Detailed information for compound 139034

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 217.181 | Formula: C10H7N3O3
  • H donors: 1 H acceptors: 4 LogP: 0.8 Rotable bonds: 1
    Rule of 5 violations (Lipinski): 1
  • SMILES: COc1ccc2c(c1)c(O)c1c(o2)nnn1
  • InChi: 1S/C10H7N3O3/c1-15-5-2-3-7-6(4-5)9(14)8-10(16-7)12-13-11-8/h2-4,14H,1H3
  • InChiKey: MZICZJQNVNYJKE-UHFFFAOYSA-N  


Substructure search Similarity search

Network

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0025 0.0059 0.0495
Trypanosoma brucei Inositol phosphosphingolipids phospholipase C 0.0015 0.0018 0.0058
Echinococcus granulosus tumor protein p63 0.0356 0.1425 0.2632
Loa Loa (eye worm) hypothetical protein 0.0077 0.0274 0.0505
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0292 0.116 0.5696
Trichomonas vaginalis Clan SC, family S9, acylaminoacyl-peptidase-like serine peptidase 0.0014 0.0014 0.0029
Schistosoma mansoni hypothetical protein 0.0033 0.0092 0.017
Trypanosoma cruzi oligopeptidase b 0.0054 0.0179 0.0319
Mycobacterium leprae PROBABLE HYDROLASE 0.0056 0.0185 0.3204
Brugia malayi Heterochromatin protein 1 0.0033 0.0093 0.0171
Schistosoma mansoni cellular tumor antigen P53 0.0052 0.0171 0.0315
Brugia malayi Valyl-tRNA synthetase 0.0033 0.0093 0.0171
Echinococcus multilocularis inhibitor of apoptosis protein 0.0053 0.0172 0.0172
Brugia malayi G protein-coupled receptor F59B2.13 0.0033 0.0092 0.017
Loa Loa (eye worm) hypothetical protein 0.0033 0.0092 0.017
Loa Loa (eye worm) glutamate receptor 1 0.007 0.0242 0.0448
Leishmania major 4-coumarate:coa ligase-like protein 0.0025 0.0059 0.0261
Echinococcus multilocularis neuropeptides capa receptor 0.0033 0.0092 0.0092
Onchocerca volvulus 0.0033 0.0092 0.0486
Echinococcus granulosus orexin receptor type 2 0.0033 0.0092 0.017
Echinococcus multilocularis lamin 0.0026 0.0065 0.0065
Onchocerca volvulus 0.0033 0.0093 0.0491
Loa Loa (eye worm) hypothetical protein 0.0067 0.0233 0.043
Brugia malayi ImpB/MucB/SamB family protein 0.0039 0.0117 0.0217
Plasmodium falciparum importin beta, putative 0.0032 0.0086 0.043
Trypanosoma brucei Dipeptidyl-peptidase 8-like, putative 0.0014 0.0014 0.0043
Trypanosoma cruzi DNA polymerase eta, putative 0.0039 0.0117 0.0206
Echinococcus granulosus rhodopsin orphan GPCR 0.0033 0.0092 0.017
Onchocerca volvulus 0.0033 0.0092 0.0486
Schistosoma mansoni Lysine-specific histone demethylase 1 0.0071 0.0249 0.046
Leishmania major trypanothione reductase 0.0037 0.0108 0.0507
Mycobacterium ulcerans flavin-containing monoamine oxidase AofH 0.0014 0.0015 0.0088
Trypanosoma brucei importin beta-1 subunit, putative 0.0032 0.0086 0.0395
Entamoeba histolytica cysteine protease, putative 0.0203 0.0792 0.4205
Toxoplasma gondii 'chromo' (CHRromatin Organization MOdifier) domain-containing protein 0.0033 0.0093 0.043
Brugia malayi hypothetical protein 0.0033 0.0092 0.017
Plasmodium falciparum serine repeat antigen 4 0.0136 0.0515 0.274
Trichomonas vaginalis Heterochromatin protein, putative 0.0033 0.0093 0.0417
Trypanosoma cruzi cysteine protease, putative 0.0203 0.0792 0.1454
Trichomonas vaginalis DNA polymerase eta, putative 0.0039 0.0117 0.0538
Schistosoma mansoni chromobox protein 0.0033 0.0093 0.0171
Entamoeba histolytica cysteine protease, putative 0.0203 0.0792 0.4205
Loa Loa (eye worm) CCR4-NOT transcription complex subunit 6 family protein 0.0015 0.0018 0.0032
Giardia lamblia Hypothetical protein 0.0136 0.0515 0.2516
Mycobacterium ulcerans flavoprotein disulfide reductase 0.0013 0.0009 0.0026
Leishmania major cathepsin L-like protease 0.0463 0.1864 0.918
Echinococcus granulosus dro:myosuppressin receptor 0.0033 0.0092 0.017
Brugia malayi MH2 domain containing protein 0.0116 0.0432 0.0798
Brugia malayi gonadotropin-releasing hormone receptor 2 0.0033 0.0092 0.017
Schistosoma mansoni chromobox protein 0.0033 0.0093 0.0171
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0033 0.0092 0.017
Trichomonas vaginalis carbon catabolite repressor protein, putative 0.0015 0.0018 0.0045
Brugia malayi prolyl oligopeptidase family protein 0.0014 0.0014 0.0027
Schistosoma mansoni subfamily C1A unassigned peptidase (C01 family) 0.0136 0.0515 0.0951
Trypanosoma brucei prolyl oligopeptidase, putative 0.0054 0.0179 0.0853
Onchocerca volvulus Matrix metalloproteinase homolog 0.0101 0.0373 0.1993
Entamoeba histolytica cysteine protease, putative 0.0136 0.0515 0.2707
Onchocerca volvulus Heterochromatin protein 1 homolog 0.0033 0.0093 0.0491
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0013 0.0009 0.0005
Schistosoma mansoni amine GPCR 0.0033 0.0092 0.017
Mycobacterium ulcerans fructose-bisphosphate aldolase 0.0143 0.0544 0.5031
Trypanosoma brucei DNA polymerase kappa, putative 0.0039 0.0117 0.0551
Loa Loa (eye worm) O-glycosyl hydrolase family 30 protein 0.0254 0.1002 0.1852
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0013 0.0009 0.0005
Echinococcus granulosus 7tm_1 domain containing protein 0.0033 0.0092 0.017
Plasmodium falciparum protoporphyrinogen oxidase 0.0014 0.0015 0.0051
Leishmania major hypothetical protein, conserved 0.0015 0.0018 0.0058
Brugia malayi prolyl oligopeptidase family protein 0.0014 0.0014 0.0027
Schistosoma mansoni thyrotropin-releasing hormone receptor 0.0033 0.0092 0.017
Schistosoma mansoni neutral sphingomyelinase 0.0015 0.0018 0.0032
Plasmodium vivax vivapain-2 0.0463 0.1864 1
Giardia lamblia Alanyl dipeptidyl peptidase 0.0014 0.0014 0.0043
Mycobacterium tuberculosis Probable hydrolase 0.0039 0.0118 0.1027
Echinococcus granulosus neuropeptide receptor 0.0033 0.0092 0.017
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0463 0.1864 0.9179
Schistosoma mansoni hypothetical protein 0.0033 0.0092 0.017
Loa Loa (eye worm) MH2 domain-containing protein 0.0116 0.0432 0.0798
Mycobacterium tuberculosis Probable dehydrogenase 0.0085 0.0304 0.2772
Echinococcus multilocularis dna polymerase kappa 0.0039 0.0117 0.0117
Loa Loa (eye worm) endonuclease/Exonuclease/phosphatase 0.0015 0.0018 0.0032
Echinococcus granulosus tm gpcr rhodopsin 0.0033 0.0092 0.017
Echinococcus multilocularis synaptojanin 1 0.0015 0.0018 0.0018
Schistosoma mansoni ran 0.0023 0.0051 0.0095
Loa Loa (eye worm) hypothetical protein 0.0398 0.1595 0.2947
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0463 0.1864 0.918
Giardia lamblia DINP protein human, muc B family 0.0039 0.0117 0.0551
Echinococcus granulosus CCR4 NOT transcription complex subunit 6 0.0015 0.0018 0.0032
Mycobacterium tuberculosis Putative ferredoxin reductase 0.0085 0.0304 0.2772
Onchocerca volvulus 0.0463 0.1864 1
Entamoeba histolytica inositol polyphosphate 5-phosphatase, putative 0.0015 0.0018 0.0017
Echinococcus multilocularis protoporphyrinogen oxidase 0.0014 0.0015 0.0015
Loa Loa (eye worm) hypothetical protein 0.0039 0.0118 0.0218
Echinococcus multilocularis thyrotropin releasing hormone receptor 0.0033 0.0092 0.0092
Echinococcus multilocularis lysine specific histone demethylase 1A 0.0071 0.0249 0.0249
Plasmodium vivax endonuclease/exonuclease/phosphatase domain containing protein 0.0015 0.0018 0.0063
Schistosoma mansoni hypothetical protein 0.0337 0.1345 0.2485
Schistosoma mansoni glutamate receptor AMPA 0.0026 0.0062 0.0115
Leishmania major hypothetical protein, conserved 0.0015 0.0018 0.0058
Giardia lamblia GTP-binding nuclear protein RAN/TC4 0.0023 0.0051 0.0225
Schistosoma mansoni sex comb on midleg homolog 0.0048 0.0155 0.0287
Onchocerca volvulus 0.0033 0.0092 0.0486
Echinococcus granulosus cathepsin b 0.1324 0.5413 1
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0136 0.0515 0.2505
Loa Loa (eye worm) G-protein-linked acetylcholine receptor protein 2 0.0033 0.0092 0.017
Toxoplasma gondii acylaminoacyl-peptidase, putative 0.0014 0.0014 0.0043
Trichomonas vaginalis chromobox protein, putative 0.0033 0.0093 0.0417
Echinococcus multilocularis sex peptide receptor 0.0033 0.0092 0.0092
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0463 0.1864 0.9179
Schistosoma mansoni opsin-like receptor 0.0033 0.0092 0.017
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.1324 0.5413 1
Loa Loa (eye worm) glutamate receptor 2 0.0026 0.0062 0.0115
Trichomonas vaginalis chromobox protein, putative 0.0033 0.0093 0.0417
Entamoeba histolytica cysteine protease, putative 0.0203 0.0792 0.4205
Loa Loa (eye worm) hypothetical protein 0.0033 0.0092 0.017
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0013 0.0009 0.0005
Echinococcus multilocularis g protein coupled receptor 0.0033 0.0092 0.0092
Loa Loa (eye worm) hypothetical protein 0.0396 0.1587 0.2931
Brugia malayi Dopamine receptor protein 1, putative (partial) 0.0033 0.0092 0.017
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0136 0.0515 0.0951
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0033 0.0092 0.017
Mycobacterium tuberculosis Probable membrane NADH dehydrogenase NdhA 0.0085 0.0304 0.2772
Trichomonas vaginalis carbon catabolite repressor protein, putative 0.0015 0.0018 0.0045
Loa Loa (eye worm) hypothetical protein 0.0136 0.0515 0.0951
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0463 0.1864 0.9179
Brugia malayi polk-prov protein 0.0012 0.0006 0.0011
Leishmania major DNA polymerase kappa, putative 0.0039 0.0117 0.0551
Entamoeba histolytica endonuclease/exonuclease/phosphatase domain containing protein 0.0015 0.0018 0.0017
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0136 0.0515 0.0951
Entamoeba histolytica cysteine protease, putative 0.0136 0.0515 0.2707
Plasmodium falciparum thioredoxin reductase 0.0037 0.0108 0.0553
Loa Loa (eye worm) hypothetical protein 0.0033 0.0092 0.017
Echinococcus granulosus glutamate receptor 2 0.0074 0.0263 0.0485
Loa Loa (eye worm) hypothetical protein 0.0033 0.0092 0.017
Entamoeba histolytica endonuclease/exonuclease/phosphatase family protein 0.0015 0.0018 0.0017
Schistosoma mansoni hypothetical protein 0.0126 0.0474 0.0876
Brugia malayi CCR4 0.0015 0.0018 0.0032
Onchocerca volvulus Matrilysin homolog 0.0101 0.0373 0.1993
Entamoeba histolytica endonuclease/exonuclease/phosphatase family protein 0.0015 0.0018 0.0017
Schistosoma mansoni subfamily C1A unassigned peptidase (C01 family) 0.0136 0.0515 0.0951
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0463 0.1864 0.9179
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0463 0.1864 0.9179
Trypanosoma cruzi hypothetical protein, conserved 0.0014 0.0014 0.0016
Loa Loa (eye worm) prolyl oligopeptidase 0.0014 0.0014 0.0027
Chlamydia trachomatis protoporphyrinogen oxidase 0.0014 0.0015 0.0757
Plasmodium vivax unspecified product 0.0136 0.0515 0.274
Schistosoma mansoni inhibitor of apoptosis (iap) domain family member 0.0053 0.0172 0.0318
Schistosoma mansoni Protoporphyrinogen oxidase chloroplast/mitochondrial precursor 0.0014 0.0015 0.0028
Loa Loa (eye worm) hypothetical protein 0.1324 0.5413 1
Plasmodium vivax hypothetical protein, conserved 0.0015 0.0018 0.0063
Loa Loa (eye worm) cytochrome P450 family protein 0.0049 0.0156 0.0288
Schistosoma mansoni hypothetical protein 0.0126 0.0474 0.0876
Schistosoma mansoni glutamate receptor AMPA 0.0026 0.0062 0.0115
Loa Loa (eye worm) hypothetical protein 0.0033 0.0092 0.017
Onchocerca volvulus 0.0015 0.0018 0.0087
Plasmodium falciparum dihydrolipoyl dehydrogenase, apicoplast 0.0013 0.0009 0.0015
Echinococcus multilocularis endonuclease exonuclease phosphatase 0.0206 0.0804 0.0804
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0292 0.116 0.5696
Trypanosoma brucei DNA polymerase kappa, putative 0.0039 0.0117 0.0551
Plasmodium falciparum lysine-specific histone demethylase 1, putative 0.0014 0.0015 0.0051
Brugia malayi ORL1-like opioid receptor 0.0033 0.0092 0.017
Echinococcus multilocularis fmrfamide receptor 0.0033 0.0092 0.0092
Schistosoma mansoni neuropeptide receptor 0.0033 0.0092 0.017
Loa Loa (eye worm) hypothetical protein 0.0033 0.0092 0.017
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0463 0.1864 0.9179
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.0015 0.0018 0.0022
Echinococcus granulosus neuropeptides capa receptor 0.0033 0.0092 0.017
Schistosoma mansoni ATP-binding cassette transporter 0.0026 0.0062 0.0115
Trypanosoma brucei DNA polymerase kappa, putative 0.0039 0.0117 0.0551
Loa Loa (eye worm) CYP4Cod1 0.0019 0.0035 0.0065
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0463 0.1864 0.918
Echinococcus multilocularis chromodomain helicase DNA binding protein 1 0.0033 0.0093 0.0093
Brugia malayi Papain family cysteine protease containing protein 0.0463 0.1864 0.3443
Entamoeba histolytica cysteine protease, putative 0.0136 0.0515 0.2707
Echinococcus multilocularis pyruvate kinase 0.0027 0.0066 0.0066
Mycobacterium tuberculosis Conserved protein 0.0039 0.0118 0.1027
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0019 0.0033 0.0251
Giardia lamblia Cathepsin L precursor 0.0136 0.0515 0.2516
Giardia lamblia Hypothetical protein 0.0136 0.0515 0.2516
Loa Loa (eye worm) nucleolar RNA-associated protein alpha 0.0337 0.1345 0.2485
