Brugia malayi Receptor family ligand binding region containing protein 0.0052 0.0097 0.0095
Trypanosoma brucei NEK family Serine/threonine-protein kinase, putative 0.0061 0.0124 0.7713
Plasmodium vivax conserved Plasmodium protein, unknown function 0.0048 0.0083 0.518
Brugia malayi Protein kinase domain containing protein 0.0052 0.0097 0.0095
Echinococcus granulosus plexin a4 0.0938 0.2871 0.343
Entamoeba histolytica hypothetical protein 0.0043 0.0069 0.0433
Schistosoma mansoni hypothetical protein 0.0048 0.0083 0.0081
Echinococcus granulosus Pleckstrin y 0.0048 0.0083 0.0097
Plasmodium vivax calcium-dependent protein kinase 7, putative 0.0061 0.0124 0.7733
Trypanosoma cruzi rac serine-threonine kinase, putative 0.0061 0.0124 0.7713
Loa Loa (eye worm) hypothetical protein 0.0791 0.241 0.241
Brugia malayi Calcitonin receptor-like protein seb-1 0.006 0.0122 0.012
Trichomonas vaginalis conserved hypothetical protein 0.0521 0.1565 1
Trichomonas vaginalis AGC family protein kinase 0.0061 0.0124 0.0781
Brugia malayi Protein kinase domain containing protein 0.0052 0.0097 0.0095
Schistosoma mansoni ephrin receptor 0.0052 0.0097 0.0095
Loa Loa (eye worm) oxysterol binding protein 0.0048 0.0083 0.0083
Loa Loa (eye worm) TK protein kinase 0.0052 0.0097 0.0097
Trichomonas vaginalis TKL family protein kinase 0.0052 0.0097 0.061
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.003 0.0027 0.0026
Echinococcus granulosus fibroblast growth factor receptor 4 0.0052 0.0097 0.0114
Echinococcus multilocularis tyrosine protein kinase lyn tyrosine protein kinase blk 0.0052 0.0097 0.0114
Loa Loa (eye worm) TK/FER protein kinase 0.0052 0.0097 0.0097
Echinococcus multilocularis atpase aaa+ type core atpase aaa type core 0.0979 0.2999 0.3583
Echinococcus granulosus regulator of G protein signaling 3 0.0521 0.1565 0.1869
Trypanosoma brucei serine/threonine-protein kinase NrkA 0.0061 0.0124 0.7713
Loa Loa (eye worm) TK/FER protein kinase 0.0052 0.0097 0.0097
Schistosoma mansoni hypothetical protein 0.0336 0.0986 0.0984
Trichomonas vaginalis TKL family protein kinase 0.0052 0.0097 0.061
Trichomonas vaginalis conserved hypothetical protein 0.0048 0.0083 0.052
Trypanosoma cruzi phosphatidylinositol kinase related protein, putative 0.003 0.0027 0.1613
Echinococcus multilocularis sterol regulatory element binding protein 0.0051 0.0093 0.0109
Brugia malayi Sema domain containing protein 0.0336 0.0986 0.0984
Entamoeba histolytica hypothetical protein 0.0048 0.0083 0.052
Trichomonas vaginalis ankyrin repeat-containing protein, putative 0.0048 0.0083 0.052
Schistosoma mansoni protein kinase 0.0065 0.0138 0.0136
Entamoeba histolytica ARF GTPase activating protein, putative 0.0048 0.0083 0.052
Schistosoma mansoni transcription factor LCR-F1 0.0043 0.0069 0.0068
Entamoeba histolytica PH domain containing protein kinase, putative 0.0061 0.0124 0.0781
Schistosoma mansoni vav2 0.0048 0.0083 0.0081
Echinococcus multilocularis tyrosine kinase 0.0052 0.0097 0.0114
Brugia malayi TBC domain containing protein 0.0048 0.0083 0.0081
Entamoeba histolytica tyrosine kinase, putative 0.0052 0.0097 0.061
Loa Loa (eye worm) AUR protein kinase 0.0072 0.016 0.016
Trypanosoma cruzi phosphatidylinositol kinase related protein, putative 0.0026 0.0014 0.0782
Echinococcus granulosus myotubularin protein 13 0.0048 0.0083 0.0097
Trypanosoma brucei Serine/threonine-protein kinase NEK21, putative 0.0061 0.0124 0.7713
Echinococcus granulosus arf GAP with SH3 domain ANK repeat and PH 0.0048 0.0083 0.0097
Trichomonas vaginalis conserved hypothetical protein 0.0048 0.0083 0.052
Schistosoma mansoni tyrosine kinase 0.0052 0.0097 0.0095
Schistosoma mansoni hypothetical protein 0.0043 0.0069 0.0068
Trichomonas vaginalis protein transport protein sec7, putative 0.0048 0.0083 0.052
Plasmodium falciparum protein kinase, putative 0.0052 0.0097 0.6063
Schistosoma mansoni hypothetical protein 0.0336 0.0986 0.0984
Entamoeba histolytica hypothetical protein 0.0061 0.0124 0.0781
Echinococcus multilocularis tyrosine protein kinase Srms 0.0052 0.0097 0.0114
Entamoeba histolytica hypothetical protein, conserved domain containing 0.0048 0.0083 0.052
Loa Loa (eye worm) TK/ABL protein kinase 0.0052 0.0097 0.0097
Echinococcus granulosus tyrosine protein kinase csk 0.0052 0.0097 0.0114
Echinococcus multilocularis FL cytokine receptor 0.0052 0.0097 0.0114
Plasmodium vivax tyrosine kinase-like protein, putative 0.0052 0.0097 0.6063
Entamoeba histolytica protein kinase, putative 0.0052 0.0097 0.061
Loa Loa (eye worm) hypothetical protein 0.0026 0.0014 0.0014
Echinococcus granulosus type II inositol 34 bisphosphate 4 phosphatase 0.0048 0.0083 0.0097
Entamoeba histolytica protein kinase, putative 0.0052 0.0097 0.061
Echinococcus granulosus tyrosine protein kinase HCK 0.0052 0.0097 0.0114
Schistosoma mansoni hypothetical protein 0.0049 0.0087 0.0086
Brugia malayi Furin-like cysteine rich region family protein 0.0052 0.0097 0.0095
Echinococcus multilocularis FERM and pleckstrin domain containing protein 0.0048 0.0083 0.0097
Trypanosoma cruzi hypothetical protein 0.0048 0.0083 0.5138
Echinococcus granulosus Rho GTPase activating protein 24 0.0048 0.0083 0.0097
Entamoeba histolytica protein kinase domain containing protein 0.0052 0.0097 0.061
Loa Loa (eye worm) TK/FER protein kinase 0.0052 0.0097 0.0097
Trichomonas vaginalis TKL family protein kinase 0.0052 0.0097 0.061
Schistosoma mansoni protein kinase 0.0052 0.0097 0.0095
Loa Loa (eye worm) serine/threonine protein kinase 0.0052 0.0097 0.0097
Plasmodium falciparum tyrosine kinase-like protein 0.0052 0.0097 0.6063
Brugia malayi Protein kinase domain containing protein 0.0052 0.0097 0.0095
Brugia malayi Regulator of G protein signaling domain containing protein 0.0521 0.1565 0.1564
Entamoeba histolytica hypothetical protein 0.0052 0.0097 0.061
Brugia malayi integrin-linked kinase 0.0052 0.0097 0.0095
Echinococcus multilocularis expressed protein 0.0521 0.1565 0.1869
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0052 0.0097 0.061
Onchocerca volvulus Protein melted homolog 0.0048 0.0083 0.0261
Entamoeba histolytica receptor protein kinase, putative 0.0052 0.0097 0.061
Schistosoma mansoni syntrophin 0.0048 0.0083 0.0081
Brugia malayi Protein kinase domain containing protein 0.0052 0.0097 0.0095
Entamoeba histolytica protein kinase, putative 0.0052 0.0097 0.061
Entamoeba histolytica tyrosin kinase, putative 0.0052 0.0097 0.061
Loa Loa (eye worm) TK protein kinase 0.0052 0.0097 0.0097
Brugia malayi Protein kinase domain containing protein 0.0052 0.0097 0.0095
Trichomonas vaginalis TKL family protein kinase 0.0052 0.0097 0.061
Echinococcus multilocularis tyrosine protein kinase HCK 0.0052 0.0097 0.0114
Echinococcus granulosus sterol regulatory element binding protein 0.0051 0.0093 0.0109
Entamoeba histolytica hypothetical protein, conserved domain containing 0.0048 0.0083 0.052
Trichomonas vaginalis AGC family protein kinase 0.0061 0.0124 0.0781
Echinococcus multilocularis expressed conserved protein 0.0112 0.0283 0.0336
Schistosoma mansoni semaphorin 5-related 0.0336 0.0986 0.0984
Echinococcus multilocularis axis inhibition protein axin 0.0521 0.1565 0.1869
Echinococcus granulosus Pleckstrin y 0.0048 0.0083 0.0097
Echinococcus granulosus 3'partial|tyrosine protein kinase Fgr 0.0052 0.0097 0.0114
Echinococcus multilocularis tyrosine protein kinase ABL1 0.0052 0.0097 0.0114
Schistosoma mansoni tyrosine kinase 0.0052 0.0097 0.0095
Entamoeba histolytica protein kinase, putative 0.0052 0.0097 0.061
Leishmania major protein kinase, putative 0.0072 0.016 1
Echinococcus granulosus expressed protein 0.0521 0.1565 0.1869
Trichomonas vaginalis TKL family protein kinase 0.0052 0.0097 0.061
Onchocerca volvulus Putative neuronal RhoA GEF protein 0.0048 0.0083 0.0261
Brugia malayi serine/threonine-protein kinase 6 0.0072 0.016 0.0158
Trichomonas vaginalis ankyrin repeat-containing protein, putative 0.0048 0.0083 0.052
Trichomonas vaginalis conserved hypothetical protein 0.0048 0.0083 0.052
Echinococcus granulosus Arf GAP and Pleckstrin domain containing protein 0.0048 0.0083 0.0097
Loa Loa (eye worm) TK/FER protein kinase 0.0052 0.0097 0.0097
Echinococcus granulosus tyrosine protein kinase Src64B 0.0052 0.0097 0.0114
Trichomonas vaginalis Clan MA, family M8, leishmanolysin-like metallopeptidase 0.0147 0.0394 0.2512
Trypanosoma cruzi hypothetical protein 0.0048 0.0083 0.5138
Echinococcus multilocularis Rho GTPase activating protein 24 0.0048 0.0083 0.0097
Brugia malayi Probable G protein-coupled receptor kinase F19C6.1, putative 0.2694 0.8368 0.8368
Schistosoma mansoni regulator of G protein signaling 3 rgs3 0.0521 0.1565 0.1564
Loa Loa (eye worm) TK/FER protein kinase 0.0052 0.0097 0.0097
Brugia malayi latrophilin 2 splice variant baaae 0.0041 0.0062 0.006
Schistosoma mansoni serine/threonine-protein kinase 0.0061 0.0124 0.0122
Brugia malayi Variant SH3 domain containing protein 0.0048 0.0083 0.0081
Echinococcus multilocularis basic fibroblast growth factor receptor 1 A 0.0052 0.0097 0.0114
Brugia malayi Cytohesin 3 0.0048 0.0083 0.0081
Echinococcus granulosus semaphorin 5B 0.0336 0.0986 0.1176
Entamoeba histolytica PH domain containing protein kinase, putative 0.0061 0.0124 0.0781
Loa Loa (eye worm) hypothetical protein 0.0048 0.0083 0.0083
Entamoeba histolytica protein kinase domain containing protein 0.0052 0.0097 0.061
Entamoeba histolytica hypothetical protein 0.0147 0.0394 0.2512
Leishmania major protein kinase, putative 0.0052 0.0097 0.6028
Trichomonas vaginalis conserved hypothetical protein 0.0052 0.0097 0.061
Loa Loa (eye worm) TK/ACK protein kinase 0.0052 0.0097 0.0097
Echinococcus multilocularis tyrosine protein kinase csk 0.0052 0.0097 0.0114
Loa Loa (eye worm) hypothetical protein 0.0336 0.0986 0.0986
Trichomonas vaginalis TKL family protein kinase 0.0052 0.0097 0.061
Schistosoma mansoni guanyl-nucleotide exchange factor 0.0048 0.0083 0.0081
Brugia malayi SH2 domain containing protein 0.0052 0.0097 0.0095
Echinococcus granulosus aurora kinase A 0.0072 0.016 0.0189
