Detailed information for compound 1391409

Basic information

Technical information
  • TDR Targets ID: 1391409
  • Name: 4-cyclohexyl-N-(2-phenylethyl)piperazine-1-ca rbothioamide
  • MW: 331.519 | Formula: C19H29N3S
  • H donors: 1 H acceptors: 0 LogP: 3.73 Rotable bonds: 6
    Rule of 5 violations (Lipinski): 1
  • SMILES: S=C(N1CCN(CC1)C1CCCCC1)NCCc1ccccc1
  • InChi: 1S/C19H29N3S/c23-19(20-12-11-17-7-3-1-4-8-17)22-15-13-21(14-16-22)18-9-5-2-6-10-18/h1,3-4,7-8,18H,2,5-6,9-16H2,(H,20,23)
  • InChiKey: BMWAMIWHGALSRH-UHFFFAOYSA-N  


Substructure search Similarity search

Network

Hover on a compound node to display the structore

Synonyms

  • 4-cyclohexyl-N-(2-phenylethyl)-1-piperazinecarbothioamide
  • IVK/4006939
  • MLS000684385
  • SMR000295952
  • Oprea1_217332

Targets

Known targets for this compound

Species Target name Source Bibliographic reference
Homo sapiens lysine (K)-specific methyltransferase 2A Starlite/ChEMBL No references
Homo sapiens geminin, DNA replication inhibitor Starlite/ChEMBL No references
Homo sapiens isocitrate dehydrogenase 1 (NADP+), soluble Starlite/ChEMBL No references