Loa Loa (eye worm) ImpB/MucB/SamB family protein 0.0039 0.0117 0.0217
Trichomonas vaginalis Clan CA, family C1, cathepsin L, S or H-like cysteine peptidase 0.0136 0.0515 0.2505
Trypanosoma brucei DNA polymerase kappa, putative 0.0039 0.0117 0.0551
Schistosoma mansoni cpg binding protein 0.003 0.0078 0.0145
Toxoplasma gondii cathepsin CPC1 0.0136 0.0515 0.2516
Schistosoma mansoni muscarinic acetylcholine (GAR) receptor 0.0033 0.0092 0.017
Loa Loa (eye worm) pyruvate kinase-PB 0.0024 0.0053 0.0099
Plasmodium vivax protoporphyrinogen oxidase, putative 0.0014 0.0015 0.0051
Brugia malayi neuropeptide F receptor 0.0033 0.0092 0.017
Schistosoma mansoni hypothetical protein 0.0033 0.0093 0.0171
Brugia malayi Dopamine receptor protein 1 0.0033 0.0092 0.017
Echinococcus granulosus histone acetyltransferase MYST2 0.0055 0.0183 0.0338
Mycobacterium tuberculosis Probable peptidase 0.0054 0.0179 0.1593
Onchocerca volvulus 0.0033 0.0092 0.0486
Echinococcus multilocularis g protein coupled receptor 0.0033 0.0092 0.0092
Trichomonas vaginalis pyruvate kinase, putative 0.0034 0.0096 0.0432
Entamoeba histolytica acyl-CoA synthetase, putative 0.0025 0.0059 0.0239
Schistosoma mansoni synaptojanin 0.0015 0.0018 0.0032
Echinococcus granulosus cytoplasmic intermediate filament protein 0.0013 0.0008 0.0015
Echinococcus multilocularis cathepsin L cysteine protease 0.0463 0.1864 0.1864
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0013 0.0009 0.0005
Echinococcus granulosus prolyl endopeptidase 0.0136 0.0516 0.0954
Leishmania major hypothetical protein, conserved 0.0039 0.0118 0.0555
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0292 0.116 0.5696
Mycobacterium tuberculosis Probable fructose-bisphosphate aldolase Fba 0.0143 0.0544 0.5018
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0136 0.0515 0.2505
Brugia malayi mbt repeat family protein 0.0048 0.0155 0.0287
Brugia malayi Cathepsin L-like precursor 0.0067 0.0233 0.043
Trypanosoma brucei cytochrome P450, putative 0.0019 0.0035 0.0145
Plasmodium vivax hypothetical protein, conserved 0.0039 0.0118 0.0605
Entamoeba histolytica cysteine protease, putative 0.0203 0.0792 0.4205
Leishmania major cytochrome p450-like protein 0.0019 0.0035 0.0145
Echinococcus multilocularis chromobox protein 2 0.0571 0.2307 0.2307
Echinococcus multilocularis neuropeptide receptor 0.0033 0.0092 0.0092
Brugia malayi Associated with TFs and helicases family protein 0.0033 0.0093 0.0171
Wolbachia endosymbiont of Brugia malayi exonuclease III 0.0074 0.0263 1
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0463 0.1864 0.9179
Leishmania major acetoin dehydrogenase e3 component-like protein 0.0013 0.0009 0.0014
Loa Loa (eye worm) hypothetical protein 0.0033 0.0093 0.0171
Loa Loa (eye worm) hypothetical protein 0.0019 0.0033 0.006
Loa Loa (eye worm) hypothetical protein 0.0012 0.0006 0.0011
Schistosoma mansoni hypothetical protein 0.0678 0.2749 0.5078
Echinococcus multilocularis cysteine protease 0.0463 0.1864 0.1864
Schistosoma mansoni cathepsin F (C01 family) 0.0396 0.1587 0.2931
Echinococcus granulosus endonuclease exonuclease phosphatase 0.0206 0.0804 0.1485
Toxoplasma gondii cathepsin B 0.0503 0.203 1
Schistosoma mansoni cathepsin F (C01 family) 0.0463 0.1864 0.3443
Loa Loa (eye worm) matrixin family protein 0.011 0.041 0.0758
Loa Loa (eye worm) cathepsin B 0.0503 0.203 0.375
Brugia malayi hypothetical protein 0.0033 0.0092 0.017
Loa Loa (eye worm) hypothetical protein 0.0071 0.0249 0.046
Brugia malayi Inhibitor of Apoptosis domain containing protein 0.0053 0.0172 0.0318
Giardia lamblia Cathepsin L precursor 0.0136 0.0515 0.2516
Loa Loa (eye worm) cysteine proteinase cathepsin Z 0.0136 0.0515 0.0951
Trichomonas vaginalis glucosylceramidase, putative 0.0167 0.0642 0.3136
Echinococcus granulosus rhodopsin orphan GPCR 0.0033 0.0092 0.017
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0033 0.0092 0.017
Echinococcus multilocularis pyroglutamylated rfamide peptide receptor 0.0033 0.0092 0.0092
Echinococcus granulosus Ataxin 2 N terminaldomain containing protein 0.0047 0.0151 0.0278
Loa Loa (eye worm) hypothetical protein 0.0033 0.0092 0.017
Echinococcus granulosus neuropeptide receptor A26 0.0033 0.0092 0.017
Trichomonas vaginalis chromobox protein, putative 0.0033 0.0093 0.0417
Chlamydia trachomatis acylglycerophosphoethanolamine acyltransferase 0.0019 0.0033 0.2754
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0136 0.0515 0.2505
Schistosoma mansoni dipeptidyl-peptidase I (C01 family) 0.0136 0.0515 0.0951
Trypanosoma brucei Endonuclease/Exonuclease/phosphatase family, putative 0.0015 0.0018 0.0058
Trypanosoma brucei DNA polymerase IV, putative 0.0039 0.0117 0.0551
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD7 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0018 0.0028 0.0186
Trichomonas vaginalis chromobox protein, putative 0.0033 0.0093 0.0417
Toxoplasma gondii endonuclease/exonuclease/phosphatase family protein 0.0015 0.0018 0.0058
Entamoeba histolytica endonuclease/exonuclease/phosphatase family protein 0.0015 0.0018 0.0017
Echinococcus multilocularis pyruvate kinase 0.0017 0.0028 0.0028
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0013 0.0009 0.0005
Loa Loa (eye worm) cysteine protease 0.0463 0.1864 0.3443
Loa Loa (eye worm) hypothetical protein 0.0033 0.0092 0.017
Brugia malayi Papain family cysteine protease containing protein 0.0203 0.0792 0.1463
Brugia malayi Matrixin family protein 0.011 0.041 0.0758
Entamoeba histolytica cysteine protease, putative 0.0203 0.0792 0.4205
Leishmania major pantothenate kinase subunit, putative 0.0016 0.0022 0.0079
Echinococcus granulosus tm gpcr rhodopsin 0.0033 0.0092 0.017
Brugia malayi hypothetical protein 0.0033 0.0092 0.017
Brugia malayi G-protein-linked acetylcholine receptor protein 2, putative 0.0033 0.0092 0.017
Trypanosoma brucei Endonuclease/Exonuclease/phosphatase family, putative 0.0015 0.0018 0.0058
Mycobacterium tuberculosis Probable chain -fatty-acid-CoA ligase FadD13 (fatty-acyl-CoA synthetase) 0.0025 0.0059 0.047
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.004 0.0119 0.0547
Brugia malayi Thioredoxin reductase 0.0037 0.0108 0.02
Mycobacterium tuberculosis Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras 0.0094 0.0343 0.3136
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.0292 0.116 0.6194
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0463 0.1864 0.918
Brugia malayi AMP-binding enzyme family protein 0.0025 0.0059 0.0108
Giardia lamblia Inositol 5-phosphatase 4 0.0015 0.0018 0.0058
Trypanosoma cruzi importin beta-1 subunit, putative 0.0026 0.0061 0.0102
Schistosoma mansoni chromodomain helicase DNA binding protein 0.0033 0.0093 0.0171
Echinococcus granulosus chromodomain helicase DNA binding protein 1 0.0033 0.0093 0.0171
Giardia lamblia Cathepsin B precursor 0.0136 0.0515 0.2516
Trypanosoma cruzi Endonuclease/Exonuclease/phosphatase family, putative 0.0015 0.0018 0.0022
Loa Loa (eye worm) MBCTL1 0.0055 0.0183 0.0338
Echinococcus multilocularis pyruvate kinase 0.0034 0.0096 0.0096
Loa Loa (eye worm) hypothetical protein 0.0033 0.0093 0.0171
Trypanosoma brucei DNA polymerase IV, putative 0.0039 0.0117 0.0551
Loa Loa (eye worm) hypothetical protein 0.0056 0.0185 0.0341
Schistosoma mansoni matrix metallopeptidase-7 (M10 family) 0.0046 0.0144 0.0265
Giardia lamblia Alanyl dipeptidyl peptidase 0.0014 0.0014 0.0043
Schistosoma mansoni lamin 0.0026 0.0065 0.0119
Loa Loa (eye worm) hypothetical protein 0.0019 0.0033 0.006
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0072 0.025 0.1197
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0033 0.0093 0.0417
Onchocerca volvulus 0.0025 0.0059 0.0308
Trypanosoma brucei inositol/phosphatidylinositol phosphatase, putative 0.0015 0.0018 0.0058
Loa Loa (eye worm) hypothetical protein 0.0032 0.0086 0.0158
Entamoeba histolytica cysteine proteinase, putative 0.0396 0.1587 0.8501
Brugia malayi Cathepsin L-like precursor 0.0396 0.1587 0.2931
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0292 0.116 0.5696
Loa Loa (eye worm) hypothetical protein 0.0033 0.0092 0.017
Loa Loa (eye worm) TK/ROR protein kinase 0.0017 0.0026 0.0049
Entamoeba histolytica sphingomyelinase C precursor, putative 0.0015 0.0018 0.0017
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0292 0.116 0.5696
Brugia malayi AMP-binding enzyme family protein 0.0025 0.0059 0.0108
Brugia malayi Cathepsin L-like precursor 0.0463 0.1864 0.3443
Toxoplasma gondii endonuclease/exonuclease/phosphatase family protein 0.0015 0.0018 0.0058
Trichomonas vaginalis glucosylceramidase, putative 0.0254 0.1002 0.4917
Onchocerca volvulus 0.0039 0.0118 0.0627
Echinococcus multilocularis polycomb protein SCMH1 0.0048 0.0155 0.0155
Echinococcus multilocularis neuropeptide FF receptor 2 0.0253 0.0997 0.0997
Mycobacterium ulcerans oxidoreductase 0.0014 0.0015 0.0088
Trichomonas vaginalis conserved hypothetical protein 0.0033 0.0093 0.0417
Plasmodium vivax hypothetical protein, conserved 0.0033 0.0093 0.0468
Plasmodium falciparum cysteine repeat modular protein 1 0.0017 0.0026 0.0111
Echinococcus multilocularis allatostatin A receptor 0.0033 0.0092 0.0092
Schistosoma mansoni opsin-like receptor 0.0033 0.0092 0.017
Loa Loa (eye worm) hypothetical protein 0.0067 0.0233 0.043
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0463 0.1864 0.918
Schistosoma mansoni lamin 0.0026 0.0065 0.0119
Trichomonas vaginalis chromobox protein, putative 0.0033 0.0093 0.0417
Brugia malayi hypothetical protein 0.0033 0.0092 0.017
Brugia malayi C2-HC type zinc finger protein C.e-MyT1 0.0055 0.0183 0.0338
Brugia malayi Endonuclease/Exonuclease/phosphatase family protein 0.0015 0.0018 0.0032
Echinococcus granulosus lamin dm0 0.0026 0.0065 0.0119
Giardia lamblia Cysteine protease 0.0136 0.0515 0.2516
Echinococcus granulosus 7TM GPCR rhodopsin 0.0033 0.0092 0.017
Echinococcus multilocularis beta LACTamase domain containing family member 0.0039 0.0118 0.0118
Onchocerca volvulus Dipeptidyl peptidase family member 1 homolog 0.0014 0.0014 0.007
Echinococcus multilocularis peptide (allatostatin:somatostatin) 0.0033 0.0092 0.0092
Onchocerca volvulus Cathepsin L homolog 0.0136 0.0515 0.2758
Trypanosoma cruzi cysteine peptidase, putative 0.0463 0.1864 0.3436
Brugia malayi beta-lactamase family protein 0.0039 0.0118 0.0218
Entamoeba histolytica cysteine protease, putative 0.0203 0.0792 0.4205
Leishmania major endonuclease/exonuclease protein-like protein 0.0015 0.0018 0.0058
Toxoplasma gondii HEAT repeat-containing protein 0.0032 0.0086 0.0395
Mycobacterium ulcerans monoamine oxidase 0.0014 0.0015 0.0088
Echinococcus multilocularis rhodopsin orphan GPCR 0.0033 0.0092 0.0092
Leishmania major hypothetical protein, conserved 0.0015 0.0018 0.0058
Loa Loa (eye worm) hypothetical protein 0.0396 0.1587 0.2931
Schistosoma mansoni pyruvate kinase 0.0034 0.0096 0.0177
Schistosoma mansoni pyruvate kinase 0.0017 0.0028 0.0051
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0033 0.0092 0.0092
Echinococcus multilocularis G protein coupled 5 hydroxytryptamine receptor 0.0033 0.0092 0.0092
Mycobacterium ulcerans lipase LipD 0.0039 0.0118 0.105
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0035 0.0099 0.0447
Trichomonas vaginalis skeletal muscle/kidney enriched inositol 5-phosphatase, putative 0.0015 0.0018 0.0045
Echinococcus granulosus somatostatin receptor 0.0033 0.0092 0.017
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.0074 0.0263 0.0475
Echinococcus granulosus neuropeptide Y receptor 0.0033 0.0092 0.017
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0231 0.0906 0.1674
Brugia malayi O-Glycosyl hydrolase family 30 protein 0.0254 0.1002 0.1852
Echinococcus multilocularis tachykinin peptides receptor 99D 0.0033 0.0092 0.0092
Trypanosoma brucei dihydrolipoyl dehydrogenase 0.0013 0.0009 0.0014
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0136 0.0515 0.2505
Brugia malayi Papain family cysteine protease containing protein 0.0203 0.0792 0.1463
Schistosoma mansoni amine GPCR 0.0033 0.0092 0.017
Trypanosoma cruzi oligopeptidase B-like protein, putative 0.0054 0.0179 0.0319
Mycobacterium tuberculosis NADPH-dependent mycothiol reductase Mtr 0.0037 0.0108 0.0936
Trypanosoma brucei unspecified product 0.0027 0.0067 0.0303
Chlamydia trachomatis pyruvate kinase 0.0034 0.0096 1
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0136 0.0515 0.2505
Echinococcus multilocularis serotonin receptor 0.0033 0.0092 0.0092
Schistosoma mansoni DNA polymerase eta 0.0039 0.0117 0.0217
Loa Loa (eye worm) hypothetical protein 0.0034 0.0096 0.0177
Trypanosoma cruzi cysteine peptidase C (CPC), putative 0.0503 0.203 0.3743
Echinococcus granulosus Glutamate receptor ionotropic kainate 2 0.0031 0.0083 0.0153
Trypanosoma cruzi Endonuclease/Exonuclease/phosphatase family, putative 0.0015 0.0018 0.0022
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0136 0.0515 0.0951
Mycobacterium leprae Probable pyruvate kinase PykA 0.0034 0.0096 0.1527
