Detailed information for compound 139152

Basic information

Technical information
  • TDR Targets ID: 139152
  • Name: 2-butylsulfanyl-6-[1-(2,6-difluorophenyl)ethy l]-5-methyl-1H-pyrimidin-4-one
  • MW: 338.415 | Formula: C17H20F2N2OS
  • H donors: 1 H acceptors: 3 LogP: 5.13 Rotable bonds: 6
    Rule of 5 violations (Lipinski): 1
  • SMILES: CCCCSc1nc(c(c(n1)O)C)C(c1c(F)cccc1F)C
  • InChi: 1S/C17H20F2N2OS/c1-4-5-9-23-17-20-15(11(3)16(22)21-17)10(2)14-12(18)7-6-8-13(14)19/h6-8,10H,4-5,9H2,1-3H3,(H,20,21,22)
  • InChiKey: DIMOXRYNIBRPQU-UHFFFAOYSA-N  


Substructure search Similarity search

Network

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Synonyms

  • 2-(butylthio)-6-[1-(2,6-difluorophenyl)ethyl]-5-methyl-1H-pyrimidin-4-one
  • 4(3H)-Pyrimidinone, 2-(butylthio)-6-[1-(2,6-difluorophenyl)ethyl]-5-methyl-
  • AIDS-111286
  • AIDS111286

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Brugia malayi hypothetical protein 0.0043 0.0063 0.0197
Schistosoma mansoni ferritin 0.0019 0.0001 0.0001
Brugia malayi Tyrosyl-DNA phosphodiesterase family protein 0.015 0.0346 0.109
Wolbachia endosymbiont of Brugia malayi DNA gyrase, topoisomerase II, B subunit, GyrB 0.0242 0.0589 1
Loa Loa (eye worm) TK/FER protein kinase 0.002 0.0003 0.0008
Schistosoma mansoni thyrotropin-releasing hormone receptor 0.0022 0.0008 0.0008
Leishmania major acetyl-CoA synthetase, putative 0.0023 0.0011 0.0062
Onchocerca volvulus Bile acid receptor homolog 0.0308 0.0765 0.2831
Echinococcus multilocularis rhodopsin orphan GPCR 0.0022 0.0008 0.0008
Schistosoma mansoni neutral sphingomyelinase 0.0021 0.0006 0.0005
Schistosoma mansoni ubiquitin-specific peptidase 8 (C19 family) 0.013 0.0294 0.0294
Loa Loa (eye worm) cytochrome P450 0.0035 0.0042 0.0131
Loa Loa (eye worm) hypothetical protein 0.0059 0.0107 0.0334
Mycobacterium ulcerans cytochrome P450 124A1, Cyp124A1 0.0035 0.0042 0.0176
Trichomonas vaginalis PIKK family atypical protein kinase 0.0026 0.0019 0.0067
Trypanosoma cruzi hypothetical protein, conserved 0.0101 0.0218 0.1274
Leishmania major p-glycoprotein e 0.002 0.0003 0.0013
Trypanosoma cruzi metacaspase, putative 0.002 0.0003 0.0017
Trypanosoma cruzi heat shock protein 85, putative 0.0147 0.0339 0.1986
Trypanosoma brucei C-14 sterol reductase, putative 0.0103 0.0222 0.129
Trichomonas vaginalis heat shock protein, putative 0.0104 0.0225 0.0832
Mycobacterium ulcerans UDP-galactopyranose mutase Glf 0.0645 0.1654 0.7062
Mycobacterium tuberculosis Bifunctional enzyme MbtA: salicyl-AMP ligase (SAL-AMP ligase) + salicyl-S-ArCP synthetase 0.0023 0.0011 0.0043
Trichomonas vaginalis histone deacetylase, putative 0.0156 0.0361 0.1338
Schistosoma mansoni hypothetical protein 0.112 0.291 0.2909
Brugia malayi Cytochrome P450 family protein 0.0035 0.0042 0.0132
Echinococcus granulosus epidermal growth factor receptor 0.0092 0.0194 0.0194
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0025 0.0017 0.0061
Entamoeba histolytica ATP-binding cassette protein, putative 0.002 0.0003 0.0009
Mycobacterium tuberculosis Probable exported protein 0.0021 0.0006 0.002
Echinococcus multilocularis tyrosine protein kinase shark 0.002 0.0003 0.0003
Trypanosoma cruzi metacaspase, putative 0.002 0.0003 0.0017
Echinococcus multilocularis rhodopsin orphan GPCR 0.0022 0.0008 0.0008
Plasmodium falciparum histone deacetylase 1 0.0156 0.0361 0.3382
Trypanosoma cruzi UEV domain/Zinc finger, C3HC4 type (RING finger), putative 0.0063 0.0117 0.0686
Echinococcus granulosus matrix metallopeptidase 7 M10 family 0.0072 0.0141 0.014
Echinococcus granulosus dna polymerase kappa 0.0533 0.136 0.1359
Toxoplasma gondii 3'-5' exonuclease domain-containing protein 0.0033 0.0037 0.0343
Treponema pallidum DNA polymerase III subunit alpha 0.0227 0.0551 0.2171
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0022 0.0008 0.0008
Trichomonas vaginalis phosphofructokinase, putative 0.0124 0.0277 0.1024
Giardia lamblia Sgs1 DNA helicase, putative 0.0172 0.0404 0.1587
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0104 0.0224 0.0223
Loa Loa (eye worm) hypothetical protein 0.004 0.0057 0.0177
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase domain containing protein 0.0023 0.001 0.004
Trypanosoma brucei mitochondrial DNA polymerase beta 0.0665 0.1706 1
Mycobacterium leprae conserved hypothetical protein 0.0052 0.0087 0.0367
Toxoplasma gondii aldehyde dehydrogenase 0.0069 0.0133 0.1239
Echinococcus granulosus tyrosine protein kinase Src64B 0.0057 0.0102 0.0101
Mycobacterium ulcerans cytochrome P450 140A5 Cyp140A5 0.0035 0.0042 0.0176
Echinococcus multilocularis histone deacetylase 0.0094 0.0197 0.0197
Onchocerca volvulus 0.0145 0.0334 0.1237
Echinococcus multilocularis lamin 0.0089 0.0185 0.0185
Echinococcus multilocularis inositol monophosphatase 0.0021 0.0006 0.0006
Entamoeba histolytica DNA topoisomerase III, putative 0.0047 0.0075 0.0295
Schistosoma mansoni tar DNA-binding protein 0.0141 0.0323 0.0323
Entamoeba histolytica endonuclease/exonuclease/phosphatase family protein 0.0021 0.0006 0.0021
Echinococcus multilocularis protein C ets 2 0.0058 0.0104 0.0104
Giardia lamblia DNA topoisomerase III 0.0047 0.0075 0.0288
Schistosoma mansoni hypothetical protein 0.0022 0.0008 0.0008
Trypanosoma cruzi developmentally regulated phosphoprotein, putative 0.0043 0.0062 0.0364
Mycobacterium ulcerans DNA gyrase subunit B 0.0242 0.0589 0.2512
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0978 0.2534 0.9384
Trichomonas vaginalis AGC family protein kinase 0.0067 0.0128 0.0472
Wolbachia endosymbiont of Brugia malayi exonuclease III 0.0104 0.0225 0.3818
Leishmania major heat shock protein 83-1 0.0147 0.0339 0.1986
Plasmodium falciparum AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0104 0.0225 0.2107
Brugia malayi bZIP transcription factor family protein 0.038 0.0955 0.3007
Trypanosoma brucei hypothetical protein, conserved 0.0029 0.0026 0.014
Mycobacterium ulcerans cytochrome P450 185A4 Cyp185A4 0.0074 0.0145 0.0618
Trichomonas vaginalis DEAD box ATP-dependent RNA helicase, putative 0.0028 0.0024 0.0086
Schistosoma mansoni heat shock protein 0.0147 0.0339 0.0339
Loa Loa (eye worm) hypoxia-induced factor 1 0.0839 0.2168 0.6829
Loa Loa (eye worm) TK/FER protein kinase 0.002 0.0003 0.0008
Trypanosoma brucei Endonuclease/Exonuclease/phosphatase family, putative 0.0021 0.0006 0.0017
Echinococcus granulosus tyrosine protein kinase Fyn 0.0057 0.0102 0.0101
Loa Loa (eye worm) hypothetical protein 0.0654 0.1678 0.5286
Echinococcus granulosus NADP dependent isocitrate dehydrogenase 0.0071 0.0138 0.0138
Leishmania major DNA topoisomerase III, putative 0.0113 0.0248 0.1452
Schistosoma mansoni tyrosine kinase 0.002 0.0003 0.0003
Trichomonas vaginalis conserved hypothetical protein 0.0036 0.0045 0.0165
Loa Loa (eye worm) hypothetical protein 0.0022 0.0008 0.0025
Loa Loa (eye worm) hypothetical protein 0.0111 0.0245 0.0769
Echinococcus granulosus survival motor neuron protein 1 0.1049 0.2722 0.2722
Schistosoma mansoni peptide (allatostatin/somatostatin)-like receptor 0.0022 0.0008 0.0008
Brugia malayi hypothetical protein 0.0022 0.0008 0.0026
Trypanosoma brucei heat shock protein 84, putative 0.0066 0.0124 0.0714
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.0021 0.0006 0.0031
Schistosoma mansoni histone deacetylase 0.0156 0.0361 0.0361
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.0214 0.0515 0.1624
Mycobacterium ulcerans acyl-CoA synthetase 0.0079 0.0158 0.067
Trichomonas vaginalis PIKK family atypical protein kinase 0.0032 0.0035 0.0129
Echinococcus multilocularis tyrosine protein kinase Blk 0.0053 0.0091 0.009
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD2 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0079 0.0158 0.067
Brugia malayi hypothetical protein 0.0043 0.0063 0.0197
Schistosoma mansoni biogenic amine (octopamine/dopamine) receptor 0.0359 0.0898 0.0898
Schistosoma mansoni glutaminase 0.0602 0.154 0.154
Chlamydia trachomatis fructose-6-phosphate phosphotransferase 0.0033 0.0038 0.0548
Trichomonas vaginalis PIKK family atypical protein kinase 0.0038 0.0051 0.0187
Loa Loa (eye worm) transcription factor SMAD2 0.1043 0.2706 0.8525
Onchocerca volvulus Eukaryotic initiation factor 4A homolog 0.0028 0.0024 0.0086
Echinococcus multilocularis GTP binding nuclear protein Ran 0.0023 0.0011 0.001
Schistosoma mansoni polyomavirus enhancer activator 3 pea3 0.0058 0.0104 0.0104
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0073 0.0142 0.0817
Mycobacterium leprae PUTATIVE TWO COMPONENT SENSOR HISTIDINE KINASE SENX3 0.0043 0.0062 0.0263
Echinococcus granulosus ferritin 0.0019 0.0001 0.0001
Toxoplasma gondii aurora kinase 0.0067 0.0128 0.1192
Trypanosoma brucei cytochrome P450, putative 0.0074 0.0145 0.0838
Trypanosoma cruzi RNA-editing complex protein MP100, putative 0.0021 0.0006 0.0031
Loa Loa (eye worm) ABC transporter transmembrane region family protein 0.002 0.0003 0.0007
Brugia malayi Mitochondrial import inner membrane translocase subunit Tim17 family protein 0.0046 0.0071 0.0225
Trypanosoma brucei GTP-binding nuclear protein rtb2, putative 0.0023 0.0011 0.0047
Entamoeba histolytica Ran family GTPase 0.0023 0.0011 0.0041
Echinococcus multilocularis peregrin 0.0046 0.0072 0.0072
Mycobacterium ulcerans acyl-CoA synthetase 0.0023 0.0011 0.0043
Trichomonas vaginalis heat shock protein, putative 0.0109 0.0239 0.0882
Trichomonas vaginalis soluble guanylate cyclase gcy, putative 0.0106 0.0229 0.0848
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase domain containing protein 0.013 0.0294 0.116
Plasmodium falciparum ataxin-2 like protein, putative 0.0221 0.0534 0.5
Echinococcus multilocularis TGF beta signal transducer SmadC 0.0071 0.0138 0.0137
Trichomonas vaginalis CMGC family protein kinase 0.0115 0.0253 0.0936
Echinococcus granulosus Nuclear hormone receptor HR96 0.0145 0.0334 0.0334
Leishmania major heat shock protein 83-1 0.0147 0.0339 0.1986
Schistosoma mansoni multidrug resistance protein 0.002 0.0003 0.0002
Brugia malayi XPG I-region family protein 0.0024 0.0013 0.0041
Echinococcus multilocularis tar DNA binding protein 0.0141 0.0323 0.0323
Echinococcus granulosus histone deacetylase 8 0.0066 0.0124 0.0124
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0135 0.0307 0.0307
Onchocerca volvulus 0.002 0.0003 0.001
Brugia malayi MH2 domain containing protein 0.0071 0.0138 0.0434
Echinococcus granulosus cytochrome P450 2K1 0.0035 0.0042 0.0042
Echinococcus granulosus Smad4 0.0071 0.0138 0.0137
Mycobacterium tuberculosis UDP-galactopyranose mutase Glf (UDP-GALP mutase) (NAD+-flavin adenine dinucleotide-requiring enzyme) 0.0645 0.1654 0.7062
Echinococcus multilocularis alpha 1A adrenergic receptor 0.0022 0.0008 0.0008
Brugia malayi DKFZp564C0469 protein 0.0043 0.0063 0.0197
Trichomonas vaginalis mismatch repair protein Mlh1C (mutL homolog) 0.0043 0.0062 0.023
Toxoplasma gondii ImpB/MucB/SamB family protein 0.0241 0.0586 0.5481
Schistosoma mansoni smad 0.0071 0.0138 0.0137
Loa Loa (eye worm) hypothetical protein 0.0022 0.0008 0.0025
Trypanosoma brucei Inositol phosphosphingolipids phospholipase C 0.0021 0.0006 0.0017
Brugia malayi latrophilin 2 splice variant baaae 0.0224 0.0541 0.1705
Loa Loa (eye worm) AUR protein kinase 0.0067 0.0128 0.0401
Echinococcus granulosus histone deacetylase 6 0.0094 0.0197 0.0197
Leishmania major exosome subunit rrp6p homologue, putative 0.0033 0.0037 0.0215
Leishmania major histone deacetylase, putative 0.0156 0.0361 0.2117
Onchocerca volvulus Histone deacetylase 10 homolog 0.0066 0.0124 0.0457
Toxoplasma gondii mitochondrial inner membrane translocase subunit TIM17, putative 0.0046 0.0071 0.0664
Trypanosoma cruzi flap endonuclease-1 (FEN-1), putative 0.0118 0.0261 0.1526
Loa Loa (eye worm) histone deacetylase 0.0094 0.0197 0.0621
Treponema pallidum DNA gyrase, subunit A (gyrA) 0.0082 0.0166 0.065
Mycobacterium ulcerans long-chain fatty-acid CoA ligase 0.0079 0.0158 0.067
Brugia malayi nuclear receptor RXR 0.0145 0.0334 0.1053
Echinococcus multilocularis caspase 0.002 0.0003 0.0003
Trichomonas vaginalis phosphofructokinase, putative 0.0033 0.0038 0.0141
Trichomonas vaginalis conserved hypothetical protein 0.002 0.0003 0.0011
Brugia malayi hypothetical protein 0.0022 0.0008 0.0026
Trichomonas vaginalis prokaryotic DNA topoisomerase, putative 0.0068 0.013 0.0482
Trypanosoma cruzi DNA polymerase kappa, putative 0.0533 0.136 0.7967
Loa Loa (eye worm) nuclear receptor NHR-67 0.0145 0.0334 0.1052
Trypanosoma cruzi Endonuclease/Exonuclease/phosphatase family, putative 0.0021 0.0006 0.0031
Echinococcus granulosus traf and tnf receptor associated protein 0.0021 0.0006 0.0005
Loa Loa (eye worm) phosphofructokinase 0.0124 0.0277 0.0871
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.0087 0.0181 0.1694
Loa Loa (eye worm) cytochrome P450 family protein 0.0035 0.0042 0.0131
Leishmania major peptidyl-prolyl cis-trans isomerase/rotamase, putative,PPIase, putative 0.0146 0.0336 0.1969
Schistosoma mansoni tar DNA-binding protein 0.0141 0.0323 0.0323
Schistosoma mansoni jumonji/arid domain-containing protein 0.0177 0.0418 0.0417
Loa Loa (eye worm) G-protein coupled receptor 0.0022 0.0008 0.0025
Brugia malayi hypothetical protein 0.013 0.0294 0.0925
Schistosoma mansoni amine GPCR 0.0022 0.0008 0.0008
Loa Loa (eye worm) hypothetical protein 0.0163 0.038 0.1197
Trichomonas vaginalis set domain proteins, putative 0.1041 0.27 1
Loa Loa (eye worm) hypothetical protein 0.0145 0.0334 0.1052
Toxoplasma gondii ribonuclease HI protein 0.0027 0.002 0.0188
Schistosoma mansoni caspase-7 (C14 family) 0.002 0.0003 0.0003
Loa Loa (eye worm) AUR protein kinase 0.0067 0.0128 0.0401
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0071 0.0138 0.0138
Entamoeba histolytica phosphofructokinase, putative 0.0124 0.0277 0.1092
Schistosoma mansoni ferritin light chain 0.0019 0.0001 0.0001
Schistosoma mansoni histone deacetylase 0.0156 0.0361 0.0361
Loa Loa (eye worm) histone deacetylase 7A 0.0094 0.0197 0.0621
Loa Loa (eye worm) hypothetical protein 0.0221 0.0534 0.1682
Schistosoma mansoni heat shock protein 0.0147 0.0339 0.0339
Schistosoma mansoni hypothetical protein 0.0214 0.0515 0.0515
Mycobacterium ulcerans glutaminase 0.0602 0.154 0.6573
Schistosoma mansoni alzheimer's disease beta-amyloid related 0.0122 0.0273 0.0273
Brugia malayi hypothetical protein 0.0163 0.038 0.1198
Trypanosoma cruzi metacaspase 5, putative 0.002 0.0003 0.0017
Brugia malayi MH2 domain containing protein 0.0032 0.0034 0.0107
Onchocerca volvulus DNA topoisomerase 2 homolog 0.03 0.0743 0.2751
Trichomonas vaginalis sensory transduction histidine kinase bacterial, putative 0.0043 0.0062 0.023
Echinococcus granulosus ewsr:fli fusion protein type 0.0058 0.0104 0.0104
Echinococcus granulosus potassium voltage gated channel subfamily H 0.0044 0.0066 0.0065
Trypanosoma brucei DNA damage repair protein, putative 0.0101 0.0218 0.1262
Trichomonas vaginalis CAMK family protein kinase 0.0623 0.1596 0.5909
Trypanosoma cruzi metacaspase, putative 0.002 0.0003 0.0017
Schistosoma mansoni importin beta-1 0.0031 0.0032 0.0032
Schistosoma mansoni prokaryotic DNA topoisomerase 0.0113 0.0248 0.0248
Plasmodium vivax GTP-binding nuclear protein RAN/TC4, putative 0.0023 0.0011 0.0096
Echinococcus multilocularis 0.0053 0.0089 0.0088
Loa Loa (eye worm) phosphatidylinositol 3 0.0048 0.0077 0.0241
Schistosoma mansoni loxhd1 0.0045 0.0069 0.0068
Echinococcus granulosus mothers against decapentaplegic 5 0.0071 0.0138 0.0137
Schistosoma mansoni hypothetical protein 0.0104 0.0224 0.0223
Brugia malayi Hsp90 protein 0.0066 0.0124 0.0392
Echinococcus granulosus tyrosine kinase 0.002 0.0003 0.0003
Brugia malayi ecdysteroid receptor 0.0308 0.0765 0.2409
Echinococcus granulosus neuropeptides capa receptor 0.0022 0.0008 0.0008
Trypanosoma cruzi DNA polymerase kappa, putative 0.0533 0.136 0.7967
Mycobacterium ulcerans acyl-CoA synthetase 0.0023 0.0011 0.0043
Trichomonas vaginalis conserved hypothetical protein 0.013 0.0294 0.1088
Onchocerca volvulus Alhambra homolog 0.0032 0.0034 0.0125
Plasmodium vivax isocitrate dehydrogenase [NADP], mitochondrial, putative 0.0071 0.0138 0.1292
Trichomonas vaginalis exonuclease%2C+putative 0.0024 0.0013 0.0047
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0023 0.001 0.0037
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.0308 0.0765 0.0764
Echinococcus granulosus aurora kinase A 0.0067 0.0128 0.0127
Brugia malayi Mitochondrial import inner membrane translocase subunit Tim17 family protein 0.0046 0.0071 0.0225
Onchocerca volvulus DNA topoisomerase 2 homolog 0.03 0.0743 0.2751
Trichomonas vaginalis DNA polymerase IV / kappa, putative 0.0533 0.136 0.5035
Chlamydia trachomatis fructose-6-phosphate phosphotransferase 0.0033 0.0038 0.0548
Trichomonas vaginalis AGC family protein kinase 0.0067 0.0128 0.0472
Echinococcus multilocularis lysine specific demethylase 5A 0.0168 0.0394 0.0394
Echinococcus multilocularis tyrosine protein kinase HCK 0.0035 0.0043 0.0043
Brugia malayi Doublecortin family protein 0.0045 0.0069 0.0216
Schistosoma mansoni serine/threonine protein kinase 0.0115 0.0253 0.0253
Loa Loa (eye worm) aryl Hydrocarbon receptor Associated protein family member 0.0147 0.0337 0.1062
Trichomonas vaginalis conserved hypothetical protein 0.0031 0.0032 0.0117
Echinococcus multilocularis isocitrate dehydrogenase 2 (NADP+) 0.0071 0.0138 0.0138
Loa Loa (eye worm) hypothetical protein 0.0043 0.0063 0.0196
Echinococcus multilocularis gcn5proteinral control of amino acid synthesis 0.0165 0.0386 0.0386
Echinococcus granulosus tyrosine protein kinase Src42A 0.0057 0.0102 0.0101
Chlamydia trachomatis holo [acyl-carrier protein] synthase 0.0052 0.0087 0.138
Echinococcus granulosus RUN 0.0045 0.0069 0.0068
Schistosoma mansoni ubiquitin-specific peptidase 5 (C19 family) 0.0023 0.001 0.001
Plasmodium vivax U4/U6.U5 tri-snRNP-associated protein 2, putative 0.0023 0.001 0.0094
Trypanosoma cruzi histone deacetylase, putative 0.0094 0.0197 0.1155
Trypanosoma cruzi STE group serine/threonine-protein kinase, putative 0.0109 0.0239 0.1397
Schistosoma mansoni single-minded 0.0357 0.0894 0.0894
Entamoeba histolytica protein kinase, putative 0.0021 0.0007 0.0025
Schistosoma mansoni nck2/grb4 0.0022 0.0008 0.0008
Trichomonas vaginalis PIKK family atypical protein kinase 0.0028 0.0025 0.0092
Schistosoma mansoni matrix metallopeptidase-9 (M10 family) 0.0047 0.0075 0.0074
Brugia malayi SH2 domain containing protein 0.002 0.0003 0.0009
Onchocerca volvulus 0.0022 0.0008 0.003
Loa Loa (eye worm) XPG I-region family protein 0.0024 0.0013 0.004
Loa Loa (eye worm) hypothetical protein 0.0043 0.0063 0.0196
Leishmania major target of rapamycin (TOR) kinase 2, putative 0.0048 0.0077 0.0449
Trypanosoma brucei Phosphatidylinositol 3-kinase tor1 0.0048 0.0077 0.0436
Brugia malayi nuclear receptor NHR-88 0.0145 0.0334 0.1053
Toxoplasma gondii hypothetical protein 0.0021 0.0006 0.0056
Loa Loa (eye worm) isocitrate dehydrogenase 0.0071 0.0138 0.0434
Loa Loa (eye worm) jmjC domain-containing protein 0.0045 0.0068 0.0214
Leishmania major hypothetical protein, conserved 0.0024 0.0013 0.0075
Echinococcus multilocularis aryl hydrocarbon receptor 0.0277 0.0681 0.0681
Brugia malayi hypothetical protein 0.0022 0.0008 0.0026
Schistosoma mansoni hypothetical protein 0.0423 0.1069 0.1068
Onchocerca volvulus 0.002 0.0003 0.001
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0022 0.0008 0.0008
Echinococcus granulosus tyrosine protein kinase HCK 0.0035 0.0043 0.0043
Brugia malayi serine/threonine-protein kinase plk-2 0.0623 0.1596 0.5027
Echinococcus granulosus Jumonji AT rich interactive domain 1B 0.0054 0.0092 0.0092
Trypanosoma cruzi Phosphatidylinositol 3-kinase tor1 0.0048 0.0077 0.0449
Giardia lamblia hypothetical protein 0.0024 0.0013 0.0044
Loa Loa (eye worm) hypothetical protein 0.1003 0.2601 0.8194
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0022 0.0008 0.0008
Mycobacterium ulcerans hypothetical protein 0.0079 0.0158 0.067
Schistosoma mansoni nuclear receptor nhr-48 0.0145 0.0334 0.0334
Mycobacterium leprae PROBABLE DNA LIGASE [NAD DEPENDENT] LIGA (POLYDEOXYRIBONUCLEOTIDE SYNTHASE [NAD+]) 0.0043 0.0063 0.0263
Schistosoma mansoni hypothetical protein 0.0104 0.0224 0.0223
Schistosoma mansoni DNA ligase IV 0.0043 0.0063 0.0062
Brugia malayi hypoxia-induced factor 1 0.0839 0.2168 0.6829
Loa Loa (eye worm) matrix metalloproteinase 0.002 0.0002 0.0007
Trichomonas vaginalis PIKK family atypical protein kinase 0.0029 0.0026 0.0094
Mycobacterium ulcerans cytochrome P450 136A2 Cyp136A2 0.0035 0.0042 0.0176
Entamoeba histolytica serine/threonine- protein kinase 6, putative 0.0067 0.0128 0.0503
Plasmodium vivax endoplasmin, putative 0.0147 0.0339 0.3172
Onchocerca volvulus Rap guanine nucleotide exchange factor 1 homolog 0.021 0.0504 0.1865
Mycobacterium ulcerans monophosphatase 0.0021 0.0006 0.0024
Brugia malayi hypothetical protein 0.0022 0.0008 0.0026
Loa Loa (eye worm) hypothetical protein 0.0045 0.0068 0.0214
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0115 0.0253 0.1481
Echinococcus multilocularis histone lysine N methyltransferase, H3 lysine 36 0.002 0.0003 0.0002
Echinococcus granulosus jumonji domain containing protein 0.0044 0.0067 0.0067
Echinococcus multilocularis FKBP12 rapamycin complex associated protein 0.0048 0.0077 0.0077
Loa Loa (eye worm) hypothetical protein 0.0145 0.0334 0.1052
Loa Loa (eye worm) hypothetical protein 0.0586 0.1498 0.4719
Loa Loa (eye worm) hypothetical protein 0.0022 0.0008 0.0025
Echinococcus granulosus somatostatin receptor 0.0022 0.0008 0.0008
Echinococcus multilocularis lamin b receptor 0.0103 0.0222 0.0222
Mycobacterium tuberculosis Possible two component sensor kinase TcrY 0.0043 0.0062 0.0263
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0036 0.0045 0.0165
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0022 0.0008 0.0008
Trypanosoma brucei DNA polymerase kappa, putative 0.0308 0.0765 0.4473
Loa Loa (eye worm) CXXC zinc finger family protein 0.0158 0.0369 0.1161
Toxoplasma gondii endonuclease/exonuclease/phosphatase family protein 0.0021 0.0006 0.0049
Echinococcus multilocularis Peptidase C19, ubiquitin carboxyl terminal hydrolase 2 0.013 0.0294 0.0294
Loa Loa (eye worm) hypothetical protein 0.0329 0.0819 0.2578
Wolbachia endosymbiont of Brugia malayi fructose-1,6-bisphosphatase 0.0204 0.0488 0.8281
Echinococcus multilocularis tyrosine kinase 0.002 0.0003 0.0003
Echinococcus multilocularis jumonji domain containing protein 0.0044 0.0067 0.0067
Loa Loa (eye worm) hypothetical protein 0.0022 0.0008 0.0025
Entamoeba histolytica hypothetical protein 0.0077 0.0153 0.0602
Loa Loa (eye worm) CCR4-NOT transcription complex subunit 6 family protein 0.0021 0.0006 0.0017
Loa Loa (eye worm) hypothetical protein 0.0022 0.0008 0.0025
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.0104 0.0225 0.1319
Trichomonas vaginalis helicase, putative 0.0036 0.0045 0.0165
Trypanosoma cruzi mitochondrial DNA polymerase beta, putative 0.0665 0.1706 1
Mycobacterium tuberculosis Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) 0.0104 0.0225 0.0959
Schistosoma mansoni hypothetical protein 0.0058 0.0104 0.0104
Leishmania major hypothetical protein, conserved 0.0021 0.0006 0.0031
Plasmodium falciparum mitochondrial import inner membrane translocase subunit TIM23, putative 0.0046 0.0071 0.0664
Brugia malayi serine/threonine kinase 12 0.0067 0.0128 0.0402
Brugia malayi Endonuclease/Exonuclease/phosphatase family protein 0.0021 0.0006 0.0018
Loa Loa (eye worm) 3'-5' exonuclease 0.0033 0.0037 0.0116
Brugia malayi putative neuropeptide receptor 0.0022 0.0008 0.0026
Echinococcus multilocularis flap endonuclease GEN 1 0.0024 0.0013 0.0013
Brugia malayi cytoplasmic intermediate filament protein 0.0048 0.0076 0.0239
Brugia malayi Flap endonuclease-1 0.0118 0.0261 0.0821
Trypanosoma brucei inositol polyphosphate 1-phosphatase, putative 0.0021 0.0006 0.0022
Echinococcus multilocularis u4:u6.u5 tri snrnp associated protein 2 0.0023 0.001 0.001
Echinococcus multilocularis ewsr:fli fusion protein type 0.0058 0.0104 0.0104
Loa Loa (eye worm) hypothetical protein 0.0115 0.0255 0.0801
Trypanosoma brucei developmentally regulated phosphoprotein 0.0043 0.0062 0.0351