Predicted pathogen targets for this compound

By orthology
Species Potential target Known druggable target/s Ortholog Group
Neospora caninum Isocitrate dehydrogenase-like protein, related Get druggable targets OG5_127057 All targets in OG5_127057
Plasmodium berghei isocitrate dehydrogenase [NADP], mitochondrial, putative Get druggable targets OG5_127057 All targets in OG5_127057
Trypanosoma congolense isocitrate dehydrogenase, putative Get druggable targets OG5_127057 All targets in OG5_127057
Mycobacterium tuberculosis Probable isocitrate dehydrogenase [NADP] Icd1 (oxalosuccinate decarboxylase) (IDH) (NADP+-specific ICDH) (IDP) Get druggable targets OG5_127057 All targets in OG5_127057
Candida albicans Mitochondrial NADP-specific isocitrate dehydrogenase Get druggable targets OG5_127057 All targets in OG5_127057
Plasmodium vivax isocitrate dehydrogenase [NADP], mitochondrial, putative Get druggable targets OG5_127057 All targets in OG5_127057
Trypanosoma congolense isocitrate dehydrogenase, putative Get druggable targets OG5_127057 All targets in OG5_127057
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase Get druggable targets OG5_127057 All targets in OG5_127057
Plasmodium knowlesi isocitrate dehydrogenase [NADP], mitochondrial, putative Get druggable targets OG5_127057 All targets in OG5_127057
Echinococcus multilocularis isocitrate dehydrogenase 2 (NADP+) Get druggable targets OG5_127057 All targets in OG5_127057
Brugia malayi isocitrate dehydrogenase Get druggable targets OG5_127057 All targets in OG5_127057
Candida albicans N terminus of cytosolic NADP-specific isocitrate dehydrogenase. Get druggable targets OG5_127057 All targets in OG5_127057
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase Get druggable targets OG5_127057 All targets in OG5_127057
Candida albicans cytosolic NADP-specific isocitrate dehydrogenase. Get druggable targets OG5_127057 All targets in OG5_127057
Trypanosoma cruzi isocitrate dehydrogenase, putative Get druggable targets OG5_127057 All targets in OG5_127057
Schistosoma mansoni mixed-lineage leukemia protein mll Get druggable targets OG5_130642 All targets in OG5_130642
Candida albicans Mitochondrial NADP-specific isocitrate dehydrogenase Get druggable targets OG5_127057 All targets in OG5_127057
Plasmodium yoelii isocitrate dehydrogenase, NADP-dependent Get druggable targets OG5_127057 All targets in OG5_127057
Leishmania braziliensis isocitrate dehydrogenase [NADP], mitochondrial precursor, putative Get druggable targets OG5_127057 All targets in OG5_127057
Leishmania infantum isocitrate dehydrogenase [NADP], mitochondrial precursor, putative Get druggable targets OG5_127057 All targets in OG5_127057
Schistosoma japonicum ko:K09188 myeloid/lymphoid or mixed-lineage leukemia protein 3, putative Get druggable targets OG5_130642 All targets in OG5_130642
Toxoplasma gondii isocitrate dehydrogenase Get druggable targets OG5_127057 All targets in OG5_127057
Candida albicans C terminus of cytosolic NADP-specific isocitrate dehydrogenase. Get druggable targets OG5_127057 All targets in OG5_127057
Leishmania major isocitrate dehydrogenase [NADP], mitochondrial precursor, putative Get druggable targets OG5_127057 All targets in OG5_127057
Echinococcus multilocularis isocitrate dehydrogenase Get druggable targets OG5_127057 All targets in OG5_127057
Trypanosoma brucei gambiense isocitrate dehydrogenase, putative Get druggable targets OG5_127057 All targets in OG5_127057
Schistosoma mansoni NADP-specific isocitrate dehydrogenase Get druggable targets OG5_127057 All targets in OG5_127057
Schistosoma japonicum ko:K00031 isocitrate dehydrogenase [EC1.1.1.42], putative Get druggable targets OG5_127057 All targets in OG5_127057
Trypanosoma brucei isocitrate dehydrogenase, putative Get druggable targets OG5_127057 All targets in OG5_127057
Plasmodium falciparum isocitrate dehydrogenase [NADP], mitochondrial Get druggable targets OG5_127057 All targets in OG5_127057
Neospora caninum hypothetical protein Get druggable targets OG5_127057 All targets in OG5_127057
Loa Loa (eye worm) isocitrate dehydrogenase Get druggable targets OG5_127057 All targets in OG5_127057
Plasmodium yoelii isocitrate dehydrogenase, NADP-dependent, putative Get druggable targets OG5_127057 All targets in OG5_127057
Trypanosoma cruzi isocitrate dehydrogenase [NADP], mitochondrial precursor, putative Get druggable targets OG5_127057 All targets in OG5_127057
Neospora caninum Multidomain chromatinic protein with the following architecture: 3x PHD-bromo-3xPHD-SET domain and associated cysteine cluster a Get druggable targets OG5_130642 All targets in OG5_130642
Trypanosoma brucei isocitrate dehydrogenase [NADP], mitochondrial precursor, putative Get druggable targets OG5_127057 All targets in OG5_127057
Trypanosoma brucei gambiense isocitrate dehydrogenase [NADP], mitochondrial precursor, putative Get druggable targets OG5_127057 All targets in OG5_127057
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase Get druggable targets OG5_127057 All targets in OG5_127057
Theileria parva isocitrate dehydrogenase (NADP+), putative Get druggable targets OG5_127057 All targets in OG5_127057
Leishmania donovani isocitrate dehydrogenase [NADP], mitochondrial precursor, putative Get druggable targets OG5_127057 All targets in OG5_127057
Toxoplasma gondii histone lysine methyltransferase SET1 Get druggable targets OG5_130642 All targets in OG5_130642
Babesia bovis isocitrate dehydrogenase, NADP-dependent family protein Get druggable targets OG5_127057 All targets in OG5_127057
Leishmania mexicana isocitrate dehydrogenase [NADP], mitochondrial precursor, putative Get druggable targets OG5_127057 All targets in OG5_127057
Toxoplasma gondii isocitrate dehydrogenase Get druggable targets OG5_127057 All targets in OG5_127057
Brugia malayi Isocitrate dehydrogenase Get druggable targets OG5_127057 All targets in OG5_127057
Echinococcus granulosus NADP dependent isocitrate dehydrogenase Get druggable targets OG5_127057 All targets in OG5_127057
By sequence similarity to non orthologous known druggable targets
Species Potential target Known druggable target Length Alignment span Identity
Brugia malayi Hypothetical 65.5 kDa Trp-Asp repeats containing protein F02E8.5 inchromosome X geminin, DNA replication inhibitor 209 aa 176 aa 27.8 %
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Trichomonas vaginalis bromodomain-containing protein, putative 0.0009 0.0009 0.0005
Loa Loa (eye worm) hypothetical protein 0.0009 0.0009 0.0009
Trichomonas vaginalis glutamate synthase, putative 0.0023 0.0183 0.0179
Schistosoma mansoni bromodomain containing protein 0.0074 0.0805 0.0805
Plasmodium vivax ferrodoxin reductase, putative 0.0023 0.0183 0.0574
Treponema pallidum 4'-phosphopantetheinyl transferase 0.0023 0.0178 0.0082
Giardia lamblia Hypothetical protein 0.0009 0.0009 0.0013
Schistosoma mansoni retinoblastoma-binding protein 4 (rbbp4) 0.0029 0.0253 0.0253
Echinococcus granulosus transcription initiation factor TFIID subunit 1 0.0009 0.0009 0.0009
Onchocerca volvulus Netrin receptor homolog 0.0029 0.0253 0.0285
Schistosoma mansoni cpg binding protein 0.0085 0.0945 0.0945
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0019 0.0132 0.0128
Trypanosoma cruzi DNA polymerase kappa, putative 0.0179 0.2101 0.2875
Echinococcus granulosus bromodomain containing protein 8 0.0009 0.0009 0.0009
Entamoeba histolytica recQ family helicase, putative 0.0011 0.0031 0.0032
Loa Loa (eye worm) serine/threonine protein phosphatase PP1-beta catalytic subunit 0.0009 0.001 0.001
Trypanosoma cruzi Bromodomain factor 1 0.0009 0.0009 0.0007
Brugia malayi TAZ zinc finger family protein 0.0009 0.0009 0.0009
Trichomonas vaginalis conserved hypothetical protein 0.0019 0.0132 0.0128
Schistosoma mansoni ecdysone-induced protein 78c (dr-78) 0.0016 0.0091 0.0091
Echinococcus multilocularis gcn5proteinral control of amino acid synthesis 0.029 0.3468 0.349
Trichomonas vaginalis conserved hypothetical protein 0.0009 0.0009 0.0005
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.003 0.0267 0.0267
Brugia malayi Voltage-gated calcium channel, L-type, alpha subunit. C. elegans egl-19 ortholog 0.0094 0.1054 0.1054
Mycobacterium tuberculosis Conserved hypothetical protein 0.0125 0.1441 0.1822
Mycobacterium tuberculosis Probable dehydrogenase 0.0582 0.7071 0.8981
Leishmania major peptidyl-prolyl cis-trans isomerase, putative 0.001 0.0017 0.0011
Mycobacterium ulcerans phenolpthiocerol synthesis type-I polyketide synthase PpsC 0.0026 0.0211 0.0203
Brugia malayi PXA domain containing protein 0.0019 0.0126 0.0126
Trichomonas vaginalis bromodomain-containing protein, putative 0.0009 0.0009 0.0005
Mycobacterium ulcerans 6-phosphofructokinase 0.0106 0.1206 0.1199
Schistosoma mansoni ap endonuclease 0.0018 0.0121 0.0121
Echinococcus multilocularis 6 phosphofructokinase 0.0106 0.1206 0.1214
Plasmodium falciparum NAD(P)H-dependent glutamate synthase, putative 0.0023 0.0183 0.0602
Mycobacterium ulcerans dihydrolipoamide dehydrogenase, LpdB 0.0088 0.0984 0.0976
Brugia malayi Nuclear hormone receptor family member nhr-3 0.003 0.0267 0.0267
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0107 0.1217 0.1225
Echinococcus multilocularis protein phosphatase 1 catalytic subunit 0.0009 0.001 0.001
Echinococcus granulosus death domain containing protein 0.0029 0.0253 0.0258
Mycobacterium ulcerans hypothetical protein 0.0316 0.3794 0.3789
Echinococcus granulosus citrate lyase subunit beta protein 0.0049 0.0496 0.0506
Loa Loa (eye worm) acyl carrier protein 0.0011 0.0031 0.0031
Trypanosoma brucei DNA polymerase eta, putative 0.0202 0.2383 0.3261
Schistosoma mansoni myst-related protein 0.0012 0.0041 0.0041
Brugia malayi nuclear hormone receptor family member nhr-6 0.0014 0.007 0.007
Trypanosoma cruzi peptidyl-prolyl cis-trans isomerase 0.001 0.0017 0.0018
Brugia malayi regulator of G-protein signaling rgs-7 0.0019 0.0126 0.0126
Trypanosoma brucei DNA polymerase kappa, putative 0.0179 0.2101 0.2875
Loa Loa (eye worm) AGC/GRK/BARK protein kinase 0.002 0.0138 0.0138
Echinococcus multilocularis dna polymerase eta 0.0202 0.2383 0.2398
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0019 0.0129 0.013
Trichomonas vaginalis bromodomain containing protein, putative 0.0009 0.0009 0.0005
Leishmania major hypothetical protein, conserved 0.0424 0.5124 0.7017
Brugia malayi regulator of G-protein signaling egl-10 0.0019 0.0126 0.0126
Onchocerca volvulus Bile acid receptor homolog 0.003 0.0267 0.0301
Echinococcus multilocularis fetal alzheimer antigen, falz 0.0027 0.0226 0.0227
Plasmodium falciparum flap endonuclease 1 0.0026 0.0218 0.0716
Loa Loa (eye worm) flap endonuclease-1 0.0026 0.0218 0.0218
Loa Loa (eye worm) ImpB/MucB/SamB family protein 0.0125 0.1441 0.1441
Echinococcus granulosus Nuclear hormone receptor HR96 0.0014 0.007 0.0071
Onchocerca volvulus Brd8 homolog 0.0009 0.0009 0.0001
Schistosoma mansoni hypothetical protein 0.0023 0.0183 0.0183
Echinococcus granulosus dihydropyrimidine dehydrogenase NADP 0.0023 0.0183 0.0187
Loa Loa (eye worm) TAR-binding protein 0.0064 0.0682 0.0682
Mycobacterium leprae PHENOLPTHIOCEROL SYNTHESIS TYPE-I POLYKETIDE SYNTHASE PPSD 0.0024 0.0193 0.0234
Trichomonas vaginalis conserved hypothetical protein 0.0009 0.0009 0.0005
Echinococcus granulosus ATPase family AAA domain containing protein 2B 0.0009 0.0009 0.0009
Echinococcus multilocularis dna polymerase kappa 0.0179 0.2101 0.2115
Leishmania major phosphopantetheinyl transferase-like protein 0.0023 0.0178 0.0231
Trichomonas vaginalis conserved hypothetical protein 0.0019 0.0132 0.0128
Mycobacterium ulcerans hypothetical protein 0.0049 0.0496 0.0488
Entamoeba histolytica hypothetical protein 0.0047 0.0468 0.0652
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0088 0.0984 0.1343
Echinococcus granulosus tar DNA binding protein 0.0064 0.0682 0.0696
Loa Loa (eye worm) hypothetical protein 0.0016 0.0091 0.0091
Echinococcus granulosus regulator of G protein signaling 3 0.0019 0.0126 0.0129
Schistosoma mansoni myelin transcription factor 1 myt1 0.0055 0.0569 0.0569
Echinococcus granulosus dihydropyrimidine dehydrogenase NADP 0.0023 0.0183 0.0187
Loa Loa (eye worm) hypothetical protein 0.0014 0.007 0.007
Loa Loa (eye worm) thioredoxin reductase 0.0255 0.304 0.304
Brugia malayi TAR-binding protein 0.0064 0.0682 0.0682
Trichomonas vaginalis conserved hypothetical protein 0.0009 0.0009 0.0005
Trichomonas vaginalis helicase, putative 0.0019 0.0132 0.0128
Trypanosoma cruzi NADH dehydrogenase, putative 0.0023 0.0183 0.0245
Trypanosoma brucei Voltage-dependent calcium channel subunit, putative 0.0057 0.06 0.0817
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0581 0.706 0.7059
Echinococcus multilocularis translational activator gcn1 0.0011 0.0028 0.0028
Trypanosoma cruzi hypothetical protein, conserved 0.0023 0.0183 0.0245
Trypanosoma cruzi ATP-dependent DEAD/H DNA helicase recQ, putative 0.0011 0.0031 0.0037
Mycobacterium leprae DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE 0.0647 0.7872 1
Echinococcus granulosus CREB binding protein 0.0009 0.0009 0.0009
Trypanosoma cruzi peptidyl-prolyl cis-trans isomerase 0.0032 0.029 0.0392
Echinococcus multilocularis L aminoadipate semialdehyde 0.0082 0.0903 0.0909
Echinococcus multilocularis voltage dependent L type calcium channel subunit 0.0094 0.1054 0.1061
Schistosoma mansoni dihydrolipoamide dehydrogenase 0.0088 0.0984 0.0984
Plasmodium vivax histone acetyltransferase GCN5, putative 0.0087 0.0965 0.3153
Schistosoma mansoni terminal deoxycytidyl transferase 0.0125 0.1441 0.1441
Trypanosoma cruzi mitochondrial DNA polymerase beta, putative 0.06 0.7299 1
Echinococcus granulosus FTZ F1 alpha 0.003 0.0267 0.0273
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0047 0.0468 0.0465
Trichomonas vaginalis bromodomain-containing protein, putative 0.0009 0.0009 0.0005
Schistosoma mansoni nuclear receptor 0.0014 0.007 0.007
Trypanosoma brucei AAA ATPase, putative 0.0009 0.0009 0.0007
Mycobacterium ulcerans phosphopantetheinyl transferase, PptII 0.0023 0.0178 0.0169
Entamoeba histolytica hypothetical protein 0.0019 0.0126 0.0166
Schistosoma mansoni protein phosphatase type 1 0.0009 0.001 0.001
Schistosoma mansoni ankyrin 23/unc44 0.0029 0.0253 0.0253
Schistosoma mansoni hypothetical protein 0.0009 0.0009 0.0009
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD2 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0023 0.0182 0.022
Loa Loa (eye worm) DEAH box polypeptide 35 0.0158 0.1846 0.1846
Trichomonas vaginalis bromodomain-containing protein, putative 0.0009 0.0009 0.0005
Echinococcus granulosus bromodomain containing 2 0.0009 0.0009 0.0009
Loa Loa (eye worm) nuclear receptor nhr-7B 0.0014 0.007 0.007
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD3 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0016 0.0097 0.0113
Plasmodium falciparum serine/threonine protein phosphatase PP1 0.0009 0.001 0.0032
Trichomonas vaginalis bsu-protein phosphatase, putative 0.0009 0.001 0.0006
Schistosoma mansoni gcn5proteinral control of amino-acid synthesis 5-like 2 gcnl2 0.029 0.3468 0.3468
Schistosoma mansoni DNA polymerase IV / kappa 0.0039 0.0374 0.0374
Schistosoma mansoni hypothetical protein 0.0016 0.0089 0.0089
Trichomonas vaginalis bromodomain-containing protein, putative 0.0009 0.0009 0.0005
Loa Loa (eye worm) PHD-finger family protein 0.002 0.0143 0.0143
Brugia malayi Nuclear hormone receptor family member nhr-19 0.003 0.0267 0.0267
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.003 0.0267 0.0269
Trichomonas vaginalis conserved hypothetical protein 0.0019 0.0132 0.0128
Brugia malayi AMP-binding enzyme family protein 0.0023 0.0182 0.0182
Echinococcus multilocularis isocitrate dehydrogenase 0.0019 0.0129 0.013
Toxoplasma gondii ImpB/MucB/SamB family protein 0.0039 0.0374 0.123
Trichomonas vaginalis bromodomain-containing protein, putative 0.0009 0.0009 0.0005
Echinococcus granulosus flap endonuclease 1 0.0026 0.0218 0.0222
Mycobacterium ulcerans citrate (pro-3S)-lyase subunit beta 0.0049 0.0496 0.0488
Wolbachia endosymbiont of Brugia malayi dihydrolipoamide dehydrogenase E3 component 0.0088 0.0984 1
Brugia malayi abnormal cell lineage protein 10 (Protein lin-10), putative 0.006 0.0636 0.0636
Trichomonas vaginalis conserved hypothetical protein 0.0009 0.0009 0.0005
Mycobacterium tuberculosis holo-[acyl-carrier protein] synthase AcpS (holo-ACP synthase) (CoA:APO-[ACP]pantetheinephosphotransferase) (CoA:APO-[acyl-carrie 0.0023 0.0178 0.0215
Schistosoma mansoni serine/threonine protein kinase 0.002 0.0138 0.0138
Trichomonas vaginalis phosphofructokinase, putative 0.0029 0.0248 0.0244
Echinococcus multilocularis NADPH:adrenodoxin oxidoreductase 0.0023 0.0183 0.0184
Trypanosoma cruzi importin beta-1 subunit, putative 0.0047 0.0468 0.0637
Loa Loa (eye worm) hypothetical protein 0.0158 0.1846 0.1846
Trichomonas vaginalis DNA helicase recq1, putative 0.0021 0.0151 0.0147
Loa Loa (eye worm) hypothetical protein 0.0009 0.0009 0.0009
Mycobacterium ulcerans long-chain-fatty-acid--CoA ligase 0.0023 0.0182 0.0173
Mycobacterium ulcerans NADH dehydrogenase 0.0023 0.0183 0.0175
Trichomonas vaginalis hypothetical protein 0.0009 0.0009 0.0005
Loa Loa (eye worm) steroid hormone receptor 0.003 0.0267 0.0267
Brugia malayi ImpB/MucB/SamB family protein 0.0125 0.1441 0.1441
Plasmodium vivax importin-beta 2, putative 0.0057 0.0603 0.1958
Trypanosoma cruzi trypanothione reductase, putative 0.0255 0.304 0.4162
Toxoplasma gondii BRCA1 C Terminus (BRCT) domain-containing protein 0.0052 0.0538 0.1768
Loa Loa (eye worm) hypothetical protein 0.0017 0.0107 0.0107
