Detailed information for compound 1394015

Basic information

Technical information
  • TDR Targets ID: 1394015
  • Name: 2-[[5-(1,3-benzodioxol-5-yl)-1,2-oxazol-3-yl] methoxy]-N-(3,5-dimethylphenyl)acetamide
  • MW: 380.394 | Formula: C21H20N2O5
  • H donors: 1 H acceptors: 2 LogP: 3.16 Rotable bonds: 7
    Rule of 5 violations (Lipinski): 1
  • SMILES: O=C(Nc1cc(C)cc(c1)C)COCc1noc(c1)c1ccc2c(c1)OCO2
  • InChi: 1S/C21H20N2O5/c1-13-5-14(2)7-16(6-13)22-21(24)11-25-10-17-9-19(28-23-17)15-3-4-18-20(8-15)27-12-26-18/h3-9H,10-12H2,1-2H3,(H,22,24)
  • InChiKey: JYFXYHHFSADRHT-UHFFFAOYSA-N  


Substructure search Similarity search

Network

Hover on a compound node to display the structore

Synonyms

  • 2-[[5-(1,3-benzodioxol-5-yl)isoxazol-3-yl]methoxy]-N-(3,5-dimethylphenyl)acetamide
  • 2-[[5-(1,3-benzodioxol-5-yl)-3-isoxazolyl]methoxy]-N-(3,5-dimethylphenyl)acetamide
  • 2-[[5-(1,3-benzodioxol-5-yl)-1,2-oxazol-3-yl]methoxy]-N-(3,5-dimethylphenyl)ethanamide
  • E613-0123
  • NCGC00123610-01

Targets

Known targets for this compound

Species Target name Source Bibliographic reference
Homo sapiens nuclear factor, erythroid 2-like 2 Starlite/ChEMBL No references

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Loa Loa (eye worm) GTP-binding nuclear protein RAN/TC4 0.0043 0.0054 0.0054
Trypanosoma cruzi Lanosterol 14-alpha demethylase 0.0063 0.0107 0.0084
Echinococcus granulosus lysine specific demethylase 5A 0.0166 0.0378 0.0525
Trypanosoma cruzi Lanosterol 14-alpha demethylase 0.0063 0.0107 0.0084
Loa Loa (eye worm) hypothetical protein 0.0047 0.0065 0.0065
Schistosoma mansoni cpg binding protein 0.0059 0.0095 0.0111
Brugia malayi Twik (KCNK-like) family of potassium channels, alpha subunit 28 0.0075 0.0137 0.0131
Trichomonas vaginalis maltase-glucoamylase, putative 0.0035 0.0033 0.0026
Mycobacterium tuberculosis Probable cytochrome P450 140 Cyp140 0.0063 0.0107 0.0209
Loa Loa (eye worm) hypothetical protein 0.047 0.1176 0.1176
Loa Loa (eye worm) hypothetical protein 0.2151 0.5598 0.5598
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0109 0.0227 0.0205
Loa Loa (eye worm) hypothetical protein 0.0031 0.0021 0.0021
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.0056 0.0088 0.0088
Onchocerca volvulus 0.0074 0.0134 0.051
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.0031 0.0022 0.001
Echinococcus multilocularis PHD finger protein rhinoceros 0.0029 0.0016 0.0022
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0031 0.0022 0.0016
Echinococcus granulosus voltage gated potassium channel 0.0028 0.0015 0.0021
Echinococcus multilocularis neuropeptide receptor 0.047 0.1176 0.1634
Echinococcus granulosus GPCR family 2 0.0049 0.0069 0.0095
Onchocerca volvulus 0.0103 0.0211 0.0814
Brugia malayi nuclear receptor NHR-88 0.0031 0.0022 0.0016
Leishmania major C-8 sterol isomerase-like protein 0.3826 1 1
Loa Loa (eye worm) hypothetical protein 0.0103 0.0211 0.0211
Toxoplasma gondii histone lysine acetyltransferase GCN5-A 0.0127 0.0275 0.3692
Plasmodium falciparum GTP-binding nuclear protein RAN/TC4 0.0043 0.0054 0.0541
Schistosoma mansoni sodium-dependent neurotransmitter transporter 0.0031 0.0021 0.0009
Loa Loa (eye worm) flap endonuclease-1 0.0057 0.009 0.009
Toxoplasma gondii glucose-6-phosphate 1-dehydrogenase 0.0064 0.0108 0.1435
Onchocerca volvulus 0.0047 0.0063 0.0229
Loa Loa (eye worm) hypothetical protein 0.0075 0.0137 0.0137
Schistosoma mansoni sex comb on midleg homolog 0.0054 0.0083 0.0094
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0031 0.0022 0.0016
Leishmania major cytochrome p450-like protein 0.0063 0.0107 0.0104
Loa Loa (eye worm) hypothetical protein 0.0074 0.0134 0.0134
Mycobacterium tuberculosis Probable cytochrome P450 123 Cyp123 0.0063 0.0107 0.0209
Schistosoma mansoni thyrotropin-releasing hormone receptor 0.047 0.1176 0.1617
Loa Loa (eye worm) ACC-1 protein 0.0103 0.0211 0.0211
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0307 0.0747 0.2499
Echinococcus granulosus ATP dependent Clp protease proteolytic subunit 0.0082 0.0156 0.0217
Toxoplasma gondii histone lysine acetyltransferase GCN5-B 0.0127 0.0275 0.3692
Loa Loa (eye worm) hypothetical protein 0.0075 0.0137 0.0137
Onchocerca volvulus Bile acid receptor homolog 0.0031 0.0022 0.0065
Loa Loa (eye worm) hypothetical protein 0.0069 0.0121 0.0121
Echinococcus multilocularis neuropeptides capa receptor 0.047 0.1176 0.1634
Schistosoma mansoni phosphatidylserine receptor 0.0043 0.0055 0.0055
Plasmodium vivax JmjC domain containing protein 0.0043 0.0055 0.0551
Trypanosoma cruzi calcium/potassium channel (CAKC), putative 0.0075 0.0137 0.0114
Loa Loa (eye worm) hypothetical protein 0.0143 0.0316 0.0316
Loa Loa (eye worm) cytochrome P450 family protein 0.0117 0.0249 0.0249
Echinococcus multilocularis FTZ F1 alpha 0.0031 0.0022 0.0031
Mycobacterium tuberculosis Probable isocitrate dehydrogenase [NADP] Icd1 (oxalosuccinate decarboxylase) (IDH) (NADP+-specific ICDH) (IDP) 0.0033 0.0028 0.0045
Loa Loa (eye worm) solute carrier family 6 member 4 0.0182 0.0418 0.0418
Loa Loa (eye worm) pyruvate kinase-PB 0.0024 0.0005 0.0005
Echinococcus multilocularis rhodopsin orphan GPCR 0.047 0.1176 0.1634
Trypanosoma brucei flap endonuclease-1 (FEN-1), putative 0.0057 0.009 0.0065
Loa Loa (eye worm) hypothetical protein 0.0182 0.0418 0.0418
Schistosoma mansoni alpha-galactosidase/alpha-n-acetylgalactosaminidase 0.0099 0.0202 0.026
Brugia malayi Twik (KCNK-like) family of potassium channels, alpha subunit 32 0.0075 0.0137 0.0131
Echinococcus granulosus short transient receptor potential channel 6 0.0071 0.0127 0.0177
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0047 0.0065 0.0059
Wolbachia endosymbiont of Brugia malayi fructose-1,6-bisphosphatase 0.0109 0.0227 0.9281
Schistosoma mansoni ran 0.0043 0.0054 0.0054
Trichomonas vaginalis 6-phosphogluconolactonase, putative 0.0107 0.0221 0.0677
Loa Loa (eye worm) hypothetical protein 0.0082 0.0155 0.0155
Loa Loa (eye worm) hypothetical protein 0.0082 0.0156 0.0156
Brugia malayi hypothetical protein 0.0031 0.0021 0.0016
Echinococcus granulosus histone acetyltransferase MYST2 0.0062 0.0102 0.0142
Leishmania major hypothetical protein, conserved 0.0103 0.021 0.0207
Treponema pallidum recombinase A 0.0113 0.0238 0.3052
Brugia malayi Inositol-1 0.0109 0.0227 0.0222
Schistosoma mansoni nAChR subunit 0.0047 0.0065 0.007
Echinococcus multilocularis potassium channel subfamily K 8 0.0075 0.0137 0.0191
Mycobacterium ulcerans cytochrome p450 150 cyp150 0.0063 0.0107 0.0347
Onchocerca volvulus 0.047 0.1176 0.4644
Leishmania major isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0033 0.0028 0.0025
Trichomonas vaginalis alpha-glucosidase, putative 0.0035 0.0033 0.0026
Trichomonas vaginalis conserved hypothetical protein 0.0052 0.0076 0.0177
Onchocerca volvulus 0.0075 0.0137 0.0522
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.0056 0.0088 0.0123
Echinococcus granulosus beta LACTamase domain containing family member 0.0074 0.0134 0.0187
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0052 0.0076 0.007
Loa Loa (eye worm) hypothetical protein 0.0103 0.0211 0.0211
Brugia malayi G-protein-linked acetylcholine receptor protein 2, putative 0.047 0.1176 0.1171
Schistosoma mansoni scm-relatedprotein containing 4 mbt domains (sfmbt) 0.0054 0.0083 0.0094
Trichomonas vaginalis glucosylceramidase, putative 0.0175 0.0401 0.1301
Echinococcus granulosus nicotinic acetylcholine receptor subunit type 0.0103 0.0211 0.0293
Echinococcus multilocularis short transient receptor potential channel 6 0.0071 0.0127 0.0177
Echinococcus granulosus neuronal acetylcholine receptor subunit alpha 4 0.0103 0.0211 0.0293
Loa Loa (eye worm) hypothetical protein 0.0043 0.0055 0.0055
Echinococcus granulosus neutral alpha glucosidase AB 0.0035 0.0033 0.0045
Onchocerca volvulus 0.0054 0.0083 0.0305
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0031 0.0022 0.0031
Trichomonas vaginalis D-aminoacylase, putative 0.0074 0.0134 0.0379
Brugia malayi G protein-coupled receptor 0.047 0.1176 0.1171
Brugia malayi AKH receptor 0.047 0.1176 0.1171
Echinococcus granulosus lysosomal alpha glucosidase 0.0158 0.0356 0.0495
Leishmania major 4-coumarate:coa ligase-like protein 0.0025 0.0006 0.0003
Mycobacterium ulcerans lipase LipD 0.0074 0.0134 0.0442
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0103 0.0211 0.0205
Loa Loa (eye worm) hypothetical protein 0.0103 0.0211 0.0211
Schistosoma mansoni alpha-1 adrenergic receptor 0.047 0.1176 0.1617
Schistosoma mansoni nAChR subunit 0.0103 0.0211 0.0273
Echinococcus granulosus 3 hydroxyacyl coenzyme A dehydrogenase type 2 0.006 0.0099 0.0137
Echinococcus granulosus histone acetyltransferase KAT2B 0.0127 0.0275 0.0382
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0035 0.0033 0.0026
Loa Loa (eye worm) hypothetical protein 0.047 0.1176 0.1176
Trypanosoma brucei importin beta-1 subunit, putative 0.0059 0.0095 0.007
Leishmania major mitogen activated protein kinase 4, putative;with=GeneDB:LmxM19.1440 0.0053 0.0079 0.0076
Plasmodium falciparum isocitrate dehydrogenase [NADP], mitochondrial 0.0033 0.0028 0.018
Mycobacterium ulcerans cytochrome P450 125A7 Cyp125A7 0.0063 0.0107 0.0347
Loa Loa (eye worm) carboxylesterase 0.0069 0.0121 0.0121
Onchocerca volvulus 0.0343 0.0841 0.3316
Trichomonas vaginalis glucosylceramidase, putative 0.0175 0.0401 0.1301
Leishmania major hypothetical protein, conserved 0.0075 0.0137 0.0134
Brugia malayi hypothetical protein 0.0047 0.0065 0.0059
Trypanosoma brucei C-8 sterol isomerase, putative 0.3826 1 1
Toxoplasma gondii histone lysine demethylase JMJD6a 0.0043 0.0055 0.0707
Leishmania major 3-oxoacyl-(acyl-carrier protein) reductase, putative 0.006 0.0099 0.0096
Echinococcus multilocularis tyrosyl DNA phosphodiesterase 1 0.013 0.0283 0.0393
Loa Loa (eye worm) hypothetical protein 0.0054 0.0083 0.0083
Toxoplasma gondii ion channel protein 0.0075 0.0137 0.1825
Brugia malayi RNA, U transporter 1 0.0167 0.0379 0.0374
Schistosoma mansoni alpha-galactosidase/alpha-n-acetylgalactosaminidase 0.0099 0.0202 0.026
Echinococcus multilocularis sodium and chloride dependent glycine 0.0031 0.0021 0.003
Echinococcus multilocularis nicotinic acetylcholine receptor subunit alpha 8 0.024 0.0572 0.0795
Loa Loa (eye worm) ACC-1 protein 0.0103 0.0211 0.0211
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0031 0.0021 0.0016
Brugia malayi Smad1 0.005 0.0073 0.0067
Brugia malayi Twik (KCNK-like) family of potassium channels, alpha subunit 7 0.0075 0.0137 0.0131
Mycobacterium leprae putative cytochrome p450 0.0063 0.0107 0.06
Echinococcus multilocularis G-protein coupled receptor, putative 0.047 0.1176 0.1634
Brugia malayi Voltage-gated potassium channel, EAG (KCNH1)-related. C. elegans egl-2 ortholog 0.0028 0.0015 0.0009
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0033 0.0028 0.0039
Plasmodium vivax glucose-6-phosphate 1-dehydrogenase, putative 0.0107 0.0221 0.2838
Leishmania major hypothetical protein, conserved 0.0033 0.0028 0.0025
Echinococcus multilocularis Cys loop ligand gated ion channel subunit 0.0103 0.0211 0.0293
Echinococcus multilocularis small conductance calcium activated potassium 0.1647 0.4271 0.5938
Echinococcus granulosus twik family of potassium channels 0.0075 0.0137 0.0191
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0031 0.0022 0.0016
Loa Loa (eye worm) MH1 domain-containing protein 0.005 0.0073 0.0073
Brugia malayi mbt repeat family protein 0.0054 0.0083 0.0077
Loa Loa (eye worm) hypothetical protein 0.0059 0.0095 0.0095
Leishmania major cytochrome p450-like protein 0.0117 0.0249 0.0246
Mycobacterium ulcerans cytochrome P450 143A4 Cyp143A4 0.0063 0.0107 0.0347
Echinococcus multilocularis musashi 0.0143 0.0316 0.044
Mycobacterium leprae possible inositol monophosphatase SubH (IMPase) (inositol-1-phosphatase) (I-1-Pase ). 0.0098 0.0197 0.1139
Schistosoma mansoni rhodopsin-like orphan GPCR 0.047 0.1176 0.1617
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.0031 0.0022 0.001
Brugia malayi Hypothetical glycine receptor like protein T20B12.9 in chromosome III 0.0103 0.0211 0.0205
Entamoeba histolytica hypothetical protein 0.0055 0.0086 0.0303
Trichomonas vaginalis sucrase-isomaltase, putative 0.0035 0.0033 0.0026
Echinococcus multilocularis rhodopsin orphan GPCR 0.047 0.1176 0.1634
Loa Loa (eye worm) hypothetical protein 0.047 0.1176 0.1176
Brugia malayi nuclear hormone receptor 0.0031 0.0022 0.0016
Loa Loa (eye worm) hypothetical protein 0.0054 0.0083 0.0083
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0125 0.0269 0.0354
Loa Loa (eye worm) GABA receptor subunit 0.0055 0.0086 0.0086
Loa Loa (eye worm) gonadotropin-releasing hormone receptor 2 0.047 0.1176 0.1176
Trypanosoma cruzi hypothetical protein, conserved 0.0035 0.0033 0.0009
Onchocerca volvulus 0.0983 0.2525 1
