Detailed information for compound 1389305

Basic information

Technical information
  • TDR Targets ID: 1389305
  • Name: 2-[3-(2-hydroxyethoxy)quinoxalin-2-yl]-2-(4-m ethylphenyl)sulfonylacetonitrile
  • MW: 383.421 | Formula: C19H17N3O4S
  • H donors: 1 H acceptors: 6 LogP: 1.95 Rotable bonds: 6
    Rule of 5 violations (Lipinski): 1
  • SMILES: OCCOc1nc2ccccc2nc1C(S(=O)(=O)c1ccc(cc1)C)C#N
  • InChi: 1S/C19H17N3O4S/c1-13-6-8-14(9-7-13)27(24,25)17(12-20)18-19(26-11-10-23)22-16-5-3-2-4-15(16)21-18/h2-9,17,23H,10-11H2,1H3
  • InChiKey: PIAOOFXGNRYVIL-UHFFFAOYSA-N  


Substructure search Similarity search

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Synonyms

  • 2-[3-(2-hydroxyethoxy)quinoxalin-2-yl]-2-(4-methylphenyl)sulfonyl-acetonitrile
  • 2-[3-(2-hydroxyethoxy)-2-quinoxalinyl]-2-(4-methylphenyl)sulfonylacetonitrile
  • 2-[3-(2-hydroxyethoxy)quinoxalin-2-yl]-2-(4-methylphenyl)sulfonyl-ethanenitrile
  • MLS001011167
  • SMR000353161
  • Oprea1_309268

Targets

Known targets for this compound

Species Target name Source Bibliographic reference
Mus musculus RAR-related orphan receptor gamma Starlite/ChEMBL No references
Photinus pyralis Luciferin 4-monooxygenase Starlite/ChEMBL No references
Homo sapiens geminin, DNA replication inhibitor Starlite/ChEMBL No references
Homo sapiens snurportin 1 No references
Homo sapiens karyopherin (importin) beta 1 No references
Homo sapiens RAN, member RAS oncogene family No references
Homo sapiens parathyroid hormone 1 receptor Starlite/ChEMBL No references
Homo sapiens GNAS complex locus Starlite/ChEMBL No references