Leishmania major 4-coumarate:coa ligase-like protein 0.0023 0.0182 0.0237
Schistosoma mansoni SET domain protein 0.0012 0.004 0.004
Mycobacterium ulcerans flavoprotein disulfide reductase 0.0088 0.0984 0.0976
Plasmodium falciparum dihydrolipoyl dehydrogenase, apicoplast 0.0088 0.0984 0.3237
Mycobacterium tuberculosis Probable polyketide synthase Pks9 0.0014 0.0064 0.007
Brugia malayi Bromodomain containing protein 0.0009 0.0009 0.0009
Trypanosoma cruzi trypanothione reductase, putative 0.0088 0.0984 0.1343
Echinococcus multilocularis citrate lyase subunit beta protein 0.0049 0.0496 0.0499
Plasmodium vivax thioredoxin reductase, putative 0.0255 0.304 1
Trypanosoma cruzi ISWI complex protein 0.0015 0.0078 0.0102
Schistosoma mansoni hypothetical protein 0.0015 0.0078 0.0078
Echinococcus granulosus dna polymerase kappa 0.0179 0.2101 0.2144
Schistosoma mansoni 6-phosphofructokinase 0.0106 0.1206 0.1206
Trichomonas vaginalis conserved hypothetical protein 0.0009 0.0009 0.0005
Trypanosoma cruzi polo-like protein kinase, putative 0.0283 0.3386 0.4636
Schistosoma mansoni sex comb on midleg homolog 0.0048 0.0487 0.0487
Schistosoma mansoni rotamase 0.0033 0.0299 0.0299
Schistosoma mansoni zinc finger protein 0.0031 0.0277 0.0277
Trypanosoma brucei Bromodomain, putative 0.0009 0.0009 0.0007
Plasmodium falciparum ADP-dependent DNA helicase RecQ 0.0018 0.012 0.0395
Trypanosoma cruzi DNA polymerase kappa, putative 0.0179 0.2101 0.2875
Trichomonas vaginalis conserved hypothetical protein 0.0009 0.0009 0.0005
Loa Loa (eye worm) hypothetical protein 0.0029 0.0253 0.0253
Leishmania major 4-coumarate:coa ligase-like protein 0.0023 0.0182 0.0237
Echinococcus multilocularis histone acetyltransferase MYST2 0.0055 0.0569 0.0573
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD5 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0016 0.0097 0.0113
Loa Loa (eye worm) programmed cell death 8 0.0023 0.0183 0.0183
Trichomonas vaginalis bromodomain-containing protein, putative 0.0009 0.0009 0.0005
Wolbachia endosymbiont of Brugia malayi exonuclease III 0.0018 0.0121 0.1073
Mycobacterium tuberculosis Putative ferredoxin reductase 0.0582 0.7071 0.8981
Trichomonas vaginalis bromodomain-containing protein, putative 0.0009 0.0009 0.0005
Trypanosoma brucei unspecified product 0.0087 0.0961 0.1311
Trypanosoma brucei unspecified product 0.0087 0.0961 0.1311
Giardia lamblia Kinase, putative 0.0009 0.0009 0.0013
Schistosoma mansoni DNA polymerase eta 0.0202 0.2383 0.2383
Leishmania major acetoin dehydrogenase e3 component-like protein 0.0088 0.0984 0.1337
Trypanosoma brucei DNA polymerase kappa, putative 0.0179 0.2101 0.2875
Treponema pallidum fructose-bisphosphate aldolase 0.0581 0.706 1
Trichomonas vaginalis dihydropyrimidine dehydrogenase, putative 0.0023 0.0183 0.0179
Echinococcus granulosus nuclear receptor nhr 48 0.0014 0.007 0.0071
Plasmodium falciparum thioredoxin reductase 0.0088 0.0984 0.3237
Trichomonas vaginalis bromodomain-containing protein, putative 0.0009 0.0009 0.0005
Loa Loa (eye worm) hypothetical protein 0.0014 0.0061 0.0061
Brugia malayi PHD-finger family protein 0.0036 0.0341 0.0341
Mycobacterium ulcerans exodeoxyribonuclease III protein XthA 0.0018 0.0121 0.0112
Mycobacterium tuberculosis Phenolpthiocerol synthesis type-I polyketide synthase PpsC 0.0024 0.0193 0.0234
Brugia malayi F/Y-rich N-terminus family protein 0.0031 0.0278 0.0278
Loa Loa (eye worm) BRM protein 0.0009 0.0009 0.0009
Brugia malayi hypothetical protein 0.0016 0.0091 0.0091
Loa Loa (eye worm) pyridine nucleotide-disufhide oxidoreductase 0.0023 0.0183 0.0183
Schistosoma mansoni myst-related protein 0.0012 0.0041 0.0041
Plasmodium vivax SET domain protein, putative 0.0091 0.1011 0.3306
Loa Loa (eye worm) hypothetical protein 0.0014 0.007 0.007
Trypanosoma brucei GTP-binding nuclear protein rtb2, putative 0.0042 0.0415 0.0564
Trypanosoma cruzi flap endonuclease-1 (FEN-1), putative 0.0026 0.0218 0.0293
Schistosoma mansoni tar DNA-binding protein 0.0064 0.0682 0.0682
Trichomonas vaginalis conserved hypothetical protein 0.0009 0.0009 0.0005
Mycobacterium leprae Probable multifunctional mycocerosic acid synthase membrane associated enzyme Mas 0.0026 0.0211 0.0258
Trypanosoma brucei DNA polymerase kappa, putative 0.01 0.1124 0.1536
Trichomonas vaginalis histone acetyltransferase gcn5, putative 0.001 0.0022 0.0018
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.0042 0.0415 0.0564
Entamoeba histolytica disulphide oxidoreductase, putative 0.0023 0.0183 0.0247
Echinococcus multilocularis axis inhibition protein axin 0.0019 0.0126 0.0127
Toxoplasma gondii bromodomain-containing protein 0.0009 0.0009 0.003
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0091 0.1011 0.1011
Trypanosoma cruzi DNA damage repair protein, putative 0.0039 0.0374 0.0507
Mycobacterium ulcerans NADH dehydrogenase Ndh 0.0023 0.0183 0.0175
Entamoeba histolytica hypothetical protein 0.0012 0.0041 0.0045
Echinococcus granulosus snurportin 1 0.0614 0.7462 0.7613
Echinococcus multilocularis apoptosis inducing factor 1 mitochondrial 0.0023 0.0183 0.0184
Toxoplasma gondii peptidylprolyl isomerase 0.0032 0.029 0.0953
Schistosoma mansoni axis inhibition protein axin 0.0019 0.0126 0.0126
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.003 0.0267 0.0267
Onchocerca volvulus 0.0085 0.0945 0.109
Schistosoma mansoni regulator of G protein signaling 0.0022 0.0159 0.0159
Trichomonas vaginalis conserved hypothetical protein 0.0009 0.0009 0.0005
Mycobacterium ulcerans phenolpthiocerol synthesis type-I polyketide synthase PpsD 0.0024 0.0193 0.0185
Echinococcus granulosus GPCR family 2 0.0016 0.0089 0.0091
Wolbachia endosymbiont of Brugia malayi 4'-phosphopantetheinyl transferase 0.0023 0.0178 0.1661
Loa Loa (eye worm) nucleolar RNA-associated protein alpha 0.0614 0.7462 0.7462
Plasmodium falciparum GTP-binding nuclear protein RAN/TC4 0.0042 0.0415 0.1366
Treponema pallidum diphosphate--fructose-6-phosphate 1-phosphotransferase 0.0029 0.0248 0.0184
Trichomonas vaginalis DNA polymerase IV / kappa, putative 0.0179 0.2101 0.2098
Giardia lamblia Glycerol-3-phosphate dehydrogenase 0.0023 0.0183 0.0259
Trichomonas vaginalis DNA helicase recq, putative 0.0011 0.0031 0.0027
Schistosoma mansoni sulfide quinone reductase 0.0023 0.0183 0.0183
Mycobacterium leprae Probable fructose bisphosphate aldolase Fba 0.0284 0.3394 0.4306
Echinococcus granulosus regulator of G protein signaling 7 0.0019 0.0126 0.0129
Toxoplasma gondii 4'-phosphopantetheinyl transferase superfamily protein 0.0023 0.0178 0.0584
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.003 0.0267 0.0267
Echinococcus granulosus amyloid beta A4 protein 0.0067 0.0723 0.0738
Brugia malayi PXA domain containing protein 0.0019 0.0126 0.0126
Trichomonas vaginalis rotamase, putative 0.0033 0.0299 0.0295
Trichomonas vaginalis glutamate synthase, putative 0.0023 0.0183 0.0179
Echinococcus multilocularis 0.0009 0.0009 0.0009
Brugia malayi polybromodomain protein 0.0009 0.0009 0.0009
Trichomonas vaginalis rotamase, putative 0.0032 0.029 0.0286
Echinococcus granulosus retinoic acid receptor rxr beta a 0.003 0.0267 0.0273
Brugia malayi RNA recognition motif domain containing protein 0.0064 0.0682 0.0682
Loa Loa (eye worm) hypothetical protein 0.0017 0.0109 0.0109
Echinococcus multilocularis dnaJ subfamily B 0.0803 0.9802 0.9865
Toxoplasma gondii 4'-phosphopantetheinyl transferase domain-containing protein 0.0023 0.0178 0.0584
Schistosoma mansoni importin-beta 2 0.0011 0.0028 0.0028
Trypanosoma brucei peptidyl-prolyl cis-trans isomerase, putative 0.001 0.0017 0.0018
Leishmania major DNA polymerase kappa, putative 0.0039 0.0374 0.05
Mycobacterium tuberculosis Probable fructose-bisphosphate aldolase Fba 0.0284 0.3394 0.4306
Toxoplasma gondii PPIC-type PPIASE domain-containing protein 0.001 0.0017 0.0056
Trichomonas vaginalis disulfide oxidoreductase, putative 0.0023 0.0183 0.0179
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0088 0.0984 0.1343
Schistosoma mansoni glutamate synthase 0.0023 0.0183 0.0183
Toxoplasma gondii type I fatty acid synthase, putative 0.0027 0.0223 0.0734
Trichomonas vaginalis conserved hypothetical protein 0.0019 0.0126 0.0122
Trichomonas vaginalis conserved hypothetical protein 0.0019 0.0132 0.0128
Entamoeba histolytica acyl-coA synthetase, putative 0.0023 0.0182 0.0245
Mycobacterium ulcerans hypothetical protein 0.0049 0.0496 0.0488
Echinococcus multilocularis expressed protein 0.0368 0.4427 0.4456
Brugia malayi Pyridine nucleotide-disulphide oxidoreductase family protein 0.0023 0.0183 0.0183
Onchocerca volvulus 0.0009 0.0009 0.0001
Leishmania major 2,4-dihydroxyhept-2-ene-1,7-dioic acid aldolase, putative 0.0049 0.0496 0.0668
Loa Loa (eye worm) hypothetical protein 0.003 0.0267 0.0267
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.003 0.0267 0.0267
Loa Loa (eye worm) hypothetical protein 0.0107 0.1217 0.1217
Chlamydia trachomatis fructose-6-phosphate phosphotransferase 0.0029 0.0248 0.1594
Brugia malayi NADPH:adrenodoxin oxidoreductase, mitochondrial precursor 0.0023 0.0183 0.0183
Schistosoma mansoni serine/threonine protein kinase 0.002 0.0138 0.0138
Leishmania major hypothetical protein, conserved 0.0023 0.0183 0.0239
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0024 0.0195 0.0195
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0019 0.0132 0.0128
Trichomonas vaginalis bromodomain-containing protein 4, brd4, putative 0.0009 0.0009 0.0005
Trichomonas vaginalis CAMK family protein kinase 0.014 0.1622 0.1619
Brugia malayi nuclear receptor NHR-88 0.0014 0.007 0.007
Loa Loa (eye worm) hypothetical protein 0.0057 0.0603 0.0603
Mycobacterium tuberculosis Phenyloxazoline synthase MbtB (phenyloxazoline synthetase) 0.003 0.0258 0.0317
Echinococcus granulosus TNFR CD27 30 40 95 cysteine rich region 0.0045 0.0442 0.0451
Echinococcus multilocularis snurportin 1 0.0614 0.7462 0.751
Brugia malayi Steroid receptor seven-up type 2 0.003 0.0267 0.0267
Schistosoma mansoni RAR-like nuclear receptor 0.003 0.0267 0.0267
Brugia malayi Nuclear hormone receptor family member nhr-1 0.003 0.0267 0.0267
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.003 0.0267 0.0267
Toxoplasma gondii pyruvate dehydrogenase complex subunit PDH-E3II 0.0088 0.0984 0.3237
Mycobacterium ulcerans NADPH:adrenodoxin oxidoreductase FprB 0.0023 0.0183 0.0175
Schistosoma mansoni importin beta-1 0.0057 0.0603 0.0603
Schistosoma mansoni hypothetical protein 0.0205 0.2417 0.2417
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.0581 0.706 1
Trichomonas vaginalis histone acetyltransferase gcn5, putative 0.0009 0.0009 0.0005
Onchocerca volvulus 0.0009 0.0009 0.0001
Echinococcus granulosus SAM and MBT domain containing protein 0.0048 0.0487 0.0497
Schistosoma mansoni protein phosphatase-1 0.0009 0.001 0.001
Brugia malayi Nuclear hormone receptor family member nhr-25 0.003 0.0267 0.0267
Treponema pallidum oxidoreductase 0.0023 0.0183 0.009
Trypanosoma cruzi ATP-dependent 6-phosphofructokinase, glycosomal 0.0106 0.1206 0.1648
Trichomonas vaginalis bromodomain-containing protein, putative 0.0009 0.0009 0.0005
Plasmodium vivax dihydrolipoyl dehydrogenase, mitochondrial, putative 0.0088 0.0984 0.3216
Brugia malayi isocitrate dehydrogenase 0.0019 0.0129 0.0129
Brugia malayi steroid hormone receptor 0.003 0.0267 0.0267
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0107 0.1217 0.1217
Trichomonas vaginalis bromodomain-containing protein, putative 0.0009 0.0009 0.0005
Loa Loa (eye worm) PXA domain-containing protein 0.0019 0.0126 0.0126
Entamoeba histolytica glutamate synthase beta subunit, putative 0.0023 0.0183 0.0247
Trypanosoma brucei hypothetical protein, conserved 0.0023 0.0183 0.0245
Trichomonas vaginalis bromodomain-containing protein, putative 0.0009 0.0009 0.0005
Mycobacterium tuberculosis Polyketide synthase Pks2 0.0024 0.0184 0.0223
Brugia malayi bromodomain containing protein 0.0009 0.0009 0.0009
Schistosoma mansoni nuclear hormone receptor superfamily protein-related 0.0014 0.007 0.007
Trichomonas vaginalis conserved hypothetical protein 0.0009 0.0009 0.0005
Brugia malayi Nuclear hormone receptor family member nhr-25 0.003 0.0267 0.0267
Toxoplasma gondii NADH dehydrogenase (NDH2-II) 0.0023 0.0183 0.0602
Plasmodium vivax acyl-CoA synthetase, putative 0.0017 0.0109 0.0329
Echinococcus granulosus pyridine nucleotide disulfide oxidoreductase 0.0023 0.0183 0.0187
Trypanosoma brucei DNA polymerase beta thumb, putative 0.0084 0.0935 0.1276
Echinococcus multilocularis TNFR CD27 30 40 95 cysteine rich region 0.0045 0.0442 0.0445
Mycobacterium tuberculosis Probable reductase 0.0582 0.7071 0.8981
Plasmodium vivax serine/threonine protein phosphatase PP1, putative 0.0009 0.001 0.0002
Schistosoma mansoni flap endonuclease-1 0.0024 0.0186 0.0186
Plasmodium vivax flap endonuclease 1, putative 0.0026 0.0218 0.0688
Loa Loa (eye worm) hypothetical protein 0.003 0.0267 0.0267
Loa Loa (eye worm) hypothetical protein 0.0009 0.0009 0.0009
Entamoeba histolytica deoxycytidyl transferase, putative 0.0125 0.1441 0.2031
Loa Loa (eye worm) hypothetical protein 0.0014 0.007 0.007
Echinococcus multilocularis geminin 0.0205 0.2417 0.2433
Loa Loa (eye worm) hypothetical protein 0.0019 0.0126 0.0126
Loa Loa (eye worm) hypothetical protein 0.0014 0.007 0.007
Trypanosoma cruzi hypothetical protein, conserved 0.0039 0.0374 0.0507
Plasmodium falciparum isocitrate dehydrogenase [NADP], mitochondrial 0.0019 0.0129 0.0424
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.003 0.0259 0.0264
Leishmania major hypothetical protein, conserved 0.0023 0.0183 0.0239
Entamoeba histolytica thioredoxin reductase, putative 0.0023 0.0183 0.0247
Mycobacterium tuberculosis Probable 6-phosphofructokinase PfkA (phosphohexokinase) (phosphofructokinase) 0.0106 0.1206 0.1524
Brugia malayi nuclear hormone receptor family member odr-7 0.0014 0.007 0.007
Trichomonas vaginalis bromodomain containing protein, putative 0.0009 0.0009 0.0005
Mycobacterium tuberculosis NADPH:adrenodoxin oxidoreductase FprA (NADPH-ferredoxin reductase) 0.0023 0.0183 0.0222
Echinococcus multilocularis polybromo 1 0.0009 0.0009 0.0009
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0581 0.706 0.7059
Schistosoma mansoni ran 0.0042 0.0415 0.0415
Trichomonas vaginalis CAMK family protein kinase 0.014 0.1622 0.1619
Trichomonas vaginalis conserved hypothetical protein 0.0033 0.0299 0.0295
Trichomonas vaginalis bromodomain-containing protein, putative 0.0009 0.0009 0.0005
Trichomonas vaginalis ap endonuclease, putative 0.0018 0.0121 0.0117
Entamoeba histolytica hypothetical protein 0.0023 0.0178 0.0239
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD7 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0016 0.0097 0.0113
Echinococcus granulosus axis inhibition protein axin 0.0019 0.0126 0.0129
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.0035 0.0328 0.0334
Trichomonas vaginalis bromodomain-containing protein, putative 0.0009 0.0009 0.0005
Echinococcus granulosus voltage dependent calcium channel type d subunit|voltage dependent calcium channel|voltage dependent L type calcium channel subu 0.0094 0.1054 0.1076
Schistosoma mansoni hypothetical protein 0.0614 0.7462 0.7462
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0014 0.007 0.0072
Plasmodium falciparum bromodomain protein 2, putative 0.0009 0.0009 0.003
Trichomonas vaginalis glutathione reductase, putative 0.0088 0.0984 0.098
Echinococcus granulosus netrin receptor unc 5 0.0029 0.0253 0.0258
Plasmodium vivax NAD(P)H-dependent glutamate synthase, putative 0.0023 0.0183 0.0574
Echinococcus granulosus GTP binding nuclear protein Ran 0.0042 0.0415 0.0424
Trypanosoma brucei 2,4-dienoyl-coa reductase-like protein 0.0023 0.0183 0.0245
Wolbachia endosymbiont of Brugia malayi dihydrolipoamide dehydrogenase E3 component 0.0088 0.0984 1
Plasmodium falciparum type II NADH:ubiquinone oxidoreductase 0.0023 0.0183 0.0602
Schistosoma mansoni regulator of G protein signaling 17 19 20 (rgs17 19 20) 0.0019 0.0126 0.0126
Trichomonas vaginalis bromodomain-containing protein, putative 0.0009 0.0009 0.0005
Brugia malayi Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain containing protein 0.0065 0.0695 0.0695
Trichomonas vaginalis apoptosis inducing factor, putative 0.0023 0.0183 0.0179
Loa Loa (eye worm) hypothetical protein 0.005 0.0511 0.0511
Mycobacterium ulcerans thioesterase TesA 0.002 0.0143 0.0135
Leishmania major 2-oxoglutarate dehydrogenase, e3 component, lipoamidedehydrogenase-like protein 0.0088 0.0984 0.1337
Entamoeba histolytica hypothetical protein 0.0019 0.0126 0.0166
Echinococcus granulosus nuclear receptor 2DBD gamma 0.003 0.0267 0.0273
Toxoplasma gondii AMP-binding enzyme domain-containing protein 0.0013 0.0057 0.0186
Toxoplasma gondii bromodomain-containing protein 0.0009 0.0009 0.003
Mycobacterium ulcerans hypothetical protein 0.0023 0.0183 0.0175
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0016 0.0091 0.0091
Trypanosoma brucei importin beta-1 subunit, putative 0.0057 0.0603 0.0821
Trypanosoma brucei DNA polymerase IV, putative 0.0179 0.2101 0.2875
Trichomonas vaginalis conserved hypothetical protein 0.0019 0.0126 0.0122
Echinococcus granulosus ankyrin repeat and death domain containing protein 0.0029 0.0253 0.0258
Trichomonas vaginalis conserved hypothetical protein 0.0009 0.0009 0.0005
Brugia malayi Nuclear hormone receptor-like 1 0.003 0.0267 0.0267
Trypanosoma brucei ATP-dependent DEAD/H DNA helicase recQ, putative 0.0011 0.0031 0.0037
Mycobacterium ulcerans long-chain-fatty-acid-CoA ligase 0.0023 0.0182 0.0173
Echinococcus granulosus serine:threonine protein phosphatase PP1 beta 0.0009 0.001 0.001
Plasmodium falciparum zinc finger protein, putative 0.0012 0.0041 0.0134