Schistosoma mansoni cathepsin s 0.0067 0.0233 0.043
Trypanosoma cruzi PAB1-binding protein , putative 0.0106 0.039 0.0711
Mycobacterium tuberculosis Probable aldehyde dehydrogenase 0.0178 0.069 0.6386
Brugia malayi Matrixin family protein 0.0046 0.0144 0.0265
Echinococcus multilocularis neutral sphingomyelinase 0.0015 0.0018 0.0018
Brugia malayi Endonuclease/Exonuclease/phosphatase family protein 0.0015 0.0018 0.0032
Giardia lamblia hypothetical protein 0.0015 0.0018 0.0058
Echinococcus multilocularis dro:myosuppressin receptor 0.0033 0.0092 0.0092
Brugia malayi Pyruvate kinase, M2 isozyme 0.0034 0.0096 0.0177
Trypanosoma cruzi UDP-galactopyranose mutase 0.0014 0.0015 0.0017
Giardia lamblia Cathepsin L precursor 0.0136 0.0515 0.2516
Entamoeba histolytica hypothetical protein 0.0033 0.0093 0.0424
Echinococcus granulosus pyruvate kinase 0.0017 0.0028 0.0051
Schistosoma mansoni aldehyde dehydrogenase 0.0178 0.069 0.1275
Schistosoma mansoni peptide (FMRFamide/neurokinin-3)-like receptor 0.0033 0.0092 0.017
Mycobacterium ulcerans hypothetical protein 0.0039 0.0118 0.105
Schistosoma mansoni ran 0.0023 0.0051 0.0095
Onchocerca volvulus 0.0033 0.0092 0.0486
Schistosoma mansoni biogenic amine (octopamine/dopamine) receptor 0.0033 0.0092 0.017
Echinococcus multilocularis glutamate (NMDA) receptor subunit 0.0026 0.0062 0.0062
Brugia malayi Latrophilin receptor protein 2 0.0126 0.0474 0.0876
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0463 0.1864 0.9179
Toxoplasma gondii cathepsin CPL 0.0463 0.1864 0.918
Trypanosoma brucei DNA-(apurinic or apyrimidinic site) lyase, putative 0.0015 0.0018 0.0058
Schistosoma mansoni biogenic amine (5HT) receptor 0.0033 0.0092 0.017
Entamoeba histolytica cysteine proteinase, putative 0.0203 0.0792 0.4205
Loa Loa (eye worm) hypothetical protein 0.0048 0.0155 0.0287
Plasmodium vivax acyl-CoA synthetase, putative 0.0019 0.0033 0.0144
Trichomonas vaginalis glucosylceramidase, putative 0.0167 0.0642 0.3136
Giardia lamblia Dipeptidyl-peptidase I precursor 0.0136 0.0515 0.2516
Echinococcus multilocularis rhodopsin orphan GPCR 0.0033 0.0092 0.0092
Plasmodium falciparum cysteine proteinase falcipain 2a 0.0463 0.1864 1
Trypanosoma cruzi pyruvate kinase 2, putative 0.0034 0.0096 0.0167
Echinococcus granulosus glutamate receptor 1 0.0044 0.0136 0.025
Schistosoma mansoni hypothetical protein 0.0309 0.123 0.2273
Brugia malayi Tachykinin-like peptides receptor 99D 0.0253 0.0997 0.1843
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0126 0.0474 0.0474
Trypanosoma brucei inositol-1,4,5-trisphosphate (IP3) 5-phosphatase, putative 0.0015 0.0018 0.0058
Plasmodium falciparum thioredoxin reductase 0.0013 0.0009 0.0015
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0039 0.0118 0.0218
Trypanosoma cruzi mitochondrial protein 99, putative 0.0015 0.0018 0.0022
Trichomonas vaginalis conserved hypothetical protein 0.0033 0.0093 0.0417
Onchocerca volvulus Putative neutral sphingomyelinase 0.0015 0.0018 0.0087
Entamoeba histolytica cysteine protease, putative 0.0203 0.0792 0.4205
Trypanosoma brucei inositol-1(or 4)-monophosphatase 1, putative 0.0072 0.025 0.1209
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0136 0.0515 0.2505
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0203 0.0792 0.3885
Entamoeba histolytica cysteine proteinase, putative 0.0203 0.0792 0.4205
Trypanosoma brucei DNA polymerase kappa, putative 0.0039 0.0117 0.0551
Trypanosoma cruzi cysteine peptidase C (CPC), putative 0.1324 0.5413 1
Onchocerca volvulus Matrilysin homolog 0.0046 0.0144 0.0764
Onchocerca volvulus 0.0065 0.0222 0.1186
Brugia malayi hypothetical protein 0.0033 0.0092 0.017
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0034 0.0095 0.0176
Schistosoma mansoni synaptojanin 0.0015 0.0018 0.0032
Mycobacterium ulcerans cytochrome P450 185A4 Cyp185A4 0.0019 0.0035 0.0274
Trypanosoma cruzi RNA-editing complex protein MP100, putative 0.0015 0.0018 0.0022
Brugia malayi RNA, U transporter 1 0.009 0.0326 0.0602
Brugia malayi cathepsin L-like precursor 0.0396 0.1587 0.2931
Plasmodium vivax dihydrolipoyl dehydrogenase, apicoplast, putative 0.0013 0.0009 0.0015
Brugia malayi Angiotensin-converting enzyme family protein 0.0603 0.2442 0.4511
Giardia lamblia Pyruvate kinase 0.0017 0.0028 0.0108
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.0203 0.0792 0.1463
Loa Loa (eye worm) matrixin family protein 0.0101 0.0373 0.0688
Loa Loa (eye worm) hypothetical protein 0.0136 0.0515 0.0951
Echinococcus granulosus allatostatin A receptor 0.0033 0.0092 0.017
Brugia malayi Cytochrome P450 family protein 0.0019 0.0035 0.0065
Trichomonas vaginalis conserved hypothetical protein 0.0033 0.0093 0.0417
Echinococcus multilocularis glutamate receptor, ionotrophic, AMPA 3 0.0074 0.0263 0.0263
Giardia lamblia Cathepsin L precursor 0.0136 0.0515 0.2516
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0033 0.0092 0.017
Trypanosoma cruzi cytochrome P450, putative 0.0019 0.0035 0.0054
Treponema pallidum hypothetical protein 0.0015 0.0018 0.0078
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD35 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0018 0.0028 0.0186
Brugia malayi cathepsin Z-like cysteine proteinase 0.0136 0.0515 0.0951
Echinococcus granulosus alpha 1A adrenergic receptor 0.0033 0.0092 0.017
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.0074 0.0263 0.0485
Onchocerca volvulus 0.0033 0.0092 0.0486
Echinococcus granulosus Chromo domain 0.0033 0.0093 0.0171
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0026 0.0061 0.026
Trichomonas vaginalis inositol monophosphatase, putative 0.0072 0.025 0.1197
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.0074 0.0263 0.0485
Mycobacterium ulcerans dihydrolipoamide dehydrogenase, LpdB 0.0013 0.0009 0.0026
Loa Loa (eye worm) hypothetical protein 0.0039 0.0118 0.0218
Entamoeba histolytica acyl-coA synthetase, putative 0.0025 0.0059 0.0239
Onchocerca volvulus 0.0033 0.0092 0.0486
Plasmodium falciparum heterochromatin protein 1 0.0033 0.0093 0.0468
Entamoeba histolytica endonuclease/exonuclease/phosphatase family protein 0.0015 0.0018 0.0017
Loa Loa (eye worm) hypothetical protein 0.0033 0.0092 0.017
Loa Loa (eye worm) hypothetical protein 0.0033 0.0093 0.0171
Brugia malayi intermediate filament protein 0.0026 0.0065 0.0119
Schistosoma mansoni cathepsin S (C01 family) 0.0136 0.0515 0.0951
Leishmania major 2-oxoglutarate dehydrogenase, e3 component, lipoamidedehydrogenase-like protein 0.0013 0.0009 0.0014
Trichomonas vaginalis penicillin-binding protein, putative 0.0039 0.0118 0.0542
Schistosoma mansoni glutamate receptor kainate 0.0026 0.0062 0.0115
Echinococcus multilocularis cpg binding protein 0.003 0.0078 0.0078
Loa Loa (eye worm) prolyl oligopeptidase 0.0014 0.0014 0.0027
Trichomonas vaginalis glucosylceramidase, putative 0.0176 0.0679 0.3319
Trichomonas vaginalis conserved hypothetical protein 0.0033 0.0093 0.0417
Brugia malayi Matrixin family protein 0.0046 0.0144 0.0265
Schistosoma mansoni prolyl oligopeptidase (S09 family) 0.0136 0.0516 0.0954
Giardia lamblia Cathepsin L precursor 0.0136 0.0515 0.2516
Plasmodium vivax vivapain-1 0.0203 0.0792 0.4232
Brugia malayi Protein cec-1. 0.0033 0.0093 0.0171
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0463 0.1864 0.9179
Loa Loa (eye worm) hypothetical protein 0.0033 0.0092 0.017
Schistosoma mansoni peptide (allatostatin/somatostatin)-like receptor 0.0033 0.0092 0.017
Leishmania major UDP-galactopyranose mutase 0.0014 0.0015 0.0046
Echinococcus granulosus GTP binding nuclear protein Ran 0.0023 0.0051 0.0095
Schistosoma mansoni glutamate receptor NMDA 0.0031 0.0083 0.0153
Loa Loa (eye worm) beta-lactamase 0.0039 0.0118 0.0218
Entamoeba histolytica inositol polyphosphate-5-phosphatase, putative 0.0015 0.0018 0.0017
Echinococcus multilocularis geminin 0.0678 0.2749 0.2749
Leishmania major cathepsin L-like protease 0.0463 0.1864 0.918
Brugia malayi Pyruvate kinase, muscle isozyme 0.0034 0.0096 0.0177
Brugia malayi AKH receptor 0.0033 0.0092 0.017
Leishmania major inositol phosphosphingolipid phospholipase C-Like 0.0015 0.0018 0.0058
Plasmodium vivax AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0074 0.0263 0.1382
Entamoeba histolytica cysteine protease, putative 0.0136 0.0515 0.2707
Plasmodium vivax serine-repeat antigen (SERA) 0.0136 0.0515 0.274
Brugia malayi Cathepsin L-like precursor 0.0463 0.1864 0.3443
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0136 0.0515 0.0951
Leishmania major cysteine peptidase C (CPC),CPC cysteine peptidase, Clan CA, family C1, Cathepsin B-like 0.0503 0.203 1
Giardia lamblia NADH oxidase lateral transfer candidate 0.0013 0.0009 0.0014
Toxoplasma gondii endonuclease/exonuclease/phosphatase family protein 0.0015 0.0018 0.0058
Trichomonas vaginalis glucosylceramidase, putative 0.0167 0.0642 0.3136
Mycobacterium tuberculosis Conserved hypothetical protein 0.0039 0.0117 0.1019
Loa Loa (eye worm) hypothetical protein 0.0033 0.0093 0.0171
Toxoplasma gondii LsmAD domain-containing protein 0.0106 0.039 0.19
Loa Loa (eye worm) angiotensin-converting enzyme family protein 0.0603 0.2442 0.4511
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0136 0.0515 0.2505
Loa Loa (eye worm) hypothetical protein 0.0033 0.0092 0.017
Loa Loa (eye worm) hypothetical protein 0.0149 0.0569 0.1051
Entamoeba histolytica chromodomain-helicase-DNA-binding protein, putative 0.0033 0.0093 0.0424
Echinococcus granulosus g protein coupled receptor 0.0033 0.0092 0.017
Onchocerca volvulus 0.0033 0.0092 0.0486
Loa Loa (eye worm) hypothetical protein 0.0015 0.0018 0.0032
Plasmodium vivax serine-repeat antigen (SERA) 0.0136 0.0515 0.274
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0463 0.1864 0.9179
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0039 0.0118 0.0218
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0231 0.0906 0.1674
Trichomonas vaginalis sphingomyelinase C 2 precursor, putative 0.0015 0.0018 0.0045
Echinococcus multilocularis cathepsin L 0.0203 0.0792 0.0792
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0292 0.116 0.5696
Giardia lamblia Cathepsin L-like protease 0.0136 0.0515 0.2516
Plasmodium vivax importin-beta 2, putative 0.0032 0.0086 0.043
Schistosoma mansoni hypothetical protein 0.0065 0.0222 0.041
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0033 0.0092 0.017
Mycobacterium tuberculosis Probable exported protein 0.0015 0.0018 0.0084
Brugia malayi G-protein coupled receptor 0.0033 0.0092 0.017
Trypanosoma cruzi cytochrome P450, putative 0.0019 0.0035 0.0054
Plasmodium falciparum serine repeat antigen 3 0.0136 0.0515 0.274
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0463 0.1864 0.9179
Echinococcus granulosus pyruvate kinase 0.0034 0.0096 0.0177
Toxoplasma gondii pyruvate dehydrogenase complex subunit PDH-E3II 0.0013 0.0009 0.0014
Echinococcus granulosus synaptojanin 1 0.0015 0.0018 0.0032
Loa Loa (eye worm) hypothetical protein 0.0025 0.0059 0.0108
Loa Loa (eye worm) hypothetical protein 0.0033 0.0092 0.017
Entamoeba histolytica hypothetical protein 0.0033 0.0093 0.0424
Trichomonas vaginalis importin beta-1, putative 0.0026 0.0061 0.026
Entamoeba histolytica cysteine protease, putative 0.0203 0.0792 0.4205
Schistosoma mansoni sex comb on midleg homolog 0.0048 0.0155 0.0287
Brugia malayi Kringle domain containing protein 0.0017 0.0026 0.0049
Echinococcus granulosus neuropeptides capa receptor 0.0033 0.0092 0.017
Toxoplasma gondii preprocathepsin c precursor, putative 0.0136 0.0515 0.2516
Onchocerca volvulus 0.0033 0.0092 0.0486
Loa Loa (eye worm) hypothetical protein 0.0033 0.0092 0.017
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0126 0.0474 0.0876
Loa Loa (eye worm) hypothetical protein 0.0033 0.0092 0.017
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0203 0.0792 0.3885
Entamoeba histolytica chromodomain-helicase-DNA-binding protein, putative 0.0033 0.0093 0.0424
Leishmania major dipeptidyl-peptidase 8-like serine peptidase, putative,serine peptidase, Clan SC, Family S9B 0.0014 0.0014 0.0043
Onchocerca volvulus 0.0033 0.0092 0.0486
Loa Loa (eye worm) helicase 0.0033 0.0093 0.0171
Trichomonas vaginalis ran, putative 0.0023 0.0051 0.0212
Loa Loa (eye worm) hypothetical protein 0.0033 0.0092 0.017
Entamoeba histolytica cysteine proteinase, putative 0.0203 0.0792 0.4205
Loa Loa (eye worm) hypothetical protein 0.0033 0.0092 0.017
Brugia malayi GnHR receptor homolog 0.0033 0.0092 0.017
Echinococcus granulosus hypothetical protein 0.0033 0.0092 0.017
Mycobacterium leprae Probable fructose bisphosphate aldolase Fba 0.0143 0.0544 1
Loa Loa (eye worm) GTP-binding nuclear protein RAN/TC4 0.0023 0.0051 0.0095
Trichomonas vaginalis D-aminoacylase, putative 0.0039 0.0118 0.0542
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0463 0.1864 0.9179
Toxoplasma gondii aldehyde dehydrogenase 0.0178 0.069 0.338
Loa Loa (eye worm) pyruvate kinase 0.0034 0.0096 0.0177
Echinococcus multilocularis dihydrolipoamide dehydrogenase 0.0013 0.0009 0.0009