Echinococcus granulosus multidrug and toxin extrusion protein 2 0.0033 0.0028 0.0039
Brugia malayi neuropeptide F receptor 0.047 0.1176 0.1171
Loa Loa (eye worm) hypothetical protein 0.0055 0.0086 0.0086
Plasmodium falciparum amino acid transporter, putative 0.0031 0.0021 0.0093
Brugia malayi Twik (KCNK-like) family of potassium channels, alpha subunit 13 0.0075 0.0137 0.0131
Brugia malayi G-protein coupled receptor 0.047 0.1176 0.1171
Loa Loa (eye worm) hypothetical protein 0.047 0.1176 0.1176
Plasmodium vivax potassium channel, putative 0.0075 0.0137 0.1688
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.047 0.1176 0.1634
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.0074 0.0134 0.0266
Loa Loa (eye worm) neuropeptide F receptor 0.047 0.1176 0.1176
Echinococcus multilocularis nicotinic acetylcholine receptor a11 subunit 0.024 0.0572 0.0795
Mycobacterium ulcerans esterase/lipase LipP 0.0074 0.0134 0.0442
Schistosoma mansoni neuropeptide f receptor 76f 0.047 0.1176 0.1617
Echinococcus granulosus short transient receptor potential channel 6 0.0071 0.0127 0.0177
Mycobacterium leprae Probable pyruvate kinase PykA 0.0035 0.0032 0.0158
Schistosoma mansoni sodium/chloride dependent neurotransmitter transporter 0.0031 0.0021 0.0009
Echinococcus multilocularis Ataxin 2, N terminal,domain containing protein 0.0046 0.0061 0.0085
Mycobacterium ulcerans cytochrome P450 143A3 Cyp143A3 0.0063 0.0107 0.0347
Trichomonas vaginalis set domain proteins, putative 0.0983 0.2525 0.8654
Loa Loa (eye worm) hypothetical protein 0.047 0.1176 0.1176
Loa Loa (eye worm) latrophilin receptor protein 2 0.0049 0.0069 0.0069
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0125 0.0269 0.0354
Echinococcus granulosus neuropeptide Y receptor 0.047 0.1176 0.1634
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.047 0.1176 0.1617
Trichomonas vaginalis pyruvate kinase, putative 0.0035 0.0032 0.0026
Mycobacterium ulcerans cytochrome P450 136A2 Cyp136A2 0.0063 0.0107 0.0347
Entamoeba histolytica Rad52/22 family double-strand break repair protein, putative 0.0298 0.0724 0.2675
Leishmania major hypothetical protein, conserved 0.0074 0.0134 0.0132
Loa Loa (eye worm) nuclear factor I 0.0028 0.0013 0.0013
Brugia malayi Cell death protein 3 precursor 0.0102 0.0208 0.0202
Mycobacterium tuberculosis Probable cytochrome P450 138 Cyp138 0.0063 0.0107 0.0209
Loa Loa (eye worm) hypothetical protein 0.1955 0.5082 0.5082
Brugia malayi sulfakinin receptor protein 0.047 0.1176 0.1171
Onchocerca volvulus 0.0031 0.0021 0.0062
Loa Loa (eye worm) hypothetical protein 0.0028 0.0015 0.0015
Trypanosoma brucei GTP-binding nuclear protein rtb2, putative 0.0043 0.0054 0.0029
Echinococcus granulosus neuropeptide Y receptor 0.047 0.1176 0.1634
Schistosoma mansoni hypothetical protein 0.047 0.1176 0.1617
Mycobacterium tuberculosis NADPH-dependent mycothiol reductase Mtr 0.004 0.0045 0.0081
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0307 0.0747 0.2499
Echinococcus granulosus ecdysone induced protein 78C 0.0031 0.0022 0.0031
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0864 0.2212 0.2212
Brugia malayi neuropeptide F receptor 0.047 0.1176 0.1171
Toxoplasma gondii exonuclease III APE 0.0056 0.0088 0.1163
Brugia malayi cytoplasmic intermediate filament protein 0.0077 0.0142 0.0136
Echinococcus granulosus sex peptide receptor 0.047 0.1176 0.1634
Brugia malayi hypothetical protein 0.0047 0.0065 0.0059
Schistosoma mansoni ubiquitin-specific peptidase 2 (C19 family) 0.0052 0.0076 0.0085
Brugia malayi hypothetical protein 0.047 0.1176 0.1171
Echinococcus granulosus neuropeptide receptor 0.047 0.1176 0.1634
Trichomonas vaginalis CMGC family protein kinase 0.0053 0.0079 0.0188
Brugia malayi Twik (KCNK-like) family of potassium channels, alpha subunit 45 0.0075 0.0137 0.0131
Loa Loa (eye worm) uncoordinated protein 58 0.0075 0.0137 0.0137
Loa Loa (eye worm) hypothetical protein 0.0035 0.0033 0.0033
Echinococcus granulosus biogenic amine 5HT receptor 0.2151 0.5598 0.7781
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0052 0.0076 0.0177
Brugia malayi larval opioid receptor 0.047 0.1176 0.1171
Mycobacterium tuberculosis Probable ATP-dependent CLP protease proteolytic subunit 1 ClpP1 (endopeptidase CLP) 0.0054 0.0082 0.0157
Plasmodium vivax isocitrate dehydrogenase [NADP], mitochondrial, putative 0.0033 0.0028 0.018
Onchocerca volvulus Neuropeptide F receptor homolog 0.047 0.1176 0.4644
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0307 0.0747 0.2499
Schistosoma mansoni myosin xvIII 0.047 0.1176 0.1617
Trypanosoma cruzi calcium-activated potassium channel, putative 0.0075 0.0137 0.0114
Loa Loa (eye worm) hypothetical protein 0.0085 0.0165 0.0165
Echinococcus granulosus TWiK family of potassium channels protein 7 0.0075 0.0137 0.0191
Echinococcus multilocularis Cys loop ligand gated ion channel subunit 0.0047 0.0065 0.0091
Trichomonas vaginalis ran, putative 0.0043 0.0054 0.01
Echinococcus multilocularis peptidase Clp (S14 family) 0.0054 0.0082 0.0114
Loa Loa (eye worm) hypothetical protein 0.0044 0.0055 0.0055
Schistosoma mansoni nAChR subunit 0.0103 0.0211 0.0273
Leishmania major calcium/potassium channel (CAKC), putative 0.0075 0.0137 0.0134
Echinococcus multilocularis short transient receptor potential channel 6 0.0071 0.0127 0.0177
Loa Loa (eye worm) hypothetical protein 0.0047 0.0065 0.0065
Plasmodium vivax hypothetical protein, conserved 0.0031 0.0021 0.0093
Echinococcus granulosus fmrfamide receptor 0.047 0.1176 0.1634
Trypanosoma brucei PAB1-binding protein , putative 0.0103 0.021 0.0186
Echinococcus granulosus neuropeptide receptor A26 0.047 0.1176 0.1634
Entamoeba histolytica hypothetical protein 0.0043 0.0055 0.0186
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.006 0.0099 0.0319
Onchocerca volvulus 0.047 0.1176 0.4644
Echinococcus multilocularis transient receptor potential gamma protein 0.0103 0.0212 0.0294
Echinococcus granulosus lipoxygenase domain containing protein 0.0059 0.0095 0.0133
Loa Loa (eye worm) hypothetical protein 0.047 0.1176 0.1176
Echinococcus multilocularis potassium voltage gated channel subfamily H 0.0028 0.0015 0.0021
Echinococcus granulosus cytoplasmic intermediate filament protein 0.0069 0.0122 0.0169
Schistosoma mansoni smad1 5 8 and 0.005 0.0073 0.008
Mycobacterium ulcerans cytochrome P450 144A4 Cyp144A4 0.0063 0.0107 0.0347
Loa Loa (eye worm) hypothetical protein 0.0025 0.0006 0.0006
Toxoplasma gondii glucose-6-phosphate 1-dehydrogenase 0.0107 0.0221 0.2956
Loa Loa (eye worm) pyruvate kinase 0.0035 0.0032 0.0032
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0049 0.0069 0.0095
Mycobacterium ulcerans cytochrome P450 191A3 Cyp191A3 0.0063 0.0107 0.0347
Mycobacterium leprae PROBABLE ATP-DEPENDENT CLP PROTEASE PROTEOLYTIC SUBUNIT 1 CLPP1 (ENDOPEPTIDASE CLP) 0.0054 0.0082 0.0452
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0033 0.0028 0.0039
Leishmania major 4-coumarate:coa ligase-like protein 0.0025 0.0006 0.0003
Onchocerca volvulus 0.0103 0.0211 0.0814
Loa Loa (eye worm) beta-lactamase 0.0074 0.0134 0.0134
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative 0.0056 0.0088 0.0064
Loa Loa (eye worm) hypothetical protein 0.2151 0.5598 0.5598
Echinococcus multilocularis nicotinic acetylcholine receptor subunit type 0.0047 0.0065 0.0091
Mycobacterium ulcerans cytochrome P450 188A3 Cyp188A3 0.0063 0.0107 0.0347
Loa Loa (eye worm) hypothetical protein 0.0047 0.0065 0.0065
Echinococcus granulosus calcium activated potassium channel variant 0.0075 0.0137 0.0191
Toxoplasma gondii CMGC kinase, MAPK family (ERK) MAPK-1 0.0053 0.0079 0.104
Schistosoma mansoni nAChR subunit 0.0103 0.0211 0.0273
Onchocerca volvulus 0.0047 0.0065 0.0236
Loa Loa (eye worm) hypothetical protein 0.047 0.1176 0.1176
Brugia malayi hypothetical protein 0.0171 0.0391 0.0385
Onchocerca volvulus Cell death protein 3 homolog 0.0102 0.0208 0.0803
Loa Loa (eye worm) cytoplasmic intermediate filament protein 0.0077 0.0142 0.0142
Loa Loa (eye worm) hypothetical protein 0.0075 0.0137 0.0137
Echinococcus granulosus retinoic acid receptor rxr beta a 0.0031 0.0022 0.0031
Schistosoma mansoni high voltage-activated calcium channel Cav1 0.0085 0.0165 0.0209
Leishmania major lanosterol 14-alpha-demethylase, putative 0.0063 0.0107 0.0104
Echinococcus multilocularis uncharacterized sodium dependent transporter 0.0031 0.0021 0.003
Brugia malayi hypothetical protein 0.047 0.1176 0.1171
Mycobacterium ulcerans adenosylmethionine-8-amino-7-oxononanoate aminotransferase 0.0147 0.0328 0.1108
Brugia malayi isocitrate dehydrogenase 0.0033 0.0028 0.0022
Toxoplasma gondii pyruvate kinase PyK1 0.0035 0.0032 0.0405
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.0307 0.0747 0.2759
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.0043 0.0054 0.0031
Loa Loa (eye worm) hypothetical protein 0.0075 0.0137 0.0137
Brugia malayi Carboxylesterase family protein 0.0069 0.0121 0.0115
Loa Loa (eye worm) norepinephrine transporter 0.0182 0.0418 0.0418
Loa Loa (eye worm) S-phase kinase-associated protein 1A 0.0075 0.0137 0.0137
Echinococcus multilocularis muscleblind protein 1 0.0168 0.0381 0.053
Toxoplasma gondii inositol(myo)-1(or 4)-monophosphatase 2, putative 0.0109 0.0227 0.3048
Echinococcus granulosus tm gpcr rhodopsin 0.047 0.1176 0.1634
Loa Loa (eye worm) Sodium:neurotransmitter symporter family protein 0.0031 0.0021 0.0021
Toxoplasma gondii HEAT repeat-containing protein 0.0059 0.0095 0.125
Loa Loa (eye worm) hypothetical protein 0.0074 0.0134 0.0134
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.0031 0.0022 0.0022
Brugia malayi Latrophilin receptor protein 2 0.0049 0.0069 0.0063
Schistosoma mansoni sodium-dependent neurotransmitter transporter 0.0031 0.0021 0.0009
Mycobacterium ulcerans ion transport protein 0.0075 0.0137 0.0452
Entamoeba histolytica Flap nuclease, putative 0.0057 0.009 0.0317
Schistosoma mansoni biogenic amine (dopamine) receptor 0.047 0.1176 0.1617
Mycobacterium leprae Conserved hypothetical protein 0.0664 0.1687 1
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0031 0.0022 0.0031
Brugia malayi Nuclear hormone receptor family member nhr-40 0.0031 0.0022 0.0016
Brugia malayi hypothetical protein 0.047 0.1176 0.1171
Trichomonas vaginalis glutaminase, putative 0.1131 0.2914 1
Echinococcus granulosus histone lysine methyltransferase setb 0.0125 0.0269 0.0374
Echinococcus multilocularis ecdysone induced protein 78C 0.0031 0.0022 0.0031
Schistosoma mansoni hypothetical protein 0.0082 0.0155 0.0195
Echinococcus multilocularis potassium channel subfamily K 0.0075 0.0137 0.0191
Echinococcus multilocularis lysine specific demethylase 5A 0.0163 0.0369 0.0513
Trypanosoma brucei glucose-6-phosphate 1-dehydrogenase 0.0098 0.0198 0.0173
Loa Loa (eye worm) pyruvate kinase 0.0035 0.0032 0.0032
Loa Loa (eye worm) hypothetical protein 0.0031 0.0022 0.0022
Echinococcus granulosus snurportin 1 0.0627 0.1589 0.2209
Loa Loa (eye worm) hypothetical protein 0.024 0.0572 0.0572
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.0031 0.0022 0.001
Schistosoma mansoni biogenic amine receptor 0.047 0.1176 0.1617
Echinococcus multilocularis polycomb protein SCMH1 0.0054 0.0083 0.0115
Loa Loa (eye worm) hypothetical protein 0.0103 0.0211 0.0211
Echinococcus multilocularis voltage dependent calcium channel 0.0085 0.0165 0.0229
Plasmodium vivax importin-beta 2, putative 0.0059 0.0095 0.1103
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.0031 0.0022 0.0031
Trichomonas vaginalis alpha-glucosidase, putative 0.0035 0.0033 0.0026
Loa Loa (eye worm) hypothetical protein 0.0055 0.0086 0.0086
Loa Loa (eye worm) hypothetical protein 0.0075 0.0137 0.0137
Echinococcus granulosus microtubule associated protein 2 0.2758 0.7194 1
Trypanosoma cruzi hypothetical protein, conserved 0.0033 0.0028 0.0005
Brugia malayi acetylcholine receptor protein, alpha-like chain, putative 0.0103 0.0211 0.0205
Echinococcus granulosus lamin dm0 0.0143 0.0316 0.044
Loa Loa (eye worm) hypothetical protein 0.3826 1 1
Toxoplasma gondii hypothetical protein 0.0028 0.0015 0.0165
Echinococcus granulosus nicotinic acetylcholine receptor a11 subunit 0.024 0.0572 0.0795
Entamoeba histolytica Ran family GTPase 0.0043 0.0054 0.0184
Onchocerca volvulus 0.0047 0.0065 0.0236
Schistosoma mansoni nAChR subunit 0.0047 0.0065 0.007
Loa Loa (eye worm) O-glycosyl hydrolase family 30 protein 0.0267 0.0642 0.0642
Echinococcus multilocularis neutral alpha glucosidase AB 0.0035 0.0033 0.0045
Plasmodium falciparum JmjC domain-containing protein, putative 0.0043 0.0055 0.0551
Mycobacterium tuberculosis Probable aminotransferase 0.0147 0.0328 0.0667
Mycobacterium ulcerans recombinase A 0.0113 0.0238 0.0799
Schistosoma mansoni jumonji domain containing protein 0.0043 0.0055 0.0055