Echinococcus granulosus epidermal growth factor receptor 0.0052 0.0097 0.0114
Echinococcus granulosus transcription factor collier 0.0147 0.0394 0.0469
Entamoeba histolytica protein kinase , putative 0.0072 0.016 0.1013
Schistosoma mansoni regulator of G protein signaling 0.0521 0.1565 0.1564
Trichomonas vaginalis conserved hypothetical protein 0.0048 0.0083 0.052
Echinococcus multilocularis serine protein kinase ATM 0.003 0.0027 0.0031
Loa Loa (eye worm) plexin A 0.0938 0.2871 0.2871
Schistosoma mansoni tyrosine kinase 0.0052 0.0097 0.0095
Schistosoma mansoni serine/threonine protein kinase 0.2465 0.765 0.7649
Loa Loa (eye worm) hypothetical protein 0.0048 0.0083 0.0083
Schistosoma mansoni protein kinase 0.0052 0.0097 0.0095
Loa Loa (eye worm) TK protein kinase 0.0052 0.0097 0.0097
Leishmania major hypothetical protein, conserved 0.0048 0.0083 0.5138
Brugia malayi PH domain containing protein 0.0048 0.0083 0.0081
Schistosoma mansoni protein kinase 0.0065 0.0138 0.0136
Entamoeba histolytica hypothetical protein 0.0147 0.0394 0.2512
Trichomonas vaginalis protein transport protein sec7, putative 0.0048 0.0083 0.052
Echinococcus granulosus 3'partial|retinal guanylyl cyclase 2 0.0052 0.0097 0.0114
Echinococcus granulosus tyrosine protein kinase Src42A 0.0052 0.0097 0.0114
Schistosoma mansoni tyrosine kinase 0.0052 0.0097 0.0095
Loa Loa (eye worm) hypothetical protein 0.0028 0.0021 0.0021
Trichomonas vaginalis conserved hypothetical protein 0.0048 0.0083 0.052
Trichomonas vaginalis AGC family protein kinase 0.0061 0.0124 0.0781
Loa Loa (eye worm) AGC/GRK/GRK protein kinase 0.3215 1 1
Schistosoma mansoni hypothetical protein 0.0052 0.0097 0.0095
Echinococcus granulosus ras specific guanine nucleotide releasing factor 0.0048 0.0083 0.0097
Loa Loa (eye worm) AGC/GRK/BARK protein kinase 0.2465 0.765 0.765
Loa Loa (eye worm) SRC-1 0.0052 0.0097 0.0097
Schistosoma mansoni tyrosine kinase 0.0052 0.0097 0.0095
Onchocerca volvulus 0.0052 0.0097 0.032
Echinococcus multilocularis Immunoglobulin 0.0115 0.0294 0.035
Trichomonas vaginalis TKL family protein kinase 0.0052 0.0097 0.061
Echinococcus granulosus tyrosine protein kinase Fps85D 0.0052 0.0097 0.0114
Loa Loa (eye worm) protein kinase domain-containing protein 0.0052 0.0097 0.0097
Schistosoma mansoni hypothetical protein 0.0147 0.0394 0.0393
Schistosoma mansoni tyrosine kinase 0.0052 0.0097 0.0095
Trichomonas vaginalis conserved hypothetical protein 0.0048 0.0083 0.052
Echinococcus granulosus tyrosine protein kinase Fyn 0.0052 0.0097 0.0114
Loa Loa (eye worm) hypothetical protein 0.0048 0.0083 0.0083
Trichomonas vaginalis TKL family protein kinase 0.0052 0.0097 0.061
Echinococcus granulosus serine protein kinase ATM 0.003 0.0027 0.0031
Brugia malayi C-terminal src kinase protein 1 0.0052 0.0097 0.0095
Trichomonas vaginalis TKL family protein kinase 0.0052 0.0097 0.061
Loa Loa (eye worm) TK/Met protein kinase 0.0052 0.0097 0.0097
Loa Loa (eye worm) hypothetical protein 0.0052 0.0097 0.0097
Trichomonas vaginalis TKL family protein kinase 0.0052 0.0097 0.061
Echinococcus multilocularis tyrosine protein kinase csk 0.0052 0.0097 0.0114
Entamoeba histolytica PH domain containing protein kinase, putative 0.0061 0.0124 0.0781
Echinococcus multilocularis MAM 0.0028 0.0021 0.0023
Echinococcus granulosus receptor type guanylyl cyclase 0.0052 0.0097 0.0114
Entamoeba histolytica serine/threonine kinase, putative 0.0052 0.0097 0.061
Entamoeba histolytica hypothetical protein, conserved 0.0048 0.0083 0.052
Echinococcus granulosus arf GAP with coiled coil ANK repeat and PH 0.0048 0.0083 0.0097
Loa Loa (eye worm) TKL/RAF/KSR protein kinase 0.0052 0.0097 0.0097
Trichomonas vaginalis AGC family protein kinase 0.0072 0.016 0.1013
Trichomonas vaginalis AGC family protein kinase 0.0061 0.0124 0.0781
Trichomonas vaginalis ankyrin repeat and FYVE domain containing protein, putative 0.0048 0.0083 0.052
Echinococcus granulosus retinal guanylyl cyclase 2 0.0052 0.0097 0.0114
Schistosoma mansoni regulator of G protein signaling 17 19 20 (rgs17 19 20) 0.0521 0.1565 0.1564
Schistosoma mansoni tyrosine kinase 0.0052 0.0097 0.0095
Echinococcus granulosus activated cdc42 kinase 1 0.0052 0.0097 0.0114
Trichomonas vaginalis AGC family protein kinase 0.0061 0.0124 0.0781
Onchocerca volvulus 0.0048 0.0083 0.0261
Entamoeba histolytica hypothetical protein 0.0052 0.0097 0.061
Trichomonas vaginalis TKL family protein kinase 0.0052 0.0097 0.061
Schistosoma mansoni patched 1 0.0051 0.0093 0.0091
Entamoeba histolytica protein kinase domain containing protein 0.0072 0.016 0.1013
Echinococcus granulosus FERM and pleckstrin domain containing protein 0.0048 0.0083 0.0097
Entamoeba histolytica PH domain containing protein kinase, putative 0.0061 0.0124 0.0781
Onchocerca volvulus 0.0052 0.0097 0.032
Echinococcus multilocularis tyrosine protein kinase pr2 0.0052 0.0097 0.0114
Loa Loa (eye worm) AUR protein kinase 0.0072 0.016 0.016
Loa Loa (eye worm) hypothetical protein 0.0034 0.0039 0.0039
Echinococcus multilocularis integrin linked protein kinase 0.0052 0.0097 0.0114
Schistosoma mansoni tyrosine kinase 0.0052 0.0097 0.0095
Echinococcus granulosus regulator of G protein signaling 7 0.0521 0.1565 0.1869
Schistosoma mansoni rho gtpase activating protein 0.0048 0.0083 0.0081
Brugia malayi Protein kinase domain containing protein 0.0052 0.0097 0.0095
Toxoplasma gondii calcium dependent protein kinase CDPK8 0.0065 0.0138 0.8603
Loa Loa (eye worm) hypothetical protein 0.0041 0.0062 0.0062
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0052 0.0097 0.061
Trichomonas vaginalis TKL family protein kinase 0.0052 0.0097 0.061
Loa Loa (eye worm) TK protein kinase 0.0052 0.0097 0.0097
Echinococcus granulosus basic fibroblast growth factor receptor 1 A 0.0052 0.0097 0.0114
Entamoeba histolytica hypothetical protein 0.0043 0.0069 0.0433
Echinococcus granulosus calcium dependent secretion activator 1 0.0048 0.0083 0.0097
Trichomonas vaginalis TKL family protein kinase 0.0052 0.0097 0.061
Echinococcus multilocularis tyrosine protein kinase Fps85D 0.0052 0.0097 0.0114
Entamoeba histolytica protein kinase domain containing protein 0.0052 0.0097 0.061
Echinococcus multilocularis receptor type guanylyl cyclase 0.0052 0.0097 0.0114
Brugia malayi hypothetical protein 0.0043 0.0069 0.0068
Plasmodium vivax oxysterol-binding protein/PH domain containing protein 0.0048 0.0083 0.518
Entamoeba histolytica hypothetical protein 0.0043 0.0069 0.0433
Loa Loa (eye worm) variant SH3 domain-containing protein 0.0048 0.0083 0.0083
Trichomonas vaginalis centaurin beta, putative 0.0048 0.0083 0.052
Echinococcus granulosus c src tyrosine kinase 0.0052 0.0097 0.0114
Loa Loa (eye worm) hypothetical protein 0.012 0.0309 0.0309
Schistosoma mansoni tyrosine kinase 0.0052 0.0097 0.0095
Loa Loa (eye worm) hypothetical protein 0.0147 0.0394 0.0394
Entamoeba histolytica protein kinase, putative 0.0052 0.0097 0.061
Echinococcus multilocularis tyrosine protein kinase shark 0.0052 0.0097 0.0114
Entamoeba histolytica ankyrin repeat protein 0.0052 0.0097 0.061
Entamoeba histolytica protein kinase domain containing protein 0.0052 0.0097 0.061
Brugia malayi PH domain containing protein 0.0048 0.0083 0.0081
Entamoeba histolytica hypothetical protein 0.0147 0.0394 0.2512
Schistosoma mansoni tyrosine kinase 0.0052 0.0097 0.0095
Trichomonas vaginalis TKL family protein kinase 0.0052 0.0097 0.061
Mycobacterium ulcerans long-chain-fatty-acid-CoA ligase 0.0029 0.0023 1
Echinococcus multilocularis exocyst complex component 2 0.0147 0.0394 0.0469
Echinococcus granulosus activated cdc42 kinase 1 0.0052 0.0097 0.0114
Trichomonas vaginalis protein kinase atn1, putative 0.0052 0.0097 0.061
Loa Loa (eye worm) hypothetical protein 0.0048 0.0083 0.0083
Toxoplasma gondii AtPH1 family protein 0.0048 0.0083 0.5138
Loa Loa (eye worm) TKL/RAF/RAF protein kinase 0.0052 0.0097 0.0097
Schistosoma mansoni tyrosine protein kinase 0.0052 0.0097 0.0095
Schistosoma mansoni tyrosine kinase 0.0052 0.0097 0.0095
Plasmodium falciparum conserved Plasmodium protein, unknown function 0.0048 0.0083 0.518
Loa Loa (eye worm) hypothetical protein 0.0336 0.0986 0.0986
Schistosoma mansoni zinc finger protein 0.0048 0.0083 0.0081
Schistosoma mansoni regulator of G protein signaling 0.0521 0.1565 0.1564
Trichomonas vaginalis conserved hypothetical protein 0.0147 0.0394 0.2512
Brugia malayi PH domain containing protein 0.0048 0.0083 0.0081
Loa Loa (eye worm) hypothetical protein 0.0115 0.0294 0.0294
Loa Loa (eye worm) TK/FER protein kinase 0.0052 0.0097 0.0097
Loa Loa (eye worm) hypothetical protein 0.0521 0.1565 0.1565
Plasmodium falciparum oxysterol-binding protein, putative 0.0048 0.0083 0.518
Schistosoma mansoni tyrosine kinase 0.0052 0.0097 0.0095
Echinococcus multilocularis insulin growth factor 1 receptor beta 0.0057 0.0112 0.0132
Entamoeba histolytica tyrosine kinase, putative 0.0052 0.0097 0.061
Trypanosoma cruzi phosphatidylinositol-4-phosphate 5-kinase, putative 0.0048 0.0083 0.5138
Brugia malayi Plekhf2 protein 0.0048 0.0083 0.0081
Entamoeba histolytica protein kinase, putative 0.0061 0.0124 0.0781
Trichomonas vaginalis TKL family protein kinase 0.0052 0.0097 0.061
Brugia malayi Dynamin 0.0048 0.0083 0.0081
Schistosoma mansoni hypothetical protein 0.0041 0.0062 0.006
Brugia malayi hypothetical protein 0.0052 0.0097 0.0095
Loa Loa (eye worm) sema domain-containing protein 0.0336 0.0986 0.0986
Echinococcus multilocularis Regulator of G protein signaling 20 0.0521 0.1565 0.1869
Loa Loa (eye worm) AGC/AKT protein kinase 0.0061 0.0124 0.0124
Schistosoma mansoni tyrosine protein kinase fes (fps) (ptk group IV) 0.0052 0.0097 0.0095
Schistosoma mansoni serine/threonine protein kinase 0.2465 0.765 0.7649
Entamoeba histolytica hypothetical protein 0.0052 0.0097 0.061
Plasmodium falciparum tyrosine kinase-like protein 0.0052 0.0097 0.6063
Trichomonas vaginalis conserved hypothetical protein 0.0052 0.0097 0.061
Echinococcus multilocularis regulator of G protein signaling 0.0521 0.1565 0.1869