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0033 0.0092 0.017
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0463 0.1864 0.9179
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0013 0.0009 0.0014
Loa Loa (eye worm) hypothetical protein 0.0032 0.0089 0.0164
Loa Loa (eye worm) G-protein coupled receptor 0.0033 0.0092 0.017
Echinococcus granulosus thioredoxin glutathione reductase 0.0038 0.011 0.0204
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0136 0.0515 0.2505
Brugia malayi Endonuclease/Exonuclease/phosphatase family protein 0.0015 0.0018 0.0032
Schistosoma mansoni hypothetical protein 0.0047 0.0151 0.0278
Echinococcus multilocularis glutamate receptor subunit protein glur 0.0053 0.0175 0.0175
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0463 0.1864 0.9179
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0463 0.1864 0.9179
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0231 0.0906 0.1674
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0136 0.0515 0.0951
Loa Loa (eye worm) hypothetical protein 0.0033 0.0092 0.017
Loa Loa (eye worm) hypothetical protein 0.0014 0.0014 0.0027
Schistosoma mansoni amine GPCR 0.0033 0.0092 0.017
Brugia malayi Melatonin receptor type 1A 0.0033 0.0092 0.017
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.0039 0.0118 0.1027
Brugia malayi Matrix metalloprotease, N-terminal domain containing protein 0.0056 0.0185 0.0341
Giardia lamblia Cathepsin B precursor 0.0136 0.0515 0.2516
Giardia lamblia Cathepsin B precursor 0.0503 0.203 1
Echinococcus granulosus cathepsin L 0.0136 0.0515 0.0951
Echinococcus multilocularis GPCR, family 2 0.0126 0.0474 0.0474
Giardia lamblia Pyruvate kinase 0.0034 0.0096 0.0445
Mycobacterium tuberculosis Conserved protein 0.0039 0.0118 0.1027
Echinococcus granulosus thyrotropin releasing hormone receptor 0.0033 0.0092 0.017
Giardia lamblia Encystation-specific protease 0.0136 0.0515 0.2516
Echinococcus multilocularis neuropeptide receptor A26 0.0033 0.0092 0.0092
Echinococcus granulosus polycomb protein SCMH1 0.0048 0.0155 0.0287
Echinococcus granulosus suppression of tumorigenicity 18 protein 0.0055 0.0183 0.0338
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0463 0.1864 0.9179
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0136 0.0515 0.2505
Trichomonas vaginalis conserved hypothetical protein 0.0033 0.0093 0.0417
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0033 0.0092 0.017
Mycobacterium ulcerans dihydrolipoamide dehydrogenase 0.0013 0.0009 0.0026
Echinococcus multilocularis rhodopsin orphan GPCR 0.0033 0.0092 0.0092
Echinococcus granulosus dihydrolipoamide dehydrogenase 0.0013 0.0009 0.0016
Echinococcus granulosus potassium voltage gated channel subfamily H 0.0037 0.0109 0.0201
Brugia malayi Matrixin family protein 0.0046 0.0144 0.0265
Toxoplasma gondii pyruvate kinase PyKII 0.0017 0.0028 0.0108
Trypanosoma cruzi mitochondrial protein 99, putative 0.0015 0.0018 0.0022
Echinococcus granulosus SAM and MBT domain containing protein 0.0048 0.0155 0.0287
Schistosoma mansoni amine oxidase 0.0014 0.0015 0.0028
Mycobacterium ulcerans protoporphyrinogen oxidase 0.0014 0.0015 0.0088
Onchocerca volvulus 0.0136 0.0515 0.2758
Trichomonas vaginalis ap endonuclease, putative 0.0074 0.0263 0.1257
Brugia malayi Dopamine receptor 0.0033 0.0092 0.017
Trichomonas vaginalis conserved hypothetical protein 0.0136 0.0515 0.2505
Schistosoma mansoni biogenic amine receptor 0.0033 0.0092 0.017
Mycobacterium ulcerans exodeoxyribonuclease III protein XthA 0.0074 0.0263 0.2401
Onchocerca volvulus Deterin homolog 0.0053 0.0172 0.0917
Entamoeba histolytica hypothetical protein 0.0033 0.0093 0.0424
Entamoeba histolytica acyl-CoA synthetase, putative 0.0025 0.0059 0.0239
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD2 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0025 0.0059 0.0823
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0026 0.0061 0.026
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0013 0.0009 0.0014
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0398 0.1595 0.2947
Loa Loa (eye worm) hypothetical protein 0.0067 0.0233 0.043
Loa Loa (eye worm) hypothetical protein 0.0033 0.0092 0.017
Plasmodium falciparum dipeptidyl aminopeptidase 1 0.0136 0.0515 0.274
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0463 0.1864 0.9179
Echinococcus granulosus Dipeptidyl peptidase 9 0.0014 0.0014 0.0027
Trypanosoma cruzi trypanothione reductase, putative 0.0013 0.0009 0.0005
Echinococcus granulosus sex peptide receptor 0.0033 0.0092 0.017
Echinococcus granulosus rhodopsin orphan GPCR 0.0033 0.0092 0.017
Plasmodium falciparum DNase I-like protein, putative 0.0015 0.0018 0.0063
Trypanosoma cruzi hypothetical protein, conserved 0.0039 0.0118 0.0208
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0463 0.1864 0.9179
Brugia malayi larval opioid receptor 0.0033 0.0092 0.017
Toxoplasma gondii thioredoxin reductase 0.0037 0.0108 0.0507
Mycobacterium ulcerans acyl-CoA synthetase 0.0025 0.0059 0.0495
Entamoeba histolytica hypothetical protein 0.0136 0.0515 0.2707
Trypanosoma brucei DNA polymerase kappa, putative 0.0039 0.0117 0.0551
Toxoplasma gondii kringle domain-containing protein 0.0017 0.0026 0.0101
Loa Loa (eye worm) hypothetical protein 0.0015 0.0018 0.0032
Onchocerca volvulus Neuropeptide F receptor homolog 0.0033 0.0092 0.0486
Plasmodium falciparum exodeoxyribonuclease III, putative 0.0015 0.0018 0.0063
Loa Loa (eye worm) glutathione reductase 0.0037 0.0108 0.02
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD3 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0018 0.0028 0.0186
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0463 0.1864 0.918
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.1324 0.5413 1
Onchocerca volvulus 0.0026 0.0065 0.034
Plasmodium falciparum chromodomain-helicase-DNA-binding protein 1 homolog, putative 0.0033 0.0093 0.0468
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0033 0.0092 0.017
Echinococcus multilocularis muscleblind protein 0.0149 0.0569 0.0569
Loa Loa (eye worm) endonuclease/Exonuclease/phosphatase 0.0015 0.0018 0.0032
Loa Loa (eye worm) hypothetical protein 0.0033 0.0092 0.017
Loa Loa (eye worm) hypothetical protein 0.0033 0.0093 0.0171
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0231 0.0906 0.0906
Onchocerca volvulus 0.0033 0.0092 0.0486
Schistosoma mansoni hypothetical protein 0.0017 0.0026 0.0049
Echinococcus multilocularis growth hormone secretagogue receptor type 1 0.0033 0.0092 0.0092
Schistosoma mansoni chromobox protein 0.0033 0.0093 0.0171
Brugia malayi Cathepsin L-like cysteine proteinase 0.0396 0.1587 0.2931
Trichomonas vaginalis conserved hypothetical protein 0.0033 0.0093 0.0417
Echinococcus multilocularis terminal deoxycytidyl transferase rev1 0.0039 0.0117 0.0117
Echinococcus multilocularis glutamate receptor 2 0.0074 0.0263 0.0263
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0231 0.0906 0.1674
Loa Loa (eye worm) hypothetical protein 0.0055 0.0183 0.0338
Plasmodium vivax cysteine repeat modular protein 1, putative 0.0017 0.0026 0.0111
Plasmodium vivax ataxin-2 like protein, putative 0.0106 0.039 0.207
Entamoeba histolytica endonuclease/exonuclease/phosphatase domain containing protein 0.0015 0.0018 0.0017
Trichomonas vaginalis ap endonuclease, putative 0.0074 0.0263 0.1257
Onchocerca volvulus 0.0034 0.0095 0.0505
Trichomonas vaginalis conserved hypothetical protein 0.0033 0.0093 0.0417
Plasmodium falciparum carbon catabolite repressor protein 4, putative 0.0015 0.0018 0.0063
Entamoeba histolytica endonuclease/exonuclease/phosphatase family protein 0.0015 0.0018 0.0017
Brugia malayi ImpB/MucB/SamB family protein 0.0039 0.0117 0.0217
Leishmania major cysteine peptidase A (CPA) 0.0463 0.1864 0.918
Trypanosoma brucei PAB1-binding protein , putative 0.0106 0.039 0.19
Brugia malayi Serotonin receptor 0.0033 0.0092 0.017
Trypanosoma brucei pyruvate kinase 1 0.0034 0.0096 0.0445
Echinococcus multilocularis cathepsin b 0.1324 0.5413 0.5413
Trichomonas vaginalis chromobox protein, putative 0.0033 0.0093 0.0417
Plasmodium falciparum AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0074 0.0263 0.1382
Loa Loa (eye worm) hypothetical protein 0.0013 0.0008 0.0015
Loa Loa (eye worm) hypothetical protein 0.0253 0.0997 0.1843
Trypanosoma brucei dihydrolipoamide dehydrogenase, point mutation 0.0013 0.0009 0.0014
Brugia malayi Endonuclease/Exonuclease/phosphatase family protein 0.0015 0.0018 0.0032
Echinococcus multilocularis pyruvate kinase 0.0017 0.0028 0.0028
Schistosoma mansoni dihydrolipoamide dehydrogenase 0.0013 0.0009 0.0016
Entamoeba histolytica cysteine protease, putative 0.0203 0.0792 0.4205
Loa Loa (eye worm) hypothetical protein 0.0025 0.0059 0.0108
Echinococcus granulosus rhodopsin orphan GPCR 0.0033 0.0092 0.017
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.0023 0.0051 0.0084
Leishmania major 4-coumarate:coa ligase-like protein 0.0025 0.0059 0.0261
Schistosoma mansoni biogenic amine receptor 0.0033 0.0092 0.017
Echinococcus multilocularis 0.0014 0.0015 0.0015
Brugia malayi CHD4 protein 0.0035 0.0099 0.0184
Brugia malayi cathepsin L precursor 0.0136 0.0515 0.0951
Brugia malayi cathepsin B-like cysteine proteinase 0.1324 0.5413 1
Loa Loa (eye worm) hypothetical protein 0.0033 0.0092 0.017
Echinococcus granulosus intermediate filament protein 0.0026 0.0065 0.0119
Entamoeba histolytica exodeoxyribonuclease III, putative 0.0074 0.0263 0.1342
Trypanosoma cruzi PAB1-binding protein , putative 0.0106 0.039 0.0711
Trypanosoma cruzi cruzipain precursor, putative 0.0067 0.0233 0.042
Loa Loa (eye worm) hypothetical protein 0.0033 0.0092 0.017
Toxoplasma gondii dipeptidyl peptidase iv (dpp iv) n-terminal region domain-containing protein 0.0014 0.0014 0.0043
Brugia malayi Calcitonin receptor-like protein seb-1 0.0398 0.1595 0.2947
Mycobacterium tuberculosis Probable oxidoreductase 0.0094 0.0343 0.3136
Echinococcus multilocularis Glutamate receptor, ionotropic kainate 2 0.0031 0.0083 0.0083
Schistosoma mansoni chromobox protein 0.0571 0.2307 0.4262
Loa Loa (eye worm) hypothetical protein 0.0033 0.0092 0.017
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0463 0.1864 0.918
Echinococcus granulosus GPCR family 2 0.0126 0.0474 0.0876
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0033 0.0092 0.0092
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.0023 0.0051 0.0084
Echinococcus granulosus cathepsin b 0.1324 0.5413 1
Trichomonas vaginalis Clan CA, family C1, cathepsin L or H-like cysteine peptidase 0.0136 0.0515 0.2505
Trypanosoma cruzi cysteine proteinase, putative 0.0203 0.0792 0.1454
Trypanosoma cruzi cysteine peptidase (N-terminal), putative 0.0203 0.0792 0.1454
Onchocerca volvulus 0.0463 0.1864 1
Entamoeba histolytica myo-inositol monophosphatase, putative 0.0072 0.025 0.1276
Onchocerca volvulus 0.0017 0.0026 0.0134
Echinococcus multilocularis inositol monophosphatase 1 0.0072 0.025 0.025
Schistosoma mansoni DNA polymerase IV / kappa 0.0012 0.0006 0.0011
Loa Loa (eye worm) neuropeptide F receptor 0.0033 0.0092 0.017
Brugia malayi cahepsin L-like non-peptiedase homolog 0.0136 0.0515 0.0951
Toxoplasma gondii histone lysine methyltransferase SET1 0.0053 0.0175 0.0838
Onchocerca volvulus 0.0033 0.0092 0.0486
Plasmodium vivax serine-repeat antigen 4 (SERA) 0.0136 0.0515 0.274
Loa Loa (eye worm) hypothetical protein 0.0071 0.0249 0.046
Mycobacterium tuberculosis Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB 0.0085 0.0304 0.2772
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0463 0.1864 0.918
Loa Loa (eye worm) hypothetical protein 0.0033 0.0092 0.017
Plasmodium vivax heterochromatin protein 1, putative 0.0033 0.0093 0.0468
Mycobacterium ulcerans extragenic suppressor protein SuhB 0.0072 0.025 0.2288
Onchocerca volvulus 0.0052 0.0171 0.0909
Entamoeba histolytica hypothetical protein 0.0026 0.0061 0.0253
Plasmodium falciparum serine repeat antigen 5 0.0136 0.0515 0.274
Plasmodium falciparum conserved Plasmodium protein, unknown function 0.0033 0.0093 0.0468
Mycobacterium tuberculosis Fatty-acid-AMP ligase FadD30 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) 0.0019 0.0033 0.0226
Echinococcus granulosus cysteine protease 0.0203 0.0792 0.1463
Echinococcus granulosus pyruvate kinase 0.0034 0.0096 0.0177
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0037 0.0107 0.0487
Giardia lamblia Cathepsin B-like cysteine proteinase 3 precursor 0.0136 0.0515 0.2516
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.0039 0.0118 0.105
Echinococcus granulosus Glutamate receptor ionotropic kainate 2 0.0031 0.0083 0.0153
Echinococcus multilocularis tissue type plasminogen activator 0.0017 0.0026 0.0026
Trypanosoma cruzi Endonuclease/Exonuclease/phosphatase family, putative 0.0015 0.0018 0.0022
Trypanosoma cruzi DNA polymerase kappa, putative 0.0039 0.0117 0.0206
Brugia malayi Voltage-gated potassium channel, HERG (KCNH2)-related. C. elegans unc-103 ortholog 0.0037 0.0109 0.0201