Toxoplasma gondii phosphofructokinase PFKII 0.0033 0.0038 0.0356
Plasmodium falciparum DNA gyrase subunit B 0.0242 0.0589 0.5512
Loa Loa (eye worm) histone deacetylase 3 0.0156 0.0361 0.1138
Brugia malayi DNA gyrase/topoisomerase IV, A subunit family protein 0.0423 0.1068 0.3365
Loa Loa (eye worm) hypothetical protein 0.0022 0.0008 0.0025
Brugia malayi nuclear hormone receptor family member nhr-6 0.0145 0.0334 0.1053
Trichomonas vaginalis rotamase, putative 0.015 0.0346 0.1279
Entamoeba histolytica hypothetical protein 0.0043 0.0063 0.0245
Entamoeba histolytica histone deacetylase, putative 0.0156 0.0361 0.1425
Echinococcus multilocularis lamin dm0 0.0089 0.0185 0.0185
Toxoplasma gondii heat shock protein 90, putative 0.0147 0.0339 0.3172
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0041 0.0059 0.0217
Entamoeba histolytica protein kinase, putative 0.0067 0.0128 0.0503
Plasmodium falciparum endonuclease/exonuclease/phosphatase family protein, putative 0.0021 0.0006 0.0049
Loa Loa (eye worm) sex muscle abnormal protein 5 0.0022 0.0008 0.0025
Schistosoma mansoni DEAD box ATP-dependent RNA helicase 0.0028 0.0024 0.0023
Chlamydia trachomatis DNA gyrase subunit B 0.0242 0.0589 1
Brugia malayi Nuclear hormone receptor E75 0.0145 0.0334 0.1053
Brugia malayi Raf kinase 0.0048 0.0078 0.0244
Trypanosoma brucei heat shock protein, putative 0.0147 0.0339 0.1975
Loa Loa (eye worm) hypothetical protein 0.0308 0.0765 0.2408
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD7 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0079 0.0158 0.067
Loa Loa (eye worm) hypothetical protein 0.0224 0.0541 0.1704
Echinococcus granulosus snurportin 1 0.0333 0.083 0.0829
Brugia malayi nuclear receptor NHR-88 0.0308 0.0765 0.2409
Echinococcus granulosus tar DNA binding protein 0.0141 0.0323 0.0323
Echinococcus granulosus nuclear receptor subfamily 1 group D 0.0163 0.038 0.038
Mycobacterium ulcerans cytochrome P450 144A4 Cyp144A4 0.0035 0.0042 0.0176
Leishmania major heat shock protein 83-1 0.0147 0.0339 0.1986
Echinococcus multilocularis tyrosine protein kinase Fgr 0.0057 0.0102 0.0101
Echinococcus multilocularis transcription factor btf3 0.0077 0.0153 0.0152
Leishmania major mitogen activated protein kinase, putative,map kinase, putative 0.0115 0.0253 0.1481
Trichomonas vaginalis PIKK family atypical protein kinase 0.0026 0.0019 0.0067
Brugia malayi Cytochrome P450 family protein 0.0074 0.0145 0.0458
Leishmania major heat shock protein 83-1 0.0147 0.0339 0.1986
Loa Loa (eye worm) endonuclease/Exonuclease/phosphatase 0.0021 0.0006 0.0017
Plasmodium vivax hypothetical protein, conserved 0.0032 0.0034 0.0316
Wolbachia endosymbiont of Brugia malayi ribonuclease HI 0.0027 0.002 0.0333
Trichomonas vaginalis conserved hypothetical protein 0.0036 0.0045 0.0165
Plasmodium falciparum DNA topoisomerase VI, b subunit, putative 0.0043 0.0062 0.0581
Echinococcus multilocularis histone deacetylase 7 0.0094 0.0197 0.0197
Trypanosoma brucei unspecified product 0.0482 0.1224 0.7167
Trichomonas vaginalis hypothetical protein 0.0184 0.0437 0.1618
Entamoeba histolytica exosome component 10, putative 0.0033 0.0037 0.0145
Brugia malayi PHD-finger family protein 0.0019 0.0001 0.0004
Trypanosoma brucei isocitrate dehydrogenase, putative 0.0071 0.0138 0.0796
Plasmodium falciparum DNA gyrase subunit A 0.0082 0.0166 0.1547
Schistosoma mansoni phd/f-box containing protein 0.0045 0.0068 0.0068
Trypanosoma cruzi C-14 sterol reductase, putative 0.0103 0.0222 0.1302
Loa Loa (eye worm) AMP-binding enzyme family protein 0.0023 0.0011 0.0034
Trypanosoma cruzi UEV domain/Zinc finger, C3HC4 type (RING finger), putative 0.0063 0.0117 0.0686
Mycobacterium leprae POSSIBLE O-SUCCINYLBENZOIC ACID--CoA LIGASE MENE (OSB-CoA SYNTHETASE) (O-SUCCINYLBENZOATE-CoA SYNTHASE) 0.0023 0.0011 0.0043
Trichomonas vaginalis conserved hypothetical protein 0.0106 0.0229 0.0848
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0308 0.0765 0.0764
Trichomonas vaginalis bromodomain-containing protein, putative 0.0049 0.0078 0.0288
Giardia lamblia Pms1-like protein 0.0043 0.0062 0.0239
Trichomonas vaginalis conserved hypothetical protein 0.0106 0.0229 0.0848
Trichomonas vaginalis flap endonuclease-1, putative 0.0024 0.0013 0.0047
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0056 0.0097 0.0097
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0327 0.0815 0.2566
Echinococcus multilocularis ETS transcription factor Elf 2 0.0058 0.0104 0.0104
Trypanosoma brucei ingi protein (ORF1) 0.0029 0.0026 0.014
Toxoplasma gondii inositol(myo)-1(or 4)-monophosphatase 2, putative 0.0204 0.0488 0.4566
Loa Loa (eye worm) hypothetical protein 0.0327 0.0815 0.2566
Brugia malayi Cathepsin L-like precursor 0.0019 0 0.0001
Brugia malayi F/Y-rich N-terminus family protein 0.0065 0.0121 0.0382
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.002 0.0003 0.0011
Loa Loa (eye worm) 6-phosphofructokinase 0.0124 0.0277 0.0871
Mycobacterium leprae Conserved hypothetical protein 0.0035 0.0042 0.0176
Schistosoma mansoni alpha-1 adrenergic receptor 0.0022 0.0008 0.0008
Trypanosoma cruzi UEV domain/Zinc finger, C3HC4 type (RING finger), putative 0.0063 0.0117 0.0686
Schistosoma mansoni histone deacetylase 1 2 3 0.0066 0.0124 0.0124
Toxoplasma gondii ImpB/MucB/SamB family protein 0.0101 0.0218 0.2035
Trypanosoma brucei inositol-1(or 4)-monophosphatase 1, putative 0.0204 0.0488 0.2848
Echinococcus granulosus tumor susceptibility gene 101 protein 0.0379 0.095 0.095
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.036 0.0901 0.0901
Loa Loa (eye worm) hypothetical protein 0.0022 0.0008 0.0025
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0163 0.038 0.038
Giardia lamblia Hypothetical protein 0.0023 0.001 0.0033
Loa Loa (eye worm) cytochrome P450 family protein 0.0074 0.0145 0.0457
Trypanosoma cruzi DNA polymerase beta thumb, putative 0.0093 0.0197 0.1152
Echinococcus granulosus Aryl hydrocarbon receptor nuclear 0.0106 0.0231 0.023
Trypanosoma cruzi ATP-dependent 6-phosphofructokinase, glycosomal 0.0124 0.0277 0.1621
Schistosoma mansoni tyrosine kinase 0.0171 0.0402 0.0401
Mycobacterium tuberculosis Probable monophosphatase 0.0021 0.0006 0.0024
Loa Loa (eye worm) endonuclease/Exonuclease/phosphatase 0.0021 0.0006 0.0017
Giardia lamblia DNA damage repair protein 0.0101 0.0218 0.0852
Brugia malayi MH1 domain containing protein 0.0039 0.0054 0.017
Entamoeba histolytica hypothetical protein 0.0063 0.0117 0.0462
Echinococcus multilocularis tyrosine protein kinase ABL1 0.002 0.0003 0.0003
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0073 0.0142 0.0817
Mycobacterium tuberculosis Probable cytochrome P450 130 Cyp130 0.0035 0.0042 0.0176
Echinococcus multilocularis ETS domain containing protein Elk 1 0.0058 0.0104 0.0104
Echinococcus granulosus muscleblind protein 0.0329 0.0819 0.0818
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0023 0.0011 0.0035
Trypanosoma cruzi STE/STE11 serine/threonine-protein kinase, putative 0.0109 0.0239 0.1397
Trichomonas vaginalis CMGC family protein kinase 0.0115 0.0253 0.0936
Chlamydia trachomatis two component regulatory system sensor histidine kinase 0.0148 0.0342 0.5755
Giardia lamblia Hypothetical protein 0.0021 0.0006 0.0017
Mycobacterium ulcerans long-chain-fatty-acid-CoA ligase 0.0079 0.0158 0.067
Toxoplasma gondii heat shock protein HSP90 0.0147 0.0339 0.3172
Echinococcus granulosus tyrosyl DNA phosphodiesterase 1 0.015 0.0346 0.0346
Schistosoma mansoni tyrosine kinase 0.0057 0.0102 0.0101
Trypanosoma brucei DNA polymerase kappa, putative 0.0533 0.136 0.7964
Schistosoma mansoni lamin 0.0089 0.0185 0.0185
Loa Loa (eye worm) hypothetical protein 0.0022 0.0008 0.0025
Mycobacterium leprae Probable DNA gyrase (subunit B) GyrB (DNA topoisomerase (ATP-hydrolysing)) (DNA topoisomerase II) (Type II DNA topoisomerase) 0.0082 0.0168 0.0713
Trichomonas vaginalis inositol monophosphatase, putative 0.0204 0.0488 0.1806
Schistosoma mansoni ocrl type II inositol 5-phosphatase 0.0021 0.0006 0.0005
Entamoeba histolytica protein kinase domain containing protein 0.0067 0.0128 0.0503
Brugia malayi aryl hydrocarbon receptor AHR-1 0.0171 0.0401 0.1262
Loa Loa (eye worm) hypothetical protein 0.0058 0.0104 0.0327
Plasmodium falciparum histone acetyltransferase GCN5 0.0044 0.0068 0.0629
Plasmodium vivax replication factor C subunit 1, putative 0.0043 0.0063 0.0582
Loa Loa (eye worm) hypothetical protein 0.0039 0.0054 0.0169
Mycobacterium tuberculosis Probable 6-phosphofructokinase PfkA (phosphohexokinase) (phosphofructokinase) 0.0124 0.0277 0.1179
Leishmania major heat shock protein 83-1 0.0147 0.0339 0.1986
Schistosoma mansoni phosphatidylserine receptor 0.0045 0.0068 0.0068
Loa Loa (eye worm) DNA-binding protein D-ETS-3 0.0058 0.0104 0.0327
Loa Loa (eye worm) hypothetical protein 0.0021 0.0006 0.0017
Brugia malayi ImpB/MucB/SamB family protein 0.0326 0.0812 0.256
Onchocerca volvulus 0.0022 0.0008 0.003
Echinococcus granulosus G protein coupled 5 hydroxytryptamine receptor 0.0022 0.0008 0.0008
Trichomonas vaginalis PIKK family atypical protein kinase 0.0026 0.0018 0.0067
Echinococcus granulosus sex peptide receptor 0.0022 0.0008 0.0008
Echinococcus granulosus protein C ets 2 0.0058 0.0104 0.0104
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0156 0.0361 0.0361
Plasmodium vivax DNA topoisomerase II, putative 0.0423 0.1068 1
Brugia malayi Cathepsin L-like precursor 0.0019 0 0.0001
Schistosoma mansoni ubiquitously transcribed sex (X/Y) chromosome tetratricopeptide repeat protein-related 0.0045 0.0068 0.0068
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.0308 0.0765 0.0764
Loa Loa (eye worm) TK/EGFR protein kinase 0.0171 0.0402 0.1265
Echinococcus multilocularis g-protein coupled receptor 0.0022 0.0008 0.0008
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.0308 0.0765 0.2408
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0204 0.0488 0.1806
Loa Loa (eye worm) hypothetical protein 0.0059 0.0107 0.0334
Echinococcus multilocularis Ataxin 2, N terminal,domain containing protein 0.0099 0.0212 0.0212
Leishmania major eukaryotic initiation factor 4a, putative 0.0028 0.0024 0.0136
Echinococcus granulosus serine:threonine protein kinase PLK1 0.0623 0.1596 0.1595
Echinococcus granulosus biogenic amine 5HT receptor 0.0022 0.0008 0.0008
Loa Loa (eye worm) hypothetical protein 0.0031 0.0032 0.0101
Schistosoma mansoni hypothetical protein 0.0104 0.0224 0.0223
Trypanosoma cruzi DNA topoisomerase IA, putative 0.0068 0.013 0.0762
Entamoeba histolytica heat shock transcription factor, putative 0.0105 0.0229 0.0901
Loa Loa (eye worm) hypothetical protein 0.0022 0.0008 0.0025
Trypanosoma cruzi STE/STE11 serine/threonine-protein kinase, putative 0.0109 0.0239 0.1397
Echinococcus granulosus lamin 0.0089 0.0185 0.0185
Loa Loa (eye worm) hypothetical protein 0.0022 0.0008 0.0025
Brugia malayi hypothetical protein 0.002 0.0003 0.0009
Schistosoma mansoni lamin 0.0089 0.0185 0.0185
Brugia malayi Cathepsin L-like precursor 0.0019 0 0.0001
Loa Loa (eye worm) hypothetical protein 0.0087 0.0181 0.0568
Trypanosoma cruzi transcription factor btf3, putative 0.0077 0.0153 0.0894
Echinococcus granulosus serotonin receptor 0.0022 0.0008 0.0008
Loa Loa (eye worm) hypothetical protein 0.0043 0.0063 0.0196
Trypanosoma cruzi 3-Beta-hydroxysteroid-delta(8), delta(7)-isomerase, putative 0.0157 0.0364 0.213
Mycobacterium ulcerans acyl-CoA synthetase 0.0023 0.0011 0.0043
Leishmania major DNA polymerase eta, putative 0.0466 0.118 0.6917
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0057 0.0102 0.0101
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0036 0.0045 0.0165
Echinococcus multilocularis CCR4 NOT transcription complex subunit 6 0.0021 0.0006 0.0005
Loa Loa (eye worm) unidentified vitellogenin-linked transcript protein 6 0.0022 0.0008 0.0025
Schistosoma mansoni hypothetical protein 0.0099 0.0212 0.0212
Plasmodium falciparum exonuclease I, putative 0.0024 0.0013 0.012
Toxoplasma gondii cytochrome p450 superfamily protein 0.0035 0.0042 0.039
Trypanosoma cruzi UEV domain/Zinc finger, C3HC4 type (RING finger), putative 0.0063 0.0117 0.0686
Brugia malayi HSF-type DNA-binding domain containing protein 0.0105 0.0229 0.072
Mycobacterium tuberculosis DNA gyrase (subunit A) GyrA (DNA topoisomerase (ATP-hydrolysing)) (DNA topoisomerase II) (type II DNA topoisomerase) 0.0082 0.0166 0.0704
Echinococcus granulosus heat shock protein 75 kDa mitochondrial 0.0066 0.0124 0.0124
Brugia malayi jmjC domain containing protein 0.0045 0.0068 0.0215
Brugia malayi topoisomerase 0.0043 0.0063 0.0197
Plasmodium vivax exosome complex exonuclease RRP6, putative 0.0033 0.0037 0.0343
Loa Loa (eye worm) Smad1 0.0071 0.0138 0.0433
Toxoplasma gondii NAC domain-containing protein 0.0077 0.0153 0.1428
Trypanosoma cruzi histone deacetylase, putative 0.0066 0.0124 0.0724
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.0308 0.0765 0.0764
Chlamydia trachomatis DNA gyrase subunit A 0.0082 0.0166 0.2733
Trypanosoma brucei unspecified product 0.0029 0.0026 0.014
Brugia malayi Endonuclease/Exonuclease/phosphatase family protein 0.0021 0.0006 0.0018
Trypanosoma cruzi DNA repair protein RAD2, putative 0.0024 0.0013 0.0075
Loa Loa (eye worm) hypothetical protein 0.0022 0.0008 0.0025
Brugia malayi gonadotropin-releasing hormone receptor 2 0.0022 0.0008 0.0026
Leishmania major DNA topoisomerase III, putative 0.0047 0.0075 0.0437
Loa Loa (eye worm) raf kinase 0.0046 0.0072 0.0225
Echinococcus granulosus inositol polyphosphate 5 phosphatase OCRL 1 0.0021 0.0006 0.0005
Entamoeba histolytica serine/threonine- protein kinase 6 , putative 0.0067 0.0128 0.0503
Brugia malayi mucosa associated lymphoid tissue lymphoma translocation protein 1 0.002 0.0003 0.001
Leishmania major myo-inositol-1 phosphatase, putative 0.0021 0.0006 0.0035
Schistosoma mansoni Smad4 0.0071 0.0138 0.0137
Loa Loa (eye worm) hypothetical protein 0.0308 0.0765 0.2408
Echinococcus multilocularis exonuclease 1 0.0024 0.0013 0.0013
Brugia malayi ImpB/MucB/SamB family protein 0.0466 0.118 0.3719
Brugia malayi hypothetical protein 0.0041 0.0058 0.0183
Leishmania major ABC-thiol transporter 0.002 0.0003 0.0013
Loa Loa (eye worm) hypothetical protein 0.0379 0.095 0.2993
Echinococcus multilocularis tachykinin peptides receptor 99D 0.0022 0.0008 0.0008
Mycobacterium ulcerans cytochrome P450 105Q4 Cyp105Q4 0.0035 0.0042 0.0176
Echinococcus granulosus g protein coupled receptor 0.0022 0.0008 0.0008
Trichomonas vaginalis ribonuclease H1, putative 0.0027 0.002 0.0075
Mycobacterium ulcerans DNA topoisomerase I 0.0068 0.013 0.0553
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0145 0.0334 0.0334
Loa Loa (eye worm) hypothetical protein 0.0097 0.0207 0.0651
Echinococcus granulosus PHD finger protein rhinoceros 0.0032 0.0034 0.0034
Trypanosoma cruzi cysteine peptidase, putative 0.0073 0.0142 0.0829
Brugia malayi G-protein-linked acetylcholine receptor protein 2, putative 0.0022 0.0008 0.0026
Echinococcus multilocularis nuclear factor of activated T cells 5 0.0079 0.0158 0.0158
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0978 0.2534 0.9384
Toxoplasma gondii ICE family protease (caspase) p20 domain-containing protein 0.002 0.0003 0.0027
Schistosoma mansoni tsg101-related 0.0257 0.063 0.063
Leishmania major 4-coumarate:coa ligase-like protein 0.0079 0.0158 0.0923
Echinococcus multilocularis multidrug resistance associated protein 1 0.002 0.0003 0.0002
Echinococcus granulosus caspase 8 0.002 0.0003 0.0003
Trichomonas vaginalis PIKK family atypical protein kinase 0.0038 0.0051 0.0187
Brugia malayi Histone deacetylase family protein 0.0094 0.0197 0.0622
Schistosoma mansoni jumonji/arid domain-containing protein 0.0177 0.0418 0.0417
Trypanosoma cruzi heat shock protein, putative 0.0066 0.0124 0.0726
Leishmania major cathepsin L-like protease 0.0073 0.0142 0.0829
Giardia lamblia Flap structure-specific endonuclease 0.0118 0.0261 0.1022
Trypanosoma cruzi BRCA1 C Terminus (BRCT) domain containing protein, putative 0.0043 0.0063 0.0364
Mycobacterium tuberculosis Two component sensor histidine kinase DevS 0.0043 0.0062 0.0263
Echinococcus granulosus aldehyde dehydrogenase mitochondrial 0.0069 0.0133 0.0132
Plasmodium vivax histone acetyltransferase GCN5, putative 0.0049 0.0078 0.0729
Loa Loa (eye worm) TK/FER protein kinase 0.002 0.0003 0.0008
Treponema pallidum DNA ligase (lig) 0.0043 0.0063 0.0243
Plasmodium falciparum metacaspase-like protein 0.002 0.0003 0.0027
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.0308 0.0765 0.0764
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0093 0.0197 0.1152
Brugia malayi Dopamine receptor protein 1 0.0022 0.0008 0.0026
Echinococcus multilocularis sterol regulatory element binding protein 0.0048 0.0076 0.0076
Echinococcus granulosus lamin dm0 0.0089 0.0185 0.0185
Plasmodium vivax metacaspase 1, putative 0.002 0.0003 0.0027
Brugia malayi Ets-domain containing protein 0.0058 0.0104 0.0328
Trichomonas vaginalis conserved hypothetical protein 0.0036 0.0045 0.0165
Echinococcus granulosus proto oncogene tyrosine protein kinase LCK 0.0057 0.0102 0.0101
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.0089 0.0185 0.0582
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription factor 0.038 0.0955 0.0954
Brugia malayi hypothetical protein 0.0022 0.0008 0.0026
Brugia malayi AKH receptor 0.0022 0.0008 0.0026
Loa Loa (eye worm) doublecortin family protein 0.0045 0.0069 0.0215
Echinococcus granulosus FKBP12 rapamycin complex associated protein 0.0048 0.0077 0.0077
Echinococcus multilocularis c src tyrosine kinase 0.0024 0.0014 0.0014
Trypanosoma brucei DNA polymerase kappa, putative 0.0533 0.136 0.7964
Echinococcus multilocularis mothers against decapentaplegic 5 0.0071 0.0138 0.0137
Trypanosoma cruzi STE group serine/threonine-protein kinase, putative 0.0109 0.0239 0.1397
Trichomonas vaginalis PIKK family atypical protein kinase 0.0036 0.0044 0.0163
Entamoeba histolytica phosphofructokinase, putative 0.0124 0.0277 0.1092
Echinococcus granulosus Transcription factor JmjC domain containing protein 0.0234 0.0568 0.0567
Trypanosoma brucei DNA polymerase beta thumb, putative 0.0093 0.0197 0.1141
Echinococcus granulosus raf serine:threonine protein kinase 0.0048 0.0078 0.0077
Trichomonas vaginalis histone deacetylase 1, 2 ,3, putative 0.0156 0.0361 0.1338
Loa Loa (eye worm) MH1 domain-containing protein 0.0032 0.0034 0.0106
Trypanosoma cruzi Endonuclease/Exonuclease/phosphatase family, putative 0.0021 0.0006 0.0031
Entamoeba histolytica sphingomyelinase C precursor, putative 0.0021 0.0006 0.0021
Loa Loa (eye worm) nuclear hormone receptor-like 1 0.0163 0.038 0.1197
Onchocerca volvulus 0.0089 0.0185 0.0684
Schistosoma mansoni SET domain protein 0.0029 0.0026 0.0026
Trypanosoma cruzi inositol polyphosphate 1-phosphatase, putative 0.0021 0.0006 0.0035
Echinococcus multilocularis epidermal growth factor receptor 0.0171 0.0402 0.0401
Schistosoma mansoni phosphoglucomutase 0.0027 0.002 0.002
Brugia malayi Unidentified vitellogenin-linked transcript protein 6, putative 0.0022 0.0008 0.0026
Onchocerca volvulus 0.0028 0.0024 0.0089
Trypanosoma cruzi Inositol phosphosphingolipids phospholipase C 0.0021 0.0006 0.0031
Echinococcus multilocularis importin subunit beta 1 0.0031 0.0032 0.0032
Brugia malayi Importin beta-1 subunit 0.0031 0.0032 0.0102
Treponema pallidum ribonuclease H (rnhA) 0.0027 0.002 0.0077
Trypanosoma cruzi acetyl-CoA synthetase, putative 0.0023 0.0011 0.0062
Leishmania major ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative 0.013 0.0294 0.1722
Loa Loa (eye worm) hypothetical protein 0.0339 0.0846 0.2664
Loa Loa (eye worm) hypothetical protein 0.002 0.0003 0.0007
Schistosoma mansoni lozenge 0.0063 0.0117 0.0117
Plasmodium vivax ubiquitin carboxyl-terminal hydrolase 13, putative 0.0023 0.001 0.0094
Loa Loa (eye worm) hypothetical protein 0.0079 0.0158 0.0496
Leishmania major developmentally regulated phosphoprotein-like protein 0.0043 0.0062 0.0364
Brugia malayi Latrophilin receptor protein 2 0.0104 0.0224 0.0704
Mycobacterium tuberculosis Probable DNA polymerase III (alpha chain) DnaE1 (DNA nucleotidyltransferase) 0.0228 0.0554 0.2362
Echinococcus granulosus jun protein 0.038 0.0955 0.0954
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0126 0.0282 0.0282
Trypanosoma brucei hypothetical protein, conserved 0.0101 0.0218 0.1262
Brugia malayi hypothetical protein 0.0221 0.0534 0.1683
Echinococcus granulosus histone deacetylase 3 0.0156 0.0361 0.0361
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0022 0.0008 0.0008
Onchocerca volvulus 0.0022 0.0008 0.003
Loa Loa (eye worm) hypothetical protein 0.0022 0.0008 0.0025
Echinococcus granulosus 3'2'5' bisphosphate nucleotidase 1 0.0021 0.0006 0.0006
Leishmania major tyrosyl-DNA phosphodiesterase 1 0.015 0.0346 0.2026
Trypanosoma brucei Emopamil binding protein, putative 0.0157 0.0364 0.2119
Trypanosoma cruzi multidrug resistance-associated protein, putative 0.002 0.0003 0.0013
Onchocerca volvulus Putative neutral sphingomyelinase 0.0021 0.0006 0.0019
Loa Loa (eye worm) hypothetical protein 0.0142 0.0326 0.1025
Plasmodium vivax serine/threonine protein kinase 6, putative 0.0067 0.0128 0.1192
Toxoplasma gondii 4'-phosphopantetheinyl transferase domain-containing protein 0.0052 0.0087 0.0809
Echinococcus granulosus ETS transcription factor Elf 5 0.0058 0.0104 0.0104
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0036 0.0045 0.0165
Echinococcus multilocularis tyrosine protein kinase lyn tyrosine protein kinase blk 0.0057 0.0102 0.0101
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 22 0.0023 0.001 0.001
Echinococcus granulosus retinoic acid receptor rxr beta a 0.042 0.106 0.1059
Trichomonas vaginalis carbon catabolite repressor protein, putative 0.0021 0.0006 0.0019
Onchocerca volvulus 0.0045 0.0069 0.0253
Brugia malayi Bromodomain containing protein 0.0036 0.0045 0.0141
Brugia malayi 3'-5' exonuclease family protein 0.0033 0.0037 0.0117
Schistosoma mansoni rab6-interacting 0.0045 0.0069 0.0068
Leishmania major heat shock protein 83-1 0.0147 0.0339 0.1986
Loa Loa (eye worm) hypothetical protein 0.0089 0.0185 0.0582
Loa Loa (eye worm) hypothetical protein 0.0264 0.0647 0.2038
Plasmodium falciparum DNase I-like protein, putative 0.0021 0.0006 0.0049
Toxoplasma gondii poly(ADP-ribose) polymerase catalytic domain-containing protein 0.0043 0.0063 0.0582
Echinococcus granulosus nibrin 0.0043 0.0063 0.0062
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 8 0.013 0.0294 0.0294
Entamoeba histolytica 3(2),5-bisphosphate nucleotidase, putative 0.0021 0.0006 0.0024
Plasmodium falciparum exodeoxyribonuclease III, putative 0.0021 0.0006 0.0049
Echinococcus granulosus histone deacetylase 7 0.0094 0.0197 0.0197
Brugia malayi Cytochrome P450 family protein 0.0035 0.0042 0.0132
Echinococcus granulosus nuclear receptor nhr 48 0.0145 0.0334 0.0334
Loa Loa (eye worm) hypothetical protein 0.0087 0.0181 0.057
Brugia malayi Tachykinin-like peptides receptor 99D 0.0022 0.0008 0.0026
Trypanosoma brucei Metacaspase-4 0.002 0.0003 0.0003
Plasmodium falciparum histone deacetylase, putative 0.0094 0.0197 0.1845
Schistosoma mansoni caspase-7 (C14 family) 0.0067 0.0127 0.0127
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0073 0.0142 0.0817
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0156 0.0361 0.0361
Wolbachia endosymbiont of Brugia malayi DNA polymerase III alpha subunit 0.0227 0.0551 0.9351
Leishmania major mitochondrial DNA polymerase beta-PAK, putative 0.0315 0.0781 0.4577
Schistosoma mansoni DNA polymerase eta 0.0466 0.118 0.118
Loa Loa (eye worm) nuclear factor I 0.0039 0.0054 0.0169
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0978 0.2534 0.9384
Mycobacterium ulcerans two component sensory transduction histidine kinase MtrB 0.0043 0.0062 0.0263
Mycobacterium leprae conserved hypothetical protein 0.0033 0.0037 0.0154
Trypanosoma cruzi isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0071 0.0138 0.0808
Mycobacterium ulcerans monophosphatase CysQ 0.0021 0.0006 0.0024
Toxoplasma gondii ICE family protease (caspase) p20 domain-containing protein 0.002 0.0003 0.0027
Echinococcus granulosus Nuclear hormone receptor HR96 0.0145 0.0334 0.0334