Toxoplasma gondii Tyrosine kinase-like (TKL) protein 0.0052 0.0097 0.6028
Schistosoma mansoni protein kinase 0.0052 0.0097 0.0095
Trichomonas vaginalis conserved hypothetical protein 0.0048 0.0083 0.052
Trichomonas vaginalis hypothetical protein 0.0048 0.0083 0.052
Echinococcus granulosus kinase suppressor of Ras 1 0.0052 0.0097 0.0114
Loa Loa (eye worm) hypothetical protein 0.0052 0.0097 0.0097
Trypanosoma cruzi protein kinase, putative 0.0052 0.0097 0.6028
Brugia malayi Protein kinase domain containing protein 0.0052 0.0097 0.0095
Trichomonas vaginalis conserved hypothetical protein 0.0048 0.0083 0.052
Trypanosoma cruzi STE/STE11 serine/threonine-protein kinase, putative 0.0065 0.0138 0.8603
Echinococcus granulosus GRB2 associated binding protein 3 0.0048 0.0083 0.0097
Loa Loa (eye worm) phosphatidylinositol 3 0.0022 0.0001 0.0001
Echinococcus granulosus [G-protein-coupledreceptor] kinase 0.2694 0.8368 1
Brugia malayi PH domain containing protein 0.0048 0.0083 0.0081
Loa Loa (eye worm) sema domain-containing protein 0.0336 0.0986 0.0986
Schistosoma mansoni protein kinase 0.0052 0.0097 0.0095
Schistosoma mansoni hypothetical protein 0.0049 0.0087 0.0086
Plasmodium falciparum protein kinase, putative 0.0052 0.0097 0.6063
Echinococcus multilocularis mitogen activated protein kinase kinase kinase 0.0052 0.0097 0.0114
Loa Loa (eye worm) hypothetical protein 0.0147 0.0394 0.0394
Loa Loa (eye worm) GTP-ase activating protein for Arf containing protein 0.0048 0.0083 0.0083
Brugia malayi Protein kinase domain containing protein 0.0052 0.0097 0.0095
Echinococcus multilocularis G protein coupled receptor kinase 6 0.2694 0.8368 1
Onchocerca volvulus 0.0048 0.0083 0.0261
Entamoeba histolytica protein kinase, putative 0.0052 0.0097 0.061
Echinococcus multilocularis beta 1 syntrophin 0.0048 0.0083 0.0097
Echinococcus granulosus Pleckstrin domain containing protein family B 0.0048 0.0083 0.0097
Loa Loa (eye worm) cytohesin 3 0.0048 0.0083 0.0083
Entamoeba histolytica serine/threonine kinase, putative 0.0052 0.0097 0.061
Entamoeba histolytica tyrosine kinase, putative 0.0052 0.0097 0.061
Echinococcus multilocularis insulin receptor 0.0052 0.0097 0.0114
Schistosoma mansoni hypothetical protein 0.0049 0.0087 0.0086
Echinococcus multilocularis tyrosine kinase 0.0052 0.0097 0.0114
Brugia malayi hypothetical protein 0.0048 0.0083 0.0081
Loa Loa (eye worm) TK/FER protein kinase 0.0052 0.0097 0.0097
Echinococcus multilocularis calcium dependent secretion activator 1 0.0048 0.0083 0.0097
Schistosoma mansoni voltage-gated potassium channel 0.0043 0.0066 0.0065
Brugia malayi Raf kinase 0.0052 0.0097 0.0095
Trichomonas vaginalis TKL family protein kinase 0.0052 0.0097 0.061
Loa Loa (eye worm) hypothetical protein 0.0029 0.0023 0.0023
Trypanosoma brucei AGC/RSK family serine/threonine kinase, putative 0.0052 0.0097 0.6028
Loa Loa (eye worm) hypothetical protein 0.0521 0.1565 0.1565
Echinococcus multilocularis Oxysterol binding protein 11 0.0048 0.0083 0.0097
Schistosoma mansoni axis inhibition protein axin 0.0521 0.1565 0.1564
Trichomonas vaginalis ribosomal protein S6 kinase, 90kD, polypeptide, putative 0.0061 0.0124 0.0781
Mycobacterium tuberculosis Probable chain -fatty-acid-CoA ligase FadD13 (fatty-acyl-CoA synthetase) 0.0029 0.0023 1
Brugia malayi SRC-1 0.0052 0.0097 0.0095
Trichomonas vaginalis TKL family protein kinase 0.0052 0.0097 0.061
Trichomonas vaginalis TKL family protein kinase 0.0052 0.0097 0.061
Schistosoma mansoni niemann-pick C1 (NPC1) 0.0121 0.0311 0.031
Brugia malayi Protein kinase domain containing protein 0.0052 0.0097 0.0095
Echinococcus granulosus semaphorin 1A 0.0336 0.0986 0.1176
Trichomonas vaginalis TKL family protein kinase 0.0052 0.0097 0.061
Mycobacterium ulcerans acyl-CoA synthetase 0.0029 0.0023 1
Schistosoma mansoni goodpasture antigen-binding protein 0.0048 0.0083 0.0081
Loa Loa (eye worm) hypothetical protein 0.0048 0.0083 0.0083
Schistosoma mansoni hypothetical protein 0.0028 0.0021 0.0019
Entamoeba histolytica tyrosine kinase, putative 0.0052 0.0097 0.061
Schistosoma mansoni tyrosine kinase 0.0052 0.0097 0.0095
Loa Loa (eye worm) hypothetical protein 0.0048 0.0083 0.0083
Plasmodium falciparum acylated pleckstrin-homology domain-containing protein, putative 0.0048 0.0083 0.518
Loa Loa (eye worm) PH domain-containing protein 0.0048 0.0083 0.0083
Echinococcus multilocularis transfer RNA-Thr 0.0052 0.0097 0.0114
Loa Loa (eye worm) hypothetical protein 0.0119 0.0305 0.0305
Trichomonas vaginalis TKL family protein kinase 0.0052 0.0097 0.061
Schistosoma mansoni protein kinase 0.0072 0.016 0.0158
Trichomonas vaginalis AGC family protein kinase 0.0061 0.0124 0.0781
Entamoeba histolytica PH domain containing protein 0.0048 0.0083 0.052
Brugia malayi Protein kinase domain containing protein 0.0052 0.0097 0.0095
Schistosoma mansoni phosphoinositol 4-phosphate adaptor protein 0.0048 0.0083 0.0081
Loa Loa (eye worm) hypothetical protein 0.0048 0.0083 0.0083
Echinococcus granulosus DCC interacting protein 13 beta 0.0048 0.0083 0.0097
Trichomonas vaginalis TKL family protein kinase 0.0052 0.0097 0.061
Echinococcus multilocularis mitogen activated protein kinase kinase kinase 0.0052 0.0097 0.0114
Schistosoma mansoni protein kinase 0.0052 0.0097 0.0095
Brugia malayi regulator of G-protein signaling egl-10 0.0521 0.1565 0.1564
Loa Loa (eye worm) PXA domain-containing protein 0.0521 0.1565 0.1565
Brugia malayi A-kinase anchor protein 10, precursor 0.0521 0.1565 0.1564
Plasmodium vivax serine/threonine protein kinase 6, putative 0.0072 0.016 1
Echinococcus granulosus Niemann Pick C1 protein 0.017 0.0465 0.0554
Trichomonas vaginalis conserved hypothetical protein 0.0147 0.0394 0.2512
Echinococcus granulosus G protein coupled receptor kinase 1 0.1943 0.6018 0.7191
Echinococcus multilocularis type II inositol 3,4 bisphosphate 4 phosphatase 0.0048 0.0083 0.0097
Onchocerca volvulus 0.0052 0.0097 0.032
Entamoeba histolytica tyrosine kinase, putative 0.0052 0.0097 0.061
Brugia malayi Variant SH3 domain containing protein 0.0048 0.0083 0.0081
Trypanosoma cruzi serine/threonine-protein kinase NRKB, putative 0.0061 0.0124 0.7713
Brugia malayi SH2 domain containing protein 0.0052 0.0097 0.0095
Echinococcus granulosus tyrosine kinase 0.0052 0.0097 0.0114
Entamoeba histolytica cysteine surface protein, putative 0.0052 0.0097 0.061
Brugia malayi Tyrosine-protein kinase PR2 0.0052 0.0097 0.0095
Trichomonas vaginalis guanyl-nucleotide exchange factor, putative 0.0048 0.0083 0.052
Loa Loa (eye worm) hypothetical protein 0.0336 0.0986 0.0986
Onchocerca volvulus Putative zinc finger protein 0.0048 0.0083 0.0261
Echinococcus granulosus tyrosine protein kinase Srms 0.0052 0.0097 0.0114
Echinococcus multilocularis protein KINase family member (kin 25) 0.0052 0.0097 0.0114
Brugia malayi Plexin repeat family protein 0.0791 0.241 0.2409
Echinococcus multilocularis aurora kinase A 0.0072 0.016 0.0189
Trichomonas vaginalis TK family protein kinase 0.0052 0.0097 0.061
Trypanosoma brucei Flagellum attachment zone protein 20 0.0052 0.0097 0.6028
Trichomonas vaginalis TKL family protein kinase 0.0052 0.0097 0.061
Loa Loa (eye worm) TK/KIN16 protein kinase 0.0168 0.0458 0.0458
Echinococcus granulosus mitogen-activated protein kinase kinase kinase 9 0.0052 0.0097 0.0114
Entamoeba histolytica protein kinase domain containing protein 0.0052 0.0097 0.061
Echinococcus granulosus serine/threonine protein kinase 0.0061 0.0124 0.0146
Brugia malayi Protein kinase domain containing protein 0.0052 0.0097 0.0095
Loa Loa (eye worm) hypothetical protein 0.012 0.0309 0.0309
Schistosoma mansoni regulator of G protein signaling 0.0521 0.1565 0.1564
Schistosoma mansoni cell adhesion molecule 0.012 0.0309 0.0308
Schistosoma mansoni tyrosine kinase 0.0052 0.0097 0.0095
Loa Loa (eye worm) TK/INSR protein kinase 0.0052 0.0097 0.0097
Brugia malayi Probable tyrosine-protein kinase kin-31 0.0052 0.0097 0.0095
Entamoeba histolytica protein kinase domain containing protein 0.0052 0.0097 0.061
Schistosoma mansoni dynamin 0.0048 0.0083 0.0081
Brugia malayi PH domain containing protein 0.0048 0.0083 0.0081
Loa Loa (eye worm) hypothetical protein 0.0029 0.0023 0.0023
Echinococcus multilocularis macrophage colony stimulating factor 1 receptor 0.0052 0.0097 0.0114
Echinococcus multilocularis retinal guanylyl cyclase 2 0.0052 0.0097 0.0114
Plasmodium vivax PH domain containing protein 0.0048 0.0083 0.518
Giardia lamblia Kinase 0.0052 0.0097 0.6028
Entamoeba histolytica serine/threonine- protein kinase 6, putative 0.0072 0.016 0.1013
Entamoeba histolytica protein kinase domain containing protein 0.0065 0.0138 0.0871
Schistosoma mansoni tyrosine kinase 0.0052 0.0097 0.0095
Trichomonas vaginalis centaurin alpha, putative 0.0048 0.0083 0.052
Echinococcus multilocularis semaphorin 5B 0.0336 0.0986 0.1176
Loa Loa (eye worm) TK/FER protein kinase 0.0052 0.0097 0.0097
Brugia malayi Syntrophin-1 0.0048 0.0083 0.0081
Loa Loa (eye worm) hypothetical protein 0.0048 0.0083 0.0083
Echinococcus granulosus collagen type iv alpha 3 binding protein 0.0048 0.0083 0.0097
Echinococcus multilocularis proto oncogene tyrosine protein kinase LCK 0.0052 0.0097 0.0114
Mycobacterium ulcerans hypothetical protein 0.0029 0.0023 1
Trypanosoma cruzi PH domain containing protein, putative 0.0048 0.0083 0.5138
Schistosoma mansoni regulator of G protein signaling 0.0521 0.1565 0.1564
Entamoeba histolytica tyrosine kinase, putative 0.0052 0.0097 0.061
Brugia malayi Protein kinase domain containing protein 0.0052 0.0097 0.0095
Loa Loa (eye worm) hypothetical protein 0.0028 0.0021 0.0021
Entamoeba histolytica tyrosine kinase, putative 0.0052 0.0097 0.061
Trichomonas vaginalis conserved hypothetical protein 0.0521 0.1565 1
Echinococcus granulosus Niemann Pick C1 protein 0.0119 0.0305 0.0363
Entamoeba histolytica hypothetical protein 0.0048 0.0083 0.052
Brugia malayi Niemann-Pick C1 protein precursor 0.0119 0.0305 0.0304
Trichomonas vaginalis conserved hypothetical protein 0.0147 0.0394 0.2512
Onchocerca volvulus 0.0033 0.0036 0.0063