Mycobacterium ulcerans long-chain-fatty-acid--CoA ligase 0.0025 0.0059 0.0495
Trypanosoma cruzi cysteine peptidase, putative 0.0067 0.0233 0.042
Leishmania major DNA polymerase kappa, putative,DNA polymerase IV, putative 0.0039 0.0117 0.0551
Loa Loa (eye worm) hypothetical protein 0.0039 0.0118 0.0218
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0033 0.0092 0.0092
Brugia malayi Glutamate receptor 1 precursor 0.007 0.0242 0.0448
Echinococcus granulosus neutral sphingomyelinase 0.0015 0.0018 0.0032
Loa Loa (eye worm) G-protein coupled receptor 0.0033 0.0092 0.017
Mycobacterium tuberculosis Conserved hypothetical protein 0.0014 0.0015 0.0062
Mycobacterium tuberculosis NAD(P)H quinone reductase LpdA 0.0094 0.0343 0.3136
Onchocerca volvulus Cathepsin L homolog 0.0463 0.1864 1
Loa Loa (eye worm) pyruvate kinase 0.0034 0.0096 0.0177
Schistosoma mansoni voltage-gated potassium channel 0.0041 0.0123 0.0227
Leishmania major aldehyde dehydrogenase, mitochondrial precursor 0.0178 0.069 0.338
Leishmania major 4-coumarate:coa ligase-like protein 0.0025 0.0059 0.0261
Trichomonas vaginalis D-aminoacylase, putative 0.0039 0.0118 0.0542
Plasmodium falciparum pyruvate kinase 0.0034 0.0096 0.0485
Onchocerca volvulus 0.0033 0.0092 0.0486
Trichomonas vaginalis penicillin-binding protein, putative 0.0039 0.0118 0.0542
Schistosoma mansoni prolyl oligopeptidase (S09 family) 0.0136 0.0516 0.0954
Loa Loa (eye worm) POT family protein 0.004 0.0118 0.0219
Brugia malayi prolyl oligopeptidase family protein 0.0014 0.0014 0.0027
Plasmodium vivax serine-repeat antigen 4 (SERA), putative 0.0136 0.0515 0.274
Onchocerca volvulus 0.0463 0.1864 1
Leishmania major cathepsin L-like protease 0.0463 0.1864 0.918
Echinococcus multilocularis somatostatin receptor 0.0033 0.0092 0.0092
Trichomonas vaginalis Clan CA, family C1, cathepsin H-like cysteine peptidase 0.0136 0.0515 0.2505
Loa Loa (eye worm) hypothetical protein 0.0014 0.0015 0.0028
Trypanosoma cruzi pyruvate kinase 2, putative 0.0034 0.0096 0.0167
Trypanosoma cruzi prolyl endopeptidase 0.0136 0.0516 0.0944
Trypanosoma cruzi trypanothione reductase, putative 0.0037 0.0108 0.019
Loa Loa (eye worm) hypothetical protein 0.0033 0.0092 0.017
Mycobacterium tuberculosis Probable pyruvate kinase PykA 0.0034 0.0096 0.0819
Plasmodium vivax pyruvate kinase 2, putative 0.0017 0.0028 0.0118
Schistosoma mansoni hypothetical protein 0.0126 0.0474 0.0876
Loa Loa (eye worm) hypothetical protein 0.0136 0.0515 0.0951
Trichomonas vaginalis glucosylceramidase, putative 0.0176 0.0679 0.3319
Mycobacterium tuberculosis Probable lipase LipD 0.0039 0.0118 0.1027
Echinococcus granulosus growth hormone secretagogue receptor type 1 0.0033 0.0092 0.017
Leishmania major hypothetical protein, conserved 0.0106 0.039 0.19
Loa Loa (eye worm) hypothetical protein 0.0033 0.0092 0.017
Entamoeba histolytica cysteine protease, putative 0.0136 0.0515 0.2707
Plasmodium vivax unspecified product 0.0203 0.0792 0.4232
Trypanosoma cruzi endonuclease/exonuclease/phosphatase, putative 0.0015 0.0018 0.0022
Toxoplasma gondii prolyl endopeptidase 0.0136 0.0516 0.2522
Plasmodium falciparum dipeptidyl aminopeptidase 2 0.0136 0.0515 0.274
Schistosoma mansoni chromodomain helicase DNA binding protein 0.0035 0.0099 0.0184
Leishmania major GTP-binding protein, putative 0.0023 0.0051 0.0225
Schistosoma mansoni inositol monophosphatase 0.0072 0.025 0.0463
Plasmodium falciparum serine repeat antigen 9 0.0136 0.0515 0.274
Loa Loa (eye worm) hypothetical protein 0.002 0.004 0.0074
Echinococcus multilocularis rhodopsin orphan GPCR 0.0033 0.0092 0.0092
Brugia malayi cathepsin L-like cysteine proteinase, identical 0.0067 0.0233 0.043
Trypanosoma cruzi hypothetical protein, conserved 0.0039 0.0118 0.0208
Schistosoma mansoni scm-relatedprotein containing 4 mbt domains (sfmbt) 0.0048 0.0155 0.0287
Echinococcus multilocularis G protein coupled receptor 139 0.0033 0.0092 0.0092
Loa Loa (eye worm) hypothetical protein 0.0025 0.0059 0.0108
Giardia lamblia Dipeptidyl-peptidase I precursor 0.0136 0.0515 0.2516
Schistosoma mansoni subfamily C1A non-peptidase homologue (C01 family) 0.0136 0.0515 0.0951
Echinococcus granulosus cathepsin L cysteine protease 0.0203 0.0792 0.1463
Loa Loa (eye worm) hypothetical protein 0.0033 0.0092 0.017
Plasmodium vivax lysine-specific histone demethylase 1, putative 0.0014 0.0015 0.0051
Echinococcus multilocularis neuropeptides capa receptor 0.0033 0.0092 0.0092
Echinococcus multilocularis muscleblind protein 1 0.0149 0.0569 0.0569
Mycobacterium tuberculosis Possible penicillin-binding protein 0.0252 0.0994 0.9236
Schistosoma mansoni hypothetical protein 0.0678 0.2749 0.5078
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0033 0.0092 0.017
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0463 0.1864 0.9179
Brugia malayi Cathepsin L-like precursor 0.0396 0.1587 0.2931
Trypanosoma cruzi oligopeptidase b 0.0054 0.0179 0.0319
Leishmania major inositol/phosphatidylinositol phosphatase, putative 0.0015 0.0018 0.0058
Toxoplasma gondii histone lysine-specific demethylase LSD1/BHC110/KDMA1A 0.0016 0.0022 0.0081
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.0026 0.0065 0.0119
Mycobacterium leprae Probable lipase LipE 0.0039 0.0118 0.1947
Plasmodium falciparum glutathione reductase 0.0037 0.0108 0.0553
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.0463 0.1864 0.9179
Schistosoma mansoni hypothetical protein 0.0272 0.1077 0.1989
Schistosoma mansoni ap endonuclease 0.0074 0.0263 0.0485
Schistosoma mansoni subfamily S9B unassigned peptidase (S09 family) 0.0014 0.0014 0.0027
Trypanosoma brucei Endonuclease/Exonuclease/phosphatase family, putative 0.0015 0.0018 0.0058
Trichomonas vaginalis conserved hypothetical protein 0.0014 0.0014 0.0029
Trypanosoma cruzi hypothetical protein, conserved 0.0014 0.0014 0.0016
Loa Loa (eye worm) matrix metalloproteinase 0.0046 0.0144 0.0265
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.0074 0.0263 0.0263
Loa Loa (eye worm) CXXC zinc finger family protein 0.0028 0.0072 0.0132
Echinococcus multilocularis biogenic amine (5HT) receptor 0.0033 0.0092 0.0092
Echinococcus multilocularis deoxyribonuclease 1 2 0.0015 0.0018 0.0018
Echinococcus granulosus neuropeptide s receptor 0.0033 0.0092 0.017
Echinococcus multilocularis SAM and MBT domain containing protein 0.0048 0.0155 0.0155
Brugia malayi Dopamine receptor protein 2 0.0033 0.0092 0.017
Trypanosoma cruzi major cysteine proteinase, putative 0.0136 0.0515 0.0942
Schistosoma mansoni rab geranylgeranyl transferase alpha subunit 0.0039 0.0117 0.0217
Loa Loa (eye worm) hypothetical protein 0.0033 0.0092 0.017
Toxoplasma gondii NADPH-glutathione reductase 0.0013 0.0009 0.0014
Leishmania major DNA polymerase eta, putative 0.0039 0.0117 0.0551
Trichomonas vaginalis Phospholipase C precursor, putative 0.0015 0.0018 0.0045
Echinococcus granulosus serotonin receptor 0.0033 0.0092 0.017
Loa Loa (eye worm) hypothetical protein 0.0126 0.0474 0.0876
Brugia malayi prolyl oligopeptidase family protein 0.0014 0.0014 0.0027
Onchocerca volvulus 0.0046 0.0144 0.0764
Mycobacterium ulcerans protease II (oligopeptidase B), PtrB 0.0054 0.0179 0.1615
Entamoeba histolytica cysteine protease, putative 0.0203 0.0792 0.4205
Brugia malayi G-protein coupled receptor 0.0033 0.0092 0.017
Echinococcus multilocularis neuropeptide Y receptor 0.0033 0.0092 0.0092
Echinococcus multilocularis thioredoxin glutathione reductase 0.0038 0.011 0.011
Loa Loa (eye worm) hypothetical protein 0.0012 0.0006 0.0011
Brugia malayi hypothetical protein 0.0033 0.0092 0.017
Mycobacterium tuberculosis Probable peptidoglycan hydrolase 0.0056 0.0185 0.165
Mycobacterium ulcerans aldehyde dehydrogenase 0.0178 0.069 0.6396
Loa Loa (eye worm) hypothetical protein 0.0026 0.0065 0.0119
Echinococcus multilocularis pyruvate kinase 0.0034 0.0096 0.0096
Onchocerca volvulus 0.0463 0.1864 1
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0398 0.1595 0.2947
Trichomonas vaginalis conserved hypothetical protein 0.0136 0.0515 0.2505
Echinococcus granulosus G protein coupled receptor 139 0.0033 0.0092 0.017
Loa Loa (eye worm) intermediate filament protein 0.0026 0.0065 0.0119
Entamoeba histolytica cysteine protease, putative 0.0136 0.0515 0.2707
Schistosoma mansoni hypothetical protein 0.0126 0.0474 0.0876
Mycobacterium ulcerans aldehyde dehydrogenase 0.0178 0.069 0.6396
Onchocerca volvulus 0.0033 0.0092 0.0486
Loa Loa (eye worm) hypothetical protein 0.0033 0.0092 0.017
Plasmodium vivax hypothetical protein, conserved 0.0014 0.0014 0.0046
Echinococcus granulosus cathepsin l1 0.0463 0.1864 0.3443
Mycobacterium tuberculosis Probable esterase LipL 0.0039 0.0118 0.1027
Echinococcus granulosus pyruvate kinase 0.0017 0.0028 0.0051
Toxoplasma gondii 'chromo' (CHRromatin Organization MOdifier) domain-containing protein 0.0033 0.0093 0.043
Trichomonas vaginalis glucosylceramidase, putative 0.0167 0.0642 0.3136
Echinococcus granulosus lamin 0.0026 0.0065 0.0119
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0013 0.0009 0.0005
Loa Loa (eye worm) hypothetical protein 0.0046 0.0144 0.0265
Trypanosoma brucei DNA polymerase kappa, putative 0.0027 0.0067 0.0303
Schistosoma mansoni amine oxidase 0.0014 0.0015 0.0028
Brugia malayi cathepsin L-like cysteine proteinase 0.0136 0.0515 0.0951
Echinococcus granulosus rhodopsin orphan GPCR 0.0033 0.0092 0.017
Echinococcus multilocularis cysteine protease 0.0463 0.1864 0.1864
Loa Loa (eye worm) hypothetical protein 0.0033 0.0092 0.017
Loa Loa (eye worm) hypothetical protein 0.0463 0.1864 0.3443
Onchocerca volvulus Heterochromatin protein 1 homolog 0.0033 0.0093 0.0491
Brugia malayi Cathepsin L-like precursor 0.0463 0.1864 0.3443
Onchocerca volvulus Glucosylceramidase homolog 0.0167 0.0642 0.3442
Loa Loa (eye worm) inositol-1 0.0072 0.025 0.0463
Trypanosoma brucei DNA polymerase kappa, putative 0.0027 0.0067 0.0303
Echinococcus multilocularis neuropeptide s receptor 0.0033 0.0092 0.0092
Plasmodium falciparum ataxin-2 like protein, putative 0.0106 0.039 0.207
Trichomonas vaginalis glucosylceramidase, putative 0.0254 0.1002 0.4917
Trypanosoma cruzi inositol 5-phosphatase 1, putative 0.0015 0.0018 0.0022
Mycobacterium leprae PROBABLE PROTEASE II PTRBB (OLIGOPEPTIDASE B) 0.0054 0.0179 0.3089
Echinococcus granulosus glutamate receptor ionotrophic AMPA 3 0.0074 0.0263 0.0485
Toxoplasma gondii endonuclease/exonuclease/phosphatase family protein 0.0015 0.0018 0.0058
Giardia lamblia Cysteine protease 0.0136 0.0515 0.2516
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.1324 0.5413 1
Brugia malayi SET domain containing protein 0.0034 0.0095 0.0176
Schistosoma mansoni opsin-like receptor 0.0033 0.0092 0.017
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0231 0.0906 0.1674
Plasmodium falciparum serine repeat antigen 8 0.0136 0.0515 0.274
Mycobacterium ulcerans beta-lactamase 0.0039 0.0118 0.105
Loa Loa (eye worm) voltage and ligand gated potassium channel 0.0037 0.0109 0.0201
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0463 0.1864 0.918
Trichomonas vaginalis Clan SC, family S33, methylesterase-like serine peptidase 0.0014 0.0014 0.0029
Echinococcus multilocularis lamin dm0 0.0026 0.0065 0.0065
Echinococcus granulosus pyroglutamylated rfamide peptide receptor 0.0033 0.0092 0.017
Entamoeba histolytica Ran family GTPase 0.0023 0.0051 0.02
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0463 0.1864 0.3443
Brugia malayi amine oxidase, flavin-containing family protein 0.002 0.004 0.0074
Trichomonas vaginalis glucosylceramidase, putative 0.0167 0.0642 0.3136
Plasmodium falciparum GTP-binding nuclear protein RAN/TC4 0.0023 0.0051 0.0245
Echinococcus granulosus g protein coupled receptor 0.0033 0.0092 0.017
Trichomonas vaginalis DNA polymerase IV / kappa, putative 0.0039 0.0117 0.0538
Plasmodium falciparum cysteine proteinase falcipain 1 0.0203 0.0792 0.4232
Plasmodium vivax serine-repeat antigen (SERA), putative 0.0136 0.0515 0.274
Echinococcus multilocularis neuropeptide Y receptor 0.0033 0.0092 0.0092
Plasmodium vivax endonuclease/exonuclease/phosphatase domain containing protein 0.0015 0.0018 0.0063
Trichomonas vaginalis glucosylceramidase, putative 0.0254 0.1002 0.4917
Mycobacterium tuberculosis Probable protease II PtrBb [second part] (oligopeptidase B) 0.0054 0.0179 0.1593
Echinococcus granulosus cathepsin L 0.0203 0.0792 0.1463
Loa Loa (eye worm) CHromoDomain protein family member 0.0035 0.0099 0.0184
Schistosoma mansoni neuropeptide F-like receptor 0.0033 0.0092 0.017
Loa Loa (eye worm) fibroinase 0.0463 0.1864 0.3443
Echinococcus multilocularis g protein coupled receptor 0.0033 0.0092 0.0092
Trypanosoma brucei cysteine peptidase C (CPC) 0.0503 0.203 1
Loa Loa (eye worm) hypothetical protein 0.0014 0.0014 0.0027
Onchocerca volvulus 0.0048 0.0155 0.0826
Loa Loa (eye worm) hypothetical protein 0.0044 0.0136 0.025
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0033 0.0092 0.017
Brugia malayi latrophilin 2 splice variant baaae 0.0272 0.1077 0.1989
Loa Loa (eye worm) hypothetical protein 0.0012 0.0006 0.0011