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0581 0.706 0.7059
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0091 0.1011 0.1018
Brugia malayi Uncoordinated protein 44 0.0029 0.0253 0.0253
Loa Loa (eye worm) hypothetical protein 0.0017 0.0109 0.0109
Echinococcus multilocularis voltage dependent L type calcium channel subunit 0.0094 0.1054 0.1061
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0029 0.0253 0.0253
Trypanosoma cruzi 2,4-dienoyl-coa reductase-like protein, putative 0.0023 0.0183 0.0245
Brugia malayi Regulator of G protein signaling domain containing protein 0.0019 0.0126 0.0126
Trichomonas vaginalis disulfide oxidoreductase, putative 0.0023 0.0183 0.0179
Schistosoma mansoni blooms syndrome DNA helicase 0.0017 0.0097 0.0097
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.007 0.0761 0.0766
Echinococcus multilocularis nuclear receptor subfamily 4 group A 0.0014 0.007 0.007
Schistosoma mansoni serine/threonine protein kinase 0.0283 0.3386 0.3386
Loa Loa (eye worm) hypothetical protein 0.003 0.0267 0.0267
Echinococcus granulosus suppression of tumorigenicity 18 protein 0.0055 0.0569 0.0581
Trichomonas vaginalis bromodomain-containing protein, putative 0.0009 0.0009 0.0005
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.007 0.0761 0.0777
Plasmodium falciparum DNA repair protein REV1, putative 0.0039 0.0374 0.123
Brugia malayi serine/threonine-protein kinase plk-2 0.0283 0.3386 0.3386
Schistosoma mansoni hypothetical protein 0.0016 0.0089 0.0089
Schistosoma mansoni polybromo-1 0.0009 0.0009 0.0009
Schistosoma mansoni high voltage-activated calcium channel Cav1 0.0094 0.1054 0.1054
Schistosoma mansoni serine/threonine protein kinase 0.002 0.0138 0.0138
Loa Loa (eye worm) hypothetical protein 0.0016 0.0091 0.0091
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.003 0.0267 0.0269
Mycobacterium leprae PROBABLE NADPH:ADRENODOXIN OXIDOREDUCTASE FPRB (ADRENODOXIN REDUCTASE) (AR) (FERREDOXIN-NADP(+) REDUCTASE) 0.0023 0.0183 0.0222
Trypanosoma brucei DNA polymerase kappa, putative 0.0179 0.2101 0.2875
Brugia malayi hypothetical protein 0.0065 0.0691 0.0691
Schistosoma mansoni ran 0.0042 0.0415 0.0415
Trichomonas vaginalis bromodomain-containing protein 3, brd3, putative 0.0009 0.0009 0.0005
Onchocerca volvulus 0.0091 0.1011 0.1167
Echinococcus multilocularis importin 5 0.0011 0.0028 0.0028
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD35 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0016 0.0097 0.0113
Loa Loa (eye worm) AMP-binding enzyme family protein 0.003 0.0258 0.0258
Entamoeba histolytica dihydropyrimidine dehydrogenase, putative 0.0023 0.0183 0.0247
Mycobacterium tuberculosis Conserved protein 0.0049 0.0496 0.062
Trichomonas vaginalis bromodomain-containing protein, putative 0.0009 0.0009 0.0005
Loa Loa (eye worm) hypothetical protein 0.0009 0.001 0.001
Mycobacterium ulcerans 4'-phosphopantetheinyl transferase 0.0023 0.0178 0.0169
Plasmodium vivax 6-phosphofructokinase, putative 0.0029 0.0248 0.0789
Trichomonas vaginalis bromodomain-containing protein, putative 0.0009 0.0009 0.0005
Trichomonas vaginalis CAMK family protein kinase 0.0283 0.3386 0.3383
Brugia malayi kap beta 3 protein 0.0011 0.0028 0.0028
Schistosoma mansoni sex comb on midleg homolog 0.0048 0.0487 0.0487
Schistosoma mansoni methyl-cpg binding protein mbd 0.0017 0.01 0.01
Loa Loa (eye worm) hypothetical protein 0.0029 0.0253 0.0253
Schistosoma mansoni bromodomain containing 0.0009 0.0009 0.0009
Brugia malayi hypothetical protein 0.0019 0.0126 0.0126
Schistosoma mansoni glutaminase 0.0819 1 1
Plasmodium vivax DNA repair protein REV1, putative 0.0039 0.0374 0.1203
Treponema pallidum thioredoxin reductase (trxB) 0.0023 0.0183 0.009
Entamoeba histolytica Flap nuclease, putative 0.0026 0.0218 0.0296
Brugia malayi polybromodomain protein 0.0009 0.0009 0.0009
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.003 0.0259 0.0261
Brugia malayi 6-phosphofructokinase 0.0106 0.1206 0.1206
Trichomonas vaginalis histone acetyltransferase gcn5, putative 0.0009 0.0009 0.0005
Trichomonas vaginalis bromodomain-containing protein, putative 0.0009 0.0009 0.0005
Trichomonas vaginalis bromodomain-containing protein, putative 0.0009 0.0009 0.0005
Trichomonas vaginalis CAMK family protein kinase 0.0283 0.3386 0.3383
Trypanosoma cruzi DNA polymerase beta thumb, putative 0.0084 0.0935 0.1276
Loa Loa (eye worm) hypothetical protein 0.003 0.0267 0.0267
Echinococcus multilocularis Bromodomain containing protein 0.0009 0.0009 0.0009
Loa Loa (eye worm) hypothetical protein 0.0034 0.0316 0.0316
Trypanosoma cruzi DNA polymerase kappa, putative 0.0179 0.2101 0.2875
Trypanosoma brucei bromodomain factor 2 protein, putative 0.0009 0.0009 0.0007
Echinococcus multilocularis thioredoxin glutathione reductase 0.0257 0.3059 0.3079
Trichomonas vaginalis disulfide oxidoreductase, putative 0.0023 0.0183 0.0179
Brugia malayi Bromodomain containing protein 0.0085 0.0946 0.0946
Giardia lamblia DNA damage repair protein 0.0039 0.0374 0.053
Loa Loa (eye worm) RGS-3 protein 0.0019 0.0126 0.0126
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.0018 0.0121 0.016
Trypanosoma brucei DNA polymerase kappa, putative 0.0092 0.1034 0.1412
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0019 0.0132 0.0128
Mycobacterium tuberculosis Probable multifunctional mycocerosic acid synthase membrane-associated Mas 0.0026 0.0211 0.0258
Echinococcus multilocularis voltage dependent calcium channel 0.0094 0.1054 0.1061
Trichomonas vaginalis phosphofructokinase, putative 0.0029 0.0248 0.0244
Echinococcus granulosus geminin 0.0205 0.2417 0.2466
Mycobacterium leprae PHENOLPTHIOCEROL SYNTHESIS TYPE-I POLYKETIDE SYNTHASE PPSA 0.0024 0.0193 0.0234
Loa Loa (eye worm) 6-phosphofructokinase 0.0106 0.1206 0.1206
Loa Loa (eye worm) CXXC zinc finger family protein 0.0085 0.0945 0.0945
Toxoplasma gondii HEAT repeat-containing protein 0.0011 0.0028 0.0091
Loa Loa (eye worm) hypothetical protein 0.0082 0.0903 0.0903
Trypanosoma cruzi pyridine nucleotide-disulphide oxidoreductase, putative 0.0023 0.0183 0.0245
Echinococcus granulosus voltage dependent calcium channel 0.0094 0.1054 0.1076
Loa Loa (eye worm) hypothetical protein 0.0009 0.0009 0.0009
Trypanosoma brucei pyridine nucleotide-disulphide oxidoreductase, putative 0.0023 0.0183 0.0245
Trichomonas vaginalis bromodomain-containing protein, putative 0.0009 0.0009 0.0005
Toxoplasma gondii phosphofructokinase PFKII 0.0029 0.0248 0.0817
Trichomonas vaginalis set domain proteins, putative 0.0706 0.8602 0.8601
Mycobacterium ulcerans NADH dehydrogenase Ndh1 0.0023 0.0183 0.0175
Loa Loa (eye worm) GTP-binding nuclear protein RAN/TC4 0.0042 0.0415 0.0415
Echinococcus multilocularis regulator of G protein signaling 7 0.0019 0.0126 0.0127
Mycobacterium ulcerans NADPH dependent 2,4-dienoyl-CoA reductase FadH 0.0023 0.0183 0.0175
Brugia malayi Bloom's syndrome protein homolog 0.0021 0.0151 0.0151
Trichomonas vaginalis phosphofructokinase, putative 0.0029 0.0248 0.0244
Brugia malayi A-kinase anchor protein 10, precursor 0.0019 0.0126 0.0126
Schistosoma mansoni retinoic acid receptor RXR 0.003 0.0267 0.0267
Brugia malayi phosphofructokinase 0.0106 0.1206 0.1206
Trypanosoma brucei ATP-dependent 6-phosphofructokinase, glycosomal 0.0106 0.1206 0.1648
Schistosoma mansoni thyroid hormone receptor 0.003 0.0267 0.0267
Trichomonas vaginalis conserved hypothetical protein 0.0009 0.0009 0.0005
Loa Loa (eye worm) hypothetical protein 0.0014 0.007 0.007
Brugia malayi aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase 0.0082 0.0903 0.0903
Echinococcus granulosus 6 phosphofructokinase 0.0106 0.1206 0.1231
Loa Loa (eye worm) hypothetical protein 0.0017 0.0099 0.0099
Schistosoma mansoni CREB-binding protein 2 0.0009 0.0009 0.0009
Trichomonas vaginalis conserved hypothetical protein 0.0009 0.0009 0.0005
Echinococcus granulosus Regulator of G protein signaling 20 0.0019 0.0126 0.0129
Leishmania major mitochondrial DNA polymerase beta-PAK, putative 0.0284 0.3398 0.4649
Trypanosoma cruzi DNA polymerase kappa, putative 0.0179 0.2101 0.2875
Toxoplasma gondii pyridine nucleotide-disulfide oxidoreductase domain-containing protein 0.0023 0.0183 0.0602
Entamoeba histolytica acyl-CoA synthetase, putative 0.0026 0.0212 0.0287
Loa Loa (eye worm) hypothetical protein 0.0092 0.1034 0.1034
Trypanosoma brucei DNA damage repair protein, putative 0.0039 0.0374 0.0507
Trypanosoma cruzi DNA polymerase eta, putative 0.0115 0.1316 0.1798
Mycobacterium tuberculosis Polyketide synthase Pks13 0.0036 0.0341 0.0423
Trypanosoma cruzi apurinic/apyrimidinic endonuclease 0.0018 0.0121 0.016
Plasmodium vivax glutathione reductase, putative 0.0255 0.304 1
Echinococcus granulosus expressed protein 0.0368 0.4427 0.4517
Mycobacterium tuberculosis Probable thioesterase TesA 0.002 0.0143 0.0171
Echinococcus multilocularis atpase aaa+ type core atpase aaa type core 0.0814 0.9936 1
Entamoeba histolytica serine/threonine protein kinase, putative 0.0283 0.3386 0.4789
Trichomonas vaginalis histone acetyltransferase gcn5, putative 0.0009 0.0009 0.0005
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0103 0.1163 0.1588
Loa Loa (eye worm) phosphofructokinase 0.0106 0.1206 0.1206
Trichomonas vaginalis conserved hypothetical protein 0.0009 0.0009 0.0005
Entamoeba histolytica acyl-CoA synthetase, putative 0.0023 0.0182 0.0245
Mycobacterium tuberculosis NAD(P)H quinone reductase LpdA 0.0647 0.7872 1
Leishmania major isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0019 0.0129 0.0164
Leishmania major peptidyl-prolyl cis-trans isomerase/rotamase, putative,PPIase, putative 0.0032 0.029 0.0385
Onchocerca volvulus 0.0706 0.8602 1
Schistosoma mansoni hypothetical protein 0.002 0.0143 0.0143
Schistosoma mansoni ap endonuclease 0.0018 0.0121 0.0121
Leishmania major DNA polymerase eta, putative 0.0115 0.1316 0.1792
Entamoeba histolytica pyridine nucleotide-disulfide oxidoreductase family protein 0.0023 0.0183 0.0247
Trichomonas vaginalis CAMK family protein kinase 0.0283 0.3386 0.3383
Trypanosoma brucei Bromodomain, putative 0.0009 0.0009 0.0007
Onchocerca volvulus Bromodomain adjacent to zinc finger domain protein 1A homolog 0.0009 0.0009 0.0001
Brugia malayi AMP-binding enzyme family protein 0.003 0.0258 0.0258
Echinococcus multilocularis terminal deoxycytidyl transferase rev1 0.0125 0.1441 0.145
Loa Loa (eye worm) RNA recognition domain-containing protein domain-containing protein 0.0064 0.0682 0.0682
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0088 0.0984 0.1343
Mycobacterium ulcerans glutamate synthase subunit beta 0.0023 0.0183 0.0175
Brugia malayi Nuclear hormone receptor-like 1 0.0016 0.0091 0.0091
Brugia malayi hypothetical protein 0.0014 0.007 0.007
Echinococcus multilocularis ankyrin repeat and death domain containing protein 0.0029 0.0253 0.0255
Entamoeba histolytica Ran family GTPase 0.0042 0.0415 0.0576
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0088 0.0984 0.1343
Schistosoma mansoni hypothetical protein 0.0029 0.0253 0.0253
Echinococcus granulosus voltage dependent L type calcium channel subunit|voltage dependent calcium channel 0.0094 0.1054 0.1076
Brugia malayi glutaminase DH11.1 0.0819 1 1
Onchocerca volvulus 0.0082 0.0903 0.1042
Echinococcus granulosus apoptosis inducing factor 1 mitochondrial 0.0023 0.0183 0.0187
Trypanosoma brucei unspecified product 0.0166 0.1937 0.265
Echinococcus granulosus NADPH:adrenodoxin oxidoreductase 0.0023 0.0183 0.0187
Schistosoma mansoni tar DNA-binding protein 0.0064 0.0682 0.0682
Loa Loa (eye worm) hypothetical protein 0.0055 0.0569 0.0569
Schistosoma mansoni axis inhibition protein axin 0.0019 0.0126 0.0126
Loa Loa (eye worm) hypothetical protein 0.0017 0.0109 0.0109
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0019 0.0132 0.0128
Mycobacterium tuberculosis Probable NADPH dependent 2,4-dienoyl-CoA reductase FadH (2,4-dienoyl coenzyme A reductase) (4-enoyl-CoA reductase) 0.0023 0.0183 0.0222
Trichomonas vaginalis bromodomain-containing protein, putative 0.0009 0.0009 0.0005
Entamoeba histolytica acetyltransferase, GNAT family 0.0077 0.0849 0.1192
Trypanosoma brucei DNA polymerase kappa, putative 0.0179 0.2101 0.2875
Brugia malayi ImpB/MucB/SamB family protein 0.0202 0.2383 0.2383
Plasmodium falciparum ferrodoxin reductase-like protein 0.0023 0.0183 0.0602
Echinococcus multilocularis tumor necrosis factor receptor superfamily 0.0045 0.0442 0.0445
Echinococcus granulosus serine:threonine protein kinase PLK1 0.0283 0.3386 0.3454
Trichomonas vaginalis conserved hypothetical protein 0.0009 0.0009 0.0005
Leishmania major 2,4-dienoyl-coa reductase-like protein 0.0023 0.0183 0.0239
Mycobacterium ulcerans DNA polymerase IV 0.0179 0.2101 0.2094
Trichomonas vaginalis bromodomain-containing protein, putative 0.0009 0.0009 0.0005
Mycobacterium ulcerans polyketide synthase Pks9 0.0016 0.0091 0.0083
Schistosoma mansoni zinc finger protein 0.0015 0.0078 0.0078
Echinococcus granulosus expressed protein 0.0033 0.0299 0.0305
Brugia malayi Nuclear hormone receptor family member nhr-31 0.003 0.0267 0.0267
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.0581 0.706 1
Schistosoma mansoni nuclear hormone receptor 0.0014 0.007 0.007
Leishmania major hypothetical protein, conserved 0.0011 0.0028 0.0026
Brugia malayi Death domain containing protein 0.0029 0.0253 0.0253
Leishmania major 2,4-dienoyl-coa reductase fadh1, putative 0.0023 0.0183 0.0239
Schistosoma mansoni nuclear hormone receptor 0.003 0.0267 0.0267
Brugia malayi Nuclear hormone receptor family member nhr-40 0.003 0.0267 0.0267
Mycobacterium tuberculosis Probable membrane NADH dehydrogenase NdhA 0.0582 0.7071 0.8981
Treponema pallidum diphosphate--fructose-6-phosphate 1-phosphotransferase 0.0106 0.1206 0.1565
Brugia malayi Bromodomain containing protein 0.0009 0.0009 0.0009
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.003 0.0267 0.0269
Echinococcus multilocularis global transcription activator snf2l2 0.0009 0.0009 0.0009
Toxoplasma gondii phosphofructokinase domain-containing protein 0.0029 0.0248 0.0817
Trichomonas vaginalis phosphofructokinase, putative 0.0106 0.1206 0.1203
Trichomonas vaginalis bromodomain-containing protein, putative 0.0009 0.0009 0.0005
Echinococcus multilocularis voltage dependent calcium channel type d subunit 0.0094 0.1054 0.1061
Loa Loa (eye worm) voltage-dependent calcium channel 0.002 0.0137 0.0137
Echinococcus granulosus tumor necrosis factor receptor superfamily 0.0045 0.0442 0.0451
Toxoplasma gondii flap structure-specific endonuclease 1, putative 0.0026 0.0218 0.0716
Giardia lamblia Pyrophosphate-fructose 6-phosphate 1-phosphotransferase alpha subunit 0.0029 0.0248 0.0352
Trichomonas vaginalis bromodomain-containing protein, putative 0.0009 0.0009 0.0005
Trichomonas vaginalis conserved hypothetical protein 0.0019 0.0126 0.0122
Schistosoma mansoni regulator of G protein signaling 0.0019 0.0126 0.0126
Mycobacterium tuberculosis Probable polyketide synthase Pks5 0.0024 0.0184 0.0223
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.003 0.0267 0.0267
Toxoplasma gondii hypothetical protein 0.0017 0.0107 0.0353
Echinococcus multilocularis nuclear receptor nhr 48 0.0014 0.007 0.007
Trypanosoma brucei DNA polymerase IV, putative 0.0179 0.2101 0.2875
Leishmania major serine/threonine protein phosphatase catalytic subunit, putative 0.0009 0.001 0.0001
Schistosoma mansoni transcription initiation factor tfiid 0.0009 0.0009 0.0009
Trypanosoma cruzi Bromodomain, putative 0.0009 0.0009 0.0007
Schistosoma mansoni hypothetical protein 0.0016 0.0089 0.0089
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD7 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0023 0.0182 0.022
Mycobacterium leprae conserved hypothetical protein 0.0023 0.0178 0.0215
Loa Loa (eye worm) MBCTL1 0.0055 0.0569 0.0569
Loa Loa (eye worm) nuclear hormone receptor-like 1 0.0016 0.0091 0.0091
Trichomonas vaginalis cat eye syndrome critical region protein 2, cscr2, putative 0.0087 0.0965 0.0961
Toxoplasma gondii bromodomain-containing protein 0.0009 0.0009 0.003
Echinococcus multilocularis mixed lineage leukemia protein mll 0.0024 0.0195 0.0196
Mycobacterium tuberculosis Probable chain -fatty-acid-CoA ligase FadD13 (fatty-acyl-CoA synthetase) 0.0023 0.0182 0.022
Toxoplasma gondii histone lysine methyltransferase SET1 0.0174 0.2041 0.6714
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0014 0.007 0.007
Mycobacterium tuberculosis Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras 0.0647 0.7872 1
Brugia malayi Nuclear hormone receptor family member nhr-41 0.003 0.0267 0.0267
Loa Loa (eye worm) mbt repeat family protein 0.0048 0.0487 0.0487
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0084 0.0935 0.1276
Trypanosoma cruzi hypothetical protein, conserved 0.0424 0.5124 0.7019
Onchocerca volvulus 0.0009 0.0009 0.0001
Trichomonas vaginalis conserved hypothetical protein 0.0009 0.0009 0.0005
Trichomonas vaginalis bromodomain and PHD finger-containing protein, putative 0.0009 0.0009 0.0005
Loa Loa (eye worm) hypothetical protein 0.0094 0.1054 0.1054
Schistosoma mansoni bromodomain containing protein 0.0009 0.0009 0.0009
Trichomonas vaginalis bromodomain containing protein, putative 0.0009 0.0009 0.0005
Mycobacterium ulcerans Type I modular polyketide synthase 0.0024 0.0193 0.0185
Loa Loa (eye worm) hypothetical protein 0.0014 0.007 0.007
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0024 0.0195 0.0196
Toxoplasma gondii histone lysine acetyltransferase GCN5-B 0.0087 0.0965 0.3174
Echinococcus granulosus peregrin 0.0009 0.0009 0.0009
Giardia lamblia DINP protein human, muc B family 0.0139 0.1605 0.2273
Trichomonas vaginalis conserved hypothetical protein 0.0019 0.0126 0.0122