Trichomonas vaginalis Clan MA, family M8, leishmanolysin-like metallopeptidase 0.0147 0.0394 0.2512
Loa Loa (eye worm) hypothetical protein 0.0048 0.0083 0.0083
Onchocerca volvulus Tyrosine kinase receptor Cad96Ca homolog 0.0052 0.0097 0.032
Entamoeba histolytica Rho guanine nucleotide exchange factor, putative 0.0048 0.0083 0.052
Echinococcus multilocularis Immunoglobulin 0.0115 0.0294 0.035
Entamoeba histolytica protein kinase, putative 0.0052 0.0097 0.061
Echinococcus granulosus neuroglian 0.0115 0.0294 0.035
Loa Loa (eye worm) TK/FAK protein kinase 0.0052 0.0097 0.0097
Onchocerca volvulus 0.0029 0.0023 0.0009
Trichomonas vaginalis TKL family protein kinase 0.0052 0.0097 0.061
Entamoeba histolytica protein kinase domain containing protein 0.0052 0.0097 0.061
Entamoeba histolytica tyrosine- protein kinase 2, putative 0.0052 0.0097 0.061
Trichomonas vaginalis conserved hypothetical protein 0.0048 0.0083 0.052
Echinococcus multilocularis protein tyrosine kinase 0.0052 0.0097 0.0114
Echinococcus granulosus dynamin 1 0.0048 0.0083 0.0097
Echinococcus granulosus mitogen activated protein kinase kinase kinase 0.0052 0.0097 0.0114
Loa Loa (eye worm) TK protein kinase 0.0052 0.0097 0.0097
Loa Loa (eye worm) hypothetical protein 0.0048 0.0083 0.0083
Entamoeba histolytica protein kinase domain containing protein 0.0052 0.0097 0.061
Trypanosoma brucei rac serine-threonine kinase, putative 0.0061 0.0124 0.7713
Schistosoma mansoni tyrosine kinase 0.0052 0.0097 0.0095
Brugia malayi CHE-14 protein 0.0051 0.0093 0.0091
Echinococcus granulosus oxysterol binding protein 3 0.0048 0.0083 0.0097
Leishmania major protein kinase, putative 0.0061 0.0124 0.7713
Brugia malayi protein-tyrosine kinase 0.0052 0.0097 0.0095
Loa Loa (eye worm) TK/FER protein kinase 0.0052 0.0097 0.0097
Trichomonas vaginalis TKL family protein kinase 0.0052 0.0097 0.061
Echinococcus multilocularis GRB2 associated binding protein 3 0.0048 0.0083 0.0097
Brugia malayi Protein kinase domain containing protein 0.0052 0.0097 0.0095
Loa Loa (eye worm) hypothetical protein 0.0052 0.0097 0.0097
Entamoeba histolytica acyl-CoA synthetase, putative 0.0029 0.0023 0.0136
Loa Loa (eye worm) TK/CSK protein kinase 0.0052 0.0097 0.0097
Entamoeba histolytica serine/threonine kinase, putative 0.0052 0.0097 0.061
Entamoeba histolytica serine/threonine kinase, putative 0.0052 0.0097 0.061
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0052 0.0097 0.0114
Loa Loa (eye worm) hypothetical protein 0.006 0.0122 0.0122
Toxoplasma gondii FATC domain-containing protein 0.003 0.0027 0.1613
Onchocerca volvulus 0.0791 0.241 1
Schistosoma mansoni oxysterol-binding protein 1 0.0048 0.0083 0.0081
Loa Loa (eye worm) RGC/RGC protein kinase 0.0052 0.0097 0.0097
Trichomonas vaginalis TKL family protein kinase 0.0052 0.0097 0.061
Echinococcus multilocularis Pleckstrin y 0.0048 0.0083 0.0097
Loa Loa (eye worm) hypothetical protein 0.0048 0.0083 0.0083
Entamoeba histolytica protein kinase, putative 0.0072 0.016 0.1013
Onchocerca volvulus Tyrosine kinase homolog 0.0052 0.0097 0.032
Brugia malayi Tyrosine-protein kinase abl-1 0.0052 0.0097 0.0095
Echinococcus multilocularis dynamin 1 0.0048 0.0083 0.0097
Echinococcus granulosus defective proboscis extension response 0.0115 0.0294 0.035
Schistosoma mansoni hypothetical protein 0.0048 0.0083 0.0081
Schistosoma mansoni tyrosine kinase 0.0052 0.0097 0.0095
Brugia malayi serine/threonine kinase 12 0.0072 0.016 0.0158
Trichomonas vaginalis TKL family protein kinase 0.0052 0.0097 0.061
Echinococcus granulosus tyrosine protein kinase Lyn 0.0065 0.0138 0.0163
Trichomonas vaginalis conserved hypothetical protein 0.0521 0.1565 1
Schistosoma mansoni tyrosine-protein kinase fps85d 0.0052 0.0097 0.0095
Trichomonas vaginalis conserved hypothetical protein 0.0147 0.0394 0.2512
Loa Loa (eye worm) TK/FER protein kinase 0.0052 0.0097 0.0097
Echinococcus multilocularis cytohesin 1 0.0048 0.0083 0.0097
Loa Loa (eye worm) voltage and ligand gated potassium channel 0.0039 0.0055 0.0055
Loa Loa (eye worm) hypothetical protein 0.0115 0.0294 0.0294
Echinococcus granulosus protein kinase 0.0052 0.0097 0.0114
Schistosoma mansoni ataxia telangiectasia mutated (atm) 0.003 0.0027 0.0026
Entamoeba histolytica Rho guanine nucleotide exchange factor, putative 0.0048 0.0083 0.052
Loa Loa (eye worm) hypothetical protein 0.0048 0.0083 0.0083
Echinococcus multilocularis plexin a4 0.0938 0.2871 0.343
Entamoeba histolytica protein kinase domain containing protein 0.0052 0.0097 0.061
Echinococcus granulosus oxysterol binding protein 1 0.0048 0.0083 0.0097
Trichomonas vaginalis TKL family protein kinase 0.0052 0.0097 0.061
Loa Loa (eye worm) TK/FER protein kinase 0.0052 0.0097 0.0097
Entamoeba histolytica Rho guanine nucleotide exchange factor, putative 0.0048 0.0083 0.052
Echinococcus granulosus tyrosine protein kinase transmembrane receptor 0.0052 0.0097 0.0114
Brugia malayi IPT/TIG domain containing protein 0.0147 0.0394 0.0393
Echinococcus multilocularis A kinase anchor protein 10, mitochondrial 0.0521 0.1565 0.1869
Loa Loa (eye worm) RGS-3 protein 0.0521 0.1565 0.1565
Plasmodium falciparum PH domain-containing protein, putative 0.0048 0.0083 0.518
Toxoplasma gondii Oxysterol-binding protein 0.0048 0.0083 0.5138
Trichomonas vaginalis TKL family protein kinase 0.0052 0.0097 0.061
Trichomonas vaginalis 3-phosphoinositide dependent protein kinase-1, putative 0.0061 0.0124 0.0781
Trichomonas vaginalis TKL family protein kinase 0.0052 0.0097 0.061
Brugia malayi regulator of G-protein signaling rgs-7 0.0521 0.1565 0.1564
Brugia malayi GTPase-activator protein for Ras-like GTPase containing protein 0.0048 0.0083 0.0081
Plasmodium falciparum phosphatidylinositol transfer protein, putative 0.0048 0.0083 0.518
Schistosoma mansoni tyrosine kinase 0.0052 0.0097 0.0095
Entamoeba histolytica hypothetical protein 0.0052 0.0097 0.061
Echinococcus granulosus melanoma receptor tyrosine protein kinase 0.0052 0.0097 0.0114
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0029 0.0023 1
Loa Loa (eye worm) hypothetical protein 0.0052 0.0097 0.0097
Schistosoma mansoni tyrosine kinase 0.0052 0.0097 0.0095
Echinococcus granulosus regulator of G protein signaling 7 0.0521 0.1565 0.1869
Toxoplasma gondii protein kinase 0.0052 0.0097 0.6028
Entamoeba histolytica serine/threonine kinase, putative 0.0052 0.0097 0.061
Schistosoma mansoni oxysterol-binding protein 1 0.0048 0.0083 0.0081
Echinococcus granulosus beta 1 syntrophin 0.0048 0.0083 0.0097
Trichomonas vaginalis TKL family protein kinase 0.0052 0.0097 0.061
Entamoeba histolytica Niemann-Pick C1 protein, putative 0.0119 0.0305 0.1943
Entamoeba histolytica protein kinase domain containing protein 0.0052 0.0097 0.061
Plasmodium falciparum serine/threonine protein kinase, putative 0.0072 0.016 1
Loa Loa (eye worm) RGC/RGC protein kinase 0.0052 0.0097 0.0097
Loa Loa (eye worm) Plekhf2 protein 0.0048 0.0083 0.0083
Brugia malayi hypothetical protein 0.0521 0.1565 0.1564
Trypanosoma brucei protein kinase, putative 0.0061 0.0124 0.7713
Trichomonas vaginalis AGC family protein kinase 0.0061 0.0124 0.0781
Entamoeba histolytica hypothetical protein 0.0521 0.1565 1
Toxoplasma gondii protein kinase domain-containing protein 0.0061 0.0124 0.7713
Trichomonas vaginalis development and differentiation-enhancing factor, ddef, putative 0.0048 0.0083 0.052
Entamoeba histolytica ankyrin repeat protein 0.0052 0.0097 0.061
Echinococcus granulosus neurotracting:lsamp:neurotrimin:obcam 0.0115 0.0294 0.035
Trichomonas vaginalis AGC family protein kinase 0.0072 0.016 0.1013
Echinococcus multilocularis arf GAP with SH3 domain, ANK repeat and PH 0.0048 0.0083 0.0097
Entamoeba histolytica hypothetical protein 0.0052 0.0097 0.061
Mycobacterium ulcerans acyl-CoA synthetase 0.0029 0.0023 1
Plasmodium falciparum conserved Plasmodium protein, unknown function 0.0048 0.0083 0.518
Trichomonas vaginalis conserved hypothetical protein 0.0147 0.0394 0.2512
Schistosoma mansoni regulator of G protein signaling 0.0521 0.1565 0.1564
Brugia malayi Regulator of G protein signaling domain containing protein 0.0521 0.1565 0.1564
Schistosoma mansoni development and differentiation-enhancing factor ddef 0.0048 0.0083 0.0081
Schistosoma mansoni tyrosine kinase 0.0052 0.0097 0.0095
Echinococcus granulosus activin receptor type 0.0065 0.0138 0.0163
Schistosoma mansoni protein kinase 0.0052 0.0097 0.0095
Trichomonas vaginalis centaurin/arf, putative 0.0048 0.0083 0.052
Entamoeba histolytica receptor protein kinase, putative 0.0052 0.0097 0.061
Echinococcus granulosus dual specificity testis-specific protein kinase 0.0065 0.0138 0.0163
Loa Loa (eye worm) hypothetical protein 0.0147 0.0394 0.0394
Brugia malayi proto-oncogene tyrosine-protein kinase FER 0.0052 0.0097 0.0095
Entamoeba histolytica hypothetical protein 0.0052 0.0097 0.061
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0052 0.0097 0.061
Leishmania major protein kinase, putative 0.0061 0.0124 0.7713
Trichomonas vaginalis TKL family protein kinase 0.0052 0.0097 0.061
Echinococcus multilocularis activated cdc42 kinase 1 0.0052 0.0097 0.0114
Loa Loa (eye worm) hypothetical protein 0.0521 0.1565 0.1565
Entamoeba histolytica hypothetical protein 0.0052 0.0097 0.061
Onchocerca volvulus 0.0052 0.0097 0.032
Echinococcus granulosus insulin receptor 0.0052 0.0097 0.0114
Brugia malayi Cadps2 protein 0.0048 0.0083 0.0081
Loa Loa (eye worm) TK/FER protein kinase 0.0052 0.0097 0.0097
Leishmania major serine/threonine-protein kinase a, putative 0.0061 0.0124 0.7713
Giardia lamblia Kinase, NEK 0.0052 0.0097 0.6028
Trichomonas vaginalis conserved hypothetical protein 0.0521 0.1565 1
Brugia malayi Immunoglobulin I-set domain containing protein 0.0168 0.0458 0.0457
Loa Loa (eye worm) pigment dispersing factor receptor c 0.006 0.0122 0.0122
Schistosoma mansoni tyrosine kinase 0.0052 0.0097 0.0095
Schistosoma mansoni hypothetical protein 0.0048 0.0083 0.0081
Loa Loa (eye worm) TK/DDR protein kinase 0.0052 0.0097 0.0097
Trypanosoma cruzi protein kinase, putative 0.0052 0.0097 0.6028