Predicted pathogen targets for this compound

By orthology
Species Potential target Known druggable target/s Ortholog Group
Mycobacterium ulcerans hypothetical protein Get druggable targets OG5_126609 All targets in OG5_126609
Schistosoma japonicum Importin subunit beta-1, putative Get druggable targets OG5_127843 All targets in OG5_127843
Cryptosporidium parvum GTP-binding nuclear protein ran/tc4 Get druggable targets OG5_127514 All targets in OG5_127514
Leishmania braziliensis 4-coumarate:coa ligase-like protein Get druggable targets OG5_126609 All targets in OG5_126609
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative Get druggable targets OG5_131088 All targets in OG5_131088
Entamoeba histolytica hypothetical protein Get druggable targets OG5_127843 All targets in OG5_127843
Candida albicans karyopherin-beta Get druggable targets OG5_127843 All targets in OG5_127843
Leishmania infantum importin beta-1 subunit, putative Get druggable targets OG5_127843 All targets in OG5_127843
Trichomonas vaginalis Importin beta-1 subunit, putative Get druggable targets OG5_127843 All targets in OG5_127843
Trypanosoma brucei importin beta-1 subunit, putative Get druggable targets OG5_127843 All targets in OG5_127843
Trypanosoma brucei importin beta-1 subunit, putative Get druggable targets OG5_127843 All targets in OG5_127843
Toxoplasma gondii HEAT repeat-containing protein Get druggable targets OG5_127843 All targets in OG5_127843
Entamoeba histolytica Ran family GTPase Get druggable targets OG5_127514 All targets in OG5_127514
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_126609 All targets in OG5_126609
Mycobacterium ulcerans fatty-acid-CoA ligase Get druggable targets OG5_126609 All targets in OG5_126609
Mycobacterium ulcerans acyl-CoA synthetase Get druggable targets OG5_126609 All targets in OG5_126609
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_127843 All targets in OG5_127843
Trypanosoma brucei GTP-binding nuclear protein rtb2, putative Get druggable targets OG5_127514 All targets in OG5_127514
Cryptosporidium hominis GTP-binding nuclear protein ran/tc4 Get druggable targets OG5_127514 All targets in OG5_127514
Leishmania donovani GTP-binding protein, putative Get druggable targets OG5_127514 All targets in OG5_127514
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain Get druggable targets OG5_131088 All targets in OG5_131088
Brugia malayi AMP-binding enzyme family protein Get druggable targets OG5_126609 All targets in OG5_126609
Trypanosoma brucei gambiense importin beta-1 subunit, putative Get druggable targets OG5_127843 All targets in OG5_127843
Loa Loa (eye worm) nucleolar RNA-associated protein alpha Get druggable targets OG5_131808 All targets in OG5_131808
Plasmodium falciparum GTP-binding nuclear protein RAN/TC4 Get druggable targets OG5_127514 All targets in OG5_127514
Plasmodium yoelii GTP-binding nuclear protein ran/tc4 Get druggable targets OG5_127514 All targets in OG5_127514
Leishmania mexicana GTP-binding protein, putative Get druggable targets OG5_127514 All targets in OG5_127514
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit Get druggable targets OG5_131088 All targets in OG5_131088
Candida albicans Ran, Ras family GTP-binding protein Get druggable targets OG5_127514 All targets in OG5_127514
Plasmodium yoelii peroxisomal-coenzyme a synthetase Get druggable targets OG5_126609 All targets in OG5_126609
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD3 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) Get druggable targets OG5_126609 All targets in OG5_126609
Echinococcus multilocularis snurportin 1 Get druggable targets OG5_131808 All targets in OG5_131808
Echinococcus granulosus guanine nucleotide binding protein Gs subunit Get druggable targets OG5_131088 All targets in OG5_131088
Leishmania major 4-coumarate:coa ligase-like protein Get druggable targets OG5_126609 All targets in OG5_126609
Leishmania mexicana importin beta-1 subunit, putative Get druggable targets OG5_127843 All targets in OG5_127843
Mycobacterium ulcerans long-chain fatty-acid CoA ligase Get druggable targets OG5_126609 All targets in OG5_126609
Brugia malayi AMP-binding enzyme family protein Get druggable targets OG5_126609 All targets in OG5_126609
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD7 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) Get druggable targets OG5_126609 All targets in OG5_126609
Chlamydia trachomatis acylglycerophosphoethanolamine acyltransferase Get druggable targets OG5_126609 All targets in OG5_126609
Plasmodium knowlesi GTP-binding nuclear protein RAN/TC4, putative Get druggable targets OG5_127514 All targets in OG5_127514
Plasmodium berghei acyl-CoA synthetase, putative Get druggable targets OG5_126609 All targets in OG5_126609
Schistosoma japonicum ko:K04632 guanine nucleotide binding protein (G protein), alpha stimulating, putative Get druggable targets OG5_131088 All targets in OG5_131088
Entamoeba histolytica acyl-coA synthetase, putative Get druggable targets OG5_126609 All targets in OG5_126609
Echinococcus granulosus GTP binding nuclear protein Ran Get druggable targets OG5_127514 All targets in OG5_127514
Entamoeba histolytica acyl-CoA synthetase, putative Get druggable targets OG5_126609 All targets in OG5_126609
Trypanosoma brucei gambiense GTP-binding nuclear protein rtb2, putative Get druggable targets OG5_127514 All targets in OG5_127514
Leishmania donovani importin beta-1 subunit, putative Get druggable targets OG5_127843 All targets in OG5_127843
Theileria parva GTP-binding nuclear protein ran, putative Get druggable targets OG5_127514 All targets in OG5_127514
Schistosoma japonicum Snurportin-1, putative Get druggable targets OG5_131808 All targets in OG5_131808
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) Get druggable targets OG5_131088 All targets in OG5_131088
Schistosoma mansoni ran Get druggable targets OG5_127514 All targets in OG5_127514
Trypanosoma congolense GTP-binding nuclear protein rtb2, putative Get druggable targets OG5_127514 All targets in OG5_127514
Leishmania major 4-coumarate:coa ligase-like protein Get druggable targets OG5_126609 All targets in OG5_126609
Schistosoma japonicum ko:K07936 GTP-binding nuclear protein Ran, putative Get druggable targets OG5_127514 All targets in OG5_127514
Leishmania braziliensis importin beta-1 subunit, putative Get druggable targets OG5_127843 All targets in OG5_127843
Echinococcus granulosus importin subunit beta 1 Get druggable targets OG5_127843 All targets in OG5_127843
Babesia bovis GTP-binding nuclear protein Ran Get druggable targets OG5_127514 All targets in OG5_127514
Trichomonas vaginalis Importin beta-1 subunit, putative Get druggable targets OG5_127843 All targets in OG5_127843
Schistosoma mansoni ran Get druggable targets OG5_127514 All targets in OG5_127514
Echinococcus multilocularis importin subunit beta 1 Get druggable targets OG5_127843 All targets in OG5_127843
Plasmodium vivax acyl-CoA synthetase, putative Get druggable targets OG5_126609 All targets in OG5_126609
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD7 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) Get druggable targets OG5_126609 All targets in OG5_126609
Neospora caninum hypothetical protein Get druggable targets OG5_127843 All targets in OG5_127843
Giardia lamblia GTP-binding nuclear protein RAN/TC4 Get druggable targets OG5_127514 All targets in OG5_127514
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) Get druggable targets OG5_131088 All targets in OG5_131088
Schistosoma mansoni importin beta-1 Get druggable targets OG5_127843 All targets in OG5_127843
Schistosoma japonicum ko:K04588 secretin receptor, putative Get druggable targets OG5_139196 All targets in OG5_139196
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_126609 All targets in OG5_126609
Mycobacterium tuberculosis Probable chain -fatty-acid-CoA ligase FadD13 (fatty-acyl-CoA synthetase) Get druggable targets OG5_126609 All targets in OG5_126609
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_126609 All targets in OG5_126609
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative Get druggable targets OG5_127514 All targets in OG5_127514
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative Get druggable targets OG5_127514 All targets in OG5_127514
Trypanosoma congolense importin beta-1 subunit, putative Get druggable targets OG5_127843 All targets in OG5_127843
Echinococcus multilocularis GTP binding nuclear protein Ran Get druggable targets OG5_127514 All targets in OG5_127514
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit Get druggable targets OG5_131088 All targets in OG5_131088
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) Get druggable targets OG5_131088 All targets in OG5_131088
Leishmania infantum 4-coumarate:coa ligase-like protein Get druggable targets OG5_126609 All targets in OG5_126609
Leishmania major GTP-binding protein, putative Get druggable targets OG5_127514 All targets in OG5_127514
Candida albicans Ran, Ras family GTP-binding protein Get druggable targets OG5_127514 All targets in OG5_127514
Trypanosoma cruzi importin beta-1 subunit, putative Get druggable targets OG5_127843 All targets in OG5_127843
Schistosoma japonicum Importin subunit beta, putative Get druggable targets OG5_127843 All targets in OG5_127843
Echinococcus granulosus snurportin 1 Get druggable targets OG5_131808 All targets in OG5_131808
Mycobacterium ulcerans long-chain-fatty-acid--CoA ligase Get druggable targets OG5_126609 All targets in OG5_126609
Theileria parva importin beta, putative Get druggable targets OG5_127843 All targets in OG5_127843
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD2 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) Get druggable targets OG5_126609 All targets in OG5_126609
Brugia malayi GTP-binding nuclear protein RAN/TC4 Get druggable targets OG5_127514 All targets in OG5_127514
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD2 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) Get druggable targets OG5_126609 All targets in OG5_126609
Leishmania donovani 4-coumarate:coa ligase-like protein Get druggable targets OG5_126609 All targets in OG5_126609
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_126609 All targets in OG5_126609
Echinococcus granulosus guanine nucleotide binding protein Gs subunit Get druggable targets OG5_131088 All targets in OG5_131088
Brugia malayi AMP-binding enzyme family protein Get druggable targets OG5_126609 All targets in OG5_126609
Leishmania mexicana 4-coumarate:coa ligase-like protein Get druggable targets OG5_126609 All targets in OG5_126609
Onchocerca volvulus Get druggable targets OG5_126609 All targets in OG5_126609
Leishmania major importin beta-1 subunit, putative Get druggable targets OG5_127843 All targets in OG5_127843
Babesia bovis importin beta subunit, putative Get druggable targets OG5_127843 All targets in OG5_127843
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_126609 All targets in OG5_126609
Plasmodium knowlesi importin beta, putative Get druggable targets OG5_127843 All targets in OG5_127843
Cryptosporidium hominis importin-beta2 Get druggable targets OG5_127843 All targets in OG5_127843
Leishmania infantum 4-coumarate:coa ligase-like protein Get druggable targets OG5_126609 All targets in OG5_126609
Loa Loa (eye worm) GTP-binding nuclear protein RAN/TC4 Get druggable targets OG5_127514 All targets in OG5_127514
Mycobacterium ulcerans acyl-CoA synthetase Get druggable targets OG5_126609 All targets in OG5_126609
Plasmodium berghei importin beta, putative Get druggable targets OG5_127843 All targets in OG5_127843
Cryptosporidium parvum importin/karyopherin Get druggable targets OG5_127843 All targets in OG5_127843
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD5 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) Get druggable targets OG5_126609 All targets in OG5_126609
Plasmodium vivax importin-beta 2, putative Get druggable targets OG5_127843 All targets in OG5_127843
Plasmodium yoelii importin beta-1 subunit Get druggable targets OG5_127843 All targets in OG5_127843
Toxoplasma gondii GTP-binding nuclear protein ran/tc4 Get druggable targets OG5_127514 All targets in OG5_127514
Mycobacterium ulcerans acyl-CoA synthetase Get druggable targets OG5_126609 All targets in OG5_126609
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_126609 All targets in OG5_126609
Schistosoma mansoni hypothetical protein Get druggable targets OG5_131808 All targets in OG5_131808
Leishmania braziliensis GTP-binding protein, putative Get druggable targets OG5_127514 All targets in OG5_127514
Plasmodium falciparum importin beta, putative Get druggable targets OG5_127843 All targets in OG5_127843
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD35 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) Get druggable targets OG5_126609 All targets in OG5_126609
Trichomonas vaginalis importin beta-1, putative Get druggable targets OG5_127843 All targets in OG5_127843
Leishmania donovani 4-coumarate:coa ligase-like protein Get druggable targets OG5_126609 All targets in OG5_126609
Leishmania mexicana 4-coumarate:coa ligase-like protein Get druggable targets OG5_126609 All targets in OG5_126609
Leishmania mexicana 4-coumarate:coa ligase-like protein Get druggable targets OG5_126609 All targets in OG5_126609
Mycobacterium ulcerans long-chain-fatty-acid-CoA ligase Get druggable targets OG5_126609 All targets in OG5_126609
Plasmodium vivax GTP-binding nuclear protein RAN/TC4, putative Get druggable targets OG5_127514 All targets in OG5_127514
Leishmania infantum 4-coumarate:coa ligase-like protein Get druggable targets OG5_126609 All targets in OG5_126609
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_126609 All targets in OG5_126609
Plasmodium falciparum acyl-CoA synthetase Get druggable targets OG5_126609 All targets in OG5_126609
Leishmania infantum GTP-binding protein, putative Get druggable targets OG5_127514 All targets in OG5_127514
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_126609 All targets in OG5_126609
Plasmodium knowlesi acyl-CoA synthetase, putative Get druggable targets OG5_126609 All targets in OG5_126609
Mycobacterium ulcerans fatty-acid-CoA ligase Get druggable targets OG5_126609 All targets in OG5_126609
Mycobacterium tuberculosis Fatty-acid-AMP ligase FadD30 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) Get druggable targets OG5_126609 All targets in OG5_126609
Neospora caninum GTP-binding nuclear protein Ran, related Get druggable targets OG5_127514 All targets in OG5_127514
Candida albicans karyopherin-beta Get druggable targets OG5_127843 All targets in OG5_127843
Leishmania infantum 4-coumarate:coa ligase-like protein Get druggable targets OG5_126609 All targets in OG5_126609
Brugia malayi RNA, U transporter 1 Get druggable targets OG5_131808 All targets in OG5_131808
Leishmania major 4-coumarate:coa ligase-like protein Get druggable targets OG5_126609 All targets in OG5_126609
Trichomonas vaginalis ran, putative Get druggable targets OG5_127514 All targets in OG5_127514
Entamoeba histolytica acyl-CoA synthetase, putative Get druggable targets OG5_126609 All targets in OG5_126609
Plasmodium berghei GTP-binding nuclear protein RAN/TC4, putative Get druggable targets OG5_127514 All targets in OG5_127514
Brugia malayi Importin beta-1 subunit Get druggable targets OG5_127843 All targets in OG5_127843
By sequence similarity to non orthologous known druggable targets
Species Potential target Known druggable target Length Alignment span Identity
Dictyostelium discoideum hypothetical protein Luciferin 4-monooxygenase   550 aa 538 aa 21.8 %
Mycobacterium ulcerans peptide synthetase Nrp (peptide synthase) Luciferin 4-monooxygenase   550 aa 535 aa 23.2 %
Trichomonas vaginalis AMP dependent CoA ligase, putative Luciferin 4-monooxygenase   550 aa 524 aa 24.0 %
Leishmania braziliensis long chain fatty Acyl CoA synthetase, putative Luciferin 4-monooxygenase   550 aa 496 aa 22.8 %
Toxoplasma gondii propionate-CoA ligase Luciferin 4-monooxygenase   550 aa 550 aa 21.1 %
Mycobacterium leprae FATTY-ACID-CoA LIGASE FADD26 (FATTY-ACID-COA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) Luciferin 4-monooxygenase   550 aa 533 aa 22.7 %
Dictyostelium discoideum fatty acyl-CoA synthetase Luciferin 4-monooxygenase   550 aa 462 aa 23.8 %
Entamoeba histolytica acyl-CoA synthetase, putative Luciferin 4-monooxygenase   550 aa 446 aa 22.0 %
Brugia malayi Hypothetical 65.5 kDa Trp-Asp repeats containing protein F02E8.5 inchromosome X geminin, DNA replication inhibitor 209 aa 176 aa 27.8 %
Candida albicans similar to S. cerevisiae FAA4 (YMR246W) long-chain fatty acid--CoA synthetase Luciferin 4-monooxygenase   550 aa 478 aa 23.4 %
Mycobacterium leprae PROBABLE FATTY-ACID--CoA LIGASE FADD21 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) Luciferin 4-monooxygenase   550 aa 565 aa 22.8 %
Dictyostelium discoideum hypothetical protein Luciferin 4-monooxygenase   550 aa 539 aa 19.1 %
Trichomonas vaginalis AMP dependent ligase/synthetase, putative Luciferin 4-monooxygenase   550 aa 526 aa 22.4 %
Leishmania donovani long chain fatty Acyl CoA synthetase, putative Luciferin 4-monooxygenase   550 aa 500 aa 23.4 %
Trichomonas vaginalis AMP dependent ligase/synthetase, putative Luciferin 4-monooxygenase   550 aa 554 aa 24.4 %
Dictyostelium discoideum hypothetical protein Luciferin 4-monooxygenase   550 aa 522 aa 19.9 %
Trichomonas vaginalis AMP dependent ligase/synthetase, putative Luciferin 4-monooxygenase   550 aa 494 aa 24.3 %
Dictyostelium discoideum hypothetical protein Luciferin 4-monooxygenase   550 aa 542 aa 18.3 %
Dictyostelium discoideum hypothetical protein Luciferin 4-monooxygenase   550 aa 507 aa 20.9 %
Dictyostelium discoideum AMP-dependent synthetase and ligase domain-containing protein Luciferin 4-monooxygenase   550 aa 545 aa 24.9 %
Leishmania infantum long chain fatty Acyl CoA synthetase, putative Luciferin 4-monooxygenase   550 aa 500 aa 23.4 %
Mycobacterium ulcerans non-ribosomal peptide synthetase MbtE Luciferin 4-monooxygenase   550 aa 502 aa 22.5 %
Schistosoma japonicum ko:K08745 solute carrier family 27 (fatty acid transporter), member 1, putative Luciferin 4-monooxygenase   550 aa 501 aa 24.6 %
Trichomonas vaginalis antibiotic synthetase, putative Luciferin 4-monooxygenase   550 aa 581 aa 21.2 %
Mycobacterium tuberculosis Bifunctional enzyme MbtA: salicyl-AMP ligase (SAL-AMP ligase) + salicyl-S-ArCP synthetase Luciferin 4-monooxygenase   550 aa 536 aa 24.4 %
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD34 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) Luciferin 4-monooxygenase   550 aa 537 aa 20.9 %
Candida albicans similar to S. cerevisiae ACS2 (YLR153C) acetyl-CoA synthetase Luciferin 4-monooxygenase   550 aa 539 aa 22.1 %
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein Luciferin 4-monooxygenase   550 aa 476 aa 22.5 %
Dictyostelium discoideum hypothetical protein Luciferin 4-monooxygenase   550 aa 541 aa 21.6 %
Dictyostelium discoideum hypothetical protein Luciferin 4-monooxygenase   550 aa 542 aa 22.1 %
Dictyostelium discoideum hypothetical protein Luciferin 4-monooxygenase   550 aa 535 aa 22.6 %
Mycobacterium tuberculosis Probable fatty-acid-AMP ligase FadD23 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) Luciferin 4-monooxygenase   550 aa 542 aa 23.8 %
Echinococcus granulosus long chain fatty acid coenzyme A ligase 5 Luciferin 4-monooxygenase   550 aa 458 aa 25.8 %
Mycobacterium leprae Probable fatty-acid-CoA synthetase FadD32 (fatty-acid-CoA ligase) (fatty-acid-CoA synthase) Luciferin 4-monooxygenase   550 aa 442 aa 23.5 %
Dictyostelium discoideum hypothetical protein Luciferin 4-monooxygenase   550 aa 535 aa 21.7 %
Dictyostelium discoideum hypothetical protein Luciferin 4-monooxygenase   550 aa 539 aa 19.1 %
Echinococcus granulosus long chain fatty acid coenzyme A ligase 1 Luciferin 4-monooxygenase   550 aa 452 aa 26.1 %
Schistosoma japonicum ko:K01897 long-chain fatty-acid-CoA ligase [EC6.2.1.3], putative Luciferin 4-monooxygenase   550 aa 466 aa 27.3 %
Dictyostelium discoideum hypothetical protein Luciferin 4-monooxygenase   550 aa 541 aa 21.6 %
Trypanosoma congolense fatty acyl CoA synthetase 2, putative Luciferin 4-monooxygenase   550 aa 500 aa 22.4 %
Mycobacterium tuberculosis Probable fatty-acid-AMP ligase FadD24 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) Luciferin 4-monooxygenase   550 aa 526 aa 21.9 %
Trichomonas vaginalis AMP dependent ligase/synthetase, putative Luciferin 4-monooxygenase   550 aa 554 aa 22.9 %
Cryptosporidium hominis acetyl-CoenzymeA synthetase (acetate--coa ligase) (acyl-activating enzyme) Luciferin 4-monooxygenase   550 aa 549 aa 22.6 %
Cryptosporidium parvum putative long chain fatty acyl CoA synthetase having a signal peptide Luciferin 4-monooxygenase   550 aa 472 aa 24.8 %
Dictyostelium discoideum hypothetical protein Luciferin 4-monooxygenase   550 aa 558 aa 20.4 %
Mycobacterium leprae Probable fatty-acid-CoA synthetase FadD22 (fatty-acid-CoA ligase) (fatty-acid-CoA synthase) Luciferin 4-monooxygenase   550 aa 493 aa 20.7 %
Mycobacterium ulcerans long-chain-fatty-acid-CoA ligase, FadD11 Luciferin 4-monooxygenase   550 aa 492 aa 24.6 %