Entamoeba histolytica acyl-coA synthetase, putative 0.0025 0.0006 0.0005
Loa Loa (eye worm) acetylcholinesterase 1 0.0069 0.0121 0.0121
Loa Loa (eye worm) nucleolar RNA-associated protein alpha 0.0627 0.1589 0.1589
Loa Loa (eye worm) hypothetical protein 0.0031 0.0022 0.0022
Schistosoma mansoni opsin-like receptor 0.047 0.1176 0.1617
Brugia malayi Unidentified vitellogenin-linked transcript protein 6, putative 0.047 0.1176 0.1171
Mycobacterium tuberculosis RecA protein (recombinase A) [contains: endonuclease PI-MTUI (MTU RecA intein)]. 0.1864 0.4842 1
Echinococcus multilocularis p2X purinoceptor 4 0.0067 0.0116 0.0161
Echinococcus multilocularis neuropeptide receptor A26 0.047 0.1176 0.1634
Loa Loa (eye worm) hypothetical protein 0.0047 0.0065 0.0065
Schistosoma mansoni transient receptor potential channel 0.0103 0.0212 0.0274
Treponema pallidum glucose-6-phosphate 1-dehydrogenase 0.0098 0.0198 0.2499
Plasmodium falciparum ATP-dependent Clp protease proteolytic subunit 0.0082 0.0156 0.195
Brugia malayi Hypothetical glycine receptor like protein T20B12.9 in chromosome III 0.0055 0.0086 0.008
Loa Loa (eye worm) potassium voltage-gated channel subfamily Q member 5 0.0075 0.0137 0.0137
Brugia malayi hypothetical protein 0.047 0.1176 0.1171
Schistosoma mansoni neurotransmitter gated ion channel 0.0047 0.0065 0.007
Loa Loa (eye worm) hypothetical protein 0.1647 0.4271 0.4271
Brugia malayi Neurotransmitter-gated ion-channel transmembrane region family protein 0.0055 0.0086 0.008
Brugia malayi jmjC domain containing protein 0.0043 0.0055 0.0049
Brugia malayi hypothetical protein 0.0047 0.0065 0.0059
Mycobacterium tuberculosis Possible transmembrane cation transporter 0.0075 0.0137 0.0272
Entamoeba histolytica Acid sphingomyelinase-like phosphodiesterase, putative 0.0169 0.0384 0.1412
Echinococcus multilocularis TWiK family of potassium channels protein 7 0.0075 0.0137 0.0191
Mycobacterium leprae DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE 0.0101 0.0205 0.1185
Brugia malayi Bromodomain containing protein 0.0039 0.0044 0.0038
Brugia malayi MH1 domain containing protein 0.0028 0.0013 0.0008
Trypanosoma cruzi pyruvate kinase 2, putative 0.0035 0.0032 0.0009
Loa Loa (eye worm) hypothetical protein 0.047 0.1176 0.1176
Brugia malayi Twik (KCNK-like) family of potassium channels, alpha subunit 39B 0.0075 0.0137 0.0131
Echinococcus granulosus sodium and chloride dependent glycine 0.0031 0.0021 0.003
Onchocerca volvulus 0.0038 0.004 0.0135
Loa Loa (eye worm) hypothetical protein 0.0074 0.0134 0.0134
Echinococcus multilocularis serotonin receptor 0.2151 0.5598 0.7781
Loa Loa (eye worm) hypothetical protein 0.0031 0.0022 0.0022
Loa Loa (eye worm) hypothetical protein 0.047 0.1176 0.1176
Loa Loa (eye worm) hypothetical protein 0.0055 0.0086 0.0086
Echinococcus granulosus Smad4 0.005 0.0073 0.0101
Echinococcus granulosus neuropeptides capa receptor 0.047 0.1176 0.1634
Onchocerca volvulus 0.0031 0.0022 0.0065
Brugia malayi Voltage-gated potassium channel, HERG (KCNH2)-related. C. elegans unc-103 ortholog 0.0082 0.0157 0.0151
Loa Loa (eye worm) neuronal acetylcholine receptor protein 0.0047 0.0065 0.0065
Loa Loa (eye worm) jmjC domain-containing protein 0.0166 0.0378 0.0378
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.0031 0.0022 0.0031
Brugia malayi exodeoxyribonuclease III family protein 0.0056 0.0088 0.0083
Brugia malayi GnHR receptor homolog 0.047 0.1176 0.1171
Brugia malayi jmjC domain containing protein 0.0043 0.0055 0.0049
Onchocerca volvulus 0.0047 0.0065 0.0236
Echinococcus granulosus cpg binding protein 0.0062 0.0103 0.0144
Toxoplasma gondii glycosyl hydrolase, family 31 protein 0.0035 0.0033 0.0407
Brugia malayi Nuclear hormone receptor family member nhr-1 0.0031 0.0022 0.0016
Mycobacterium tuberculosis Possible cytochrome P450 135B1 Cyp135B1 0.0063 0.0107 0.0209
Brugia malayi acetylcholine receptor, alpha-type subunit unc-38 precursor 0.0103 0.0211 0.0205
Echinococcus multilocularis cytoplasmic intermediate filament protein 0.0069 0.0122 0.0169
Brugia malayi Pyruvate kinase, muscle isozyme 0.0035 0.0032 0.0027
Brugia malayi Twik (KCNK-like) family of potassium channels, alpha subunit 19. C. elegans unc-58 ortholog 0.0075 0.0137 0.0131
Loa Loa (eye worm) hypothetical protein 0.077 0.1964 0.1964
Leishmania major GTP-binding protein, putative 0.0043 0.0054 0.0051
Trypanosoma cruzi hypothetical protein, conserved 0.0033 0.0028 0.0005
Entamoeba histolytica hypothetical protein 0.0043 0.0055 0.0186
Loa Loa (eye worm) hypothetical protein 0.0103 0.0211 0.0211
Trypanosoma cruzi tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.013 0.0283 0.026
Trypanosoma cruzi mitogen activated protein kinase 4, putative 0.0053 0.0079 0.0056
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0048 0.0066 0.014
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0103 0.0211 0.0205
Trichomonas vaginalis glucosamine-6-phosphate isomerase, putative 0.0107 0.0221 0.0677
Loa Loa (eye worm) TYRA-2 protein 0.047 0.1176 0.1176
Loa Loa (eye worm) inositol-1 0.0109 0.0227 0.0227
Onchocerca volvulus 0.0075 0.0137 0.0522
Loa Loa (eye worm) hypothetical protein 0.0029 0.0016 0.0016
Brugia malayi Twik (KCNK-like) family of potassium channels, alpha subunit 38. C. elegans sup-9 ortholog 0.0075 0.0137 0.0131
Plasmodium falciparum phd finger protein, putative 0.0029 0.0016 0.0013
Brugia malayi Cytochrome P450 family protein 0.0063 0.0107 0.0101
Echinococcus multilocularis microtubule associated protein 2 0.2758 0.7194 1
Giardia lamblia Glucose-6-phosphate 1-dehydrogenase 0.0107 0.0221 0.0765
Schistosoma mansoni Smad4 0.005 0.0073 0.008
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0307 0.0747 0.2499
Loa Loa (eye worm) ligand-Gated ion Channel family member 0.0103 0.0211 0.0211
Echinococcus granulosus PHD finger protein rhinoceros 0.0029 0.0016 0.0022
Echinococcus granulosus voltage dependent calcium channel type d subunit|voltage dependent calcium channel|voltage dependent L type calcium channel subu 0.0085 0.0165 0.0229
Echinococcus multilocularis jumonji domain containing 1A 0.0043 0.0055 0.0076
Mycobacterium tuberculosis Possible cytochrome P450 126 Cyp126 0.0063 0.0107 0.0209
Trypanosoma brucei trypanothione reductase 0.004 0.0045 0.002
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0047 0.0065 0.0059
Trichomonas vaginalis ap endonuclease, putative 0.0056 0.0088 0.0219
Loa Loa (eye worm) hypothetical protein 0.0075 0.0137 0.0137
Echinococcus granulosus ubiquitin specific protease 41 0.0052 0.0076 0.0106
Brugia malayi hypothetical protein 0.012 0.0256 0.025
Onchocerca volvulus 0.047 0.1176 0.4644
Mycobacterium tuberculosis Cytochrome P450 121 Cyp121 0.0063 0.0107 0.0209
Leishmania major cytochrome p450-like protein 0.0063 0.0107 0.0104
Echinococcus granulosus flap endonuclease 1 0.0057 0.009 0.0125
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.0031 0.0022 0.0022
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0125 0.0269 0.0354
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0103 0.0211 0.0205
Mycobacterium ulcerans cytochrome P450 140A5 Cyp140A5 0.0063 0.0107 0.0347
Onchocerca volvulus 0.0031 0.0021 0.0062
Echinococcus multilocularis voltage dependent L type calcium channel subunit 0.0085 0.0165 0.0229
Echinococcus granulosus G protein coupled 5 hydroxytryptamine receptor 0.047 0.1176 0.1634
Loa Loa (eye worm) hypothetical protein 0.0075 0.0137 0.0137
Mycobacterium tuberculosis Possible penicillin-binding protein 0.0471 0.118 0.2428
Echinococcus multilocularis JmjC domain containing protein 4 0.0043 0.0055 0.0076
Echinococcus multilocularis endonuclease exonuclease phosphatase 0.0224 0.0531 0.0738
Brugia malayi Twik (KCNK-like) family of potassium channels, alpha subunit 17 0.0075 0.0137 0.0131
Plasmodium falciparum AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0056 0.0088 0.1015
Trypanosoma cruzi pyruvate kinase 2, putative 0.0035 0.0032 0.0009
Loa Loa (eye worm) transcription factor SMAD2 0.0738 0.1881 0.1881
Brugia malayi PHD-finger family protein 0.0029 0.0016 0.001
Loa Loa (eye worm) hypothetical protein 0.047 0.1176 0.1176
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0085 0.0164 0.048
Loa Loa (eye worm) hypothetical protein 0.0103 0.0211 0.0211
Mycobacterium tuberculosis Probable hydrolase 0.0074 0.0134 0.0266
Schistosoma mansoni growth hormone secretagogue receptor 0.047 0.1176 0.1617
Echinococcus granulosus histone acetyltransferase KAT2B 0.0421 0.1046 0.1454
Loa Loa (eye worm) hypothetical protein 0.0075 0.0137 0.0137
Plasmodium vivax SET domain protein, putative 0.0125 0.0269 0.3505
Loa Loa (eye worm) hypothetical protein 0.047 0.1176 0.1176
Trypanosoma brucei MATE efflux family protein, putative 0.0033 0.0028 0.0003
Loa Loa (eye worm) hypothetical protein 0.0055 0.0086 0.0086
Onchocerca volvulus 0.0438 0.1091 0.4308
Echinococcus multilocularis suppression of tumorigenicity 18 protein 0.0062 0.0102 0.0142
Leishmania major peptidyl-prolyl cis-trans isomerase/rotamase, putative,PPIase, putative 0.0032 0.0025 0.0022
Echinococcus multilocularis jumonji domain containing protein 0.004 0.0045 0.0063
Echinococcus multilocularis neuropeptide Y receptor 0.047 0.1176 0.1634
Echinococcus granulosus dnaJ subfamily B 0.0835 0.2137 0.2971
Echinococcus multilocularis snurportin 1 0.0627 0.1589 0.2209
Mycobacterium ulcerans cytochrome P450 187A4 Cyp187A4 0.0063 0.0107 0.0347
Loa Loa (eye worm) hypothetical protein 0.0075 0.0137 0.0137
Loa Loa (eye worm) hypothetical protein 0.047 0.1176 0.1176
Trypanosoma cruzi C-8 sterol isomerase, putative 0.3826 1 1
Schistosoma mansoni glutaminase 0.1131 0.2914 0.4038
Loa Loa (eye worm) hypothetical protein 0.0075 0.0137 0.0137
Echinococcus multilocularis lysine specific demethylase 6a 0.0043 0.0055 0.0076
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0049 0.0069 0.0095
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0141 0.0312 0.0434
Giardia lamblia Kinase, CMGC MAPK 0.0053 0.0079 0.0237
Brugia malayi hypothetical protein 0.0066 0.0114 0.0109
Loa Loa (eye worm) hypothetical protein 0.0154 0.0345 0.0345
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.0031 0.0022 0.0031
Echinococcus granulosus inositol monophosphatase 1 0.0109 0.0227 0.0316
Loa Loa (eye worm) hypothetical protein 0.0103 0.0211 0.0211
Loa Loa (eye worm) hypothetical protein 0.0168 0.0381 0.0381
Loa Loa (eye worm) hypothetical protein 0.047 0.1176 0.1176
Onchocerca volvulus 0.0241 0.0574 0.2254
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0307 0.0747 0.2499
Brugia malayi hypothetical protein 0.0075 0.0137 0.0131
Brugia malayi Flap endonuclease-1 0.0057 0.009 0.0084
Loa Loa (eye worm) hypothetical protein 0.014 0.031 0.031
Loa Loa (eye worm) hypothetical protein 0.0182 0.0418 0.0418
Echinococcus multilocularis RUN 0.0059 0.0095 0.0133
Schistosoma mansoni Cys-loop ligand gated ion channel subunit 0.0055 0.0086 0.0099
Toxoplasma gondii histone lysine demethylase JMJC1/KDM5D/JARID1D 0.0043 0.0055 0.0707
Schistosoma mansoni twik family of potassium channels-related 0.0075 0.0137 0.017
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0141 0.0312 0.0434
Loa Loa (eye worm) hypothetical protein 0.0168 0.0381 0.0381
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0141 0.0312 0.0312
Mycobacterium tuberculosis Probable cytochrome P450 144 Cyp144 0.0063 0.0107 0.0209
Echinococcus granulosus Cys loop ligand gated ion channel subunit 0.0103 0.0211 0.0293
Trypanosoma cruzi hypothetical protein, conserved 0.0035 0.0033 0.0009
Echinococcus multilocularis apoptotic protease activating factor 1 0.0082 0.0155 0.0216
Schistosoma mansoni biogenic amine (5HT) receptor 0.2151 0.5598 0.7777
Brugia malayi MH2 domain containing protein 0.005 0.0073 0.0067
Schistosoma mansoni hypothetical protein 0.0029 0.0016 0.0001
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0154 0.0345 0.034
Schistosoma mansoni smad1 5 8 and 0.005 0.0073 0.008
Brugia malayi ORL1-like opioid receptor 0.047 0.1176 0.1171
Trypanosoma cruzi calcium-activated potassium channel, putative 0.0075 0.0137 0.0114
Toxoplasma gondii peptidylprolyl isomerase 0.0032 0.0025 0.0304
Echinococcus multilocularis g protein coupled receptor 0.047 0.1176 0.1634
Schistosoma mansoni hypothetical protein 0.047 0.1176 0.1617
Loa Loa (eye worm) G-protein-linked acetylcholine receptor protein 2 0.047 0.1176 0.1176
Brugia malayi Nuclear hormone receptor family member nhr-41 0.0031 0.0022 0.0016
Echinococcus multilocularis dro:myosuppressin receptor 0.047 0.1176 0.1634
Schistosoma mansoni biogenic amine (dopamine) receptor 0.047 0.1176 0.1617
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0125 0.0269 0.3612
Schistosoma mansoni hypothetical protein 0.0835 0.2137 0.2956
Schistosoma mansoni transient receptor potential channel 4 0.0103 0.0212 0.0274
Echinococcus granulosus pyroglutamylated rfamide peptide receptor 0.047 0.1176 0.1634