Entamoeba histolytica DNA topoisomerase III, putative 0.0068 0.013 0.0513
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0022 0.0008 0.0008
Toxoplasma gondii endonuclease/exonuclease/phosphatase family protein 0.0021 0.0006 0.0049
Leishmania major DNA topoisomerase ii 0.0389 0.0977 0.5726
Loa Loa (eye worm) TK/FER protein kinase 0.002 0.0003 0.0008
Wolbachia endosymbiont of Brugia malayi NAD-dependent DNA ligase, Lig 0.0043 0.0063 0.1048
Echinococcus granulosus histone acetyltransferase KAT2B 0.016 0.0374 0.0373
Echinococcus granulosus nuclear receptor subfamily 4 group A 0.0145 0.0334 0.0334
Brugia malayi hypothetical protein 0.004 0.0057 0.0178
Entamoeba histolytica hypothetical protein 0.0052 0.0087 0.0341
Schistosoma mansoni tyrosine kinase 0.002 0.0003 0.0003
Entamoeba histolytica phosphatidylinositol3-kinaseTor2, putative 0.0048 0.0077 0.0302
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.0172 0.0404 0.3777
Trypanosoma cruzi long-chain-fatty-acid-CoA ligase, putative 0.0023 0.0011 0.0062
Schistosoma mansoni biogenic amine receptor 0.0022 0.0008 0.0008
Onchocerca volvulus Inositol monophosphatase 3 homolog 0.0021 0.0006 0.0022
Trichomonas vaginalis conserved hypothetical protein 0.0043 0.0063 0.023
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0156 0.0361 0.0361
Loa Loa (eye worm) hypothetical protein 0.0022 0.0008 0.0025
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0041 0.0059 0.0217
Schistosoma mansoni topbp1 0.0043 0.0063 0.0062
Mycobacterium ulcerans acetyl-CoA synthetase 0.0023 0.0011 0.0043
Trichomonas vaginalis guanylate cyclase, putative 0.0106 0.0229 0.0848
Entamoeba histolytica deoxycytidyl transferase, putative 0.0326 0.0812 0.3206
Trichomonas vaginalis CMGC family protein kinase 0.0115 0.0253 0.0936
Echinococcus granulosus tachykinin peptides receptor 99D 0.0022 0.0008 0.0008
Brugia malayi nuclear receptor NHR-67 0.0145 0.0334 0.1053
Brugia malayi N-terminal motif family protein 0.021 0.0504 0.1587
Trichomonas vaginalis PIKK family atypical protein kinase 0.0038 0.0051 0.0187
Echinococcus multilocularis heat shock protein 90 0.0147 0.0339 0.0339
Loa Loa (eye worm) jmjC domain-containing protein 0.0066 0.0124 0.0389
Schistosoma mansoni ataxia telangiectasia mutated (atm)-related 0.0048 0.0077 0.0077
Loa Loa (eye worm) oxidoreductase 0.0023 0.0011 0.0034
Brugia malayi Pre-SET motif family protein 0.0915 0.2368 0.7459
Mycobacterium ulcerans cytochrome p450 150 cyp150 0.0035 0.0042 0.0176
Trypanosoma cruzi UEV domain/Zinc finger, C3HC4 type (RING finger), putative 0.0063 0.0117 0.0686
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0057 0.0102 0.0101
Loa Loa (eye worm) hypothetical protein 0.0131 0.0296 0.093
Schistosoma mansoni gabp alpha 0.0402 0.1012 0.1012
Brugia malayi Intermediate filament tail domain containing protein 0.0089 0.0185 0.0583
Echinococcus multilocularis mitogen activated protein kinase 0.0115 0.0253 0.0253
Schistosoma mansoni nuclear receptor 0.0145 0.0334 0.0334
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD2 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0079 0.0158 0.067
Trypanosoma brucei DNA polymerase kappa, putative 0.0533 0.136 0.7964
Schistosoma mansoni DNA topoisomerase II 0.0423 0.1068 0.1068
Brugia malayi Serotonin/octopamine receptor family protein 7 0.0359 0.0898 0.2828
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0045 0.007 0.007
Trichomonas vaginalis adenylate and guanylate cyclases, putative 0.0106 0.0229 0.0848
Trichomonas vaginalis PIKK family atypical protein kinase 0.0036 0.0044 0.0163
Echinococcus granulosus tyrosine protein kinase Fps85D 0.002 0.0003 0.0003
Schistosoma mansoni Lamin B receptor (ERG24) 0.0103 0.0222 0.0222
Brugia malayi jmjC domain containing protein 0.0177 0.0418 0.1316
Trypanosoma cruzi hypothetical protein, conserved 0.0063 0.0117 0.0686
Mycobacterium ulcerans two component sensor histidine kinase DevS 0.0043 0.0062 0.0263
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.013 0.0294 0.1088
Loa Loa (eye worm) hypothetical protein 0.0022 0.0008 0.0025
Brugia malayi PAS domain containing protein 0.0357 0.0894 0.2817
Plasmodium vivax hypothetical protein, conserved 0.0043 0.0062 0.0581
Trichomonas vaginalis histone deacetylase, putative 0.0156 0.0361 0.1338
Echinococcus granulosus rhodopsin orphan GPCR 0.0022 0.0008 0.0008
Schistosoma mansoni growth factor receptor-bound protein 0.0022 0.0008 0.0008
Schistosoma mansoni DNA polymerase IV / kappa 0.0101 0.0218 0.0217
Loa Loa (eye worm) TK/FER protein kinase 0.002 0.0003 0.0008
Echinococcus granulosus nuclear factor of activated T cells 5 0.0079 0.0158 0.0158
Loa Loa (eye worm) hypothetical protein 0.0308 0.0765 0.2408
Brugia malayi Tyrosine-protein kinase abl-1 0.0024 0.0014 0.0044
Schistosoma mansoni smad 0.0032 0.0034 0.0034
Leishmania major DNA damage repair protein, putative 0.0101 0.0218 0.1274
Wolbachia endosymbiont of Brugia malayi signal transduction histidine kinase and receiver 0.0043 0.0062 0.1046
Echinococcus multilocularis histone deacetylase 3 0.0156 0.0361 0.0361
Trypanosoma cruzi UEV domain/Zinc finger, C3HC4 type (RING finger), putative 0.0063 0.0117 0.0686
Mycobacterium ulcerans hypothetical protein 0.0033 0.0037 0.0154
Trypanosoma cruzi histone deacetylase, putative 0.0094 0.0197 0.1155
Brugia malayi larval opioid receptor 0.0022 0.0008 0.0026
Schistosoma mansoni CDGSH-type Zn finger-containing protein-like protein 0.0287 0.071 0.0709
Entamoeba histolytica long-chain-fatty-acid--CoA ligase, putative 0.0023 0.0011 0.0042
Mycobacterium ulcerans acyl-CoA synthetase 0.0079 0.0158 0.067
Schistosoma mansoni hypothetical protein 0.0021 0.0006 0.0005
Schistosoma mansoni hypothetical protein 0.0022 0.0008 0.0008
Brugia malayi putative neuropeptide receptor NPR1 0.0022 0.0008 0.0026
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0978 0.2534 0.9384
Brugia malayi Matrixin family protein 0.002 0.0002 0.0008
Echinococcus granulosus tm gpcr rhodopsin 0.0022 0.0008 0.0008
Mycobacterium ulcerans acyl-CoA synthetase 0.0079 0.0158 0.067
Brugia malayi Niemann-Pick C1 protein precursor 0.0111 0.0245 0.077
Entamoeba histolytica DEAD/DEAH box helicase, putative 0.0028 0.0024 0.0092
Trypanosoma cruzi DNA topoisomerase III, putative 0.0068 0.013 0.0762
Loa Loa (eye worm) hypothetical protein 0.0022 0.0008 0.0025
Loa Loa (eye worm) Pin1-type peptidyl-prolyl cis-trans isomerase 0.015 0.0346 0.1088
Trypanosoma cruzi DNA damage repair protein, putative 0.0101 0.0218 0.1274
Trypanosoma brucei Endonuclease/Exonuclease/phosphatase family, putative 0.0021 0.0006 0.0017
Plasmodium falciparum heat shock protein 90, putative 0.0234 0.0569 0.5329
Entamoeba histolytica transcription factor BTF3, putative 0.0077 0.0153 0.0602
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0023 0.001 0.0037
Trichomonas vaginalis conserved hypothetical protein 0.0063 0.0117 0.0433
Trichomonas vaginalis CAMK family protein kinase 0.0623 0.1596 0.5909
Mycobacterium tuberculosis Probable cold-shock DeaD-box protein A homolog DeaD (ATP-dependent RNA helicase dead homolog) 0.0028 0.0024 0.0097
Schistosoma mansoni multidrug resistance protein 0.002 0.0003 0.0002
Wolbachia endosymbiont of Brugia malayi parvulin-like peptidyl-prolyl isomerase, PPID 0.0046 0.007 0.118
Schistosoma mansoni hypothetical protein 0.0022 0.0008 0.0008
Trypanosoma cruzi acetyl-CoA synthetase, putative 0.0023 0.0011 0.0062
Mycobacterium tuberculosis Two component sensor histidine kinase TrcS 0.0043 0.0062 0.0263
Trypanosoma brucei metacaspase MCA3 0.002 0.0003 0.0003
Loa Loa (eye worm) hypothetical protein 0.0145 0.0334 0.1052
Mycobacterium ulcerans DNA polymerase IV 0.0533 0.136 0.5803
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0156 0.0361 0.1137
Echinococcus granulosus histone deacetylase 0.0094 0.0197 0.0197
Schistosoma mansoni hypothetical protein 0.0028 0.0024 0.0024
Schistosoma mansoni proto-oncogene tyrosine-protein kinase abl1 0.0022 0.0008 0.0008
Trypanosoma cruzi mitogen activated protein kinase 4, putative 0.0115 0.0253 0.1481
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0036 0.0045 0.0165
Trypanosoma brucei polo-like protein kinase 0.0623 0.1596 0.935
Plasmodium falciparum JmjC domain-containing protein, putative 0.0045 0.0068 0.0637
Toxoplasma gondii histone deacetylase HDAC1 0.0094 0.0197 0.1845
Brugia malayi Inositol-1 0.0204 0.0488 0.1537
Loa Loa (eye worm) hypothetical protein 0.0156 0.0361 0.1138
Brugia malayi 6-phosphofructokinase 0.0124 0.0277 0.0872
Mycobacterium ulcerans putative regulatory protein 0.0252 0.0615 0.2623
Schistosoma mansoni ets 0.0058 0.0104 0.0104
Mycobacterium leprae Probable two-component sensor kinase 0.0043 0.0062 0.0263
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0023 0.001 0.0059
Trypanosoma cruzi histone deacetylase 1, putative 0.0156 0.0361 0.2117
Loa Loa (eye worm) MH2 domain-containing protein 0.0032 0.0034 0.0106
Loa Loa (eye worm) CYP4Cod1 0.0074 0.0145 0.0457
Schistosoma mansoni growth factor receptor-bound protein 0.0022 0.0008 0.0008
Schistosoma mansoni jumonji domain containing protein 0.0212 0.0511 0.0511
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.0308 0.0765 0.2408
Mycobacterium leprae TWO COMPONENT SENSOR HISTIDINE KINASE PRRB 0.0043 0.0062 0.0263
Echinococcus multilocularis Protein lozenge 0.0063 0.0117 0.0117
Plasmodium falciparum ATP-dependent 6-phosphofructokinase 0.0033 0.0038 0.0356
Echinococcus granulosus endonuclease exonuclease phosphatase 0.0021 0.0006 0.0005
Echinococcus granulosus CCR4 NOT transcription complex subunit 6 0.0021 0.0006 0.0005
Entamoeba histolytica hypothetical protein 0.036 0.0901 0.3557
Echinococcus multilocularis cytoplasmic intermediate filament protein 0.0043 0.0063 0.0063
Mycobacterium tuberculosis Possible DNA-damage-inducible protein P DinP (DNA polymerase V) (pol IV 2) (DNA nucleotidyltransferase (DNA-directed)) 0.0378 0.0948 0.4046
Schistosoma mansoni tyrosyl-DNA phosphodiesterase 0.015 0.0346 0.0346
Loa Loa (eye worm) TK/FER protein kinase 0.002 0.0003 0.0008
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.0104 0.0225 0.0225
Toxoplasma gondii SWI2/SNF2-containing protein 0.0045 0.0068 0.0631
Onchocerca volvulus 0.0022 0.0008 0.003
Entamoeba histolytica Flap nuclease, putative 0.0118 0.0261 0.1028
Loa Loa (eye worm) hypothetical protein 0.0043 0.0062 0.0195
Giardia lamblia Translation initiation factor eIF-4A, putative 0.0028 0.0024 0.0085
Trypanosoma brucei importin beta-1 subunit, putative 0.0031 0.0032 0.0174
Loa Loa (eye worm) hypothetical protein 0.004 0.0057 0.0177
Mycobacterium tuberculosis Two component sensor kinase [second part] 0.0043 0.0062 0.0263
Trichomonas vaginalis histone deacetylase, putative 0.0156 0.0361 0.1338
Echinococcus granulosus tumor protein p63 0.1138 0.2957 0.2957
Schistosoma mansoni polymyositis/scleroderma autoantigen-related 0.0033 0.0037 0.0037
Loa Loa (eye worm) hypothetical protein 0.0504 0.1282 0.4038
Trypanosoma cruzi Endonuclease/Exonuclease/phosphatase family, putative 0.0021 0.0006 0.0031
Giardia lamblia Kinase, PLK 0.0623 0.1596 0.6295
Trichomonas vaginalis conserved hypothetical protein 0.0036 0.0045 0.0165
Plasmodium vivax endonuclease/exonuclease/phosphatase domain containing protein 0.0021 0.0006 0.0049
Onchocerca volvulus 0.002 0.0003 0.001
Echinococcus granulosus ETS transcription factor Elf 2 0.0058 0.0104 0.0104
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.0021 0.0006 0.0031
Plasmodium falciparum acyl-CoA synthetase 0.0059 0.0105 0.0982
Echinococcus granulosus alpha 1A adrenergic receptor 0.0022 0.0008 0.0008
Mycobacterium ulcerans hypothetical protein 0.0393 0.0989 0.422
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0023 0.001 0.0037
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 22 0.0023 0.001 0.001
Schistosoma mansoni endoplasmin 0.0147 0.0339 0.0339
Schistosoma mansoni hypothetical protein 0.0339 0.0845 0.0844
Brugia malayi aryl hydrocarbon receptor nuclear translocator protein, putative 0.0045 0.0068 0.0213
Leishmania major heat shock protein 83-1 0.0147 0.0339 0.1986
Echinococcus granulosus phd:f box containing protein 0.0045 0.0068 0.0068
Entamoeba histolytica ATP-binding cassette protein, putative 0.002 0.0003 0.0009
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0104 0.0224 0.0223
Leishmania major apurinic/apyrimidinic endonuclease-redox protein 0.0104 0.0225 0.1319
Echinococcus multilocularis rhodopsin orphan GPCR 0.0022 0.0008 0.0008
Plasmodium vivax AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0104 0.0225 0.2107
Loa Loa (eye worm) DNA topoisomerase III beta-1 0.0047 0.0075 0.0235
Echinococcus multilocularis neuropeptide Y receptor 0.0022 0.0008 0.0008
Schistosoma mansoni xp-G/rad2 DNA repair endonuclease family member 0.0024 0.0013 0.0013
Echinococcus multilocularis serine:threonine protein kinase PLK1 0.0623 0.1596 0.1595
Schistosoma mansoni ubiquitin-specific peptidase 2 (C19 family) 0.013 0.0294 0.0294
Leishmania major lanosterol 14-alpha-demethylase, putative 0.0035 0.0042 0.0244
Echinococcus granulosus neuropeptide s receptor 0.0543 0.1385 0.1384
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0053 0.0091 0.009
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0104 0.0224 0.0223
Schistosoma mansoni lipoxygenase 0.0197 0.0471 0.047
Toxoplasma gondii 6-phosphofructokinase 0.0033 0.0038 0.0356
Mycobacterium ulcerans two component system response phosphate sensor kinase, PhoR 0.0043 0.0062 0.0263
Loa Loa (eye worm) TOPoisomerase family member 0.0423 0.1068 0.3364
Trichomonas vaginalis importin beta-1, putative 0.0025 0.0017 0.0061
Echinococcus granulosus eukaryotic initiation factor 4A 0.0028 0.0024 0.0023
Brugia malayi acetyltransferase, GNAT family protein 0.0165 0.0386 0.1216
Schistosoma mansoni polycystin 1-related 0.0045 0.0069 0.0068
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0055 0.0095 0.0095
Loa Loa (eye worm) hypothetical protein 0.0135 0.0307 0.0967
Trichomonas vaginalis DNA topoisomerase II, putative 0.0423 0.1068 0.3955
Loa Loa (eye worm) hypothetical protein 0.0022 0.0008 0.0025
Trichomonas vaginalis DEAD box ATP-dependent RNA helicase, putative 0.0028 0.0024 0.0086
Schistosoma mansoni serine/threonine protein kinase 0.0623 0.1596 0.1595
Wolbachia endosymbiont of Brugia malayi topoisomerase IA, TopA 0.0113 0.0248 0.4204
Echinococcus multilocularis tumor protein p63 0.1138 0.2957 0.2957
Loa Loa (eye worm) jmjC domain-containing protein 0.0177 0.0418 0.1315
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0115 0.0253 0.1481
Trypanosoma cruzi sterol C-24 reductase, putative 0.0103 0.0222 0.1302
Echinococcus granulosus histone lysine methyltransferase setb 0.0135 0.0307 0.0307
Echinococcus granulosus geminin 0.112 0.291 0.2909
Echinococcus multilocularis tumor susceptibility gene 101 protein 0.0379 0.095 0.095
Echinococcus multilocularis ETS transcription factor Elf 1 0.0058 0.0104 0.0104
Trichomonas vaginalis ran, putative 0.0023 0.0011 0.0038
Trypanosoma cruzi polo-like protein kinase, putative 0.0623 0.1596 0.9351
Trypanosoma brucei protein kinase, putative 0.0115 0.0253 0.147
Trypanosoma cruzi hypothetical protein, conserved 0.0063 0.0117 0.0686
Leishmania major DNA polymerase kappa, putative 0.0378 0.0948 0.5556
Onchocerca volvulus Heat shock protein 75 kDa, mitochondrial homolog 0.0066 0.0124 0.0459
Trypanosoma cruzi DNA topoisomerase III, putative 0.0047 0.0075 0.0437
Schistosoma mansoni histone deacetylase hda2 0.01 0.0214 0.0213
Mycobacterium tuberculosis Probable aldehyde dehydrogenase 0.0069 0.0133 0.0563
Trypanosoma brucei DNA topoisomerase II alpha, putative 0.0389 0.0977 0.572
Trichomonas vaginalis PIKK family atypical protein kinase 0.0026 0.0018 0.0067
Brugia malayi AMP-binding enzyme family protein 0.0079 0.0158 0.0497
Schistosoma mansoni myosin xvIII 0.0022 0.0008 0.0008
Leishmania major heat shock protein, putative 0.0066 0.0124 0.0726
Brugia malayi Nuclear hormone receptor-like 1 0.0163 0.038 0.1198
Brugia malayi ATP dependent DNA ligase C terminal region family protein 0.0043 0.0063 0.0197
Mycobacterium tuberculosis Conserved protein 0.0043 0.0062 0.0263
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0022 0.0008 0.0008
Trypanosoma cruzi JmjC domain, hydroxylase, putative 0.0045 0.0068 0.0399
Brugia malayi Muscleblind-like protein 0.0329 0.0819 0.2579
Mycobacterium ulcerans phosphopantetheinyl transferase, PptII 0.0052 0.0087 0.0367
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0145 0.0334 0.0334
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0023 0.001 0.0037
Leishmania major mitochondrial DNA polymerase beta 0.0665 0.1706 1
Schistosoma mansoni hypothetical protein 0.0021 0.0006 0.0006
Mycobacterium leprae possible inositol monophosphatase SubH (IMPase) (inositol-1-phosphatase) (I-1-Pase ). 0.0182 0.0432 0.1839
Brugia malayi RNA, U transporter 1 0.0089 0.0184 0.0581
Onchocerca volvulus 0.0023 0.0011 0.0039
Toxoplasma gondii heat shock protein 75, putative 0.0066 0.0124 0.1161
Loa Loa (eye worm) hypothetical protein 0.002 0.0003 0.0008
Mycobacterium tuberculosis Phenyloxazoline synthase MbtB (phenyloxazoline synthetase) 0.0023 0.0011 0.0043
Loa Loa (eye worm) hypothetical protein 0.0022 0.0008 0.0025
Trypanosoma cruzi polo-like protein kinase, putative 0.0623 0.1596 0.9351
Onchocerca volvulus Dopamine\/Ecdysteroid receptor homolog 0.0022 0.0008 0.003
Loa Loa (eye worm) acetyltransferase 0.0165 0.0386 0.1215
Loa Loa (eye worm) neuropeptide F receptor 0.0022 0.0008 0.0025
Entamoeba histolytica recQ family DNA helicase 0.0087 0.0181 0.0714
Brugia malayi RE15519p 0.0022 0.0008 0.0026
Plasmodium vivax basic transcription factor 3b, putative 0.0077 0.0153 0.1428
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0978 0.2534 0.9384
Mycobacterium ulcerans cytochrome P450 143A3 Cyp143A3 0.0035 0.0042 0.0176
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.0308 0.0765 0.2408
Trichomonas vaginalis phosphofructokinase, putative 0.0033 0.0038 0.0141
Brugia malayi Pre-SET motif family protein 0.0135 0.0307 0.0968
Trypanosoma cruzi Eukaryotic initiation factor 4A-1 0.0028 0.0024 0.0136
Loa Loa (eye worm) hypothetical protein 0.0022 0.0008 0.0025
Schistosoma mansoni peptide (FMRFamide/neurokinin-3)-like receptor 0.0022 0.0008 0.0008
Trypanosoma cruzi DNA polymerase eta, putative 0.0466 0.118 0.6917
Loa Loa (eye worm) RNA recognition domain-containing protein domain-containing protein 0.0141 0.0323 0.1017
Loa Loa (eye worm) histone deacetylase 1 0.0156 0.0361 0.1138
Trichomonas vaginalis phosphofructokinase, putative 0.0033 0.0038 0.0141
Trichomonas vaginalis PIKK family atypical protein kinase 0.0026 0.0019 0.0067
Echinococcus granulosus acetyl coenzyme A synthetase cytoplasmic 0.0023 0.0011 0.0011
Loa Loa (eye worm) RecQ helicase 0.0322 0.08 0.252
Mycobacterium ulcerans DNA polymerase IV 0.0533 0.136 0.5803
Trypanosoma brucei DNA polymerase kappa, putative 0.0533 0.136 0.7964
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0308 0.0765 0.0764
Echinococcus multilocularis caspase 2 0.0067 0.0127 0.0127
Echinococcus granulosus synaptojanin 1 0.0021 0.0006 0.0005
Echinococcus granulosus histone deacetylase 6 0.01 0.0214 0.0213
Echinococcus multilocularis heat shock protein 90 0.0105 0.0227 0.0226
Wolbachia endosymbiont of Brugia malayi heat shock protein 90 0.0109 0.0239 0.4041
Trypanosoma cruzi Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase, putative 0.0043 0.0062 0.0364
Onchocerca volvulus 0.0276 0.068 0.2517
Plasmodium vivax acetyl-CoA synthetase, putative 0.0023 0.0011 0.01
Brugia malayi Protein kinase domain containing protein 0.002 0.0003 0.0009
Mycobacterium ulcerans peptide synthetase Nrp (peptide synthase) 0.0023 0.0011 0.0043
Echinococcus multilocularis Transcription factor, JmjC domain containing protein 0.0234 0.0568 0.0567
Loa Loa (eye worm) hypothetical protein 0.0172 0.0404 0.1271
Echinococcus granulosus tyrosine protein kinase shark 0.002 0.0003 0.0003
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0025 0.0017 0.0061
Trypanosoma brucei DNA polymerase eta, putative 0.0466 0.118 0.6913
Entamoeba histolytica hypothetical protein 0.0025 0.0017 0.0065
Loa Loa (eye worm) hypothetical protein 0.0071 0.0138 0.0432
Echinococcus multilocularis serotonin receptor 0.0022 0.0008 0.0008
Schistosoma mansoni peptidase 0.002 0.0004 0.0003
Echinococcus granulosus histone deacetylase 6 0.0094 0.0197 0.0197
Brugia malayi Endonuclease/Exonuclease/phosphatase family protein 0.0021 0.0006 0.0018
Leishmania major target of rapamycin (TOR) kinase 1, putative 0.0048 0.0077 0.0449
Loa Loa (eye worm) hypothetical protein 0.0045 0.0069 0.0215
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0308 0.0765 0.2409
Loa Loa (eye worm) jmjC domain-containing protein 0.0045 0.0068 0.0214
Trichomonas vaginalis PIKK family atypical protein kinase 0.0036 0.0044 0.0163
Toxoplasma gondii DNA gyrase/topoisomerase IV, A subunit domain-containing protein 0.0082 0.0166 0.1547
Echinococcus granulosus heat shock protein 0.0147 0.0339 0.0339
Brugia malayi histone deacetylase 11 0.0066 0.0124 0.039
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.0023 0.0011 0.006
Trypanosoma brucei JmjC domain, hydroxylase, putative 0.0045 0.0068 0.0386
Plasmodium falciparum ATP-dependent 6-phosphofructokinase 0.0033 0.0038 0.0356
Echinococcus multilocularis tyrosine protein kinase Src42A 0.0051 0.0085 0.0085
Loa Loa (eye worm) pax transcription factor protein 2 0.0813 0.2098 0.6608
Loa Loa (eye worm) histone methyltransferase 0.0055 0.0095 0.03
Echinococcus granulosus caspase 2 0.0067 0.0127 0.0127
Echinococcus granulosus ETS transcription factor Elf 2 0.0058 0.0104 0.0104
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.0308 0.0765 0.0764
Entamoeba histolytica exonuclease, putative 0.0024 0.0013 0.005
Trichomonas vaginalis heat shock protein, putative 0.0147 0.0339 0.1255
Onchocerca volvulus 0.0022 0.0008 0.003
Leishmania major heat shock protein 83-1 0.0147 0.0339 0.1986
Echinococcus granulosus mitogen activated protein kinase 3 0.0115 0.0253 0.0253
Echinococcus granulosus hypothetical protein 0.0022 0.0008 0.0008
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD7 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0056 0.0097 0.041
Echinococcus granulosus cdgsh iron sulfur domain containing protein 0.0271 0.0667 0.0666
Mycobacterium tuberculosis Probable cytochrome P450 128 Cyp128 0.0035 0.0042 0.0176
Loa Loa (eye worm) nuclear receptor nhr-7B 0.0145 0.0334 0.1052
Loa Loa (eye worm) melatonin receptor type 1A 0.0022 0.0008 0.0025
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0022 0.0008 0.0008
Trypanosoma brucei histone deacetylase 3 0.0094 0.0197 0.1143
Trypanosoma cruzi DNA damage repair protein, putative 0.0101 0.0218 0.1274
Entamoeba histolytica acyl-CoA synthetase, putative 0.0079 0.0158 0.0621
Trichomonas vaginalis DNA polymerase eta, putative 0.0533 0.136 0.5035
Trypanosoma brucei isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0071 0.0138 0.0796
Mycobacterium tuberculosis Probable DNA polymerase IV DinX (pol IV 1) (DNA nucleotidyltransferase (DNA-directed)) 0.0051 0.0086 0.0362
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0036 0.0045 0.0165
Echinococcus multilocularis ATP dependent DNA helicase Q1 0.0172 0.0404 0.0403
Onchocerca volvulus Putative DNA topoisomerase 2, mitochondrial 0.03 0.0743 0.2751
Trichomonas vaginalis conserved hypothetical protein 0.0036 0.0045 0.0165
Mycobacterium leprae POSSIBLE MONOPHOSPHATASE CYSQ 0.0021 0.0006 0.0024
Echinococcus multilocularis tyrosine protein kinase lyn lyn a protein tyrosine kinase lymphocyte specific protein tyrosine kinase 0.0057 0.0102 0.0101
Trypanosoma brucei heat shock protein, putative 0.0147 0.0339 0.1975
Mycobacterium leprae Probable monophosphatase 0.0021 0.0006 0.0024
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD8 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0023 0.0011 0.0043
Brugia malayi MH2 domain containing protein 0.0071 0.0138 0.0434
Trypanosoma cruzi cysteine peptidase, putative 0.0073 0.0142 0.0829
Echinococcus multilocularis histone deacetylase 6 0.0094 0.0197 0.0197
Trypanosoma brucei histone deacetylase 1 0.0156 0.0361 0.2106