Loa Loa (eye worm) hypothetical protein 0.0106 0.039 0.0721
Onchocerca volvulus Cathepsin L homolog 0.0463 0.1864 1
Giardia lamblia Cathepsin L-like protease 0.0136 0.0515 0.2516
Leishmania major cathepsin L-like protease 0.0463 0.1864 0.918
Onchocerca volvulus 0.0463 0.1864 1
Brugia malayi beta-lactamase family protein 0.0039 0.0118 0.0218
Schistosoma mansoni cathepsin C 0.0136 0.0515 0.0951
Trypanosoma brucei DNA polymerase kappa, putative 0.0039 0.0117 0.0551
Trypanosoma cruzi Endonuclease/Exonuclease/phosphatase family, putative 0.0015 0.0018 0.0022
Brugia malayi Intermediate filament tail domain containing protein 0.0026 0.0065 0.0119
Plasmodium vivax dihydrolipoyl dehydrogenase, mitochondrial, putative 0.0013 0.0009 0.0015
Echinococcus granulosus acylamino acid releasing enzyme 0.0014 0.0014 0.0027
Entamoeba histolytica cysteine proteinase 2 0.0203 0.0792 0.4205
Loa Loa (eye worm) hypothetical protein 0.0039 0.0117 0.0217
Echinococcus granulosus chromobox protein 1 0.0033 0.0093 0.0171
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0013 0.0009 0.0005
Giardia lamblia Cathepsin L precursor 0.0136 0.0515 0.2516
Schistosoma mansoni cript-related 0.0015 0.0018 0.0032
Onchocerca volvulus Pyruvate kinase homolog 0.0034 0.0096 0.0508
Onchocerca volvulus Pyruvate kinase homolog 0.0034 0.0096 0.0508
Brugia malayi Matrixin family protein 0.0046 0.0144 0.0265
Loa Loa (eye worm) neuropeptide F receptor 0.0033 0.0092 0.017
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0463 0.1864 0.9179
Brugia malayi hypothetical protein 0.0033 0.0093 0.0171
Plasmodium falciparum peptidase, putative 0.0014 0.0014 0.0046
Brugia malayi Muscleblind-like protein 0.0149 0.0569 0.1051
Echinococcus granulosus lysine specific histone demethylase 1A 0.0014 0.0015 0.0028
Echinococcus multilocularis glutamate receptor 2 0.0065 0.0223 0.0223
Echinococcus multilocularis rhodopsin orphan GPCR 0.0033 0.0092 0.0092
Trypanosoma cruzi cysteine peptidase, putative 0.0463 0.1864 0.3436
Loa Loa (eye worm) endonuclease/Exonuclease/phosphatase 0.0015 0.0018 0.0032
Entamoeba histolytica cysteine proteinase, putative 0.0463 0.1864 1
Brugia malayi Papain family cysteine protease containing protein 0.0136 0.0515 0.0951
Entamoeba histolytica cysteine proteinase, putative 0.0203 0.0792 0.4205
Echinococcus granulosus glutamate NMDA receptor subunit 0.0026 0.0062 0.0115
Echinococcus multilocularis fmrfamide receptor 0.0033 0.0092 0.0092
Trypanosoma brucei Alpha/beta hydrolase domain-containing protein 0.0014 0.0014 0.0043
Loa Loa (eye worm) Papain cysteine protease/cathepsin propeptide inhibitor-containing protein 0.0463 0.1864 0.3443
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0463 0.1864 0.9179
Leishmania major oligopeptidase b 0.0054 0.0179 0.0853
Trypanosoma cruzi serine peptidase, clan SC, family S9A-like protein, putative 0.0054 0.0179 0.0319
Trichomonas vaginalis type II inositol 5-phosphatase, putative 0.0015 0.0018 0.0045
Toxoplasma gondii hypothetical protein 0.0014 0.0014 0.0043
Entamoeba histolytica papain family cysteine protease domain containing protein 0.0136 0.0515 0.2707
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0136 0.0515 0.2505
Brugia malayi neuropeptide F receptor 0.0033 0.0092 0.017
Toxoplasma gondii endonuclease/exonuclease/phosphatase family protein 0.0015 0.0018 0.0058
Plasmodium vivax vivapain-2 0.0463 0.1864 1
Brugia malayi hypothetical protein 0.0033 0.0092 0.017
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0463 0.1864 0.9179
Echinococcus multilocularis matrix metallopeptidase 7 (M10 family) 0.0166 0.0639 0.0639
Leishmania major cathepsin L-like protease 0.0463 0.1864 0.918
Echinococcus multilocularis inositol polyphosphate 5 phosphatase OCRL 1 0.0015 0.0018 0.0018
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0013 0.0009 0.0005
Schistosoma mansoni glutamate receptor kainate 0.0026 0.0062 0.0115
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.0039 0.0118 0.1027
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0039 0.0118 0.0218
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.004 0.0119 0.0547
Loa Loa (eye worm) hypothetical protein 0.0039 0.0118 0.0218
Schistosoma mansoni histamine h1 receptor 0.0033 0.0092 0.017
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0396 0.1587 0.7808
Entamoeba histolytica endonuclease/exonuclease/phosphatase family protein 0.0015 0.0018 0.0017
Loa Loa (eye worm) hypothetical protein 0.0033 0.0092 0.017
Plasmodium vivax hypothetical protein, conserved 0.0033 0.0093 0.0468
Echinococcus multilocularis rhodopsin orphan GPCR 0.0033 0.0092 0.0092
Treponema pallidum fructose-bisphosphate aldolase 0.0292 0.116 1
Brugia malayi GTP-binding nuclear protein RAN/TC4 0.0023 0.0051 0.0095
Brugia malayi glutathione reductase 0.0037 0.0108 0.02
Mycobacterium ulcerans DNA polymerase IV 0.0039 0.0117 0.1042
Brugia malayi Inhibitor of Apoptosis domain containing protein 0.0053 0.0172 0.0318
Giardia lamblia Cathepsin B precursor 0.0136 0.0515 0.2516
Brugia malayi Protein kinase domain containing protein 0.0017 0.0026 0.0049
Trichomonas vaginalis ocrl type II inositol 5-phosphatase, putative 0.0015 0.0018 0.0045
Loa Loa (eye worm) hypothetical protein 0.0033 0.0092 0.017
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0033 0.0092 0.017
Brugia malayi Cathepsin L-like precursor 0.0463 0.1864 0.3443
Schistosoma mansoni neuropeptide receptor 0.0033 0.0092 0.017
Echinococcus multilocularis cathepsin L cysteine protease 0.0463 0.1864 0.1864
Echinococcus granulosus inositol monophosphatase 1 0.0072 0.025 0.0463
Brugia malayi Hemopexin family protein 0.0065 0.0222 0.041
Echinococcus granulosus importin subunit beta 1 0.0032 0.0086 0.0158
Trypanosoma brucei unspecified product 0.0027 0.0067 0.0303
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0033 0.0092 0.017
Echinococcus multilocularis G-protein coupled receptor, putative 0.0033 0.0092 0.0092
Loa Loa (eye worm) hypothetical protein 0.0039 0.0118 0.0218
Loa Loa (eye worm) hypothetical protein 0.0033 0.0093 0.0171
Echinococcus multilocularis orexin receptor type 2 0.0033 0.0092 0.0092
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.004 0.0119 0.0547
Brugia malayi G protein-coupled receptor 0.0033 0.0092 0.017
Echinococcus multilocularis pyruvate kinase 0.0017 0.0028 0.0028
Mycobacterium ulcerans esterase/lipase LipP 0.0039 0.0118 0.105
Echinococcus granulosus beta LACTamase domain containing family member 0.0039 0.0118 0.0218
Toxoplasma gondii inositol(myo)-1(or 4)-monophosphatase 2, putative 0.0072 0.025 0.1209
Brugia malayi mbt repeat family protein 0.0048 0.0155 0.0287
Toxoplasma gondii histone lysine-specific demethylase 0.0014 0.0015 0.0046
Mycobacterium ulcerans dehydrogenase 0.0014 0.0015 0.0088
Leishmania major RNA-editing complex protein MP100, putative 0.0015 0.0018 0.0058
Trypanosoma cruzi Inositol phosphosphingolipids phospholipase C 0.0015 0.0018 0.0022
Loa Loa (eye worm) hypothetical protein 0.0026 0.0063 0.0116
Trypanosoma brucei serine peptidase, clan SC, family S9A-like protein 0.0054 0.0179 0.0853
Brugia malayi dihydrolipoyl dehydrogenase, mitochondrial precursor, putative 0.0013 0.0009 0.0016
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0503 0.203 1
Onchocerca volvulus 0.0033 0.0092 0.0486
Echinococcus multilocularis cathepsin b 0.1324 0.5413 0.5413
Plasmodium falciparum serine repeat antigen 7 0.0136 0.0515 0.274
Brugia malayi putative neuropeptide receptor 0.0033 0.0092 0.017
Loa Loa (eye worm) pyruvate kinase 0.0034 0.0096 0.0177
Plasmodium vivax serine-repeat antigen 2 (SERA) 0.0136 0.0515 0.274
Echinococcus granulosus biogenic amine 5HT receptor 0.0033 0.0092 0.017
Schistosoma mansoni peptide (allatostatin)-like receptor 0.0033 0.0092 0.017
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD2 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0025 0.0059 0.047
Onchocerca volvulus 0.0463 0.1864 1
Schistosoma mansoni prolyl oligopeptidase (S09 family) 0.0014 0.0014 0.0027
Brugia malayi Endonuclease/Exonuclease/phosphatase family protein 0.0015 0.0018 0.0032
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0033 0.0092 0.017
Loa Loa (eye worm) hypothetical protein 0.0044 0.0136 0.025
Trypanosoma cruzi cysteine proteinase, putative 0.0203 0.0792 0.1454
Echinococcus multilocularis cathepsin L 0.0136 0.0515 0.0515
Trichomonas vaginalis esterase, putative 0.0039 0.0118 0.0542
Echinococcus multilocularis chromodomain helicase DNA binding protein 4 0.0035 0.0099 0.0099
Loa Loa (eye worm) hypothetical protein 0.0136 0.0516 0.0954
Schistosoma mansoni neuropeptide F-like receptor 0.0033 0.0092 0.017
Toxoplasma gondii cathepsin CPC2 0.0136 0.0515 0.2516
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0396 0.1587 0.7808
Brugia malayi Importin beta-1 subunit 0.0032 0.0086 0.0158
Echinococcus multilocularis glutamate receptor 4 0.0044 0.0136 0.0136
Schistosoma mansoni hypothetical protein 0.0053 0.0172 0.0318
Onchocerca volvulus 0.0033 0.0092 0.0486
Brugia malayi CXXC zinc finger family protein 0.0028 0.0072 0.0132
Trypanosoma cruzi cysteine peptidase, putative 0.0463 0.1864 0.3436
Echinococcus multilocularis snurportin 1 0.0337 0.1345 0.1345
Echinococcus granulosus neuropeptide Y receptor 0.0033 0.0092 0.017
Loa Loa (eye worm) gonadotropin-releasing hormone receptor 2 0.0033 0.0092 0.017
Mycobacterium leprae PROBABLE NADH DEHYDROGENASE NDH 0.0085 0.0304 0.5467
Loa Loa (eye worm) hypothetical protein 0.0136 0.0515 0.0951
Toxoplasma gondii exonuclease III APE 0.0074 0.0263 0.1269
Loa Loa (eye worm) hypothetical protein 0.0396 0.1587 0.2931
Brugia malayi Cathepsin L-like precursor 0.0463 0.1864 0.3443
Giardia lamblia Cathepsin B precursor 0.0136 0.0515 0.2516
Onchocerca volvulus Pyruvate kinase homolog 0.0034 0.0096 0.0508
Leishmania major pyruvate kinase 0.0034 0.0096 0.0445
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0033 0.0092 0.017
Trypanosoma brucei unspecified product 0.0039 0.0117 0.0551
Toxoplasma gondii chromodomain helicase DNA binding protein CHD1/SWI2/SNF2 0.0033 0.0093 0.043
Echinococcus multilocularis CCR4 NOT transcription complex subunit 6 0.0015 0.0018 0.0018
Echinococcus multilocularis chromobox protein 1 0.0033 0.0093 0.0093
Schistosoma mansoni biogenic amine receptor 0.0033 0.0092 0.017
Toxoplasma gondii GTP-binding nuclear protein ran/tc4 0.0023 0.0051 0.0225
Plasmodium falciparum serine repeat antigen 6 0.0136 0.0515 0.274
Leishmania major myo-inositol-1(or 4)-monophosphatase 1, putative 0.0072 0.025 0.1209
Trypanosoma brucei DNA polymerase eta, putative 0.0039 0.0117 0.0551
Brugia malayi Glutamate receptor 2 precursor 0.007 0.0242 0.0448
Echinococcus multilocularis alpha 1A adrenergic receptor 0.0033 0.0092 0.0092
Plasmodium vivax vivapain-3 0.0203 0.0792 0.4232
Echinococcus granulosus tachykinin peptides receptor 99D 0.0033 0.0092 0.017
Echinococcus granulosus lysine specific histone demethylase 1A 0.0071 0.0249 0.046
Trypanosoma cruzi cysteine peptidase, putative 0.0203 0.0792 0.1454
Echinococcus granulosus tissue type plasminogen activator 0.0017 0.0026 0.0049
Mycobacterium ulcerans long-chain-fatty-acid-CoA ligase 0.0025 0.0059 0.0495
Brugia malayi chromobox protein homolog 3 0.0033 0.0093 0.0171
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0067 0.0233 0.043
Plasmodium falciparum carbon catabolite repressor protein 4, putative 0.0015 0.0018 0.0063
Wolbachia endosymbiont of Brugia malayi fructose-1,6-bisphosphatase 0.0072 0.025 0.9523
Mycobacterium ulcerans acyl-CoA synthetase 0.0025 0.0059 0.0495
Trypanosoma cruzi DNA polymerase kappa, putative 0.0039 0.0117 0.0206
Plasmodium vivax serine-repeat antigen 5 (SERA) 0.0136 0.0515 0.274
Plasmodium falciparum pyruvate kinase 2 0.0017 0.0028 0.0118
Leishmania major importin beta-1 subunit, putative 0.0026 0.0061 0.0274
Trypanosoma brucei hypothetical protein, conserved 0.0039 0.0118 0.0555
Trypanosoma cruzi cysteine peptidase, clan CA, family C1, cathepsin L-like, putative 0.0396 0.1587 0.2924
Echinococcus multilocularis Chromobox protein 3 0.0033 0.0093 0.0093
Onchocerca volvulus 0.0033 0.0092 0.0486
Trichomonas vaginalis glucosylceramidase, putative 0.0254 0.1002 0.4917
Plasmodium vivax dipeptidyl aminopeptidase 3, putative 0.0136 0.0515 0.274
Trypanosoma brucei importin beta-1 subunit, putative 0.0032 0.0086 0.0395
Mycobacterium tuberculosis Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) 0.0074 0.0263 0.2381
Plasmodium vivax dipeptidyl aminopeptidase 1, putative 0.0136 0.0515 0.274
Echinococcus granulosus glutamate receptor 4 0.0044 0.0136 0.025
Loa Loa (eye worm) hypothetical protein 0.0136 0.0515 0.0951
Leishmania major cathepsin L-like protease 0.0463 0.1864 0.918
Onchocerca volvulus Prolyl endopeptidase homolog 0.0136 0.0516 0.2764
Trypanosoma brucei DNA polymerase kappa, putative 0.0039 0.0117 0.0551
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0013 0.0009 0.0014
Echinococcus granulosus tm gpcr rhodopsin 0.0033 0.0092 0.017