Loa Loa (eye worm) hypothetical protein 0.047 0.1176 0.1176
Loa Loa (eye worm) hypothetical protein 0.0047 0.0065 0.0065
Echinococcus granulosus JmjC domain containing protein 4 0.0043 0.0055 0.0076
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 8 0.0052 0.0076 0.0106
Toxoplasma gondii ABC1 family protein 0.0074 0.0134 0.1786
Schistosoma mansoni neuropeptide receptor 0.047 0.1176 0.1617
Echinococcus multilocularis potassium voltage gated channel subfamily H 0.0082 0.0157 0.0218
Echinococcus granulosus nAChR subunit 0.0055 0.0086 0.012
Loa Loa (eye worm) hypothetical protein 0.0169 0.0384 0.0384
Schistosoma mansoni aryl hydrocarbon receptor 0.0051 0.0075 0.0083
Loa Loa (eye worm) voltage and ligand gated potassium channel 0.0082 0.0157 0.0157
Brugia malayi Pre-SET motif family protein 0.0864 0.2212 0.2207
Brugia malayi Dopamine receptor 0.047 0.1176 0.1171
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.0043 0.0054 0.0031
Trichomonas vaginalis glucosylceramidase, putative 0.0267 0.0642 0.2136
Echinococcus granulosus lamin 0.0143 0.0316 0.044
Loa Loa (eye worm) hypothetical protein 0.0075 0.0137 0.0137
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.0056 0.0088 0.0123
Echinococcus multilocularis Glycoside hydrolase, family 27 0.0099 0.0202 0.028
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0049 0.0069 0.0063
Mycobacterium ulcerans cytochrome P450 187A5 Cyp187A5 0.0063 0.0107 0.0347
Schistosoma mansoni amine GPCR 0.047 0.1176 0.1617
Mycobacterium ulcerans beta-lactamase 0.0074 0.0134 0.0442
Toxoplasma gondii thioredoxin reductase 0.004 0.0045 0.0572
Echinococcus multilocularis Multi antimicrobial extrusion protein MatE 0.003 0.002 0.0028
Loa Loa (eye worm) hypothetical protein 0.012 0.0256 0.0256
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0043 0.0055 0.0076
Echinococcus granulosus sodium dependent neurotransmitter transporter 0.0031 0.0021 0.003
Plasmodium vivax histone acetyltransferase GCN5, putative 0.0127 0.0275 0.3587
Giardia lamblia Fructose-bisphosphate aldolase 0.0307 0.0747 0.2729
Echinococcus multilocularis nicotinic acetylcholine receptor beta 1 subunit 0.0103 0.0211 0.0293
Loa Loa (eye worm) CMGC/MAPK/ERK1 protein kinase 0.0053 0.0079 0.0079
Schistosoma mansoni rhodopsin-like orphan GPCR 0.047 0.1176 0.1617
Schistosoma mansoni rab6-interacting 0.0059 0.0095 0.0112
Schistosoma mansoni alpha-glucosidase 0.0136 0.0298 0.0394
Brugia malayi Dopamine receptor protein 1, putative (partial) 0.047 0.1176 0.1171
Schistosoma mansoni histamine h1 receptor 0.047 0.1176 0.1617
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0031 0.0022 0.0016
Loa Loa (eye worm) hypothetical protein 0.047 0.1176 0.1176
Loa Loa (eye worm) hypothetical protein 0.047 0.1176 0.1176
Echinococcus multilocularis thyrotropin releasing hormone receptor 0.047 0.1176 0.1634
Schistosoma mansoni lipoxygenase 0.0287 0.0694 0.0946
Plasmodium falciparum potassium channel 0.0075 0.0137 0.1688
Brugia malayi putative neuropeptide receptor NPR1 0.047 0.1176 0.1171
Trypanosoma brucei tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.013 0.0283 0.0258
Echinococcus granulosus rhodopsin orphan GPCR 0.047 0.1176 0.1634
Onchocerca volvulus Putative nachr subunit 0.024 0.0572 0.2248
Loa Loa (eye worm) hypothetical protein 0.0075 0.0137 0.0137
Echinococcus multilocularis cpg binding protein 0.0062 0.0103 0.0144
Loa Loa (eye worm) hypothetical protein 0.0062 0.0102 0.0102
Brugia malayi Neuronal acetylcholine receptor protein, alpha-2 chain precursor 0.0047 0.0065 0.0059
Echinococcus granulosus Ataxin 2 N terminaldomain containing protein 0.0046 0.0061 0.0085
Wolbachia endosymbiont of Brugia malayi recombinase A 0.0113 0.0238 1
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.0031 0.0022 0.0022
Echinococcus granulosus neuropeptides capa receptor 0.047 0.1176 0.1634
Plasmodium vivax hypothetical protein, conserved 0.0074 0.0134 0.1649
Loa Loa (eye worm) hypothetical protein 0.0032 0.0025 0.0025
Echinococcus granulosus RUN 0.0059 0.0095 0.0133
Brugia malayi ecdysteroid receptor 0.0031 0.0022 0.0016
Echinococcus granulosus glycine receptor subunit alpha 1 0.0103 0.0211 0.0293
Brugia malayi Nuclear hormone receptor-like 1 0.0031 0.0022 0.0016
Trypanosoma cruzi hypothetical protein, conserved 0.0075 0.0137 0.0114
Trichomonas vaginalis D-aminoacylase, putative 0.0074 0.0134 0.0379
Mycobacterium ulcerans exodeoxyribonuclease III protein XthA 0.0056 0.0088 0.0284
Schistosoma mansoni alpha-glucosidase 0.0136 0.0298 0.0394
Loa Loa (eye worm) G-protein coupled receptor 0.047 0.1176 0.1176
Mycobacterium tuberculosis Possible cytochrome P450 135A1 Cyp135A1 0.0063 0.0107 0.0209
Echinococcus multilocularis Peptidase C19, ubiquitin carboxyl terminal hydrolase 2 0.0052 0.0076 0.0106
Echinococcus multilocularis phd:f box containing protein 0.0043 0.0055 0.0076
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0307 0.0747 0.2499
Echinococcus multilocularis Alpha N acetylgalactosaminidase 0.0099 0.0202 0.028
Loa Loa (eye worm) hypothetical protein 0.0075 0.0137 0.0137
Onchocerca volvulus 0.0143 0.0316 0.1233
Onchocerca volvulus Huntingtin homolog 0.012 0.0256 0.0992
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.0031 0.0022 0.0022
Loa Loa (eye worm) hypothetical protein 0.0193 0.0449 0.0449
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.0031 0.0022 0.0031
Schistosoma mansoni rhodopsin-like orphan GPCR 0.047 0.1176 0.1617
Echinococcus granulosus tm gpcr rhodopsin 0.047 0.1176 0.1634
Onchocerca volvulus 0.0125 0.0269 0.1045
Schistosoma mansoni lamin 0.0143 0.0316 0.042
Loa Loa (eye worm) hypothetical protein 0.047 0.1176 0.1176
Echinococcus multilocularis inositol monophosphatase 1 0.0109 0.0227 0.0316
Schistosoma mansoni calcium-activated potassium channel 0.0075 0.0137 0.017
Schistosoma mansoni norepinephrine/norepinephrine transporter 0.0031 0.0021 0.0009
Brugia malayi MH1 domain containing protein 0.0028 0.0013 0.0008
Echinococcus granulosus potassium voltage gated channel subfamily H 0.0028 0.0015 0.0021
Schistosoma mansoni transcription factor LCR-F1 0.0043 0.0055 0.0055
Mycobacterium tuberculosis Probable cytochrome P450 124 Cyp124 0.0063 0.0107 0.0209
Trichomonas vaginalis glucosylceramidase, putative 0.0175 0.0401 0.1301
Trichomonas vaginalis alpha-glucosidase, putative 0.0035 0.0033 0.0026
Schistosoma mansoni nicotinic acetylcholine receptor alpha 0.0055 0.0086 0.0099
Loa Loa (eye worm) acetylcholine receptor protein 0.0047 0.0065 0.0065
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.006 0.0099 0.0319
Trypanosoma brucei pyruvate kinase 1, putative 0.0035 0.0032 0.0007
Schistosoma mansoni lipoxygenase 0.0181 0.0415 0.0558
Mycobacterium tuberculosis Probable cytochrome P450 128 Cyp128 0.0063 0.0107 0.0209
Brugia malayi Dopamine receptor protein 2 0.047 0.1176 0.1171
Onchocerca volvulus 0.047 0.1176 0.4644
Loa Loa (eye worm) hypothetical protein 0.0031 0.0021 0.0021
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.047 0.1176 0.1634
Loa Loa (eye worm) hypothetical protein 0.0052 0.0076 0.0076
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0307 0.0747 0.2499
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0141 0.0312 0.0434
Plasmodium falciparum pyruvate kinase 0.0035 0.0032 0.0244
Brugia malayi Serotonin/octopamine receptor family protein 7 0.047 0.1176 0.1171
Brugia malayi MH2 domain containing protein 0.005 0.0073 0.0067
Schistosoma mansoni hypothetical protein 0.0063 0.0107 0.0128
Schistosoma mansoni tyrosyl-DNA phosphodiesterase 0.013 0.0283 0.0373
Brugia malayi Twik (KCNK-like) family of potasium channels, alpha subunit 40 0.0075 0.0137 0.0131
Echinococcus multilocularis pyruvate kinase 0.0028 0.0013 0.0018
Schistosoma mansoni neuropeptide receptor 0.047 0.1176 0.1617
Schistosoma mansoni ap endonuclease 0.0056 0.0088 0.0102
Loa Loa (eye worm) glutaminase 2 0.1131 0.2914 0.2914
Trichomonas vaginalis ap endonuclease, putative 0.0056 0.0088 0.0219
Schistosoma mansoni twik family of potassium channels-related 0.0075 0.0137 0.017
Schistosoma mansoni neuropeptide F-like receptor 0.047 0.1176 0.1617
Brugia malayi bHLH-PAS transcription factor 0.0038 0.004 0.0034
Brugia malayi nicotinic acetylcholine receptor beta-1 chain precursor 0.0103 0.0211 0.0205
Loa Loa (eye worm) hypothetical protein 0.047 0.1176 0.1176
Echinococcus granulosus cytochrome P450 2K1 0.0063 0.0107 0.0148
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.047 0.1176 0.1617
Echinococcus multilocularis mothers against decapentaplegic 5 0.005 0.0073 0.0101
Echinococcus multilocularis rhodopsin orphan GPCR 0.047 0.1176 0.1634
Onchocerca volvulus 0.0055 0.0086 0.0319
Echinococcus granulosus TGF beta signal transducer SmadC 0.005 0.0073 0.0101
Trypanosoma cruzi ion transport protein, putative 0.0075 0.0137 0.0114
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0307 0.0747 0.2499
Mycobacterium leprae Probable fructose bisphosphate aldolase Fba 0.015 0.0334 0.1954
Echinococcus multilocularis rhodopsin orphan GPCR 0.047 0.1176 0.1634
Loa Loa (eye worm) melatonin receptor type 1A 0.047 0.1176 0.1176
Plasmodium vivax GTP-binding nuclear protein RAN/TC4, putative 0.0043 0.0054 0.0541
Entamoeba histolytica peptidyl-prolyl cis-trans isomerase, putative 0.0032 0.0025 0.0076
Schistosoma mansoni Cys-loop ligand gated ion channel subunit 0.0103 0.0211 0.0273
Mycobacterium tuberculosis Probable fructose-bisphosphate aldolase Fba 0.015 0.0334 0.0679
Brugia malayi Tyrosyl-DNA phosphodiesterase family protein 0.013 0.0283 0.0277
Leishmania major hypothetical protein, conserved 0.0043 0.0055 0.0052
Echinococcus granulosus gamma aminobutyric acid receptor subunit 0.0047 0.0065 0.0091
Loa Loa (eye worm) hypothetical protein 0.0075 0.0137 0.0137
Echinococcus multilocularis twik family of potassium channels 0.0075 0.0137 0.0191
Onchocerca volvulus 0.0031 0.0021 0.0062
Echinococcus multilocularis carboxylesterase 5A 0.0069 0.0121 0.0168
Echinococcus multilocularis acetylcholinesterase 0.0069 0.0121 0.0168
Echinococcus granulosus endonuclease exonuclease phosphatase 0.0224 0.0531 0.0738
Mycobacterium tuberculosis Probable NADH dehydrogenase Ndh 0.0091 0.0178 0.0357
Loa Loa (eye worm) hypothetical protein 0.0075 0.0137 0.0137
Schistosoma mansoni alpha-galactosidase/alpha-n-acetylgalactosaminidase 0.0066 0.0115 0.0139
Toxoplasma gondii aminopeptidase N protein 0.0304 0.074 1
Loa Loa (eye worm) hypoxia-induced factor 1 0.0158 0.0356 0.0356
Loa Loa (eye worm) hypothetical protein 0.0031 0.0022 0.0022
Schistosoma mansoni nAChR subunit (ShAR1-beta2-like) 0.0103 0.0211 0.0273
Brugia malayi acetyltransferase, GNAT family protein 0.0433 0.1078 0.1073
Loa Loa (eye worm) hypothetical protein 0.0047 0.0065 0.0065
Schistosoma mansoni alpha glucosidase 0.0035 0.0033 0.0024
Onchocerca volvulus 0.0103 0.0211 0.0814
Leishmania major apurinic/apyrimidinic endonuclease-redox protein 0.0056 0.0088 0.0086
Schistosoma mansoni bromodomain-containing nuclear protein 1 brd1 0.0029 0.0016 0.0001
Loa Loa (eye worm) hypothetical protein 0.0035 0.0032 0.0032
Echinococcus multilocularis lysosomal alpha glucosidase 0.0158 0.0356 0.0495
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0085 0.0164 0.048
Echinococcus multilocularis TRP (transient receptor potential) channel 0.0044 0.0055 0.0076
Giardia lamblia Pyruvate kinase 0.0035 0.0032 0.0062
Mycobacterium tuberculosis Probable cytochrome P450 141 Cyp141 0.0063 0.0107 0.0209
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0103 0.0211 0.0205
Loa Loa (eye worm) hypothetical protein 0.0031 0.0022 0.0022
Trichomonas vaginalis glucosylceramidase, putative 0.0267 0.0642 0.2136
Echinococcus granulosus growth hormone secretagogue receptor type 1 0.047 0.1176 0.1634
Echinococcus multilocularis growth hormone secretagogue receptor type 1 0.047 0.1176 0.1634
Schistosoma mansoni amine GPCR 0.047 0.1176 0.1617
Loa Loa (eye worm) hypothetical protein 0.047 0.1176 0.1176
Leishmania major alpha glucosidase II subunit, putative 0.0035 0.0033 0.003
Loa Loa (eye worm) cytochrome P450 0.0063 0.0107 0.0107
Brugia malayi Transient-receptor-potential like protein 0.0044 0.0055 0.0049
Brugia malayi jmjC domain containing protein 0.0166 0.0378 0.0372
Loa Loa (eye worm) hypothetical protein 0.0075 0.0137 0.0137
Onchocerca volvulus 0.0091 0.0181 0.0694
Schistosoma mansoni alpha-galactosidase/alpha-n-acetylgalactosaminidase 0.0099 0.0202 0.026
Brugia malayi Calcitonin receptor-like protein seb-1 0.0154 0.0345 0.034
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0049 0.0069 0.0095
Mycobacterium ulcerans cytochrome P450 105Q4 Cyp105Q4 0.0063 0.0107 0.0347
Echinococcus granulosus orexin receptor type 2 0.047 0.1176 0.1634
Schistosoma mansoni Cys-loop ligand gated ion channel subunit 0.0103 0.0211 0.0273