Trichomonas vaginalis phosphofructokinase, putative 0.0033 0.0038 0.0141
Plasmodium falciparum importin beta, putative 0.0031 0.0032 0.03
Brugia malayi polk-prov protein 0.0308 0.0765 0.2409
Trichomonas vaginalis chromosome transmission fidelity factor, putative 0.0043 0.0063 0.023
Trichomonas vaginalis CAMK family protein kinase 0.0623 0.1596 0.5909
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0073 0.0142 0.0817
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0022 0.0008 0.0008
Trichomonas vaginalis ap endonuclease, putative 0.0104 0.0225 0.0834
Brugia malayi nuclear hormone receptor 0.0308 0.0765 0.2409
Brugia malayi small heat shock protein 0.0654 0.1678 0.5287
Leishmania major hypothetical protein, conserved 0.0021 0.0006 0.0031
Echinococcus multilocularis DNA topoisomerase 3 beta 1 0.0047 0.0075 0.0075
Brugia malayi Amyloid A4 extracellular domain containing protein 0.0336 0.0837 0.2637
Echinococcus multilocularis 6 phosphofructokinase 0.0124 0.0277 0.0277
Trypanosoma brucei heat shock protein, putative 0.0147 0.0339 0.1975
Brugia malayi MH1 domain containing protein 0.0071 0.0138 0.0434
Plasmodium vivax histone deacetylase, putative 0.0094 0.0197 0.1845
Trichomonas vaginalis heat shock protein, putative 0.0105 0.0227 0.0838
Echinococcus granulosus histone acetyltransferase KAT2B 0.0049 0.0078 0.0078
Brugia malayi DNA topoisomerase II, alpha isozyme 0.0423 0.1068 0.3365
Giardia lamblia DNA topoisomerase III 0.0068 0.013 0.0507
Loa Loa (eye worm) hypothetical protein 0.0079 0.0158 0.0496
Trypanosoma brucei Eukaryotic initiation factor 4A-1 0.0028 0.0024 0.0123
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0145 0.0334 0.0334
Trypanosoma cruzi DNA topoisomerase III, putative 0.0068 0.013 0.0762
Entamoeba histolytica serine/threonine protein kinase, putative 0.0623 0.1596 0.6297
Plasmodium vivax 6-phosphofructokinase, putative 0.0033 0.0038 0.0356
Toxoplasma gondii eukaryotic initiation factor-4A, putative 0.0028 0.0024 0.0217
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.0308 0.0765 0.2831
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD35 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0056 0.0097 0.041
Brugia malayi RNase H family protein 0.0027 0.002 0.0064
Entamoeba histolytica inositol polyphosphate-5-phosphatase, putative 0.0021 0.0006 0.0021
Echinococcus multilocularis ATP dependent DNA helicase Q5 0.0172 0.0404 0.0403
Brugia malayi hypothetical protein 0.0022 0.0008 0.0026
Trypanosoma brucei target of rapamycin kinase 3, putative 0.0038 0.0051 0.0284
Leishmania major DNA polymerase kappa, putative,DNA polymerase IV, putative 0.0378 0.0948 0.5556
Loa Loa (eye worm) endoplasmin 0.0147 0.0339 0.1067
Trypanosoma brucei DNA polymerase kappa, putative 0.0378 0.0948 0.555
Echinococcus multilocularis Niemann Pick C1 protein 0.0111 0.0245 0.0244
Giardia lamblia Fructose-bisphosphate aldolase 0.0978 0.2534 1
Trichomonas vaginalis conserved hypothetical protein 0.002 0.0003 0.0011
Brugia malayi mothers against decapentaplegic homolog 3 0.0032 0.0034 0.0107
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0073 0.0142 0.0817
Trypanosoma brucei DNA polymerase kappa, putative 0.0533 0.136 0.7964
Schistosoma mansoni hypothetical protein 0.0046 0.0072 0.0071
Plasmodium falciparum U4/U6.U5 tri-snRNP-associated protein 2, putative 0.0023 0.001 0.0094
Loa Loa (eye worm) cytochrome P450 family protein 0.0074 0.0145 0.0457
Mycobacterium tuberculosis Possible fatty-acid-CoA ligase FadD10 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0023 0.0011 0.0043
Toxoplasma gondii BRCA1 C Terminus (BRCT) domain-containing protein 0.0153 0.0353 0.3306
Brugia malayi STAT protein, DNA binding domain containing protein 0.0717 0.1846 0.5815
Trichomonas vaginalis flap endonuclease-1, putative 0.0024 0.0013 0.0047
Trypanosoma brucei heat shock protein 90, putative 0.0147 0.0339 0.1975
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0308 0.0765 0.0764
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0156 0.0361 0.1136
Trypanosoma brucei aurora B kinase 0.0067 0.0128 0.0734
Loa Loa (eye worm) endonuclease/Exonuclease/phosphatase 0.0021 0.0006 0.0017
Echinococcus granulosus fmrfamide receptor 0.0022 0.0008 0.0008
Onchocerca volvulus 0.0145 0.0334 0.1237
Giardia lamblia Histone acetyltransferase GCN5 0.0044 0.0068 0.0259
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0135 0.0307 0.2875
Brugia malayi hypothetical protein 0.0022 0.0008 0.0026
Trypanosoma cruzi metacaspase, putative 0.002 0.0003 0.0017
Trypanosoma brucei DNA polymerase kappa, putative 0.0308 0.0765 0.4473
Trypanosoma cruzi UEV domain/Zinc finger, C3HC4 type (RING finger), putative 0.0063 0.0117 0.0686
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.013 0.0294 0.1088
Leishmania major metacaspase, putative 0.002 0.0003 0.0017
Brugia malayi Histone deacetylase family protein 0.0094 0.0197 0.0622
Onchocerca volvulus Huntingtin homolog 0.0671 0.1723 0.6381
Echinococcus granulosus u4:u6.u5 tri snrnp associated protein 2 0.0023 0.001 0.001
Echinococcus granulosus smad 0.0071 0.0138 0.0137
Trypanosoma cruzi major cysteine proteinase, putative 0.0057 0.0101 0.0589
Toxoplasma gondii histone lysine acetyltransferase GCN5-A 0.0049 0.0078 0.0729
Trypanosoma cruzi isocitrate dehydrogenase, putative 0.0071 0.0138 0.0808
Plasmodium falciparum endoplasmin, putative 0.0104 0.0225 0.2103
Schistosoma mansoni biogenic amine (5HT) receptor 0.0022 0.0008 0.0008
Leishmania major cytochrome p450-like protein 0.0074 0.0145 0.0851
Brugia malayi hypothetical protein 0.0488 0.1239 0.3904
Trypanosoma brucei DNA-(apurinic or apyrimidinic site) lyase, putative 0.0021 0.0006 0.0017
Loa Loa (eye worm) hypothetical protein 0.0022 0.0008 0.0025
Brugia malayi orphan nuclear receptor NR2E1 0.0145 0.0334 0.1053
Loa Loa (eye worm) DNA topoisomerase III 0.0068 0.013 0.041
Mycobacterium ulcerans fructose-bisphosphate aldolase 0.0478 0.1212 0.5174
Schistosoma mansoni endoplasmin 0.0147 0.0339 0.0339
Trypanosoma cruzi ribonuclease H1, putative 0.0027 0.002 0.0118
Brugia malayi jmjC domain containing protein 0.0045 0.0068 0.0215
Echinococcus granulosus ETS domain containing protein Elk 1 0.0058 0.0104 0.0104
Echinococcus multilocularis tyrosine protein kinase Srms 0.0053 0.0091 0.009
Trichomonas vaginalis flap endonuclease-1, putative 0.0024 0.0013 0.0047
Schistosoma mansoni patched 1 0.0048 0.0076 0.0076
Trichomonas vaginalis PIKK family atypical protein kinase 0.0048 0.0077 0.0284
Trypanosoma brucei histone deacetylase, putative 0.0094 0.0197 0.1143
Brugia malayi Pax transcription factor protein 2 0.0813 0.2098 0.6608
Schistosoma mansoni ferritin 0.0019 0.0001 0.0001
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0022 0.0008 0.0008
Trypanosoma cruzi DNA polymerase kappa, putative 0.0533 0.136 0.7967
Entamoeba histolytica exodeoxyribonuclease III, putative 0.0104 0.0225 0.0888
Brugia malayi neuropeptide F receptor 0.0022 0.0008 0.0026
Trichomonas vaginalis sphingomyelinase C 2 precursor, putative 0.0021 0.0006 0.0019
Leishmania major protein kinase, putative 0.0109 0.0239 0.1397
Trichomonas vaginalis PIKK family atypical protein kinase 0.0026 0.0019 0.0067
Echinococcus granulosus peptide allatostatin:somatostatin 0.0022 0.0008 0.0008
Trypanosoma cruzi heat shock protein 85, putative 0.0147 0.0339 0.1986
Echinococcus granulosus DNA topoisomerase 2 alpha 0.0423 0.1068 0.1068
Echinococcus multilocularis transcription factor Dp 1 0.0087 0.0179 0.0179
Brugia malayi RNA binding protein 0.0141 0.0323 0.1018
Loa Loa (eye worm) TAR-binding protein 0.0141 0.0323 0.1017
Trypanosoma cruzi FHA domain containing protein, putative 0.0043 0.0063 0.0364
Loa Loa (eye worm) hypothetical protein 0.0022 0.0008 0.0025
Leishmania major heat shock protein 83-1 0.0147 0.0339 0.1986
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.002 0.0003 0.0011
Echinococcus multilocularis G protein coupled 5 hydroxytryptamine receptor 0.0022 0.0008 0.0008
Trichomonas vaginalis histone deacetylase 1, 2 ,3, putative 0.0156 0.0361 0.1338
Mycobacterium tuberculosis Probable chaperone protein HtpG (heat shock protein) (HSP90 family protein) (high temperature protein G) 0.0109 0.0239 0.1015
Loa Loa (eye worm) hypothetical protein 0.0022 0.0008 0.0025
Mycobacterium tuberculosis Probable cytochrome P450 125 Cyp125 0.0035 0.0042 0.0176
Brugia malayi Matrixin family protein 0.002 0.0002 0.0008
Echinococcus multilocularis replication factor c subunit 1 0.0043 0.0063 0.0062
Loa Loa (eye worm) hypothetical protein 0.0145 0.0334 0.1052
Giardia lamblia Pyrophosphate-fructose 6-phosphate 1-phosphotransferase alpha subunit 0.0033 0.0038 0.0144
Mycobacterium tuberculosis Probable cytochrome P450 monooxygenase 142 Cyp142 0.0035 0.0042 0.0176
Toxoplasma gondii PPIC-type PPIASE domain-containing protein 0.0046 0.007 0.0655
Trypanosoma cruzi cruzipain precursor, putative 0.0073 0.0142 0.0829
Brugia malayi phosphofructokinase 0.0124 0.0277 0.0872
Entamoeba histolytica SH2-protein kinase domain containing protein 0.002 0.0003 0.001
Echinococcus granulosus transcription factor Dp 1 0.0087 0.0179 0.0179
Mycobacterium ulcerans bifunctional enzyme MbtA: salicyl-AMP ligase (SAL-AMP ligase) + salicyl-S-ACP synthetase 0.0023 0.0011 0.0043
Trypanosoma brucei histone deacetylase 2 0.0066 0.0124 0.0711
Mycobacterium tuberculosis Possible two component system response sensor kinase membrane associated PhoR 0.0043 0.0062 0.0263
Trypanosoma cruzi mitochondrial protein 99, putative 0.0021 0.0006 0.0031
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0019 0.0001 0.0002
Brugia malayi G protein-coupled receptor 0.0022 0.0008 0.0026
Loa Loa (eye worm) hypothetical protein 0.0022 0.0008 0.0025
Trypanosoma cruzi UEV domain/Zinc finger, C3HC4 type (RING finger), putative 0.0063 0.0117 0.0686
Schistosoma mansoni hypothetical protein 0.0035 0.0042 0.0042
Echinococcus multilocularis expressed protein 0.0019 0.0001 0.0001
Brugia malayi AMP-binding enzyme family protein 0.0079 0.0158 0.0497
Entamoeba histolytica protein kinase, putative 0.0035 0.0043 0.017
Schistosoma mansoni neuropeptide F-like receptor 0.0022 0.0008 0.0008
Echinococcus granulosus neuropeptide receptor 0.0022 0.0008 0.0008
Schistosoma mansoni pap-inositol-14-phosphatase 0.0021 0.0006 0.0006
Schistosoma mansoni cript-related 0.0021 0.0006 0.0005
Mycobacterium ulcerans ATP-dependent DNA helicase II UvrD2 0.0031 0.0032 0.0133
Brugia malayi Variant SH3 domain containing protein 0.0022 0.0008 0.0026
Echinococcus multilocularis phd:f box containing protein 0.0045 0.0068 0.0068
Mycobacterium ulcerans cytochrome P450 143A4 Cyp143A4 0.0035 0.0042 0.0176
Schistosoma mansoni nuclear receptor 0.0145 0.0334 0.0334
Leishmania major long-chain-fatty-acid-CoA ligase, putative 0.0023 0.0011 0.0062
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0978 0.2534 0.9384
Schistosoma mansoni nuclear hormone receptor superfamily protein-related 0.0145 0.0334 0.0334
Onchocerca volvulus Protein ultraspiracle homolog 0.0308 0.0765 0.2831
Trichomonas vaginalis adenylate and guanylate cyclases, putative 0.0106 0.0229 0.0848
Loa Loa (eye worm) matrixin family protein 0.0044 0.0066 0.0208
Loa Loa (eye worm) hypothetical protein 0.0022 0.0008 0.0025
Loa Loa (eye worm) endonuclease/Exonuclease/phosphatase 0.0021 0.0006 0.0017
Trypanosoma brucei unspecified product 0.0225 0.0545 0.3182
Entamoeba histolytica ATP-binding cassette protein, putative 0.002 0.0003 0.0009
Onchocerca volvulus 0.1041 0.27 1
Echinococcus multilocularis nuclear receptor subfamily 1 group D 0.0163 0.038 0.038
Trichomonas vaginalis CAMK family protein kinase 0.0309 0.0767 0.2839
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0342 0.0854 0.0854
Trypanosoma cruzi Eukaryotic initiation factor 4A-1 0.0028 0.0024 0.0136
Toxoplasma gondii AMP-binding enzyme domain-containing protein 0.0023 0.0011 0.01
Brugia malayi Probable DNA topoisomerase II 0.0423 0.1068 0.3365
Brugia malayi hypothetical protein 0.0298 0.0739 0.2328
Trypanosoma cruzi Vps23 core domain containing protein, putative 0.0121 0.027 0.158
Entamoeba histolytica multidrug resistance protein, putative 0.002 0.0003 0.0009
Loa Loa (eye worm) hypothetical protein 0.0466 0.118 0.3718
Echinococcus granulosus neuropeptide receptor A26 0.0543 0.1385 0.1384
Schistosoma mansoni tyrosine kinase 0.009 0.0188 0.0188
Mycobacterium tuberculosis Conserved hypothetical alanine rich protein 0.0033 0.0037 0.0154
Schistosoma mansoni smad1 5 8 and 0.0071 0.0138 0.0137
Loa Loa (eye worm) hypothetical protein 0.0079 0.0158 0.0496
Toxoplasma gondii GTP-binding nuclear protein ran/tc4 0.0023 0.0011 0.0096
Loa Loa (eye worm) hypothetical protein 0.0032 0.0034 0.0106
Plasmodium falciparum basic transcription factor 3b, putative 0.0077 0.0153 0.1428
Trypanosoma brucei chrX additional, unordered contigs 0.0101 0.0218 0.1262
Brugia malayi tailless protein 0.0145 0.0334 0.1053
Echinococcus granulosus caspase 0.002 0.0003 0.0003
Brugia malayi Voltage-gated potassium channel, HERG (KCNH2)-related. C. elegans unc-103 ortholog 0.0044 0.0066 0.0207
Giardia lamblia Endonuclease/Exonuclease/phosphatase 0.0104 0.0225 0.0883
Echinococcus granulosus expressed conserved protein 0.0105 0.0227 0.0226
Loa Loa (eye worm) hypothetical protein 0.0145 0.0334 0.1052
Loa Loa (eye worm) endonuclease/Exonuclease/phosphatase 0.0021 0.0006 0.0017
Trichomonas vaginalis CMGC family protein kinase 0.0115 0.0253 0.0936
Onchocerca volvulus 0.0022 0.0008 0.003
Echinococcus multilocularis potassium voltage gated channel subfamily H 0.0044 0.0066 0.0065
Onchocerca volvulus Protein cycle homolog 0.0041 0.0058 0.0214
Plasmodium vivax hypothetical protein, conserved 0.0031 0.0032 0.0296
Trichomonas vaginalis heat shock protein, putative 0.0061 0.0112 0.0415
Loa Loa (eye worm) hypothetical protein 0.0671 0.1723 0.5428
Trichomonas vaginalis PIKK family atypical protein kinase 0.0026 0.0018 0.0067
Leishmania major ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative 0.0023 0.001 0.0059
Schistosoma mansoni rotamase 0.015 0.0346 0.0345
Chlamydia trachomatis DNA polymerase III subunit alpha 0.0227 0.0551 0.9345
Trypanosoma cruzi Lanosterol 14-alpha demethylase 0.0035 0.0042 0.0244
Echinococcus multilocularis heat shock protein 0.0147 0.0339 0.0339
Onchocerca volvulus 0.0308 0.0765 0.2831
Trypanosoma brucei ubiquitin carboxyl-terminal hydrolase, putative 0.0023 0.001 0.0045
Trypanosoma cruzi hypothetical protein, conserved 0.0043 0.0063 0.0364
Brugia malayi RNase H family protein 0.0027 0.002 0.0064
Loa Loa (eye worm) cytoplasmic intermediate filament protein 0.0048 0.0076 0.0238
Schistosoma mansoni tsg101-related 0.0315 0.0783 0.0783
Echinococcus multilocularis raf serine:threonine protein kinase 0.0048 0.0078 0.0077
Treponema pallidum DNA gyrase, subunit B (gyrB) 0.0242 0.0589 0.2322
Leishmania major heat shock protein 83-1 0.0147 0.0339 0.1986
Toxoplasma gondii ICE family protease (caspase) p20 domain-containing protein 0.002 0.0003 0.0027
Echinococcus granulosus tyrosine protein kinase Btk29A 0.0024 0.0014 0.0014
Plasmodium falciparum GTP-binding nuclear protein RAN/TC4 0.0023 0.0011 0.0096
Treponema pallidum chemotaxis histidine kinase (cheA) 0.0043 0.0062 0.0243
Onchocerca volvulus 0.0021 0.0006 0.0019
Brugia malayi AMP-binding enzyme family protein 0.0079 0.0158 0.0497
Echinococcus granulosus 7TM GPCR rhodopsin 0.0022 0.0008 0.0008
Trichomonas vaginalis PIKK family atypical protein kinase 0.0036 0.0044 0.0163
Echinococcus multilocularis pyroglutamylated rfamide peptide receptor 0.0022 0.0008 0.0008
Echinococcus multilocularis rhodopsin orphan GPCR 0.0022 0.0008 0.0008
Schistosoma mansoni hypothetical protein 0.0046 0.0072 0.0071
Trypanosoma cruzi heat shock protein 90, putative 0.0086 0.0177 0.1033
Loa Loa (eye worm) hypothetical protein 0.0022 0.0008 0.0025
Loa Loa (eye worm) neuropeptide F receptor 0.0022 0.0008 0.0025
Trichomonas vaginalis receptor histidine kinase, putative 0.0043 0.0062 0.023
Trichomonas vaginalis ap endonuclease, putative 0.0104 0.0225 0.0834
Loa Loa (eye worm) hypothetical protein 0.0021 0.0006 0.0017
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0073 0.0142 0.0817
Chlamydia trachomatis DNA gyrase subunit B 0.0219 0.0528 0.8946
Mycobacterium ulcerans cytochrome P450 189A7 Cyp189A7 0.0035 0.0042 0.0176
Loa Loa (eye worm) hypothetical protein 0.0048 0.0076 0.024
Loa Loa (eye worm) hypothetical protein 0.037 0.0927 0.292
Leishmania major heat shock protein 83-1 0.0147 0.0339 0.1986
Trichomonas vaginalis PIKK family atypical protein kinase 0.0036 0.0044 0.0163
Wolbachia endosymbiont of Brugia malayi DNA gyrase subunit A 0.0082 0.0166 0.2801
Loa Loa (eye worm) hypothetical protein 0.0024 0.0013 0.004
Echinococcus multilocularis muscleblind protein 0.0329 0.0819 0.0818
Loa Loa (eye worm) hypothetical protein 0.0097 0.0207 0.0651
Onchocerca volvulus 0.0079 0.0158 0.0583
Loa Loa (eye worm) hypothetical protein 0.0045 0.0068 0.0214
Trichomonas vaginalis endoplasmin, putative 0.0104 0.0225 0.0832
Mycobacterium ulcerans long-chain-acyl-CoA synthetase 0.0023 0.0011 0.0043
Loa Loa (eye worm) ubiquitin carboxyl-terminal hydrolase 0.0023 0.001 0.0032
Brugia malayi Melatonin receptor type 1A 0.0022 0.0008 0.0026
Schistosoma mansoni serine/threonine protein kinase 0.0048 0.0078 0.0077
Trypanosoma brucei long-chain-fatty-acid-CoA ligase, putative 0.0023 0.0011 0.0049
Plasmodium vivax histone deacetylase, putative 0.0066 0.0124 0.1157
Toxoplasma gondii Hsp90 domain-containing protein 0.0234 0.0569 0.5329
Loa Loa (eye worm) hypothetical protein 0.0047 0.0074 0.0232
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0978 0.2534 0.9384
Trypanosoma brucei DNA polymerase kappa, putative 0.0533 0.136 0.7964
Loa Loa (eye worm) ImpB/MucB/SamB family protein 0.0326 0.0812 0.2559
Brugia malayi Nuclear hormone receptor family member nhr-49 0.0308 0.0765 0.2409
Echinococcus multilocularis neuropeptide Y receptor 0.0022 0.0008 0.0008
Brugia malayi Steroid receptor seven-up type 2 0.0308 0.0765 0.2409
Trichomonas vaginalis AGC family protein kinase 0.0067 0.0128 0.0472
Schistosoma mansoni tyrosine kinase 0.0092 0.0194 0.0194
Trypanosoma brucei ATP-dependent 6-phosphofructokinase, glycosomal 0.0124 0.0277 0.161
Echinococcus multilocularis GPCR, family 2 0.0104 0.0224 0.0223
Treponema pallidum fructose-bisphosphate aldolase 0.0978 0.2534 1
Schistosoma mansoni aryl hydrocarbon receptor 0.0488 0.124 0.124
Brugia malayi hypothetical protein 0.0145 0.0334 0.1053
Schistosoma mansoni neuropeptide receptor 0.0022 0.0008 0.0008
Brugia malayi Protein kinase domain containing protein 0.0055 0.0097 0.0304
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0022 0.0008 0.0008
Chlamydia trachomatis DNA topoisomerase I 0.0113 0.0248 0.4149
Loa Loa (eye worm) PHD-finger family protein 0.0032 0.0034 0.0106
Loa Loa (eye worm) hypothetical protein 0.0308 0.0765 0.2408
Entamoeba histolytica endonuclease/exonuclease/phosphatase domain containing protein 0.0021 0.0006 0.0021
Brugia malayi Inositol monophosphatase family protein 0.0021 0.0006 0.002
Trichomonas vaginalis adenylate cyclase, type VII, putative 0.0106 0.0229 0.0848
Brugia malayi Protein kinase domain containing protein 0.002 0.0003 0.0009
Trypanosoma cruzi mitochondrial DNA polymerase beta, putative 0.0665 0.1706 1
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0022 0.0008 0.0008
Trypanosoma brucei metacaspase 0.002 0.0003 0.0003
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0022 0.0008 0.0008
Schistosoma mansoni prokaryotic DNA topoisomerase 0.0047 0.0075 0.0075
Mycobacterium ulcerans cytochrome P450 150A6 Cyp150A6 0.0035 0.0042 0.0176
Schistosoma mansoni smad1 5 8 and 0.0071 0.0138 0.0137
Toxoplasma gondii endonuclease/exonuclease/phosphatase family protein 0.0021 0.0006 0.0049
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.002 0.0003 0.0011
Onchocerca volvulus 0.0028 0.0025 0.0092
Giardia lamblia Grp94/Hsp90 0.0109 0.0239 0.0934
Brugia malayi nuclear receptor RXR 0.0163 0.038 0.1198
Leishmania major eukaryotic initiation factor 4a, putative 0.0028 0.0024 0.0136
Brugia malayi ATP-dependent DNA helicase, RecQ family protein 0.0172 0.0404 0.1272
Chlamydia trachomatis DNA ligase 0.0043 0.0063 0.0964
Brugia malayi G-protein coupled receptor 0.0022 0.0008 0.0026
Mycobacterium tuberculosis Possible two component sensor kinase 0.0043 0.0062 0.0263
Echinococcus granulosus JmjC domain containing protein 4 0.0045 0.0068 0.0068
Echinococcus multilocularis survival motor neuron protein 1 0.1049 0.2722 0.2722
Schistosoma mansoni matrix metallopeptidase-7 (M10 family) 0.002 0.0002 0.0002
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.013 0.0294 0.1722
Echinococcus multilocularis histone lysine N methyltransferase NSD3 0.0044 0.0067 0.0067
Trypanosoma cruzi tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.015 0.0346 0.2026
Toxoplasma gondii LsmAD domain-containing protein 0.0221 0.0534 0.5
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0036 0.0045 0.0165
Trypanosoma brucei heat shock protein, putative 0.0147 0.0339 0.1975
Echinococcus granulosus thyroid hormone receptor alpha 0.0145 0.0334 0.0334
Trypanosoma cruzi UEV domain/Zinc finger, C3HC4 type (RING finger), putative 0.0063 0.0117 0.0686
Echinococcus multilocularis G-protein coupled receptor, putative 0.0022 0.0008 0.0008
Echinococcus granulosus flap endonuclease 1 0.0118 0.0261 0.026
Plasmodium vivax endonuclease/exonuclease/phosphatase domain containing protein 0.0021 0.0006 0.0049
Mycobacterium tuberculosis Fatty-acid-AMP ligase FadD30 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) 0.0059 0.0105 0.0446
Leishmania major mitochondrial DNA topoisomerase II 0.0446 0.113 0.6619
Echinococcus multilocularis protein dispatched 1 0.0055 0.0094 0.0094
Loa Loa (eye worm) 5-hydroxytryptamine 2C receptor 0.0022 0.0008 0.0025
Trypanosoma cruzi mitogen activated protein kinase 2, putative 0.0115 0.0253 0.1481
Trypanosoma brucei heat shock protein, putative 0.0147 0.0339 0.1975
Schistosoma mansoni aryl hydrocarbon receptor nuclear translocator homolog (darnt) 0.0041 0.0058 0.0058
Plasmodium vivax multidomain scavenger receptor, putative 0.0045 0.0069 0.0639
Entamoeba histolytica endonuclease/exonuclease/phosphatase domain containing protein 0.0021 0.0006 0.0021
Schistosoma mansoni SET domain protein 0.0044 0.0067 0.0067
Treponema pallidum ATP-dependent RNA helicase 0.0028 0.0024 0.009
Brugia malayi hypothetical protein 0.0163 0.038 0.1198
Loa Loa (eye worm) MH2 domain-containing protein 0.1043 0.2706 0.8525
Loa Loa (eye worm) ubiquitin specific peptidase 39 0.0023 0.001 0.0032
Trypanosoma brucei PAB1-binding protein , putative 0.0221 0.0534 0.312
Toxoplasma gondii phosphofructokinase domain-containing protein 0.0033 0.0038 0.0356
Echinococcus granulosus histone deacetylase 1 0.0156 0.0361 0.0361
Trypanosoma brucei ingi protein (ORF1) 0.0029 0.0026 0.014
Schistosoma mansoni intermediate filament proteins 0.0089 0.0185 0.0185
Mycobacterium tuberculosis Possible cytochrome P450 126 Cyp126 0.0035 0.0042 0.0176
Echinococcus multilocularis rhodopsin orphan GPCR 0.0022 0.0008 0.0008
Echinococcus granulosus ubiquitin specific protease 41 0.013 0.0294 0.0294
Trypanosoma brucei mitochondrial DNA polymerase beta-PAK 0.0315 0.0781 0.457
Brugia malayi acetyl-Coenzyme A synthetase 2 0.0023 0.0011 0.0035
Schistosoma mansoni carbon catabolite repressor protein 0.0021 0.0006 0.0005
Entamoeba histolytica myo-inositol monophosphatase, putative 0.0204 0.0488 0.1925
Plasmodium falciparum DNA repair protein RAD2, putative 0.0024 0.0013 0.012
Echinococcus multilocularis nuclear receptor nhr 48 0.0145 0.0334 0.0334
Loa Loa (eye worm) hypothetical protein 0.002 0.0002 0.0007
Loa Loa (eye worm) fli-1 protein 0.122 0.3174 1
Leishmania major RNA-editing complex protein MP100, putative 0.0021 0.0006 0.0031
Plasmodium vivax JmjC domain containing protein 0.0045 0.0068 0.0637
Echinococcus multilocularis transfer RNA-Lys 0.0252 0.0615 0.0615
Trichomonas vaginalis PIKK family atypical protein kinase 0.0041 0.0058 0.0215
Schistosoma mansoni thyroid hormone receptor 0.0732 0.1883 0.1883
Trypanosoma brucei ubiquitin carboxyl-terminal hydrolase, putative 0.013 0.0294 0.1711
Mycobacterium tuberculosis Probable cytochrome P450 137 Cyp137 0.0035 0.0042 0.0176