Loa Loa (eye worm) fatty acid synthase 0.0024 0.0189 0.0189
Trypanosoma cruzi serine/threonine protein phosphatase catalytic subunit, putative 0.0009 0.001 0.0008
Echinococcus granulosus nuclear receptor subfamily 1 group D 0.0016 0.0091 0.0093
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.003 0.0267 0.0273
Plasmodium falciparum importin beta, putative 0.0057 0.0603 0.1982
Echinococcus multilocularis CREB binding protein 0.0009 0.0009 0.0009
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0085 0.0948 0.0967
Echinococcus granulosus protein phosphatase 1, catalytic subunit, beta isozyme 0.0009 0.001 0.001
Trichomonas vaginalis CAMK family protein kinase 0.0283 0.3386 0.3383
Trichomonas vaginalis importin beta-1, putative 0.0047 0.0468 0.0465
Trypanosoma cruzi hypothetical protein, conserved 0.0023 0.0183 0.0245
Echinococcus granulosus global transcription activator snf2l2 0.0009 0.0009 0.0009
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0014 0.007 0.007
Echinococcus granulosus fetal alzheimer antigen falz 0.0027 0.0226 0.023
Treponema pallidum NADH oxidase 0.0088 0.0984 0.1244
Loa Loa (eye worm) histone methyltransferase 0.003 0.0259 0.0259
Loa Loa (eye worm) hypothetical protein 0.0016 0.0089 0.0089
Trichomonas vaginalis conserved hypothetical protein 0.0009 0.0009 0.0005
Loa Loa (eye worm) RNA binding protein 0.0064 0.0682 0.0682
Trypanosoma cruzi hypothetical protein, conserved 0.0009 0.0009 0.0007
Trypanosoma brucei protein phosphatase 1, putative 0.0009 0.001 0.0008
Mycobacterium ulcerans Type I modular polyketide synthase 0.0024 0.0193 0.0185
Echinococcus multilocularis serine:threonine protein phosphatase PP1 beta 0.0009 0.001 0.001
Trypanosoma cruzi Voltage-dependent calcium channel subunit, putative 0.0057 0.06 0.0817
Onchocerca volvulus 0.0049 0.0499 0.0571
Loa Loa (eye worm) hypothetical protein 0.0014 0.007 0.007
Trypanosoma brucei dihydrolipoamide dehydrogenase, point mutation 0.0088 0.0984 0.1343
Echinococcus granulosus mixed lineage leukemia protein mll 0.0024 0.0195 0.0199
Brugia malayi RNA binding protein 0.0064 0.0682 0.0682
Plasmodium falciparum thioredoxin reductase 0.0255 0.304 1
Mycobacterium ulcerans dehydrogenase 0.0023 0.0183 0.0175
Schistosoma mansoni cpg binding protein 0.0092 0.1028 0.1028
Trypanosoma brucei hypothetical protein, conserved 0.0039 0.0374 0.0507
Mycobacterium leprae PHENOLPTHIOCEROL SYNTHESIS TYPE-I POLYKETIDE SYNTHASE PPSB 0.002 0.0134 0.016
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0581 0.706 0.7059
Mycobacterium ulcerans fructose-bisphosphate aldolase 0.0284 0.3394 0.3389
Echinococcus multilocularis bromodomain containing 2 0.0009 0.0009 0.0009
Trichomonas vaginalis mercuric reductase, putative 0.0088 0.0984 0.098
Trichomonas vaginalis hypothetical protein 0.001 0.0021 0.0017
Echinococcus multilocularis isocitrate dehydrogenase 2 (NADP+) 0.0019 0.0129 0.013
Schistosoma mansoni regulator of G protein signaling 0.0019 0.0126 0.0126
Giardia lamblia NADH oxidase lateral transfer candidate 0.0088 0.0984 0.1394
Chlamydia trachomatis thioredoxin reductase 0.0023 0.0183 0.0849
Onchocerca volvulus Serine\/threonine kinase homolog 0.0283 0.3386 0.393
Mycobacterium tuberculosis Probable thioredoxin reductase TrxB2 (TRXR) (TR) 0.0023 0.0183 0.0222
Trypanosoma cruzi bromodomain factor 2 protein 0.0009 0.0009 0.0007
Mycobacterium ulcerans citrate lyase beta subunit, CitE_2 0.0049 0.0496 0.0488
Brugia malayi acetyltransferase, GNAT family protein 0.029 0.3468 0.3468
Trichomonas vaginalis conserved hypothetical protein 0.0009 0.0009 0.0005
Brugia malayi CXXC zinc finger family protein 0.0085 0.0945 0.0945
Brugia malayi hypothetical protein 0.0014 0.007 0.007
Echinococcus multilocularis flap endonuclease 1 0.0026 0.0218 0.0219
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.003 0.0267 0.0301
Mycobacterium leprae THIOREDOXIN TRXC (TRX) (MPT46) 0.0023 0.0183 0.0222
Chlamydia trachomatis fructose-6-phosphate phosphotransferase 0.0029 0.0248 0.1594
Echinococcus granulosus translational activator gcn1 0.0011 0.0028 0.0028
Brugia malayi Probable G protein-coupled receptor kinase F19C6.1, putative 0.002 0.0138 0.0138
Leishmania major flap endonuclease-1 (FEN-1), putative 0.0026 0.0218 0.0286
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.003 0.0267 0.0267
Trichomonas vaginalis conserved hypothetical protein 0.0009 0.0009 0.0005
Echinococcus multilocularis serine:threonine protein phosphatase PP1 isozyme 0.0009 0.001 0.001
Echinococcus granulosus sulfide:quinone oxidoreductase 0.0023 0.0183 0.0187
Trichomonas vaginalis conserved hypothetical protein 0.0009 0.0009 0.0005
Chlamydia trachomatis dihydrolipoyl dehydrogenase 0.0088 0.0984 1
Schistosoma mansoni z-protein (S1r protein) 0.0019 0.0126 0.0126
Brugia malayi Bromodomain containing protein 0.0045 0.0443 0.0443
Echinococcus granulosus cpg binding protein 0.0092 0.1028 0.1049
Echinococcus multilocularis ATPase family AAA domain containing protein 2B 0.0009 0.0009 0.0009
Loa Loa (eye worm) X11 protein 0.0067 0.0723 0.0723
Loa Loa (eye worm) DR-78 0.0014 0.007 0.007
Schistosoma mansoni netrin receptor unc5 0.0029 0.0253 0.0253
Mycobacterium ulcerans glutaminase 0.0819 1 1
Mycobacterium ulcerans polyketide synthase 0.0024 0.0193 0.0185
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0581 0.706 0.7059
Mycobacterium ulcerans thioesterase 0.002 0.0143 0.0135
Trichomonas vaginalis protein phosphatase-1, putative 0.0009 0.001 0.0006
Echinococcus multilocularis dihydropyrimidine dehydrogenase (NADP+) 0.0023 0.0183 0.0184
Trypanosoma brucei isocitrate dehydrogenase, putative 0.0019 0.0129 0.0171
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0014 0.007 0.0071
Entamoeba histolytica ankyrin repeat protein, putative 0.0009 0.0009 0.000000065019
Trichomonas vaginalis bromodomain-containing protein, putative 0.0009 0.0009 0.0005
Echinococcus multilocularis suppression of tumorigenicity 18 protein 0.0055 0.0569 0.0573
Schistosoma mansoni cpg binding protein 0.0092 0.1028 0.1028
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0019 0.0129 0.013
Onchocerca volvulus Protein ultraspiracle homolog 0.003 0.0267 0.0301
Brugia malayi AMP-binding enzyme family protein 0.0023 0.0182 0.0182
Echinococcus granulosus Bromodomain containing protein 0.0009 0.0009 0.0009
Trypanosoma brucei hypothetical protein, conserved 0.0023 0.0178 0.0238
Leishmania major DNA polymerase kappa, putative 0.0139 0.1605 0.2189
Trypanosoma cruzi 2,4-dihydroxyhept-2-ene-1,7-dioic acid aldolase, putative 0.0049 0.0496 0.0674
Plasmodium vivax 6-phosphofructokinase, putative 0.0029 0.0248 0.0789
Trypanosoma cruzi mitochondrial DNA polymerase beta, putative 0.06 0.7299 1
Toxoplasma gondii hypothetical protein 0.0097 0.1088 0.3579
Mycobacterium tuberculosis Probable membrane bound polyketide synthase Pks6 0.0036 0.0341 0.0423
Echinococcus granulosus NADP dependent isocitrate dehydrogenase 0.0019 0.0129 0.0132
Mycobacterium ulcerans thioredoxin reductase TrxB2 0.0023 0.0183 0.0175
Mycobacterium ulcerans monoxygenase 0.0023 0.0183 0.0175
Trichomonas vaginalis conserved hypothetical protein 0.0009 0.0009 0.0005
Mycobacterium tuberculosis Probable soluble pyridine nucleotide transhydrogenase SthA (STH) (NAD(P)(+) transhydrogenase [B-specific]) (nicotinamide nucleot 0.0088 0.0984 0.1241
Trichomonas vaginalis conserved hypothetical protein 0.0009 0.0009 0.0005
Trypanosoma brucei hypothetical protein, conserved 0.0039 0.0374 0.0507
Echinococcus granulosus CREB binding protein 0.0009 0.0009 0.0009
Trichomonas vaginalis flap endonuclease-1, putative 0.0026 0.0218 0.0214
Trichomonas vaginalis bromodomain-containing protein, putative 0.0009 0.0009 0.0005
Echinococcus multilocularis serine:threonine protein phosphatase PP1 gamma 0.0009 0.001 0.001
Plasmodium falciparum dihydrolipoyl dehydrogenase, mitochondrial 0.0088 0.0984 0.3237
Trichomonas vaginalis bromodomain containing protein, putative 0.0009 0.0009 0.0005
Trichomonas vaginalis conserved hypothetical protein 0.0009 0.0009 0.0005
Echinococcus multilocularis dihydrolipoamide dehydrogenase 0.0088 0.0984 0.099
Trichomonas vaginalis conserved hypothetical protein 0.0009 0.0009 0.0005
Giardia lamblia Glutamate synthase 0.0023 0.0183 0.0259
Trichomonas vaginalis conserved hypothetical protein 0.0009 0.0009 0.0005
Loa Loa (eye worm) hypothetical protein 0.0014 0.007 0.007
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.0018 0.0121 0.0123
Brugia malayi nuclear receptor subfamily 1, group D, member 1, putative 0.0014 0.007 0.007
Trypanosoma brucei Bromodomain, putative 0.0009 0.0009 0.0007
Echinococcus granulosus thyroid hormone receptor alpha 0.0014 0.007 0.0071
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.0035 0.0328 0.033
Trypanosoma brucei DNA polymerase kappa, putative 0.0179 0.2101 0.2875
Trichomonas vaginalis bromodomain-containing protein, putative 0.0009 0.0009 0.0005
Mycobacterium ulcerans phenolpthiocerol synthesis type-I polyketide synthase PpsE 0.0016 0.0091 0.0083
Schistosoma mansoni regulator of G protein signaling 0.0019 0.0126 0.0126
Loa Loa (eye worm) importin-beta domain-containing protein 0.0011 0.0028 0.0028
Echinococcus multilocularis sulfide:quinone oxidoreductase 0.0023 0.0183 0.0184
Schistosoma mansoni acetyl-CoA C-acetyltransferase 0.0027 0.0226 0.0226
Trichomonas vaginalis conserved hypothetical protein 0.0019 0.0132 0.0128
Echinococcus granulosus L aminoadipate semialdehyde 0.0082 0.0903 0.0922
Mycobacterium tuberculosis Probable NADPH:adrenodoxin oxidoreductase FprB (adrenodoxin reductase) (AR) (ferredoxin-NADP(+) reductase) 0.0023 0.0183 0.0222
Echinococcus granulosus regulator of G protein signaling 3 0.0019 0.0126 0.0129
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0088 0.0984 0.1343
Trichomonas vaginalis bromodomain-containing protein, putative 0.0009 0.0009 0.0005
Mycobacterium tuberculosis Probable polyketide synthase Pks7 0.0026 0.0211 0.0258
Loa Loa (eye worm) hypothetical protein 0.0023 0.0182 0.0182
Loa Loa (eye worm) hypothetical protein 0.0069 0.0748 0.0748
Trichomonas vaginalis conserved hypothetical protein 0.0009 0.0009 0.0005
Brugia malayi photoreceptor-specific nuclear receptor 0.003 0.0267 0.0267
Trichomonas vaginalis bromodomain-containing protein, putative 0.0009 0.0009 0.0005
Brugia malayi Pyridine nucleotide-disulphide oxidoreductase family protein 0.0023 0.0183 0.0183
Trichomonas vaginalis bromodomain-containing protein, putative 0.0009 0.0009 0.0005
Trypanosoma brucei ISWI complex protein 0.0015 0.0078 0.0102
Brugia malayi ecdysone receptor 0.0014 0.007 0.007
Mycobacterium ulcerans DNA polymerase IV 0.0179 0.2101 0.2094
Leishmania major DNA damage repair protein, putative 0.0039 0.0374 0.05
Loa Loa (eye worm) nuclear hormone receptor 0.0014 0.007 0.007
Loa Loa (eye worm) hypothetical protein 0.0009 0.0009 0.0009
Leishmania major DNA polymerase eta, putative 0.0202 0.2383 0.3256
Trypanosoma brucei ULK family serine/threonine-protein kinase, putative 0.0012 0.0039 0.0048
Brugia malayi Nuclear hormone receptor family member nhr-49 0.003 0.0267 0.0267
Trichomonas vaginalis phosphofructokinase, putative 0.0029 0.0248 0.0244
Mycobacterium ulcerans multifunctional mycocerosic acid synthase membrane-associated Mas 0.0026 0.0211 0.0203
Schistosoma mansoni NADP-specific isocitrate dehydrogenase 0.0019 0.0129 0.0129
Echinococcus multilocularis bloom syndrome protein 0.0021 0.0151 0.0152
Echinococcus granulosus polybromo 1 0.0009 0.0009 0.0009
Echinococcus granulosus importin subunit beta 1 0.0057 0.0603 0.0615
Trypanosoma brucei dihydrolipoyl dehydrogenase 0.0088 0.0984 0.1343
Trichomonas vaginalis bromodomain-containing protein, putative 0.0009 0.0009 0.0005
Echinococcus granulosus histone acetyltransferase MYST2 0.0055 0.0569 0.0581
Echinococcus multilocularis amyloid beta A4 protein 0.0067 0.0723 0.0728
Echinococcus granulosus A kinase anchor protein 10 mitochondrial 0.0019 0.0126 0.0129
Loa Loa (eye worm) hypothetical protein 0.0023 0.0182 0.0182
Echinococcus multilocularis PH interacting protein 0.0009 0.0009 0.0009
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0088 0.0984 0.1337
Echinococcus multilocularis nuclear receptor subfamily 1 group D 0.0016 0.0091 0.0092
Brugia malayi hypothetical protein 0.0019 0.0126 0.0126
Loa Loa (eye worm) kap beta 3 protein 0.0011 0.0028 0.0028
Loa Loa (eye worm) hypothetical protein 0.0017 0.0109 0.0109
Trichomonas vaginalis phosphofructokinase, putative 0.0106 0.1206 0.1203
Schistosoma mansoni Tr4/Tr2 (homologue) 0.003 0.0267 0.0267
Echinococcus granulosus voltage dependent calcium channel type d subunit|voltage dependent calcium channel alpha 1 0.0094 0.1054 0.1076
Loa Loa (eye worm) hypothetical protein 0.0017 0.0109 0.0109
Loa Loa (eye worm) hypothetical protein 0.0042 0.0408 0.0408
Mycobacterium ulcerans phenolpthiocerol synthesis type-I polyketide synthase PpsB 0.002 0.0134 0.0126
Echinococcus multilocularis Ankyrin 0.0029 0.0253 0.0255
Loa Loa (eye worm) G protein signaling regulator EGL-10 0.0019 0.0126 0.0126
Plasmodium vivax isocitrate dehydrogenase [NADP], mitochondrial, putative 0.0019 0.0129 0.0395
Trichomonas vaginalis conserved hypothetical protein 0.0009 0.0009 0.0005
Brugia malayi Serine/threonine protein phosphatase F56C9.1 in chromosomeIII 0.0009 0.001 0.001
Loa Loa (eye worm) acetyltransferase 0.029 0.3468 0.3468
Echinococcus granulosus protein phosphatase 1 catalytic subunit 0.0009 0.001 0.001
Echinococcus multilocularis cpg binding protein 0.0092 0.1028 0.1035
Trichomonas vaginalis conserved hypothetical protein 0.0009 0.0009 0.0005
Trypanosoma cruzi peptidyl-prolyl cis-trans isomerase, putative 0.001 0.0017 0.0018
Loa Loa (eye worm) hypothetical protein 0.0017 0.0107 0.0107
Schistosoma mansoni scm-relatedprotein containing 4 mbt domains (sfmbt) 0.0048 0.0487 0.0487
Brugia malayi nuclear receptor NHR-88 0.003 0.0267 0.0267
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0016 0.0089 0.0089
Brugia malayi exodeoxyribonuclease III family protein 0.0018 0.0121 0.0121
Onchocerca volvulus 0.0012 0.004 0.0037
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.003 0.0267 0.0267
Schistosoma mansoni zinc finger protein 0.0014 0.007 0.007
Brugia malayi nuclear receptor NHR-67 0.0014 0.007 0.007
Trichomonas vaginalis conserved hypothetical protein 0.0019 0.0126 0.0122
Trichomonas vaginalis conserved hypothetical protein 0.0019 0.0132 0.0128
Echinococcus granulosus Nuclear hormone receptor HR96 0.0014 0.007 0.0071
Trichomonas vaginalis conserved hypothetical protein 0.0009 0.0009 0.0005
Trypanosoma brucei chrX additional, unordered contigs 0.0039 0.0374 0.0507
Brugia malayi Nuclear hormone receptor E75 0.0014 0.007 0.007
Echinococcus multilocularis methyl CpG binding domain protein 2 0.0017 0.01 0.01
Schistosoma mansoni hypothetical protein 0.0205 0.2417 0.2417
Onchocerca volvulus 0.0014 0.007 0.0072
Trypanosoma brucei DNA polymerase IV, putative 0.0166 0.1937 0.265
Echinococcus multilocularis protein kinase C binding protein 1 0.0009 0.0009 0.0009
Mycobacterium tuberculosis Fatty-acid-AMP ligase FadD30 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) 0.0017 0.0109 0.0128
Brugia malayi hypothetical protein 0.0016 0.0091 0.0091
Trichomonas vaginalis bromodomain-containing protein, putative 0.0009 0.0009 0.0005
Entamoeba histolytica phosphofructokinase, putative 0.0106 0.1206 0.1698
Loa Loa (eye worm) hypothetical protein 0.0065 0.0691 0.0691
Plasmodium falciparum transportin 0.0011 0.0028 0.0091
Trypanosoma cruzi hypothetical protein, conserved 0.0039 0.0374 0.0507
Schistosoma mansoni tar DNA-binding protein 0.0064 0.0682 0.0682
Brugia malayi Nuclear hormone receptor family member nhr-19 0.003 0.0267 0.0267
Loa Loa (eye worm) hypothetical protein 0.0009 0.0009 0.0009
Schistosoma mansoni rab geranylgeranyl transferase alpha subunit 0.0125 0.1441 0.1441
Schistosoma mansoni dual specificity protein phosphatase 0.0009 0.0004 0.0004
Trichomonas vaginalis conserved hypothetical protein 0.0009 0.0009 0.0005
Trypanosoma brucei pyridine nucleotide-disulphide oxidoreductase, putative 0.0023 0.0183 0.0245
Onchocerca volvulus 0.003 0.0267 0.0301
Echinococcus granulosus dnaJ subfamily B 0.0803 0.9802 1
Toxoplasma gondii isocitrate dehydrogenase 0.0019 0.0129 0.0424
Brugia malayi conserved hypotetical protein 0.0014 0.007 0.007
Trichomonas vaginalis bromodomain-containing protein, putative 0.0009 0.0009 0.0005
Entamoeba histolytica dual specificity protein phosphatase, putative 0.057 0.6918 0.9799
Echinococcus granulosus axis inhibition protein axin 0.0019 0.0126 0.0129
Trichomonas vaginalis bromodomain-containing protein, putative 0.0087 0.0965 0.0961
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0015 0.0085 0.0085
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0019 0.0132 0.0128
Schistosoma mansoni bromodomain-containing protein 3 brd3 0.0009 0.0009 0.0009
Trichomonas vaginalis bromodomain-containing protein, putative 0.0009 0.0009 0.0005
Loa Loa (eye worm) hypothetical protein 0.0019 0.0126 0.0126
Mycobacterium ulcerans phenolpthiocerol synthesis type-I polyketide synthase PpsA 0.002 0.0134 0.0126
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0581 0.706 0.7059
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0091 0.1011 0.1011
Trichomonas vaginalis CAMK family protein kinase 0.0283 0.3386 0.3383
Brugia malayi SET domain containing protein 0.0012 0.004 0.004
Entamoeba histolytica NAD(FAD)-dependent dehydrogenase, putative 0.0023 0.0183 0.0247
Plasmodium falciparum bromodomain protein, putative 0.0009 0.0009 0.003
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.0018 0.0121 0.0122
Toxoplasma gondii pyridine nucleotide-disulfide oxidoreductase domain-containing protein 0.0023 0.0183 0.0602