Echinococcus multilocularis axis inhibition protein axin 0.0521 0.1565 0.1869
Toxoplasma gondii protein kinase domain-containing protein 0.0052 0.0097 0.6028
Entamoeba histolytica SH2-protein kinase domain containing protein 0.0052 0.0097 0.061
Echinococcus granulosus tyrosine kinase 0.0052 0.0097 0.0114
Echinococcus multilocularis tyrosine protein kinase Src42A 0.0052 0.0097 0.0114
Trichomonas vaginalis conserved hypothetical protein 0.0052 0.0097 0.061
Trichomonas vaginalis AGC family protein kinase 0.0061 0.0124 0.0781
Brugia malayi AMP-binding enzyme family protein 0.0029 0.0023 0.0021
Trypanosoma brucei PH domain containing protein, putative 0.0048 0.0083 0.5138
Schistosoma mansoni serine/threonine protein kinase 0.0052 0.0097 0.0095
Echinococcus granulosus proto oncogene tyrosine protein kinase LCK 0.0052 0.0097 0.0114
Trichomonas vaginalis AGC family protein kinase 0.0061 0.0124 0.0781
Trichomonas vaginalis ankyrin 2,3/unc44, putative 0.0048 0.0083 0.052
Trichomonas vaginalis PIKK family atypical protein kinase 0.003 0.0027 0.0163
Entamoeba histolytica protein kinase with ankyrin repeats, putative 0.0052 0.0097 0.061
Toxoplasma gondii aurora kinase 0.0072 0.016 1
Brugia malayi Immunoglobulin I-set domain containing protein 0.0052 0.0097 0.0095
Echinococcus multilocularis roundabout 2 0.012 0.0309 0.0368
Echinococcus granulosus Protein patched homolog 1 0.0051 0.0093 0.0109
Loa Loa (eye worm) hypothetical protein 0.0336 0.0986 0.0986
Echinococcus granulosus axis inhibition protein axin 0.0521 0.1565 0.1869
Trichomonas vaginalis AGC family protein kinase 0.0061 0.0124 0.0781
Loa Loa (eye worm) hypothetical protein 0.0336 0.0986 0.0986
Trypanosoma brucei STE/STE11 serine/threonine-protein kinase, putative 0.0065 0.0138 0.8603
Schistosoma mansoni serine/threonine protein kinase 0.0052 0.0097 0.0095
Trichomonas vaginalis CAMK family protein kinase 0.0052 0.0097 0.061
Trichomonas vaginalis TKL family protein kinase 0.0052 0.0097 0.061
Brugia malayi hypothetical protein 0.0521 0.1565 0.1564
Trichomonas vaginalis conserved hypothetical protein 0.0051 0.0093 0.0584
Trypanosoma cruzi Serine/threonine-protein kinase NEK17, putative 0.0061 0.0124 0.7713
Entamoeba histolytica protein kinase, putative 0.0061 0.0124 0.0781
Brugia malayi Guanylyl cyclase protein 23 0.0052 0.0097 0.0095
Trichomonas vaginalis conserved hypothetical protein 0.0048 0.0083 0.052
Echinococcus multilocularis neuroglian 0.0115 0.0294 0.035
Echinococcus granulosus oxysterol binding protein 9 0.0048 0.0083 0.0097
Trichomonas vaginalis centaurin/arf, putative 0.0048 0.0083 0.052
Loa Loa (eye worm) TK/EGFR protein kinase 0.0052 0.0097 0.0097
Echinococcus multilocularis regulator of G protein signaling 3 0.0521 0.1565 0.1869
Schistosoma mansoni tyrosine kinase 0.0052 0.0097 0.0095
Loa Loa (eye worm) TK protein kinase 0.0052 0.0097 0.0097
Trypanosoma brucei phosphatidylinositol kinase related protein, putative 0.003 0.0027 0.1613
Schistosoma mansoni tyrosine kinase 0.0052 0.0097 0.0095
Brugia malayi MAX-1A 0.0048 0.0083 0.0081
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0052 0.0097 0.061
Schistosoma mansoni protein kinase 0.0052 0.0097 0.0095
Entamoeba histolytica Rho guanine nucleotide exchange factor, putative 0.0048 0.0083 0.052
Brugia malayi Protein kinase domain containing protein 0.0052 0.0097 0.0095
Echinococcus multilocularis regulator of G protein signaling 3 0.0521 0.1565 0.1869
Echinococcus granulosus raf serine:threonine protein kinase 0.0052 0.0097 0.0114
Entamoeba histolytica PH domain containing protein kinase, putative 0.0061 0.0124 0.0781
Entamoeba histolytica Rho guanine nucleotide exchange factor, putative 0.0048 0.0083 0.052
Loa Loa (eye worm) TK/FER protein kinase 0.0052 0.0097 0.0097
Entamoeba histolytica protein kinase, putative 0.0052 0.0097 0.061
Trichomonas vaginalis conserved hypothetical protein 0.0048 0.0083 0.052
Schistosoma mansoni hypothetical protein 0.0048 0.0083 0.0081
Echinococcus multilocularis G protein coupled receptor kinase 1 0.1943 0.6018 0.7191
Trichomonas vaginalis ankyrin repeat-containing protein, putative 0.0052 0.0097 0.061
Brugia malayi Protein kinase domain containing protein 0.0052 0.0097 0.0095
Onchocerca volvulus 0.0052 0.0097 0.032
Echinococcus granulosus twitchin 0.0128 0.0335 0.0399
Trichomonas vaginalis TKL family protein kinase 0.0052 0.0097 0.061
Brugia malayi Adenylate and Guanylate cyclase catalytic domain containing protein 0.0052 0.0097 0.0095
Echinococcus granulosus tyrosine protein kinase pr2 0.0052 0.0097 0.0114
Schistosoma mansoni nephrin 0.012 0.0309 0.0308
Echinococcus multilocularis tyrosine protein kinase 0.0052 0.0097 0.0114
Trichomonas vaginalis TKL family protein kinase 0.0052 0.0097 0.061
Brugia malayi PXA domain containing protein 0.0521 0.1565 0.1564
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0052 0.0097 0.061
Trichomonas vaginalis TKL family protein kinase 0.0052 0.0097 0.061
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD2 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0029 0.0023 1
Echinococcus multilocularis ephrin type A receptor 4 A 0.0052 0.0097 0.0114
Brugia malayi PH domain containing protein 0.0048 0.0083 0.0081
Echinococcus multilocularis tyrosine protein kinase Abl 0.0052 0.0097 0.0114
Brugia malayi Protein kinase domain containing protein 0.0052 0.0097 0.0095
Entamoeba histolytica protein kinase domain containing protein 0.0052 0.0097 0.061
Entamoeba histolytica tyrosine kinase, putative 0.0052 0.0097 0.061
Loa Loa (eye worm) abnormal chemotaxis protein 14 0.0051 0.0093 0.0093
Loa Loa (eye worm) hypothetical protein 0.0051 0.0093 0.0093
Trichomonas vaginalis br serine/threonine-protein kinase, putative 0.0052 0.0097 0.061
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0052 0.0097 0.061
Loa Loa (eye worm) TK/FER protein kinase 0.0052 0.0097 0.0097
Echinococcus granulosus insulin growth factor 1 receptor beta 0.0057 0.0112 0.0132
Trypanosoma cruzi NIMA-related kinase, putative 0.0061 0.0124 0.7713
Schistosoma mansoni goodpasture antigen-binding protein 0.0048 0.0083 0.0081
Schistosoma mansoni defective proboscis extension response (dpr)-related 0.0115 0.0294 0.0293
Schistosoma mansoni tyrosine kinase 0.0052 0.0097 0.0095
Loa Loa (eye worm) hypothetical protein 0.0048 0.0083 0.0083
Schistosoma mansoni regulator of G protein signaling 17 19 20 (rgs17 19 20) 0.0521 0.1565 0.1564
Loa Loa (eye worm) GTP-ase activating protein for Arf containing protein 0.0048 0.0083 0.0083
Echinococcus multilocularis pleckstrin y domain containing family A 0.0048 0.0083 0.0097
Loa Loa (eye worm) RGC/RGC protein kinase 0.0052 0.0097 0.0097
Echinococcus multilocularis oxysterol binding protein 9 0.0048 0.0083 0.0097
Entamoeba histolytica PH domain containing protein 0.0048 0.0083 0.052
Echinococcus multilocularis atrial natriuretic peptide receptor 1 0.0052 0.0097 0.0114
Loa Loa (eye worm) syntrophin-1 0.0048 0.0083 0.0083
Trichomonas vaginalis AGC family protein kinase 0.0061 0.0124 0.0781
Loa Loa (eye worm) hypothetical protein 0.0048 0.0083 0.0083
Loa Loa (eye worm) TKL/MLK/ILK protein kinase 0.0052 0.0097 0.0097
Entamoeba histolytica tyrosine kinase, putative 0.0052 0.0097 0.061
Echinococcus multilocularis activin receptor type 0.0065 0.0138 0.0163
Loa Loa (eye worm) TKL/MLK/TAK1 protein kinase 0.0052 0.0097 0.0097
Echinococcus granulosus Pleckstrin y 0.0048 0.0083 0.0097
Toxoplasma gondii hypothetical protein 0.0048 0.0083 0.5138
Trichomonas vaginalis TKL family protein kinase 0.0052 0.0097 0.061
Echinococcus granulosus tyrosine protein kinase csk 0.0052 0.0097 0.0114
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0052 0.0097 0.0114
Loa Loa (eye worm) hypothetical protein 0.0062 0.0129 0.0129
Loa Loa (eye worm) RGC/RGC protein kinase 0.0052 0.0097 0.0097
Entamoeba histolytica protein kinase, putative 0.0052 0.0097 0.061
Entamoeba histolytica protein kinase domain containing protein 0.02 0.0558 0.3559
Entamoeba histolytica hypothetical protein, conserved domain containing 0.0048 0.0083 0.052
Entamoeba histolytica PH domain containing protein kinase, putative 0.0061 0.0124 0.0781
Schistosoma mansoni tyrosine kinase 0.0052 0.0097 0.0095
Trichomonas vaginalis conserved hypothetical protein 0.0052 0.0097 0.061
Trypanosoma cruzi NEK family Serine/threonine-protein kinase, putative 0.0048 0.0083 0.5138
Entamoeba histolytica hypothetical protein 0.0147 0.0394 0.2512
Trichomonas vaginalis TKL family protein kinase 0.0052 0.0097 0.061
Entamoeba histolytica PH domain containing protein 0.0048 0.0083 0.052
Trichomonas vaginalis TKL family protein kinase 0.0052 0.0097 0.061
Schistosoma mansoni tyrosine kinase 0.0052 0.0097 0.0095
Trichomonas vaginalis TKL family protein kinase 0.0052 0.0097 0.061
Schistosoma mansoni src-type protein tyrosine kinase-related 0.0052 0.0097 0.0095
Onchocerca volvulus 0.0052 0.0097 0.032
Entamoeba histolytica hypothetical protein 0.003 0.0027 0.0163
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0052 0.0097 0.061
Trypanosoma cruzi PH domain containing protein, putative 0.0048 0.0083 0.5138
Loa Loa (eye worm) G protein-coupled receptor kinase 1 0.2694 0.8368 0.8368
Brugia malayi AMP-binding enzyme family protein 0.0029 0.0023 0.0021
Giardia lamblia Protein 21.1 0.0052 0.0097 0.6028
Entamoeba histolytica protein kinase, putative 0.0052 0.0097 0.061
Entamoeba histolytica protein kinase domain containing protein 0.0052 0.0097 0.061
Entamoeba histolytica tyrosine kinase, putative 0.0052 0.0097 0.061
Entamoeba histolytica hypothetical protein 0.0521 0.1565 1
Trypanosoma cruzi PH domain containing protein, putative 0.0048 0.0083 0.5138
Trichomonas vaginalis kinesin light chain, putative 0.0048 0.0083 0.052
Brugia malayi Pleckstrin Homology Domain 0.0048 0.0083 0.0081
Echinococcus granulosus Immunoglobulin 0.0115 0.0294 0.035
Echinococcus multilocularis Niemann Pick C1 protein 0.0119 0.0305 0.0363
Entamoeba histolytica Rho guanine nucleotide exchange factor, putative 0.0048 0.0083 0.052