Onchocerca volvulus 0.047 0.1176 0.4644
Brugia malayi latrophilin 2 splice variant baaae 0.0105 0.0217 0.0212
Loa Loa (eye worm) TWK-7 protein 0.0075 0.0137 0.0137
Echinococcus granulosus SAM and MBT domain containing protein 0.0054 0.0083 0.0115
Schistosoma mansoni calcium-activated potassium channel 0.1461 0.3781 0.5246
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0053 0.0079 0.0056
Loa Loa (eye worm) hypothetical protein 0.0075 0.0137 0.0137
Schistosoma mansoni twik family of potassium channels-related 0.0075 0.0137 0.017
Loa Loa (eye worm) 3-hydroxyacyl-CoA dehydrogenase type II 0.0056 0.0088 0.0088
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.0307 0.0747 0.2759
Mycobacterium ulcerans ATP-dependent Clp protease proteolytic subunit 0.0082 0.0156 0.0517
Echinococcus multilocularis glycine receptor subunit alpha 1 0.0103 0.0211 0.0293
Entamoeba histolytica glycosyl hydrolase, family 31 protein 0.0035 0.0033 0.0104
Schistosoma mansoni glucose-6-phosphate 1-dehydrogenase 0.0098 0.0198 0.0254
Toxoplasma gondii hypothetical protein 0.0031 0.0021 0.0256
Brugia malayi beta-lactamase 0.0074 0.0134 0.0129
Trypanosoma brucei ubiquitin carboxyl-terminal hydrolase, putative 0.0052 0.0076 0.0051
Loa Loa (eye worm) hypothetical protein 0.0103 0.021 0.021
Echinococcus multilocularis lysosomal alpha glucosidase 0.0158 0.0356 0.0495
Giardia lamblia Flap structure-specific endonuclease 0.0057 0.009 0.0277
Echinococcus granulosus uncharacterized sodium dependent transporter 0.0031 0.0021 0.003
Schistosoma mansoni coup transcription factor 0.0031 0.0022 0.001
Echinococcus multilocularis nAChR subunit 0.0055 0.0086 0.012
Brugia malayi Neurotransmitter-gated ion-channel transmembrane region family protein 0.0103 0.0211 0.0205
Loa Loa (eye worm) hypothetical protein 0.0066 0.0115 0.0115
Schistosoma mansoni P2X receptor subunit 0.0067 0.0116 0.0141
Echinococcus multilocularis multidrug and toxin extrusion protein 2 0.0033 0.0028 0.0039
Loa Loa (eye worm) mbt repeat family protein 0.0054 0.0083 0.0083
Plasmodium vivax flap endonuclease 1, putative 0.0057 0.009 0.1036
Trypanosoma cruzi Voltage-dependent calcium channel subunit, putative 0.0035 0.0033 0.0009
Brugia malayi photoreceptor-specific nuclear receptor 0.0031 0.0022 0.0016
Echinococcus granulosus neuropeptide receptor 0.047 0.1176 0.1634
Echinococcus multilocularis neuronal acetylcholine receptor subunit alpha 4 0.0103 0.0211 0.0293
Loa Loa (eye worm) hypothetical protein 0.0047 0.0065 0.0065
Onchocerca volvulus 0.0075 0.0137 0.0522
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0109 0.0227 0.0701
Echinococcus multilocularis transfer RNA-Lys 0.0038 0.004 0.0055
Echinococcus granulosus voltage dependent calcium channel 0.0035 0.0033 0.0045
Toxoplasma gondii GTP-binding nuclear protein ran/tc4 0.0043 0.0054 0.0697
Loa Loa (eye worm) TWK-28 protein 0.0075 0.0137 0.0137
Loa Loa (eye worm) hypothetical protein 0.0241 0.0574 0.0574
Echinococcus granulosus nAChR subunit 0.0103 0.0211 0.0293
Loa Loa (eye worm) hypothetical protein 0.2609 0.6801 0.6801
Brugia malayi Neurotransmitter-gated ion-channel transmembrane region family protein 0.0103 0.0211 0.0205
Echinococcus granulosus p2X purinoceptor 4 0.0067 0.0116 0.0161
Loa Loa (eye worm) hypothetical protein 0.0049 0.0069 0.0069
Trichomonas vaginalis glucosylceramidase, putative 0.0185 0.0426 0.1386
Onchocerca volvulus Alhambra homolog 0.0029 0.0016 0.0039
Loa Loa (eye worm) hypothetical protein 0.047 0.1176 0.1176
Onchocerca volvulus 0.0241 0.0574 0.2254
Echinococcus multilocularis GTP binding nuclear protein Ran 0.0043 0.0054 0.0075
Mycobacterium tuberculosis Probable pyruvate kinase PykA 0.0035 0.0032 0.0055
Loa Loa (eye worm) hypothetical protein 0.0047 0.0065 0.0065
Echinococcus granulosus hypothetical protein 0.047 0.1176 0.1634
Trypanosoma brucei calcium-activated potassium channel, putative 0.0075 0.0137 0.0112
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.047 0.1176 0.1634
Onchocerca volvulus Pyruvate kinase homolog 0.0035 0.0032 0.0106
Schistosoma mansoni multidrug resistance protein 0.0033 0.0028 0.0018
Echinococcus multilocularis nAChR subunit 0.0103 0.0211 0.0293
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0033 0.0028 0.0039
Echinococcus granulosus mothers against decapentaplegic 5 0.005 0.0073 0.0101
Loa Loa (eye worm) serotonin transporter b 0.0182 0.0418 0.0418
Echinococcus granulosus sodium and chloride dependent glycine 0.0031 0.0021 0.003
Schistosoma mansoni nAChR subunit (ShAR1-alpha-like) 0.0241 0.0574 0.0778
Loa Loa (eye worm) PHD-finger family protein 0.0029 0.0016 0.0016
Brugia malayi jmjC domain containing protein 0.0043 0.0055 0.0049
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0052 0.0076 0.0177
Echinococcus multilocularis mitogen activated protein kinase 0.0053 0.0079 0.011
Trypanosoma brucei JmjC domain, hydroxylase, putative 0.0043 0.0055 0.003
Leishmania major glucose-6-phosphate 1-dehydrogenase, putative 0.0098 0.0198 0.0195
Trypanosoma brucei Lanosterol 14-alpha demethylase 0.0063 0.0107 0.0082
Schistosoma mansoni flap endonuclease-1 0.0051 0.0075 0.0084
Brugia malayi Cation transporter family protein 0.0103 0.0211 0.0205
Mycobacterium ulcerans cytochrome P450 185A4 Cyp185A4 0.0117 0.0249 0.0837
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0141 0.0312 0.0414
Loa Loa (eye worm) hypothetical protein 0.0075 0.0137 0.0137
Schistosoma mansoni rhodopsin-like orphan GPCR 0.047 0.1176 0.1617
Schistosoma mansoni ap endonuclease 0.0056 0.0088 0.0102
Schistosoma mansoni hypothetical protein 0.0049 0.0069 0.0075
Echinococcus multilocularis voltage dependent calcium channel type d subunit 0.0085 0.0165 0.0229
Loa Loa (eye worm) large conductance calcium-activated potassium channel alpha subunit ai 0.0075 0.0137 0.0137
Echinococcus multilocularis allatostatin A receptor 0.047 0.1176 0.1634
Echinococcus granulosus small conductance calcium activated potassium 0.1647 0.4271 0.5938
Brugia malayi Twik (KCNK-like) family of potassium channels, alpha subunit 39A 0.0075 0.0137 0.0131
Brugia malayi G-protein coupled receptor 0.047 0.1176 0.1171
Trypanosoma brucei glucosidase, putative 0.0035 0.0033 0.0008
Loa Loa (eye worm) cytochrome P450 family protein 0.0143 0.0317 0.0317
Loa Loa (eye worm) hypothetical protein 0.0074 0.0134 0.0134
Echinococcus granulosus Polycystic kidney disease protein 0.0059 0.0095 0.0133
Schistosoma mansoni muscarinic acetylcholine (GAR) receptor 0.047 0.1176 0.1617
Brugia malayi Nuclear hormone receptor family member nhr-31 0.0031 0.0022 0.0016
Brugia malayi acetylcholine receptor alpha subunit precursor, putative 0.0103 0.0211 0.0205
Toxoplasma gondii transporter, cation channel family protein 0.0035 0.0033 0.0407
Schistosoma mansoni lamin 0.0143 0.0316 0.042
Echinococcus multilocularis isocitrate dehydrogenase 0.0033 0.0028 0.0039
Echinococcus multilocularis p2X purinoceptor 4 0.0067 0.0116 0.0161
Echinococcus multilocularis voltage dependent calcium channel 0.0085 0.0165 0.0229
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.0031 0.0022 0.0031
Brugia malayi 3-hydroxyacyl-CoA dehydrogenase type II 0.006 0.0099 0.0093
Echinococcus multilocularis alpha 1A adrenergic receptor 0.047 0.1176 0.1634
Echinococcus granulosus rhodopsin orphan GPCR 0.047 0.1176 0.1634
Brugia malayi Twik (KCNK-like) family of potassium channels, alpha subunit 5 0.0075 0.0137 0.0131
Loa Loa (eye worm) hypothetical protein 0.0125 0.0269 0.0269
Echinococcus multilocularis sodium dependent neurotransmitter transporter 0.0031 0.0021 0.003
Brugia malayi hypothetical protein 0.047 0.1176 0.1171
Echinococcus multilocularis nicotinic acetylcholine receptor alpha subunit 0.024 0.0572 0.0795
Mycobacterium ulcerans putative regulatory protein 0.0038 0.004 0.0117
Echinococcus multilocularis beta LACTamase domain containing family member 0.0074 0.0134 0.0187
Echinococcus multilocularis glycine receptor subunit alpha 1 0.0103 0.0211 0.0293
Loa Loa (eye worm) hypothetical protein 0.0047 0.0065 0.0065
Onchocerca volvulus 0.0074 0.0134 0.051
Trypanosoma cruzi JmjC domain, hydroxylase, putative 0.0043 0.0055 0.0032
Mycobacterium tuberculosis Probable cytochrome P450 137 Cyp137 0.0063 0.0107 0.0209
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.047 0.1176 0.1634
Echinococcus multilocularis ubiquitin specific protease 41 0.0052 0.0076 0.0106
Schistosoma mansoni thyroid hormone receptor 0.0031 0.0022 0.001
Echinococcus multilocularis thyroid hormone receptor alpha 0.0031 0.0022 0.0031
Loa Loa (eye worm) hypothetical protein 0.0075 0.0137 0.0137
Brugia malayi Intermediate filament tail domain containing protein 0.0143 0.0316 0.0311
Schistosoma mansoni hypothetical protein 0.034 0.0835 0.1142
Loa Loa (eye worm) hypothetical protein 0.0031 0.0021 0.0021
Brugia malayi Carboxylesterase family protein 0.0069 0.0121 0.0115
Schistosoma mansoni hypothetical protein 0.047 0.1176 0.1617
Schistosoma mansoni inositol monophosphatase 0.0109 0.0227 0.0296
Schistosoma mansoni twik family of potassium channels-related 0.0075 0.0137 0.017
Echinococcus multilocularis pyroglutamylated rfamide peptide receptor 0.047 0.1176 0.1634
Loa Loa (eye worm) hypothetical protein 0.0691 0.1757 0.1757
Onchocerca volvulus 0.0143 0.0316 0.1233
Trypanosoma brucei membrane transporter protein, putative 0.0033 0.0028 0.0003
Mycobacterium tuberculosis NAD(P)H quinone reductase LpdA 0.0101 0.0205 0.0412
Mycobacterium ulcerans glucose-6-phosphate 1-dehydrogenase 0.0064 0.0108 0.0353
Schistosoma mansoni hypothetical protein 0.0047 0.0063 0.0067
Onchocerca volvulus Glucosylceramidase homolog 0.0175 0.0401 0.1568
Schistosoma mansoni ran 0.0043 0.0054 0.0054
Trypanosoma brucei membrane transporter protein, putative 0.0033 0.0028 0.0003
Loa Loa (eye worm) hypothetical protein 0.0024 0.0003 0.0003
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0043 0.0055 0.0076
Schistosoma mansoni alpha-galactosidase/alpha-n-acetylgalactosaminidase 0.0099 0.0202 0.026
Mycobacterium tuberculosis Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras 0.0101 0.0205 0.0412
Loa Loa (eye worm) hypothetical protein 0.0075 0.0137 0.0137
Brugia malayi Nuclear hormone receptor family member nhr-49 0.0031 0.0022 0.0016
Loa Loa (eye worm) neuropeptide F receptor 0.047 0.1176 0.1176
Brugia malayi nicotinic acetylcholine receptor alpha subunit, putative 0.024 0.0572 0.0567
Echinococcus granulosus rhodopsin orphan GPCR 0.047 0.1176 0.1634
Brugia malayi glutathione reductase 0.004 0.0045 0.0039
Mycobacterium ulcerans pyruvate kinase 0.0035 0.0032 0.0092
Trypanosoma brucei membrane transporter protein, putative 0.0033 0.0028 0.0003
Brugia malayi hypoxia-induced factor 1 0.0158 0.0356 0.035
Trypanosoma cruzi peptidyl-prolyl cis-trans isomerase 0.0032 0.0025 0.0002
Chlamydia trachomatis glucose-6-phosphate 1-dehydrogenase 0.0098 0.0198 0.8133
Onchocerca volvulus 0.047 0.1176 0.4644
Echinococcus multilocularis TGF beta signal transducer SmadC 0.005 0.0073 0.0101
Echinococcus multilocularis sex peptide receptor 0.047 0.1176 0.1634
Loa Loa (eye worm) Smad1 0.005 0.0073 0.0073
Echinococcus multilocularis survival motor neuron protein 1 0.0229 0.0544 0.0756
Echinococcus multilocularis dnaJ subfamily B 0.0835 0.2137 0.2971
Brugia malayi putative neuropeptide receptor 0.047 0.1176 0.1171
Entamoeba histolytica hypothetical protein 0.0043 0.0055 0.0186
Loa Loa (eye worm) glycosyl hydrolase family 31 protein 0.0158 0.0356 0.0356
Giardia lamblia Endonuclease/Exonuclease/phosphatase 0.0056 0.0088 0.0271
Trypanosoma cruzi PAB1-binding protein , putative 0.0103 0.021 0.0187
Schistosoma mansoni rhodopsin-like orphan GPCR 0.047 0.1176 0.1617
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0031 0.0021 0.0016
Echinococcus granulosus TRP transient receptor potential channel 0.0044 0.0055 0.0076
Schistosoma mansoni Tr4/Tr2 (homologue) 0.0031 0.0022 0.001
Trichomonas vaginalis glucosylceramidase, putative 0.0267 0.0642 0.2136
Loa Loa (eye worm) hypothetical protein 0.0229 0.0544 0.0544
Onchocerca volvulus 0.047 0.1176 0.4644
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.0056 0.0088 0.0065
Echinococcus multilocularis neuropeptide s receptor 0.047 0.1176 0.1634
Echinococcus granulosus polycomb protein SCMH1 0.0054 0.0083 0.0115
Schistosoma mansoni hypothetical protein 0.1912 0.4969 0.6901
Schistosoma mansoni peptide (FMRFamide/neurokinin-3)-like receptor 0.047 0.1176 0.1617
Echinococcus multilocularis biogenic amine (5HT) receptor 0.0861 0.2205 0.3065
Echinococcus multilocularis serotonin receptor 0.2151 0.5598 0.7781
Plasmodium vivax ATP-dependent Clp protease proteolytic subunit, putative 0.0082 0.0156 0.195
Brugia malayi Isocitrate dehydrogenase 0.0033 0.0028 0.0022
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0103 0.0211 0.0205
Trichomonas vaginalis penicillin-binding protein, putative 0.0074 0.0134 0.0379