Entamoeba histolytica long-chain-fatty-acid--CoA ligase, putative Luciferin 4-monooxygenase   550 aa 480 aa 21.5 %
Cryptosporidium parvum acetyl-coenzyme A synthetase Luciferin 4-monooxygenase   550 aa 545 aa 22.8 %
Dictyostelium discoideum hypothetical protein Luciferin 4-monooxygenase   550 aa 576 aa 19.8 %
Mycobacterium ulcerans fatty-acid-CoA ligase FadD11 Luciferin 4-monooxygenase   550 aa 498 aa 23.5 %
Cryptosporidium hominis acyl-CoA synthetase Luciferin 4-monooxygenase   550 aa 460 aa 26.1 %
Brugia malayi AMP-binding enzyme family protein Luciferin 4-monooxygenase   550 aa 544 aa 21.5 %
Trichomonas vaginalis AMP dependent CoA ligase, putative Luciferin 4-monooxygenase   550 aa 527 aa 25.0 %
Mycobacterium leprae Probable fatty-acid-CoA synthetase FadD28 (fatty-acid-CoA ligase) (fatty-acid-CoA synthase) Luciferin 4-monooxygenase   550 aa 484 aa 20.5 %
Babesia bovis fatty acyl-CoA synthetase family protein Luciferin 4-monooxygenase   550 aa 461 aa 23.4 %
Echinococcus multilocularis long chain fatty acid transport protein 4 Luciferin 4-monooxygenase   550 aa 476 aa 22.3 %
Leishmania major long chain fatty Acyl CoA synthetase, putative Luciferin 4-monooxygenase   550 aa 482 aa 23.2 %
Dictyostelium discoideum hypothetical protein Luciferin 4-monooxygenase   550 aa 499 aa 19.2 %
Neospora caninum acetyl-coenzyme a synthetase, putative Luciferin 4-monooxygenase   550 aa 549 aa 20.9 %
Dictyostelium discoideum AMP-dependent synthetase and ligase domain-containing protein Luciferin 4-monooxygenase   550 aa 550 aa 20.9 %
Leishmania braziliensis acetyl-CoA synthetase, putative Luciferin 4-monooxygenase   550 aa 596 aa 21.1 %
Schistosoma japonicum ko:K01897 long-chain fatty-acid-CoA ligase [EC6.2.1.3], putative Luciferin 4-monooxygenase   550 aa 541 aa 22.4 %
Mycobacterium ulcerans non-ribosomal peptide synthetase Luciferin 4-monooxygenase   550 aa 541 aa 22.4 %
Trichomonas vaginalis AMP dependent CoA ligase, putative Luciferin 4-monooxygenase   550 aa 492 aa 23.6 %
Dictyostelium discoideum acetyl-CoA ligase Luciferin 4-monooxygenase   550 aa 549 aa 22.2 %
Mycobacterium leprae Probable long-chain-fatty-acid-CoA ligase FadD15 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) Luciferin 4-monooxygenase   550 aa 484 aa 23.3 %
Echinococcus granulosus long chain fatty acid transport protein 4 Luciferin 4-monooxygenase   550 aa 476 aa 22.3 %
Onchocerca volvulus Lysine-specific histone demethylase 1A homolog Luciferin 4-monooxygenase   550 aa 550 aa 22.5 %
Onchocerca volvulus Matrilysin homolog Luciferin 4-monooxygenase   550 aa 466 aa 24.2 %
Schistosoma mansoni FAA1 Long-chain-fatty-acid--CoA ligase 1 Luciferin 4-monooxygenase   550 aa 494 aa 26.3 %
Echinococcus multilocularis long chain fatty acid coenzyme A ligase 1 Luciferin 4-monooxygenase   550 aa 459 aa 27.0 %
Trypanosoma brucei fatty acyl CoA synthetase 3 Luciferin 4-monooxygenase   550 aa 491 aa 23.6 %
Mycobacterium tuberculosis Fatty-acid-AMP ligase FadD29 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) Luciferin 4-monooxygenase   550 aa 617 aa 22.2 %
Dictyostelium discoideum hypothetical protein Luciferin 4-monooxygenase   550 aa 478 aa 21.1 %
Candida albicans similar to S. cerevisiae ACS2 (YLR153C) acetyl-CoA synthetase Luciferin 4-monooxygenase   550 aa 539 aa 22.1 %
Trypanosoma cruzi fatty acyl CoA synthetase, putative Luciferin 4-monooxygenase   550 aa 480 aa 25.2 %
Trichomonas vaginalis AMP dependent ligase, putative Luciferin 4-monooxygenase   550 aa 445 aa 26.1 %
Dictyostelium discoideum hypothetical protein Luciferin 4-monooxygenase   550 aa 542 aa 22.1 %
Leishmania mexicana acetyl-CoA synthetase, putative Luciferin 4-monooxygenase   550 aa 559 aa 20.6 %
Mycobacterium tuberculosis Fatty-acid-AMP ligase FadD28 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) Luciferin 4-monooxygenase   550 aa 504 aa 22.6 %
Dictyostelium discoideum hypothetical protein Luciferin 4-monooxygenase   550 aa 541 aa 21.4 %
Echinococcus multilocularis long chain fatty acid coenzyme A ligase 5 Luciferin 4-monooxygenase   550 aa 458 aa 25.5 %
Mycobacterium leprae Probable fatty-acid-CoA synthetase FadD29 (fatty-acid-CoA ligase) (fatty-acid-CoA synthase) Luciferin 4-monooxygenase   550 aa 529 aa 22.3 %
Mycobacterium ulcerans acyl-CoA synthetase Luciferin 4-monooxygenase   550 aa 530 aa 23.8 %
Mycobacterium tuberculosis Probable fatty-acid-AMP ligase FadD21 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) Luciferin 4-monooxygenase   550 aa 586 aa 24.4 %
Dictyostelium discoideum hypothetical protein Luciferin 4-monooxygenase   550 aa 542 aa 18.3 %
Trypanosoma brucei gambiense fatty acyl CoA synthetase 4, putative Luciferin 4-monooxygenase   550 aa 497 aa 23.7 %
Mycobacterium tuberculosis Probable acyl-CoA ligase FadD31 (acyl-CoA synthetase) (acyl-CoA synthase) Luciferin 4-monooxygenase   550 aa 592 aa 20.4 %
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD8 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) Luciferin 4-monooxygenase   550 aa 505 aa 28.1 %
Leishmania mexicana long chain fatty Acyl CoA synthetase, putative Luciferin 4-monooxygenase   550 aa 483 aa 23.8 %
Dictyostelium discoideum fatty acyl-CoA synthetase Luciferin 4-monooxygenase   550 aa 501 aa 24.4 %
Mycobacterium ulcerans acyl-CoA synthetase Luciferin 4-monooxygenase   550 aa 582 aa 22.3 %
Cryptosporidium parvum acyl-CoA synthetase Luciferin 4-monooxygenase   550 aa 460 aa 25.7 %
Trichomonas vaginalis AMP dependent ligase/synthetase, putative Luciferin 4-monooxygenase   550 aa 476 aa 23.5 %
Mycobacterium tuberculosis P-hydroxybenzoyl-AMP ligase FadD22 Luciferin 4-monooxygenase   550 aa 493 aa 22.1 %
Mycobacterium ulcerans acyl-CoA synthetase Luciferin 4-monooxygenase   550 aa 601 aa 22.5 %
Mycobacterium ulcerans long-chain-fatty-acid-CoA ligase FadD15 Luciferin 4-monooxygenase   550 aa 484 aa 26.0 %
Mycobacterium ulcerans long-chain-fatty-acid--CoA ligase Luciferin 4-monooxygenase   550 aa 509 aa 21.8 %
Leishmania braziliensis acetyl-CoA synthetase, putative Luciferin 4-monooxygenase   550 aa 603 aa 22.6 %
Brugia malayi AMP-binding enzyme family protein Luciferin 4-monooxygenase   550 aa 497 aa 24.7 %
Onchocerca volvulus Luciferin 4-monooxygenase   550 aa 502 aa 24.9 %
Dictyostelium discoideum AMP-dependent synthetase and ligase domain-containing protein Luciferin 4-monooxygenase   550 aa 517 aa 24.8 %
Candida albicans similar to S. cerevisiae FAT1 (YBR041W) fatty acid transporter and very long-chain fatty acyl-CoA synthetase Luciferin 4-monooxygenase   550 aa 496 aa 24.2 %
Candida albicans similar to S. cerevisiae ACS2 (YLR153C) acetyl-CoA synthetase Luciferin 4-monooxygenase   550 aa 543 aa 24.5 %
Echinococcus multilocularis long chain fatty acid coenzyme A ligase 1 Luciferin 4-monooxygenase   550 aa 443 aa 26.4 %
Onchocerca volvulus Luciferin 4-monooxygenase   550 aa 487 aa 23.8 %
Entamoeba histolytica long-chain-fatty-acid--CoA ligase, putative Luciferin 4-monooxygenase   550 aa 494 aa 23.9 %
Loa Loa (eye worm) AMP-binding enzyme family protein Luciferin 4-monooxygenase   550 aa 489 aa 23.3 %
Trichomonas vaginalis long-chain-fatty-acid CoA ligase, putative Luciferin 4-monooxygenase   550 aa 466 aa 21.7 %
Neospora caninum Short-chain dehydrogenase/reductase SDR, related Luciferin 4-monooxygenase   550 aa 518 aa 19.1 %
Mycobacterium tuberculosis Probable peptide synthetase Nrp (peptide synthase) Luciferin 4-monooxygenase   550 aa 509 aa 22.6 %
Toxoplasma gondii type I fatty acid synthase, putative Luciferin 4-monooxygenase   550 aa 514 aa 19.8 %
Theileria parva long-chain fatty acid CoA ligase, putative Luciferin 4-monooxygenase   550 aa 507 aa 23.5 %
Trypanosoma cruzi fatty acyl CoA synthetase, putative Luciferin 4-monooxygenase   550 aa 482 aa 24.7 %
Trypanosoma brucei gambiense fatty acyl CoA synthetase 3 Luciferin 4-monooxygenase   550 aa 491 aa 23.6 %
Mycobacterium ulcerans acyl-CoA synthetase Luciferin 4-monooxygenase   550 aa 593 aa 22.1 %
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD9 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) Luciferin 4-monooxygenase   550 aa 480 aa 22.5 %
Mycobacterium ulcerans acyl-CoA synthetase Luciferin 4-monooxygenase   550 aa 497 aa 19.3 %
Candida albicans similar to S. cerevisiae ACS2 (YLR153C) acetyl-CoA synthetase Luciferin 4-monooxygenase   550 aa 543 aa 24.5 %
Trypanosoma cruzi fatty acyl CoA synthetase 2, putative Luciferin 4-monooxygenase   550 aa 495 aa 22.6 %
Dictyostelium discoideum hypothetical protein Luciferin 4-monooxygenase   550 aa 463 aa 23.5 %
Mycobacterium tuberculosis Fatty-acid-AMP ligase FadD26 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) Luciferin 4-monooxygenase   550 aa 560 aa 21.4 %
Dictyostelium discoideum hypothetical protein Luciferin 4-monooxygenase   550 aa 541 aa 21.4 %
Mycobacterium tuberculosis Probable fatty-acid-AMP ligase FadD25 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) Luciferin 4-monooxygenase   550 aa 475 aa 21.1 %
Schistosoma mansoni GTP-binding protein alpha subunit gna GNAS complex locus 394 aa 450 aa 28.7 %
Entamoeba histolytica long-chain-fatty-acid--CoA ligase, putative Luciferin 4-monooxygenase   550 aa 476 aa 20.8 %
Dictyostelium discoideum hypothetical protein Luciferin 4-monooxygenase   550 aa 538 aa 21.8 %
Candida albicans similar to S. cerevisiae FAT1 (YBR041W) fatty acid transporter and very long-chain fatty acyl-CoA synthetase Luciferin 4-monooxygenase   550 aa 496 aa 24.2 %
Babesia bovis long-chain acyl-CoA synthetase, putative Luciferin 4-monooxygenase   550 aa 445 aa 21.8 %
Mycobacterium ulcerans long-chain-fatty-acid-CoA ligase FadD15 Luciferin 4-monooxygenase   550 aa 482 aa 24.3 %
Mycobacterium ulcerans putative fatty-acid--CoA ligase Luciferin 4-monooxygenase   550 aa 576 aa 20.8 %
Mycobacterium ulcerans fatty-acid-CoA ligase FadD9 Luciferin 4-monooxygenase   550 aa 463 aa 21.8 %
Mycobacterium ulcerans non-ribosomal peptide synthetase MbtF Luciferin 4-monooxygenase   550 aa 558 aa 20.1 %
Mycobacterium leprae Probable fatty-acid-CoA ligase FadD9 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) Luciferin 4-monooxygenase   550 aa 461 aa 22.3 %
Mycobacterium tuberculosis Fatty-acid-AMP ligase FadD32 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase). Also shown to have acyl-ACP ligase activity. Luciferin 4-monooxygenase   550 aa 487 aa 22.4 %
Dictyostelium discoideum AMP-dependent synthetase and ligase domain-containing protein Luciferin 4-monooxygenase   550 aa 531 aa 19.0 %
Trichomonas vaginalis antibiotic synthetase, putative Luciferin 4-monooxygenase   550 aa 577 aa 22.2 %
Trichomonas vaginalis long-chain-fatty-acid CoA ligase, putative Luciferin 4-monooxygenase   550 aa 490 aa 23.3 %
Dictyostelium discoideum hypothetical protein Luciferin 4-monooxygenase   550 aa 522 aa 19.9 %
Leishmania braziliensis long-chain-fatty-acid-CoA ligase, putative Luciferin 4-monooxygenase   550 aa 504 aa 25.6 %
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Brugia malayi hypothetical protein 0.0189 0.2013 0.2834
Schistosoma mansoni hypothetical protein 0.0139 0.1447 0.1698
Echinococcus granulosus tumor protein p63 0.0702 0.7801 0.8616
Brugia malayi Flap endonuclease-1 0.0029 0.02 0.0275
Schistosoma mansoni tensin 0.0013 0.0023 0.0019
Leishmania major glucose-6-phosphate 1-dehydrogenase, putative 0.0103 0.104 1
Loa Loa (eye worm) hypothetical protein 0.0013 0.0023 0.0032
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.0104 0.1051 0.3376
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0036 0.0287 0.0287
Brugia malayi MH2 domain containing protein 0.038 0.4168 0.5878
Mycobacterium ulcerans acyl-CoA synthetase 0.0029 0.0199 0.1103
Toxoplasma gondii flap structure-specific endonuclease 1, putative 0.0029 0.02 0.166
Schistosoma mansoni hypothetical protein 0.0022 0.0122 0.0136
Echinococcus multilocularis tyrosine protein kinase Blk 0.005 0.0441 0.0441
Echinococcus granulosus dnaJ subfamily B 0.0452 0.4982 0.5503
Echinococcus granulosus ecdysone induced protein 78C 0.0104 0.1051 0.1161
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0036 0.0287 0.0287
Echinococcus multilocularis Mitotic checkpoint protein PRCC, C terminal 0.0139 0.1447 0.1447
Echinococcus granulosus Nuclear hormone receptor HR96 0.0049 0.043 0.0475
Onchocerca volvulus 0.0013 0.0023 0.0053
Echinococcus multilocularis tyrosine protein kinase shark 0.0018 0.0078 0.0078
Echinococcus granulosus FTZ F1 alpha 0.0104 0.1051 0.1161
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.0104 0.1051 0.1161
Trypanosoma cruzi Phosphatidylinositol 3-kinase tor1 0.005 0.0436 0.4125
Loa Loa (eye worm) hypothetical protein 0.0012 0.0015 0.0022
Schistosoma mansoni rab6-interacting 0.0022 0.0122 0.0136
Mycobacterium tuberculosis Probable reductase 0.0119 0.1222 0.4341
Plasmodium falciparum GTP-binding nuclear protein RAN/TC4 0.0026 0.0165 0.1343
Brugia malayi PAS domain containing protein 0.018 0.1909 0.2687
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0104 0.1051 0.1476
Giardia lamblia Pyruvate kinase 0.0038 0.0303 0.2097
Trichomonas vaginalis conserved hypothetical protein 0.0042 0.0347 0.1173
Mycobacterium leprae PROBABLE ENDONUCLEASE IV END (ENDODEOXYRIBONUCLEASE IV) (APURINASE) 0.0085 0.0832 0.591
Plasmodium vivax glutathione reductase, putative 0.0052 0.0466 0.4006
Loa Loa (eye worm) hypothetical protein 0.0049 0.043 0.0607
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.0104 0.1051 0.1483
Loa Loa (eye worm) steroid hormone receptor 0.0104 0.1051 0.1483
Loa Loa (eye worm) nuclear hormone receptor 0.0049 0.043 0.0607
Loa Loa (eye worm) hypothetical protein 0.0014 0.0032 0.0045
Mycobacterium tuberculosis Probable soluble pyridine nucleotide transhydrogenase SthA (STH) (NAD(P)(+) transhydrogenase [B-specific]) (nicotinamide nucleot 0.0018 0.008 0.0103
Loa Loa (eye worm) hypothetical protein 0.0104 0.1051 0.1483
Trypanosoma cruzi cysteine peptidase, putative 0.0071 0.0672 0.6418
Onchocerca volvulus 0.0022 0.0122 0.0373
Trichomonas vaginalis PIKK family atypical protein kinase 0.0017 0.0064 0.0171
Brugia malayi hypothetical protein 0.0013 0.0023 0.0023
Schistosoma mansoni nuclear receptor nhr-48 0.0049 0.043 0.05
Loa Loa (eye worm) follicle stimulating hormone receptor 0.0261 0.2827 0.3988
Loa Loa (eye worm) hypothetical protein 0.0019 0.0088 0.0124
Brugia malayi Protein kinase domain containing protein 0.0018 0.0077 0.01
Echinococcus granulosus calcium activated potassium channel 0.0046 0.0398 0.044
Trichomonas vaginalis D-aminoacylase, putative 0.004 0.0325 0.1096
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0049 0.043 0.0475
Loa Loa (eye worm) hypothetical protein 0.0049 0.043 0.0607
Trichomonas vaginalis set domain proteins, putative 0.0263 0.2841 1
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.0104 0.1051 0.1051
Brugia malayi Sex muscle abnormal protein 5 0.0017 0.0068 0.0088
Echinococcus granulosus tyrosine protein kinase Fyn 0.0054 0.0487 0.0538
Echinococcus multilocularis Niemann Pick C1 protein 0.0156 0.1632 0.1632
Loa Loa (eye worm) hypothetical protein 0.0013 0.0023 0.0032
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0104 0.1051 0.1476
Echinococcus granulosus beta LACTamase domain containing family member 0.004 0.0325 0.0359
Trypanosoma brucei ATP-dependent DEAD/H DNA helicase recQ, putative 0.0013 0.0018 0.0047
Toxoplasma gondii cathepsin CPL 0.0019 0.0084 0.0633
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0019 0.0084 0.0245
Trichomonas vaginalis PIKK family atypical protein kinase 0.005 0.0436 0.1491
Trypanosoma cruzi mitogen activated protein kinase 4, putative 0.0056 0.0512 0.4857
Plasmodium falciparum ataxin-2 like protein, putative 0.0028 0.019 0.1567
Plasmodium falciparum ADP-dependent DNA helicase RecQ 0.0021 0.0109 0.0854
Trichomonas vaginalis ran, putative 0.0026 0.0165 0.0529
Leishmania major hypothetical protein, conserved 0.004 0.0325 0.3039
Entamoeba histolytica protein kinase, putative 0.0014 0.0028 0.0065
Schistosoma mansoni tar DNA-binding protein 0.007 0.0666 0.0778
Schistosoma mansoni niemann-pick C1 (NPC1) 0.0111 0.1124 0.1317
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.004 0.0325 0.1012
Echinococcus granulosus fibroblast growth factor receptor 4 0.0114 0.1161 0.1282
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0019 0.0084 0.0245
Giardia lamblia Pyruvate kinase 0.0074 0.0708 0.591
Schistosoma mansoni cpg binding protein 0.0032 0.0234 0.0269
Chlamydia trachomatis acylglycerophosphoethanolamine acyltransferase 0.0021 0.0117 0.0385
Toxoplasma gondii histone lysine methyltransferase SET1 0.0061 0.0568 0.4914
Schistosoma mansoni serine/threonine protein kinase 0.0042 0.0352 0.0408
Echinococcus multilocularis protein dispatched 1 0.0053 0.0477 0.0477
Trypanosoma brucei pyruvate kinase 1 0.0074 0.0708 0.6773
Schistosoma mansoni hypothetical protein 0.0045 0.0384 0.0445
Echinococcus granulosus expressed protein 0.0813 0.9054 1
Loa Loa (eye worm) hypothetical protein 0.0103 0.1035 0.1461
Brugia malayi RNA recognition motif domain containing protein 0.007 0.0666 0.0932
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0036 0.0287 0.0397
Brugia malayi steroid hormone receptor 0.0104 0.1051 0.1476
Schistosoma mansoni hypothetical protein 0.0036 0.0287 0.0331
Echinococcus granulosus aldehyde dehydrogenase mitochondrial 0.0067 0.0633 0.07
Leishmania major cathepsin L-like protease 0.0071 0.0672 0.6418
Onchocerca volvulus 0.0013 0.0023 0.0053
Echinococcus granulosus geminin 0.0205 0.2186 0.2414
Echinococcus multilocularis neuroglian 0.0016 0.0058 0.0058
Loa Loa (eye worm) hypothetical protein 0.0013 0.0021 0.0029
Echinococcus multilocularis expressed conserved protein 0.0102 0.103 0.103
Onchocerca volvulus 0.0012 0.0015 0.003
Echinococcus multilocularis phosphatidylinositol 3 and 4 kinase 0.0017 0.0064 0.0064
Echinococcus multilocularis regulator of G protein signaling 7 0.0042 0.0347 0.0347
Echinococcus multilocularis Ankyrin 0.0014 0.0034 0.0034
Onchocerca volvulus 0.0019 0.0084 0.0253
Echinococcus multilocularis Regulator of G protein signaling 20 0.0042 0.0347 0.0347
Loa Loa (eye worm) tyrosyl-DNA phosphodiesterase 0.0073 0.07 0.0987
Trypanosoma cruzi cysteine peptidase, putative 0.0019 0.0084 0.0697
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0071 0.0672 0.6418
Schistosoma mansoni NADP-specific isocitrate dehydrogenase 0.0017 0.0073 0.0078
Echinococcus multilocularis axis inhibition protein axin 0.0042 0.0347 0.0347
Trypanosoma brucei hypothetical protein, conserved 0.004 0.0325 0.3039
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0104 0.1051 0.1476
Loa Loa (eye worm) MH2 domain-containing protein 0.038 0.4168 0.5881
Brugia malayi Nuclear hormone receptor E75 0.0049 0.043 0.0599
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0018 0.008 0.0653
Brugia malayi Cathepsin L-like precursor 0.0012 0.0015 0.0013
Loa Loa (eye worm) hypothetical protein 0.0055 0.0497 0.0701
Brugia malayi orphan nuclear receptor NR2E1 0.0049 0.043 0.0599
Echinococcus multilocularis tyrosine protein kinase Btk29A 0.0022 0.0123 0.0123
Leishmania major acetoin dehydrogenase e3 component-like protein 0.0018 0.008 0.0653
Onchocerca volvulus 0.0018 0.0077 0.023
Loa Loa (eye worm) phosphatidylinositol 3 0.0017 0.0064 0.009
Trichomonas vaginalis glucosamine-6-phosphate isomerase, putative 0.0112 0.1143 0.3992
Trypanosoma brucei phosphatidylinositol 3-related kinase, putative 0.0017 0.0064 0.0493
Plasmodium falciparum cysteine proteinase falcipain 2b 0.0019 0.0084 0.0633
Toxoplasma gondii pyruvate kinase PyKII 0.0038 0.0303 0.2566
Plasmodium falciparum pyruvate kinase 2 0.0038 0.0303 0.2566
Brugia malayi MAP kinase sur-1 0.0056 0.0512 0.0714
Trichomonas vaginalis adenylate and guanylate cyclases, putative 0.0047 0.0404 0.1375
Echinococcus multilocularis tyrosine protein phosphatase non receptor type 0.0013 0.0023 0.0023
Echinococcus multilocularis calcium activated potassium channel 0.0046 0.0398 0.0398
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0104 0.1051 0.1051
Echinococcus granulosus melanoma receptor tyrosine protein kinase 0.0093 0.092 0.1016
Loa Loa (eye worm) hypothetical protein 0.0014 0.0037 0.0052
Echinococcus granulosus tyrosine protein kinase Fyn 0.0054 0.0487 0.0538
Entamoeba histolytica hypothetical protein 0.0042 0.0347 0.1659
Giardia lamblia Flap structure-specific endonuclease 0.0029 0.02 0.1134
Brugia malayi hypothetical protein 0.0042 0.0347 0.0481
Loa Loa (eye worm) hypothetical protein 0.0013 0.0021 0.0029
Echinococcus granulosus mothers against decapentaplegic 5 0.0026 0.0168 0.0185
Trichomonas vaginalis PIKK family atypical protein kinase 0.0027 0.0178 0.0575
Mycobacterium tuberculosis Probable lipase LipE 0.004 0.0325 0.1012
Echinococcus multilocularis regulator of G protein signaling 3 0.0042 0.0347 0.0347
Brugia malayi Pyruvate kinase, muscle isozyme 0.0074 0.0708 0.0992
Toxoplasma gondii glucose-6-phosphate 1-dehydrogenase 0.0067 0.0636 0.551
Mycobacterium tuberculosis Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras 0.0133 0.1372 0.4898
Trichomonas vaginalis PIKK family atypical protein kinase 0.003 0.0211 0.0691
Schistosoma mansoni tyrosine kinase 0.0088 0.0865 0.1013
Toxoplasma gondii thioredoxin reductase 0.0052 0.0466 0.4006
Brugia malayi AMP-binding enzyme family protein 0.0029 0.0199 0.0272