Echinococcus multilocularis tyrosine protein kinase Fes:Fps 0.0052 0.0097 0.0114
Loa Loa (eye worm) hypothetical protein 0.0205 0.0576 0.0576
Loa Loa (eye worm) hypothetical protein 0.0052 0.0097 0.0097
Echinococcus granulosus roundabout 2 0.012 0.0309 0.0368
Echinococcus multilocularis Arf GAP and Pleckstrin domain containing protein 0.0048 0.0083 0.0097
Echinococcus granulosus tyrosine protein kinase Fes:Fps 0.0052 0.0097 0.0114
Schistosoma mansoni tyrosine protein kinase fes (fps) (ptk group IV) 0.0052 0.0097 0.0095
Echinococcus multilocularis transcription factor collier 0.0147 0.0394 0.0469
Entamoeba histolytica Rho guanine nucleotide exchange factor, putative 0.0048 0.0083 0.052
Entamoeba histolytica hypothetical protein 0.0052 0.0097 0.061
Echinococcus granulosus Oxysterol binding protein 11 0.0048 0.0083 0.0097
Brugia malayi Protein kinase domain containing protein 0.0052 0.0097 0.0095
Leishmania major 4-coumarate:coa ligase-like protein 0.0029 0.0023 0.1342
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0043 0.0069 0.0081
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0052 0.0097 0.061
Loa Loa (eye worm) hypothetical protein 0.0052 0.0097 0.0097
Echinococcus multilocularis kinase suppressor of Ras 1 0.0052 0.0097 0.0114
Plasmodium vivax hypothetical protein, conserved 0.0048 0.0083 0.518
Trypanosoma cruzi aurora B kinase, putative 0.0072 0.016 1
Loa Loa (eye worm) hypothetical protein 0.0052 0.0097 0.0097
Entamoeba histolytica p21-activated kinase 0.0061 0.0124 0.0781
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0052 0.0097 0.0114
Entamoeba histolytica hypothetical protein 0.0061 0.0124 0.0781
Trichomonas vaginalis AGC family protein kinase 0.0061 0.0124 0.0781
Trypanosoma cruzi Serine/threonine-protein kinase NEK21, putative 0.0061 0.0124 0.7713
Trichomonas vaginalis AGC family protein kinase 0.0061 0.0124 0.0781
Plasmodium vivax protein kinase, putative 0.0052 0.0097 0.6063
Entamoeba histolytica tyrosine kinase, putative 0.0052 0.0097 0.061
Leishmania major folate/biopterin transporter, putative 0.0061 0.0124 0.7713
Schistosoma mansoni z-protein (S1r protein) 0.0521 0.1565 0.1564
Echinococcus granulosus cytohesin 1 0.0048 0.0083 0.0097
Trichomonas vaginalis conserved hypothetical protein 0.0052 0.0097 0.061
Leishmania major protein kinase, putative 0.0065 0.0138 0.8603
Entamoeba histolytica protein kinase, putative 0.0052 0.0097 0.061
Entamoeba histolytica acyl-coA synthetase, putative 0.0029 0.0023 0.0136
Entamoeba histolytica Rho guanine nucleotide exchange factor, putative 0.0048 0.0083 0.052
Schistosoma mansoni tyrosine-protein kinase fps85d 0.0052 0.0097 0.0095
Brugia malayi bone morphogenetic protein type 1 receptor 0.0052 0.0097 0.0095
Entamoeba histolytica hypothetical protein 0.0052 0.0097 0.061
Echinococcus multilocularis epidermal growth factor receptor 0.0052 0.0097 0.0114
Mycobacterium ulcerans acyl-CoA synthetase 0.0029 0.0023 1
Echinococcus multilocularis pdz domain containing protein 0.0048 0.0083 0.0097
Echinococcus granulosus tyrosine protein kinase Btk29A 0.0052 0.0097 0.0114
Loa Loa (eye worm) RhoGEF domain-containing protein 0.0048 0.0083 0.0083
Echinococcus multilocularis collagen type iv alpha 3 binding protein 0.0048 0.0083 0.0097
Onchocerca volvulus 0.0048 0.0083 0.0261
Entamoeba histolytica protein kinase, putative 0.0052 0.0097 0.061
Echinococcus multilocularis protein kinase 0.0052 0.0097 0.0114
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0036 0.0047 0.0293
Entamoeba histolytica protein kinase, putative 0.0052 0.0097 0.061
Trichomonas vaginalis TKL family protein kinase 0.0052 0.0097 0.061
Loa Loa (eye worm) TK/ROR protein kinase 0.0052 0.0097 0.0097
Trichomonas vaginalis TKL family protein kinase 0.0052 0.0097 0.061
Echinococcus multilocularis tyrosine protein kinase transmembrane receptor 0.0052 0.0097 0.0114
Loa Loa (eye worm) TK protein kinase 0.0052 0.0097 0.0097
Trypanosoma cruzi NIMA-related kinase, putative 0.0061 0.0124 0.7713
Trichomonas vaginalis conserved hypothetical protein 0.0048 0.0083 0.052
Trypanosoma cruzi ADP-ribosylation factor family, putative 0.0048 0.0083 0.5138
Onchocerca volvulus 0.0052 0.0097 0.032
Trichomonas vaginalis AGC family protein kinase 0.0052 0.0097 0.061
Echinococcus granulosus tyrosine protein kinase shark 0.0052 0.0097 0.0114
Brugia malayi ephrin receptor 1 precursor 0.0052 0.0097 0.0095
Trichomonas vaginalis AGC family protein kinase 0.0061 0.0124 0.0781
Brugia malayi Uncoordinated protein 104 0.0048 0.0083 0.0081
Echinococcus granulosus expressed conserved protein 0.0112 0.0283 0.0336
Brugia malayi GTP-ase activating protein for Arf containing protein 0.0048 0.0083 0.0081
Echinococcus granulosus integrin linked protein kinase 0.0052 0.0097 0.0114
Trichomonas vaginalis TKL family protein kinase 0.0052 0.0097 0.061
Loa Loa (eye worm) TK/RYK protein kinase 0.0052 0.0097 0.0097
Loa Loa (eye worm) TKL/MLK/HH498 protein kinase 0.0052 0.0097 0.0097
Trichomonas vaginalis AGC family protein kinase 0.0061 0.0124 0.0781
Entamoeba histolytica protein kinase, putative 0.0061 0.0124 0.0781
Trichomonas vaginalis AGC family protein kinase 0.0072 0.016 0.1013
Leishmania major hypothetical protein, conserved 0.0052 0.0097 0.6028
Echinococcus granulosus tyrosine protein kinase Fyn 0.0052 0.0097 0.0114
Loa Loa (eye worm) hypothetical protein 0.0048 0.0083 0.0083
Echinococcus granulosus tyrosine protein kinase Btk29A 0.0052 0.0097 0.0114
Entamoeba histolytica protein kinase, putative 0.0061 0.0124 0.0781
Brugia malayi Protein kinase domain containing protein 0.0052 0.0097 0.0095
Trypanosoma cruzi Protein kinase B 0.0061 0.0124 0.7713
Schistosoma mansoni tyrosine kinase 0.0052 0.0097 0.0095
Entamoeba histolytica hypothetical protein 0.0048 0.0083 0.052
Schistosoma mansoni serine/threonine protein kinase 0.0052 0.0097 0.0095
Schistosoma mansoni hypothetical protein 0.0048 0.0083 0.0081
Loa Loa (eye worm) hypothetical protein 0.0052 0.0097 0.0097
Trichomonas vaginalis AGC family protein kinase 0.0061 0.0124 0.0781
Loa Loa (eye worm) TK/EPH protein kinase 0.0052 0.0097 0.0097
Brugia malayi Probable tyrosine-protein kinase kin-31 0.0052 0.0097 0.0095
Loa Loa (eye worm) hypothetical protein 0.0048 0.0083 0.0083
Trichomonas vaginalis conserved hypothetical protein 0.0048 0.0083 0.052
Echinococcus multilocularis tyrosine protein kinase csk 0.0052 0.0097 0.0114
Loa Loa (eye worm) hypothetical protein 0.0052 0.0097 0.0097
Trichomonas vaginalis AGC family protein kinase 0.0061 0.0124 0.0781
Echinococcus multilocularis protein dispatched 1 0.0058 0.0115 0.0136
Trichomonas vaginalis TKL family protein kinase 0.0052 0.0097 0.061
Trichomonas vaginalis TKL family protein kinase 0.0052 0.0097 0.061
Entamoeba histolytica hypothetical protein 0.0043 0.0069 0.0433
Loa Loa (eye worm) TKL/STKR/TYPE1 protein kinase 0.0052 0.0097 0.0097
Trichomonas vaginalis TKL family protein kinase 0.0052 0.0097 0.061
Entamoeba histolytica tyrosine kinase, putative 0.0052 0.0097 0.061
Trypanosoma brucei serine/threonine-protein kinase NRKB, putative 0.0061 0.0124 0.7713
Echinococcus granulosus regulator of G protein signaling 3 0.0521 0.1565 0.1869
Brugia malayi Probable exocyst complex component Sec5 0.0147 0.0394 0.0393
Loa Loa (eye worm) hypothetical protein 0.0048 0.0083 0.0083
Echinococcus granulosus tyrosine protein kinase transmembrane receptor 0.0052 0.0097 0.0114
Brugia malayi AMP-binding enzyme family protein 0.0029 0.0023 0.0021
Entamoeba histolytica protein kinase, putative 0.0052 0.0097 0.061
Trichomonas vaginalis TKL family protein kinase 0.0052 0.0097 0.061
Entamoeba histolytica hypothetical protein 0.0048 0.0083 0.052
Trichomonas vaginalis TKL family protein kinase 0.0052 0.0097 0.061
Entamoeba histolytica protein kinase, putative 0.0052 0.0097 0.061
Entamoeba histolytica protein kinase, putative 0.0061 0.0124 0.0781
Echinococcus multilocularis tyrosine protein kinase Btk29A 0.0052 0.0097 0.0114
Brugia malayi Dynamin 0.0048 0.0083 0.0081
Brugia malayi hypothetical protein 0.0336 0.0986 0.0984
Loa Loa (eye worm) TK/FER protein kinase 0.0052 0.0097 0.0097
Trichomonas vaginalis conserved hypothetical protein 0.0052 0.0097 0.061
Loa Loa (eye worm) phosphatidylinositol 3 0.0022 0.0001 0.0001
Echinococcus granulosus tyrosine kinase|tyrosine protein kinase Fyn 0.0052 0.0097 0.0114
Schistosoma mansoni Neurotrimin precursor (hNT) 0.0115 0.0294 0.0293
Echinococcus multilocularis beta adrenergic receptor kinase 0.2465 0.765 0.9142
Echinococcus multilocularis basement membrane specific heparan sulfate 0.0115 0.0294 0.035
Schistosoma mansoni serine/threonine-protein kinase 0.0061 0.0124 0.0122
Entamoeba histolytica Rho guanine nucleotide exchange factor, putative 0.0048 0.0083 0.052
Echinococcus multilocularis Pleckstrin y 0.0048 0.0083 0.0097
Trichomonas vaginalis AGC family protein kinase 0.0061 0.0124 0.0781
Loa Loa (eye worm) AUR protein kinase 0.0072 0.016 0.016
Brugia malayi Protein kinase domain containing protein 0.0052 0.0097 0.0095
Echinococcus multilocularis oxysterol binding protein 3 0.0048 0.0083 0.0097
Entamoeba histolytica hypothetical protein 0.0052 0.0097 0.061
Trichomonas vaginalis Clan MA, family M8, leishmanolysin-like metallopeptidase 0.0147 0.0394 0.2512
Brugia malayi hypothetical protein 0.0336 0.0986 0.0984
Brugia malayi PH domain containing protein 0.0048 0.0083 0.0081
Trichomonas vaginalis protein tyrosine kinase, putative 0.0052 0.0097 0.061
Entamoeba histolytica tyrosine kinase, putative 0.0052 0.0097 0.061
Trichomonas vaginalis conserved hypothetical protein 0.0048 0.0083 0.052
Brugia malayi Protein kinase domain containing protein 0.0286 0.0828 0.0826
Echinococcus multilocularis Niemann Pick C1 protein 0.017 0.0465 0.0554
Schistosoma mansoni dynamin 0.0048 0.0083 0.0081
Trichomonas vaginalis AGC family protein kinase 0.0061 0.0124 0.0781
Entamoeba histolytica protein kinase domain containing protein 0.0052 0.0097 0.061
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD2 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0029 0.0023 0.5