Trypanosoma cruzi hypothetical protein, conserved 0.0033 0.0028 0.0005
Loa Loa (eye worm) hypothetical protein 0.0075 0.0137 0.0137
Trypanosoma cruzi flap endonuclease-1 (FEN-1), putative 0.0057 0.009 0.0067
Loa Loa (eye worm) hypothetical protein 0.0074 0.0134 0.0134
Echinococcus granulosus phd:f box containing protein 0.0043 0.0055 0.0076
Schistosoma mansoni sodium/chloride dependent transporter 0.0182 0.0418 0.0561
Echinococcus multilocularis rhodopsin orphan GPCR 0.047 0.1176 0.1634
Brugia malayi Probable ClpP-like protease 0.0082 0.0156 0.015
Echinococcus multilocularis SAM and MBT domain containing protein 0.0054 0.0083 0.0115
Echinococcus granulosus nicotinic acetylcholine receptor alpha subunit 0.024 0.0572 0.0795
Trichomonas vaginalis glucosylceramidase, putative 0.0267 0.0642 0.2136
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.0031 0.0022 0.001
Echinococcus granulosus Alpha N acetylgalactosaminidase 0.0099 0.0202 0.028
Mycobacterium leprae conserved hypothetical protein 0.0074 0.0134 0.0765
Loa Loa (eye worm) hypothetical protein 0.0105 0.0217 0.0217
Loa Loa (eye worm) cytochrome P450 family protein 0.0117 0.0249 0.0249
Echinococcus granulosus FTZ F1 alpha 0.0031 0.0022 0.0031
Loa Loa (eye worm) hypothetical protein 0.047 0.1176 0.1176
Loa Loa (eye worm) hypothetical protein 0.0075 0.0137 0.0137
Echinococcus granulosus p2X purinoceptor 4 0.0067 0.0116 0.0161
Schistosoma mansoni nAChR subunit 0.0103 0.0211 0.0273
Loa Loa (eye worm) hypothetical protein 0.047 0.1176 0.1176
Echinococcus multilocularis Transcription factor, JmjC domain containing protein 0.0222 0.0525 0.0729
Giardia lamblia Ubiquitin carboxyl-terminal hydrolase 4 0.0052 0.0076 0.0226
Schistosoma mansoni voltage-gated cation channel 0.0085 0.0165 0.0209
Loa Loa (eye worm) hypothetical protein 0.0182 0.0418 0.0418
Mycobacterium tuberculosis Probable cytochrome P450 132 Cyp132 0.0063 0.0107 0.0209
Schistosoma mansoni hypothetical protein 0.0049 0.0069 0.0075
Brugia malayi Pin1-type peptidyl-prolyl cis-trans isomerase, BmPin1 0.0033 0.0027 0.0021
Echinococcus granulosus potassium channel subfamily K 0.0075 0.0137 0.0191
Loa Loa (eye worm) hypothetical protein 0.0075 0.0137 0.0137
Mycobacterium leprae RECA PROTEIN (RECOMBINASE A) [CONTAINS: Mle RECA INTEIN]. 0.0113 0.0238 0.1382
Onchocerca volvulus 0.0074 0.0134 0.051
Brugia malayi F/Y-rich N-terminus family protein 0.0032 0.0024 0.0018
Brugia malayi Doublecortin family protein 0.0059 0.0095 0.009
Schistosoma mansoni biogenic amine receptor 0.047 0.1176 0.1617
Schistosoma mansoni sodium-dependent amino acid transporter 0.0031 0.0021 0.0009
Plasmodium vivax potassium channel, putative 0.0075 0.0137 0.1688
Loa Loa (eye worm) hypothetical protein 0.0028 0.0013 0.0013
Schistosoma mansoni hypothetical protein 0.047 0.1176 0.1617
Brugia malayi glutaminase DH11.1 0.1131 0.2914 0.291
Schistosoma mansoni biogenic amine (5HT) receptor 0.0861 0.2205 0.3051
Plasmodium falciparum M1-family alanyl aminopeptidase 0.0304 0.074 1
Brugia malayi Pre-SET motif family protein 0.0125 0.0269 0.0263
Loa Loa (eye worm) hypothetical protein 0.047 0.1176 0.1176
Toxoplasma gondii histone lysine methyltransferase SET1 0.0126 0.0272 0.3658
Schistosoma mansoni sodium/chloride dependent transporter 0.0031 0.0021 0.0009
Brugia malayi hypothetical protein 0.0047 0.0065 0.0059
Echinococcus multilocularis somatostatin receptor 0.047 0.1176 0.1634
Mycobacterium tuberculosis Probable cytochrome P450 143 Cyp143 0.0063 0.0107 0.0209
Echinococcus multilocularis orexin receptor type 2 0.047 0.1176 0.1634
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0074 0.0134 0.0166
Echinococcus granulosus potassium channel subfamily K 8 0.0075 0.0137 0.0191
Trypanosoma brucei mitogen activated protein kinase 4, putative 0.0053 0.0079 0.0054
Schistosoma mansoni norepinephrine/norepinephrine transporter 0.0031 0.0021 0.0009
Schistosoma mansoni calcium-activated potassium channel 0.1647 0.4271 0.5929
Echinococcus granulosus g-protein coupled receptor 0.047 0.1176 0.1634
Mycobacterium ulcerans cytochrome P450 126A3 Cyp126A3 0.0063 0.0107 0.0347
Schistosoma mansoni norepinephrine/norepinephrine transporter 0.0182 0.0418 0.0561
Mycobacterium ulcerans ATP-dependent Clp protease proteolytic subunit 0.0082 0.0156 0.0517
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0182 0.0418 0.0412
Trypanosoma cruzi JmjC domain, hydroxylase, putative 0.0043 0.0055 0.0032
Schistosoma mansoni twik family of potassium channels-related 0.0075 0.0137 0.017
Plasmodium falciparum glutathione reductase 0.004 0.0045 0.0414
Mycobacterium ulcerans cytochrome P450 108B4 Cyp108B4 0.0063 0.0107 0.0347
Brugia malayi hypothetical protein 0.0103 0.021 0.0204
Brugia malayi G protein-coupled receptor F59B2.13 0.047 0.1176 0.1171
Echinococcus granulosus pyruvate kinase 0.0035 0.0032 0.0045
Brugia malayi hypothetical protein 0.0047 0.0065 0.0059
Echinococcus granulosus alpha 1A adrenergic receptor 0.047 0.1176 0.1634
Mycobacterium tuberculosis Conserved protein 0.0074 0.0134 0.0266
Schistosoma mansoni amine GPCR 0.0849 0.2174 0.3007
Plasmodium vivax hypothetical protein, conserved 0.0029 0.0016 0.0013
Echinococcus multilocularis potassium channel subfamily K 8 0.0075 0.0137 0.0191
Schistosoma mansoni neurotransmitter gated ion channel 0.0047 0.0065 0.007
Plasmodium falciparum ataxin-2 like protein, putative 0.0103 0.021 0.2692
Echinococcus multilocularis atpase aaa+ type core atpase aaa type core 0.2617 0.6821 0.9482
Loa Loa (eye worm) hypothetical protein 0.047 0.1176 0.1176
Giardia lamblia Hypothetical protein 0.0075 0.0137 0.0453
Echinococcus multilocularis 0.0063 0.0107 0.0148
Toxoplasma gondii PHD-finger domain-containing protein 0.0029 0.0016 0.0178
Loa Loa (eye worm) hypothetical protein 0.0024 0.0005 0.0005
Toxoplasma gondii ATP-dependent Clp endopeptidase, proteolytic subunit ClpP domain-containing protein 0.0082 0.0156 0.2082
Echinococcus multilocularis glycine receptor subunit beta 0.0103 0.0211 0.0293
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.0031 0.0022 0.0031
Treponema pallidum fructose-bisphosphate aldolase 0.0307 0.0747 1
Loa Loa (eye worm) hypothetical protein 0.0047 0.0065 0.0065
Mycobacterium tuberculosis Conserved protein 0.0074 0.0134 0.0266
Loa Loa (eye worm) hypothetical protein 0.0075 0.0137 0.0137
Loa Loa (eye worm) G-protein coupled receptor 0.047 0.1176 0.1176
Echinococcus granulosus Jumonji AT rich interactive domain 1B 0.0047 0.0063 0.0088
Echinococcus granulosus potassium voltage gated channel subfamily H 0.0082 0.0157 0.0218
Plasmodium falciparum LCCL domain-containing protein 0.0059 0.0095 0.1112
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.0047 0.0063 0.0058
Trypanosoma cruzi trypanothione reductase, putative 0.004 0.0045 0.0022
Schistosoma mansoni P2X receptor subunit 0.0067 0.0116 0.0141
Loa Loa (eye worm) hypothetical protein 0.0069 0.0122 0.0122
Trypanosoma cruzi mitogen activated protein kinase 2, putative 0.0053 0.0079 0.0056
Schistosoma mansoni hypothetical protein 0.0049 0.0069 0.0075
Echinococcus granulosus potassium channel subfamily K 8 0.0075 0.0137 0.0191
Echinococcus multilocularis peregrin 0.0039 0.0044 0.006
Echinococcus granulosus 7TM GPCR rhodopsin 0.047 0.1176 0.1634
Schistosoma mansoni gcn5proteinral control of amino-acid synthesis 5-like 2 gcnl2 0.0433 0.1078 0.1481
Loa Loa (eye worm) hypothetical protein 0.0031 0.0021 0.0021
Plasmodium vivax amine transporter, putative 0.0031 0.0021 0.0093
Mycobacterium leprae Conserved hypothetical protein 0.0063 0.0107 0.06
Loa Loa (eye worm) hypothetical protein 0.0024 0.0003 0.0003
Mycobacterium tuberculosis Probable dehydrogenase 0.0091 0.0178 0.0357
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0031 0.0022 0.0031
Echinococcus granulosus peptide allatostatin:somatostatin 0.047 0.1176 0.1634
Loa Loa (eye worm) hypothetical protein 0.0031 0.0021 0.0021
Brugia malayi steroid hormone receptor 0.0031 0.0022 0.0016
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0141 0.0312 0.0434
Leishmania major trypanothione reductase 0.004 0.0045 0.0042
Schistosoma mansoni sex comb on midleg homolog 0.0054 0.0083 0.0094
Brugia malayi Acetylcholine receptor protein, alpha-like chain 1 precursor 0.0047 0.0065 0.0059
Loa Loa (eye worm) hypothetical protein 0.0112 0.0234 0.0234
Echinococcus granulosus g protein coupled receptor 0.047 0.1176 0.1634
Echinococcus granulosus smad 0.005 0.0073 0.0101
Echinococcus multilocularis Jumonji, AT rich interactive domain 1B 0.0047 0.0063 0.0088
Loa Loa (eye worm) glycosyl hydrolase family 31 protein 0.0035 0.0033 0.0033
Schistosoma mansoni histamine-responsive GPCR (AAF21638) 0.047 0.1176 0.1617
Mycobacterium tuberculosis Probable membrane NADH dehydrogenase NdhA 0.0091 0.0178 0.0357
Brugia malayi gamma-aminobutyric-acid receptor beta subunit precursor 0.0103 0.0211 0.0205
Onchocerca volvulus Dopamine\/Ecdysteroid receptor homolog 0.047 0.1176 0.4644
Loa Loa (eye worm) hypothetical protein 0.047 0.1176 0.1176
Echinococcus multilocularis importin subunit beta 1 0.0059 0.0095 0.0132
Schistosoma mansoni twik family of potassium channels-related 0.0075 0.0137 0.017
Onchocerca volvulus 0.047 0.1176 0.4644
Entamoeba histolytica DNA repair and recombination protein RAD52, putative 0.1048 0.2695 1
Schistosoma mansoni ancient conserved domain protein 2 (cyclin m2) 0.047 0.1176 0.1617
Treponema pallidum sodium- and chloride- dependent transporter 0.0182 0.0418 0.5508
Schistosoma mansoni smad1 5 8 and 0.005 0.0073 0.008
Trypanosoma cruzi glucose-6-phosphate 1-dehydrogenase, putative 0.0032 0.0026 0.0002
Echinococcus multilocularis lamin dm0 0.0143 0.0316 0.044
Onchocerca volvulus 0.0059 0.0095 0.0356
Brugia malayi hypothetical protein 0.047 0.1176 0.1171
Brugia malayi Tachykinin-like peptides receptor 99D 0.047 0.1176 0.1171
Echinococcus multilocularis calcium activated potassium channel variant 0.0075 0.0137 0.0191
Schistosoma mansoni rab6-interacting 0.0059 0.0095 0.0112
Trypanosoma cruzi apurinic/apyrimidinic endonuclease 0.0056 0.0088 0.0065
Brugia malayi Dopamine receptor protein 1 0.2609 0.6801 0.6799
Onchocerca volvulus 0.0075 0.0137 0.0522
Schistosoma mansoni Cys-loop ligand gated ion channel subunit 0.0103 0.0211 0.0273
Schistosoma mansoni retinoic acid receptor RXR 0.0031 0.0022 0.001
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.0031 0.0022 0.0022
Trypanosoma brucei isocitrate dehydrogenase, putative 0.0033 0.0028 0.0003
Echinococcus granulosus survival motor neuron protein 1 0.0229 0.0544 0.0756
Loa Loa (eye worm) hypothetical protein 0.047 0.1176 0.1176
Leishmania major mitogen activated protein kinase, putative,map kinase, putative 0.0053 0.0079 0.0076
Brugia malayi MAP kinase sur-1 0.0053 0.0079 0.0074
Loa Loa (eye worm) hypothetical protein 0.0059 0.0095 0.0095
Plasmodium falciparum potassium channel 0.0075 0.0137 0.1688
Echinococcus granulosus jumonji domain containing protein 0.004 0.0045 0.0063
Loa Loa (eye worm) glucose-6-phosphate dehydrogenase 0.0098 0.0198 0.0198
Echinococcus multilocularis smad 0.005 0.0073 0.0101
Mycobacterium ulcerans hypothetical protein 0.0147 0.0328 0.1108
Echinococcus multilocularis neuropeptide Y receptor 0.047 0.1176 0.1634
Schistosoma mansoni biogenic amine receptor 0.047 0.1176 0.1617
Schistosoma mansoni transient receptor potential channel 0.0071 0.0127 0.0156
Onchocerca volvulus 0.047 0.1176 0.4644
Onchocerca volvulus 0.0241 0.0574 0.2254
Schistosoma mansoni rotamase 0.0033 0.0027 0.0017
Schistosoma mansoni thyroid hormone receptor 0.0031 0.0022 0.001
Brugia malayi hypothetical protein 0.047 0.1176 0.1171
Brugia malayi Twik (KCNK-like) family of potassium channels, alpha subunit 30. 0.0075 0.0137 0.0131
Echinococcus multilocularis neuropeptides capa receptor 0.047 0.1176 0.1634
Trichomonas vaginalis glucosylceramidase, putative 0.0267 0.0642 0.2136
Loa Loa (eye worm) hypothetical protein 0.0075 0.0137 0.0137
Mycobacterium tuberculosis Probable replicative DNA helicase DnaB 0.1751 0.4544 0.9384
Mycobacterium leprae ATP-dependent Clp protease proteolytic subunit 1 0.0028 0.0015 0.0053
Onchocerca volvulus Protein ultraspiracle homolog 0.0031 0.0022 0.0065
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0074 0.0134 0.0166
Brugia malayi RE15519p 0.047 0.1176 0.1171
Schistosoma mansoni hypothetical protein 0.0049 0.0069 0.0075
Brugia malayi Voltage-gated calcium channel, L-type, alpha subunit. C. elegans egl-19 ortholog 0.0085 0.0165 0.0159
Mycobacterium ulcerans cytochrome P450 142A3 Cyp142A3 0.0063 0.0107 0.0347
Loa Loa (eye worm) hypothetical protein 0.0343 0.0841 0.0841
Loa Loa (eye worm) hypothetical protein 0.0103 0.0212 0.0212
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0031 0.0022 0.001
Trypanosoma cruzi cytochrome p450-like protein, putative 0.0063 0.0107 0.0084