Echinococcus granulosus Bromodomain containing protein 0.0009 0.0009 0.0009
Brugia malayi nuclear receptor RXR 0.0016 0.0091 0.0091
Schistosoma mansoni 6-phosphofructokinase 0.0106 0.1206 0.1206
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0107 0.1217 0.1217
Loa Loa (eye worm) 6-phosphofructokinase 0.0106 0.1206 0.1206
Trypanosoma brucei DNA polymerase kappa, putative 0.0179 0.2101 0.2875
Trichomonas vaginalis bromodomain-containing protein, putative 0.0009 0.0009 0.0005
Schistosoma mansoni amyloid beta A4 protein related 0.0067 0.0723 0.0723
Loa Loa (eye worm) hypothetical protein 0.0014 0.007 0.007
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.005 0.0511 0.0511
Echinococcus multilocularis importin subunit beta 1 0.0057 0.0603 0.0606
Trichomonas vaginalis CAMK family protein kinase 0.0283 0.3386 0.3383
Giardia lamblia Fructose-bisphosphate aldolase 0.0581 0.706 1
Echinococcus multilocularis axis inhibition protein axin 0.0019 0.0126 0.0127
Loa Loa (eye worm) isocitrate dehydrogenase 0.0019 0.0129 0.0129
Onchocerca volvulus 0.0023 0.0183 0.0203
Loa Loa (eye worm) hypothetical protein 0.0014 0.007 0.007
Leishmania major DNA polymerase kappa, putative,DNA polymerase IV, putative 0.0139 0.1605 0.2189
Trypanosoma brucei Importin-beta N-terminal domain/HEAT-like repeat, putative 0.0011 0.0028 0.0032
Brugia malayi Bromodomain containing protein 0.0009 0.0009 0.0009
Trypanosoma cruzi DNA polymerase beta thumb, putative 0.0084 0.0935 0.1276
Trichomonas vaginalis serine/threonine protein phosphatase, putative 0.0009 0.001 0.0006
Mycobacterium ulcerans long-chain fatty-acid CoA ligase 0.0023 0.0182 0.0173
Echinococcus multilocularis tar DNA binding protein 0.0064 0.0682 0.0686
Trichomonas vaginalis bromodomain-containing protein, putative 0.0009 0.0009 0.0005
Loa Loa (eye worm) hypothetical protein 0.0202 0.2383 0.2383
Leishmania major trypanothione reductase 0.0255 0.304 0.4158
Schistosoma mansoni high voltage-activated calcium channel Cav2A 0.0094 0.1054 0.1054
Mycobacterium tuberculosis Probable isocitrate dehydrogenase [NADP] Icd1 (oxalosuccinate decarboxylase) (IDH) (NADP+-specific ICDH) (IDP) 0.0019 0.0129 0.0153
Brugia malayi RNA, U transporter 1 0.0163 0.191 0.191
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0019 0.0132 0.0128
Brugia malayi Serine/threonine protein phosphatase PP1-beta catalytic subunit 0.0009 0.001 0.001
Schistosoma mansoni tar DNA-binding protein 0.0064 0.0682 0.0682
Mycobacterium tuberculosis Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB 0.0582 0.7071 0.8981
Trichomonas vaginalis hypothetical protein 0.0011 0.0028 0.0024
Loa Loa (eye worm) bromodomain containing protein 0.0024 0.0194 0.0194
Trichomonas vaginalis bromodomain-containing protein, putative 0.0009 0.0009 0.0005
Mycobacterium tuberculosis Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) 0.0018 0.0121 0.0143
Mycobacterium ulcerans Type I modular polyketide synthase 0.0024 0.0193 0.0185
Toxoplasma gondii selenide, water dikinase 0.0023 0.0183 0.0602
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0016 0.0089 0.009
Loa Loa (eye worm) hypothetical protein 0.0048 0.0487 0.0487
Brugia malayi dihydrolipoyl dehydrogenase, mitochondrial precursor, putative 0.0088 0.0984 0.0984
Entamoeba histolytica pyrophosphate-dependent phosphofructokinase 0.0029 0.0248 0.0339
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0023 0.0182 0.0173
Toxoplasma gondii isocitrate dehydrogenase 0.0019 0.0129 0.0424
Trichomonas vaginalis DNA polymerase eta, putative 0.0179 0.2101 0.2098
Echinococcus granulosus zinc finger protein 0.0031 0.0277 0.0282
Toxoplasma gondii SWI2/SNF2 Brahma-like putative 0.0009 0.0009 0.003
Trypanosoma cruzi DNA polymerase eta, putative 0.0202 0.2383 0.3261
Echinococcus multilocularis retinoic acid receptor rxr beta a retinoic acid receptor rxr alpha a retinoic acid receptor rxr alpha 0.0014 0.007 0.007
Trichomonas vaginalis bsu-protein phosphatase, putative 0.0009 0.001 0.0006
Brugia malayi polk-prov protein 0.0092 0.1034 0.1034
Giardia lamblia Thioredoxin reductase 0.0023 0.0183 0.0259
Trichomonas vaginalis regulator of G protein signaling 5, rgs5, putative 0.0019 0.0126 0.0122
Trypanosoma brucei DNA polymerase kappa, putative 0.01 0.1124 0.1536
Echinococcus granulosus importin 5 0.0011 0.0028 0.0028
Trypanosoma brucei peptidyl-prolyl cis-trans isomerase/rotamase, putative 0.0032 0.029 0.0392
Mycobacterium leprae Probable polyketide synthase Pks1 0.0026 0.0211 0.0258
Brugia malayi Nuclear hormone receptor family member nhr-14 0.003 0.0267 0.0267
Echinococcus granulosus voltage gated sodium channel Nav1 alpha subunit 0.004 0.0386 0.0394
Trichomonas vaginalis bromodomain-containing protein, putative 0.0009 0.0009 0.0005
Plasmodium falciparum ATP-dependent 6-phosphofructokinase 0.0029 0.0248 0.0817
Plasmodium vivax ADP-dependent DNA helicase RecQ, putative 0.0014 0.0068 0.0194
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.003 0.0267 0.0267
Echinococcus multilocularis GPCR, family 2 0.0016 0.0089 0.009
Loa Loa (eye worm) hypothetical protein 0.0023 0.0183 0.0183
Wolbachia endosymbiont of Brugia malayi NADPH-dependent glutamate synthase beta chain 0.0023 0.0183 0.1717
Plasmodium falciparum histone acetyltransferase GCN5 0.0077 0.0849 0.2794
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.003 0.0267 0.0267
Echinococcus multilocularis FTZ F1 alpha 0.003 0.0267 0.0269
Schistosoma mansoni hypothetical protein 0.0009 0.0009 0.0009
Leishmania major ATP-dependent phosphofructokinase 0.0106 0.1206 0.1643
Loa Loa (eye worm) Pin1-type peptidyl-prolyl cis-trans isomerase 0.0033 0.0299 0.0299
Plasmodium falciparum bromodomain protein 1 0.0009 0.0009 0.003
Trichomonas vaginalis bromodomain-containing protein, putative 0.0009 0.0009 0.0005
Entamoeba histolytica HEAT repeat domain containing protein 0.0011 0.0028 0.0026
Echinococcus granulosus bloom syndrome protein 0.0021 0.0151 0.0154
Trichomonas vaginalis bromodomain-containing protein, putative 0.0009 0.0009 0.0005
Toxoplasma gondii NADPH-glutathione reductase 0.0088 0.0984 0.3237
Schistosoma mansoni bromodomain containing protein 0.0016 0.0092 0.0092
Trichomonas vaginalis bromodomain-containing protein, putative 0.0009 0.0009 0.0005
Trichomonas vaginalis bromodomain-containing protein, putative 0.0009 0.0009 0.0005
Mycobacterium ulcerans acyl-CoA synthetase 0.0023 0.0182 0.0173
Brugia malayi nuclear hormone receptor 0.0014 0.007 0.007
Trichomonas vaginalis phosphofructokinase, putative 0.0106 0.1206 0.1203
Brugia malayi nuclear receptor RXR 0.0014 0.007 0.007
Trichomonas vaginalis bsu-protein phosphatase, putative 0.0009 0.001 0.0006
Loa Loa (eye worm) CBP-B 0.0009 0.0009 0.0009
Echinococcus multilocularis Bromodomain containing protein 0.0009 0.0009 0.0009
Loa Loa (eye worm) hypothetical protein 0.0019 0.0126 0.0126
Trichomonas vaginalis bromodomain-containing protein, putative 0.0009 0.0009 0.0005
Schistosoma mansoni thyroid hormone receptor 0.003 0.0267 0.0267
Plasmodium vivax GTP-binding nuclear protein RAN/TC4, putative 0.0042 0.0415 0.134
Giardia lamblia Hypothetical protein 0.0009 0.0009 0.0013
Plasmodium vivax holo-[acyl-carrier-protein] synthase, putative 0.0023 0.0178 0.0556
Loa Loa (eye worm) hypothetical protein 0.0054 0.0556 0.0556
Mycobacterium leprae PHENOLPTHIOCEROL SYNTHESIS TYPE-I POLYKETIDE SYNTHASE PPSC 0.0026 0.0211 0.0258
Brugia malayi orphan nuclear receptor NR2E1 0.0014 0.007 0.007
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0017 0.0109 0.01
Echinococcus granulosus histone acetyltransferase KAT2B 0.0087 0.0965 0.0984
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.003 0.0267 0.0267
Echinococcus granulosus histone lysine methyltransferase setb 0.0107 0.1217 0.1242
Trypanosoma cruzi Bromodomain, putative 0.0009 0.0009 0.0007
Onchocerca volvulus 0.003 0.0258 0.029
Echinococcus multilocularis regulator of G protein signaling 7 0.0019 0.0126 0.0127
Onchocerca volvulus Fatty acid synthase homolog 0.0044 0.0433 0.0494
Trichomonas vaginalis conserved hypothetical protein 0.0009 0.0009 0.0005
Plasmodium falciparum acyl-CoA synthetase 0.0017 0.0109 0.0358
Loa Loa (eye worm) nuclear receptor NHR-67 0.0014 0.007 0.007
Trichomonas vaginalis conserved hypothetical protein 0.0009 0.0009 0.0005
Entamoeba histolytica phosphofructokinase, putative 0.0106 0.1206 0.1698
Loa Loa (eye worm) hypothetical protein 0.0023 0.0182 0.0182
Mycobacterium ulcerans polyketide synthase 0.0026 0.0211 0.0203
Echinococcus multilocularis SAM and MBT domain containing protein 0.0048 0.0487 0.049
Echinococcus multilocularis beta adrenergic receptor kinase 0.002 0.0138 0.0139
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0088 0.0984 0.1343
Loa Loa (eye worm) hypothetical protein 0.0019 0.0126 0.0126
Trichomonas vaginalis ap endonuclease, putative 0.0018 0.0121 0.0117
Mycobacterium tuberculosis Probable polyketide synthase Pks1 0.0017 0.0108 0.0127
Echinococcus granulosus protein kinase C binding protein 1 0.0009 0.0009 0.0009
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0019 0.0132 0.0128
Schistosoma mansoni hypothetical protein 0.0296 0.3547 0.3547
Echinococcus granulosus Ankyrin 0.0029 0.0253 0.0258
Loa Loa (eye worm) hypothetical protein 0.003 0.0267 0.0267
Echinococcus granulosus serine:threonine protein phosphatase PP1 gamma 0.0009 0.001 0.001
Schistosoma mansoni regulator of G protein signaling 17 19 20 (rgs17 19 20) 0.0019 0.0126 0.0126
Loa Loa (eye worm) hypothetical protein 0.0038 0.0357 0.0357
Brugia malayi ATPase, AAA family protein 0.0009 0.0009 0.0009
Echinococcus granulosus ecdysone induced protein 78C 0.003 0.0267 0.0273
Trypanosoma cruzi NADPH:adrenodoxin oxidoreductase, mitochondrial, putative 0.0023 0.0183 0.0245
Leishmania major apurinic/apyrimidinic endonuclease-redox protein 0.0018 0.0121 0.0153
Trypanosoma brucei DNA damage repair protein, putative 0.0039 0.0374 0.0507
Trypanosoma cruzi Bromodomain, putative 0.0009 0.0009 0.0007
Trichomonas vaginalis bromodomain-containing protein, putative 0.0009 0.0009 0.0005
Brugia malayi Probable ATP-dependent helicase DHX35 0.0158 0.1846 0.1846
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0088 0.0984 0.1343
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0581 0.706 0.7059
Entamoeba histolytica peptidyl-prolyl cis-trans isomerase, putative 0.0032 0.029 0.0398
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0047 0.0468 0.0465
Trypanosoma cruzi pyridine nucleotide-disulphide oxidoreductase, putative 0.0023 0.0183 0.0245
Trypanosoma cruzi NADH dehydrogenase, putative 0.0023 0.0183 0.0245
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.003 0.0267 0.0273
Schistosoma mansoni kinase 0.0144 0.1668 0.1668
Mycobacterium leprae PROBABLE 6-PHOSPHOFRUCTOKINASE PFKA (PHOSPHOHEXOKINASE) (PHOSPHOFRUCTOKINASE) 0.0106 0.1206 0.1524
Trichomonas vaginalis bromodomain-containing protein, putative 0.0009 0.0009 0.0005
Trichomonas vaginalis conserved hypothetical protein 0.0019 0.0132 0.0128
Loa Loa (eye worm) hypothetical protein 0.003 0.0267 0.0267
Schistosoma mansoni hepatocyte nuclear factor 4-alpha (hnf-4-alpha) 0.0014 0.007 0.007
Loa Loa (eye worm) hypothetical protein 0.0016 0.0091 0.0091
Trypanosoma cruzi 2,4-dienoyl-coa reductase fadh1, putative 0.0023 0.0183 0.0245
Trypanosoma cruzi hypothetical protein, conserved 0.0424 0.5124 0.7019
Trichomonas vaginalis dihydroorotate dehydrogenase, putative 0.0023 0.0183 0.0179
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.003 0.0267 0.0269
Onchocerca volvulus Polycomb protein Sfmbt homolog 0.0048 0.0487 0.0557
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0009 0.0004 0.000000000069197
Loa Loa (eye worm) glutaminase 0.0819 1 1
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.001 0.0021 0.0017
Echinococcus multilocularis bromodomain containing protein 8 0.0009 0.0009 0.0009
Schistosoma mansoni glutamate synthase 0.0023 0.0183 0.0183
Loa Loa (eye worm) hypothetical protein 0.0016 0.0091 0.0091
Giardia lamblia Transcription regulatory protein SNF2 0.0009 0.0009 0.0013
Schistosoma mansoni nuclear hormone receptor 0.0014 0.007 0.007
Brugia malayi BRM protein 0.0009 0.0009 0.0009
Mycobacterium tuberculosis Probable polyketide synthase Pks15 0.001 0.0015 0.0008
Trypanosoma cruzi polo-like protein kinase, putative 0.0283 0.3386 0.4636
Echinococcus multilocularis Regulator of G protein signaling 20 0.0019 0.0126 0.0127
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0088 0.0984 0.1343
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0024 0.0195 0.0199
Toxoplasma gondii exonuclease III APE 0.0018 0.0121 0.0397
Brugia malayi Nuclear hormone receptor E75 0.0014 0.007 0.007
Giardia lamblia Flap structure-specific endonuclease 0.0026 0.0218 0.0308
Brugia malayi Pre-SET motif family protein 0.0621 0.7547 0.7547
Schistosoma mansoni methyl-cpg binding protein mbd 0.0017 0.01 0.01
Echinococcus multilocularis regulator of G protein signaling 0.0019 0.0126 0.0127
Trichomonas vaginalis phosphofructokinase, putative 0.0029 0.0248 0.0244
Trichomonas vaginalis bromodomain-containing protein, putative 0.0009 0.0009 0.0005
Mycobacterium tuberculosis Probable NADH-dependent glutamate synthase (small subunit) GltD (L-glutamate synthase) (L-glutamate synthetase) (NADH-glutamate 0.0023 0.0183 0.0222
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0016 0.0089 0.0091
Leishmania major hypothetical protein, conserved 0.0015 0.0078 0.0095
Brugia malayi Calcitonin receptor-like protein seb-1 0.005 0.0511 0.0511
Trichomonas vaginalis bromodomain-containing protein, putative 0.0009 0.0009 0.0005
Plasmodium falciparum ATP-dependent 6-phosphofructokinase 0.0029 0.0248 0.0817
Mycobacterium tuberculosis Probable oxidoreductase 0.0647 0.7872 1
Echinococcus multilocularis ecdysone induced protein 78C 0.003 0.0267 0.0269
Trichomonas vaginalis 6-phosphofructokinase, putative 0.0029 0.0248 0.0244
Trichomonas vaginalis Citrate lyase beta chain, putative 0.0049 0.0496 0.0492
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative 0.0018 0.0121 0.016
Plasmodium vivax dihydrolipoyl dehydrogenase, apicoplast, putative 0.0088 0.0984 0.3216
Echinococcus granulosus thioredoxin glutathione reductase 0.0257 0.3059 0.3121
Toxoplasma gondii pyridine nucleotide-disulfide oxidoreductase domain-containing protein 0.0023 0.0183 0.0602
Schistosoma mansoni nuclear receptor 0.0014 0.007 0.007
Trichomonas vaginalis disulfide oxidoreductase, putative 0.0023 0.0183 0.0179
Wolbachia endosymbiont of Brugia malayi thioredoxin reductase 0.0023 0.0183 0.1717
Trypanosoma brucei importin beta-1 subunit, putative 0.0057 0.0603 0.0821
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.0014 0.0066 0.0216
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0581 0.706 0.7059
Trichomonas vaginalis conserved hypothetical protein 0.0009 0.0009 0.0005
Mycobacterium ulcerans citrate (pro-3S)-lyase subunit beta 0.0049 0.0496 0.0488
Loa Loa (eye worm) pigment dispersing factor receptor c 0.005 0.0511 0.0511
Brugia malayi alpha keto acid dehydrogenase complex, E3 component, lipoamide dehydrogenase 0.0065 0.0695 0.0695
Echinococcus granulosus PH interacting protein 0.0009 0.0009 0.0009
Brugia malayi oxidoreductase, zinc-binding dehydrogenase family protein 0.0046 0.0461 0.0461
Trichomonas vaginalis conserved hypothetical protein 0.0009 0.0009 0.0005
Schistosoma mansoni sulfide quinone reductase 0.0023 0.0183 0.0183
Brugia malayi Beta-ketoacyl synthase, N-terminal domain containing protein 0.0024 0.0193 0.0193
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.003 0.0267 0.0273
Schistosoma mansoni tar DNA-binding protein 0.0064 0.0682 0.0682
Schistosoma mansoni hypothetical protein 0.0009 0.0009 0.0009
Echinococcus multilocularis transportin 1 0.0011 0.0028 0.0028
Echinococcus multilocularis glutamate synthase 0.0023 0.0183 0.0184
Trichomonas vaginalis bromodomain-containing protein, putative 0.0009 0.0009 0.0005
Schistosoma mansoni protein phosphatase-1 0.0009 0.001 0.001
Trichomonas vaginalis conserved hypothetical protein 0.0019 0.0132 0.0128
Entamoeba histolytica phosphofructokinase, putative 0.0106 0.1206 0.1698
Loa Loa (eye worm) hypothetical protein 0.0019 0.0126 0.0126
Mycobacterium tuberculosis Polyketide synthase Pks12 0.0026 0.0211 0.0258
Trypanosoma brucei mitochondrial DNA polymerase beta-PAK 0.0284 0.3398 0.4653
Schistosoma mansoni CREB-binding protein 1 (SmCBP1) 0.0009 0.0009 0.0009
Echinococcus multilocularis A kinase anchor protein 10, mitochondrial 0.0019 0.0126 0.0127
Mycobacterium ulcerans acyl-CoA synthetase 0.0023 0.0182 0.0173
Brugia malayi ecdysteroid receptor 0.003 0.0267 0.0267
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0088 0.0984 0.1343
Leishmania major importin beta-1 subunit, putative 0.0047 0.0468 0.063
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0184 0.2164 0.2164
Trypanosoma brucei Bromodomain factor 1 0.0009 0.0009 0.0007
Mycobacterium tuberculosis Possible DNA-damage-inducible protein P DinP (DNA polymerase V) (pol IV 2) (DNA nucleotidyltransferase (DNA-directed)) 0.0139 0.1605 0.203
Trypanosoma brucei DNA polymerase kappa, putative 0.01 0.1124 0.1536
Trichomonas vaginalis bromodomain-containing protein, putative 0.0009 0.0009 0.0005
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.003 0.0267 0.0267
Brugia malayi tailless protein 0.0014 0.007 0.007
Plasmodium vivax type II NADH:ubiquinone oxidoreductase, putative 0.0023 0.0183 0.0574
Brugia malayi nuclear hormone receptor 0.003 0.0267 0.0267
Trypanosoma cruzi 2,4-dihydroxyhept-2-ene-1,7-dioic acid aldolase, putative 0.0049 0.0496 0.0674
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0016 0.0089 0.009
Loa Loa (eye worm) hypothetical protein 0.003 0.0267 0.0267