Onchocerca volvulus Heat shock factor protein 2 homolog 0.0105 0.0229 0.0845
Trichomonas vaginalis guanylate cyclase, putative 0.0106 0.0229 0.0848
Brugia malayi RNA recognition motif domain containing protein 0.0141 0.0323 0.1018
Trypanosoma cruzi PAB1-binding protein , putative 0.0221 0.0534 0.3129
Trypanosoma cruzi inositol 5-phosphatase 1, putative 0.0021 0.0006 0.0031
Schistosoma mansoni Tr4/Tr2 (homologue) 0.0308 0.0765 0.0764
Loa Loa (eye worm) RNA binding protein 0.0141 0.0323 0.1017
Echinococcus multilocularis nuclear receptor subfamily 4 group A 0.0145 0.0334 0.0334
Loa Loa (eye worm) ATP-dependent DNA helicase 0.0172 0.0404 0.1271
Echinococcus granulosus eukaryotic initiation factor 4A III 0.0028 0.0024 0.0023
Mycobacterium ulcerans non-ribosomal peptide synthetase MbtF 0.0023 0.0011 0.0043
Treponema pallidum ATP-dependent DNA helicase 0.0087 0.0181 0.0712
Giardia lamblia Heat shock protein HSP 90-alpha 0.0147 0.0339 0.1332
Schistosoma mansoni smad1 5 8 and 0.0071 0.0138 0.0137
Brugia malayi GRF zinc finger family protein 0.0034 0.0041 0.0129
Echinococcus granulosus tyrosine protein kinase Fyn 0.0057 0.0102 0.0101
Leishmania major heat shock protein 83-1 0.0147 0.0339 0.1986
Echinococcus multilocularis protein patched 0.0048 0.0076 0.0076
Toxoplasma gondii endonuclease/exonuclease/phosphatase family protein 0.0021 0.0006 0.0049
Onchocerca volvulus 0.0022 0.0008 0.003
Mycobacterium tuberculosis Peptide synthetase MbtE (peptide synthase) 0.0023 0.0011 0.0043
Trypanosoma brucei heat shock protein 90, putative 0.0147 0.0339 0.1975
Onchocerca volvulus 0.0023 0.0011 0.0039
Echinococcus multilocularis Polycystic kidney disease protein 0.0045 0.0069 0.0068
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0022 0.0008 0.0008
Schistosoma mansoni blooms syndrome DNA helicase 0.0234 0.0569 0.0569
Loa Loa (eye worm) TK/INSR protein kinase 0.0055 0.0097 0.0303
Mycobacterium ulcerans cytochrome P450 142A3 Cyp142A3 0.0035 0.0042 0.0176
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0978 0.2534 0.9384
Echinococcus multilocularis Helicase RNase D C terminal, HRDC domain 0.0033 0.0037 0.0037
Loa Loa (eye worm) hypothetical protein 0.004 0.0057 0.0177
Toxoplasma gondii histone lysine methyltransferase SET1 0.031 0.077 0.7206
Brugia malayi Hemopexin family protein 0.0028 0.0024 0.0077
Brugia malayi 6-phosphofructokinase 0.0124 0.0278 0.0875
Brugia malayi Nuclear hormone receptor-like 1 0.0163 0.038 0.1198
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.002 0.0003 0.0011
Mycobacterium ulcerans inositol-monophosphatase ImpA 0.0021 0.0006 0.0024
Mycobacterium tuberculosis Probable cytochrome P450 144 Cyp144 0.0035 0.0042 0.0176
Echinococcus granulosus sterol regulatory element binding protein 0.0048 0.0076 0.0076
Loa Loa (eye worm) hypothetical protein 0.0058 0.0104 0.0327
Echinococcus granulosus Niemann Pick C1 protein 0.0111 0.0245 0.0244
Schistosoma mansoni exonuclease 0.0024 0.0013 0.0013
Leishmania major cytochrome p450-like protein 0.0035 0.0042 0.0244
Plasmodium falciparum serine/threonine protein kinase, putative 0.0067 0.0128 0.1192
Plasmodium vivax SET domain protein, putative 0.0135 0.0307 0.2875
Echinococcus multilocularis GA binding protein alpha chain 0.0402 0.1012 0.1012
Schistosoma mansoni jun-related protein 0.0309 0.0766 0.0766
Mycobacterium ulcerans acyl-CoA synthetase 0.0023 0.0011 0.0043
Schistosoma mansoni growth hormone secretagogue receptor 0.0022 0.0008 0.0008
Mycobacterium leprae putative cytochrome p450 0.0035 0.0042 0.0176
Loa Loa (eye worm) hypothetical protein 0.0104 0.0224 0.0703
Loa Loa (eye worm) hypothetical protein 0.0034 0.004 0.0126
Toxoplasma gondii histone deacetylase HDAC2 0.0156 0.0361 0.3382
Loa Loa (eye worm) hypothetical protein 0.0032 0.0034 0.0106
Loa Loa (eye worm) hypothetical protein 0.0021 0.0006 0.0019
Echinococcus granulosus expressed protein 0.0019 0.0001 0.0001
Trichomonas vaginalis carbon catabolite repressor protein, putative 0.0021 0.0006 0.0019
Onchocerca volvulus 0.0089 0.0185 0.0684
Toxoplasma gondii endonuclease/exonuclease/phosphatase family protein 0.0021 0.0006 0.0049
Loa Loa (eye worm) hypothetical protein 0.002 0.0003 0.0007
Echinococcus multilocularis deoxyribonuclease 1 2 0.0021 0.0006 0.0005
Toxoplasma gondii ATPase/histidine kinase/DNA gyrase B/HSP90 domain-containing protein 0.0043 0.0062 0.0581
Loa Loa (eye worm) hypothetical protein 0.0145 0.0334 0.1052
Echinococcus multilocularis NCK adaptor protein 0.0022 0.0008 0.0008
Schistosoma mansoni blooms syndrome DNA helicase 0.0087 0.0181 0.0181
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0145 0.0334 0.0334
Echinococcus multilocularis Pyruvate dehydrogenase (lipoamide) kinase 0.0043 0.0062 0.0062
Loa Loa (eye worm) PLK/PLK1 protein kinase 0.0623 0.1596 0.5026
Schistosoma mansoni neuropeptide F-like receptor 0.0022 0.0008 0.0008
Echinococcus granulosus GPCR family 2 0.0104 0.0224 0.0223
Brugia malayi Serotonin receptor 0.0022 0.0008 0.0026
Entamoeba histolytica tyrosyl-DNA phosphodiesterase, putative 0.015 0.0346 0.1365
Trichomonas vaginalis chromosome transmission fidelity factor, putative 0.0043 0.0063 0.023
Brugia malayi hypothetical protein 0.1049 0.2722 0.8575
Mycobacterium tuberculosis Probable sensor protein KdpD 0.0043 0.0062 0.0263
Mycobacterium tuberculosis Cytochrome P450 51 Cyp51 (CYPL1) (P450-L1A1) (sterol 14-alpha demethylase) (lanosterol 14-alpha demethylase) (P450-14DM) 0.0035 0.0042 0.0176
Echinococcus granulosus replication factor c subunit 1 0.0043 0.0063 0.0062
Brugia malayi intermediate filament protein 0.0089 0.0185 0.0583
Trichomonas vaginalis DNA helicase recq1, putative 0.0322 0.08 0.2963
Trypanosoma brucei heat shock protein, putative 0.0147 0.0339 0.1975
Echinococcus multilocularis somatostatin receptor 0.0022 0.0008 0.0008
Leishmania major cathepsin L-like protease 0.0073 0.0142 0.0829
Trichomonas vaginalis ocrl type II inositol 5-phosphatase, putative 0.0021 0.0006 0.0019
Entamoeba histolytica tumor susceptibility gene 101 protein, putative 0.0257 0.063 0.2487
Echinococcus multilocularis histone deacetylase 8 0.0066 0.0124 0.0124
Schistosoma mansoni histone deacetylase 4 5 0.0094 0.0197 0.0197
Echinococcus granulosus GTP binding nuclear protein Ran 0.0023 0.0011 0.001
Loa Loa (eye worm) G-protein coupled receptor 0.0022 0.0008 0.0025
Entamoeba histolytica peptidyl-prolyl cis-trans isomerase, putative 0.0146 0.0336 0.1326
Brugia malayi ORL1-like opioid receptor 0.0022 0.0008 0.0026
Brugia malayi hypothetical protein 0.036 0.0901 0.284
Trypanosoma cruzi mitochondrial DNA topoisomerase II, putative 0.0446 0.113 0.6619
Brugia malayi hypothetical protein 0.0041 0.006 0.0187
Trichomonas vaginalis DNA helicase recq, putative 0.0322 0.08 0.2963
Echinococcus multilocularis eukaryotic initiation factor 4A III 0.0028 0.0024 0.0023
Onchocerca volvulus 0.0022 0.0008 0.003
Trypanosoma brucei inositol/phosphatidylinositol phosphatase, putative 0.0021 0.0006 0.0017
Echinococcus multilocularis jumonji domain containing 1A 0.0045 0.0068 0.0068
Onchocerca volvulus Serine\/threonine kinase homolog 0.0623 0.1596 0.5908
Leishmania major 3-Beta-hydroxysteroid-delta(8), delta(7)-isomerase, putative 0.0157 0.0364 0.213
Schistosoma mansoni jumonji domain containing protein 0.0045 0.0068 0.0068
Brugia malayi Furin-like cysteine rich region family protein 0.0171 0.0402 0.1266
Onchocerca volvulus 0.0252 0.0617 0.2282
Schistosoma mansoni amine GPCR 0.0022 0.0008 0.0008
Echinococcus multilocularis rhodopsin orphan GPCR 0.0022 0.0008 0.0008
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0023 0.001 0.0033
Schistosoma mansoni Smad4 0.0032 0.0034 0.0034
Schistosoma mansoni hypothetical protein 0.0224 0.0541 0.0541
Schistosoma mansoni histamine-responsive GPCR (AAF21638) 0.0022 0.0008 0.0008
Echinococcus multilocularis rho GTPase activating protein 20 0.0068 0.013 0.013
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.0308 0.0765 0.2408
Echinococcus granulosus neuropeptide FF receptor 2 0.0022 0.0008 0.0008
Echinococcus multilocularis retinoic acid receptor rxr beta a retinoic acid receptor rxr alpha a retinoic acid receptor rxr alpha 0.0257 0.0629 0.0629
Echinococcus granulosus 7tm_1 domain containing protein 0.0022 0.0008 0.0008
Leishmania major DNA topoisomerase 1A 0.0068 0.013 0.0762
Mycobacterium tuberculosis Possible fatty-acid-CoA ligase FadD1 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0023 0.0011 0.0043
Mycobacterium ulcerans two component sensor kinase MprB 0.0043 0.0062 0.0263
Leishmania major flap endonuclease-1 (FEN-1), putative 0.0118 0.0261 0.1526
Loa Loa (eye worm) hypothetical protein 0.0066 0.0124 0.0389
Trypanosoma cruzi mitochondrial protein 99, putative 0.0021 0.0006 0.0031
Mycobacterium ulcerans aldehyde dehydrogenase 0.0069 0.0133 0.0563
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0308 0.0765 0.0764
Toxoplasma gondii HEAT repeat-containing protein 0.0031 0.0032 0.03
Loa Loa (eye worm) hypothetical protein 0.0163 0.038 0.1197
Mycobacterium leprae PROBABLE DNA POLYMERASE III (ALPHA CHAIN) DNAE1 (DNA NUCLEOTIDYLTRANSFERASE) 0.0228 0.0554 0.2362
Plasmodium vivax RNA helicase-1, putative 0.0028 0.0024 0.0217
Schistosoma mansoni tyrosine kinase 0.0055 0.0097 0.0096
Schistosoma mansoni voltage-gated potassium channel 0.0047 0.0075 0.0075
Brugia malayi Nuclear hormone receptor E75 0.0145 0.0334 0.1053
Echinococcus granulosus NCK adaptor protein 0.0022 0.0008 0.0008
Trypanosoma brucei metacaspase 5, putative 0.002 0.0003 0.0003
Toxoplasma gondii histone lysine demethylase JMJC1/KDM5D/JARID1D 0.0045 0.0068 0.0637
Brugia malayi nuclear hormone receptor 0.0145 0.0334 0.1053
Brugia malayi bHLH-PAS transcription factor 0.0252 0.0615 0.1937
Loa Loa (eye worm) hypothetical protein 0.0041 0.0059 0.0185
Brugia malayi MH1 domain containing protein 0.0071 0.0138 0.0434
Echinococcus granulosus ATP dependent DNA helicase Q5 0.0172 0.0404 0.0403
Loa Loa (eye worm) hypothetical protein 0.0236 0.0573 0.1805
Mycobacterium leprae Probable two component sensor kinase MprB 0.0043 0.0062 0.0263
Entamoeba histolytica recQ family helicase, putative 0.0203 0.0486 0.1916
Trichomonas vaginalis conserved hypothetical protein 0.0036 0.0045 0.0165
Mycobacterium ulcerans acyl-CoA synthetase 0.0023 0.0011 0.0043
Echinococcus granulosus serine:threonine protein kinase 12 B 0.0067 0.0128 0.0127
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.0104 0.0225 0.0709
Onchocerca volvulus 0.0167 0.039 0.1444
Loa Loa (eye worm) hypothetical protein 0.0145 0.0334 0.1052
Trichomonas vaginalis flap endonuclease-1, putative 0.0118 0.0261 0.0964
Loa Loa (eye worm) hypothetical protein 0.0059 0.0105 0.033
Giardia lamblia GTOR 0.0048 0.0077 0.0296
Echinococcus granulosus rhodopsin orphan GPCR 0.0022 0.0008 0.0008
Loa Loa (eye worm) hypothetical protein 0.0019 0.0001 0.0003
Schistosoma mansoni synaptojanin 0.0021 0.0006 0.0005
Brugia malayi Pin1-type peptidyl-prolyl cis-trans isomerase, BmPin1 0.015 0.0346 0.1089
Plasmodium vivax ADP-dependent DNA helicase RecQ, putative 0.0207 0.0496 0.4639
Trypanosoma brucei mitogen activated protein kinase 4, putative 0.0115 0.0253 0.147
Plasmodium vivax histone deacetylase 1, putative 0.0156 0.0361 0.3382
Schistosoma mansoni tar DNA-binding protein 0.0141 0.0323 0.0323
Toxoplasma gondii histone deacetylase HDAC4 0.0066 0.0124 0.1157
Schistosoma mansoni niemann-pick C1 (NPC1) 0.0113 0.0249 0.0249
Echinococcus granulosus mitogen activated protein kinase 0.0115 0.0253 0.0253
Loa Loa (eye worm) hypothetical protein 0.0028 0.0024 0.0073
Entamoeba histolytica endonuclease/exonuclease/phosphatase family protein 0.0021 0.0006 0.0021
Brugia malayi GnHR receptor homolog 0.0022 0.0008 0.0026
Brugia malayi ATP-dependent DNA helicase, RecQ family protein 0.0172 0.0404 0.1272
Loa Loa (eye worm) hypothetical protein 0.0184 0.0437 0.1375
Schistosoma mansoni proto-oncogene tyrosine-protein kinase src 0.0024 0.0014 0.0014
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0104 0.0224 0.0223
Toxoplasma gondii hypothetical protein 0.0107 0.0233 0.2181
Toxoplasma gondii XPG N-terminal domain-containing protein 0.0024 0.0013 0.012
Leishmania major histone deacetylase, putative 0.0094 0.0197 0.1155
Brugia malayi ABC transporter transmembrane region family protein 0.002 0.0003 0.0008
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0057 0.0102 0.0101
Entamoeba histolytica Activator 1 140 kDa subunit, putative 0.0043 0.0063 0.0245
Echinococcus granulosus tyrosine protein kinase ABL1 0.002 0.0003 0.0003
Schistosoma mansoni transcription factor btf3 0.0077 0.0153 0.0152
Schistosoma mansoni family C19 non-peptidase homologue (C19 family) 0.0023 0.001 0.001
Echinococcus granulosus Polycystic kidney disease protein 0.0045 0.0069 0.0068
Leishmania major histone deacetylase, putative 0.0094 0.0197 0.1155
Onchocerca volvulus 0.0021 0.0006 0.0019
Trypanosoma cruzi peptidyl-prolyl cis-trans isomerase 0.0046 0.007 0.041
Loa Loa (eye worm) hypothetical protein 0.0022 0.0008 0.0025
Echinococcus multilocularis tyrosine protein kinase Btk29A 0.0024 0.0014 0.0014
Echinococcus multilocularis thyroid hormone receptor alpha 0.0732 0.1883 0.1883
Trichomonas vaginalis conserved hypothetical protein 0.0063 0.0117 0.0433
Brugia malayi follicle stimulating hormone receptor 0.0528 0.1346 0.4241
Trypanosoma cruzi long-chain-fatty-acid-CoA ligase, putative 0.0023 0.0011 0.0062
Leishmania major target of rapamycin kinase (TOR) kinase 3 0.0038 0.0051 0.0297
Entamoeba histolytica FKBP-rapamycin associated protein (FRAP), putative 0.0048 0.0077 0.0302
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0145 0.0334 0.1237
Schistosoma mansoni ets-related 0.0058 0.0104 0.0104
Trichomonas vaginalis DEAD box ATP-dependent RNA helicase, putative 0.0028 0.0024 0.0086
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0022 0.0008 0.0008
Entamoeba histolytica phosphofructokinase, putative 0.0124 0.0277 0.1092
Trypanosoma brucei DNA topoisomerase IA, putative 0.0068 0.013 0.075
Brugia malayi Cathepsin L-like precursor 0.0019 0 0.0001
Echinococcus granulosus lysine specific demethylase 6a 0.0045 0.0068 0.0068
Loa Loa (eye worm) hypothetical protein 0.0043 0.0063 0.0199
Trichomonas vaginalis sensory transduction histidine kinase bacterial, putative 0.0043 0.0062 0.023
Trichomonas vaginalis rotamase, putative 0.0146 0.0336 0.1244
Leishmania major 4-coumarate:coa ligase-like protein 0.0079 0.0158 0.0923
Brugia malayi hypothetical protein 0.0022 0.0008 0.0026
Trypanosoma brucei UEV domain/Zinc finger, C3HC4 type (RING finger), putative 0.0063 0.0117 0.0673
Trypanosoma cruzi endonuclease/exonuclease/phosphatase, putative 0.0021 0.0006 0.0031
Loa Loa (eye worm) TK/FER protein kinase 0.0028 0.0025 0.0078
Mycobacterium ulcerans cytochrome P450 51B1 Cyp51B1 0.0035 0.0042 0.0176
Mycobacterium tuberculosis DNA topoisomerase I TopA (omega-protein) (relaxing enzyme) (untwisting enzyme) (swivelase) (type I DNA topoisomerase) (nicking-c 0.0021 0.0005 0.0019
Leishmania major protein kinase, putative 0.0119 0.0264 0.1546
Brugia malayi Inositol monophosphatase family protein 0.0021 0.0006 0.002
Treponema pallidum diphosphate--fructose-6-phosphate 1-phosphotransferase 0.0033 0.0038 0.0148
Leishmania major hypothetical protein, conserved 0.0045 0.0068 0.0399
Schistosoma mansoni hypothetical protein 0.0046 0.0072 0.0071
Trichomonas vaginalis conserved hypothetical protein 0.0036 0.0045 0.0165
Entamoeba histolytica recQ family helicase, putative 0.0084 0.0172 0.0679
Onchocerca volvulus 0.0023 0.0011 0.0039
Echinococcus granulosus Helicase RNase D C terminal HRDC domain 0.0033 0.0037 0.0037
Schistosoma mansoni eyes absent homolog 0.0097 0.0207 0.0207
Schistosoma mansoni hypothetical protein 0.2257 0.5914 0.5913
Trichomonas vaginalis histone deacetylase 1, 2 ,3, putative 0.0156 0.0361 0.1338
Schistosoma mansoni DEAD box ATP-dependent RNA helicase 0.0028 0.0024 0.0023
Trypanosoma cruzi heat shock protein 90, putative 0.0105 0.0227 0.1327
Trypanosoma brucei exonuclease, putative 0.0024 0.0013 0.0062
Mycobacterium leprae Possible regulatory protein 0.0106 0.0229 0.0975
Trichomonas vaginalis CAMK family protein kinase 0.0623 0.1596 0.5909
Brugia malayi Nuclear hormone receptor family member nhr-1 0.0308 0.0765 0.2409
Trypanosoma cruzi JmjC domain, hydroxylase, putative 0.0045 0.0068 0.0399
Trypanosoma cruzi C-14 sterol reductase, putative 0.0103 0.0222 0.1302
Loa Loa (eye worm) heat shock protein 75 0.0066 0.0124 0.039
Giardia lamblia PHD finger protein 15 0.0032 0.0034 0.0127
Schistosoma mansoni hypothetical protein 0.0021 0.0006 0.0006
Trypanosoma brucei DNA polymerase kappa, putative 0.0533 0.136 0.7964
Leishmania major heat shock protein 83-1 0.0147 0.0339 0.1986
Entamoeba histolytica acetyltransferase, GNAT family 0.0044 0.0068 0.0265
Trichomonas vaginalis PIKK family atypical protein kinase 0.0038 0.0051 0.0187
Mycobacterium ulcerans two component sensor histidine kinase SenX3 0.0043 0.0062 0.0263
Toxoplasma gondii histone lysine demethylase JMJD6a 0.0045 0.0068 0.0637
Plasmodium vivax heat shock protein, putative 0.0234 0.0569 0.5329
Trichomonas vaginalis conserved hypothetical protein 0.002 0.0003 0.0011
Loa Loa (eye worm) hypothetical protein 0.0329 0.0819 0.2578
Mycobacterium ulcerans cytochrome P450 191A3 Cyp191A3 0.0035 0.0042 0.0176
Brugia malayi Nuclear hormone receptor family member nhr-31 0.0308 0.0765 0.2409
Leishmania major ATP-binding cassette protein subfamily C, member 2, putative 0.002 0.0003 0.0013
Plasmodium falciparum ataxin-2 like protein, putative 0.0221 0.0534 0.5
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.002 0.0003 0.0011
Giardia lamblia Ubiquitin carboxyl-terminal hydrolase 14 0.0023 0.001 0.0033
Trypanosoma brucei DNA topoisomerase II beta, putative 0.0389 0.0977 0.572
Brugia malayi hypothetical protein 0.0379 0.095 0.2994
Loa Loa (eye worm) hypothetical protein 0.013 0.0294 0.0926
Trypanosoma brucei retrotransposon hot spot protein 4 (RHS4), interrupted 0.0029 0.0026 0.014
Loa Loa (eye worm) TK protein kinase 0.0035 0.0043 0.0136
Trichomonas vaginalis conserved hypothetical protein 0.002 0.0003 0.0011
Schistosoma mansoni kinase 0.0317 0.0788 0.0788
Loa Loa (eye worm) runx1 0.0063 0.0117 0.0368
Echinococcus granulosus tm gpcr rhodopsin 0.0022 0.0008 0.0008
Loa Loa (eye worm) 6-phosphofructokinase 0.0124 0.0277 0.0871
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.0978 0.2534 1
Schistosoma mansoni aminoadipate-semialdehyde dehydrogenase 0.0184 0.0436 0.0436
Brugia malayi Uncharacterized hematopoietic stem/progenitor cells protein MDS029 0.0115 0.0255 0.0802
Schistosoma mansoni histamine h1 receptor 0.0022 0.0008 0.0008
Mycobacterium tuberculosis Conserved hypothetical protein 0.0326 0.0812 0.3467
Echinococcus granulosus cytoplasmic intermediate filament protein 0.0043 0.0063 0.0063
Trichomonas vaginalis conserved hypothetical protein 0.0048 0.0076 0.0282
Brugia malayi protein-tyrosine kinase 0.0053 0.0091 0.0286
Echinococcus multilocularis neuropeptide s receptor 0.0543 0.1385 0.1384
Toxoplasma gondii XPG N-terminal domain-containing protein 0.0024 0.0013 0.012
Trichomonas vaginalis Phospholipase C precursor, putative 0.0021 0.0006 0.0019
Leishmania major sterol C-24 reductase, putative 0.0103 0.0222 0.1302
Trichomonas vaginalis glutaminase, putative 0.0602 0.154 0.5702
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0204 0.0488 0.2858
Echinococcus multilocularis L aminoadipate semialdehyde 0.0184 0.0436 0.0436
Onchocerca volvulus 0.0022 0.0008 0.003
Plasmodium vivax importin-beta 2, putative 0.0031 0.0032 0.03
Schistosoma mansoni aldehyde dehydrogenase 0.0069 0.0133 0.0132
Plasmodium vivax flap endonuclease 1, putative 0.0118 0.0261 0.2438
Echinococcus multilocularis ferritin 0.0019 0.0001 0.0001
Leishmania major pentamidine resistance protein 1 0.002 0.0003 0.0013
Toxoplasma gondii isocitrate dehydrogenase 0.0071 0.0138 0.1292
Brugia malayi Fli-1 protein 0.122 0.3174 1
Brugia malayi aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase 0.0184 0.0436 0.1374
Onchocerca volvulus 0.0022 0.0008 0.003
Loa Loa (eye worm) hypothetical protein 0.0022 0.0008 0.0025
Echinococcus granulosus rhodopsin orphan GPCR 0.0022 0.0008 0.0008
Trypanosoma cruzi ATP-dependent DEAD/H DNA helicase recQ, putative 0.0087 0.0181 0.106
Loa Loa (eye worm) hypothetical protein 0.0041 0.0059 0.0185
Plasmodium vivax acyl-CoA synthetase, putative 0.0059 0.0105 0.0982
Trypanosoma cruzi mitochondrial DNA topoisomerase II, putative 0.0446 0.113 0.6619
Onchocerca volvulus 0.0047 0.0074 0.0272
Echinococcus multilocularis Mitotic checkpoint protein PRCC, C terminal 0.0423 0.1069 0.1068
Echinococcus multilocularis Smad4 0.0071 0.0138 0.0137
Trichomonas vaginalis CAMK family protein kinase 0.0623 0.1596 0.5909
Trichomonas vaginalis flap endonuclease-1, putative 0.0024 0.0013 0.0047
Mycobacterium leprae Probable fatty-acid-CoA synthetase FadD22 (fatty-acid-CoA ligase) (fatty-acid-CoA synthase) 0.0023 0.0011 0.0043
Toxoplasma gondii ATPase/histidine kinase/DNA gyrase B/HSP90 domain-containing protein 0.0043 0.0062 0.0581
Plasmodium vivax histone deacetylase 2, putative 0.0094 0.0197 0.1845
Entamoeba histolytica protein kinase , putative 0.0067 0.0128 0.0503
Onchocerca volvulus Neuropeptide F receptor homolog 0.0022 0.0008 0.003
Trypanosoma brucei histone deacetylase 4 0.0094 0.0197 0.1143
Toxoplasma gondii CMGC kinase, MAPK family (ERK) MAPK-1 0.0115 0.0253 0.2367
Echinococcus granulosus importin subunit beta 1 0.0031 0.0032 0.0032
Loa Loa (eye worm) nucleolar RNA-associated protein alpha 0.0333 0.083 0.2612
Echinococcus multilocularis expressed protein 0.015 0.0346 0.0345
Trypanosoma cruzi sterol C-24 reductase, putative 0.0103 0.0222 0.1302
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0308 0.0765 0.2409
Echinococcus multilocularis flap endonuclease 1 0.0118 0.0261 0.026
Loa Loa (eye worm) hypothetical protein 0.0359 0.0898 0.2828
Toxoplasma gondii XPG N-terminal domain-containing protein 0.0024 0.0013 0.012
Schistosoma mansoni amine GPCR 0.0022 0.0008 0.0008
Brugia malayi hypothetical protein 0.0504 0.1282 0.4039
Trypanosoma cruzi importin beta-1 subunit, putative 0.0025 0.0017 0.0096
Mycobacterium ulcerans O-succinylbenzoic acid--CoA ligase 0.0023 0.0011 0.0043
Mycobacterium ulcerans aldehyde dehydrogenase 0.0069 0.0133 0.0563
Loa Loa (eye worm) hypothetical protein 0.0184 0.0437 0.1375
Trichomonas vaginalis conserved hypothetical protein 0.0077 0.0153 0.0565
Loa Loa (eye worm) MH2 domain-containing protein 0.0071 0.0138 0.0433
Echinococcus granulosus G protein coupled receptor 139 0.0022 0.0008 0.0008
Echinococcus granulosus mixed lineage leukemia protein mll 0.0045 0.007 0.007
Plasmodium vivax mitochondrial import inner membrane translocase subunit TIM23, putative 0.0046 0.0071 0.0664
Echinococcus multilocularis biogenic amine (5HT) receptor 0.0022 0.0008 0.0008
Schistosoma mansoni hypothetical protein 0.0022 0.0008 0.0008
Entamoeba histolytica heat shock transcription factor, putative 0.0105 0.0229 0.0901
Brugia malayi AMP-binding enzyme family protein 0.0023 0.0011 0.0035
Mycobacterium tuberculosis Probable DNA polymerase III (alpha chain) DnaE2 (DNA nucleotidyltransferase) 0.0228 0.0554 0.2362
Trypanosoma cruzi UEV domain/Zinc finger, C3HC4 type (RING finger), putative 0.0063 0.0117 0.0686
Loa Loa (eye worm) hypothetical protein 0.0045 0.0069 0.0215
Brugia malayi Isocitrate dehydrogenase 0.0071 0.0138 0.0436
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0204 0.0488 0.1806
Brugia malayi Dopamine receptor protein 2 0.0022 0.0008 0.0026
Schistosoma mansoni ferritin light chain 0.0019 0.0001 0.0001
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0073 0.0142 0.0817
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0071 0.0138 0.0138
Schistosoma mansoni adenoreceptor 0.0022 0.0008 0.0008
Trypanosoma brucei Lanosterol 14-alpha demethylase 0.0035 0.0042 0.0231
Echinococcus multilocularis growth factor receptor bound protein 2 0.0022 0.0008 0.0008
Loa Loa (eye worm) hypothetical protein 0.0163 0.038 0.1197
Brugia malayi photoreceptor-specific nuclear receptor 0.0586 0.1498 0.472
Loa Loa (eye worm) hypothetical protein 0.0067 0.0127 0.0399