Trichomonas vaginalis conserved hypothetical protein 0.0033 0.0093 0.0417
Brugia malayi hypothetical protein 0.0106 0.039 0.0721
Brugia malayi Cytochrome P450 family protein 0.0019 0.0035 0.0065
Schistosoma mansoni chromobox protein-related (chromobox 1) (heterochromatin 1) 0.0033 0.0093 0.0171
Schistosoma mansoni ocrl type II inositol 5-phosphatase 0.0015 0.0018 0.0032
Schistosoma mansoni pyruvate kinase 0.0034 0.0096 0.0177
Schistosoma mansoni ap endonuclease 0.0074 0.0263 0.0485
Schistosoma mansoni intermediate filament proteins 0.0026 0.0065 0.0119
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.004 0.0119 0.0547
Trypanosoma cruzi dipeptidyl-peptidase 8-like serine peptidase 0.0014 0.0014 0.0016
Schistosoma mansoni cathepsin F (C01 family) 0.0463 0.1864 0.3443
Entamoeba histolytica cysteine protease, putative 0.0463 0.1864 1
Onchocerca volvulus 0.0463 0.1864 1
Toxoplasma gondii endonuclease/exonuclease/phosphatase family protein 0.0015 0.0018 0.0058
Loa Loa (eye worm) hypothetical protein 0.0033 0.0092 0.017
Trypanosoma cruzi apurinic/apyrimidinic endonuclease 0.0074 0.0263 0.0475
Plasmodium falciparum cysteine proteinase falcipain 3 0.0463 0.1864 1
Echinococcus granulosus g-protein coupled receptor 0.0033 0.0092 0.017
Trypanosoma cruzi DNA polymerase kappa, putative 0.0039 0.0117 0.0206
Brugia malayi Papain family cysteine protease containing protein 0.0136 0.0515 0.0951
Trypanosoma brucei DNA polymerase kappa, putative 0.0039 0.0117 0.0551
Echinococcus granulosus G protein coupled 5 hydroxytryptamine receptor 0.0033 0.0092 0.017
Schistosoma mansoni histamine-responsive GPCR (AAF21638) 0.0033 0.0092 0.017
Echinococcus multilocularis serotonin receptor 0.0033 0.0092 0.0092
Loa Loa (eye worm) hypothetical protein 0.0033 0.0092 0.017
Echinococcus granulosus chromobox protein 2 0.0571 0.2307 0.4262
Echinococcus granulosus Glutamate receptor ionotropic kainate 2 0.0031 0.0083 0.0153
Loa Loa (eye worm) hypothetical protein 0.0019 0.0033 0.006
Trichomonas vaginalis glucosylceramidase, putative 0.0254 0.1002 0.4917
Giardia lamblia Endonuclease/Exonuclease/phosphatase 0.0074 0.0263 0.1269
Echinococcus granulosus chromodomain helicase DNA binding protein 4 0.0035 0.0099 0.0184
Loa Loa (eye worm) endonuclease/Exonuclease/phosphatase 0.0015 0.0018 0.0032
Trypanosoma brucei DNA polymerase kappa, putative 0.0039 0.0117 0.0551
Plasmodium vivax hypothetical protein, conserved 0.0014 0.0015 0.0051
Echinococcus multilocularis baculoviral IAP repeat containing protein 0.0053 0.0172 0.0172
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0033 0.0093 0.0417
Echinococcus multilocularis dipeptidyl aminopeptidaseprotein 0.0014 0.0014 0.0014
Loa Loa (eye worm) hypothetical protein 0.0053 0.0172 0.0318
Brugia malayi Cathepsin L-like precursor 0.0463 0.1864 0.3443
Echinococcus multilocularis cytoplasmic intermediate filament protein 0.0013 0.0008 0.0008
Brugia malayi Unidentified vitellogenin-linked transcript protein 6, putative 0.0033 0.0092 0.017
Echinococcus granulosus dna polymerase eta 0.0039 0.0117 0.0217
Loa Loa (eye worm) hypothetical protein 0.0053 0.0172 0.0318
Schistosoma mansoni aldehyde dehydrogenase 0.0178 0.069 0.1275
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0136 0.0515 0.2505
Schistosoma mansoni myelin transcription factor 1 myt1 0.0055 0.0183 0.0338
Onchocerca volvulus 0.0396 0.1587 0.8512
Brugia malayi exodeoxyribonuclease III family protein 0.0074 0.0263 0.0485
Schistosoma mansoni adenoreceptor 0.0033 0.0092 0.017
Trichomonas vaginalis conserved hypothetical protein 0.0037 0.0107 0.0487
Schistosoma mansoni ancient conserved domain protein 2 (cyclin m2) 0.0033 0.0092 0.017
Plasmodium falciparum cysteine proteinase falcipain 2b 0.0463 0.1864 1
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0463 0.1864 0.918
Echinococcus granulosus cathepsin l1 0.0396 0.1587 0.2931
Loa Loa (eye worm) hypothetical protein 0.0033 0.0092 0.017
Trypanosoma cruzi pantothenate kinase subunit, putative 0.0016 0.0022 0.003
Entamoeba histolytica cysteine proteinase 1, putative 0.0203 0.0792 0.4205
Mycobacterium ulcerans long-chain fatty-acid CoA ligase 0.0025 0.0059 0.0495
Loa Loa (eye worm) hypothetical protein 0.0046 0.0144 0.0265
Loa Loa (eye worm) hypothetical protein 0.0033 0.0092 0.017
Entamoeba histolytica cysteine protease, putative 0.0203 0.0792 0.4205
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative 0.0074 0.0263 0.1269
Echinococcus granulosus rhodopsin orphan GPCR 0.0033 0.0092 0.017
Leishmania major apurinic/apyrimidinic endonuclease-redox protein 0.0074 0.0263 0.1269
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.0203 0.0792 0.1463
Mycobacterium ulcerans short chain dehydrogenase 0.0272 0.1075 1
Echinococcus multilocularis suppression of tumorigenicity 18 protein 0.0055 0.0183 0.0183
Loa Loa (eye worm) TYRA-2 protein 0.0033 0.0092 0.017
Echinococcus granulosus muscleblind protein 0.0149 0.0569 0.1051
Leishmania major cathepsin L-like protease 0.0463 0.1864 0.918
Echinococcus multilocularis acylamino acid releasing enzyme 0.0014 0.0014 0.0014
Schistosoma mansoni glutamate receptor kainate 0.0026 0.0062 0.0115
Echinococcus multilocularis g-protein coupled receptor 0.0033 0.0092 0.0092
Brugia malayi POT family protein 0.004 0.0118 0.0219
Echinococcus multilocularis dna polymerase eta 0.0039 0.0117 0.0117
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.0203 0.0792 0.1463
Echinococcus granulosus baculoviral IAP repeat containing protein 0.0053 0.0172 0.0318
Loa Loa (eye worm) endonuclease/Exonuclease/phosphatase 0.0015 0.0018 0.0032
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0292 0.116 0.5696
Plasmodium vivax dipeptidyl aminopeptidase 2, putative 0.0136 0.0515 0.274
Loa Loa (eye worm) hypothetical protein 0.0149 0.0569 0.1051
Giardia lamblia Cathepsin B precursor 0.0503 0.203 1
Loa Loa (eye worm) hypothetical protein 0.0033 0.0093 0.0171
Leishmania major cathepsin L-like protease 0.0463 0.1864 0.918
Trypanosoma cruzi serine peptidase, Clan SC, Family S9B 0.0014 0.0014 0.0016
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0463 0.1864 0.9179
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0292 0.116 0.5696
Schistosoma mansoni hypothetical protein 0.0033 0.0092 0.017
Giardia lamblia Cathepsin B precursor 0.0136 0.0515 0.2516
Onchocerca volvulus 0.0015 0.0018 0.0087
Entamoeba histolytica cysteine protease, putative 0.0203 0.0792 0.4205
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.0463 0.1864 0.9179
Brugia malayi cathepsin Z-like cysteine proteinase 0.0136 0.0515 0.0951
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.0015 0.0018 0.0022
Loa Loa (eye worm) hypothetical protein 0.0033 0.0092 0.017
Brugia malayi Papain family cysteine protease containing protein 0.0136 0.0515 0.0951
Onchocerca volvulus 0.0026 0.0065 0.034
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0231 0.0906 0.0906
Loa Loa (eye worm) mbt repeat family protein 0.0048 0.0155 0.0287
Echinococcus multilocularis Glutamate receptor, ionotropic kainate 2 0.0031 0.0083 0.0083
Mycobacterium ulcerans pyruvate kinase 0.0034 0.0096 0.0843
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD7 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0025 0.0059 0.0823
Brugia malayi hypothetical protein 0.0068 0.0236 0.0437
Echinococcus granulosus inositol polyphosphate 5 phosphatase OCRL 1 0.0015 0.0018 0.0032
Echinococcus granulosus glutamate receptor 2 0.0065 0.0223 0.0412
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0136 0.0515 0.0951
Echinococcus granulosus cathepsin L cysteine proteinase 0.0463 0.1864 0.3443
Entamoeba histolytica papain family cysteine protease domain containing protein 0.0136 0.0515 0.2707
Loa Loa (eye worm) latrophilin receptor protein 2 0.0126 0.0474 0.0876
Brugia malayi Inositol-1 0.0072 0.025 0.0463
Schistosoma mansoni neuropeptide receptor 0.0033 0.0092 0.017
Onchocerca volvulus 0.0028 0.0072 0.0378
Entamoeba histolytica deoxycytidyl transferase, putative 0.0039 0.0117 0.0556
Plasmodium vivax serine-repeat antigen 3 (SERA) 0.0136 0.0515 0.274
Schistosoma mansoni nocturnin 0.0015 0.0018 0.0032
Mycobacterium tuberculosis Probable reductase 0.0085 0.0304 0.2772
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0136 0.0515 0.0951
Echinococcus multilocularis cathepsin l cysteine peptidase 0.0463 0.1864 0.1864
Trypanosoma cruzi cruzipain precursor, putative 0.0463 0.1864 0.3436
Schistosoma mansoni carbon catabolite repressor protein 0.0015 0.0018 0.0032
Brugia malayi Endonuclease/Exonuclease/phosphatase family protein 0.0015 0.0018 0.0032
Echinococcus granulosus aldehyde dehydrogenase mitochondrial 0.0178 0.069 0.1275
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.004 0.0119 0.0547
Mycobacterium tuberculosis Conserved protein 0.0039 0.0118 0.1027
Echinococcus granulosus pyruvate kinase 0.0017 0.0028 0.0051
Loa Loa (eye worm) cytoplasmic intermediate filament protein 0.0014 0.0014 0.0026
Echinococcus granulosus chromobox protein 1 0.0033 0.0093 0.0171
Entamoeba histolytica cysteine proteinase, putative 0.0463 0.1864 1
Giardia lamblia Dipeptidyl-peptidase I precursor 0.0136 0.0515 0.2516
Plasmodium vivax exodeoxyribonuclease III, putative 0.0015 0.0018 0.0063
Onchocerca volvulus 0.0077 0.0274 0.1462
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0033 0.0093 0.0417
Plasmodium falciparum glutathione reductase 0.0013 0.0009 0.0015
Schistosoma mansoni inhibitor of apoptosis protein 0.0053 0.0172 0.0318
Trypanosoma brucei trypanothione reductase 0.0037 0.0108 0.0507
Loa Loa (eye worm) hypothetical protein 0.0033 0.0092 0.017
Trypanosoma brucei prolyl endopeptidase 0.0136 0.0516 0.2522
Schistosoma mansoni inositol monophosphatase 0.0072 0.025 0.0463
Echinococcus granulosus neuropeptide receptor 0.0033 0.0092 0.017
Mycobacterium tuberculosis Probable protease II PtrBa [first part] (oligopeptidase B) 0.0122 0.0457 0.4207
Echinococcus multilocularis importin subunit beta 1 0.0032 0.0086 0.0086
Echinococcus granulosus dipeptidyl aminopeptidaseprotein 0.0014 0.0014 0.0027
Onchocerca volvulus 0.0039 0.0118 0.0627
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0126 0.0474 0.0876
Loa Loa (eye worm) cytochrome P450 family protein 0.0019 0.0035 0.0065
Mycobacterium ulcerans hydrolase 0.0056 0.0185 0.1671
Loa Loa (eye worm) hypothetical protein 0.0033 0.0092 0.017
Loa Loa (eye worm) hypothetical protein 0.0015 0.0018 0.0032
Brugia malayi hypothetical protein 0.0014 0.0015 0.0028
Trichomonas vaginalis type IV inositol 5-phosphatase, putative 0.0015 0.0018 0.0045
Echinococcus granulosus cathepsin l cysteine peptidase 0.0463 0.1864 0.3443
Onchocerca volvulus 0.0039 0.0118 0.0627
Trichomonas vaginalis conserved hypothetical protein 0.0033 0.0093 0.0417
Loa Loa (eye worm) heterochromatin protein 1 0.0033 0.0093 0.0171
Echinococcus granulosus neuropeptide FF receptor 2 0.0253 0.0997 0.1843
Loa Loa (eye worm) hypothetical protein 0.0024 0.0053 0.0099
Brugia malayi AMP-binding enzyme family protein 0.0025 0.0059 0.0108
Giardia lamblia Cathepsin B precursor 0.0503 0.203 1
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.004 0.0119 0.0547
Mycobacterium ulcerans DNA polymerase IV 0.0039 0.0117 0.1042
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0126 0.0474 0.0474
Trypanosoma cruzi hypothetical protein, conserved 0.0017 0.0026 0.0038
Entamoeba histolytica pyruvate kinase, putative 0.0024 0.0053 0.0211
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0136 0.0515 0.2505
Echinococcus granulosus matrix metallopeptidase 7 M10 family 0.0166 0.0639 0.1181
Trypanosoma cruzi major cysteine proteinase, putative 0.0136 0.0515 0.0942
Schistosoma mansoni alpha-1 adrenergic receptor 0.0033 0.0092 0.017
Loa Loa (eye worm) hypothetical protein 0.0272 0.1077 0.1989
Trichomonas vaginalis glucosylceramidase, putative 0.0167 0.0642 0.3136
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0013 0.0009 0.0014
Echinococcus granulosus biogenic amine 5HT receptor 0.0033 0.0092 0.017
Schistosoma mansoni cathepsin B (C01 family) 0.0136 0.0515 0.0951
Echinococcus multilocularis chromobox protein 1 0.0033 0.0093 0.0093
Trichomonas vaginalis carbon catabolite repressor protein, putative 0.0015 0.0018 0.0045
Plasmodium vivax hypothetical protein, conserved 0.0014 0.0015 0.0051
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0035 0.0099 0.0447
Echinococcus multilocularis 7TM GPCR, rhodopsin 0.0033 0.0092 0.0092
Echinococcus multilocularis neuropeptide receptor 0.0033 0.0092 0.0092
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0463 0.1864 0.918
Loa Loa (eye worm) hypothetical protein 0.0033 0.0092 0.017
Plasmodium falciparum ataxin-2 like protein, putative 0.0106 0.039 0.207
Onchocerca volvulus Polycomb protein Sfmbt homolog 0.0048 0.0155 0.0826
Echinococcus multilocularis Ataxin 2, N terminal,domain containing protein 0.0047 0.0151 0.0151
Plasmodium falciparum dipeptidyl aminopeptidase 3 0.0136 0.0515 0.274
Brugia malayi putative neuropeptide receptor NPR1 0.0033 0.0092 0.017