Plasmodium falciparum glutathione reductase 0.0255 0.304 1
Loa Loa (eye worm) bromodomain containing protein 0.0009 0.0009 0.0009
Trichomonas vaginalis lymphoid specific helicase, putative 0.0009 0.0009 0.0005
Echinococcus granulosus transportin 1 0.0011 0.0028 0.0028
Giardia lamblia Ser/Thr protein phosphatase PP1-alpha 2 catalytic subunit 0.0009 0.001 0.0014
Trichomonas vaginalis DNA helicase recq, putative 0.0021 0.0151 0.0147
Trichomonas vaginalis conserved hypothetical protein 0.001 0.0021 0.0017
Trypanosoma brucei mitochondrial DNA polymerase beta 0.06 0.7299 1
Brugia malayi AMP-binding enzyme family protein 0.0023 0.0182 0.0182
Trichomonas vaginalis conserved hypothetical protein 0.0009 0.0009 0.0005
Trichomonas vaginalis protein phosphatase, caeel, putative 0.0009 0.001 0.0006
Loa Loa (eye worm) hypothetical protein 0.002 0.0137 0.0137
Trypanosoma cruzi isocitrate dehydrogenase, putative 0.0019 0.0129 0.0171
Brugia malayi Flap endonuclease-1 0.0026 0.0218 0.0218
Schistosoma mansoni glutamate synthase 0.0023 0.0183 0.0183
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.003 0.0267 0.0269
Wolbachia endosymbiont of Brugia malayi thioredoxin reductase 0.0023 0.0183 0.1717
Trichomonas vaginalis ran, putative 0.0042 0.0415 0.0412
Schistosoma mansoni protein phosphatase type 1 0.0009 0.001 0.001
Mycobacterium tuberculosis Probable polyketide synthase Pks8 0.002 0.0138 0.0165
Loa Loa (eye worm) AGC/GRK/GRK protein kinase 0.002 0.0138 0.0138
Trichomonas vaginalis phosphofructokinase, putative 0.0029 0.0248 0.0244
Leishmania major GTP-binding protein, putative 0.0042 0.0415 0.0557
Entamoeba histolytica hypothetical protein 0.0019 0.0126 0.0166
Trichomonas vaginalis dihydroorotate dehydrogenase, putative 0.0023 0.0183 0.0179
Schistosoma mansoni regulator of G protein signaling 3 rgs3 0.0019 0.0126 0.0126
Leishmania major NADH dehydrogenase, putative 0.0023 0.0183 0.0239
Mycobacterium tuberculosis Probable citrate (pro-3S)-lyase (beta subunit) CitE (citrase) (citratase) (citritase) (citridesmolase) (citrase aldolase) 0.0049 0.0496 0.062
Trichomonas vaginalis bromodomain-containing protein, putative 0.0009 0.0009 0.0005
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0621 0.7547 0.7547
Brugia malayi Regulator of G protein signaling domain containing protein 0.0019 0.0126 0.0126
Leishmania major 4-coumarate:coa ligase-like protein 0.0023 0.0182 0.0237
Echinococcus multilocularis serine:threonine protein phosphatase PP1 gamma 0.0009 0.001 0.001
Brugia malayi Bromodomain containing protein 0.0009 0.0009 0.0009
Trypanosoma brucei isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0019 0.0129 0.0171
Trypanosoma brucei hypothetical protein, conserved 0.0424 0.5124 0.7019
Loa Loa (eye worm) hypothetical protein 0.0009 0.0009 0.0009
Onchocerca volvulus 0.0048 0.0487 0.0557
Trypanosoma brucei polo-like protein kinase 0.0283 0.3386 0.4636
Trichomonas vaginalis bromodomain-containing protein, putative 0.0009 0.0009 0.0005
Mycobacterium tuberculosis NADPH-dependent mycothiol reductase Mtr 0.0255 0.304 0.3855
Loa Loa (eye worm) calcium channel 0.0094 0.1054 0.1054
Brugia malayi Protein kinase domain containing protein 0.003 0.0265 0.0265
Plasmodium falciparum AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0018 0.0121 0.0397
Loa Loa (eye worm) hypothetical protein 0.0014 0.007 0.007
Onchocerca volvulus 0.0014 0.007 0.0072
Mycobacterium ulcerans hypothetical protein 0.0039 0.0374 0.0366
Brugia malayi GTP-binding nuclear protein RAN/TC4 0.0042 0.0415 0.0415
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.003 0.0267 0.0269
Echinococcus multilocularis zinc finger protein 0.0031 0.0277 0.0279
Trypanosoma cruzi Bromodomain, putative 0.0009 0.0009 0.0007
Brugia malayi mbt repeat family protein 0.0048 0.0487 0.0487
Trichomonas vaginalis bromodomain-containing protein, putative 0.0009 0.0009 0.0005
Trypanosoma brucei NADH dehydrogenase 0.0023 0.0183 0.0245
Mycobacterium tuberculosis Conserved hypothetical protein 0.0316 0.3794 0.4814
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0014 0.007 0.0072
Loa Loa (eye worm) hypothetical protein 0.0016 0.0092 0.0092
Loa Loa (eye worm) hypothetical protein 0.0014 0.007 0.007
Echinococcus multilocularis pyridine nucleotide disulfide oxidoreductase 0.0023 0.0183 0.0184
Mycobacterium leprae PHENOLPTHIOCEROL SYNTHESIS TYPE-I POLYKETIDE SYNTHASE PPSE 0.0016 0.0091 0.0106
Trichomonas vaginalis conserved hypothetical protein 0.0009 0.0009 0.0005
Loa Loa (eye worm) hypothetical protein 0.003 0.0267 0.0267
Brugia malayi glutamate synthase 0.0023 0.0183 0.0183
Trichomonas vaginalis bromodomain-containing protein, putative 0.0009 0.0009 0.0005
Echinococcus granulosus endonuclease exonuclease phosphatase 0.0193 0.2278 0.2324
Toxoplasma gondii non-proton pumping type-II NADH dehydrogenase I 0.0023 0.0183 0.0602
Echinococcus granulosus serine:threonine protein phosphatase PP1 gamma 0.0009 0.001 0.001
Trypanosoma brucei DNA polymerase kappa, putative 0.0179 0.2101 0.2875
Entamoeba histolytica glutamate synthase beta subunit, putative 0.0023 0.0183 0.0247
Trypanosoma cruzi bromodomain-containing protein 3 0.0009 0.0009 0.0007
Schistosoma mansoni regulator of G protein signaling 0.0019 0.0126 0.0126
Trichomonas vaginalis bromodomain-containing protein, putative 0.0009 0.0009 0.0005
Echinococcus multilocularis regulator of G protein signaling 3 0.0019 0.0126 0.0127
Echinococcus granulosus glutamate synthase 0.0023 0.0183 0.0187
Brugia malayi latrophilin 2 splice variant baaae 0.0034 0.0316 0.0316
Trypanosoma cruzi peptidyl-prolyl cis-trans isomerase 0.0032 0.029 0.0392
Loa Loa (eye worm) latrophilin receptor protein 2 0.0016 0.0089 0.0089
Trichomonas vaginalis bromodomain-containing protein, putative 0.0009 0.0009 0.0005
Leishmania major ATP-dependent DEAD/H DNA helicase recQ, putative 0.0011 0.0031 0.003
Loa Loa (eye worm) hypothetical protein 0.0047 0.0473 0.0473
Brugia malayi Bromodomain containing protein 0.0009 0.0009 0.0009
Leishmania major protein kinase, putative,polo-like protein kinase, putative 0.0283 0.3386 0.4632
Brugia malayi mbt repeat family protein 0.0048 0.0487 0.0487
Echinococcus multilocularis peregrin 0.0009 0.0009 0.0009
Toxoplasma gondii beta-ketoacyl synthase, N-terminal domain-containing protein 0.0016 0.0088 0.0288
Brugia malayi Bromodomain containing protein 0.0009 0.0009 0.0009
Toxoplasma gondii HEAT repeat-containing protein 0.0057 0.0603 0.1982
Trichomonas vaginalis glutaminase, putative 0.0819 1 1
Schistosoma mansoni retinoid-x-receptor (RXR) 0.003 0.0267 0.0267
Mycobacterium ulcerans ferredoxin reductase 0.0023 0.0183 0.0175
Brugia malayi Latrophilin receptor protein 2 0.0016 0.0089 0.0089
Brugia malayi glutathione reductase 0.0255 0.304 0.304
Mycobacterium tuberculosis Phenolpthiocerol synthesis type-I polyketide synthase PpsD 0.0024 0.0193 0.0234
Toxoplasma gondii GTP-binding nuclear protein ran/tc4 0.0042 0.0415 0.1366
Loa Loa (eye worm) hypothetical protein 0.0016 0.0091 0.0091
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.0042 0.0415 0.0564
Echinococcus multilocularis thyroid hormone receptor alpha 0.003 0.0267 0.0269
Echinococcus granulosus nuclear receptor subfamily 4 group A 0.0014 0.007 0.0071
Trichomonas vaginalis bromodomain containing protein, putative 0.0009 0.0009 0.0005
Trypanosoma cruzi isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0019 0.0129 0.0171
Trichomonas vaginalis CAMK family protein kinase 0.0283 0.3386 0.3383
Toxoplasma gondii histone lysine acetyltransferase GCN5-A 0.0087 0.0965 0.3174
Loa Loa (eye worm) PLK/PLK1 protein kinase 0.0283 0.3386 0.3386
Entamoeba histolytica exodeoxyribonuclease III, putative 0.0018 0.0121 0.0158
Toxoplasma gondii type I fatty acid synthase, putative 0.0017 0.0107 0.035
Echinococcus granulosus regulator of G protein signaling 7 0.0019 0.0126 0.0129
Trichomonas vaginalis conserved hypothetical protein 0.0019 0.0132 0.0128
Trichomonas vaginalis bromodomain containing protein, putative 0.0009 0.0009 0.0005
Toxoplasma gondii 6-phosphofructokinase 0.0029 0.0248 0.0817
Trichomonas vaginalis disulfide oxidoreductase, putative 0.0023 0.0183 0.0179
Loa Loa (eye worm) hypothetical protein 0.0014 0.007 0.007
Mycobacterium tuberculosis Possible dehydrogenase/reductase 0.0023 0.0183 0.0222
Echinococcus multilocularis expressed protein 0.0033 0.0299 0.0301
Schistosoma mansoni disulfide oxidoreductase 0.0023 0.0183 0.0183
Schistosoma mansoni nuclear receptor nhr-48 0.0014 0.007 0.007
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD2 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0023 0.0182 0.022
Schistosoma mansoni helicase 0.0009 0.0009 0.0009
Mycobacterium ulcerans hypothetical protein 0.0023 0.0182 0.0173
Mycobacterium ulcerans NADPH:adrenodoxin oxidoreductase FprA 0.0023 0.0183 0.0175
Trichomonas vaginalis histone acetyltransferase gcn5, putative 0.0009 0.0009 0.0005
Mycobacterium ulcerans NADPH:adrenodoxin oxidoreductase FprA 0.0023 0.0183 0.0175
Echinococcus multilocularis dihydropyrimidine dehydrogenase (NADP+) 0.0023 0.0183 0.0184
Toxoplasma gondii bromodomain-containing protein 0.0009 0.0009 0.003
Mycobacterium leprae Probable NADPH:adrenodoxin oxidoreductase FprA (NADPH-FERREDOXIN REDUCTASE) 0.0023 0.0183 0.0222
Leishmania major mitochondrial DNA polymerase beta 0.06 0.7299 1
Trichomonas vaginalis bromodomain-containing protein, putative 0.0009 0.0009 0.0005
Schistosoma mansoni coup transcription factor 0.003 0.0267 0.0267
Brugia malayi Importin beta-1 subunit 0.0057 0.0603 0.0603
Trypanosoma brucei DNA polymerase kappa, putative 0.0179 0.2101 0.2875
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0088 0.0984 0.1343
Schistosoma mansoni aminoadipate-semialdehyde dehydrogenase 0.0082 0.0903 0.0903
Trichomonas vaginalis conserved hypothetical protein 0.0009 0.0009 0.0005
Trichomonas vaginalis dihydrolipoamide dehydrogenase, putative 0.0023 0.0183 0.0179
Trichomonas vaginalis phosphofructokinase, putative 0.0106 0.1206 0.1203
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0088 0.0984 0.1337
Echinococcus granulosus beta-adrenergic receptor kinase 0.002 0.0138 0.0141
Plasmodium falciparum holo-[acyl-carrier-protein] synthase, putative 0.0023 0.0178 0.0584
Trichomonas vaginalis bromodomain-containing protein, putative 0.0009 0.0009 0.0005
Mycobacterium leprae PROBABLE NADH DEHYDROGENASE NDH 0.0582 0.7071 0.8981
Mycobacterium ulcerans polyketide synthase Pks13 0.0036 0.0341 0.0333
Toxoplasma gondii transporter, cation channel family protein 0.002 0.0137 0.0449
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.003 0.0267 0.0267
Mycobacterium ulcerans acyl-CoA synthetase 0.0023 0.0182 0.0173
Trichomonas vaginalis hypothetical protein 0.0009 0.0009 0.0005
Echinococcus granulosus polycomb protein SCMH1 0.0048 0.0487 0.0497
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0009 0.0008 0.0008
Trypanosoma brucei flap endonuclease-1 (FEN-1), putative 0.0026 0.0218 0.0293
Echinococcus granulosus dna polymerase eta 0.0202 0.2383 0.2431
Brugia malayi Bromodomain containing protein 0.0009 0.0009 0.0009
Brugia malayi 6-phosphofructokinase 0.0106 0.1206 0.1206
Trichomonas vaginalis disulfide oxidoreductase, putative 0.0023 0.0183 0.0179
Echinococcus multilocularis endonuclease exonuclease phosphatase 0.0193 0.2278 0.2293
Schistosoma mansoni tumor necrosis factor receptor related 0.0045 0.0442 0.0442
Echinococcus granulosus dihydrolipoamide dehydrogenase 0.0088 0.0984 0.1004
Echinococcus multilocularis regulator of G protein signaling 3 0.0019 0.0126 0.0127
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0091 0.1011 0.3326
Trichomonas vaginalis bromodomain-containing protein, putative 0.0009 0.0009 0.0005
Mycobacterium ulcerans dihydrolipoamide dehydrogenase 0.0088 0.0984 0.0976
Giardia lamblia Kinase, PLK 0.0283 0.3386 0.4796
Trichomonas vaginalis bromodomain-containing protein, putative 0.0009 0.0009 0.0005
Echinococcus granulosus terminal deoxycytidyl transferase rev1 0.0125 0.1441 0.147
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0016 0.0089 0.0091
Brugia malayi C2-HC type zinc finger protein C.e-MyT1 0.0055 0.0569 0.0569
Toxoplasma gondii histone acetyltransferase TAF1/250 0.0009 0.0009 0.003
Echinococcus multilocularis serine:threonine protein kinase PLK1 0.0283 0.3386 0.3408
Echinococcus multilocularis voltage dependent calcium channel 0.0094 0.1054 0.1061
Plasmodium falciparum glutathione reductase 0.0088 0.0984 0.3237
Loa Loa (eye worm) RecQ helicase 0.0021 0.0151 0.0151
Trichomonas vaginalis pps1 dual specificty phosphatase, putative 0.057 0.6918 0.6917
Trypanosoma brucei DNA polymerase kappa, putative 0.0092 0.1034 0.1412
Echinococcus multilocularis netrin receptor unc 5 0.0029 0.0253 0.0255
Giardia lamblia Endonuclease/Exonuclease/phosphatase 0.0018 0.0121 0.0171
Echinococcus granulosus voltage dependent calcium channel 0.002 0.0137 0.0139
Mycobacterium tuberculosis Probable DNA polymerase IV DinX (pol IV 1) (DNA nucleotidyltransferase (DNA-directed)) 0.0013 0.0057 0.0062
Leishmania major hypothetical protein, conserved 0.0023 0.0183 0.0239
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0019 0.0129 0.013
Mycobacterium tuberculosis Probable NADH dehydrogenase Ndh 0.0582 0.7071 0.8981
Brugia malayi Nuclear hormone receptor-like 1 0.0016 0.0091 0.0091
Plasmodium vivax AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0018 0.0121 0.0368
Echinococcus multilocularis GTP binding nuclear protein Ran 0.0042 0.0415 0.0418
Trypanosoma brucei trypanothione reductase 0.0255 0.304 0.4162
Brugia malayi Pin1-type peptidyl-prolyl cis-trans isomerase, BmPin1 0.0033 0.0299 0.0299
Echinococcus multilocularis voltage dependent calcium channel type d subunit 0.0094 0.1054 0.1061
Schistosoma mansoni hypothetical protein 0.0016 0.0089 0.0089
Brugia malayi Isocitrate dehydrogenase 0.0019 0.0129 0.0129
Loa Loa (eye worm) glutathione reductase 0.0255 0.304 0.304
Loa Loa (eye worm) hypothetical protein 0.0009 0.0009 0.0009
Plasmodium vivax hypothetical protein, conserved 0.0009 0.0009 0.00000015124
Schistosoma mansoni steroid hormone receptor ad4bp 0.003 0.0267 0.0267
Toxoplasma gondii bromodomain-containing protein 0.0009 0.0009 0.003
Toxoplasma gondii ImpB/MucB/SamB family protein 0.0115 0.1316 0.4327
Trypanosoma brucei DNA polymerase kappa, putative 0.0139 0.1605 0.2194
Trypanosoma brucei NADPH:adrenodoxin oxidoreductase, mitochondrial, putative 0.0023 0.0183 0.0245
Trichomonas vaginalis bromodomain-containing protein, putative 0.0009 0.0009 0.0005
Plasmodium vivax SET domain containing protein 0.0014 0.0072 0.0209
Brugia malayi Bromodomain containing protein 0.0009 0.0009 0.0009
Mycobacterium leprae Polyketide synthase Pks13 0.0036 0.0341 0.0423
Schistosoma mansoni hypothetical protein 0.0803 0.9802 0.9802
Onchocerca volvulus 0.0023 0.0182 0.0202
Schistosoma mansoni phd finger protein 0.0009 0.0009 0.0009
Schistosoma mansoni voltage-gated cation channel 0.0094 0.1054 0.1054
Echinococcus granulosus histone acetyltransferase KAT2B 0.0279 0.334 0.3407
Trichomonas vaginalis conserved hypothetical protein 0.0009 0.0009 0.0005
Trichomonas vaginalis bromodomain-containing protein, putative 0.0009 0.0009 0.0005
Echinococcus granulosus nuclear receptor 2DBD gamma 0.003 0.0267 0.0273
Echinococcus multilocularis sodium channel protein 0.004 0.0386 0.0388
Brugia malayi Pre-SET motif family protein 0.0091 0.1011 0.1011
Chlamydia trachomatis holo [acyl-carrier protein] synthase 0.0023 0.0178 0.0787
Brugia malayi Thioredoxin reductase 0.0255 0.304 0.304
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.003 0.0267 0.0273
Giardia lamblia Histone acetyltransferase GCN5 0.0077 0.0849 0.1203
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0019 0.0132 0.0128
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0014 0.007 0.007
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0284 0.3398 0.4653
Echinococcus granulosus methyl CpG binding domain protein 2 0.0017 0.01 0.0102
Trypanosoma cruzi ISWI complex protein 0.0015 0.0078 0.0102
Loa Loa (eye worm) hypothetical protein 0.0019 0.0126 0.0126
Brugia malayi Immunoglobulin I-set domain containing protein 0.0029 0.0253 0.0253
Toxoplasma gondii HEAT repeat-containing protein 0.0011 0.0028 0.0091
Mycobacterium leprae PROBABLE THIOESTERASE TESA 0.002 0.0143 0.0171
Toxoplasma gondii hypothetical protein 0.0009 0.0009 0.003
Schistosoma mansoni hypothetical protein 0.0034 0.0316 0.0316
Plasmodium vivax transportin, putative 0.0011 0.0028 0.0061
Schistosoma mansoni hypothetical protein 0.0009 0.0009 0.0009
Giardia lamblia GTP-binding nuclear protein RAN/TC4 0.0042 0.0415 0.0588
Mycobacterium tuberculosis Phenolpthiocerol synthesis type-I polyketide synthase PpsA 0.0024 0.0193 0.0234
Trypanosoma brucei DNA polymerase kappa, putative 0.0179 0.2101 0.2875
Trichomonas vaginalis bromodomain-containing protein, putative 0.0009 0.0009 0.0005
Toxoplasma gondii serine/threonine phosophatase PP1 0.0009 0.001 0.0032
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.0018 0.0121 0.0121
Trichomonas vaginalis histone acetyltransferase gcn5, putative 0.001 0.0022 0.0018
Trypanosoma cruzi DNA damage repair protein, putative 0.0039 0.0374 0.0507
Trichomonas vaginalis conserved hypothetical protein 0.0009 0.0009 0.0005
Echinococcus multilocularis polycomb protein SCMH1 0.0048 0.0487 0.049
Trypanosoma cruzi Bromodomain, putative 0.0009 0.0009 0.0007
Trichomonas vaginalis conserved hypothetical protein 0.0019 0.0126 0.0122
Toxoplasma gondii thioredoxin reductase 0.0255 0.304 1
Mycobacterium leprae Probable NADH-dependent glutamate synthase (small subunit) GltD (L-glutamate synthase) (L-glutamate synthetase) (NADH-glutamate 0.0023 0.0183 0.0222