Trypanosoma cruzi cysteine peptidase, clan CA, family C1, cathepsin L-like, putative 0.0066 0.0125 0.0732
Trichomonas vaginalis CAMK family protein kinase 0.0623 0.1596 0.5909
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.036 0.0901 0.0901
Trypanosoma brucei phosphatidylinositol 3-kinase tor, putative 0.0023 0.001 0.0043
Entamoeba histolytica inositol polyphosphate 5-phosphatase, putative 0.0021 0.0006 0.0021
Mycobacterium ulcerans two component sensor histidine kinase PrrB 0.0043 0.0062 0.0263
Trichomonas vaginalis conserved hypothetical protein 0.0043 0.0063 0.023
Trichomonas vaginalis histone deacetylase, putative 0.0156 0.0361 0.1338
Schistosoma mansoni tyrosine kinase 0.009 0.0188 0.0188
Trypanosoma cruzi Lanosterol 14-alpha demethylase 0.0035 0.0042 0.0244
Trypanosoma cruzi hypothetical protein, conserved 0.0101 0.0218 0.1274
Echinococcus multilocularis RUN 0.0045 0.0069 0.0068
Loa Loa (eye worm) hypothetical protein 0.0043 0.0063 0.0196
Toxoplasma gondii PHD-finger domain-containing protein 0.0032 0.0034 0.0316
Trypanosoma cruzi metacaspase 5, putative 0.002 0.0003 0.0017
Schistosoma mansoni multidrug resistance protein 0.002 0.0003 0.0002
Entamoeba histolytica acyl-coA synthetase, putative 0.0079 0.0158 0.0621
Echinococcus multilocularis cdgsh iron sulfur domain containing protein 0.0271 0.0667 0.0666
Echinococcus multilocularis insulin receptor 0.0055 0.0097 0.0096
Plasmodium vivax ATP-dependent DNA helicase Q1, putative 0.0084 0.0172 0.1611
Brugia malayi hypothetical protein 0.0045 0.0069 0.0216
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0114 0.0251 0.1469
Echinococcus multilocularis JmjC domain containing protein 4 0.0045 0.0068 0.0068
Trichomonas vaginalis adenylate and guanylate cyclases, putative 0.0106 0.0229 0.0848
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0021 0.0006 0.0022
Echinococcus multilocularis 3'(2'),5' bisphosphate nucleotidase 1 0.0021 0.0006 0.0006
Schistosoma mansoni transcription factor LCR-F1 0.036 0.0901 0.0901
Loa Loa (eye worm) hypothetical protein 0.1021 0.2648 0.8341
Echinococcus granulosus arachidonate 5 lipoxygenase 0.0197 0.0471 0.047
Brugia malayi jmjC domain containing protein 0.0045 0.0068 0.0215
Schistosoma mansoni hypothetical protein 0.0104 0.0224 0.0223
Schistosoma mansoni hypothetical protein 0.0333 0.083 0.0829
Giardia lamblia Histone deacetylase 0.0156 0.0361 0.142
Echinococcus granulosus DNA topoisomerase 3 alpha 0.0068 0.013 0.013
Loa Loa (eye worm) nuclear hormone receptor 0.0145 0.0334 0.1052
Loa Loa (eye worm) hypothetical protein 0.0145 0.0334 0.1052
Schistosoma mansoni acetyl-CoA synthetase 0.0023 0.0011 0.0011
Schistosoma mansoni nuclear hormone receptor 0.0308 0.0765 0.0764
Leishmania major isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0071 0.0138 0.0808
Brugia malayi hypothetical protein 0.0671 0.1723 0.5429
Trypanosoma brucei ribonuclease H1 0.0027 0.002 0.0105
Entamoeba histolytica pyrophosphate-dependent phosphofructokinase 0.0033 0.0038 0.015
Trypanosoma brucei acetyl-CoA synthetase, putative 0.0023 0.0011 0.0049
Echinococcus multilocularis dnaJ subfamily B 0.2257 0.5914 0.5913
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0915 0.2368 0.7459
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0156 0.0361 0.0361
Echinococcus multilocularis endoplasmin 0.0109 0.0239 0.0238
Echinococcus granulosus insulin receptor 0.0055 0.0097 0.0096
Brugia malayi transcription factor E74 isoform 0.0058 0.0104 0.0328
Mycobacterium tuberculosis Probable medium chain fatty-acid-CoA ligase FadD14 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0023 0.0011 0.0043
Schistosoma mansoni histone deacetylase hda2 0.0066 0.0124 0.0124
Loa Loa (eye worm) hypothetical protein 0.0023 0.0011 0.0034
Brugia malayi neuropeptide F receptor 0.0022 0.0008 0.0026
Mycobacterium leprae PROBABLE CHAPERONE PROTEIN HTPG (HEAT SHOCK PROTEIN) (HSP90 FAMILY PROTEIN) (HIGH TEMPERATURE PROTEIN G) 0.0109 0.0239 0.1015
Echinococcus multilocularis rhodopsin orphan GPCR 0.0022 0.0008 0.0008
Brugia malayi MH1 domain containing protein 0.0039 0.0054 0.017
Plasmodium falciparum flap endonuclease 1 0.0118 0.0261 0.2438
Echinococcus multilocularis mothers against decapentaplegic 6 0.0032 0.0034 0.0034
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0022 0.0008 0.0008
Echinococcus multilocularis fmrfamide receptor 0.0022 0.0008 0.0008
Plasmodium vivax heat shock protein 90, putative 0.0066 0.0124 0.1161
Loa Loa (eye worm) intermediate filament protein 0.0089 0.0185 0.0582
Trichomonas vaginalis replication factor C large subunit, putative 0.0043 0.0063 0.023
Schistosoma mansoni rab geranylgeranyl transferase alpha subunit 0.0326 0.0812 0.0812
Toxoplasma gondii peptidylprolyl isomerase 0.0146 0.0336 0.3146
Loa Loa (eye worm) hypothetical protein 0.0021 0.0006 0.0019
Trypanosoma cruzi heat shock protein 85, putative 0.0147 0.0339 0.1986
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0023 0.001 0.0033
Trypanosoma cruzi aurora B kinase, putative 0.0067 0.0128 0.0746
Echinococcus granulosus tyrosine protein kinase Lyn 0.0061 0.0111 0.0111
Mycobacterium ulcerans 6-phosphofructokinase 0.0124 0.0277 0.1179
Loa Loa (eye worm) hypothetical protein 0.0024 0.0013 0.004
Mycobacterium tuberculosis Probable chain -fatty-acid-CoA ligase FadD13 (fatty-acyl-CoA synthetase) 0.0079 0.0158 0.067
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.013 0.0294 0.1722
Loa Loa (eye worm) D-ets-4 DNA binding domain-containing protein 0.0058 0.0104 0.0327
Brugia malayi Nuclear hormone receptor family member nhr-14 0.0308 0.0765 0.2409
Trichomonas vaginalis AGC family protein kinase 0.0067 0.0128 0.0472
Schistosoma mansoni hypothetical protein 0.0047 0.0074 0.0074
Entamoeba histolytica Niemann-Pick C1 protein, putative 0.0111 0.0245 0.0964
Mycobacterium ulcerans hypothetical protein 0.0101 0.0218 0.0926
Schistosoma mansoni tyrosine kinase 0.0055 0.0097 0.0096
Echinococcus multilocularis terminal deoxycytidyl transferase rev1 0.0326 0.0812 0.0812
Loa Loa (eye worm) hypothetical protein 0.0022 0.0008 0.0025
Echinococcus multilocularis fmrfamide receptor 0.0022 0.0008 0.0008
Loa Loa (eye worm) steroid hormone receptor 0.0308 0.0765 0.2408
Loa Loa (eye worm) AMP-binding enzyme family protein 0.0023 0.0011 0.0034
Mycobacterium tuberculosis Monophosphatase CysQ 0.0021 0.0006 0.0024
Loa Loa (eye worm) hypothetical protein 0.0022 0.0008 0.0025
Onchocerca volvulus Mothers against decapentaplegic homolog 0.0032 0.0034 0.0124
Brugia malayi jmjC domain containing protein 0.0234 0.0568 0.1788
Loa Loa (eye worm) MH1 domain-containing protein 0.0071 0.0138 0.0433
Loa Loa (eye worm) hypothetical protein 0.0671 0.1723 0.5428
Plasmodium vivax DNA topoisomerase 3, putative 0.0068 0.013 0.1218
Onchocerca volvulus 0.0023 0.0011 0.0039
Toxoplasma gondii endonuclease/exonuclease/phosphatase family protein 0.0021 0.0006 0.0049
Brugia malayi Matrixin family protein 0.002 0.0002 0.0008
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0104 0.0224 0.0704
Leishmania major inositol/phosphatidylinositol phosphatase, putative 0.0021 0.0006 0.0031
Echinococcus multilocularis cpg binding protein 0.0167 0.0393 0.0392
Trichomonas vaginalis phosphofructokinase, putative 0.0033 0.0038 0.0141
Entamoeba histolytica hypothetical protein 0.002 0.0003 0.0009
Mycobacterium leprae Probable fructose bisphosphate aldolase Fba 0.0478 0.1212 0.5174
Echinococcus granulosus melanoma receptor tyrosine protein kinase 0.0092 0.0194 0.0194
Loa Loa (eye worm) hypothetical protein 0.0145 0.0334 0.1052
Echinococcus multilocularis heat shock protein 75 kDa, mitochondrial 0.0066 0.0124 0.0124
Onchocerca volvulus 0.0047 0.0075 0.0276
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.0308 0.0765 0.2408
Trypanosoma brucei DNA polymerase kappa, putative 0.0276 0.0681 0.3979
Leishmania major acetyl-CoA synthetase, putative 0.0023 0.0011 0.0062
Mycobacterium tuberculosis Two component sensor kinase MprB 0.0043 0.0062 0.0263
Trichomonas vaginalis conserved hypothetical protein 0.002 0.0003 0.0011
Plasmodium falciparum ADP-dependent DNA helicase RecQ 0.0291 0.0718 0.6722
Mycobacterium leprae Probable DNA topoisomerase I TopA (omega-protein) (relaxing enzyme) (untwisting enzyme) (swivelase) (type I DNA topoisomerase) ( 0.0068 0.013 0.0553
Schistosoma mansoni lipoxygenase 0.0116 0.0257 0.0257
Brugia malayi hypothetical protein 0.0041 0.006 0.0187
Echinococcus multilocularis caspase 8 0.002 0.0003 0.0003
Trichomonas vaginalis PIKK family atypical protein kinase 0.0029 0.0026 0.0094
Mycobacterium ulcerans heat shock protein 90 0.0109 0.0239 0.1015
Brugia malayi conserved hypotetical protein 0.0145 0.0334 0.1053
Mycobacterium tuberculosis Two component sensory transduction histidine kinase MtrB 0.0043 0.0062 0.0263
Schistosoma mansoni ets-related 0.122 0.3174 0.3174
Brugia malayi Endonuclease/Exonuclease/phosphatase family protein 0.0021 0.0006 0.0018
Brugia malayi Pax transcription activation domain interacting protein 0.0043 0.0063 0.0197
Leishmania major aldehyde dehydrogenase, mitochondrial precursor 0.0069 0.0133 0.0775
Trypanosoma cruzi multidrug resistance-associated protein, putative 0.002 0.0003 0.0013
Echinococcus granulosus tyrosine protein kinase Fyn 0.0057 0.0102 0.0101
Brugia malayi Serotonin receptor 0.0022 0.0008 0.0026
Brugia malayi Papain family cysteine protease containing protein 0.0019 0 0.0001
Echinococcus granulosus Basic leucine zipper bZIP transcription factor 0.038 0.0955 0.0954
Trypanosoma cruzi transcription factor btf3, putative 0.0077 0.0153 0.0894
Trichomonas vaginalis conserved hypothetical protein 0.0033 0.0037 0.0136
Loa Loa (eye worm) TK/FER protein kinase 0.002 0.0003 0.0008
Brugia malayi sulfakinin receptor protein 0.0022 0.0008 0.0026
Loa Loa (eye worm) TK/FER protein kinase 0.002 0.0003 0.0008
Echinococcus multilocularis muscleblind protein 1 0.0329 0.0819 0.0818
Mycobacterium ulcerans proteasome PrcA 0.0905 0.2342 1
Loa Loa (eye worm) CMGC/MAPK/ERK1 protein kinase 0.0115 0.0253 0.0796
Giardia lamblia Inositol 5-phosphatase 4 0.0021 0.0006 0.0014
Brugia malayi hypothetical protein 0.0047 0.0074 0.0233
Entamoeba histolytica protein kinase, putative 0.0067 0.0128 0.0503
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0022 0.0008 0.0008
Schistosoma mansoni tyrosine kinase 0.009 0.0188 0.0188
Trypanosoma cruzi PAS-domain containing phosphoglycerate kinase, putative 0.0106 0.0229 0.1342
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0308 0.0765 0.2409
Echinococcus multilocularis ETS transcription factor Elf 5 0.0058 0.0104 0.0104
Mycobacterium tuberculosis Proteasome alpha subunit PrcA; assembles with beta subunit PrcB. 0.0905 0.2342 1
Leishmania major endonuclease/exonuclease protein-like protein 0.0021 0.0006 0.0031
Onchocerca volvulus 0.0043 0.0063 0.023
Giardia lamblia Multidrug resistance-associated protein 1 0.002 0.0003 0.0003
Plasmodium falciparum histone deacetylase 2 0.0094 0.0197 0.1845
Mycobacterium tuberculosis Two component sensor histidine kinase PrrB 0.0043 0.0062 0.0263
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.0104 0.0225 0.0225
Loa Loa (eye worm) ubiquitin carboxyl-terminal hydrolase 0.0023 0.001 0.0032
Trypanosoma brucei DNA damage repair protein, putative 0.0101 0.0218 0.1262
Echinococcus multilocularis mothers against decapentaplegic 2 0.0032 0.0034 0.0034
Trypanosoma brucei DNA polymerase kappa, putative 0.0533 0.136 0.7964
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0079 0.0158 0.067
Entamoeba histolytica endonuclease/exonuclease/phosphatase family protein 0.0021 0.0006 0.0021
Loa Loa (eye worm) hypothetical protein 0.0089 0.0185 0.0583
Trypanosoma cruzi ATP-dependent DEAD/H DNA helicase recQ, putative 0.0203 0.0486 0.2844
Schistosoma mansoni cytochrome P450 0.0035 0.0042 0.0042
Entamoeba histolytica heat shock transcription factor, putative 0.0105 0.0229 0.0901
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0048 0.0077 0.0242
Trypanosoma cruzi DNA polymerase kappa, putative 0.0533 0.136 0.7967
Loa Loa (eye worm) glutaminase 2 0.0602 0.154 0.485
Schistosoma mansoni hypothetical protein 0.0032 0.0034 0.0034
Schistosoma mansoni 6-phosphofructokinase 0.0124 0.0277 0.0277
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.0308 0.0765 0.0764
Plasmodium falciparum DNA topoisomerase 2 0.0423 0.1068 1
Toxoplasma gondii flap structure-specific endonuclease 1, putative 0.0118 0.0261 0.2438
Echinococcus multilocularis serotonin receptor 0.0022 0.0008 0.0008
Schistosoma mansoni ap endonuclease 0.0104 0.0225 0.0225
Toxoplasma gondii ABC transporter transmembrane region domain-containing protein 0.002 0.0003 0.0022
Schistosoma mansoni ap endonuclease 0.0104 0.0225 0.0225
Loa Loa (eye worm) latrophilin receptor protein 2 0.0104 0.0224 0.0703
Loa Loa (eye worm) hypothetical protein 0.0022 0.0008 0.0025
Leishmania major ribonuclease H1, putative 0.0027 0.002 0.0118
Loa Loa (eye worm) hypothetical protein 0.0985 0.2554 0.8044
Trypanosoma brucei heat shock protein, putative 0.0147 0.0339 0.1975
Trypanosoma cruzi cytochrome P450, putative 0.0074 0.0145 0.0851
Trypanosoma brucei DNA topoisomerase III, putative 0.0047 0.0075 0.0424
Treponema pallidum 4'-phosphopantetheinyl transferase 0.0052 0.0087 0.0339
Trichomonas vaginalis type II inositol 5-phosphatase, putative 0.0021 0.0006 0.0019
Trypanosoma cruzi heat shock protein 85, putative 0.0105 0.0227 0.1327
Onchocerca volvulus 0.0115 0.0255 0.0942
Echinococcus granulosus growth hormone secretagogue receptor type 1 0.0022 0.0008 0.0008
Entamoeba histolytica hypothetical protein 0.036 0.0901 0.3557
Loa Loa (eye worm) hypothetical protein 0.0021 0.0006 0.0017
Echinococcus multilocularis 0.0035 0.0042 0.0042
Schistosoma mansoni retinoic acid receptor RXR 0.042 0.106 0.1059
Trypanosoma cruzi DNA topoisomerase II, putative 0.0389 0.0977 0.5726
Trypanosoma brucei hypothetical protein, conserved 0.0101 0.0218 0.1262
Echinococcus granulosus pyroglutamylated rfamide peptide receptor 0.0022 0.0008 0.0008
Brugia malayi Matrixin family protein 0.0048 0.0077 0.0242
Brugia malayi Protein kinase domain containing protein 0.002 0.0003 0.0009
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0135 0.0307 0.0307
Trichomonas vaginalis receptor histidine kinase, putative 0.0043 0.0062 0.023
Loa Loa (eye worm) hypothetical protein 0.0024 0.0014 0.0043
Echinococcus granulosus tyrosine protein kinase Srms 0.002 0.0003 0.0003
Loa Loa (eye worm) TK/FER protein kinase 0.002 0.0003 0.0008
Echinococcus granulosus aryl hydrocarbon receptor 0.0277 0.0681 0.0681
Trichomonas vaginalis CAMK family protein kinase 0.0623 0.1596 0.5909
Echinococcus granulosus inositol monophosphatase 0.0021 0.0006 0.0006
Mycobacterium tuberculosis Fatty-acid-CoA synthetase FadD17 (fatty-acid-CoA synthase) (fatty-acid-CoA ligase) 0.0023 0.0011 0.0043
Schistosoma mansoni caspase-3 (C14 family) 0.002 0.0003 0.0003
Entamoeba histolytica hypothetical protein 0.0063 0.0117 0.0462
Loa Loa (eye worm) hypothetical protein 0.0308 0.0765 0.2408
Mycobacterium tuberculosis PROBABLE FATTY-ACID-CoA LIGASE FADD18 (FRAGMENT) (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.002 0.0003 0.0007
Echinococcus multilocularis dna polymerase kappa 0.0533 0.136 0.1359
Echinococcus multilocularis Jumonji, AT rich interactive domain 1B 0.0054 0.0092 0.0092
Echinococcus multilocularis ETS transcription factor Elf 2 0.0058 0.0104 0.0104
Schistosoma mansoni hypothetical protein 0.0309 0.0766 0.0766
Toxoplasma gondii histone deacetylase HDAC5 0.0066 0.0124 0.116
Trypanosoma cruzi cytochrome P450, putative 0.0074 0.0145 0.0851
Loa Loa (eye worm) D-ets-4 DNA binding domain-containing protein 0.0402 0.1012 0.3187
Onchocerca volvulus 0.0158 0.0369 0.1364
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0156 0.0361 0.0361
Mycobacterium tuberculosis holo-[acyl-carrier protein] synthase AcpS (holo-ACP synthase) (CoA:APO-[ACP]pantetheinephosphotransferase) (CoA:APO-[acyl-carrie 0.0052 0.0087 0.0367
Schistosoma mansoni hypothetical protein 0.0046 0.0072 0.0071
Leishmania major ATP-dependent phosphofructokinase 0.0124 0.0277 0.1621
Mycobacterium ulcerans putative regultory protein 0.0043 0.0062 0.0263
Wolbachia endosymbiont of Brugia malayi 4'-phosphopantetheinyl transferase 0.0052 0.0087 0.146
Loa Loa (eye worm) hypothetical protein 0.0145 0.0334 0.1052
Echinococcus granulosus 6 phosphofructokinase 0.0124 0.0277 0.0277
Plasmodium falciparum LCCL domain-containing protein 0.0045 0.0069 0.0639
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.002 0.0003 0.0011
Trichomonas vaginalis antibiotic synthetase, putative 0.0023 0.0011 0.0039
Loa Loa (eye worm) hypothetical protein 0.0059 0.0105 0.0329
Mycobacterium tuberculosis Probable cytochrome P450 143 Cyp143 0.0035 0.0042 0.0176
Trypanosoma brucei DNA polymerase IV, putative 0.0482 0.1224 0.7167
Echinococcus granulosus ATP dependent DNA helicase Q1 0.0172 0.0404 0.0403
Brugia malayi Variant SH3 domain containing protein 0.0022 0.0008 0.0026
Mycobacterium ulcerans two component regulator - sensor kinase 0.0043 0.0062 0.0263
Toxoplasma gondii XPG N-terminal domain-containing protein 0.0024 0.0013 0.012
Trypanosoma cruzi target of rapamycin kinase 3 0.0038 0.0051 0.0297
Trypanosoma cruzi tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.015 0.0346 0.2026
Schistosoma mansoni tsg101-related 0.0315 0.0783 0.0783
Loa Loa (eye worm) DR-78 0.0145 0.0334 0.1052
Echinococcus granulosus heat shock protein 90 0.0147 0.0339 0.0339
Plasmodium falciparum replication factor C subunit 1, putative 0.0043 0.0063 0.0582
Trichomonas vaginalis conserved hypothetical protein 0.0019 0.0001 0.0002
Loa Loa (eye worm) ICD-1 protein 0.0077 0.0153 0.048
Echinococcus granulosus lysine specific demethylase 5A 0.0177 0.0418 0.0417
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0204 0.0488 0.2858
Leishmania major heat shock protein 83-1 0.0147 0.0339 0.1986
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0059 0.0105 0.0446
Schistosoma mansoni bromodomain-containing nuclear protein 1 brd1 0.0032 0.0034 0.0034
Giardia lamblia DINP protein human, muc B family 0.0378 0.0948 0.3738
Schistosoma mansoni nocturnin 0.0021 0.0006 0.0005
Loa Loa (eye worm) hypothetical protein 0.0105 0.0229 0.0719
Echinococcus granulosus allatostatin A receptor 0.0022 0.0008 0.0008
Brugia malayi Bloom's syndrome protein homolog 0.0322 0.08 0.2521
Brugia malayi Dopamine receptor protein 1, putative (partial) 0.0022 0.0008 0.0026
Echinococcus multilocularis mitogen activated protein kinase 3 0.0115 0.0253 0.0253
Brugia malayi heat shock protein 90 0.0147 0.0339 0.1068
Plasmodium vivax DNA gyrase subunit A, putative 0.0082 0.0166 0.1547
Brugia malayi DNA-binding protein D-ETS-3 0.0058 0.0104 0.0328
Plasmodium falciparum holo-[acyl-carrier-protein] synthase, putative 0.0052 0.0087 0.0809
Echinococcus granulosus rhodopsin orphan GPCR 0.0022 0.0008 0.0008
Treponema pallidum exodeoxyribonuclease (exoA) 0.0104 0.0225 0.0886
Loa Loa (eye worm) hypothetical protein 0.0059 0.0105 0.033
Onchocerca volvulus Ribonuclease H1 homolog 0.0027 0.002 0.0074
Schistosoma mansoni hypothetical protein 0.0046 0.0071 0.0071
Trichomonas vaginalis two component sensor and regulator histidine kinase bacteria, putative 0.0043 0.0062 0.023
Trypanosoma brucei Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase, putative 0.0043 0.0062 0.0351
Brugia malayi Smad1 0.0071 0.0138 0.0434
Loa Loa (eye worm) STAT protein 0.0717 0.1846 0.5814
Trichomonas vaginalis conserved hypothetical protein 0.0106 0.0229 0.0848
Brugia malayi Cell death protein 3 precursor 0.0067 0.0127 0.04
Echinococcus granulosus Ataxin 2 N terminaldomain containing protein 0.0099 0.0212 0.0212
Echinococcus granulosus lamin b receptor 0.0103 0.0222 0.0222
Schistosoma mansoni survival motor neuron protein 0.0214 0.0515 0.0515
Echinococcus granulosus tyrosine kinase|tyrosine protein kinase Fyn 0.0053 0.0091 0.009
Loa Loa (eye worm) hypothetical protein 0.0163 0.038 0.1197
Echinococcus granulosus g protein coupled receptor 0.0022 0.0008 0.0008
Echinococcus multilocularis endonuclease exonuclease phosphatase 0.0021 0.0006 0.0005
Trypanosoma cruzi apurinic/apyrimidinic endonuclease 0.0104 0.0225 0.1319
Brugia malayi histone deacetylase 3 (HD3) 0.0156 0.0361 0.1139
Brugia malayi Nuclear hormone receptor-like 1 0.0308 0.0765 0.2409
Entamoeba histolytica exonuclease, putative 0.0024 0.0013 0.005
Trypanosoma cruzi Endonuclease/Exonuclease/phosphatase family, putative 0.0021 0.0006 0.0031
Echinococcus multilocularis histone deacetylase 6 0.01 0.0214 0.0213
Echinococcus granulosus growth factor receptor bound protein 2 0.0022 0.0008 0.0008
Trichomonas vaginalis cat eye syndrome critical region protein 2, cscr2, putative 0.0049 0.0078 0.0288
Loa Loa (eye worm) hypothetical protein 0.0022 0.0008 0.0025
Echinococcus multilocularis 7TM GPCR, rhodopsin 0.0022 0.0008 0.0008
Brugia malayi AMP-binding enzyme family protein 0.0023 0.0011 0.0035
Onchocerca volvulus 0.0813 0.2098 0.7768
Echinococcus multilocularis ribonuclease H1 0.0027 0.002 0.002
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative 0.0104 0.0225 0.1307
Entamoeba histolytica serine/threonine protein kinase 6, putative 0.0067 0.0128 0.0503
Brugia malayi Histone deacetylase 1 0.0156 0.0361 0.1139
Trypanosoma cruzi ATP-dependent DEAD/H DNA helicase recQ, putative 0.0087 0.0181 0.106
Echinococcus granulosus TGF beta signal transducer SmadC 0.0071 0.0138 0.0137
Trypanosoma brucei peptidyl-prolyl cis-trans isomerase, putative 0.0046 0.007 0.0397
Schistosoma mansoni tar DNA-binding protein 0.0141 0.0323 0.0323
Plasmodium falciparum carbon catabolite repressor protein 4, putative 0.0021 0.0006 0.0049
Mycobacterium leprae POSSIBLE FATTY-ACID-CoA LIGASE FADD10 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0023 0.0011 0.0043
Entamoeba histolytica ATP-binding cassette protein, putative 0.002 0.0003 0.0009
Echinococcus multilocularis proto oncogene tyrosine protein kinase LCK 0.0057 0.0102 0.0101
Trypanosoma brucei importin beta-1 subunit, putative 0.0031 0.0032 0.0174
Mycobacterium leprae PROBABLE HYDROLASE 0.0024 0.0014 0.0056
Loa Loa (eye worm) hypothetical protein 0.0028 0.0024 0.0073
Loa Loa (eye worm) D-ets-2 protein 0.0058 0.0104 0.0327
Echinococcus granulosus Protein patched homolog 1 0.0048 0.0076 0.0076
Echinococcus granulosus dnaJ subfamily B 0.2257 0.5914 0.5913
Loa Loa (eye worm) hypothetical protein 0.0023 0.0011 0.0034
Loa Loa (eye worm) hypothetical protein 0.0059 0.0107 0.0334
Echinococcus granulosus thyrotropin releasing hormone receptor 0.0022 0.0008 0.0008
Giardia lamblia GTP-binding nuclear protein RAN/TC4 0.0023 0.0011 0.0034
Echinococcus granulosus histone lysine N methyltransferase H3 lysine 36 0.002 0.0003 0.0002
Echinococcus granulosus inositol monophosphatase 1 0.0204 0.0488 0.0488
Mycobacterium ulcerans exodeoxyribonuclease III protein XthA 0.0104 0.0225 0.0959
Echinococcus multilocularis traf and tnf receptor associated protein 0.0021 0.0006 0.0005
Toxoplasma gondii isocitrate dehydrogenase 0.0071 0.0138 0.1292
Echinococcus granulosus Niemann Pick C1 protein 0.0159 0.0371 0.0371
Trichomonas vaginalis DNA helicase recq, putative 0.0203 0.0486 0.1798
Trichomonas vaginalis heat shock protein, putative 0.0109 0.0239 0.0882
Leishmania major ATP-binding cassette protein subfamily C, member 6, putative 0.002 0.0003 0.0013
Toxoplasma gondii Acetyl-coenzyme A synthetase 2, putative 0.0023 0.0011 0.01
Echinococcus multilocularis dna polymerase eta 0.0466 0.118 0.118
Schistosoma mansoni zinc finger protein 0.0145 0.0334 0.0334
Trypanosoma brucei unspecified product 0.0225 0.0545 0.3182
Toxoplasma gondii PHD-finger domain-containing protein 0.0032 0.0034 0.0316
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.002 0.0003 0.0011
Brugia malayi hypothetical protein 0.0143 0.0327 0.1031
Brugia malayi DNA topoisomerase III beta-1 0.0047 0.0075 0.0236
Brugia malayi Nuclear hormone receptor family member nhr-3 0.0308 0.0765 0.2409
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0036 0.0045 0.0165
Loa Loa (eye worm) hypothetical protein 0.0022 0.0008 0.0025
Mycobacterium ulcerans long-chain-fatty-acid--CoA ligase 0.0079 0.0158 0.067