Schistosoma mansoni rhodopsin-like orphan GPCR 0.047 0.1176 0.1617
Entamoeba histolytica myo-inositol monophosphatase, putative 0.0109 0.0227 0.0828
Loa Loa (eye worm) hypothetical protein 0.0103 0.0211 0.0211
Echinococcus multilocularis rhodopsin orphan GPCR 0.047 0.1176 0.1634
Schistosoma mansoni neuropeptide receptor 0.047 0.1176 0.1617
Echinococcus multilocularis 3 hydroxyacyl coenzyme A dehydrogenase type 2 0.006 0.0099 0.0137
Echinococcus granulosus allatostatin A receptor 0.047 0.1176 0.1634
Echinococcus granulosus GTP binding nuclear protein Ran 0.0043 0.0054 0.0075
Brugia malayi hypothetical protein 0.047 0.1176 0.1171
Brugia malayi hypothetical protein 0.0059 0.0095 0.009
Schistosoma mansoni peptidase Clp (S14 family) 0.0082 0.0156 0.0197
Echinococcus granulosus rhodopsin orphan GPCR 0.047 0.1176 0.1634
Echinococcus multilocularis ATP dependent Clp protease proteolytic subunit 0.0082 0.0156 0.0217
Mycobacterium ulcerans cytochrome P450 51B1 Cyp51B1 0.0063 0.0107 0.0347
Loa Loa (eye worm) hypothetical protein 0.047 0.1176 0.1176
Brugia malayi C2-HC type zinc finger protein C.e-MyT1 0.0062 0.0102 0.0096
Brugia malayi hypothetical protein 0.0043 0.0055 0.0049
Mycobacterium ulcerans cytochrome P450 150A6 Cyp150A6 0.0063 0.0107 0.0347
Trypanosoma cruzi importin beta-1 subunit, putative 0.0048 0.0066 0.0043
Echinococcus multilocularis gamma aminobutyric acid receptor subunit 0.0047 0.0065 0.0091
Chlamydia trachomatis ATP-dependent Clp protease proteolytic subunit 0.0082 0.0156 0.6217
Echinococcus multilocularis pyruvate kinase 0.0035 0.0032 0.0045
Loa Loa (eye worm) voltage-dependent calcium channel 0.0035 0.0033 0.0033
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.0074 0.0134 0.0442
Loa Loa (eye worm) hypothetical protein 0.0055 0.0086 0.0086
Mycobacterium tuberculosis Putative ferredoxin reductase 0.0091 0.0178 0.0357
Trypanosoma cruzi hypothetical protein, conserved 0.0075 0.0137 0.0114
Chlamydia trachomatis recombinase RecA 0.0113 0.0238 1
Onchocerca volvulus 0.0075 0.0137 0.0522
Loa Loa (eye worm) hypothetical protein 0.0075 0.0137 0.0137
Schistosoma mansoni opsin-like receptor 0.047 0.1176 0.1617
Plasmodium falciparum histone acetyltransferase GCN5 0.0117 0.0247 0.3203
Schistosoma mansoni jumonji domain containing protein 0.0203 0.0474 0.0639
Brugia malayi Cytochrome P450 family protein 0.0143 0.0317 0.0312
Brugia malayi Thioredoxin reductase 0.004 0.0045 0.0039
Trypanosoma cruzi DNA repair protein, putative 0.0035 0.0032 0.0009
Loa Loa (eye worm) CYP4Cod1 0.0117 0.0249 0.0249
Leishmania major tyrosyl-DNA phosphodiesterase 1 0.013 0.0283 0.028
Giardia lamblia GTP-binding nuclear protein RAN/TC4 0.0043 0.0054 0.0143
Schistosoma mansoni microtubule-associated protein tau 0.2758 0.7194 1
Echinococcus granulosus peptidase Clp S14 family 0.0054 0.0082 0.0114
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0074 0.0134 0.0129
Echinococcus multilocularis peptide (allatostatin:somatostatin) 0.047 0.1176 0.1634
Entamoeba histolytica acetyltransferase, GNAT family 0.0117 0.0247 0.0901
Echinococcus granulosus g protein coupled receptor 0.047 0.1176 0.1634
Brugia malayi cytochrome P450 0.0063 0.0107 0.0101
Leishmania major myo-inositol-1(or 4)-monophosphatase 1, putative 0.0109 0.0227 0.0225
Loa Loa (eye worm) hypothetical protein 0.0031 0.0022 0.0022
Echinococcus granulosus dro:myosuppressin receptor 0.047 0.1176 0.1634
Giardia lamblia Histone acetyltransferase GCN5 0.0117 0.0247 0.0864
Brugia malayi hypothetical protein 0.0229 0.0544 0.0538
Trypanosoma cruzi glucose-6-phosphate 1-dehydrogenase, putative 0.0098 0.0198 0.0175
Plasmodium vivax pyruvate kinase, putative 0.0035 0.0032 0.0244
Echinococcus granulosus intermediate filament protein 0.0143 0.0316 0.044
Brugia malayi Cation transporter family protein 0.0103 0.0211 0.0205
Loa Loa (eye worm) hypothetical protein 0.0043 0.0055 0.0055
Trypanosoma brucei isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0033 0.0028 0.0003
Brugia malayi CXXC zinc finger family protein 0.0059 0.0095 0.0089
Brugia malayi Importin beta-1 subunit 0.0059 0.0095 0.0089
Loa Loa (eye worm) hypothetical protein 0.006 0.0097 0.0097
Mycobacterium leprae PROBABLE ADENOSYLMETHIONINE-8-AMINO-7-OXONONANOATE AMINOTRANSFERASE BIOA 0.0147 0.0328 0.1917
Toxoplasma gondii melibiase subfamily protein 0.0099 0.0202 0.2699
Trichomonas vaginalis D-aminoacylase, putative 0.0074 0.0134 0.0379
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0035 0.0033 0.0026
Toxoplasma gondii aminopeptidase N, putative 0.0304 0.074 1
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0154 0.0345 0.0345
Brugia malayi Twik (KCNK-like) family of potassium channels, alpha subunit 35 0.0075 0.0137 0.0131
Echinococcus granulosus transient receptor potential gamma protein 0.0103 0.0212 0.0294
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0052 0.0076 0.0053
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 8 0.0052 0.0076 0.0106
Mycobacterium ulcerans cytochrome P450 124A1, Cyp124A1 0.0063 0.0107 0.0347
Schistosoma mansoni amine GPCR 0.047 0.1176 0.1617
Trichomonas vaginalis CMGC family protein kinase 0.0053 0.0079 0.0188
Mycobacterium tuberculosis Probable cytochrome P450 125 Cyp125 0.0063 0.0107 0.0209
Echinococcus multilocularis Two pore potassium channel protein sup 9 0.0075 0.0137 0.0191
Loa Loa (eye worm) isocitrate dehydrogenase 0.0033 0.0028 0.0028
Brugia malayi glutamate-gated chloride channel alpha3A subunit, putative 0.0055 0.0086 0.008
Loa Loa (eye worm) hypothetical protein 0.047 0.1176 0.1176
Toxoplasma gondii cytochrome p450 superfamily protein 0.0063 0.0107 0.1411
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0129 0.0279 0.0368
Loa Loa (eye worm) hypothetical protein 0.0072 0.013 0.013
Schistosoma mansoni importin beta-1 0.0059 0.0095 0.0111
Plasmodium falciparum transporter, putative 0.0031 0.0021 0.0093
Loa Loa (eye worm) LGC-31 protein 0.0103 0.0211 0.0211
Schistosoma mansoni protein phosphatase 2C 0.0043 0.0055 0.0055
Loa Loa (eye worm) CXXC zinc finger family protein 0.0059 0.0095 0.0095
Echinococcus multilocularis gcn5proteinral control of amino acid synthesis 0.0433 0.1078 0.1499
Plasmodium vivax ataxin-2 like protein, putative 0.0103 0.021 0.2692
Loa Loa (eye worm) glutathione reductase 0.004 0.0045 0.0045
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.0074 0.0134 0.0266
Echinococcus granulosus lysine specific demethylase 6a 0.0043 0.0055 0.0076
Brugia malayi PAS domain containing protein 0.0051 0.0075 0.0069
Toxoplasma gondii ion channel protein 0.0075 0.0137 0.1825
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0052 0.0076 0.0053
Echinococcus granulosus serotonin transporter 0.0182 0.0418 0.0581
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0125 0.0269 0.0374
Schistosoma mansoni RAR-like nuclear receptor 0.0031 0.0022 0.001
Echinococcus granulosus nicotinic acetylcholine receptor subunit alpha 8 0.024 0.0572 0.0795
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0031 0.0021 0.0016
Onchocerca volvulus 0.047 0.1176 0.4644
Trypanosoma brucei importin beta-1 subunit, putative 0.0059 0.0095 0.007
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.0143 0.0316 0.0316
Schistosoma mansoni amine GPCR 0.047 0.1176 0.1617
Plasmodium vivax glutathione reductase, putative 0.004 0.0045 0.0414
Trypanosoma brucei Voltage-dependent calcium channel subunit, putative 0.0035 0.0033 0.0008
Schistosoma mansoni hypothetical protein 0.1647 0.4271 0.5929
Echinococcus granulosus neuropeptide FF receptor 2 0.047 0.1176 0.1634
Mycobacterium tuberculosis Probable esterase LipL 0.0074 0.0134 0.0266
Onchocerca volvulus 0.047 0.1176 0.4644
Loa Loa (eye worm) glutamate-gated chloride channel alpha3A subunit 0.0103 0.0211 0.0211
Echinococcus multilocularis neuropeptide FF receptor 2 0.047 0.1176 0.1634
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0049 0.0069 0.0095
Leishmania major pyruvate kinase 0.0035 0.0032 0.003
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0109 0.0227 0.0205
Loa Loa (eye worm) hypothetical protein 0.0103 0.0211 0.0211
Echinococcus granulosus g protein coupled receptor 0.047 0.1176 0.1634
Loa Loa (eye worm) hypothetical protein 0.0103 0.0211 0.0211
Onchocerca volvulus Huntingtin homolog 0.012 0.0256 0.0992
Echinococcus granulosus mitogen activated protein kinase 0.0053 0.0079 0.011
Schistosoma mansoni sodium/chloride dependent neurotransmitter transporter 0.0031 0.0021 0.0009
Leishmania major hypothetical protein, conserved 0.0033 0.0028 0.0025
Schistosoma mansoni twik family of potassium channels-related 0.0075 0.0137 0.017
Echinococcus granulosus apoptotic protease activating factor 1 0.0082 0.0155 0.0216
Brugia malayi Cytochrome P450 family protein 0.0117 0.0249 0.0244
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0125 0.0269 0.0374
Trichomonas vaginalis inositol monophosphatase, putative 0.0109 0.0227 0.0701
Schistosoma mansoni voltage-gated potassium channel 0.0089 0.0175 0.0223
Plasmodium vivax M1-family alanyl aminopeptidase, putative 0.0304 0.074 1
Entamoeba histolytica acyl-CoA synthetase, putative 0.0025 0.0006 0.0005
Schistosoma mansoni neurotransmitter gated ion channel 0.0055 0.0086 0.0099
Trichomonas vaginalis cat eye syndrome critical region protein 2, cscr2, putative 0.0127 0.0275 0.0865
Echinococcus granulosus pyruvate kinase 0.0035 0.0032 0.0045
Loa Loa (eye worm) hypothetical protein 0.0075 0.0137 0.0137
Echinococcus granulosus acetylcholine receptor subunit beta 1 0.0103 0.0211 0.0293
Loa Loa (eye worm) hypothetical protein 0.047 0.1176 0.1176
Schistosoma mansoni single-minded 0.0051 0.0075 0.0083
Loa Loa (eye worm) hypothetical protein 0.0047 0.0065 0.0065
Trypanosoma cruzi isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0033 0.0028 0.0005
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0075 0.0137 0.0388
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0141 0.0312 0.0414
Trichomonas vaginalis CMGC family protein kinase 0.0053 0.0079 0.0188
Trichomonas vaginalis glucosylceramidase, putative 0.0185 0.0426 0.1386
Echinococcus granulosus tachykinin peptides receptor 99D 0.047 0.1176 0.1634
Plasmodium vivax thioredoxin reductase, putative 0.004 0.0045 0.0414
Loa Loa (eye worm) hypothetical protein 0.047 0.1176 0.1176
Schistosoma mansoni ubiquitously transcribed sex (X/Y) chromosome tetratricopeptide repeat protein-related 0.0043 0.0055 0.0055
Leishmania major importin beta-1 subunit, putative 0.0048 0.0066 0.0063
Echinococcus granulosus thioredoxin glutathione reductase 0.004 0.0046 0.0064
Brugia malayi hypothetical protein 0.0059 0.0095 0.009
Echinococcus multilocularis rhodopsin orphan GPCR 0.047 0.1176 0.1634
Brugia malayi follicle stimulating hormone receptor 0.1144 0.2949 0.2945
Schistosoma mansoni pyruvate kinase 0.0035 0.0032 0.0024
Brugia malayi Twik (KCNK-like) family of potassium channels, alpha subunit 21 0.0075 0.0137 0.0131
Trichomonas vaginalis alpha-glucosidase, putative 0.0035 0.0033 0.0026
Trypanosoma brucei calcium/potassium channel (CAKC), putative 0.0075 0.0137 0.0112
Brugia malayi jmjC domain containing protein 0.0222 0.0525 0.0519
Echinococcus granulosus uncharacterized sodium dependent transporter 0.0031 0.0021 0.003
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0047 0.0065 0.0059
Brugia malayi hypothetical protein 0.0075 0.0137 0.0131
Echinococcus granulosus voltage dependent calcium channel type d subunit|voltage dependent calcium channel alpha 1 0.0085 0.0165 0.0229
Trichomonas vaginalis acetylornithine aminotransferase, putative 0.0147 0.0328 0.1049
Trichomonas vaginalis flap endonuclease-1, putative 0.0057 0.009 0.0224
Toxoplasma gondii isocitrate dehydrogenase 0.0033 0.0028 0.0342
Brugia malayi Melatonin receptor type 1A 0.047 0.1176 0.1171
Schistosoma mansoni jumonji/arid domain-containing protein 0.0166 0.0378 0.0506
Loa Loa (eye worm) hypothetical protein 0.0241 0.0574 0.0574
Echinococcus granulosus glucose 6 phosphate 1 dehydrogenase 0.0098 0.0198 0.0275
Trichomonas vaginalis alpha-glucosidase, putative 0.0035 0.0033 0.0026
Loa Loa (eye worm) pyruvate kinase 0.0035 0.0032 0.0032
Mycobacterium tuberculosis Probable cytochrome P450 136 Cyp136 0.0063 0.0107 0.0209
Echinococcus granulosus somatostatin receptor 0.047 0.1176 0.1634
Onchocerca volvulus 0.047 0.1176 0.4644
Loa Loa (eye worm) hypothetical protein 0.0103 0.0211 0.0211
Schistosoma mansoni inositol monophosphatase 0.0109 0.0227 0.0296
Brugia malayi hypothetical protein 0.047 0.1176 0.1171
Plasmodium falciparum importin beta, putative 0.0059 0.0095 0.1103
Schistosoma mansoni TGF-beta signal transducer Smad2 0.005 0.0073 0.008
Loa Loa (eye worm) nicotinic acetylcholine receptor non-alpha subunit 0.0103 0.0211 0.0211
Mycobacterium ulcerans glucose-6-phosphate 1-dehydrogenase 0.0098 0.0198 0.066
Schistosoma mansoni cpg binding protein 0.0062 0.0103 0.0123