Entamoeba histolytica acyl-CoA synthetase, putative 0.0029 0.0023 0.0136
Echinococcus granulosus tyrosine protein kinase Blk 0.0052 0.0097 0.0114
Trypanosoma cruzi rac serine-threonine kinase, putative 0.0061 0.0124 0.7713
Loa Loa (eye worm) hypothetical protein 0.0521 0.1565 0.1565
Schistosoma mansoni voltage-gated potassium channel 0.0043 0.0066 0.0065
Entamoeba histolytica hypothetical protein, conserved domain containing 0.0048 0.0083 0.052
Onchocerca volvulus 0.0048 0.0083 0.0261
Leishmania major protein kinase, putative,serine/threonine protein kinase, putative 0.0061 0.0124 0.7713
Schistosoma mansoni protein tyrosine kinase 0.0052 0.0097 0.0095
Brugia malayi Protein kinase domain containing protein 0.0052 0.0097 0.0095
Chlamydia trachomatis acylglycerophosphoethanolamine acyltransferase 0.0021 0 0.5
Schistosoma mansoni zinc finger protein 0.0048 0.0083 0.0081
Brugia malayi Protein kinase domain containing protein 0.0052 0.0097 0.0095
Echinococcus granulosus MAM 0.0028 0.0021 0.0023
Trypanosoma cruzi NEK family Serine/threonine-protein kinase, putative 0.0061 0.0124 0.7713
Onchocerca volvulus Atrial natriuretic peptide receptor 3 homolog 0.0052 0.0097 0.032
Loa Loa (eye worm) hypothetical protein 0.0052 0.0097 0.0097
Loa Loa (eye worm) hypothetical protein 0.0521 0.1565 0.1565
Loa Loa (eye worm) hypothetical protein 0.0052 0.0097 0.0097
Loa Loa (eye worm) uncoordinated protein 104 0.0048 0.0083 0.0083
Echinococcus multilocularis tyrosine protein kinase transmembrane receptor 0.0052 0.0097 0.0114
Entamoeba histolytica hypothetical protein 0.0052 0.0097 0.061
Trypanosoma cruzi STE/STE11 serine/threonine-protein kinase, putative 0.0065 0.0138 0.8603
Entamoeba histolytica cell surface protease gp63, putative 0.0147 0.0394 0.2512
Schistosoma mansoni hypothetical protein 0.0147 0.0394 0.0393
Echinococcus multilocularis c src tyrosine kinase 0.0052 0.0097 0.0114
Entamoeba histolytica protein kinase, putative 0.0052 0.0097 0.061
Echinococcus multilocularis tyrosine protein kinase Src64B 0.0052 0.0097 0.0114
Leishmania major rac serine-threonine kinase, putative,protein kinase, putative 0.0061 0.0124 0.7713
Entamoeba histolytica tyrosine kinase, putative 0.0052 0.0097 0.061
Schistosoma mansoni tyrosine kinase 0.0052 0.0097 0.0095
Toxoplasma gondii hypothetical protein 0.0048 0.0083 0.5138
Loa Loa (eye worm) TK/ALK protein kinase 0.0286 0.0827 0.0827
Onchocerca volvulus 0.0052 0.0097 0.032
Loa Loa (eye worm) TK protein kinase 0.0052 0.0097 0.0097
Trichomonas vaginalis AGC family protein kinase 0.0072 0.016 0.1013
Schistosoma mansoni vesicular amine transporter 0.0118 0.0302 0.0301
Onchocerca volvulus 0.0052 0.0097 0.032
Entamoeba histolytica protein kinase domain containing protein 0.0052 0.0097 0.061
Entamoeba histolytica protein kinase domain containing protein 0.0052 0.0097 0.061
Schistosoma mansoni plexin 0.0791 0.241 0.2409
Echinococcus multilocularis Pleckstrin domain containing protein, family B 0.0048 0.0083 0.0097
Schistosoma mansoni serine/threonine protein kinase 0.0072 0.016 0.0158
Brugia malayi GTP-ase activating protein for Arf containing protein 0.0048 0.0083 0.0081
Trichomonas vaginalis STE family protein kinase 0.0052 0.0097 0.061
Trypanosoma cruzi Serine/threonine-protein kinase NEK21, putative 0.0061 0.0124 0.7713
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0052 0.0097 0.061
Loa Loa (eye worm) hypothetical protein 0.0115 0.0294 0.0294
Echinococcus multilocularis oxysterol binding protein 1 0.0048 0.0083 0.0097
Trichomonas vaginalis AGC family protein kinase 0.0061 0.0124 0.0781
Loa Loa (eye worm) TK/FER protein kinase 0.0052 0.0097 0.0097
Trichomonas vaginalis conserved hypothetical protein 0.0052 0.0097 0.061
Brugia malayi Protein kinase domain containing protein 0.0052 0.0097 0.0095
Brugia malayi serine/threonine protein kinase 6 0.0072 0.016 0.0158
Onchocerca volvulus 0.0052 0.0097 0.032
Echinococcus multilocularis hypothetical protein 0.0336 0.0986 0.1176
Brugia malayi PH domain containing protein 0.0048 0.0083 0.0081
Echinococcus granulosus axis inhibition protein axin 0.0521 0.1565 0.1869
Entamoeba histolytica tyrosine kinase, putative 0.0052 0.0097 0.061
Loa Loa (eye worm) hypothetical protein 0.0115 0.0294 0.0294
Schistosoma mansoni tyrosine kinase 0.0052 0.0097 0.0095
Echinococcus multilocularis arf GAP with coiled coil, ANK repeat and PH 0.0048 0.0083 0.0097
Loa Loa (eye worm) hypothetical protein 0.0052 0.0097 0.0097
Loa Loa (eye worm) AGC/GRK/GRK protein kinase 0.2694 0.8368 0.8368
Brugia malayi Protein kinase domain containing protein 0.0052 0.0097 0.0095
Echinococcus granulosus tyrosine protein kinase Fyn 0.0052 0.0097 0.0114
Toxoplasma gondii calcium dependent protein kinase CDPK7 0.0061 0.0124 0.7713
Echinococcus multilocularis fibroblast growth factor receptor 4 0.0052 0.0097 0.0114
Loa Loa (eye worm) hypothetical protein 0.0336 0.0986 0.0986
Trypanosoma brucei protein kinase, putative 0.0065 0.0138 0.8603
Trichomonas vaginalis AGC family protein kinase 0.0061 0.0124 0.0781
Echinococcus multilocularis regulator of G protein signaling 7 0.0521 0.1565 0.1869
Echinococcus multilocularis actin binding protein anillin 0.0048 0.0083 0.0097
Trichomonas vaginalis conserved hypothetical protein 0.0521 0.1565 1
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0052 0.0097 0.061
Echinococcus multilocularis protein kinase 0.0052 0.0097 0.0114
Echinococcus multilocularis natriuretic peptide receptor 1 0.0052 0.0097 0.0114
Loa Loa (eye worm) rho-GTPase-activating 0.0048 0.0083 0.0083
Entamoeba histolytica hypothetical protein, conserved 0.0052 0.0097 0.061
Mycobacterium ulcerans long-chain fatty-acid CoA ligase 0.0029 0.0023 1
Trichomonas vaginalis TKL family protein kinase 0.0052 0.0097 0.061
Echinococcus multilocularis rac serine:threonine kinase 0.0061 0.0124 0.0146
Brugia malayi Protein kinase domain containing protein 0.0052 0.0097 0.0095
Brugia malayi Oxysterol-binding protein 0.0048 0.0083 0.0081
Echinococcus multilocularis serine:threonine protein kinase 12 B 0.0072 0.016 0.0189
Trichomonas vaginalis TKL family protein kinase 0.0052 0.0097 0.061
Schistosoma mansoni tyrosine kinase 0.0052 0.0097 0.0095
Trichomonas vaginalis TKL family protein kinase 0.0052 0.0097 0.061
Schistosoma mansoni fibrocystin l 0.0147 0.0394 0.0393
Echinococcus granulosus Regulator of G protein signaling 20 0.0521 0.1565 0.1869
Brugia malayi Protein kinase domain containing protein 0.0052 0.0097 0.0095
Echinococcus granulosus exocyst complex component 2 0.0147 0.0394 0.0469
Trichomonas vaginalis regulator of G protein signaling 5, rgs5, putative 0.0521 0.1565 1
Onchocerca volvulus 0.0052 0.0097 0.032
Trichomonas vaginalis centaurin gamma, putative 0.0048 0.0083 0.052
Brugia malayi Protein kinase domain containing protein 0.0052 0.0097 0.0095
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0052 0.0097 0.061
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0036 0.0047 0.0293
Entamoeba histolytica protein kinase domain containing protein 0.0052 0.0097 0.061
Echinococcus granulosus tyrosine protein kinase 0.0052 0.0097 0.0114
Entamoeba histolytica tyrosin kinase, putative 0.02 0.0558 0.3559
Trypanosoma cruzi hypothetical protein 0.0048 0.0083 0.5138
Trichomonas vaginalis alpha chimerin, putative 0.0048 0.0083 0.052
Trichomonas vaginalis conserved hypothetical protein 0.0147 0.0394 0.2512
Brugia malayi probable spectrin beta chain 0.0048 0.0083 0.0081
Trichomonas vaginalis TKL family protein kinase 0.0052 0.0097 0.061
Entamoeba histolytica protein kinase domain containing protein 0.0052 0.0097 0.061
Trichomonas vaginalis TKL family protein kinase 0.0052 0.0097 0.061
Brugia malayi hypothetical protein 0.0028 0.0021 0.0019
Trichomonas vaginalis TKL family protein kinase 0.0052 0.0097 0.061
Trichomonas vaginalis TKL family protein kinase 0.0052 0.0097 0.061
Loa Loa (eye worm) TK/KIN6 protein kinase 0.0052 0.0097 0.0097
Echinococcus multilocularis myotubularin protein 13 0.0048 0.0083 0.0097
Brugia malayi Fibronectin type III domain containing protein 0.012 0.0309 0.0308
Onchocerca volvulus 0.0052 0.0097 0.032
Loa Loa (eye worm) G protein signaling regulator EGL-10 0.0521 0.1565 0.1565
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0052 0.0097 0.0114
Brugia malayi Tyrosine-protein kinase F09A5.2 in chromosome X, putative 0.0052 0.0097 0.0095
Trypanosoma brucei Pseudokinase, putative 0.0052 0.0097 0.6028
Echinococcus granulosus A kinase anchor protein 10 mitochondrial 0.0521 0.1565 0.1869
Brugia malayi Protein kinase domain containing protein 0.0061 0.0124 0.0122
Echinococcus multilocularis regulator of G protein signaling 7 0.0521 0.1565 0.1869
Echinococcus multilocularis retinal guanylyl cyclase 2 0.0052 0.0097 0.0114
Loa Loa (eye worm) hypothetical protein 0.0048 0.0083 0.0083
Loa Loa (eye worm) hypothetical protein 0.0028 0.0021 0.0021
Entamoeba histolytica tyrosin kinase, putative 0.0052 0.0097 0.061
Entamoeba histolytica protein kinase, putative 0.0052 0.0097 0.061
Loa Loa (eye worm) hypothetical protein 0.0455 0.1358 0.1358
Onchocerca volvulus 0.0336 0.0986 0.4038
Entamoeba histolytica hypothetical protein 0.0521 0.1565 1
Leishmania major 4-coumarate:coa ligase-like protein 0.0029 0.0023 0.1342
Entamoeba histolytica protein kinase domain containing protein 0.0052 0.0097 0.061
Onchocerca volvulus 0.0048 0.0083 0.0261
Entamoeba histolytica serine/threonine kinase, putative 0.0052 0.0097 0.061
Echinococcus granulosus potassium voltage gated channel subfamily H 0.0039 0.0055 0.0064
Trichomonas vaginalis conserved hypothetical protein 0.0147 0.0394 0.2512
Echinococcus granulosus ephrin type A receptor 4 A 0.0052 0.0097 0.0114
Toxoplasma gondii Tyrosine kinase-like (TKL) protein 0.0052 0.0097 0.6028
Entamoeba histolytica hypothetical protein 0.0048 0.0083 0.052
Schistosoma mansoni proto-oncogene tyrosine-protein kinase src 0.0052 0.0097 0.0095
Schistosoma mansoni myotubularin-related protein 0.0048 0.0083 0.0081
Brugia malayi Immunoglobulin I-set domain containing protein 0.012 0.0309 0.0308