Trypanosoma cruzi cysteine peptidase, putative 0.0073 0.0142 0.0829
Echinococcus granulosus DNA topoisomerase 3 beta 1 0.0047 0.0075 0.0075
Loa Loa (eye worm) hypothetical protein 0.0043 0.0063 0.0196
Echinococcus granulosus multidrug resistance associated protein 1 0.002 0.0003 0.0002
Echinococcus granulosus single minded 2 0.0255 0.0625 0.0624
Trypanosoma brucei RNA editing exonuclease 2 0.0021 0.0006 0.0017
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.0308 0.0765 0.2408
Echinococcus granulosus Peptidase C19 ubiquitin carboxyl terminal hydrolase 2 0.013 0.0294 0.0294
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0315 0.0781 0.4577
Echinococcus granulosus endoplasmin 0.0109 0.0239 0.0238
Loa Loa (eye worm) voltage and ligand gated potassium channel 0.0044 0.0066 0.0206
Onchocerca volvulus 0.0214 0.0515 0.1908
Loa Loa (eye worm) hypothetical protein 0.0022 0.0008 0.0025
Trypanosoma cruzi peptidyl-prolyl cis-trans isomerase 0.0146 0.0336 0.1969
Trypanosoma brucei Endonuclease/Exonuclease/phosphatase family, putative 0.0021 0.0006 0.0017
Schistosoma mansoni cpg binding protein 0.0158 0.0369 0.0368
Brugia malayi exodeoxyribonuclease III family protein 0.0104 0.0225 0.071
Loa Loa (eye worm) inositol-1 0.0204 0.0488 0.1536
Leishmania major 4-coumarate:coa ligase-like protein 0.0079 0.0158 0.0923
Toxoplasma gondii histone lysine acetyltransferase GCN5-B 0.0049 0.0078 0.0729
Loa Loa (eye worm) hypothetical protein 0.1049 0.2722 0.8575
Onchocerca volvulus Cell death protein 3 homolog 0.0067 0.0127 0.0469
Schistosoma mansoni apoferritin-2 0.0019 0.0001 0.0001
Leishmania major phosphopantetheinyl transferase-like protein 0.0052 0.0087 0.0506
Echinococcus granulosus flap endonuclease GEN 1 0.0024 0.0013 0.0013
Echinococcus granulosus L aminoadipate semialdehyde 0.0184 0.0436 0.0436
Toxoplasma gondii DNA topoisomerase domain-containing protein 0.0092 0.0193 0.1801
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0135 0.0307 0.0307
Onchocerca volvulus 0.0022 0.0008 0.003
Trypanosoma brucei DNA topoisomerase ii 0.0446 0.113 0.6614
Trichomonas vaginalis hypothetical protein 0.0019 0.0001 0.0002
Mycobacterium tuberculosis Cytochrome P450 121 Cyp121 0.0035 0.0042 0.0176
Loa Loa (eye worm) tyrosyl-DNA phosphodiesterase 0.015 0.0346 0.1089
Schistosoma mansoni nuclear hormone receptor 0.0145 0.0334 0.0334
Leishmania major lipophosphoglycan biosynthetic protein, putative,heat shock protein 90, putative,glucose regulated protein 94, putative 0.0109 0.0239 0.1396
Trypanosoma brucei DNA polymerase kappa, putative 0.0276 0.0681 0.3979
Entamoeba histolytica endonuclease/exonuclease/phosphatase family protein 0.0021 0.0006 0.0021
Leishmania major protein kinase, putative,polo-like protein kinase, putative 0.0623 0.1596 0.9351
Trypanosoma cruzi histone deacetylase 1, putative 0.0156 0.0361 0.2117
Trypanosoma cruzi cytochrome p450-like protein, putative 0.0035 0.0042 0.0244
Loa Loa (eye worm) TYRA-2 protein 0.0022 0.0008 0.0025
Echinococcus granulosus neuropeptide Y receptor 0.0022 0.0008 0.0008
Loa Loa (eye worm) hypothetical protein 0.002 0.0002 0.0007
Trichomonas vaginalis skeletal muscle/kidney enriched inositol 5-phosphatase, putative 0.0021 0.0006 0.0019
Trypanosoma brucei DNA polymerase kappa, putative 0.0533 0.136 0.7964
Echinococcus multilocularis Aryl hydrocarbon receptor nuclear 0.0106 0.0231 0.023
Trichomonas vaginalis phosphofructokinase, putative 0.0124 0.0277 0.1024
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0071 0.0138 0.0138
Echinococcus granulosus neuropeptides capa receptor 0.0022 0.0008 0.0008
Loa Loa (eye worm) hypothetical protein 0.0163 0.038 0.1197
Echinococcus multilocularis mitochondrial import inner membrane translocase subunit TIM23, putative 0.0046 0.0071 0.0071
Trypanosoma brucei RNA helicase, putative 0.0328 0.0818 0.4786
Onchocerca volvulus 0.0022 0.0008 0.003
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0023 0.001 0.0033
Mycobacterium ulcerans acyl-CoA synthetase 0.0023 0.0011 0.0043
Brugia malayi SH2 domain containing protein 0.002 0.0003 0.0009
Trichomonas vaginalis prokaryotic DNA topoisomerase, putative 0.0068 0.013 0.0482
Schistosoma mansoni cellular tumor antigen P53 0.0167 0.039 0.039
Brugia malayi beta-NAC-like protein 0.0077 0.0153 0.0481
Trypanosoma brucei Vps23 core domain containing protein, putative 0.0121 0.027 0.1569
Echinococcus multilocularis allatostatin A receptor 0.0022 0.0008 0.0008
Plasmodium vivax hypothetical protein, conserved 0.0021 0.0006 0.0049
Loa Loa (eye worm) TK protein kinase 0.0053 0.0091 0.0285
Loa Loa (eye worm) hypothetical protein 0.0022 0.0008 0.0025
Onchocerca volvulus 0.0022 0.0008 0.003
Brugia malayi Protein kinase domain containing protein 0.002 0.0003 0.0009
Leishmania major hypothetical protein, conserved 0.0021 0.0006 0.0031
Mycobacterium ulcerans cytochrome P450 123A3 Cyp123A3 0.0035 0.0042 0.0176
Schistosoma mansoni NADP-specific isocitrate dehydrogenase 0.0071 0.0138 0.0138
Toxoplasma gondii histone deacetylase HDAC3 0.0156 0.0361 0.3382
Trypanosoma cruzi Heat shock protein 83, putative 0.0147 0.0339 0.1986
Schistosoma mansoni protein phosphatase 2C 0.0045 0.0068 0.0068
Schistosoma mansoni amine GPCR 0.0022 0.0008 0.0008
Trypanosoma brucei ATP-dependent DEAD/H DNA helicase recQ, putative 0.0203 0.0486 0.2835
Trypanosoma cruzi pantothenate kinase subunit, putative 0.0024 0.0014 0.008
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0135 0.0307 0.0307
Brugia malayi Sex muscle abnormal protein 5 0.0022 0.0008 0.0026
Echinococcus multilocularis microtubule associated protein 2 0.3803 1 1
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.002 0.0003 0.0011
Echinococcus multilocularis synaptojanin 1 0.0021 0.0006 0.0005
Schistosoma mansoni ran 0.0023 0.0011 0.001
Echinococcus multilocularis g protein coupled receptor 0.0022 0.0008 0.0008
Entamoeba histolytica hypothetical protein 0.036 0.0901 0.3557
Mycobacterium tuberculosis Probable cytochrome P450 139 Cyp139 0.0035 0.0042 0.0176
Schistosoma mansoni aldehyde dehydrogenase 0.0069 0.0133 0.0132
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.0308 0.0765 0.2408
Schistosoma mansoni chromosome transmission fidelity factor 0.0043 0.0063 0.0062
Trypanosoma cruzi UEV domain/Zinc finger, C3HC4 type (RING finger), putative 0.0063 0.0117 0.0686
Loa Loa (eye worm) hypothetical protein 0.0022 0.0008 0.0025
Brugia malayi SRC-1 0.0057 0.0102 0.032
Echinococcus multilocularis caspase 3, apoptosis cysteine peptidase 0.002 0.0003 0.0003
Loa Loa (eye worm) hypothetical protein 0.0022 0.0008 0.0025
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0135 0.0307 0.0307
Trypanosoma cruzi DNA polymerase beta thumb, putative 0.0093 0.0197 0.1152
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0327 0.0815 0.2566
Trichomonas vaginalis PIKK family atypical protein kinase 0.0036 0.0044 0.0163
Loa Loa (eye worm) hypothetical protein 0.0059 0.0105 0.033
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0022 0.0008 0.0008
Entamoeba histolytica ABC transporter, putative 0.002 0.0003 0.0009
Schistosoma mansoni apoferritin-2 0.0019 0.0001 0.0001
Echinococcus granulosus ribonuclease H1 0.0027 0.002 0.002
Brugia malayi nuclear hormone receptor family member odr-7 0.0145 0.0334 0.1053
Toxoplasma gondii UBA/TS-N domain-containing protein 0.0023 0.001 0.0094
Echinococcus multilocularis neuropeptide receptor 0.0022 0.0008 0.0008
Echinococcus granulosus 3'partial|tyrosine protein kinase Fgr 0.0057 0.0102 0.0101
Mycobacterium ulcerans cytochrome P450 187A5 Cyp187A5 0.0035 0.0042 0.0176
Schistosoma mansoni hepatocyte nuclear factor 4-alpha (hnf-4-alpha) 0.0145 0.0334 0.0334
Trichomonas vaginalis conserved hypothetical protein 0.0077 0.0153 0.0565
Echinococcus granulosus FTZ F1 alpha 0.0308 0.0765 0.0764
Mycobacterium tuberculosis Probable cytochrome P450 136 Cyp136 0.0035 0.0042 0.0176
Brugia malayi CCR4 0.0021 0.0006 0.0018
Giardia lamblia MRP-like ABC transporter 0.002 0.0003 0.0003
Plasmodium falciparum carbon catabolite repressor protein 4, putative 0.0021 0.0006 0.0049
Schistosoma mansoni RAR-like nuclear receptor 0.0308 0.0765 0.0764
Treponema pallidum DNA topoisomerase I (topA) 0.0113 0.0248 0.0976
Schistosoma mansoni hypothetical protein 0.0045 0.0069 0.0068
Treponema pallidum diphosphate--fructose-6-phosphate 1-phosphotransferase 0.0124 0.0277 0.109
Echinococcus granulosus mothers against decapentaplegic 6 0.0032 0.0034 0.0034
Leishmania major myo-inositol-1(or 4)-monophosphatase 1, putative 0.0204 0.0488 0.2858
Brugia malayi hypothetical protein 0.0022 0.0008 0.0026
Trichomonas vaginalis phosphofructokinase, putative 0.0124 0.0277 0.1024
Brugia malayi jmjC domain containing protein 0.0045 0.0068 0.0215
Echinococcus multilocularis matrix metallopeptidase 7 (M10 family) 0.0072 0.0141 0.014
Trichomonas vaginalis PIKK family atypical protein kinase 0.0031 0.0032 0.0119
Schistosoma mansoni coup transcription factor 0.0308 0.0765 0.0764
Trypanosoma cruzi 3-Beta-hydroxysteroid-delta(8), delta(7)-isomerase, putative 0.0157 0.0364 0.213
Brugia malayi Endonuclease/Exonuclease/phosphatase family protein 0.0021 0.0006 0.0018
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD5 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0056 0.0097 0.041
Loa Loa (eye worm) hypothetical protein 0.0184 0.0436 0.1373
Brugia malayi AMP-binding enzyme family protein 0.0023 0.0011 0.0035
Trichomonas vaginalis sensory transduction histidine kinase, putative 0.0043 0.0062 0.023
Mycobacterium ulcerans cytochrome P450 187A4 Cyp187A4 0.0035 0.0042 0.0176
Echinococcus multilocularis sex peptide receptor 0.0022 0.0008 0.0008
Mycobacterium ulcerans sensor kinase from two component regulatory system 0.0043 0.0062 0.0263
Echinococcus multilocularis neuropeptides capa receptor 0.0022 0.0008 0.0008
Loa Loa (eye worm) hypothetical protein 0.0059 0.0105 0.033
Echinococcus granulosus neutral sphingomyelinase 0.0021 0.0006 0.0005
Schistosoma mansoni multidrug resistance protein 0.002 0.0003 0.0002
Echinococcus multilocularis apoptotic protease activating factor 1 0.0047 0.0074 0.0074
Trypanosoma brucei DNA polymerase IV, putative 0.0533 0.136 0.7964
Echinococcus granulosus expressed protein 0.015 0.0346 0.0345
Echinococcus multilocularis snurportin 1 0.0333 0.083 0.0829
Schistosoma mansoni xp-G/rad2 DNA repair endonuclease family 0.0024 0.0013 0.0013
Onchocerca volvulus 0.0022 0.0008 0.003
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.0203 0.0487 0.4557
Schistosoma mansoni steroid hormone receptor ad4bp 0.0308 0.0765 0.0764
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0045 0.007 0.007
Mycobacterium tuberculosis Possible cytochrome P450 135A1 Cyp135A1 0.0035 0.0042 0.0176
Brugia malayi Endonuclease/Exonuclease/phosphatase family protein 0.0021 0.0006 0.0018
Trypanosoma cruzi hypothetical protein, conserved 0.0024 0.0013 0.0075
Leishmania major peptidyl-prolyl cis-trans isomerase, putative 0.0046 0.007 0.041
Echinococcus granulosus exonuclease 1 0.0024 0.0013 0.0013
Trichomonas vaginalis conserved hypothetical protein 0.0036 0.0045 0.0165
Loa Loa (eye worm) hypothetical protein 0.0039 0.0053 0.0167
Echinococcus multilocularis Pyruvate dehydrogenase (lipoamide) kinase 0.0043 0.0062 0.0062
Trichomonas vaginalis 6-phosphofructokinase, putative 0.0033 0.0038 0.0141
Brugia malayi Cathepsin L-like precursor 0.0019 0 0.0001
Echinococcus granulosus Mitotic checkpoint protein PRCC C terminal 0.0423 0.1069 0.1068
Plasmodium falciparum isocitrate dehydrogenase [NADP], mitochondrial 0.0071 0.0138 0.1292
Plasmodium falciparum phd finger protein, putative 0.0032 0.0034 0.0316
Echinococcus multilocularis g protein coupled receptor 0.0022 0.0008 0.0008
Echinococcus multilocularis atpase aaa+ type core atpase aaa type core 0.1784 0.4666 0.4666
Schistosoma mansoni thyroid hormone receptor 0.0732 0.1883 0.1883
Giardia lamblia Ribonuclease H 0.0027 0.002 0.0073
Echinococcus granulosus tm gpcr rhodopsin 0.0022 0.0008 0.0008
Echinococcus granulosus biogenic amine 5HT receptor 0.0022 0.0008 0.0008
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.0308 0.0765 0.0764
Schistosoma mansoni biogenic amine receptor 0.0022 0.0008 0.0008
Brugia malayi Endonuclease/Exonuclease/phosphatase family protein 0.0021 0.0006 0.0018
Echinococcus multilocularis acetyl coenzyme A synthetase, cytoplasmic 0.0023 0.0011 0.0011
Echinococcus granulosus GA binding protein alpha chain 0.0402 0.1012 0.1012
Schistosoma mansoni ecdysone-induced protein 78c (dr-78) 0.0163 0.038 0.038
Trichomonas vaginalis PIKK family atypical protein kinase 0.0028 0.0025 0.0092
Mycobacterium tuberculosis Conserved hypothetical protein 0.0393 0.0989 0.422
Schistosoma mansoni inositol monophosphatase 0.0204 0.0488 0.0488
Echinococcus granulosus caspase 3 apoptosis cysteine peptidase 0.002 0.0003 0.0003
Trypanosoma cruzi heat shock protein 90, putative 0.0147 0.0339 0.1986
Schistosoma mansoni pyruvate dehydrogenase 0.0043 0.0062 0.0062
Onchocerca volvulus 0.0504 0.1282 0.4747
Trypanosoma cruzi hypothetical protein, conserved 0.0024 0.0013 0.0075
Schistosoma mansoni ubiquitin-specific peptidase 44 (C19 family) 0.0023 0.001 0.001
Echinococcus granulosus peregrin 0.0046 0.0072 0.0072
Loa Loa (eye worm) GTP-binding nuclear protein RAN/TC4 0.0023 0.0011 0.0032
Onchocerca volvulus Matrix metalloproteinase homolog 0.0044 0.0066 0.0244
Trypanosoma cruzi PAS-domain containing phosphoglycerate kinase, putative 0.0106 0.0229 0.1342
Trichomonas vaginalis conserved hypothetical protein 0.0036 0.0045 0.0165
Echinococcus multilocularis histone deacetylase 6 0.0094 0.0197 0.0197
Echinococcus multilocularis neuropeptides capa receptor 0.0022 0.0008 0.0008
Mycobacterium tuberculosis Probable fructose-bisphosphate aldolase Fba 0.0478 0.1212 0.5174
Brugia malayi nuclear receptor subfamily 1, group D, member 1, putative 0.0145 0.0334 0.1053
Loa Loa (eye worm) ets-domain-containing protein 0.0058 0.0104 0.0327
Trypanosoma cruzi PAB1-binding protein , putative 0.0221 0.0534 0.3129
Brugia malayi G-protein coupled receptor 0.0022 0.0008 0.0026
Schistosoma mansoni TGF-beta signal transducer Smad2 0.0071 0.0138 0.0137
Echinococcus multilocularis g protein coupled receptor 0.0022 0.0008 0.0008
Giardia lamblia DNA topoisomerase II 0.0381 0.0956 0.3767
Toxoplasma gondii target of rapamycin (TOR), putative 0.0036 0.0044 0.0412
Loa Loa (eye worm) hypothetical protein 0.0167 0.039 0.1228
Toxoplasma gondii endonuclease/exonuclease/phosphatase family protein 0.0021 0.0006 0.0049
Brugia malayi hypothetical protein 0.0985 0.2554 0.8045
Schistosoma mansoni nuclear hormone receptor 0.0145 0.0334 0.0334
Trichomonas vaginalis histone deacetylase, putative 0.0156 0.0361 0.1338
Echinococcus granulosus epidermal growth factor receptor 0.0171 0.0402 0.0401
Mycobacterium tuberculosis Probable peptide synthetase Nrp (peptide synthase) 0.0023 0.0011 0.0043
Trichomonas vaginalis PIKK family atypical protein kinase 0.0029 0.0026 0.0094
Echinococcus granulosus ecdysone induced protein 78C 0.0308 0.0765 0.0764
Mycobacterium tuberculosis Probable cytochrome P450 141 Cyp141 0.0035 0.0042 0.0176
Echinococcus granulosus bloom syndrome protein 0.0322 0.08 0.08
Loa Loa (eye worm) hypothetical protein 0.0022 0.0008 0.0025
Entamoeba histolytica hypothetical protein 0.036 0.0901 0.3557
Schistosoma mansoni microtubule-associated protein tau 0.3803 1 1
Loa Loa (eye worm) hypothetical protein 0.021 0.0504 0.1586
Echinococcus multilocularis lipoxygenase domain containing protein 0.0045 0.0069 0.0068
Plasmodium falciparum heat shock protein 90 0.0147 0.0339 0.3172
Plasmodium falciparum ubiquitin carboxyl-terminal hydrolase 13, putative 0.0023 0.001 0.0094
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.0308 0.0765 0.0764
Mycobacterium leprae PROBABLE 6-PHOSPHOFRUCTOKINASE PFKA (PHOSPHOHEXOKINASE) (PHOSPHOFRUCTOKINASE) 0.0124 0.0277 0.1179
Brugia malayi hypothetical protein 0.0097 0.0207 0.0652
Echinococcus multilocularis musashi 0.0089 0.0185 0.0185
Brugia malayi eukaryotic initiation factor 4A 0.0028 0.0024 0.0074
Loa Loa (eye worm) heat shock protein 90 0.0147 0.0339 0.1067
Brugia malayi G protein-coupled receptor F59B2.13 0.0022 0.0008 0.0026
Schistosoma mansoni opsin-like receptor 0.0022 0.0008 0.0008
Trypanosoma cruzi peptidyl-prolyl cis-trans isomerase 0.0146 0.0336 0.1969
Mycobacterium tuberculosis Possible cytochrome P450 135B1 Cyp135B1 0.0035 0.0042 0.0176
Schistosoma mansoni muscarinic acetylcholine (GAR) receptor 0.0022 0.0008 0.0008
Onchocerca volvulus 0.0022 0.0008 0.003
Schistosoma mansoni biogenic amine (5HT) receptor 0.0022 0.0008 0.0008
Onchocerca volvulus 0.002 0.0003 0.001
Echinococcus granulosus tyrosine kinase 0.0053 0.0091 0.009
Echinococcus granulosus lipoxygenase domain containing protein 0.0045 0.0069 0.0068
Echinococcus multilocularis geminin 0.112 0.291 0.2909
Entamoeba histolytica acyl-CoA synthetase, putative 0.0079 0.0158 0.0621
Entamoeba histolytica heat shock protein 90, putative 0.0147 0.0339 0.1337
Trypanosoma brucei peptidyl-prolyl cis-trans isomerase/rotamase, putative 0.0146 0.0336 0.1958
Trypanosoma brucei phosphatidylinositol 4-kinase, putative 0.0048 0.0077 0.0436
Echinococcus multilocularis G protein coupled receptor 139 0.0022 0.0008 0.0008
Leishmania major cytochrome p450-like protein 0.0035 0.0042 0.0244
Mycobacterium ulcerans non-ribosomal peptide synthetase MbtE 0.0023 0.0011 0.0043
Schistosoma mansoni Smad4 0.0032 0.0034 0.0034
Brugia malayi Nuclear hormone receptor family member nhr-40 0.0308 0.0765 0.2409
Echinococcus granulosus DNA repair protein complementing XP G cells 0.0024 0.0013 0.0013
Trichomonas vaginalis inositol monophosphatase, putative 0.0021 0.0006 0.0022
Brugia malayi cytochrome P450 0.0035 0.0042 0.0132
Toxoplasma gondii ubiquitin specific protease 39 isoform 2, putative 0.0023 0.001 0.0094
Entamoeba histolytica heat shock protein 90, putative 0.0147 0.0339 0.1337
Plasmodium falciparum DNA topoisomerase 3, putative 0.0068 0.013 0.1218
Mycobacterium tuberculosis P-hydroxybenzoyl-AMP ligase FadD22 0.0023 0.0011 0.0043
Echinococcus granulosus apoptotic protease activating factor 1 0.0047 0.0074 0.0074
Echinococcus multilocularis dro:myosuppressin receptor 0.0022 0.0008 0.0008
Loa Loa (eye worm) hypothetical protein 0.0359 0.0898 0.2828
Plasmodium vivax holo-[acyl-carrier-protein] synthase, putative 0.0052 0.0087 0.0809
Brugia malayi Mitochondrial import inner membrane translocase subunit Tim17 family protein 0.0046 0.0071 0.0225
Entamoeba histolytica SH2-protein kinase domain containing protein 0.0021 0.0007 0.0025
Leishmania major PAS-domain containing phosphoglycerate kinase, putative 0.0106 0.0229 0.1342
Echinococcus granulosus lipoxygenase domain containing protein 0.0045 0.0069 0.0068
Trypanosoma brucei tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.015 0.0346 0.2015
Echinococcus multilocularis ets variant gene 4 0.0058 0.0104 0.0104
Giardia lamblia Heat shock protein HSP 90-alpha 0.0105 0.0227 0.0888
Loa Loa (eye worm) hypothetical protein 0.0022 0.0008 0.0025
Mycobacterium tuberculosis Two component sensor histidine kinase DosT 0.0043 0.0062 0.0263
Leishmania major hypothetical protein, conserved 0.0221 0.0534 0.3129
Trypanosoma brucei DNA repair protein RAD2, putative 0.0024 0.0013 0.0062
Mycobacterium ulcerans two component sensor histidine kinase TrcS 0.0043 0.0062 0.0263
Trypanosoma cruzi histone deacetylase, putative 0.0066 0.0124 0.0724
Loa Loa (eye worm) hypothetical protein 0.0344 0.0858 0.2702
Echinococcus multilocularis jun protein 0.038 0.0955 0.0954
Trichomonas vaginalis histone deacetylase, putative 0.0156 0.0361 0.1338
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0156 0.0361 0.0361
Echinococcus multilocularis tyrosine protein kinase Fps85D 0.002 0.0003 0.0003
Echinococcus multilocularis nibrin 0.0043 0.0063 0.0062
Echinococcus granulosus neuropeptide Y receptor 0.0022 0.0008 0.0008
Loa Loa (eye worm) hypothetical protein 0.0145 0.0334 0.1052
Brugia malayi isocitrate dehydrogenase 0.0071 0.0138 0.0436
Loa Loa (eye worm) G-protein-linked acetylcholine receptor protein 2 0.0022 0.0008 0.0025
Mycobacterium ulcerans aldehyde dehydrogenase 0.0069 0.0133 0.0563
Loa Loa (eye worm) hypothetical protein 0.0021 0.0006 0.0017
Trypanosoma cruzi DNA polymerase eta, putative 0.0241 0.0586 0.3431
Mycobacterium ulcerans DNA gyrase subunit A 0.0082 0.0166 0.0704
Schistosoma mansoni peptide (allatostatin)-like receptor 0.0022 0.0008 0.0008
Mycobacterium tuberculosis Peptide synthetase MbtF (peptide synthase) 0.0023 0.0011 0.0043
Plasmodium vivax hypothetical protein, conserved 0.002 0.0003 0.0025
Echinococcus granulosus ETS transcription factor Elf 1 0.0058 0.0104 0.0104
Echinococcus multilocularis FTZ F1 alpha 0.0308 0.0765 0.0764
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0022 0.0008 0.0008
Leishmania major heat shock protein 83-1 0.0147 0.0339 0.1986
Brugia malayi Nuclear hormone receptor family member nhr-41 0.0308 0.0765 0.2409
Mycobacterium ulcerans two component system membrane associated sensor kinase 0.0043 0.0062 0.0263
Treponema pallidum heat shock protein 90 0.0109 0.0239 0.0938
Echinococcus multilocularis ubiquitin specific protease 41 0.013 0.0294 0.0294
Echinococcus granulosus mothers against decapentaplegic 2 0.0032 0.0034 0.0034
Echinococcus multilocularis tyrosine protein kinase Src64B 0.0057 0.0102 0.0101
Onchocerca volvulus 0.002 0.0002 0.0008
Mycobacterium leprae probable proteasome (alpha subunit) PrcA 0.0905 0.2342 1
Leishmania major mitogen activated protein kinase 4, putative;with=GeneDB:LmxM19.1440 0.0115 0.0253 0.1481
Echinococcus granulosus g protein coupled receptor 0.0022 0.0008 0.0008
Treponema pallidum hypothetical protein 0.0021 0.0006 0.0019
Toxoplasma gondii propionate-CoA ligase 0.0023 0.0011 0.01
Schistosoma mansoni inositol monophosphatase 0.0204 0.0488 0.0488
Echinococcus granulosus terminal deoxycytidyl transferase rev1 0.0326 0.0812 0.0812
Trichomonas vaginalis PIKK family atypical protein kinase 0.0048 0.0077 0.0284
Brugia malayi glutaminase DH11.1 0.0602 0.154 0.4851
Loa Loa (eye worm) hypothetical protein 0.0308 0.0765 0.2408
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.0023 0.0011 0.006
Trypanosoma brucei heat shock protein, putative 0.0147 0.0339 0.1975
Schistosoma mansoni neuropeptide receptor 0.0022 0.0008 0.0008
Toxoplasma gondii ATPase, AAA family protein 0.0043 0.0063 0.0582
Trichomonas vaginalis PIKK family atypical protein kinase 0.0036 0.0044 0.0163
Trichomonas vaginalis phosphofructokinase, putative 0.0033 0.0038 0.0141
Toxoplasma gondii DNA topoisomerase family protein 0.0068 0.013 0.1218
Loa Loa (eye worm) variant SH3 domain-containing protein 0.0022 0.0008 0.0025
Schistosoma mansoni topbp1 0.0043 0.0063 0.0062
Leishmania major pantothenate kinase subunit, putative 0.0024 0.0014 0.008
Mycobacterium ulcerans NAD-dependent DNA ligase LigA 0.0043 0.0063 0.0263
Mycobacterium ulcerans DNA polymerase III subunit alpha 0.0227 0.0551 0.2349
Onchocerca volvulus Matrilysin homolog 0.002 0.0002 0.0008
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.0308 0.0765 0.0764
Echinococcus multilocularis Niemann Pick C1 protein 0.0159 0.0371 0.0371
Echinococcus multilocularis thyrotropin releasing hormone receptor 0.0022 0.0008 0.0008
Mycobacterium ulcerans hydrolase 0.0024 0.0014 0.0056
Brugia malayi Ets-domain containing protein 0.0402 0.1012 0.3188
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD3 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0056 0.0097 0.041
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0308 0.0765 0.2409
Trypanosoma brucei BRCA1 C Terminus (BRCT) domain containing protein, putative 0.0043 0.0063 0.0351
Wolbachia endosymbiont of Brugia malayi membrane associated signal transduction histidine kinase 0.0043 0.0062 0.1046
Echinococcus multilocularis aurora kinase A 0.0067 0.0128 0.0127
Leishmania major C-14 sterol reductase, putative 0.0103 0.0222 0.1302
Brugia malayi Endoplasmin precursor 0.0147 0.0339 0.1068
Trichomonas vaginalis type IV inositol 5-phosphatase, putative 0.0021 0.0006 0.0019
Echinococcus granulosus intermediate filament protein 0.0089 0.0185 0.0185
Trypanosoma brucei transcription factor BTF3, putative 0.0077 0.0153 0.0881