Activities

Activity type Activity value Assay description Source Reference
Potency (functional) = 2.8184 um PUBCHEM_BIOASSAY: qHTS Fluorescence Polarization Assay for Inhibitors of MLL CXXC domain - DNA interaction. (Class of assay: confirmatory) [Related pubchem assays: 2698 (Summary assay.)] ChEMBL. No reference
Potency (functional) 16.3601 uM PubChem BioAssay. qHTS for induction of synthetic lethality in tumor cells producing 2HG: qHTS for the HT-1080-NT fibrosarcoma cell line. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) 18.3564 uM PubChem BioAssay. A quantitative high throughput screen for small molecules that induce DNA re-replication in MCF 10a normal breast cells. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) 18.526 uM PUBCHEM_BIOASSAY: Primary qHTS for delayed death inhibitors of the malarial parasite plastid, 48 hour incubation. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID488752, AID488774, AID504848, AID504850] ChEMBL. No reference
Potency (functional) 28.1838 uM PubChem BioAssay. qHTS for Agonist of gsp, the Etiologic Mutation Responsible for Fibrous Dysplasia/McCune-Albright Syndrome: qHTS. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) 79.4328 uM PUBCHEM_BIOASSAY: qHTS Assay for Inhibitors of Histone Lysine Methyltransferase G9a. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID504404] ChEMBL. No reference
Potency (functional) 100 uM PUBCHEM_BIOASSAY: HTS for Inhibitors of HP1-beta Chromodomain Interactions with Methylated Histone Tails. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID488962] ChEMBL. No reference

Phenotypes

Whole-cell/tissue/organism interactions

Species name Source Reference Is orphan
Plasmodium falciparum ChEMBL23

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

Bibliographic References

No literature references available for this target.

If you have references for this compound, please enter them in a user comment (below) or Contact us.