Brugia malayi Pre-SET motif family protein 0.0231 0.2482 0.3496
Schistosoma mansoni tyrosine kinase 0.0169 0.1781 0.2092
Echinococcus multilocularis SH2 motif 0.0013 0.0023 0.0023
Trypanosoma cruzi tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0073 0.07 0.6688
Loa Loa (eye worm) TK/FER protein kinase 0.0018 0.0077 0.0109
Brugia malayi Tyrosine-protein kinase abl-1 0.0022 0.0123 0.0165
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0028 0.0194 0.0633
Onchocerca volvulus Pyruvate kinase homolog 0.0074 0.0708 0.2269
Echinococcus granulosus single minded 2 0.0133 0.1381 0.1525
Echinococcus granulosus histone lysine methyltransferase setb 0.0034 0.0256 0.0283
Schistosoma mansoni regulator of G protein signaling 0.0042 0.0347 0.0401
Onchocerca volvulus Pyruvate kinase homolog 0.0074 0.0708 0.2269
Trypanosoma cruzi PAS-domain containing phosphoglycerate kinase, putative 0.0047 0.0404 0.3808
Brugia malayi Cathepsin L-like precursor 0.0019 0.0084 0.0111
Brugia malayi Cytochrome P450 family protein 0.0058 0.0529 0.0738
Loa Loa (eye worm) protein-tyrosine phosphatase 0.0013 0.0023 0.0032
Trypanosoma brucei isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0017 0.0073 0.0582
Echinococcus multilocularis tyrosine protein kinase ABL1 0.0018 0.0077 0.0077
Echinococcus multilocularis transcription factor Dp 1 0.0042 0.0352 0.0352
Echinococcus multilocularis Immunoglobulin 0.0013 0.0021 0.0021
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0055 0.0499 0.0581
Echinococcus granulosus insulin receptor 0.0057 0.0514 0.0568
Onchocerca volvulus 0.0019 0.0084 0.0253
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0049 0.043 0.043
Echinococcus multilocularis tyrosine protein phosphatase non receptor type 0.0013 0.0023 0.0023
Brugia malayi Protein kinase domain containing protein 0.0057 0.0514 0.0718
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0071 0.0672 0.6418
Trypanosoma brucei Lanosterol 14-alpha demethylase 0.0016 0.0052 0.0382
Loa Loa (eye worm) hypothetical protein 0.0135 0.1405 0.1982
Brugia malayi SRC-1 0.0054 0.0487 0.0679
Loa Loa (eye worm) hypothetical protein 0.004 0.0325 0.0458
Leishmania major cytochrome p450-like protein 0.0016 0.0052 0.0382
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0018 0.008 0.0653
Brugia malayi Cytochrome P450 family protein 0.0016 0.0052 0.0065
Schistosoma mansoni Tr4/Tr2 (homologue) 0.0104 0.1051 0.1232
Echinococcus granulosus smad 0.0026 0.0168 0.0185
Echinococcus multilocularis regulator of G protein signaling 7 0.0042 0.0347 0.0347
Mycobacterium tuberculosis Probable isocitrate dehydrogenase [NADP] Icd1 (oxalosuccinate decarboxylase) (IDH) (NADP+-specific ICDH) (IDP) 0.0017 0.0073 0.0076
Leishmania major cysteine peptidase A (CPA) 0.0019 0.0084 0.0697
Brugia malayi beta-lactamase family protein 0.004 0.0325 0.045
Loa Loa (eye worm) pyruvate kinase 0.0074 0.0708 0.0999
Schistosoma mansoni survival motor neuron protein 0.0053 0.0478 0.0556
Brugia malayi alpha keto acid dehydrogenase complex, E3 component, lipoamide dehydrogenase 0.0013 0.0026 0.0028
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0028 0.0194 0.0633
Mycobacterium tuberculosis Probable conserved lipoprotein 0.004 0.0325 0.1012
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0069 0.065 0.0758
Brugia malayi Pre-SET motif family protein 0.0034 0.0256 0.0353
Trichomonas vaginalis CMGC family protein kinase 0.0056 0.0512 0.1756
Loa Loa (eye worm) hypothetical protein 0.0029 0.0206 0.0291
Brugia malayi Pyruvate kinase, M2 isozyme 0.0074 0.0708 0.0992
Brugia malayi MH2 domain containing protein 0.0026 0.0168 0.0228
Mycobacterium ulcerans flavoprotein disulfide reductase 0.0018 0.008 0.021
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0018 0.008 0.0653
Trypanosoma cruzi tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0073 0.07 0.6688
Echinococcus granulosus calcium activated potassium channel variant 0.0043 0.0357 0.0394
Echinococcus granulosus tyrosine protein kinase HCK 0.0037 0.0294 0.0325
Schistosoma mansoni nuclear hormone receptor 0.0104 0.1051 0.1232
Schistosoma mansoni tensin 0.0013 0.0023 0.0019
Loa Loa (eye worm) phosphatidylinositol 3 0.005 0.0436 0.0616
Echinococcus granulosus tyrosine protein kinase Btk29A 0.0022 0.0123 0.0136
Echinococcus multilocularis GPCR, family 2 0.0036 0.0287 0.0287
Echinococcus granulosus cathepsin l cysteine peptidase 0.0019 0.0084 0.0093
Brugia malayi Smad1 0.0026 0.0168 0.0228
Loa Loa (eye worm) MH1 domain-containing protein 0.0012 0.0006 0.0009
Echinococcus granulosus tyrosine kinase 0.005 0.0441 0.0487
Loa Loa (eye worm) hypothetical protein 0.0014 0.0038 0.0053
Onchocerca volvulus 0.0103 0.1035 0.3325
Echinococcus granulosus snurportin 1 0.0372 0.4072 0.4498
Plasmodium falciparum dihydrolipoyl dehydrogenase, mitochondrial 0.0018 0.008 0.0593
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.0104 0.1051 0.1161
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0018 0.008 0.0653
Trypanosoma cruzi cytochrome P450, putative 0.0025 0.0161 0.1447
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0115 0.1177 0.1661
Entamoeba histolytica pyruvate kinase, putative 0.0051 0.0456 0.2208
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0049 0.043 0.137
Mycobacterium ulcerans long-chain-fatty-acid--CoA ligase 0.0029 0.0199 0.1103
Trichomonas vaginalis penicillin-binding protein, putative 0.004 0.0325 0.1096
Trypanosoma brucei importin beta-1 subunit, putative 0.0035 0.0268 0.2489
Loa Loa (eye worm) hypothetical protein 0.0104 0.1051 0.1483
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0019 0.0084 0.0245
Leishmania major target of rapamycin kinase (TOR) kinase 3 0.004 0.0322 0.3012
Schistosoma mansoni protein tyrosine phosphatase n11 (shp2) 0.0013 0.0023 0.0019
Echinococcus multilocularis Immunoglobulin 0.0013 0.0021 0.0021
Brugia malayi aryl hydrocarbon receptor AHR-1 0.0239 0.2573 0.3625
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.0053 0.0478 0.0666
Mycobacterium ulcerans sugar phosphate isomerases/epimerases 0.0022 0.0127 0.0564
Schistosoma mansoni tar DNA-binding protein 0.007 0.0666 0.0778
Trypanosoma cruzi STE/STE11 serine/threonine-protein kinase, putative 0.0047 0.041 0.3864
Echinococcus granulosus Niemann Pick C1 protein 0.0156 0.1632 0.1803
Leishmania major 2-oxoglutarate dehydrogenase, e3 component, lipoamidedehydrogenase-like protein 0.0018 0.008 0.0653
Trypanosoma cruzi mitogen activated protein kinase 2, putative 0.0056 0.0512 0.4857
Schistosoma mansoni calcium-activated potassium channel 0.0046 0.0393 0.0456
Echinococcus multilocularis RUN 0.0022 0.0122 0.0122
Schistosoma mansoni tyrosine kinase 0.0093 0.092 0.1077
Schistosoma mansoni serine/threonine protein kinase 0.0042 0.0352 0.0408
Trichomonas vaginalis PIKK family atypical protein kinase 0.004 0.0322 0.1084
Trypanosoma cruzi PAB1-binding protein , putative 0.0028 0.019 0.1726
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0034 0.0256 0.0294
Echinococcus granulosus Nuclear hormone receptor HR96 0.0049 0.043 0.0475
Brugia malayi dihydrolipoyl dehydrogenase, mitochondrial precursor, putative 0.0018 0.008 0.0104
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.003 0.0212 0.0299
Brugia malayi pyruvate kinase 0.0016 0.0051 0.0063
Wolbachia endosymbiont of Brugia malayi dihydrolipoamide dehydrogenase E3 component 0.0018 0.008 0.5
Echinococcus multilocularis thyroid hormone receptor alpha 0.0243 0.2623 0.2623
Brugia malayi latrophilin 2 splice variant baaae 0.0079 0.0765 0.1072
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0018 0.008 0.0653
Loa Loa (eye worm) DR-78 0.0049 0.043 0.0607
Schistosoma mansoni adapter molecule crk 0.0017 0.0068 0.0073
Schistosoma mansoni lamin 0.003 0.0212 0.0243
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD7 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.002 0.0104 0.0191
Trypanosoma brucei mitogen activated protein kinase 4, putative 0.0056 0.0512 0.4857
Trichomonas vaginalis glucosamine-6-phosphate isomerase, putative 0.0112 0.1143 0.3992
Schistosoma mansoni smad1 5 8 and 0.0026 0.0168 0.0191
Loa Loa (eye worm) large conductance calcium-activated potassium channel alpha subunit ai 0.0043 0.0357 0.0503
Brugia malayi cytokine inducible SH2-containing protein 5 0.0013 0.0023 0.0023
Echinococcus multilocularis expressed protein 0.0813 0.9054 0.9054
Echinococcus multilocularis 0.0051 0.0452 0.0452
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0036 0.0287 0.0317
Trichomonas vaginalis conserved hypothetical protein 0.0042 0.0347 0.1173
Brugia malayi Variant SH3 domain containing protein 0.0017 0.0068 0.0088
Trichomonas vaginalis conserved hypothetical protein 0.0047 0.0403 0.1372
Schistosoma mansoni chimerin-related rho-gtpase-activating protein 0.0013 0.0023 0.0019
Onchocerca volvulus Huntingtin homolog 0.0135 0.1405 0.4519
Toxoplasma gondii NADPH-glutathione reductase 0.0018 0.008 0.0593
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0055 0.0499 0.0551
Echinococcus multilocularis Polycystic kidney disease protein 0.0022 0.0122 0.0122
Schistosoma mansoni cathepsin F (C01 family) 0.0012 0.0015 0.0011
Schistosoma mansoni regulator of G protein signaling 17 19 20 (rgs17 19 20) 0.0042 0.0347 0.0401
Onchocerca volvulus Netrin receptor homolog 0.0017 0.007 0.0207
Onchocerca volvulus 0.0029 0.0199 0.0622
Mycobacterium tuberculosis Probable aldehyde dehydrogenase 0.0067 0.0633 0.2157
Echinococcus granulosus N chimaerin 0.0013 0.0023 0.0025
Schistosoma mansoni hypothetical protein 0.0053 0.0478 0.0556
Trichomonas vaginalis glutathione reductase, putative 0.0018 0.008 0.0229
Schistosoma mansoni hypothetical protein 0.0079 0.0765 0.0895
Echinococcus granulosus cathepsin l1 0.0019 0.0084 0.0093
Brugia malayi CHE-14 protein 0.0047 0.0403 0.056
Loa Loa (eye worm) latrophilin receptor protein 2 0.0036 0.0287 0.0405
Loa Loa (eye worm) CMGC/MAPK/ERK1 protein kinase 0.0056 0.0512 0.0722
Entamoeba histolytica recQ family helicase, putative 0.0013 0.0018 0.0012
Loa Loa (eye worm) hypothetical protein 0.0013 0.0023 0.0032
Trichomonas vaginalis PIKK family atypical protein kinase 0.0033 0.0252 0.0837
Schistosoma mansoni hypothetical protein 0.0045 0.0384 0.0445
Schistosoma mansoni hypothetical protein 0.0013 0.0017 0.0012
Brugia malayi glutathione reductase 0.0052 0.0466 0.0649
Schistosoma mansoni tar DNA-binding protein 0.007 0.0666 0.0778
Loa Loa (eye worm) hypoxia-induced factor 1 0.0167 0.1755 0.2477
Leishmania major cathepsin L-like protease 0.0019 0.0084 0.0697
Loa Loa (eye worm) sex muscle abnormal protein 5 0.0017 0.0068 0.0097
Chlamydia trachomatis glucose-6-phosphate 1-dehydrogenase 0.0103 0.104 1
Plasmodium vivax flap endonuclease 1, putative 0.0029 0.02 0.166
Leishmania major cathepsin L-like protease 0.0019 0.0084 0.0697
Echinococcus granulosus Protein patched homolog 1 0.0047 0.0403 0.0445
Onchocerca volvulus 0.004 0.0325 0.103
Brugia malayi Niemann-Pick C1 protein precursor 0.0109 0.1105 0.1551
Schistosoma mansoni hypothetical protein 0.0452 0.4982 0.5864
Echinococcus multilocularis potassium large conductance calcium activated 0.0046 0.0393 0.0393
Echinococcus granulosus lamin 0.003 0.0212 0.0234
Mycobacterium tuberculosis NADPH-dependent mycothiol reductase Mtr 0.0052 0.0466 0.1535
Echinococcus granulosus bloom syndrome protein 0.0024 0.0142 0.0157
Trypanosoma brucei flap endonuclease-1 (FEN-1), putative 0.0029 0.02 0.1827
Onchocerca volvulus 0.0032 0.0234 0.0736
Brugia malayi PXA domain containing protein 0.0042 0.0347 0.0481
Mycobacterium ulcerans long-chain-fatty-acid-CoA ligase 0.0029 0.0199 0.1103
Onchocerca volvulus Protein ultraspiracle homolog 0.0104 0.1051 0.3376
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0071 0.0672 0.6418
Plasmodium vivax dihydrolipoyl dehydrogenase, mitochondrial, putative 0.0018 0.008 0.0593
Trypanosoma cruzi cysteine peptidase, putative 0.0071 0.0672 0.6418
Trichomonas vaginalis esterase, putative 0.004 0.0325 0.1096
Mycobacterium ulcerans glucose-6-phosphate 1-dehydrogenase 0.0103 0.104 0.7434
Loa Loa (eye worm) SH2 domain-containing protein 0.0013 0.0023 0.0032
Schistosoma mansoni tensin-related 0.0013 0.0023 0.0019
Brugia malayi beta-lactamase family protein 0.004 0.0325 0.045
Mycobacterium leprae DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE 0.0133 0.1372 1
Echinococcus multilocularis importin subunit beta 1 0.0035 0.0268 0.0268
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0071 0.0672 0.6418
Leishmania major target of rapamycin (TOR) kinase 1, putative 0.005 0.0436 0.4125
Brugia malayi Cytochrome P450 family protein 0.0025 0.0161 0.0219
Schistosoma mansoni tyrosine kinase 0.0022 0.0123 0.0138
Brugia malayi DNA-(Apurinic or apyrimidinic site) lyase 0.0085 0.0832 0.1167
Echinococcus multilocularis smad 0.0026 0.0168 0.0168
Echinococcus granulosus Regulator of G protein signaling 20 0.0042 0.0347 0.0383
Echinococcus multilocularis epidermal growth factor receptor 0.0093 0.092 0.092
Brugia malayi Regulator of G protein signaling domain containing protein 0.0042 0.0347 0.0481
Brugia malayi Calcitonin receptor-like protein seb-1 0.0115 0.1177 0.1654
Loa Loa (eye worm) PXA domain-containing protein 0.0042 0.0347 0.0489
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.0104 0.1051 0.1483
Echinococcus granulosus SHC transforming protein 3 0.0013 0.0023 0.0025
Echinococcus granulosus phosphatidylinositol 3 kinase regulatory subunit 0.0013 0.0023 0.0025
Loa Loa (eye worm) RhoGAP domain-containing protein 0.0013 0.0023 0.0032
Loa Loa (eye worm) hypothetical protein 0.0135 0.1405 0.1982
Leishmania major protein kinase, putative 0.0047 0.041 0.3864
Leishmania major cathepsin L-like protease 0.0071 0.0672 0.6418
Echinococcus multilocularis SH2 domain containing protein 7 0.0013 0.0023 0.0023
Entamoeba histolytica FKBP-rapamycin associated protein (FRAP), putative 0.005 0.0436 0.2108
Brugia malayi Nuclear hormone receptor family member nhr-41 0.0104 0.1051 0.1476
Echinococcus multilocularis tyrosine protein kinase Fps85D 0.0018 0.0077 0.0077
Echinococcus granulosus cpg binding protein 0.0034 0.0254 0.0281
Loa Loa (eye worm) hypothetical protein 0.0021 0.0117 0.0165
Brugia malayi Protein kinase domain containing protein 0.0018 0.0077 0.01
Loa Loa (eye worm) hypothetical protein 0.0085 0.0832 0.1174
Echinococcus multilocularis cathepsin L cysteine protease 0.0019 0.0084 0.0084
Echinococcus multilocularis tyrosine protein kinase Fgr 0.0054 0.0487 0.0487
Mycobacterium ulcerans aldehyde dehydrogenase 0.0067 0.0633 0.4377
Echinococcus granulosus Immunoglobulin 0.0013 0.0021 0.0023
Echinococcus granulosus regulator of G protein signaling 7 0.0042 0.0347 0.0383
Echinococcus granulosus axis inhibition protein axin 0.0042 0.0347 0.0383
Brugia malayi glucose-6-phosphate dehydrogenase 0.0103 0.104 0.146
Loa Loa (eye worm) TK/FER protein kinase 0.0018 0.0077 0.0109
Loa Loa (eye worm) hypothetical protein 0.0036 0.0287 0.0405
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0054 0.0487 0.0487
Echinococcus granulosus growth factor receptor bound protein 2 0.0017 0.0068 0.0076
Mycobacterium tuberculosis Probable endonuclease IV End (endodeoxyribonuclease IV) (apurinase) 0.0085 0.0832 0.2895
Brugia malayi hypothetical protein 0.0022 0.0122 0.0163
Schistosoma mansoni intermediate filament proteins 0.003 0.0212 0.0243
Loa Loa (eye worm) hypothetical protein 0.0051 0.0456 0.0644
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0034 0.0256 0.0294
Echinococcus multilocularis cathepsin L cysteine protease 0.0019 0.0084 0.0084
Leishmania major tyrosyl-DNA phosphodiesterase 1 0.0073 0.07 0.6688
Brugia malayi SH2 domain containing protein 0.0013 0.0023 0.0023
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0018 0.008 0.0653
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.005 0.0436 0.0608
Brugia malayi ecdysone receptor 0.0049 0.043 0.0599
Loa Loa (eye worm) hypothetical protein 0.0042 0.0347 0.0489
Loa Loa (eye worm) doublecortin family protein 0.0022 0.0122 0.0171
Loa Loa (eye worm) hypothetical protein 0.0013 0.0021 0.0029
Brugia malayi Nuclear hormone receptor family member nhr-3 0.0104 0.1051 0.1476
Entamoeba histolytica SH2-protein kinase domain containing protein 0.0014 0.0028 0.0065
Schistosoma mansoni regulator of G protein signaling 0.0042 0.0347 0.0401
Trichomonas vaginalis D-aminoacylase, putative 0.004 0.0325 0.1096
Schistosoma mansoni serine/threonine protein kinase 0.0056 0.0512 0.0596
Entamoeba histolytica cysteine proteinase, putative 0.0019 0.0084 0.0346
Schistosoma mansoni tyrosine kinase 0.0022 0.0123 0.0138
Brugia malayi hypothetical protein 0.0262 0.2828 0.3985
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0034 0.0256 0.0256
Brugia malayi Immunoglobulin I-set domain containing protein 0.0014 0.0033 0.0038
Schistosoma mansoni ankyrin 23/unc44 0.0014 0.0033 0.0032
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0071 0.0672 0.6418
Loa Loa (eye worm) hypothetical protein 0.0012 0.0015 0.0022
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0071 0.0672 0.6418
Echinococcus granulosus basic fibroblast growth factor receptor 1 A 0.0114 0.1161 0.1282
Loa Loa (eye worm) pyruvate kinase 0.0016 0.0051 0.0072
Toxoplasma gondii pyruvate kinase PyK1 0.0074 0.0708 0.6152
Brugia malayi ecdysteroid receptor 0.0104 0.1051 0.1476
Brugia malayi follicle stimulating hormone receptor 0.0261 0.2827 0.3983
Brugia malayi photoreceptor-specific nuclear receptor 0.0104 0.1051 0.1476
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.0104 0.1051 0.1483
Brugia malayi Immunoglobulin I-set domain containing protein 0.0013 0.0021 0.002
Echinococcus multilocularis epidermal growth factor receptor 0.0169 0.1781 0.1781
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0055 0.0499 0.0551
Trichomonas vaginalis PIKK family atypical protein kinase 0.005 0.0436 0.1491
Brugia malayi conserved hypotetical protein 0.0049 0.043 0.0599
Onchocerca volvulus 0.0018 0.0077 0.023
Brugia malayi hypothetical protein 0.0022 0.0122 0.0163
Trypanosoma cruzi isocitrate dehydrogenase, putative 0.0017 0.0073 0.0582
Brugia malayi nuclear receptor NHR-67 0.0049 0.043 0.0599
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0049 0.043 0.043
Schistosoma mansoni aldehyde dehydrogenase 0.0067 0.0633 0.0739
Echinococcus multilocularis tyrosine protein kinase Abl 0.0022 0.0123 0.0123
Brugia malayi Furin-like cysteine rich region family protein 0.0169 0.1781 0.2507
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.0026 0.0165 0.1478
Echinococcus multilocularis pyruvate kinase 0.0038 0.0303 0.0303
Trypanosoma cruzi PAS-domain containing phosphoglycerate kinase, putative 0.0047 0.0404 0.3808
Loa Loa (eye worm) RNA recognition domain-containing protein domain-containing protein 0.007 0.0666 0.094
Trichomonas vaginalis PIKK family atypical protein kinase 0.005 0.0436 0.1491
Echinococcus multilocularis flap endonuclease 1 0.0029 0.02 0.02
Trypanosoma brucei importin beta-1 subunit, putative 0.0035 0.0268 0.2489
Echinococcus multilocularis N chimaerin 0.0013 0.0023 0.0023
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0071 0.0672 0.6418
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD2 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0029 0.0199 0.0544
Schistosoma mansoni SH2A 0.0013 0.0023 0.0019
Loa Loa (eye worm) hypothetical protein 0.004 0.0325 0.0458
Echinococcus multilocularis regulator of G protein signaling 3 0.0042 0.0347 0.0347
Leishmania major cathepsin L-like protease 0.0019 0.0084 0.0697
Echinococcus multilocularis snurportin 1 0.0372 0.4072 0.4072
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0054 0.0487 0.0487
Brugia malayi PXA domain containing protein 0.0042 0.0347 0.0481
Brugia malayi nuclear hormone receptor 0.0104 0.1051 0.1476
Plasmodium vivax importin-beta 2, putative 0.0035 0.0268 0.2261
Echinococcus granulosus dihydrolipoamide dehydrogenase 0.0018 0.008 0.0088
Trichomonas vaginalis PIKK family atypical protein kinase 0.0037 0.0293 0.0982
Brugia malayi hypothetical protein 0.0018 0.0077 0.01
Loa Loa (eye worm) nucleolar RNA-associated protein alpha 0.0372 0.4072 0.5746
Echinococcus multilocularis lamin 0.003 0.0212 0.0212
Brugia malayi nuclear hormone receptor family member odr-7 0.0049 0.043 0.0599
Loa Loa (eye worm) hypothetical protein 0.0049 0.043 0.0607
Loa Loa (eye worm) hypothetical protein 0.0028 0.019 0.0268
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0019 0.0084 0.0245
Trypanosoma brucei protein kinase, putative 0.0056 0.0512 0.4857
Trichomonas vaginalis adenylate and guanylate cyclases, putative 0.0047 0.0404 0.1375
Echinococcus granulosus proto oncogene tyrosine protein kinase LCK 0.0054 0.0487 0.0538
Schistosoma mansoni retinoic acid receptor RXR 0.0309 0.3364 0.3957
Loa Loa (eye worm) hypothetical protein 0.0049 0.043 0.0607
Loa Loa (eye worm) hypothetical protein 0.0049 0.043 0.0607
Schistosoma mansoni hepatocyte nuclear factor 4-alpha (hnf-4-alpha) 0.0049 0.043 0.05
Trypanosoma cruzi STE group serine/threonine-protein kinase, putative 0.0047 0.041 0.3864
Loa Loa (eye worm) hypothetical protein 0.0104 0.1051 0.1483
Schistosoma mansoni regulator of G protein signaling 0.0042 0.0347 0.0401
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD7 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0029 0.0199 0.111
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.004 0.0325 0.2054