Trypanosoma cruzi hypothetical protein 0.0048 0.0083 0.5138
Brugia malayi DNA-binding protein LAG-1 0.0147 0.0394 0.0393
Leishmania major hypothetical protein, conserved 0.0048 0.0083 0.5138
Schistosoma mansoni growth factor receptor-bound protein 0.0048 0.0083 0.0081
Echinococcus multilocularis raf serine:threonine protein kinase 0.0052 0.0097 0.0114
Echinococcus multilocularis tyrosine protein kinase csk 0.0052 0.0097 0.0114
Trichomonas vaginalis AGC family protein kinase 0.0061 0.0124 0.0781
Trichomonas vaginalis AGC family protein kinase 0.0061 0.0124 0.0781
Schistosoma mansoni hypothetical protein 0.0049 0.0087 0.0086
Toxoplasma gondii STE kinase 0.0052 0.0097 0.6028
Loa Loa (eye worm) TK/FER protein kinase 0.0052 0.0097 0.0097
Trichomonas vaginalis serine-threonine protein kinase, putative 0.0052 0.0097 0.061
Echinococcus granulosus serine:threonine protein kinase 12 B 0.0072 0.016 0.0189
Plasmodium vivax tyrosine kinase-like protein, putative 0.0052 0.0097 0.6063
Entamoeba histolytica leucine-rich repeat domain-containing protein 0.0052 0.0097 0.061
Entamoeba histolytica tyrosine kinase, putative 0.0052 0.0097 0.061
Trypanosoma cruzi phosphatidylinositol kinase related protein, putative 0.0022 0.0002 0.0008
Echinococcus granulosus retinal guanylyl cyclase 2 0.0052 0.0097 0.0114
Entamoeba histolytica protein kinase domain containing protein 0.0052 0.0097 0.061
Entamoeba histolytica protein kinase, putative 0.0061 0.0124 0.0781
Echinococcus granulosus beta-adrenergic receptor kinase 0.2465 0.765 0.9142
Onchocerca volvulus 0.0048 0.0083 0.0261
Brugia malayi PXA domain containing protein 0.0521 0.1565 0.1564
Trichomonas vaginalis conserved hypothetical protein 0.0048 0.0083 0.052
Trichomonas vaginalis TKL family protein kinase 0.0052 0.0097 0.061
Echinococcus multilocularis Ras associated and pleckstrin y 0.0048 0.0083 0.0097
Trypanosoma cruzi hypothetical protein 0.0048 0.0083 0.5138
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD7 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0029 0.0023 0.5
Trichomonas vaginalis serine/threonine-protein kinase wnk, putative 0.0052 0.0097 0.061
Trichomonas vaginalis TKL family protein kinase 0.0052 0.0097 0.061
Echinococcus multilocularis tyrosine protein kinase lyn lyn a protein tyrosine kinase lymphocyte specific protein tyrosine kinase 0.0052 0.0097 0.0114
Giardia lamblia Kinase, NEK 0.0052 0.0097 0.6028
Echinococcus multilocularis ras specific guanine nucleotide releasing factor 0.0048 0.0083 0.0097
Echinococcus multilocularis Pleckstrin y 0.0048 0.0083 0.0097
Trichomonas vaginalis Clan MA, family M8, leishmanolysin-like metallopeptidase 0.0147 0.0394 0.2512
Trichomonas vaginalis AGC family protein kinase 0.0061 0.0124 0.0781
Schistosoma mansoni protein kinase 0.0052 0.0097 0.0095
Brugia malayi Voltage-gated potassium channel, HERG (KCNH2)-related. C. elegans unc-103 ortholog 0.0039 0.0055 0.0054
Trichomonas vaginalis AGC family protein kinase 0.0061 0.0124 0.0781
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0043 0.0069 0.0081
Loa Loa (eye worm) hypothetical protein 0.0115 0.0294 0.0294
Trichomonas vaginalis TKL family protein kinase 0.0052 0.0097 0.061
Echinococcus granulosus natriuretic peptide receptor 1 0.0052 0.0097 0.0114
Entamoeba histolytica protein kinase domain containing protein 0.0052 0.0097 0.061
Echinococcus multilocularis retinal guanylyl cyclase 2 0.0052 0.0097 0.0114
Trichomonas vaginalis TKL family protein kinase 0.0052 0.0097 0.061
Loa Loa (eye worm) hypothetical protein 0.0029 0.0023 0.0023
Trichomonas vaginalis AGC family protein kinase 0.0061 0.0124 0.0781
Entamoeba histolytica protein kinase, putative 0.0072 0.016 0.1013
Loa Loa (eye worm) hypothetical protein 0.0048 0.0083 0.0083
Echinococcus granulosus atrial natriuretic peptide receptor 1 0.0052 0.0097 0.0114
Echinococcus granulosus tyrosine protein kinase csk 0.0052 0.0097 0.0114
Trichomonas vaginalis TKL family protein kinase 0.0052 0.0097 0.061
Entamoeba histolytica protein kinase, putative 0.0061 0.0124 0.0781
Echinococcus multilocularis protein patched 0.0051 0.0093 0.0109
Echinococcus multilocularis DCC interacting protein 13 beta 0.0048 0.0083 0.0097
Entamoeba histolytica serine/threonine protein kinase 6, putative 0.0072 0.016 0.1013
Echinococcus granulosus tyrosine protein kinase ABL1 0.0052 0.0097 0.0114
Toxoplasma gondii phosphatidylinositol transfer protein 0.0048 0.0083 0.5138
Echinococcus multilocularis tyrosine protein kinase Fgr 0.0052 0.0097 0.0114
Brugia malayi Protein kinase domain containing protein 0.0052 0.0097 0.0095
Trichomonas vaginalis conserved hypothetical protein 0.0521 0.1565 1
Loa Loa (eye worm) hypothetical protein 0.0147 0.0394 0.0394
Onchocerca volvulus 0.0052 0.0097 0.032
Trichomonas vaginalis TKL family protein kinase 0.0052 0.0097 0.061
Brugia malayi PH domain containing protein 0.0048 0.0083 0.0081
Loa Loa (eye worm) TK protein kinase 0.0052 0.0097 0.0097

Activities

Activity type Activity value Assay description Source Reference
Potency (functional) 0.5012 uM PubChem BioAssay. qHTS for Activators of Integrin-Mediated Alleviation for Muscular Dystrophy. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) 1.1689 uM PUBCHEM_BIOASSAY: Primary qHTS for delayed death inhibitors of the malarial parasite plastid, 48 hour incubation. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID488752, AID488774, AID504848, AID504850] ChEMBL. No reference
Potency (functional) 1.2589 uM PubChem BioAssay. qHTS of GLP-1 Receptor Inverse Agonists (Inhibition Mode). (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) = 1.7783 um PUBCHEM_BIOASSAY: qHTS Assay for NPC1 Promoter Activators. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) = 2.5119 um PUBCHEM_BIOASSAY: qHTS Assay for Small Molecule Inhibitors of Mitochondrial Division or Activators of Mitochondrial Fusion. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) 2.6169 uM PUBCHEM_BIOASSAY: Primary qHTS for delayed death inhibitors of the malarial parasite plastid, 96 hour incubation. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID488745, AID488752, AID488774, AID504848, AID504850] ChEMBL. No reference
Potency (functional) = 2.8184 um PUBCHEM_BIOASSAY: qHTS Assay for Rab9 Promoter Activators. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) = 3.5481 um PUBCHEM_BIOASSAY: qHTS Assay for Identifying a Potential Treatment of Ataxia-Telangiectasia. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) 4.609 uM PUBCHEM_BIOASSAY: qHTS screen for small molecules that inhibit ELG1-dependent DNA repair in human embryonic kidney (HEK293T) cells expressing luciferase-tagged ELG1. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID493107, AID493125] ChEMBL. No reference
Potency (functional) 5.1735 uM PUBCHEM_BIOASSAY: Nrf2 qHTS screen for inhibitors. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID493153, AID493163, AID504648] ChEMBL. No reference
Potency (functional) 6.7456 uM PUBCHEM_BIOASSAY: qHTS profiling assay for firefly luciferase inhibitor/activator using purified enzyme and Km concentrations of substrates (counterscreen for miR-21 project). (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID2288, AID2289, AID2598, AID411] ChEMBL. No reference
Potency (functional) 9.1962 uM PUBCHEM_BIOASSAY: qHTS screen for small molecules that induce genotoxicity in human embryonic kidney (HEK293T) cells expressing luciferase-tagged ELG1. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID493106, AID493143] ChEMBL. No reference
Potency (functional) 10 uM PUBCHEM_BIOASSAY: qHTS for Inhibitors of binding or entry into cells for Lassa Virus. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID463114, AID540249] ChEMBL. No reference
Potency (functional) 12.5893 uM PUBCHEM_BIOASSAY: qHTS for Inhibitors of TGF-b: Cytotox Counterscreen. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID588855, AID588860] ChEMBL. No reference
Potency (functional) = 14.1254 um PUBCHEM_BIOASSAY: VP16 counterscreen qHTS for inhibitors of ROR gamma transcriptional activity. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) = 14.1254 um PUBCHEM_BIOASSAY: qHTS Assay for Inhibitors of Influenza NS1 Protein Function. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) = 25.1189 um PUBCHEM_BIOASSAY: qHTS for inhibitors of ROR gamma transcriptional activity. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) 25.1189 uM PUBCHEM_BIOASSAY: qHTS Assay for Inhibitors of JMJD2A-Tudor Domain. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID504402] ChEMBL. No reference
Potency (functional) 29.9349 uM PubChem BioAssay. qHTS for Inhibitors of PLK1-PDB (polo-like kinase 1 - polo-box domain): Primary Screen. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) 39.8107 uM PubChem BioAssay. qHTS of PTHR Inhibitors: Primary Screen. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) 50.1187 uM PUBCHEM_BIOASSAY: qHTS assay for re-activators of p53 using a Luc reporter. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID504709] ChEMBL. No reference
Potency (functional) 50.1187 uM PUBCHEM_BIOASSAY: Inhibitors of Regulator of G Protein Signaling (RGS) 4: qHTS. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID504856] ChEMBL. No reference
Potency (functional) 70.7946 uM PUBCHEM_BIOASSAY: Inhibitors of the vitamin D receptor (VDR): qHTS. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID504855] ChEMBL. No reference
Potency (functional) 89.1251 uM PUBCHEM_BIOASSAY: qHTS for Inhibitors of Polymerase Iota. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID588623] ChEMBL. No reference

Phenotypes

Whole-cell/tissue/organism interactions

Species name Source Reference Is orphan
Saccharomyces cerevisiae ChEMBL23
Homo sapiens ChEMBL23
Plasmodium falciparum ChEMBL23

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

Bibliographic References

No literature references available for this target.

If you have references for this compound, please enter them in a user comment (below) or Contact us.