Trypanosoma brucei GTP-binding nuclear protein rtb2, putative 0.0023 0.0051 0.0225
Plasmodium vivax glutathione reductase, putative 0.0037 0.0108 0.0553
Plasmodium vivax unspecified product 0.0067 0.0233 0.1222
Echinococcus granulosus dna polymerase kappa 0.0039 0.0117 0.0217
Mycobacterium ulcerans flavin-containing monoamine oxidase AofH 0.0014 0.0015 0.0088
Schistosoma mansoni myosin xvIII 0.0033 0.0092 0.017
Schistosoma mansoni neuropeptide f receptor 76f 0.0033 0.0092 0.017
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0072 0.025 0.0453
Giardia lamblia Cysteine protease 0.0136 0.0515 0.2516
Trypanosoma brucei DNA polymerase IV, putative 0.0039 0.0117 0.0551
Echinococcus granulosus g protein coupled receptor 0.0033 0.0092 0.017
Brugia malayi RE15519p 0.0033 0.0092 0.017
Schistosoma mansoni cpg binding protein 0.003 0.0078 0.0145
Echinococcus granulosus inhibitor of apoptosis protein 0.0053 0.0172 0.0318
Toxoplasma gondii ABC1 family protein 0.0039 0.0118 0.0555
Plasmodium falciparum dihydrolipoyl dehydrogenase, mitochondrial 0.0013 0.0009 0.0015
Mycobacterium leprae conserved hypothetical protein 0.0039 0.0118 0.1947
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0503 0.203 0.375
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.0292 0.116 0.6194
Brugia malayi Endonuclease/Exonuclease/phosphatase family protein 0.0015 0.0018 0.0032
Brugia malayi Serotonin receptor 0.0033 0.0092 0.017
Trypanosoma brucei serine peptidase, Clan SC, Family S9B 0.0014 0.0014 0.0043
Brugia malayi beta-lactamase 0.0039 0.0118 0.0218
Toxoplasma gondii endonuclease/exonuclease/phosphatase family protein 0.0015 0.0018 0.0058
Loa Loa (eye worm) hypothetical protein 0.0019 0.0033 0.006
Echinococcus granulosus geminin 0.0678 0.2749 0.5078
Echinococcus granulosus Chromobox protein 3 0.0033 0.0093 0.0171
Loa Loa (eye worm) unidentified vitellogenin-linked transcript protein 6 0.0033 0.0092 0.017
Echinococcus granulosus snurportin 1 0.0337 0.1345 0.2485
Giardia lamblia Cysteine protease 0.0136 0.0515 0.2516
Schistosoma mansoni neuropeptide receptor 0.0033 0.0092 0.017
Trypanosoma brucei RNA editing exonuclease 2 0.0015 0.0018 0.0058
Schistosoma mansoni hypothetical protein 0.0033 0.0092 0.017
Plasmodium vivax GTP-binding nuclear protein RAN/TC4, putative 0.0023 0.0051 0.0245
Loa Loa (eye worm) hypothetical protein 0.0044 0.0136 0.025
Echinococcus multilocularis Glutamate receptor, ionotropic kainate 2 0.0031 0.0083 0.0083
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0033 0.0092 0.017
Schistosoma mansoni cpg binding protein 0.0028 0.0072 0.0132
Schistosoma mansoni SmCB2 peptidase (C01 family) 0.1324 0.5413 1
Echinococcus granulosus traf and tnf receptor associated protein 0.0015 0.0018 0.0032
Trypanosoma cruzi UDP-galactopyranose mutase 0.0014 0.0015 0.0017
Brugia malayi cytoplasmic intermediate filament protein 0.0014 0.0014 0.0026
Schistosoma mansoni dipeptidyl-peptidase 9 (S09 family) 0.0014 0.0014 0.0027
Loa Loa (eye worm) hypothetical protein 0.0039 0.0118 0.0218
Mycobacterium leprae DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE 0.0094 0.0343 0.6203
Leishmania major prolyl oligopeptidase, putative,serine peptidase clan SC, family S9A, putative 0.0136 0.0516 0.2522
Loa Loa (eye worm) melatonin receptor type 1A 0.0033 0.0092 0.017
Schistosoma mansoni acylaminoacyl-peptidase (S09 family) 0.0014 0.0014 0.0027
Echinococcus multilocularis cathepsin l cysteine peptidase 0.0463 0.1864 0.1864
Loa Loa (eye worm) hypothetical protein 0.0052 0.0171 0.0315
Mycobacterium tuberculosis Probable NADH dehydrogenase Ndh 0.0085 0.0304 0.2772
Schistosoma mansoni terminal deoxycytidyl transferase 0.0039 0.0117 0.0217
Trypanosoma cruzi DNA polymerase kappa, putative 0.0039 0.0117 0.0206
Trypanosoma cruzi Endonuclease/Exonuclease/phosphatase family, putative 0.0015 0.0018 0.0022
Brugia malayi SWIRM domain containing protein 0.0077 0.0274 0.0505
Loa Loa (eye worm) hypothetical protein 0.0033 0.0092 0.017
Echinococcus granulosus terminal deoxycytidyl transferase rev1 0.0039 0.0117 0.0217
Onchocerca volvulus Cathepsin F homolog 0.0463 0.1864 1
Schistosoma mansoni amine GPCR 0.0033 0.0092 0.017
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0203 0.0792 0.3877
Brugia malayi hypothetical protein 0.0033 0.0092 0.017
Brugia malayi cathepsin F-like cysteine proteinase 0.0067 0.0233 0.043
Mycobacterium tuberculosis Probable lipase LipE 0.0039 0.0118 0.1027
Echinococcus granulosus rhodopsin orphan GPCR 0.0033 0.0092 0.017
Loa Loa (eye worm) hypothetical protein 0.0019 0.0033 0.006
Plasmodium vivax pyruvate kinase, putative 0.0034 0.0096 0.0485
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0036 0.0105 0.0477
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0033 0.0092 0.0092
Brugia malayi cathepsin F-like cysteine proteinase 0.0136 0.0515 0.0951
Loa Loa (eye worm) follicle stimulating hormone receptor 0.0033 0.0092 0.017
Plasmodium falciparum conserved Plasmodium protein, unknown function 0.0014 0.0015 0.0051
Brugia malayi hypothetical protein 0.0033 0.0092 0.017
Loa Loa (eye worm) hypothetical protein 0.0033 0.0092 0.017
Leishmania major pyruvate kinase 0.0034 0.0096 0.0445
Trichomonas vaginalis chromobox protein, putative 0.0033 0.0093 0.0417
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0203 0.0792 0.3877
Schistosoma mansoni voltage-gated potassium channel 0.0041 0.0123 0.0227
Echinococcus multilocularis aldehyde dehydrogenase, mitochondrial 0.0178 0.069 0.069
Brugia malayi fibroinase precursor 0.0136 0.0515 0.0951
Loa Loa (eye worm) cytochrome P450 family protein 0.0019 0.0035 0.0065
Mycobacterium tuberculosis Possible DNA-damage-inducible protein P DinP (DNA polymerase V) (pol IV 2) (DNA nucleotidyltransferase (DNA-directed)) 0.0039 0.0117 0.1019
Entamoeba histolytica cysteine protease, putative 0.0203 0.0792 0.4205
Entamoeba histolytica chromodomain-helicase-DNA-binding protein, putative 0.0033 0.0093 0.0424
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0463 0.1864 0.918
Echinococcus multilocularis GTP binding nuclear protein Ran 0.0023 0.0051 0.0051
Mycobacterium ulcerans aldehyde dehydrogenase 0.0178 0.069 0.6396
Trypanosoma brucei oligopeptidase b 0.0054 0.0179 0.0853
Echinococcus multilocularis prolyl endopeptidase 0.0136 0.0516 0.0516
Plasmodium vivax serine-repeat antigen (SERA), putative 0.0136 0.0515 0.274
Brugia malayi sulfakinin receptor protein 0.0033 0.0092 0.017
Trypanosoma brucei pyruvate kinase 1, putative 0.0034 0.0096 0.0445
Echinococcus multilocularis histone acetyltransferase MYST2 0.0055 0.0183 0.0183
Onchocerca volvulus 0.0033 0.0093 0.0491
Echinococcus granulosus cpg binding protein 0.003 0.0078 0.0145
Loa Loa (eye worm) hypothetical protein 0.0136 0.0515 0.0951
Echinococcus multilocularis tumor protein p63 0.0356 0.1425 0.1425
Mycobacterium leprae possible inositol monophosphatase SubH (IMPase) (inositol-1-phosphatase) (I-1-Pase ). 0.0064 0.022 0.3866
Loa Loa (eye worm) hypothetical protein 0.0033 0.0092 0.017
Trichomonas vaginalis hypothetical protein 0.0033 0.0093 0.0417
Plasmodium falciparum serine repeat antigen 2 0.0136 0.0515 0.274
Brugia malayi M-phase phosphoprotein, mpp8 0.0033 0.0093 0.0171
Plasmodium falciparum serine repeat antigen 1 0.0136 0.0515 0.274
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD5 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0018 0.0028 0.0186
Plasmodium falciparum endonuclease/exonuclease/phosphatase family protein, putative 0.0015 0.0018 0.0063
Plasmodium vivax thioredoxin reductase, putative 0.0037 0.0108 0.0553
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0231 0.0906 0.1674
Echinococcus granulosus peptide allatostatin:somatostatin 0.0033 0.0092 0.017
Loa Loa (eye worm) ctsf protein 0.0463 0.1864 0.3443
Brugia malayi hypothetical protein 0.0033 0.0092 0.017
Loa Loa (eye worm) 5-hydroxytryptamine 2C receptor 0.0033 0.0092 0.017
Loa Loa (eye worm) transcription factor SMAD2 0.0116 0.0432 0.0798
Echinococcus multilocularis Dipeptidyl peptidase 9 0.0014 0.0014 0.0014
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0072 0.025 0.0453
Loa Loa (eye worm) hypothetical protein 0.0014 0.0015 0.0028
Leishmania major hypothetical protein, conserved 0.0017 0.0026 0.0101
Echinococcus multilocularis rhodopsin orphan GPCR 0.0033 0.0092 0.0092
Giardia lamblia Fructose-bisphosphate aldolase 0.0292 0.116 0.5702
Loa Loa (eye worm) thioredoxin reductase 0.0037 0.0108 0.02
Plasmodium falciparum acyl-CoA synthetase 0.0019 0.0033 0.0144
Mycobacterium tuberculosis Inositol-1-monophosphatase SuhB 0.0064 0.022 0.1978
Trypanosoma cruzi cysteine peptidase, putative 0.0463 0.1864 0.3436
Schistosoma mansoni amine GPCR 0.0033 0.0092 0.017
Brugia malayi Cytochrome P450 family protein 0.0049 0.0156 0.0288
Schistosoma mansoni mixed-lineage leukemia protein mll 0.006 0.0202 0.0373
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.004 0.0119 0.0547
Mycobacterium tuberculosis Possible oxidoreductase 0.0014 0.0015 0.0062
Mycobacterium tuberculosis Probable oxidoreductase 0.0272 0.1075 1
Trichomonas vaginalis glucosylceramidase, putative 0.0254 0.1002 0.4917
Loa Loa (eye worm) hypothetical protein 0.0033 0.0093 0.0171
Echinococcus granulosus fmrfamide receptor 0.0033 0.0092 0.017
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0072 0.025 0.1197
Schistosoma mansoni biogenic amine (5HT) receptor 0.0033 0.0092 0.017
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0231 0.0906 0.1674
Trichomonas vaginalis Clan CA, family C1, cathepsin F-like cysteine peptidase 0.0136 0.0515 0.2505
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0033 0.0092 0.017
Brugia malayi prolyl oligopeptidase family protein 0.0136 0.0516 0.0954
Loa Loa (eye worm) hypothetical protein 0.0015 0.0018 0.0032
Echinococcus multilocularis potassium voltage gated channel subfamily H 0.0037 0.0109 0.0109
Echinococcus multilocularis musashi 0.0026 0.0065 0.0065
Mycobacterium tuberculosis Probable conserved lipoprotein 0.0039 0.0118 0.1027
Trichomonas vaginalis glucosylceramidase, putative 0.0167 0.0642 0.3136
Trichomonas vaginalis pyruvate kinase, putative 0.0034 0.0096 0.0432
Brugia malayi Type III restriction enzyme, res subunit family protein 0.0033 0.0093 0.0171
Mycobacterium ulcerans acyl-CoA synthetase 0.0025 0.0059 0.0495
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.004 0.0119 0.0547
Toxoplasma gondii pyruvate kinase PyK1 0.0034 0.0096 0.0445
Treponema pallidum exodeoxyribonuclease (exoA) 0.0074 0.0263 0.2206
Trichomonas vaginalis D-aminoacylase, putative 0.0039 0.0118 0.0542
Schistosoma mansoni growth hormone secretagogue receptor 0.0033 0.0092 0.017
Mycobacterium ulcerans hypothetical protein 0.0025 0.0059 0.0495
Schistosoma mansoni chromobox protein-related (chromobox 1) (heterochromatin 1) 0.0033 0.0093 0.0171
Loa Loa (eye worm) hypothetical protein 0.0033 0.0092 0.017
Loa Loa (eye worm) hypothetical protein 0.0046 0.0144 0.0265
Brugia malayi Serotonin/octopamine receptor family protein 7 0.0033 0.0092 0.017
Onchocerca volvulus Dopamine\/Ecdysteroid receptor homolog 0.0033 0.0092 0.0486
Brugia malayi Endonuclease/Exonuclease/phosphatase family protein 0.0015 0.0018 0.0032
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0033 0.0092 0.0092
Echinococcus multilocularis Chromo domain 0.0033 0.0093 0.0093
Echinococcus multilocularis glutamate receptor 2 0.007 0.0242 0.0242
Echinococcus multilocularis rhodopsin orphan GPCR 0.0033 0.0092 0.0092
Echinococcus multilocularis traf and tnf receptor associated protein 0.0015 0.0018 0.0018
Brugia malayi Endonuclease/Exonuclease/phosphatase family protein 0.0015 0.0018 0.0032
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0039 0.0118 0.0218
Onchocerca volvulus 0.0053 0.0172 0.0917
Loa Loa (eye worm) hypothetical protein 0.0017 0.0026 0.0049
Schistosoma mansoni importin beta-1 0.0032 0.0086 0.0158
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0136 0.0515 0.2505
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0126 0.0474 0.0876
Trichomonas vaginalis conserved hypothetical protein 0.0033 0.0093 0.0417
Trypanosoma brucei DNA polymerase kappa, putative 0.0027 0.0067 0.0303
Leishmania major oligopeptidase B-like protein,serine peptidase, clan SC, family S9A-like protein 0.0054 0.0179 0.0853
Brugia malayi follicle stimulating hormone receptor 0.0033 0.0092 0.017
Schistosoma mansoni glutamate receptor NMDA 0.0026 0.0062 0.0115
Echinococcus granulosus glutamate receptor subunit protein glur 0.0053 0.0175 0.0323

Activities

Activity type Activity value Assay description Source Reference
ED50 (functional) = 1.7 mg kg-1 Inhibition of passive cutaneous anaphylaxis (PCA) in Charles Rivers Sprague-Dawley rat after intravenous administration; value range from 0.9 to 5.2 ChEMBL. 6131133

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

No external resources registered for this compound

Bibliographic References

1 literature reference was collected for this gene.

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