Trichomonas vaginalis PIKK family atypical protein kinase 0.004 0.0322 0.1084
Loa Loa (eye worm) RGS-3 protein 0.0042 0.0347 0.0489
Onchocerca volvulus 0.0013 0.0023 0.0053
Echinococcus granulosus SH2 motif 0.0013 0.0023 0.0025
Schistosoma mansoni smad 0.0026 0.0168 0.0191
Schistosoma mansoni steroid hormone receptor ad4bp 0.0104 0.1051 0.1232
Trichomonas vaginalis PIKK family atypical protein kinase 0.0037 0.0293 0.0982
Schistosoma mansoni serine/threonine protein kinase 0.0042 0.0352 0.0408
Schistosoma mansoni Smad4 0.0026 0.0168 0.0191
Loa Loa (eye worm) MH1 domain-containing protein 0.0026 0.0168 0.0237
Brugia malayi nuclear receptor RXR 0.0055 0.0497 0.0693
Brugia malayi Importin beta-1 subunit 0.0035 0.0268 0.0371
Schistosoma mansoni transcription factor LCR-F1 0.0189 0.2013 0.2365
Mycobacterium ulcerans beta-lactamase 0.004 0.0325 0.2054
Schistosoma mansoni calcium-activated potassium channel 0.0012 0.0013 0.0008
Echinococcus multilocularis suppressor of cytokine signaling 7 0.0013 0.0023 0.0023
Echinococcus multilocularis mitogen activated protein kinase 3 0.0056 0.0512 0.0512
Echinococcus granulosus sterol regulatory element binding protein 0.0047 0.0403 0.0445
Loa Loa (eye worm) hypothetical protein 0.0639 0.7087 1
Schistosoma mansoni tyrosine kinase 0.0018 0.0078 0.0085
Echinococcus granulosus pyruvate kinase 0.0038 0.0303 0.0335
Loa Loa (eye worm) TK/FER protein kinase 0.0018 0.0077 0.0109
Echinococcus granulosus thioredoxin glutathione reductase 0.0052 0.0466 0.0514
Brugia malayi STAT protein, DNA binding domain containing protein 0.0184 0.1956 0.2753
Loa Loa (eye worm) TK/FER protein kinase 0.0018 0.0077 0.0109
Trypanosoma cruzi glucose-6-phosphate 1-dehydrogenase, putative 0.0034 0.0261 0.2418
Trypanosoma brucei pyruvate kinase 1, putative 0.0074 0.0708 0.6773
Loa Loa (eye worm) hypothetical protein 0.0042 0.0347 0.0489
Entamoeba histolytica hypothetical protein 0.0042 0.0347 0.1659
Echinococcus multilocularis Aryl hydrocarbon receptor nuclear 0.0048 0.0416 0.0416
Loa Loa (eye worm) hypothetical protein 0.0013 0.0023 0.0032
Echinococcus multilocularis beta adrenergic receptor kinase 0.0042 0.0352 0.0352
Trypanosoma cruzi isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0017 0.0073 0.0582
Loa Loa (eye worm) Papain cysteine protease/cathepsin propeptide inhibitor-containing protein 0.0019 0.0084 0.0119
Schistosoma mansoni vav2 0.0013 0.0023 0.0019
Brugia malayi nuclear receptor subfamily 1, group D, member 1, putative 0.0049 0.043 0.0599
Schistosoma mansoni pyruvate kinase 0.0038 0.0303 0.035
Mycobacterium ulcerans hypothetical protein 0.0022 0.0127 0.0564
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0071 0.0672 0.6418
Schistosoma mansoni hypothetical protein 0.0036 0.0287 0.0331
Loa Loa (eye worm) SRC-1 0.0054 0.0487 0.0687
Echinococcus granulosus survival motor neuron protein 1 0.0262 0.2828 0.3123
Echinococcus granulosus NADP dependent isocitrate dehydrogenase 0.0017 0.0073 0.008
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0036 0.0287 0.0317
Schistosoma mansoni nuclear receptor 0.0049 0.043 0.05
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.0104 0.1051 0.1483
Schistosoma mansoni hypothetical protein 0.0014 0.0033 0.0032
Echinococcus multilocularis pyruvate kinase 0.0074 0.0708 0.0708
Plasmodium falciparum ataxin-2 like protein, putative 0.0028 0.019 0.1567
Schistosoma mansoni zinc finger protein 0.0049 0.043 0.05
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.0104 0.1051 0.1483
Loa Loa (eye worm) cytokine inducible SH2-containing protein 5 0.0013 0.0023 0.0032
Mycobacterium leprae conserved hypothetical protein 0.004 0.0325 0.2066
Plasmodium falciparum importin beta, putative 0.0035 0.0268 0.2261
Trypanosoma cruzi cytochrome P450, putative 0.0025 0.0161 0.1447
Echinococcus granulosus tensin C1 domain containing phosphatase 0.0013 0.0023 0.0025
Loa Loa (eye worm) hypothetical protein 0.0049 0.043 0.0607
Brugia malayi CXXC zinc finger family protein 0.0032 0.0234 0.0322
Loa Loa (eye worm) pyruvate kinase 0.0074 0.0708 0.0999
Echinococcus multilocularis insulin growth factor 1 receptor beta 0.0057 0.0514 0.0514
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0115 0.1177 0.1654
Echinococcus multilocularis retinoic acid receptor rxr beta a retinoic acid receptor rxr alpha a retinoic acid receptor rxr alpha 0.0254 0.2742 0.2742
Loa Loa (eye worm) cytoplasmic intermediate filament protein 0.0016 0.0056 0.0079
Loa Loa (eye worm) hypothetical protein 0.0055 0.0497 0.0701
Onchocerca volvulus 0.0013 0.0023 0.0053
Echinococcus multilocularis NCK adaptor protein 0.0017 0.0068 0.0068
Echinococcus multilocularis calcium activated potassium channel variant 0.0043 0.0357 0.0357
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0189 0.2013 0.2223
Brugia malayi hypothetical protein 0.0055 0.0497 0.0693
Echinococcus multilocularis mothers against decapentaplegic 2 0.0012 0.0006 0.0006
Plasmodium falciparum thioredoxin reductase 0.0018 0.008 0.0593
Loa Loa (eye worm) hypothetical protein 0.0115 0.1177 0.1661
Brugia malayi hypothetical protein 0.0018 0.0079 0.0102
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0019 0.0084 0.0245
Echinococcus multilocularis survival motor neuron protein 1 0.0262 0.2828 0.2828
Loa Loa (eye worm) TK/FER protein kinase 0.0018 0.0077 0.0109
Trichomonas vaginalis conserved hypothetical protein 0.0042 0.0347 0.1173
Leishmania major hypothetical protein, conserved 0.0028 0.019 0.1726
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0014 0.0033 0.0047
Onchocerca volvulus Bile acid receptor homolog 0.0104 0.1051 0.3376
Schistosoma mansoni rab6-interacting 0.0022 0.0122 0.0136
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.004 0.0325 0.1012
Trypanosoma brucei glucose-6-phosphate 1-dehydrogenase 0.0103 0.104 1
Schistosoma mansoni tyrosyl-DNA phosphodiesterase 0.0073 0.07 0.0817
Loa Loa (eye worm) hypothetical protein 0.0104 0.1051 0.1483
Brugia malayi hypothetical protein 0.0049 0.043 0.0599
Echinococcus multilocularis suppressor of cytokine signaling 7 0.0013 0.0023 0.0023
Loa Loa (eye worm) MH2 domain-containing protein 0.0026 0.0168 0.0237
Plasmodium vivax ADP-dependent DNA helicase RecQ, putative 0.0016 0.0055 0.0377
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0104 0.1051 0.1476
Echinococcus granulosus tyrosine protein kinase ABL1 0.0018 0.0077 0.0085
Loa Loa (eye worm) hypothetical protein 0.0013 0.0021 0.0029
Onchocerca volvulus 0.0018 0.0077 0.023
Toxoplasma gondii isocitrate dehydrogenase 0.0017 0.0073 0.0528
Giardia lamblia GTP-binding nuclear protein RAN/TC4 0.0026 0.0165 0.0797
Plasmodium falciparum cysteine proteinase falcipain 3 0.0019 0.0084 0.0633
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0189 0.2013 0.2013
Echinococcus granulosus suppressor of cytokine signaling 7 0.0013 0.0023 0.0025
Echinococcus granulosus Aryl hydrocarbon receptor nuclear 0.0048 0.0416 0.046
Echinococcus granulosus glucose 6 phosphate 1 dehydrogenase 0.0103 0.104 0.1148
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.0104 0.1051 0.1161
Brugia malayi Fibronectin type III domain containing protein 0.0013 0.0021 0.002
Echinococcus multilocularis guanine nucleotide exchange factor VAV2 0.0013 0.0023 0.0023
Schistosoma mansoni cpg binding protein 0.0034 0.0254 0.0293
Schistosoma mansoni tar DNA-binding protein 0.007 0.0666 0.0778
Toxoplasma gondii target of rapamycin (TOR), putative 0.0037 0.0293 0.2475
Echinococcus granulosus roundabout 2 0.0016 0.0058 0.0064
Schistosoma mansoni hypothetical protein 0.0036 0.0287 0.0331
Echinococcus granulosus tyrosine protein kinase Src42A 0.0045 0.0387 0.0427
Toxoplasma gondii cytochrome p450 superfamily protein 0.0016 0.0052 0.0347
Schistosoma mansoni regulator of G protein signaling 3 rgs3 0.0042 0.0347 0.0401
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0071 0.0672 0.6418
Brugia malayi Cathepsin L-like precursor 0.0019 0.0084 0.0111
Leishmania major GTP-binding protein, putative 0.0026 0.0165 0.1478
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0056 0.0512 0.4857
Loa Loa (eye worm) TK protein kinase 0.0037 0.0294 0.0415
Onchocerca volvulus 0.0019 0.0084 0.0253
Brugia malayi Immunoglobulin I-set domain containing protein 0.0117 0.1198 0.1683
Schistosoma mansoni aldehyde dehydrogenase 0.0067 0.0633 0.0739
Echinococcus granulosus cathepsin l1 0.0012 0.0015 0.0017
Loa Loa (eye worm) AGC/GRK/BARK protein kinase 0.0042 0.0352 0.0497
Loa Loa (eye worm) hypothetical protein 0.0013 0.0023 0.0032
Brugia malayi Nuclear hormone receptor family member nhr-14 0.0104 0.1051 0.1476
Brugia malayi pyruvate kinase, muscle isozyme 0.0016 0.0051 0.0063
Trichomonas vaginalis PIKK family atypical protein kinase 0.004 0.0322 0.1084
Schistosoma mansoni flap endonuclease-1 0.0026 0.0169 0.0192
Brugia malayi hypothetical protein 0.0055 0.0497 0.0693
Echinococcus multilocularis nuclear receptor subfamily 1 group D 0.0055 0.0497 0.0497
Trypanosoma cruzi pyruvate kinase 2, putative 0.0074 0.0708 0.6773
Echinococcus multilocularis aldehyde dehydrogenase, mitochondrial 0.0067 0.0633 0.0633
Loa Loa (eye worm) hypothetical protein 0.0047 0.0403 0.0568
Trypanosoma cruzi PAB1-binding protein , putative 0.0028 0.019 0.1726
Schistosoma mansoni regulator of G protein signaling 0.0042 0.0347 0.0401
Echinococcus granulosus axis inhibition protein axin 0.0042 0.0347 0.0383
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0104 0.1051 0.1161
Loa Loa (eye worm) ctsf protein 0.0019 0.0084 0.0119
Trichomonas vaginalis conserved hypothetical protein 0.0042 0.0347 0.1173
Onchocerca volvulus Suppressor of cytokine signaling at 36E homolog 0.0013 0.0023 0.0053
Brugia malayi Latrophilin receptor protein 2 0.0036 0.0287 0.0397
Trichomonas vaginalis PIKK family atypical protein kinase 0.0037 0.0293 0.0982
Trypanosoma cruzi cysteine peptidase, clan CA, family C1, cathepsin L-like, putative 0.0064 0.0603 0.5745
Loa Loa (eye worm) TK/FER protein kinase 0.0018 0.0077 0.0109
Trypanosoma cruzi importin beta-1 subunit, putative 0.0028 0.0194 0.1765
Trichomonas vaginalis flap endonuclease-1, putative 0.0029 0.02 0.0655
Loa Loa (eye worm) hypothetical protein 0.0109 0.1105 0.1559
Plasmodium falciparum glucose-6-phosphate dehydrogenase-6-phosphogluconolactonase 0.0112 0.1143 1
Echinococcus multilocularis bloom syndrome protein 0.0024 0.0142 0.0142
Schistosoma mansoni hypothetical protein 0.0205 0.2186 0.2569
Brugia malayi SH2 domain containing protein 0.0013 0.0023 0.0023
Leishmania major cytochrome p450-like protein 0.0016 0.0052 0.0382
Trypanosoma brucei dihydrolipoyl dehydrogenase 0.0018 0.008 0.0653
Echinococcus granulosus cathepsin L cysteine proteinase 0.0019 0.0084 0.0093
Mycobacterium ulcerans dihydrolipoamide dehydrogenase 0.0018 0.008 0.021
Schistosoma mansoni chimerin-related rho-gtpase-activating protein 0.0013 0.0023 0.0019
Loa Loa (eye worm) nuclear factor I 0.0014 0.0037 0.0052
Onchocerca volvulus 0.0013 0.0023 0.0053
Loa Loa (eye worm) cysteine protease 0.0019 0.0084 0.0119
Trypanosoma cruzi Glucose-6-phosphate dehydrogenase, putative 0.0033 0.025 0.2309
Echinococcus multilocularis dihydrolipoamide dehydrogenase 0.0018 0.008 0.008
Echinococcus multilocularis isocitrate dehydrogenase 0.0017 0.0073 0.0073
Brugia malayi MH1 domain containing protein 0.0026 0.0168 0.0228
Schistosoma mansoni calcium-activated potassium channel 0.0043 0.0357 0.0413
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0017 0.0073 0.0073
Mycobacterium tuberculosis Probable esterase LipL 0.004 0.0325 0.1012
Brugia malayi Nuclear hormone receptor family member nhr-40 0.0104 0.1051 0.1476
Echinococcus granulosus cytoplasmic intermediate filament protein 0.0014 0.0038 0.0042
Echinococcus granulosus epidermal growth factor receptor 0.0093 0.092 0.1016
Mycobacterium leprae Probable pyruvate kinase PykA 0.0074 0.0708 0.4971
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.0104 0.1051 0.1232
Echinococcus granulosus nuclear factor of activated T cells 5 0.0072 0.0683 0.0755
Echinococcus multilocularis aryl hydrocarbon receptor 0.0287 0.3114 0.3114
Echinococcus multilocularis nuclear receptor subfamily 4 group A 0.0049 0.043 0.043
Schistosoma mansoni tyrosine kinase 0.0054 0.0487 0.0567
Schistosoma mansoni hypothetical protein 0.0013 0.0023 0.0019
Plasmodium vivax GTP-binding nuclear protein RAN/TC4, putative 0.0026 0.0165 0.1343
Trichomonas vaginalis D-aminoacylase, putative 0.004 0.0325 0.1096
Schistosoma mansoni tyrosine kinase 0.0057 0.0514 0.0599
Schistosoma mansoni thyroid hormone receptor 0.0243 0.2623 0.3084
Loa Loa (eye worm) TK/FER protein kinase 0.0018 0.0077 0.0109
Toxoplasma gondii pyruvate dehydrogenase complex subunit PDH-E3II 0.0018 0.008 0.0593
Trichomonas vaginalis PIKK family atypical protein kinase 0.004 0.0322 0.1084
Schistosoma mansoni aryl hydrocarbon receptor 0.042 0.4619 0.5436
Schistosoma mansoni vesicular amine transporter 0.0016 0.0057 0.006
Echinococcus multilocularis tyrosine protein kinase Fyn 0.005 0.0441 0.0441
Brugia malayi RNA binding protein 0.007 0.0666 0.0932
Mycobacterium tuberculosis Conserved hypothetical protein 0.0022 0.0127 0.0278
Trichomonas vaginalis penicillin-binding protein, putative 0.004 0.0325 0.1096
Brugia malayi Immunoglobulin I-set domain containing protein 0.0018 0.0075 0.0097
Echinococcus granulosus tyrosyl DNA phosphodiesterase 1 0.0073 0.07 0.0773
Loa Loa (eye worm) hypothetical protein 0.0079 0.0765 0.108
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0018 0.008 0.0653
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0017 0.0064 0.0081
Trichomonas vaginalis pyruvate kinase, putative 0.0074 0.0708 0.2453
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0055 0.0499 0.0581
Mycobacterium leprae PROBABLE NADH DEHYDROGENASE NDH 0.0119 0.1222 0.8862
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0019 0.0084 0.0245
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0019 0.0084 0.0245
Brugia malayi Nuclear hormone receptor family member nhr-49 0.0104 0.1051 0.1476
Leishmania major 4-coumarate:coa ligase-like protein 0.0029 0.0199 0.1809
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0032 0.0234 0.0259
Echinococcus multilocularis suppressor of cytokine signaling 6 0.0013 0.0023 0.0023
Loa Loa (eye worm) hypothetical protein 0.003 0.0219 0.0309
Echinococcus granulosus suppressor of cytokine signaling 6 0.0013 0.0023 0.0025
Leishmania major PAS-domain containing phosphoglycerate kinase, putative 0.0047 0.0404 0.3808
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.0104 0.1051 0.1232
Loa Loa (eye worm) TK/INSR protein kinase 0.0057 0.0514 0.0726
Mycobacterium tuberculosis Probable NADH dehydrogenase Ndh 0.0119 0.1222 0.4341
Echinococcus granulosus mitogen activated protein kinase 3 0.0056 0.0512 0.0565
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0055 0.0499 0.0696
Trichomonas vaginalis PIKK family atypical protein kinase 0.0042 0.0354 0.12
Loa Loa (eye worm) hypothetical protein 0.0074 0.0708 0.0999
Echinococcus multilocularis pyruvate kinase 0.0058 0.0533 0.0533
Brugia malayi hypothetical protein 0.0013 0.0021 0.002
Mycobacterium tuberculosis Conserved protein 0.004 0.0325 0.1012
Echinococcus granulosus flap endonuclease 1 0.0029 0.02 0.0221
Brugia malayi regulator of G-protein signaling egl-10 0.0042 0.0347 0.0481
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0055 0.0499 0.0499
Loa Loa (eye worm) intermediate filament protein 0.003 0.0212 0.0299
Entamoeba histolytica hypothetical protein 0.0189 0.2013 1
Trypanosoma brucei phosphatidylinositol 4-kinase, putative 0.005 0.0436 0.4125
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD3 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.002 0.0104 0.0191
Schistosoma mansoni shc transforming protein 0.0013 0.0023 0.0019
Trichomonas vaginalis PIKK family atypical protein kinase 0.0029 0.0207 0.068
Echinococcus granulosus nuclear receptor nhr 48 0.0049 0.043 0.0475
Trichomonas vaginalis conserved hypothetical protein 0.0047 0.0404 0.1375
Schistosoma mansoni TGF-beta signal transducer Smad2 0.0026 0.0168 0.0191
Mycobacterium tuberculosis Probable hydrolase 0.004 0.0325 0.1012
Plasmodium falciparum LCCL domain-containing protein 0.0022 0.0122 0.0961
Schistosoma mansoni defective proboscis extension response (dpr)-related 0.0013 0.0021 0.0017
Loa Loa (eye worm) pyruvate kinase-PB 0.0051 0.0456 0.0644
Loa Loa (eye worm) hypothetical protein 0.003 0.0212 0.0299
Schistosoma mansoni proto-oncogene tyrosine-protein kinase abl1 0.0017 0.0068 0.0073
Echinococcus granulosus death domain containing protein 0.0014 0.0033 0.0037
Brugia malayi intermediate filament protein 0.003 0.0212 0.0291
Mycobacterium tuberculosis Conserved protein 0.004 0.0325 0.1012
Echinococcus granulosus aryl hydrocarbon receptor 0.0287 0.3114 0.3439
Brugia malayi Variant SH3 domain containing protein 0.0013 0.0023 0.0023
Loa Loa (eye worm) hypothetical protein 0.0049 0.043 0.0607
Echinococcus granulosus importin subunit beta 1 0.0035 0.0268 0.0297
Onchocerca volvulus 0.0019 0.0084 0.0253
Trypanosoma cruzi hypothetical protein, conserved 0.004 0.0325 0.3039
Echinococcus multilocularis tyrosine protein kinase Srms 0.005 0.0441 0.0441
Trichomonas vaginalis PIKK family atypical protein kinase 0.0037 0.0293 0.0982
Trypanosoma brucei target of rapamycin kinase 3, putative 0.004 0.0322 0.3012
Echinococcus multilocularis growth factor receptor bound protein 2 0.0017 0.0068 0.0068
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0019 0.0084 0.0245
Echinococcus granulosus intermediate filament protein 0.003 0.0212 0.0234
Brugia malayi Intermediate filament tail domain containing protein 0.003 0.0212 0.0291
Brugia malayi tRNA modification GTPase TrmE family protein 0.0013 0.0023 0.0023
Mycobacterium ulcerans acyl-CoA synthetase 0.0029 0.0199 0.1103
Onchocerca volvulus 0.0134 0.1393 0.448
Echinococcus multilocularis tyrosyl DNA phosphodiesterase 1 0.0073 0.07 0.07
Echinococcus granulosus lipoxygenase domain containing protein 0.0022 0.0122 0.0134
Mycobacterium tuberculosis Probable oxidoreductase 0.0133 0.1372 0.4898
Mycobacterium ulcerans epimerase 0.0022 0.0127 0.0564
Trypanosoma brucei GTP-binding nuclear protein rtb2, putative 0.0026 0.0165 0.1478
Schistosoma mansoni smad1 5 8 and 0.0026 0.0168 0.0191
Trichomonas vaginalis DNA helicase recq, putative 0.0013 0.0018 0.0008
Schistosoma mansoni hypothetical protein 0.0045 0.0384 0.0445
Loa Loa (eye worm) hypothetical protein 0.0057 0.0522 0.0736
Schistosoma mansoni microtubule-associated protein tau 0.0763 0.8491 1
Loa Loa (eye worm) MaxiK calcium-activated potassium channel 0.003 0.0219 0.0309
Loa Loa (eye worm) hypothetical protein 0.0049 0.043 0.0607
Loa Loa (eye worm) hypothetical protein 0.0021 0.0117 0.0165
Mycobacterium tuberculosis Probable membrane NADH dehydrogenase NdhA 0.0119 0.1222 0.4341
Loa Loa (eye worm) G protein signaling regulator EGL-10 0.0042 0.0347 0.0489
Echinococcus multilocularis tyrosine protein kinase lyn lyn a protein tyrosine kinase lymphocyte specific protein tyrosine kinase 0.0054 0.0487 0.0487
Brugia malayi Papain family cysteine protease containing protein 0.0019 0.0084 0.0111
Echinococcus multilocularis proto oncogene tyrosine protein kinase LCK 0.0054 0.0487 0.0487
Trichomonas vaginalis guanylate cyclase, putative 0.0047 0.0404 0.1375
Echinococcus multilocularis cysteine protease 0.0019 0.0084 0.0084
Trypanosoma cruzi phosphatidylinositol 3-related kinase, putative 0.0017 0.0064 0.0493
Loa Loa (eye worm) hypothetical protein 0.0104 0.1051 0.1483
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0034 0.0256 0.0294
Toxoplasma gondii glucose-6-phosphate 1-dehydrogenase 0.0112 0.1143 1
Echinococcus granulosus tyrosine protein kinase Src64B 0.0054 0.0487 0.0538
Mycobacterium tuberculosis Probable pyruvate kinase PykA 0.0074 0.0708 0.2435
Loa Loa (eye worm) CYP4Cod1 0.0025 0.0161 0.0228
Chlamydia trachomatis endonuclease IV 0.0085 0.0832 0.784
Echinococcus multilocularis ankyrin repeat and death domain containing protein 0.0014 0.0033 0.0033
Brugia malayi Tyrosyl-DNA phosphodiesterase family protein 0.0073 0.07 0.0979
Echinococcus granulosus tyrosine protein kinase Lyn 0.0055 0.0493 0.0544
Toxoplasma gondii isocitrate dehydrogenase 0.0017 0.0073 0.0528
Echinococcus granulosus mothers against decapentaplegic 2 0.0012 0.0006 0.0007
Echinococcus granulosus A kinase anchor protein 10 mitochondrial 0.0042 0.0347 0.0383
Echinococcus multilocularis basic fibroblast growth factor receptor 1 A 0.0114 0.1161 0.1161
Schistosoma mansoni pyruvate kinase 0.0074 0.0708 0.0828
Entamoeba histolytica Flap nuclease, putative 0.0029 0.02 0.0927
Mycobacterium tuberculosis Conserved protein 0.004 0.0325 0.1012
Schistosoma mansoni retinoblastoma-binding protein 4 (rbbp4) 0.0014 0.0034 0.0033
Loa Loa (eye worm) hypothetical protein 0.0262 0.2828 0.399
Entamoeba histolytica acyl-CoA synthetase, putative 0.0029 0.0199 0.0918
Schistosoma mansoni nuclear hormone receptor 0.0049 0.043 0.05
Echinococcus granulosus tyrosine kinase|tyrosine protein kinase Fyn 0.005 0.0441 0.0487
Schistosoma mansoni signal transduction protein lnk-related 0.0013 0.0023 0.0019
Trichomonas vaginalis PIKK family atypical protein kinase 0.003 0.0211 0.0691
Echinococcus granulosus insulin growth factor 1 receptor beta 0.0057 0.0514 0.0568