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 5 0.0023 0.001 0.001
Toxoplasma gondii 4'-phosphopantetheinyl transferase superfamily protein 0.0052 0.0087 0.0809
Mycobacterium tuberculosis DNA gyrase (subunit B) GyrB (DNA topoisomerase (ATP-hydrolysing)) (DNA topoisomerase II) (type II DNA topoisomerase) 0.0242 0.0589 0.2512
Plasmodium vivax 6-phosphofructokinase, putative 0.0033 0.0038 0.0356
Trichomonas vaginalis conserved hypothetical protein 0.0043 0.0063 0.023
Echinococcus granulosus dro:myosuppressin receptor 0.0022 0.0008 0.0008
Leishmania major hypothetical protein, conserved 0.0043 0.0062 0.0364
Brugia malayi serine/threonine-protein kinase 6 0.0067 0.0128 0.0402
Echinococcus multilocularis tyrosine protein kinase Src42A 0.0057 0.0102 0.0101
Entamoeba histolytica DNA topoisomerase II, putative 0.0423 0.1068 0.4215
Schistosoma mansoni hypothetical protein 0.036 0.0901 0.0901
Leishmania major hypothetical protein, conserved 0.0157 0.0364 0.213
Chlamydia trachomatis acylglycerophosphoethanolamine acyltransferase 0.0059 0.0105 0.1697
Brugia malayi hypothetical protein 0.0022 0.0008 0.0026
Echinococcus multilocularis rhodopsin orphan GPCR 0.0022 0.0008 0.0008
Mycobacterium ulcerans phenyloxazoline synthase MbtB 0.0023 0.0011 0.0043
Echinococcus multilocularis expressed conserved protein 0.0105 0.0227 0.0226
Echinococcus granulosus rhodopsin orphan GPCR 0.0022 0.0008 0.0008
Brugia malayi AMP-binding enzyme family protein 0.0023 0.0011 0.0035
Leishmania major protein kinase, putative 0.0067 0.0128 0.0746
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.0308 0.0765 0.0764
Schistosoma mansoni opsin-like receptor 0.0022 0.0008 0.0008
Onchocerca volvulus 0.002 0.0003 0.001
Toxoplasma gondii ATPase/histidine kinase/DNA gyrase B/HSP90 domain-containing protein 0.0242 0.0589 0.5512
Schistosoma mansoni terminal deoxycytidyl transferase 0.0326 0.0812 0.0812
Mycobacterium ulcerans error-prone DNA polymerase 0.0227 0.0551 0.2349
Echinococcus granulosus heat shock protein heat shock protein 90 alpha 0.0105 0.0227 0.0226
Leishmania major importin beta-1 subunit, putative 0.0025 0.0017 0.0096
Trichomonas vaginalis diphosphonucleoside phosphohydrolase, putative 0.0021 0.0006 0.0022
Loa Loa (eye worm) abnormal chemotaxis protein 14 0.0048 0.0076 0.024
Mycobacterium ulcerans cytochrome P450 125A7 Cyp125A7 0.0035 0.0042 0.0176
Loa Loa (eye worm) hypothetical protein 0.0022 0.0008 0.0025
Brugia malayi PHD-finger family protein 0.0032 0.0034 0.0108
Onchocerca volvulus 0.0022 0.0008 0.003
Loa Loa (eye worm) hypothetical protein 0.0308 0.0765 0.2408
Echinococcus multilocularis neuropeptide receptor A26 0.0543 0.1385 0.1384
Giardia lamblia Multidrug resistance-associated protein 1 0.002 0.0003 0.0003
Schistosoma mansoni tar DNA-binding protein 0.0141 0.0323 0.0323
Chlamydia trachomatis DNA gyrase subunit A 0.0082 0.0166 0.2733
Loa Loa (eye worm) hypothetical protein 0.0022 0.0008 0.0025
Trypanosoma brucei DNA polymerase kappa, putative 0.0276 0.0681 0.3979
Schistosoma mansoni flap endonuclease-1 0.0106 0.0231 0.0231
Loa Loa (eye worm) histone deacetylase 11 0.0066 0.0124 0.0389
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.002 0.0003 0.0011
Loa Loa (eye worm) hypothetical protein 0.0034 0.004 0.0124
Trichomonas vaginalis carbon catabolite repressor protein, putative 0.0021 0.0006 0.0019
Loa Loa (eye worm) follicle stimulating hormone receptor 0.0528 0.1346 0.424
Giardia lamblia Kinase, CMGC MAPK 0.0115 0.0253 0.0992
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0073 0.0142 0.0817
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0308 0.0765 0.0764
Entamoeba histolytica endonuclease/exonuclease/phosphatase family protein 0.0021 0.0006 0.0021
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0055 0.0095 0.0095
Leishmania major heat shock protein 83-1 0.0147 0.0339 0.1986
Echinococcus granulosus neuropeptide receptor 0.0022 0.0008 0.0008
Trypanosoma cruzi myo-inositol-1 phosphatase, putative 0.0021 0.0006 0.0035
Plasmodium falciparum conserved Plasmodium membrane protein, unknown function 0.002 0.0003 0.0025
Plasmodium falciparum eukaryotic initiation factor 4A 0.0028 0.0024 0.0217
Schistosoma mansoni myo inositol monophosphatase 0.0021 0.0006 0.0006
Loa Loa (eye worm) AUR protein kinase 0.0067 0.0128 0.0401
Loa Loa (eye worm) hypothetical protein 0.0022 0.0008 0.0025
Echinococcus multilocularis histone deacetylase 1 0.0156 0.0361 0.0361
Echinococcus multilocularis aldehyde dehydrogenase, mitochondrial 0.0069 0.0133 0.0132
Plasmodium vivax exonuclease I, putative 0.0024 0.0013 0.012
Brugia malayi GTP-binding nuclear protein RAN/TC4 0.0023 0.0011 0.0033
Echinococcus granulosus dna polymerase eta 0.0466 0.118 0.118
Echinococcus multilocularis mixed lineage leukemia protein mll 0.0045 0.007 0.007
Trypanosoma cruzi DNA topoisomerase IA, putative 0.0068 0.013 0.0762
Trichomonas vaginalis adenylate cyclase, putative 0.0106 0.0229 0.0848
Schistosoma mansoni subfamily C14A unassigned peptidase (C14 family) 0.002 0.0003 0.0003
Mycobacterium tuberculosis Probable cytochrome P450 124 Cyp124 0.0035 0.0042 0.0176
Loa Loa (eye worm) hypothetical protein 0.0022 0.0008 0.0025
Schistosoma mansoni adapter molecule crk 0.0022 0.0008 0.0008
Echinococcus granulosus multidrug resistance associated protein 7 0.002 0.0003 0.0002
Echinococcus multilocularis insulin growth factor 1 receptor beta 0.0055 0.0097 0.0096
Mycobacterium tuberculosis Probable cytochrome P450 140 Cyp140 0.0035 0.0042 0.0176
Leishmania major cathepsin L-like protease 0.0073 0.0142 0.0829
Echinococcus multilocularis neuropeptide FF receptor 2 0.0022 0.0008 0.0008
Schistosoma mansoni ferritin 0.0019 0.0001 0.0001
Schistosoma mansoni tyrosine kinase 0.0092 0.0194 0.0194
Brugia malayi DNA topoisomerase III 0.0068 0.013 0.0411
Plasmodium falciparum ATP-dependent DNA helicase Q1 0.0172 0.0404 0.3777
Trichomonas vaginalis conserved hypothetical protein 0.0043 0.0063 0.023
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.0308 0.0765 0.0764
Schistosoma mansoni tyrosine kinase 0.0024 0.0014 0.0014
Schistosoma mansoni hypothetical protein 0.112 0.291 0.2909
Brugia malayi Matrix metalloprotease, N-terminal domain containing protein 0.0024 0.0014 0.0044
Brugia malayi serine/threonine protein kinase 6 0.0067 0.0128 0.0402
Echinococcus granulosus transcription factor btf3 0.0077 0.0153 0.0152
Brugia malayi Endonuclease/Exonuclease/phosphatase family protein 0.0021 0.0006 0.0018
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0073 0.0142 0.0817
Schistosoma mansoni tyrosine kinase 0.0024 0.0014 0.0014
Echinococcus multilocularis tyrosine protein kinase Abl 0.0024 0.0014 0.0014
Entamoeba histolytica hypothetical protein 0.0063 0.0117 0.0462
Brugia malayi Helix-loop-helix DNA-binding domain containing protein 0.0041 0.0058 0.0183
Onchocerca volvulus 0.0045 0.0069 0.0253
Trichomonas vaginalis sensor histidine kinase, putative 0.0043 0.0062 0.023
Mycobacterium tuberculosis Probable cytochrome P450 132 Cyp132 0.0035 0.0042 0.0176
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0022 0.0008 0.0008
Brugia malayi steroid hormone receptor 0.0308 0.0765 0.2409
Toxoplasma gondii DNA topoisomerase 2, putative 0.0423 0.1068 1
Loa Loa (eye worm) hypothetical protein 0.002 0.0002 0.0005
Schistosoma mansoni ran 0.0023 0.0011 0.001
Mycobacterium ulcerans monophosphatase CysQ 0.0021 0.0006 0.0024
Leishmania major GTP-binding protein, putative 0.0023 0.0011 0.006
Mycobacterium ulcerans cytochrome P450 108B4 Cyp108B4 0.0035 0.0042 0.0176
Loa Loa (eye worm) glutaminase 0.0602 0.154 0.485
Loa Loa (eye worm) hypothetical protein 0.0264 0.0647 0.2038
Trypanosoma cruzi Emopamil binding protein, putative 0.0157 0.0364 0.213
Mycobacterium tuberculosis Probable cytochrome P450 123 Cyp123 0.0035 0.0042 0.0176
Echinococcus multilocularis inositol polyphosphate 5 phosphatase OCRL 1 0.0021 0.0006 0.0005
Schistosoma mansoni elf1 0.0058 0.0104 0.0104
Loa Loa (eye worm) TK/ABL protein kinase 0.002 0.0003 0.0008
Loa Loa (eye worm) jmjC domain-containing protein 0.0045 0.0068 0.0214
Schistosoma mansoni 6-phosphofructokinase 0.0124 0.0277 0.0277
Loa Loa (eye worm) SRC-1 0.0057 0.0102 0.0319
Loa Loa (eye worm) flap endonuclease-1 0.0118 0.0261 0.082
Trichomonas vaginalis RNA polymerase II ctd phosphatase, putative 0.0043 0.0063 0.023
Echinococcus multilocularis epidermal growth factor receptor 0.0092 0.0194 0.0194
Trypanosoma brucei ubiquitin carboxyl-terminal hydrolase, putative 0.0023 0.001 0.0045
Leishmania major DNA polymerase eta, putative 0.0241 0.0586 0.3431
Schistosoma mansoni neuropeptide receptor 0.0022 0.0008 0.0008
Echinococcus multilocularis bloom syndrome protein 0.0322 0.08 0.08
Brugia malayi Calcitonin receptor-like protein seb-1 0.0327 0.0815 0.2566
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0308 0.0765 0.2409
Plasmodium falciparum metacaspase 1 0.002 0.0003 0.0027
Echinococcus multilocularis inositol monophosphatase 1 0.0204 0.0488 0.0488
Plasmodium falciparum heat shock protein 90, putative 0.0061 0.0112 0.105
Brugia malayi Endonuclease/Exonuclease/phosphatase family protein 0.0021 0.0006 0.0018
Loa Loa (eye worm) hypothetical protein 0.002 0.0002 0.0007
Echinococcus multilocularis multidrug resistance associated protein 7 0.002 0.0003 0.0002
Schistosoma mansoni neuropeptide f receptor 76f 0.0022 0.0008 0.0008
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0156 0.0361 0.0361
Echinococcus multilocularis neuropeptide receptor 0.0022 0.0008 0.0008
Echinococcus granulosus cpg binding protein 0.0167 0.0393 0.0392
Trypanosoma cruzi histone deacetylase, putative 0.0094 0.0197 0.1155
Mycobacterium ulcerans acyl-CoA synthetase 0.0023 0.0011 0.0043
Leishmania major ATP-dependent DEAD/H DNA helicase recQ, putative 0.0203 0.0486 0.2844
Trichomonas vaginalis ferritin, putative 0.0019 0.0001 0.0002
Leishmania major hypothetical protein, conserved 0.0121 0.027 0.158
Brugia malayi kinase, mitochondrial precursor 0.0043 0.0062 0.0197
Brugia malayi Cathepsin L-like precursor 0.0019 0 0.0001
Brugia malayi MAP kinase sur-1 0.0115 0.0253 0.0797
Mycobacterium tuberculosis Probable ATP-dependent DNA helicase II UvrD2 0.0031 0.0032 0.0133
Schistosoma mansoni heat shock protein 0.0066 0.0124 0.0124
Loa Loa (eye worm) hypothetical protein 0.0043 0.0063 0.0196
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0036 0.0045 0.0165
Plasmodium falciparum conserved Plasmodium protein, unknown function 0.0031 0.0032 0.0296
Schistosoma mansoni ancient conserved domain protein 2 (cyclin m2) 0.0022 0.0008 0.0008
Schistosoma mansoni tyrosine kinase 0.0057 0.0102 0.0101
Trichomonas vaginalis inositol monophosphatase, putative 0.0021 0.0006 0.0022
Schistosoma mansoni amine GPCR 0.0022 0.0008 0.0008
Schistosoma mansoni DNA helicase recq1 0.0172 0.0404 0.0403
Plasmodium falciparum DNA repair protein REV1, putative 0.0101 0.0218 0.2035
Echinococcus granulosus tyrosine protein kinase Src42A 0.0051 0.0085 0.0085
Plasmodium vivax heat shock protein 86, putative 0.0147 0.0339 0.3172
Trypanosoma brucei inositol-1,4,5-trisphosphate (IP3) 5-phosphatase, putative 0.0021 0.0006 0.0017
Entamoeba histolytica 3(2),5-bisphosphate nucleotidase, putative 0.0021 0.0006 0.0024
Leishmania major inositol polyphosphate 1-phosphatase, putative 0.0021 0.0006 0.0035
Echinococcus multilocularis arachidonate 5 lipoxygenase 0.0197 0.0471 0.047
Brugia malayi Dopamine receptor 0.0022 0.0008 0.0026
Giardia lamblia hypothetical protein 0.0021 0.0006 0.0014
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0308 0.0765 0.2409
Mycobacterium ulcerans long-chain-fatty-acid--CoA ligase 0.0023 0.0011 0.0043
Entamoeba histolytica 90 kDa heat shock protein, putative 0.0066 0.0124 0.0489
Giardia lamblia Ubiquitin carboxyl-terminal hydrolase 4 0.013 0.0294 0.1154
Echinococcus granulosus rhodopsin orphan GPCR 0.0022 0.0008 0.0008
Echinococcus multilocularis smad 0.0071 0.0138 0.0137
Schistosoma mansoni hypothetical protein 0.0328 0.0818 0.0818
Mycobacterium ulcerans extragenic suppressor protein SuhB 0.0204 0.0488 0.208
Trichomonas vaginalis phosphofructokinase, putative 0.0124 0.0277 0.1024
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0135 0.0307 0.0307
Trichomonas vaginalis conserved hypothetical protein 0.002 0.0003 0.0011
Trypanosoma cruzi ribosomal RNA processing protein 6, putative 0.0033 0.0037 0.0215
Echinococcus multilocularis ecdysone induced protein 78C 0.0308 0.0765 0.0764
Leishmania major heat shock protein 83-1 0.0147 0.0339 0.1986
Schistosoma mansoni hypothetical protein 0.0058 0.0104 0.0104
Plasmodium vivax ataxin-2 like protein, putative 0.0221 0.0534 0.5
Plasmodium vivax hypothetical protein, conserved 0.002 0.0003 0.0027
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 8 0.013 0.0294 0.0294
Schistosoma mansoni opsin-like receptor 0.0022 0.0008 0.0008
Loa Loa (eye worm) hypothetical protein 0.002 0.0003 0.0009
Echinococcus multilocularis neutral sphingomyelinase 0.0021 0.0006 0.0005
Brugia malayi CHE-14 protein 0.0048 0.0076 0.0241
Mycobacterium tuberculosis Probable isocitrate dehydrogenase [NADP] Icd1 (oxalosuccinate decarboxylase) (IDH) (NADP+-specific ICDH) (IDP) 0.0071 0.0138 0.0587
Schistosoma mansoni DNA helicase recq5 0.0172 0.0404 0.0403
Onchocerca volvulus 0.0184 0.0436 0.1614
Trypanosoma cruzi DNA topoisomerase II, putative 0.0389 0.0977 0.5726
Mycobacterium leprae Probable UDP-galactopyranose mutase Glf (UDP-galp mutase) (NAD+-flavin adenine dinucleotide-requiring enzyme) 0.0645 0.1654 0.7062
Schistosoma mansoni ferritin 0.0019 0.0001 0.0001
Loa Loa (eye worm) hypothetical protein 0.0488 0.1239 0.3904
Schistosoma mansoni biogenic amine receptor 0.0022 0.0008 0.0008
Loa Loa (eye worm) hypothetical protein 0.0504 0.1282 0.4038
Schistosoma mansoni protein kinase 0.0067 0.0128 0.0127
Giardia lamblia Replication factor C, subunit 1 0.0043 0.0063 0.0239
Giardia lamblia ABC transporter, putative 0.002 0.0003 0.0003
Trypanosoma brucei hypothetical protein, conserved 0.0052 0.0087 0.0494
Trypanosoma cruzi hypothetical protein, conserved 0.0043 0.0063 0.0364
Loa Loa (eye worm) hypothetical protein 0.0265 0.0649 0.2044
Giardia lamblia Aurora kinase 0.0067 0.0128 0.0497
Echinococcus multilocularis serine:threonine protein kinase 12 B 0.0067 0.0128 0.0127
Echinococcus multilocularis tyrosyl DNA phosphodiesterase 1 0.015 0.0346 0.0346
Schistosoma mansoni neuropeptide receptor 0.0022 0.0008 0.0008
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.013 0.0294 0.0927
Loa Loa (eye worm) hypothetical protein 0.0022 0.0008 0.0025
Loa Loa (eye worm) matrixin family protein 0.0048 0.0077 0.0241
Mycobacterium tuberculosis Inositol-1-monophosphatase SuhB 0.0182 0.0432 0.1839
Loa Loa (eye worm) gonadotropin-releasing hormone receptor 2 0.0022 0.0008 0.0025
Leishmania major histone deacetylase, putative 0.0156 0.0361 0.2117
Mycobacterium ulcerans cytochrome P450 188A3 Cyp188A3 0.0035 0.0042 0.0176
Trypanosoma brucei metacaspase MCA2 0.002 0.0003 0.0003
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0145 0.0334 0.1237
Loa Loa (eye worm) hypothetical protein 0.0308 0.0765 0.2408
Brugia malayi CXXC zinc finger family protein 0.0158 0.0369 0.1162
Echinococcus multilocularis orexin receptor type 2 0.0022 0.0008 0.0008
Leishmania major inositol phosphosphingolipid phospholipase C-Like 0.0021 0.0006 0.0031
Brugia malayi multidrug resistance related protein 1 0.002 0.0003 0.0008
Plasmodium vivax DNA repair protein REV1, putative 0.0101 0.0218 0.2035
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.0172 0.0404 0.3777
Echinococcus multilocularis growth hormone secretagogue receptor type 1 0.0022 0.0008 0.0008
Brugia malayi hypothetical protein 0.0045 0.0069 0.0216
Plasmodium vivax exodeoxyribonuclease III, putative 0.0021 0.0006 0.0049
Schistosoma mansoni synaptojanin 0.0021 0.0006 0.0005
Trypanosoma brucei flap endonuclease-1 (FEN-1), putative 0.0118 0.0261 0.1515
Trypanosoma cruzi DNA repair protein RAD2, putative 0.0024 0.0013 0.0075
Entamoeba histolytica endonuclease/exonuclease/phosphatase family protein 0.0021 0.0006 0.0021
Trypanosoma cruzi Phosphatidylinositol 3-kinase tor2 0.0048 0.0077 0.0449
Leishmania major ATP-binding cassette protein subfamily C, member 1, putative 0.002 0.0003 0.0013
Leishmania major basic transcription factor 3a, putative 0.0077 0.0153 0.0894
Brugia malayi Cytochrome P450 family protein 0.0074 0.0145 0.0458
Brugia malayi TAR-binding protein 0.0141 0.0323 0.1018
Onchocerca volvulus 0.0488 0.1239 0.4589
Mycobacterium ulcerans 4'-phosphopantetheinyl transferase 0.0052 0.0087 0.0367
Trichomonas vaginalis conserved hypothetical protein 0.0043 0.0063 0.023
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0023 0.001 0.0037
Schistosoma mansoni histone deacetylase 4 5 0.0094 0.0197 0.0197
Brugia malayi MH2 domain containing protein 0.1043 0.2706 0.8525
Trichomonas vaginalis PIKK family atypical protein kinase 0.0048 0.0077 0.0284
Trypanosoma cruzi Endonuclease/Exonuclease/phosphatase family, putative 0.0021 0.0006 0.0031
Schistosoma mansoni rab6-interacting 0.0045 0.0069 0.0068
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0022 0.0008 0.0008
Echinococcus granulosus orexin receptor type 2 0.0022 0.0008 0.0008
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.0308 0.0765 0.0764
Echinococcus multilocularis DNA repair protein complementing XP G cells 0.0024 0.0013 0.0013
Echinococcus granulosus heat shock protein 90 0.0105 0.0227 0.0226
Loa Loa (eye worm) helix-loop-helix DNA-binding domain-containing protein 0.0041 0.0058 0.0182
Loa Loa (eye worm) hypothetical protein 0.0145 0.0334 0.1052
Brugia malayi hypothetical protein 0.0145 0.0334 0.1053
Trichomonas vaginalis conserved hypothetical protein 0.015 0.0346 0.1279
Brugia malayi Ets-domain containing protein 0.0402 0.1012 0.3188
Onchocerca volvulus 0.0157 0.0364 0.1346
Echinococcus granulosus g-protein coupled receptor 0.0022 0.0008 0.0008
Plasmodium vivax DNA repair protein RAD2, putative 0.0024 0.0013 0.012
Trypanosoma brucei ribosomal RNA processing protein 6 0.0033 0.0037 0.0202
Schistosoma mansoni cpg binding protein 0.0167 0.0393 0.0392
Leishmania major ATP-binding cassette protein subfamily C, member 5, putative 0.002 0.0003 0.0013
Schistosoma mansoni gcn5proteinral control of amino-acid synthesis 5-like 2 gcnl2 0.0165 0.0386 0.0386
Mycobacterium ulcerans acyl-CoA synthetase 0.0023 0.0011 0.0043
Schistosoma mansoni hypothetical protein 0.0287 0.071 0.0709
Echinococcus multilocularis lipoxygenase domain containing protein 0.0045 0.0069 0.0068
Schistosoma mansoni voltage-gated potassium channel 0.0047 0.0075 0.0075
Giardia lamblia Exonuclease 1 0.0024 0.0013 0.0044
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0073 0.0142 0.0817
Onchocerca volvulus Matrilysin homolog 0.0044 0.0066 0.0244
Trypanosoma cruzi peptidyl-prolyl cis-trans isomerase, putative 0.0046 0.007 0.041
Mycobacterium tuberculosis Probable cytochrome P450 138 Cyp138 0.0035 0.0042 0.0176
Onchocerca volvulus Huntingtin homolog 0.0671 0.1723 0.6381
Mycobacterium ulcerans cytochrome P450 126A3 Cyp126A3 0.0035 0.0042 0.0176
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0073 0.0142 0.0817
Echinococcus multilocularis eukaryotic initiation factor 4A 0.0028 0.0024 0.0023
Echinococcus granulosus histone lysine N methyltransferase NSD3 0.0044 0.0067 0.0067
Brugia malayi RNase H family protein 0.0027 0.002 0.0064
Trichomonas vaginalis conserved hypothetical protein 0.0077 0.0153 0.0565
Brugia malayi histone deacetylase 1 (HD1) 0.0156 0.0361 0.1139
Echinococcus granulosus c src tyrosine kinase 0.0024 0.0014 0.0014
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase 5, putative 0.0023 0.001 0.004
Echinococcus granulosus insulin growth factor 1 receptor beta 0.0055 0.0097 0.0096
Echinococcus granulosus jumonji domain containing 1A 0.0045 0.0068 0.0068
Echinococcus granulosus tyrosine protein kinase Blk 0.0053 0.0091 0.009
Loa Loa (eye worm) hypothetical protein 0.0145 0.0334 0.1052
Plasmodium vivax DNA gyrase subunit B, putative 0.0242 0.0589 0.5512
Schistosoma mansoni phosphoglucomutase 0.0027 0.002 0.002
Trypanosoma brucei Heat shock protein 83, putative 0.0147 0.0339 0.1975
Trypanosoma brucei inositol-1(or 4)-monophosphatase, putative 0.0021 0.0006 0.0022
Plasmodium falciparum acetyl-CoA synthetase, putative 0.0023 0.0011 0.01
Echinococcus multilocularis isocitrate dehydrogenase 0.0071 0.0138 0.0138
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.0978 0.2534 1
Echinococcus multilocularis PHD finger protein rhinoceros 0.0032 0.0034 0.0034
Echinococcus granulosus rhodopsin orphan GPCR 0.0022 0.0008 0.0008
Leishmania major DNA polymerase kappa, putative 0.0101 0.0218 0.1274
Entamoeba histolytica hypothetical protein 0.0063 0.0117 0.0462
Onchocerca volvulus 0.0022 0.0008 0.003
Brugia malayi Matrixin family protein 0.002 0.0002 0.0008
Trypanosoma cruzi Emopamil binding protein, putative 0.0157 0.0364 0.213
Trichomonas vaginalis antibiotic synthetase, putative 0.0023 0.0011 0.0039
Loa Loa (eye worm) ubiquitin carboxyl-terminal hydrolase 0.0023 0.001 0.0032
Echinococcus multilocularis lysine specific demethylase 6a 0.0045 0.0068 0.0068
Trichomonas vaginalis PIKK family atypical protein kinase 0.0038 0.0051 0.0187
Mycobacterium tuberculosis Probable two component sensor kinase 0.0043 0.0062 0.0263
Trichomonas vaginalis RNA polymerase II ctd phosphatase, putative 0.0043 0.0063 0.023
Loa Loa (eye worm) hypothetical protein 0.0022 0.0008 0.0025
Trypanosoma brucei DNA topoisomerase III, putative 0.0068 0.013 0.075
Echinococcus multilocularis peptide (allatostatin:somatostatin) 0.0022 0.0008 0.0008
Echinococcus granulosus Pyruvate dehydrogenase lipoamide kinase 0.0043 0.0062 0.0062
Schistosoma mansoni serine/threonine protein kinase 0.0067 0.0128 0.0127
Schistosoma mansoni phosphoglucomutase 0.0027 0.002 0.002
Loa Loa (eye worm) hypothetical protein 0.0046 0.0071 0.0223
Onchocerca volvulus 0.0298 0.0739 0.2735
Trypanosoma brucei DNA polymerase IV, putative 0.0533 0.136 0.7964
Entamoeba histolytica DNA-repair protein, putative 0.0024 0.0013 0.005
Loa Loa (eye worm) hypothetical protein 0.0059 0.0105 0.033
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0029 0.0026 0.0026
Mycobacterium tuberculosis Probable peptidoglycan hydrolase 0.0024 0.0014 0.0056
Trypanosoma cruzi multidrug resistance protein E, putative 0.002 0.0003 0.0013
Onchocerca volvulus 0.0135 0.0307 0.1137
Brugia malayi ecdysone receptor 0.0145 0.0334 0.1053
Toxoplasma gondii exonuclease III APE 0.0104 0.0225 0.2107
Echinococcus multilocularis DNA topoisomerase 2 alpha 0.0423 0.1068 0.1068
Schistosoma mansoni cpg binding protein 0.0167 0.0393 0.0392
Trypanosoma cruzi ribonuclease H1, putative 0.0027 0.002 0.0118
Trichomonas vaginalis CAMK family protein kinase 0.0309 0.0767 0.2839
Brugia malayi Protein kinase domain containing protein 0.002 0.0003 0.0009
Loa Loa (eye worm) hypothetical protein 0.0171 0.0401 0.1261
Loa Loa (eye worm) hypothetical protein 0.0022 0.0008 0.0025

Activities

Activity type Activity value Assay description Source Reference
Activity (binding) = 0.008 uM Inhibitory activity against human immunodeficiency virus type 1 reverse transcriptase (HIV-1 RT) ChEMBL. 12086483
Activity (binding) = 0.008 uM Inhibitory activity against human immunodeficiency virus type 1 reverse transcriptase (HIV-1 RT) ChEMBL. 12086483
CC50 (ADMET) > 3 uM Cytotoxicity against human MT4 cells assessed as induction of cell death by MTT method ChEMBL. 24933420
CC50 (functional) = 112 uM Cytotoxicity against MT-4 cells. ChEMBL. 11472208
CC50 (functional) = 112 uM Cytotoxicity against MT-4 cells. ChEMBL. 11472208
EC50 (functional) = 0.008 uM Effective concentration against HIV-1 induced cytopathogenicity in MT-4 cells ChEMBL. 11472208
ID50 (binding) = 0.003 uM Inhibition of wild type HIV-1 recombinant reverse transcriptase assessed as incorporation of [3H]dTTP into poly(rA)/oligo(dT)10:1 ChEMBL. 24933420
Selectivity index (functional) = 14000 CC50/EC50 ratio of the compound ChEMBL. 11472208

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

Bibliographic References

2 literature references were collected for this gene.

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