Trichomonas vaginalis 6-phosphogluconolactonase, putative 0.0112 0.1143 0.3992
Trichomonas vaginalis pyruvate kinase, putative 0.0074 0.0708 0.2453
Trypanosoma cruzi cysteine peptidase, putative 0.0071 0.0672 0.6418
Loa Loa (eye worm) hypothetical protein 0.0016 0.0058 0.0081
Schistosoma mansoni cpg binding protein 0.0034 0.0254 0.0293
Echinococcus multilocularis FTZ F1 alpha 0.0104 0.1051 0.1051
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0104 0.1051 0.1161
Echinococcus granulosus phosphatidylinositol 3 and 4 kinase 0.0017 0.0064 0.007
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.0104 0.1051 0.1232
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.004 0.0325 0.045
Echinococcus granulosus expressed conserved protein 0.0013 0.0023 0.0025
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0019 0.0084 0.0245
Leishmania major phosphatidylinositol 3-related kinase, putative 0.0017 0.0064 0.0493
Schistosoma mansoni ataxia telangiectasia mutated (atm)-related 0.005 0.0436 0.0507
Echinococcus multilocularis tumor protein p63 0.0702 0.7801 0.7801
Mycobacterium tuberculosis Probable chain -fatty-acid-CoA ligase FadD13 (fatty-acyl-CoA synthetase) 0.0029 0.0199 0.0544
Loa Loa (eye worm) variant SH3 domain-containing protein 0.0017 0.0068 0.0097
Schistosoma mansoni loxhd1 0.0022 0.0122 0.0136
Trypanosoma brucei trypanothione reductase 0.0052 0.0466 0.441
Echinococcus granulosus arachidonate 5 lipoxygenase 0.013 0.1348 0.1489
Giardia lamblia GTOR 0.005 0.0436 0.3353
Schistosoma mansoni tyrosine kinase 0.0093 0.092 0.1077
Brugia malayi hypothetical protein 0.0028 0.019 0.026
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD5 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.002 0.0104 0.0191
Mycobacterium tuberculosis Probable dehydrogenase 0.0119 0.1222 0.4341
Brugia malayi cathepsin L-like precursor 0.0012 0.0015 0.0013
Loa Loa (eye worm) hypothetical protein 0.0013 0.0023 0.0032
Trichomonas vaginalis PIKK family atypical protein kinase 0.0017 0.0064 0.0171
Loa Loa (eye worm) nuclear receptor NHR-67 0.0049 0.043 0.0607
Brugia malayi RNA, U transporter 1 0.0099 0.0993 0.1394
Onchocerca volvulus Pyruvate kinase homolog 0.0074 0.0708 0.2269
Loa Loa (eye worm) hypothetical protein 0.0213 0.2284 0.3222
Leishmania major 4-coumarate:coa ligase-like protein 0.0029 0.0199 0.1809
Schistosoma mansoni axis inhibition protein axin 0.0042 0.0347 0.0401
Echinococcus granulosus RUN 0.0022 0.0122 0.0134
Plasmodium falciparum apurinic/apyrimidinic endonuclease Apn1, putative 0.0085 0.0832 0.7249
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0018 0.008 0.0653
Entamoeba histolytica acyl-CoA synthetase, putative 0.0029 0.0199 0.0918
Mycobacterium ulcerans cytochrome P450 185A4 Cyp185A4 0.0025 0.0161 0.0823
Trichomonas vaginalis PIKK family atypical protein kinase 0.004 0.0322 0.1084
Onchocerca volvulus 0.0286 0.3102 1
Loa Loa (eye worm) hypothetical protein 0.0021 0.0117 0.0165
Echinococcus granulosus Mitotic checkpoint protein PRCC C terminal 0.0139 0.1447 0.1598
Onchocerca volvulus 0.0013 0.0023 0.0053
Echinococcus multilocularis 0.0016 0.0052 0.0052
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.0104 0.1051 0.1161
Leishmania major cathepsin L-like protease 0.0019 0.0084 0.0697
Leishmania major mitogen activated protein kinase 4, putative;with=GeneDB:LmxM19.1440 0.0056 0.0512 0.4857
Schistosoma mansoni phosphatidylinositol 3-and 4-kinase 0.0017 0.0064 0.0068
Brugia malayi bHLH-PAS transcription factor 0.0133 0.1381 0.1941
Echinococcus granulosus NCK adaptor protein 0.0017 0.0068 0.0076
Echinococcus granulosus c src tyrosine kinase 0.0022 0.0123 0.0136
Loa Loa (eye worm) TK/FER protein kinase 0.0018 0.0077 0.0109
Echinococcus multilocularis thioredoxin glutathione reductase 0.0052 0.0466 0.0466
Loa Loa (eye worm) hypothetical protein 0.0055 0.0497 0.0701
Brugia malayi Variant SH3 domain containing protein 0.0013 0.0023 0.0023
Leishmania major isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0017 0.0073 0.0582
Echinococcus granulosus GTP binding nuclear protein Ran 0.0026 0.0165 0.0182
Mycobacterium tuberculosis Putative ferredoxin reductase 0.0119 0.1222 0.4341
Onchocerca volvulus 0.004 0.0325 0.103
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD2 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0029 0.0199 0.111
Schistosoma mansoni growth factor receptor-bound protein 0.0017 0.0068 0.0073
Entamoeba histolytica phosphatidylinositol3-kinaseTor2, putative 0.005 0.0436 0.2108
Schistosoma mansoni tyrosine kinase 0.0018 0.0077 0.0084
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0017 0.0073 0.0073
Onchocerca volvulus 0.0053 0.0478 0.1523
Echinococcus multilocularis Niemann Pick C1 protein 0.0109 0.1105 0.1105
Loa Loa (eye worm) hypothetical protein 0.0042 0.0347 0.0489
Brugia malayi Uncoordinated protein 44 0.0014 0.0033 0.0038
Loa Loa (eye worm) GTP-binding nuclear protein RAN/TC4 0.0026 0.0165 0.0232
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0018 0.008 0.0653
Schistosoma mansoni single-minded 0.018 0.1909 0.2243
Echinococcus multilocularis lipoxygenase domain containing protein 0.0022 0.0122 0.0122
Echinococcus multilocularis mothers against decapentaplegic 5 0.0026 0.0168 0.0168
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0019 0.0084 0.0245
Echinococcus granulosus potassium large conductance calcium activated 0.0046 0.0393 0.0434
Plasmodium vivax dihydrolipoyl dehydrogenase, apicoplast, putative 0.0018 0.008 0.0593
Treponema pallidum glucose-6-phosphate 1-dehydrogenase 0.0103 0.104 1
Mycobacterium ulcerans putative regulatory protein 0.0133 0.1381 1
Loa Loa (eye worm) hypothetical protein 0.0014 0.0033 0.0047
Echinococcus granulosus ankyrin repeat and death domain containing protein 0.0014 0.0033 0.0037
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0049 0.043 0.137
Trypanosoma cruzi trypanothione reductase, putative 0.0052 0.0466 0.441
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0034 0.0256 0.0294
Plasmodium vivax apurinic/apyrimidinic endonuclease Apn1, putative 0.0085 0.0832 0.7249
Schistosoma mansoni tar DNA-binding protein 0.007 0.0666 0.0778
Loa Loa (eye worm) nuclear receptor nhr-7B 0.0049 0.043 0.0607
Mycobacterium tuberculosis Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB 0.0119 0.1222 0.4341
Echinococcus multilocularis transfer RNA-Lys 0.0133 0.1381 0.1381
Echinococcus granulosus pyruvate kinase 0.0038 0.0303 0.0335
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0019 0.0084 0.0119
Loa Loa (eye worm) hypothetical protein 0.0035 0.0268 0.0379
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.004 0.0325 0.0458
Schistosoma mansoni tyrosine kinase 0.0057 0.0514 0.0599
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0019 0.0084 0.0245
Trichomonas vaginalis adenylate cyclase, type VII, putative 0.0047 0.0404 0.1375
Brugia malayi Regulator of G protein signaling domain containing protein 0.0042 0.0347 0.0481
Brugia malayi Nuclear hormone receptor-like 1 0.0055 0.0497 0.0693
Mycobacterium leprae conserved hypothetical protein 0.0022 0.0127 0.0568
Echinococcus multilocularis pyruvate kinase 0.0074 0.0708 0.0708
Trypanosoma cruzi hypothetical protein, conserved 0.004 0.0325 0.3039
Leishmania major cathepsin L-like protease 0.0019 0.0084 0.0697
Entamoeba histolytica cysteine proteinase, putative 0.0019 0.0084 0.0346
Brugia malayi Protein-tyrosine phosphatase containing protein 0.0013 0.0023 0.0023
Trichomonas vaginalis CMGC family protein kinase 0.0056 0.0512 0.1756
Echinococcus multilocularis sterol regulatory element binding protein 0.0047 0.0403 0.0403
Echinococcus multilocularis dnaJ subfamily B 0.0452 0.4982 0.4982
Brugia malayi hypoxia-induced factor 1 0.0167 0.1755 0.247
Loa Loa (eye worm) TK/ABL protein kinase 0.0018 0.0077 0.0109
Schistosoma mansoni proto-oncogene tyrosine-protein kinase src 0.0022 0.0123 0.0138
Echinococcus granulosus pyruvate kinase 0.0074 0.0708 0.0782
Loa Loa (eye worm) AGC/GRK/GRK protein kinase 0.0042 0.0352 0.0497
Brugia malayi Doublecortin family protein 0.0022 0.0122 0.0163
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0019 0.0084 0.0245
Trichomonas vaginalis conserved hypothetical protein 0.0042 0.0347 0.1173
Loa Loa (eye worm) transcription factor SMAD2 0.038 0.4168 0.5881
Echinococcus multilocularis c src tyrosine kinase 0.0022 0.0123 0.0123
Trypanosoma brucei phosphatidylinositol 3-kinase tor, putative 0.0024 0.0141 0.1245
Schistosoma mansoni axis inhibition protein axin 0.0042 0.0347 0.0401
Echinococcus granulosus SH2 motif 0.0013 0.0023 0.0025
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0019 0.0084 0.0245
Echinococcus multilocularis mitogen activated protein kinase 0.0056 0.0512 0.0512
Brugia malayi hypothetical protein 0.0049 0.043 0.0599
Echinococcus multilocularis pyruvate kinase 0.0038 0.0303 0.0303
Plasmodium vivax vivapain-2 0.0019 0.0084 0.0633
Loa Loa (eye worm) aryl Hydrocarbon receptor Associated protein family member 0.0048 0.0416 0.0587
Mycobacterium tuberculosis NAD(P)H quinone reductase LpdA 0.0133 0.1372 0.4898
Loa Loa (eye worm) hypothetical protein 0.0013 0.0023 0.0032
Loa Loa (eye worm) hypothetical protein 0.0012 0.0015 0.0022
Loa Loa (eye worm) STAT protein 0.0184 0.1956 0.2759
Trichomonas vaginalis PIKK family atypical protein kinase 0.0017 0.0064 0.0171
Trichomonas vaginalis DNA helicase recq, putative 0.0024 0.0142 0.0448
Schistosoma mansoni lamin 0.003 0.0212 0.0243
Brugia malayi nuclear hormone receptor 0.0049 0.043 0.0599
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0055 0.0499 0.0499
Echinococcus granulosus pyruvate kinase 0.0074 0.0708 0.0782
Giardia lamblia Glucose-6-phosphate 1-dehydrogenase 0.0112 0.1143 1
Echinococcus multilocularis tyrosine kinase 0.0018 0.0077 0.0077
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0104 0.1051 0.1232
Schistosoma mansoni glucose-6-phosphate 1-dehydrogenase 0.0103 0.104 0.1218
Schistosoma mansoni tensin 0.0013 0.0023 0.0019
Trypanosoma cruzi STE group serine/threonine-protein kinase, putative 0.0047 0.041 0.3864
Loa Loa (eye worm) hypothetical protein 0.0042 0.0347 0.0489
Loa Loa (eye worm) hypothetical protein 0.0049 0.043 0.0607
Loa Loa (eye worm) hypothetical protein 0.0017 0.0068 0.0097
Mycobacterium ulcerans aldehyde dehydrogenase 0.0067 0.0633 0.4377
Trichomonas vaginalis mercuric reductase, putative 0.0018 0.008 0.0229
Echinococcus multilocularis musashi 0.003 0.0212 0.0212
Brugia malayi SH2 domain containing protein 0.0013 0.0023 0.0023
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0017 0.0073 0.0073
Loa Loa (eye worm) Smad1 0.0026 0.0168 0.0237
Echinococcus multilocularis ecdysone induced protein 78C 0.0104 0.1051 0.1051
Echinococcus multilocularis TGF beta signal transducer SmadC 0.0026 0.0168 0.0168
Echinococcus granulosus regulator of G protein signaling 7 0.0042 0.0347 0.0383
Schistosoma mansoni thyroid hormone receptor 0.0243 0.2623 0.3084
Echinococcus granulosus netrin receptor unc 5 0.0014 0.0033 0.0037
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0055 0.0497 0.0578
Trichomonas vaginalis CMGC family protein kinase 0.0056 0.0512 0.1756
Leishmania major aldehyde dehydrogenase, mitochondrial precursor 0.0067 0.0633 0.6044
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.0016 0.0053 0.0358
Echinococcus granulosus tyrosine protein kinase Src42A 0.0054 0.0487 0.0538
Loa Loa (eye worm) hypothetical protein 0.0013 0.0023 0.0032
Trichomonas vaginalis PIKK family atypical protein kinase 0.0037 0.0293 0.0982
Schistosoma mansoni lipoxygenase 0.013 0.1348 0.1581
Loa Loa (eye worm) hypothetical protein 0.0016 0.0058 0.0081
Echinococcus granulosus expressed conserved protein 0.0102 0.103 0.1138
Echinococcus granulosus thyroid hormone receptor alpha 0.0049 0.043 0.0475
Brugia malayi Pyruvate kinase, alpha/beta domain containing protein 0.0022 0.0127 0.0171
Onchocerca volvulus Cathepsin F homolog 0.0019 0.0084 0.0253
Echinococcus granulosus mothers against decapentaplegic 6 0.0012 0.0006 0.0007
Trypanosoma cruzi trypanothione reductase, putative 0.0018 0.008 0.0653
Leishmania major target of rapamycin (TOR) kinase 2, putative 0.005 0.0436 0.4125
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0054 0.0487 0.0487
Trichomonas vaginalis adenylate cyclase, putative 0.0047 0.0404 0.1375
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0055 0.0499 0.0581
Brugia malayi nuclear hormone receptor family member nhr-6 0.0049 0.043 0.0599
Trypanosoma brucei isocitrate dehydrogenase, putative 0.0017 0.0073 0.0582
Trichomonas vaginalis CMGC family protein kinase 0.0056 0.0512 0.1756
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.004 0.0325 0.0376
Loa Loa (eye worm) hypothetical protein 0.0014 0.0034 0.0049
Schistosoma mansoni hypothetical protein 0.0372 0.4072 0.4792
Leishmania major importin beta-1 subunit, putative 0.0028 0.0194 0.1765
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.004 0.0325 0.0376
Echinococcus multilocularis tensin 0.0013 0.0023 0.0023
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0029 0.0199 0.1103
Plasmodium vivax isocitrate dehydrogenase [NADP], mitochondrial, putative 0.0017 0.0073 0.0528
Schistosoma mansoni hypothetical protein 0.0205 0.2186 0.2569
Echinococcus multilocularis SH2 motif 0.0013 0.0023 0.0023
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0055 0.0499 0.0704
Echinococcus granulosus epidermal growth factor receptor 0.0169 0.1781 0.1968
Leishmania major ATP-dependent DEAD/H DNA helicase recQ, putative 0.0013 0.0018 0.0047
Entamoeba histolytica acyl-coA synthetase, putative 0.0029 0.0199 0.0918
Mycobacterium ulcerans hypothetical protein 0.0029 0.0199 0.1103
Echinococcus granulosus beta-adrenergic receptor kinase 0.0042 0.0352 0.0389
Trichomonas vaginalis conserved hypothetical protein 0.0047 0.0404 0.1375
Trichomonas vaginalis PIKK family atypical protein kinase 0.0037 0.0293 0.0982
Loa Loa (eye worm) hypothetical protein 0.004 0.0325 0.0458
Brugia malayi AMP-binding enzyme family protein 0.0029 0.0199 0.0272
Plasmodium falciparum glutathione reductase 0.0052 0.0466 0.4006
Trichomonas vaginalis PIKK family atypical protein kinase 0.0017 0.0064 0.0171
Trichomonas vaginalis PIKK family atypical protein kinase 0.0029 0.0207 0.068
Brugia malayi MH2 domain containing protein 0.0026 0.0168 0.0228
Echinococcus multilocularis tyrosine protein kinase Src64B 0.0054 0.0487 0.0487
Brugia malayi hypothetical protein 0.0042 0.0347 0.0481
Plasmodium vivax SET domain protein, putative 0.0034 0.0256 0.215
Trichomonas vaginalis PIKK family atypical protein kinase 0.0027 0.0178 0.0577
Echinococcus granulosus neurotracting:lsamp:neurotrimin:obcam 0.0013 0.0021 0.0023
Echinococcus granulosus tyrosine protein kinase shark 0.0018 0.0078 0.0087
Echinococcus granulosus neuroglian 0.0016 0.0058 0.0064
Leishmania major flap endonuclease-1 (FEN-1), putative 0.0029 0.02 0.1827
Loa Loa (eye worm) TK/KIN16 protein kinase 0.0018 0.0075 0.0106
Echinococcus granulosus retinoic acid receptor rxr beta a 0.0309 0.3364 0.3715
Mycobacterium ulcerans hypothetical protein 0.004 0.0325 0.2054
Echinococcus multilocularis SH2 motif 0.0013 0.0023 0.0023
Brugia malayi Cathepsin L-like precursor 0.0019 0.0084 0.0111
Echinococcus granulosus Ankyrin 0.0014 0.0034 0.0038
Brugia malayi Protein kinase domain containing protein 0.0018 0.0077 0.01
Echinococcus granulosus tyrosine protein kinase Fyn 0.0054 0.0487 0.0538
Brugia malayi Variant SH3 domain containing protein 0.0017 0.0068 0.0088
Loa Loa (eye worm) TK/EGFR protein kinase 0.0169 0.1781 0.2514
Schistosoma mansoni ecdysone-induced protein 78c (dr-78) 0.0055 0.0497 0.0578
Echinococcus multilocularis phosphatidylinositol 3 kinase regulatory subunit 0.0013 0.0023 0.0023
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD35 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.002 0.0104 0.0191
Brugia malayi Isocitrate dehydrogenase 0.0017 0.0073 0.0094
Mycobacterium tuberculosis Probable glucose-6-phosphate 1-dehydrogenase Zwf2 (G6PD) 0.0036 0.0279 0.0843
Trypanosoma brucei phosphatidylinositol 3-kinase, putative 0.0017 0.0064 0.0493
Trichomonas vaginalis PIKK family atypical protein kinase 0.0027 0.0178 0.0577
Brugia malayi RhoGAP domain containing protein 0.0013 0.0023 0.0023
Trichomonas vaginalis DNA helicase recq1, putative 0.0024 0.0142 0.0448
Schistosoma mansoni hypothetical protein 0.0036 0.0287 0.0331
Echinococcus granulosus tyrosine protein kinase Blk 0.005 0.0441 0.0487
Brugia malayi Nuclear hormone receptor E75 0.0049 0.043 0.0599
Mycobacterium ulcerans lipase LipD 0.004 0.0325 0.2054
Echinococcus granulosus tyrosine protein phosphatase non receptor type 0.0013 0.0023 0.0025
Plasmodium vivax glucose-6-phosphate 1-dehydrogenase, putative 0.0112 0.1143 1
Echinococcus multilocularis pyruvate kinase 0.0038 0.0303 0.0303
Brugia malayi cytochrome P450 0.0016 0.0052 0.0065
Entamoeba histolytica Niemann-Pick C1 protein, putative 0.0109 0.1105 0.5453
Schistosoma mansoni tyrosine-protein kinase zap-70 0.0013 0.0023 0.0019
Toxoplasma gondii ABC1 family protein 0.004 0.0325 0.276
Schistosoma mansoni hypothetical protein 0.0189 0.2013 0.2365
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0018 0.008 0.0653
Brugia malayi Cathepsin L-like precursor 0.0019 0.0084 0.0111
Onchocerca volvulus 0.0019 0.0084 0.0253
Onchocerca volvulus 0.003 0.0212 0.0665
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0021 0.0117 0.0488
Brugia malayi SH2 domain containing protein 0.0013 0.0023 0.0023
Trypanosoma cruzi STE/STE11 serine/threonine-protein kinase, putative 0.0047 0.041 0.3864
Loa Loa (eye worm) glucose-6-phosphate dehydrogenase 0.0103 0.104 0.1467
Mycobacterium ulcerans long-chain fatty-acid CoA ligase 0.0029 0.0199 0.1103
Brugia malayi Nuclear hormone receptor-like 1 0.0104 0.1051 0.1476
Trypanosoma cruzi phosphatidylinositol 3-related kinase, putative 0.0017 0.0064 0.0493
Mycobacterium ulcerans aldehyde dehydrogenase 0.0067 0.0633 0.4377
Schistosoma mansoni ran 0.0026 0.0165 0.0187
Onchocerca volvulus 0.0263 0.2842 0.9162
Echinococcus granulosus tyrosine protein kinase Fps85D 0.0018 0.0077 0.0085
Echinococcus multilocularis axis inhibition protein axin 0.0042 0.0347 0.0347
Brugia malayi Death domain containing protein 0.0014 0.0033 0.0038
Brugia malayi Hypothetical 29.7 kDa protein C05D11.5 in chromosome III 0.0022 0.0127 0.0171
Brugia malayi Bloom's syndrome protein homolog 0.0024 0.0142 0.0192
Brugia malayi Cytochrome P450 family protein 0.0025 0.0161 0.0219
Plasmodium falciparum flap endonuclease 1 0.0029 0.02 0.166
Onchocerca volvulus Cathepsin L homolog 0.0019 0.0084 0.0253
Schistosoma mansoni RAR-like nuclear receptor 0.0104 0.1051 0.1232
Schistosoma mansoni nck2/grb4 0.0017 0.0068 0.0073
Brugia malayi SH2 domain containing protein 0.0018 0.0077 0.01
Loa Loa (eye worm) hypothetical protein 0.0014 0.0032 0.0045
Leishmania major cathepsin L-like protease 0.0071 0.0672 0.6418
Trichomonas vaginalis PIKK family atypical protein kinase 0.0032 0.024 0.0794
Loa Loa (eye worm) cytochrome P450 family protein 0.0058 0.0529 0.0746
Brugia malayi Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain containing protein 0.0013 0.0026 0.0028
Echinococcus multilocularis fibroblast growth factor receptor 4 0.0114 0.1161 0.1161
Echinococcus multilocularis arachidonate 5 lipoxygenase 0.013 0.1348 0.1348
Echinococcus granulosus Niemann Pick C1 protein 0.0109 0.1105 0.122
Schistosoma mansoni tensin-related 0.0013 0.0023 0.0019
Loa Loa (eye worm) TAR-binding protein 0.007 0.0666 0.094
Plasmodium falciparum dihydrolipoyl dehydrogenase, apicoplast 0.0018 0.008 0.0593
Giardia lamblia Kinase, CMGC MAPK 0.0056 0.0512 0.4059
Leishmania major mitogen activated protein kinase, putative,map kinase, putative 0.0056 0.0512 0.4857
Onchocerca volvulus Huntingtin homolog 0.0135 0.1405 0.4519
Mycobacterium tuberculosis Possible penicillin-binding protein 0.0254 0.2747 1
Brugia malayi Protein kinase domain containing protein 0.0018 0.0077 0.01
Echinococcus granulosus GPCR family 2 0.0036 0.0287 0.0317
Mycobacterium ulcerans dihydrolipoamide dehydrogenase, LpdB 0.0018 0.008 0.021
Echinococcus granulosus pyruvate kinase 0.0038 0.0303 0.0335
Brugia malayi cytoplasmic intermediate filament protein 0.0016 0.0056 0.007
Loa Loa (eye worm) hypothetical protein 0.0022 0.0122 0.0171
Loa Loa (eye worm) hypothetical protein 0.0021 0.0117 0.0165
Loa Loa (eye worm) hypothetical protein 0.0104 0.1051 0.1483
Loa Loa (eye worm) hypothetical protein 0.0104 0.1051 0.1483
Onchocerca volvulus 0.0104 0.1051 0.3376
Echinococcus granulosus SH2 domain containing protein 7 0.0013 0.0023 0.0025
Loa Loa (eye worm) CXXC zinc finger family protein 0.0032 0.0234 0.033
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0019 0.0084 0.0245
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.0104 0.1051 0.1051
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.0019 0.0084 0.0245
Echinococcus granulosus hypothetical protein 0.0013 0.0023 0.0025
Loa Loa (eye worm) variant SH3 domain-containing protein 0.0013 0.0023 0.0032
Echinococcus multilocularis cpg binding protein 0.0034 0.0254 0.0254
Loa Loa (eye worm) MH2 domain-containing protein 0.0012 0.0006 0.0009
Schistosoma mansoni cathepsin F (C01 family) 0.0019 0.0084 0.0092
Mycobacterium ulcerans esterase/lipase LipP 0.004 0.0325 0.2054
Loa Loa (eye worm) hypothetical protein 0.0012 0.0013 0.0018
Brugia malayi TAR-binding protein 0.007 0.0666 0.0932
Onchocerca volvulus 0.0049 0.043 0.137
Trichomonas vaginalis soluble guanylate cyclase gcy, putative 0.0047 0.0404 0.1375
Loa Loa (eye worm) isocitrate dehydrogenase 0.0017 0.0073 0.0102
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.0104 0.1051 0.1483
Loa Loa (eye worm) TK protein kinase 0.005 0.0441 0.0623
Echinococcus granulosus tyrosine kinase 0.0018 0.0077 0.0085
Loa Loa (eye worm) TK/FER protein kinase 0.0018 0.0077 0.0109
Echinococcus multilocularis netrin receptor unc 5 0.0014 0.0033 0.0033
Leishmania major 4-coumarate:coa ligase-like protein 0.0029 0.0199 0.1809
Mycobacterium ulcerans pyruvate kinase 0.0074 0.0708 0.494
Loa Loa (eye worm) SH2 domain-containing protein 0.0013 0.0023 0.0032
Plasmodium falciparum cysteine proteinase falcipain 2a 0.0019 0.0084 0.0633
Echinococcus multilocularis cytoplasmic intermediate filament protein 0.0014 0.0038 0.0038
Brugia malayi Cathepsin L-like precursor 0.0012 0.0015 0.0013
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0018 0.008 0.0653
Schistosoma mansoni suppressor of cytokine signaling 0.0013 0.0023 0.0019
Schistosoma mansoni lipoxygenase 0.0091 0.0905 0.1059
Toxoplasma gondii HEAT repeat-containing protein 0.0035 0.0268 0.2261
Entamoeba histolytica Ran family GTPase 0.0026 0.0165 0.0748
Trypanosoma cruzi glucose-6-phosphate 1-dehydrogenase, putative 0.0103 0.104 1
Schistosoma mansoni nuclear hormone receptor superfamily protein-related 0.0049 0.043 0.05
Entamoeba histolytica hypothetical protein 0.0042 0.0347 0.1659
Schistosoma mansoni dihydrolipoamide dehydrogenase 0.0018 0.008 0.0087
Echinococcus multilocularis FKBP12 rapamycin complex associated protein 0.005 0.0436 0.0436
Leishmania major trypanothione reductase 0.0052 0.0466 0.441
Echinococcus granulosus defective proboscis extension response 0.0013 0.0021 0.0023
Echinococcus multilocularis protein patched 0.0047 0.0403 0.0403
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0019 0.0084 0.0245
Loa Loa (eye worm) hypothetical protein 0.0049 0.043 0.0607
Echinococcus multilocularis regulator of G protein signaling 0.0042 0.0347 0.0347
Schistosoma mansoni blooms syndrome DNA helicase 0.0019 0.0086 0.0094
Plasmodium vivax pyruvate kinase 2, putative 0.0038 0.0303 0.2566
Loa Loa (eye worm) nuclear hormone receptor-like 1 0.0055 0.0497 0.0701
Loa Loa (eye worm) pyruvate kinase 0.0074 0.0708 0.0999
Brugia malayi Large-conductance calcium-activated potassium channel Slo-1 (KCNMA) alpha subunit. C. elegans slo-1 ortholog 0.003 0.0219 0.0301
Brugia malayi Probable G protein-coupled receptor kinase F19C6.1, putative 0.0042 0.0352 0.0489
Toxoplasma gondii LsmAD domain-containing protein 0.0028 0.019 0.1567
Echinococcus granulosus twitchin 0.0017 0.0063 0.007
Brugia malayi nuclear receptor NHR-88 0.0104 0.1051 0.1476
Brugia malayi nuclear receptor RXR 0.0049 0.043 0.0599
Schistosoma mansoni hypothetical protein 0.0114 0.1167 0.1368
Echinococcus granulosus lipoxygenase domain containing protein 0.0022 0.0122 0.0134
Plasmodium vivax acyl-CoA synthetase, putative 0.0021 0.0117 0.092
Schistosoma mansoni hypothetical protein 0.0016 0.0052 0.0054
Toxoplasma gondii GTP-binding nuclear protein ran/tc4 0.0026 0.0165 0.1343
Brugia malayi A-kinase anchor protein 10, precursor 0.0042 0.0347 0.0481
Entamoeba histolytica hypothetical protein 0.0189 0.2013 1
Onchocerca volvulus 0.0049 0.043 0.137
Plasmodium falciparum isocitrate dehydrogenase [NADP], mitochondrial 0.0017 0.0073 0.0528
Trichomonas vaginalis conserved hypothetical protein 0.0047 0.0404 0.1375
Echinococcus multilocularis tyrosine protein kinase Src42A 0.0054 0.0487 0.0487
Echinococcus granulosus signal transduction protein lnk realted 0.0013 0.0023 0.0025
Loa Loa (eye worm) RecQ helicase 0.0024 0.0142 0.02
Loa Loa (eye worm) hypothetical protein 0.0022 0.0122 0.0171
Onchocerca volvulus 0.0019 0.0084 0.0253
Echinococcus granulosus Ataxin 2 N terminaldomain containing protein 0.0013 0.0017 0.0018
Loa Loa (eye worm) hypothetical protein 0.0012 0.0006 0.0009
Trichomonas vaginalis regulator of G protein signaling 5, rgs5, putative 0.0042 0.0347 0.1173
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0104 0.1051 0.1051
Loa Loa (eye worm) hypothetical protein 0.0034 0.0256 0.0361
Schistosoma mansoni pyruvate kinase 0.0074 0.0708 0.0828
Loa Loa (eye worm) hypothetical protein 0.0055 0.0497 0.0701
Loa Loa (eye worm) hypothetical protein 0.0029 0.0199 0.028
Trypanosoma brucei cytochrome P450, putative 0.0025 0.0161 0.1447
Echinococcus granulosus mitogen activated protein kinase 0.0056 0.0512 0.0565
Echinococcus granulosus regulator of G protein signaling 3 0.0042 0.0347 0.0383
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0019 0.0084 0.0245
Plasmodium falciparum acyl-CoA synthetase 0.0021 0.0117 0.092
Echinococcus multilocularis nuclear factor of activated T cells 5 0.0072 0.0683 0.0683
Mycobacterium leprae Possible regulatory protein 0.0047 0.0404 0.2665
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.0104 0.1051 0.1483
Echinococcus multilocularis signal transduction protein lnk realted 0.0013 0.0023 0.0023
Echinococcus multilocularis GTP binding nuclear protein Ran 0.0026 0.0165 0.0165
Trichomonas vaginalis PIKK family atypical protein kinase 0.0013 0.0026 0.0038
Echinococcus multilocularis mothers against decapentaplegic 6 0.0012 0.0006 0.0006
Loa Loa (eye worm) hypothetical protein 0.0049 0.043 0.0607
Echinococcus multilocularis tyrosine protein kinase lyn tyrosine protein kinase blk 0.0054 0.0487 0.0487
Brugia malayi Cathepsin L-like cysteine proteinase 0.0012 0.0015 0.0013
Echinococcus granulosus cytochrome P450 2K1 0.0016 0.0052 0.0058
Entamoeba histolytica protein kinase, putative 0.0037 0.0294 0.1395
Trichomonas vaginalis adenylate and guanylate cyclases, putative 0.0047 0.0404 0.1375
Loa Loa (eye worm) hypothetical protein 0.0055 0.0497 0.0701
Loa Loa (eye worm) hypothetical protein 0.0013 0.0023 0.0032
Echinococcus granulosus microtubule associated protein 2 0.0763 0.8491 0.9379
Loa Loa (eye worm) TK/FER protein kinase 0.0018 0.0077 0.0109
Trichomonas vaginalis PIKK family atypical protein kinase 0.0037 0.0293 0.0982
Echinococcus multilocularis SH2 domain containing adapter protein F 0.0013 0.0023 0.0023
Brugia malayi Cathepsin L-like precursor 0.0019 0.0084 0.0111
Loa Loa (eye worm) cytochrome P450 0.0016 0.0052 0.0074
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0019 0.0084 0.0245
Brugia malayi isocitrate dehydrogenase 0.0017 0.0073 0.0094
Echinococcus multilocularis Smad4 0.0026 0.0168 0.0168
Echinococcus multilocularis roundabout 2 0.0016 0.0058 0.0058
Schistosoma mansoni patched 1 0.0047 0.0403 0.0468
Loa Loa (eye worm) hypothetical protein 0.0019 0.0084 0.0119
Brugia malayi Cathepsin L-like precursor 0.0019 0.0084 0.0111
Loa Loa (eye worm) hypothetical protein 0.004 0.0325 0.0458
Echinococcus multilocularis geminin 0.0205 0.2186 0.2186
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0034 0.0256 0.215
Brugia malayi nuclear receptor NHR-88 0.0049 0.043 0.0599
Schistosoma mansoni tyrosine kinase 0.0054 0.0487 0.0567
Loa Loa (eye worm) beta-lactamase 0.004 0.0325 0.0458
Loa Loa (eye worm) hypothetical protein 0.004 0.0325 0.0458
Echinococcus multilocularis nuclear receptor nhr 48 0.0049 0.043 0.043
Brugia malayi Steroid receptor seven-up type 2 0.0104 0.1051 0.1476
Loa Loa (eye worm) hypothetical protein 0.0104 0.1051 0.1483
Trypanosoma cruzi cytochrome p450-like protein, putative 0.0016 0.0052 0.0382
Trichomonas vaginalis PIKK family atypical protein kinase 0.0027 0.0178 0.0577
Trypanosoma cruzi Phosphatidylinositol 3-kinase tor2 0.005 0.0436 0.4125
Leishmania major phosphatidylinositol 3-kinase, putative 0.0017 0.0064 0.0493
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0049 0.043 0.043
Loa Loa (eye worm) hypothetical protein 0.004 0.0325 0.0458
Plasmodium vivax multidomain scavenger receptor, putative 0.0022 0.0122 0.0961
Plasmodium vivax thioredoxin reductase, putative 0.0052 0.0466 0.4006
Onchocerca volvulus 0.0018 0.0077 0.023
Echinococcus granulosus SH2 domain containing adapter protein F 0.0013 0.0023 0.0025
Loa Loa (eye worm) hypothetical protein 0.024 0.2585 0.3648
Chlamydia trachomatis pyruvate kinase 0.0074 0.0708 0.6548
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0104 0.1051 0.1476
Schistosoma mansoni tyrosine kinase 0.0088 0.0865 0.1013
Loa Loa (eye worm) cytochrome P450 family protein 0.0025 0.0161 0.0228
Loa Loa (eye worm) abnormal chemotaxis protein 14 0.0047 0.0403 0.0568
Mycobacterium tuberculosis Probable lipase LipD 0.004 0.0325 0.1012
Trypanosoma cruzi Lanosterol 14-alpha demethylase 0.0016 0.0052 0.0382
Plasmodium vivax hypothetical protein, conserved 0.004 0.0325 0.276
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.0104 0.1051 0.1232
Trypanosoma cruzi major cysteine proteinase, putative 0.0055 0.0501 0.4758
Schistosoma mansoni hypothetical protein 0.0045 0.0384 0.0445
Schistosoma mansoni cellular tumor antigen P53 0.0103 0.1035 0.1213
Loa Loa (eye worm) hypothetical protein 0.0286 0.3102 0.4376
Brugia malayi protein-tyrosine kinase 0.005 0.0441 0.0615
Brugia malayi MH1 domain containing protein 0.0026 0.0168 0.0228
Loa Loa (eye worm) hypothetical protein 0.0029 0.0199 0.028
Loa Loa (eye worm) hypothetical protein 0.0013 0.0021 0.0029
Onchocerca volvulus 0.003 0.0212 0.0665
Mycobacterium ulcerans acyl-CoA synthetase 0.0029 0.0199 0.1103
Echinococcus multilocularis cathepsin l cysteine peptidase 0.0019 0.0084 0.0084
Onchocerca volvulus Suppressor of cytokine signaling 7 homolog 0.0013 0.0023 0.0053
Schistosoma mansoni cytochrome P450 0.0016 0.0052 0.0054
Echinococcus granulosus guanine nucleotide exchange factor VAV2 0.0013 0.0023 0.0025
Toxoplasma gondii CMGC kinase, MAPK family (ERK) MAPK-1 0.0056 0.0512 0.4411
Echinococcus granulosus tyrosine protein kinase Srms 0.0018 0.0077 0.0085
Brugia malayi AMP-binding enzyme family protein 0.0029 0.0199 0.0272
Loa Loa (eye worm) hypothetical protein 0.0049 0.043 0.0607
Brugia malayi SH2 domain containing protein 0.0013 0.0023 0.0023
Echinococcus granulosus transcription factor Dp 1 0.0042 0.0352 0.0389
Echinococcus multilocularis SHC transforming protein 3 0.0013 0.0023 0.0023
Echinococcus multilocularis tyrosine protein kinase HCK 0.0037 0.0294 0.0294
Echinococcus granulosus tensin 0.0013 0.0023 0.0025
Trypanosoma brucei tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0073 0.07 0.6688
Echinococcus granulosus 3'partial|tyrosine protein kinase Fgr 0.0054 0.0487 0.0538
Trichomonas vaginalis PIKK family atypical protein kinase 0.0027 0.0178 0.0577
Schistosoma mansoni tyrosine kinase 0.0088 0.0865 0.1013
Echinococcus multilocularis 0.0013 0.0023 0.0023
Loa Loa (eye worm) RNA binding protein 0.007 0.0666 0.094
Trypanosoma brucei dihydrolipoamide dehydrogenase, point mutation 0.0018 0.008 0.0653
Echinococcus multilocularis tyrosine protein kinase Src42A 0.0045 0.0387 0.0387
Echinococcus multilocularis microtubule associated protein 2 0.0763 0.8491 0.8491
Loa Loa (eye worm) hypothetical protein 0.0239 0.2573 0.3631
Echinococcus multilocularis A kinase anchor protein 10, mitochondrial 0.0042 0.0347 0.0347
Brugia malayi beta-lactamase 0.004 0.0325 0.045
Entamoeba histolytica hypothetical protein 0.0189 0.2013 1
Brugia malayi Nuclear hormone receptor-like 1 0.0055 0.0497 0.0693
Onchocerca volvulus 0.0018 0.0077 0.023
Brugia malayi MH1 domain containing protein 0.0014 0.0037 0.0044
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.0019 0.0084 0.0245
Loa Loa (eye worm) hypothetical protein 0.0042 0.0347 0.0489
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0071 0.0672 0.6418
Chlamydia trachomatis two component regulatory system sensor histidine kinase 0.0047 0.0404 0.3375
Onchocerca volvulus 0.004 0.0325 0.103
Schistosoma mansoni regulator of G protein signaling 0.0042 0.0347 0.0401
Schistosoma mansoni smad1 5 8 and 0.0026 0.0168 0.0191
Trypanosoma cruzi cruzipain precursor, putative 0.0071 0.0672 0.6418
Trypanosoma cruzi target of rapamycin kinase 3 0.004 0.0322 0.3012
Brugia malayi GTP-binding nuclear protein RAN/TC4 0.0026 0.0165 0.0224
Trypanosoma cruzi pyruvate kinase 2, putative 0.0074 0.0708 0.6773
Schistosoma mansoni suppressor of cytokine signaling 0.0013 0.0023 0.0019
Echinococcus granulosus Polycystic kidney disease protein 0.0022 0.0122 0.0134
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0019 0.0084 0.0245
Echinococcus multilocularis cysteine protease 0.0019 0.0084 0.0084
Onchocerca volvulus 0.0018 0.0077 0.023
Brugia malayi Nuclear hormone receptor family member nhr-31 0.0104 0.1051 0.1476
Echinococcus granulosus FKBP12 rapamycin complex associated protein 0.005 0.0436 0.0482
Plasmodium vivax vivapain-2 0.0019 0.0084 0.0633
Trypanosoma cruzi ATP-dependent DEAD/H DNA helicase recQ, putative 0.0013 0.0018 0.0047
Trichomonas vaginalis importin beta-1, putative 0.0028 0.0194 0.0633
Entamoeba histolytica SH2-protein kinase domain containing protein 0.0018 0.0077 0.031
Echinococcus multilocularis lamin dm0 0.003 0.0212 0.0212
Schistosoma mansoni z-protein (S1r protein) 0.0042 0.0347 0.0401
Schistosoma mansoni netrin receptor unc5 0.0014 0.0033 0.0032
Brugia malayi Tensin 0.0013 0.0023 0.0023
Entamoeba histolytica tyrosyl-DNA phosphodiesterase, putative 0.0073 0.07 0.3426
Schistosoma mansoni hypothetical protein 0.0013 0.0023 0.0019
Schistosoma mansoni importin beta-1 0.0035 0.0268 0.0309
Loa Loa (eye worm) hypothetical protein 0.0013 0.0023 0.0032
Onchocerca volvulus 0.0019 0.0084 0.0253
Trichomonas vaginalis PIKK family atypical protein kinase 0.003 0.0211 0.0691
Echinococcus granulosus lamin dm0 0.003 0.0212 0.0234
Brugia malayi SH2 domain containing protein 0.0013 0.0023 0.0023
Schistosoma mansoni GTPase activating protein 0.0013 0.0023 0.0019
Leishmania major pyruvate kinase 0.0074 0.0708 0.6773
Schistosoma mansoni nephrin 0.0016 0.0058 0.0061
Brugia malayi Thioredoxin reductase 0.0052 0.0466 0.0649
Loa Loa (eye worm) hypothetical protein 0.0013 0.0023 0.0032
Trichomonas vaginalis conserved hypothetical protein 0.0042 0.0347 0.1173
Echinococcus multilocularis basement membrane specific heparan sulfate 0.0013 0.0021 0.0021
Plasmodium falciparum pyruvate kinase 0.0074 0.0708 0.6152
Loa Loa (eye worm) flap endonuclease-1 0.0029 0.02 0.0283
Schistosoma mansoni regulator of G protein signaling 17 19 20 (rgs17 19 20) 0.0042 0.0347 0.0401
Leishmania major cytochrome p450-like protein 0.0025 0.0161 0.1447
Entamoeba histolytica hypothetical protein 0.0028 0.0194 0.0895
Schistosoma mansoni growth factor receptor-bound protein 0.0017 0.0068 0.0073
Loa Loa (eye worm) hypothetical protein 0.0013 0.0023 0.0032
Entamoeba histolytica hypothetical protein 0.0189 0.2013 1
Toxoplasma gondii endonuclease IV APN 0.0085 0.0832 0.7249
Trypanosoma cruzi Lanosterol 14-alpha demethylase 0.0016 0.0052 0.0382
Loa Loa (eye worm) hypothetical protein 0.0018 0.0077 0.0109
Schistosoma mansoni cell adhesion molecule 0.0013 0.0021 0.0017
Onchocerca volvulus 0.0022 0.0122 0.0373
Echinococcus granulosus nuclear receptor subfamily 1 group D 0.0055 0.0497 0.0548
Schistosoma mansoni nuclear hormone receptor 0.0049 0.043 0.05
Echinococcus multilocularis tar DNA binding protein 0.007 0.0666 0.0666
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.0026 0.0165 0.1478
Onchocerca volvulus 0.0034 0.0256 0.0807
Plasmodium vivax pyruvate kinase, putative 0.0074 0.0708 0.6152
Echinococcus multilocularis tensin 0.0013 0.0023 0.0023
Plasmodium falciparum glutathione reductase 0.0018 0.008 0.0593
Schistosoma mansoni cathepsin F (C01 family) 0.0019 0.0084 0.0092
Trypanosoma brucei PAB1-binding protein , putative 0.0028 0.019 0.1726
Onchocerca volvulus Putative hydroxypyruvate isomerase 0.0022 0.0127 0.0391
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.0104 0.1051 0.1051
Loa Loa (eye worm) hypothetical protein 0.0049 0.043 0.0607
Echinococcus multilocularis glucose 6 phosphate 1 dehydrogenase 0.0103 0.104 0.104
Plasmodium falciparum thioredoxin reductase 0.0052 0.0466 0.4006
Echinococcus multilocularis lipoxygenase domain containing protein 0.0022 0.0122 0.0122
Trichomonas vaginalis PIKK family atypical protein kinase 0.0027 0.0178 0.0575
Trypanosoma cruzi flap endonuclease-1 (FEN-1), putative 0.0029 0.02 0.1827
Leishmania major lanosterol 14-alpha-demethylase, putative 0.0016 0.0052 0.0382
Echinococcus multilocularis insulin receptor 0.0057 0.0514 0.0514
Leishmania major pyruvate kinase 0.0074 0.0708 0.6773
Loa Loa (eye worm) hypothetical protein 0.0013 0.0021 0.0029
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0056 0.0512 0.4857
Echinococcus granulosus regulator of G protein signaling 3 0.0042 0.0347 0.0383
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0034 0.0256 0.0256
Echinococcus granulosus tar DNA binding protein 0.007 0.0666 0.0736
Brugia malayi tailless protein 0.0049 0.043 0.0599
Echinococcus multilocularis beta LACTamase domain containing family member 0.004 0.0325 0.0325
Brugia malayi MH1 domain containing protein 0.0014 0.0037 0.0044
Brugia malayi SH2 domain containing protein 0.0013 0.0023 0.0023
Loa Loa (eye worm) hypothetical protein 0.0013 0.0023 0.0032
Entamoeba histolytica cysteine protease, putative 0.0019 0.0084 0.0346
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0019 0.0084 0.0245
Onchocerca volvulus Cathepsin L homolog 0.0019 0.0084 0.0253
Loa Loa (eye worm) glutathione reductase 0.0052 0.0466 0.0657
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0104 0.1051 0.1476
Loa Loa (eye worm) hypothetical protein 0.0013 0.0023 0.0032
Schistosoma mansoni tyrosine kinase 0.0114 0.1161 0.1361
Wolbachia endosymbiont of Brugia malayi dihydrolipoamide dehydrogenase E3 component 0.0018 0.008 0.5
Echinococcus granulosus nuclear receptor subfamily 4 group A 0.0049 0.043 0.0475
Brugia malayi regulator of G-protein signaling rgs-7 0.0042 0.0347 0.0481
Loa Loa (eye worm) hypothetical protein 0.0042 0.0347 0.0489
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0019 0.0084 0.0245
Plasmodium vivax ataxin-2 like protein, putative 0.0028 0.019 0.1567
Loa Loa (eye worm) hypothetical protein 0.0013 0.0021 0.0029
Brugia malayi hypothetical protein 0.0213 0.2284 0.3217
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0071 0.0672 0.6418
Trichomonas vaginalis PIKK family atypical protein kinase 0.0027 0.0178 0.0575
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0019 0.0084 0.0245
Echinococcus granulosus TGF beta signal transducer SmadC 0.0026 0.0168 0.0185
Echinococcus multilocularis isocitrate dehydrogenase 2 (NADP+) 0.0017 0.0073 0.0073
Brugia malayi Protein kinase domain containing protein 0.0014 0.0039 0.0046
Loa Loa (eye worm) cytochrome P450 family protein 0.0025 0.0161 0.0228
Mycobacterium ulcerans endonuclease IV 0.0085 0.0832 0.5874
Loa Loa (eye worm) hypothetical protein 0.0029 0.0199 0.028
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0231 0.2482 0.3502
Brugia malayi hypothetical protein 0.0135 0.1405 0.1976
Trypanosoma brucei FAT domain/Rapamycin binding domain/Phosphatidylinositol 3- and 4-kinase, putative 0.0021 0.0108 0.093
Echinococcus granulosus tyrosine protein phosphatase non receptor type 0.0013 0.0023 0.0025
Toxoplasma gondii aldehyde dehydrogenase 0.0067 0.0633 0.549
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.0104 0.1051 0.1051
Brugia malayi SH2 domain containing protein 0.0018 0.0077 0.01
Loa Loa (eye worm) thioredoxin reductase 0.0052 0.0466 0.0657
Mycobacterium ulcerans glucose-6-phosphate 1-dehydrogenase 0.0067 0.0636 0.4394
Schistosoma mansoni nuclear receptor 0.0049 0.043 0.05
Loa Loa (eye worm) SH2 domain-containing protein 0.0013 0.0023 0.0032
Schistosoma mansoni coup transcription factor 0.0104 0.1051 0.1232
Trichomonas vaginalis PIKK family atypical protein kinase 0.0017 0.0064 0.0171
Mycobacterium leprae Probable lipase LipE 0.004 0.0325 0.2066
Entamoeba histolytica SH2 domain containing protein 0.0013 0.0023 0.0037
Trichomonas vaginalis guanylate cyclase, putative 0.0047 0.0404 0.1375
Brugia malayi small heat shock protein 0.0639 0.7087 1
Echinococcus multilocularis cathepsin l cysteine peptidase 0.0019 0.0084 0.0084
Echinococcus granulosus Smad4 0.0026 0.0168 0.0185
Schistosoma mansoni ran 0.0026 0.0165 0.0187
Schistosoma mansoni Neurotrimin precursor (hNT) 0.0013 0.0021 0.0017
Trypanosoma brucei Phosphatidylinositol 3-kinase tor1 0.005 0.0436 0.4125
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0019 0.0084 0.0245
Mycobacterium tuberculosis Fatty-acid-AMP ligase FadD30 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) 0.0021 0.0117 0.024
Loa Loa (eye worm) TK protein kinase 0.0117 0.1198 0.169
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0018 0.008 0.0653
Brugia malayi Nuclear hormone receptor family member nhr-1 0.0104 0.1051 0.1476
Echinococcus multilocularis Ataxin 2, N terminal,domain containing protein 0.0013 0.0017 0.0017
Loa Loa (eye worm) hypothetical protein 0.0022 0.0127 0.0179
Loa Loa (eye worm) hypothetical protein 0.0021 0.0117 0.0165
Schistosoma mansoni polycystin 1-related 0.0022 0.0122 0.0136
Brugia malayi Protein kinase domain containing protein 0.0018 0.0077 0.01
Leishmania major protein kinase, putative 0.0047 0.041 0.3864
Loa Loa (eye worm) fibroinase 0.0019 0.0084 0.0119
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0019 0.0084 0.0245

Activities

Activity type Activity value Assay description Source Reference
Potency (functional) 7.3078 uM PUBCHEM_BIOASSAY: qHTS Assay for Inhibitors of RanGTP induced Rango (Ran-regulated importin-beta cargo) - Importin beta complex dissociation. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID540262] ChEMBL. No reference
Potency (functional) 11.2202 uM PubChem BioAssay. A quantitative high throughput screen for small molecules that induce DNA re-replication in MCF 10a normal breast cells. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) 11.2202 uM PubChem BioAssay. qHTS for Agonist of gsp, the Etiologic Mutation Responsible for Fibrous Dysplasia/McCune-Albright Syndrome: qHTS. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) = 14.1254 um PUBCHEM_BIOASSAY: qHTS for inhibitors of ROR gamma transcriptional activity. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) 15.1014 uM PUBCHEM_BIOASSAY: qHTS profiling assay for firefly luciferase inhibitor/activator using purified enzyme and Km concentrations of substrates (counterscreen for miR-21 project). (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID2288, AID2289, AID2598, AID411] ChEMBL. No reference
Potency (functional) 19.9526 uM PubChem BioAssay. qHTS of PTHR Inhibitors: Primary Screen. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) = 22.3872 um PUBCHEM_BIOASSAY: qHTS Fluorescence Polarization Assay for Inhibitors of MLL CXXC domain - DNA interaction. (Class of assay: confirmatory) [Related pubchem assays: 2698 (Summary assay.)] ChEMBL. No reference
Potency (functional) = 22.3872 um PUBCHEM_BIOASSAY: qHTS Assay for Inhibitors Targeting the Menin-MLL Interaction in MLL Related Leukemias: Competition With Texas Red Labeled MLL-derived Mutant Peptide. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) 22.3872 uM PubChem BioAssay. qHTS for Inhibitors of Glutaminase (GLS). (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) 29.081 uM PUBCHEM_BIOASSAY: qHTS screen for small molecules that inhibit ELG1-dependent DNA repair in human embryonic kidney (HEK293T) cells expressing luciferase-tagged ELG1. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID493107, AID493125] ChEMBL. No reference
Potency (functional) 29.0929 uM PubChem BioAssay. A quantitative high throughput screen for small molecules that induce DNA re-replication in SW480 colon adenocarcinoma cells. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) = 39.8107 um PUBCHEM_BIOASSAY: qHTS Assay for Inhibitors of Aldehyde Dehydrogenase 1 (ALDH1A1). (Class of assay: confirmatory) [Related pubchem assays: 1030 (qHTS Validation Assay for Inhibitors of aldehyde dehydrogenase 1 (ALDH1A1))] ChEMBL. No reference
Potency (functional) 50.1187 uM PubChem BioAssay. qHTS for Antagonists of gsp, the Etiologic Mutation Responsible for Fibrous Dysplasia/McCune-Albright Syndrome: qHTS. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) 89.1251 uM PUBCHEM_BIOASSAY: qHTS Assay for Inhibitors of Histone Lysine Methyltransferase G9a. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID504404] ChEMBL. No reference
Potency (functional) = 100 um PUBCHEM_BIOASSAY: qHTS Assay for Inhibitors of DNA Polymerase Beta. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) 112.2018 uM PUBCHEM_BIOASSAY: qHTS Assay for Inhibitors of Rango (Ran-regulated importin-beta cargo) - Importin beta complex formation. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID540273] ChEMBL. No reference

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

Bibliographic References

No literature references available for this target.

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