Mycobacterium tuberculosis Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB 0.0091 0.0178 0.0357
Mycobacterium tuberculosis Probable lipase LipE 0.0074 0.0134 0.0266
Schistosoma mansoni nuclear hormone receptor 0.0031 0.0022 0.001
Loa Loa (eye worm) 5-hydroxytryptamine 2C receptor 0.047 0.1176 0.1176
Loa Loa (eye worm) hypothetical protein 0.047 0.1176 0.1176
Echinococcus multilocularis Smad4 0.005 0.0073 0.0101
Trichomonas vaginalis importin beta-1, putative 0.0048 0.0066 0.014
Mycobacterium tuberculosis Adenosylmethionine-8-amino-7-oxononanoate aminotransferase BioA 0.0147 0.0328 0.0667
Trypanosoma brucei inositol-1(or 4)-monophosphatase 1, putative 0.0109 0.0227 0.0203
Schistosoma mansoni neuropeptide receptor 0.047 0.1176 0.1617
Schistosoma mansoni cytochrome P450 0.0063 0.0107 0.0128
Schistosoma mansoni high voltage-activated calcium channel Cav2A 0.0085 0.0165 0.0209
Echinococcus granulosus transient receptor potential ion channel A 0.0092 0.0182 0.0253
Mycobacterium tuberculosis Inositol-1-monophosphatase SuhB 0.0098 0.0197 0.0396
Onchocerca volvulus 0.0059 0.0095 0.0353
Schistosoma mansoni hypothetical protein 0.0627 0.1589 0.2192
Echinococcus multilocularis transient receptor potential ion channel A 0.0092 0.0182 0.0253
Schistosoma mansoni rhodopsin-like orphan GPCR 0.047 0.1176 0.1617
Loa Loa (eye worm) hypothetical protein 0.0047 0.0065 0.0065
Mycobacterium leprae PROBABLE ATP-DEPENDENT CLP PROTEASE PROTEOLYTIC SUBUNIT 2 CLPP2 (ENDOPEPTIDASE CLP 2) 0.0082 0.0156 0.0894
Schistosoma mansoni myelin transcription factor 1 myt1 0.0062 0.0102 0.0121
Brugia malayi Nuclear hormone receptor family member nhr-14 0.0031 0.0022 0.0016
Schistosoma mansoni survival motor neuron protein 0.0047 0.0063 0.0067
Loa Loa (eye worm) MH2 domain-containing protein 0.005 0.0073 0.0073
Trypanosoma cruzi hypothetical protein, conserved 0.0074 0.0134 0.0111
Loa Loa (eye worm) hypothetical protein 0.0103 0.0211 0.0211
Schistosoma mansoni adenoreceptor 0.047 0.1176 0.1617
Echinococcus multilocularis GPCR, family 2 0.0049 0.0069 0.0095
Leishmania major flap endonuclease-1 (FEN-1), putative 0.0057 0.009 0.0087
Echinococcus multilocularis rhodopsin orphan GPCR 0.047 0.1176 0.1634
Loa Loa (eye worm) glutaminase 0.1131 0.2914 0.2914
Loa Loa (eye worm) hypothetical protein 0.0066 0.0115 0.0115
Echinococcus multilocularis isocitrate dehydrogenase 2 (NADP+) 0.0033 0.0028 0.0039
Loa Loa (eye worm) hypothetical protein 0.0103 0.0211 0.0211
Echinococcus multilocularis tachykinin peptides receptor 99D 0.047 0.1176 0.1634
Leishmania major ion transport protein-like protein 0.0075 0.0137 0.0134
Trichomonas vaginalis pyruvate kinase, putative 0.0035 0.0032 0.0026
Echinococcus granulosus tyrosyl DNA phosphodiesterase 1 0.013 0.0283 0.0393
Loa Loa (eye worm) hypothetical protein 0.012 0.0256 0.0256
Schistosoma mansoni hypothetical protein 0.0105 0.0217 0.0282
Mycobacterium ulcerans cytochrome P450 189A7 Cyp189A7 0.0063 0.0107 0.0347
Brugia malayi excitatory GABA receptor EXP-1A 0.0103 0.0211 0.0205
Brugia malayi Serotonin receptor 0.047 0.1176 0.1171
Mycobacterium tuberculosis Conserved protein 0.0074 0.0134 0.0266
Trypanosoma cruzi peptidyl-prolyl cis-trans isomerase 0.0032 0.0025 0.0002
Brugia malayi hypothetical protein 0.047 0.1176 0.1171
Entamoeba histolytica glycosyl hydrolase, family 31 protein 0.0035 0.0033 0.0104
Trypanosoma brucei recA bacterial DNA recombination protein, putative 0.0035 0.0032 0.0007
Brugia malayi Serotonin receptor 0.047 0.1176 0.1171
Mycobacterium tuberculosis Probable ATP-dependent CLP protease proteolytic subunit 2 ClpP2 (endopeptidase CLP 2) 0.0054 0.0082 0.0157
Loa Loa (eye worm) hypothetical protein 0.047 0.1176 0.1176
Echinococcus granulosus voltage dependent calcium channel 0.0085 0.0165 0.0229
Trichomonas vaginalis penicillin-binding protein, putative 0.0074 0.0134 0.0379
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0141 0.0312 0.0306
Entamoeba histolytica hypothetical protein 0.0298 0.0724 0.2675
Schistosoma mansoni smad 0.005 0.0073 0.008
Trypanosoma cruzi DNA repair protein, putative 0.0035 0.0032 0.0009
Schistosoma mansoni acetylcholine receptor subunit beta 0.0047 0.0065 0.007
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0053 0.0079 0.0056
Echinococcus granulosus Cys loop ligand gated ion channel subunit 0.0047 0.0065 0.0091
Trypanosoma brucei cytochrome P450, putative 0.0117 0.0249 0.0225
Leishmania major potassium channel subunit-like protein 0.0075 0.0137 0.0134
Echinococcus multilocularis lipoxygenase domain containing protein 0.0059 0.0095 0.0133
Echinococcus granulosus 7tm_1 domain containing protein 0.047 0.1176 0.1634
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0125 0.0269 0.0354
Entamoeba histolytica calcium-gated potassium channel protein, putative 0.0075 0.0137 0.0493
Toxoplasma gondii aminopeptidase n, putative 0.0304 0.074 1
Trypanosoma brucei protein kinase, putative 0.0053 0.0079 0.0054
Mycobacterium tuberculosis Probable short-chain type dehydrogenase/reductase 0.006 0.0099 0.0192
Schistosoma mansoni biogenic amine (dopamine) receptor 0.047 0.1176 0.1617
Trypanosoma cruzi cytochrome P450, putative 0.0117 0.0249 0.0227
Loa Loa (eye worm) steroid hormone receptor 0.0031 0.0022 0.0022
Brugia malayi hypothetical protein 0.0082 0.0155 0.015
Echinococcus granulosus caspase 2 0.0102 0.0208 0.0289
Echinococcus granulosus glycine receptor subunit alpha 1 0.0103 0.0211 0.0293
Schistosoma mansoni sodium/chloride dependent neurotransmitter transporter 0.0031 0.0021 0.0009
Loa Loa (eye worm) hypothetical protein 0.047 0.1176 0.1176
Schistosoma mansoni transient receptor potential channel 0.0071 0.0127 0.0156
Brugia malayi Neurotransmitter-gated ion-channel transmembrane region family protein 0.0055 0.0086 0.008
Entamoeba histolytica hypothetical protein 0.0048 0.0066 0.0227
Echinococcus granulosus acetylcholinesterase 0.0069 0.0121 0.0168
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0109 0.0227 0.0701
Schistosoma mansoni rhodopsin-like orphan GPCR 0.047 0.1176 0.1617
Loa Loa (eye worm) hypothetical protein 0.047 0.1176 0.1176
Trichomonas vaginalis glucosylceramidase, putative 0.0175 0.0401 0.1301
Loa Loa (eye worm) hypothetical protein 0.0103 0.0211 0.0211
Mycobacterium leprae Probable lipase LipE 0.0074 0.0134 0.0765
Schistosoma mansoni pyruvate kinase 0.0035 0.0032 0.0024
Loa Loa (eye worm) hypothetical protein 0.047 0.1176 0.1176
Trypanosoma cruzi PAB1-binding protein , putative 0.0103 0.021 0.0187
Echinococcus granulosus glycine receptor subunit beta 0.0103 0.0211 0.0293
Loa Loa (eye worm) hypothetical protein 0.0075 0.0137 0.0137
Mycobacterium ulcerans extragenic suppressor protein SuhB 0.0109 0.0227 0.0762
Schistosoma mansoni caspase-7 (C14 family) 0.0102 0.0208 0.0269
Mycobacterium tuberculosis Probable glucose-6-phosphate 1-dehydrogenase Zwf2 (G6PD) 0.0034 0.003 0.0049
Echinococcus multilocularis g protein coupled receptor 0.047 0.1176 0.1634
Onchocerca volvulus 0.047 0.1176 0.4644
Echinococcus multilocularis flap endonuclease 1 0.0057 0.009 0.0125
Echinococcus multilocularis p2X purinoceptor 4 0.0067 0.0116 0.0161
Entamoeba histolytica acyl-CoA synthetase, putative 0.0025 0.0006 0.0005
Echinococcus granulosus suppression of tumorigenicity 18 protein 0.0062 0.0102 0.0142
Echinococcus granulosus nicotinic acetylcholine receptor beta 1 subunit 0.0103 0.0211 0.0293
Onchocerca volvulus Polycomb protein Sfmbt homolog 0.0054 0.0083 0.0305
Trypanosoma cruzi isocitrate dehydrogenase, putative 0.0033 0.0028 0.0005
Trypanosoma cruzi cytochrome P450, putative 0.0117 0.0249 0.0227
Schistosoma mansoni nAChR subunit (ShAR1-beta-like) 0.0241 0.0574 0.0778
Schistosoma mansoni 3-hydroxyacyl-CoA dehydrogenase 0.006 0.0099 0.0116
Trichomonas vaginalis CMGC family protein kinase 0.0053 0.0079 0.0188
Echinococcus multilocularis acetylcholine receptor subunit beta 1 0.0103 0.0211 0.0293
Loa Loa (eye worm) hypothetical protein 0.047 0.1176 0.1176
Echinococcus granulosus importin subunit beta 1 0.0059 0.0095 0.0132
Schistosoma mansoni hypothetical protein 0.0075 0.0137 0.017
Loa Loa (eye worm) hypothetical protein 0.0075 0.0137 0.0137
Brugia malayi beta-lactamase family protein 0.0074 0.0134 0.0129
Echinococcus multilocularis neuropeptide receptor 0.047 0.1176 0.1634
Brugia malayi beta-lactamase family protein 0.0074 0.0134 0.0129
Entamoeba histolytica exodeoxyribonuclease III, putative 0.0056 0.0088 0.0312
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.047 0.1176 0.1634
Loa Loa (eye worm) thioredoxin reductase 0.004 0.0045 0.0045
Loa Loa (eye worm) hypothetical protein 0.0103 0.0211 0.0211
Echinococcus multilocularis glucose 6 phosphate 1 dehydrogenase 0.0098 0.0198 0.0275
Treponema pallidum exodeoxyribonuclease (exoA) 0.0056 0.0088 0.1006
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.0031 0.0022 0.0031
Echinococcus multilocularis geminin 0.1912 0.4969 0.6907
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0146 0.0324 0.1034
Echinococcus granulosus rhodopsin orphan GPCR 0.047 0.1176 0.1634
Loa Loa (eye worm) jmjC domain-containing protein 0.0043 0.0055 0.0055
Loa Loa (eye worm) hypothetical protein 0.0075 0.0137 0.0137
Trichomonas vaginalis conserved hypothetical protein 0.0033 0.0027 0.0007
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.0031 0.0022 0.0022
Plasmodium falciparum glucose-6-phosphate dehydrogenase-6-phosphogluconolactonase 0.0107 0.0221 0.2838
Leishmania major 4-coumarate:coa ligase-like protein 0.0025 0.0006 0.0003
Onchocerca volvulus Pyruvate kinase homolog 0.0035 0.0032 0.0106
Loa Loa (eye worm) hypothetical protein 0.0069 0.0121 0.0121
Echinococcus granulosus NADP dependent isocitrate dehydrogenase 0.0033 0.0028 0.0039
Schistosoma mansoni loxhd1 0.0059 0.0095 0.0112
Chlamydia trachomatis ATP-dependent Clp protease proteolytic subunit 0.0082 0.0156 0.6217
Echinococcus multilocularis muscleblind protein 0.0168 0.0381 0.053
Brugia malayi Twik (KCNK-like) family of potassium channels, alpha subunit 12 0.0075 0.0137 0.0131
Trypanosoma brucei hypothetical protein, conserved 0.0074 0.0134 0.011
Mycobacterium tuberculosis Probable lipase LipD 0.0074 0.0134 0.0266
Trichomonas vaginalis bromodomain-containing protein, putative 0.0127 0.0275 0.0865
Entamoeba histolytica tyrosyl-DNA phosphodiesterase, putative 0.013 0.0283 0.1034
Schistosoma mansoni hypothetical protein 0.0059 0.0095 0.0112
Echinococcus granulosus thyrotropin releasing hormone receptor 0.047 0.1176 0.1634
Echinococcus granulosus single minded 2 0.0045 0.0058 0.0081
Echinococcus granulosus expressed protein 0.0033 0.0027 0.0038
Brugia malayi glutamate-gated chloride channel alpha3A subunit, putative 0.0047 0.0065 0.0059
Loa Loa (eye worm) jmjC domain-containing protein 0.0043 0.0055 0.0055
Echinococcus granulosus G protein coupled receptor 139 0.047 0.1176 0.1634
Schistosoma mansoni nAChR subunit 0.0103 0.0211 0.0273
Mycobacterium tuberculosis Cytochrome P450 51 Cyp51 (CYPL1) (P450-L1A1) (sterol 14-alpha demethylase) (lanosterol 14-alpha demethylase) (P450-14DM) 0.0063 0.0107 0.0209
Onchocerca volvulus 0.0075 0.0137 0.0522
Echinococcus granulosus geminin 0.1912 0.4969 0.6907
Echinococcus granulosus Transcription factor JmjC domain containing protein 0.0222 0.0525 0.0729
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.0031 0.0022 0.0031
Schistosoma mansoni jumonji/arid domain-containing protein 0.0166 0.0378 0.0506
Echinococcus granulosus sodium:chloride dependent neurotransmitter 0.0031 0.0021 0.003
Chlamydia trachomatis pyruvate kinase 0.0035 0.0032 0.0506
Brugia malayi Twik (KCNK-like) family of potassium channels, alpha subunit 24 0.0075 0.0137 0.0131
Mycobacterium tuberculosis Probable oxidoreductase 0.0101 0.0205 0.0412
Schistosoma mansoni polycystin 1-related 0.0059 0.0095 0.0112
Echinococcus multilocularis serotonin transporter 0.0182 0.0418 0.0581
Mycobacterium tuberculosis Probable reductase 0.0091 0.0178 0.0357
Echinococcus multilocularis Polycystic kidney disease protein 0.0059 0.0095 0.0133
Loa Loa (eye worm) hypothetical protein 0.0102 0.0208 0.0208
Loa Loa (eye worm) hypothetical protein 0.0025 0.0006 0.0006
Echinococcus multilocularis voltage dependent L type calcium channel subunit 0.0085 0.0165 0.0229
Loa Loa (eye worm) hypothetical protein 0.0031 0.0022 0.0022
Entamoeba histolytica Acid sphingomyelinase-like phosphodiesterase, putative 0.0169 0.0384 0.1412
Plasmodium falciparum thioredoxin reductase 0.004 0.0045 0.0414
Plasmodium falciparum flap endonuclease 1 0.0057 0.009 0.1036
Loa Loa (eye worm) hypothetical protein 0.0047 0.0065 0.0065
Loa Loa (eye worm) tyrosyl-DNA phosphodiesterase 0.013 0.0283 0.0283
Onchocerca volvulus 0.047 0.1176 0.4644
Brugia malayi Nuclear hormone receptor family member nhr-3 0.0031 0.0022 0.0016
Loa Loa (eye worm) hypothetical protein 0.047 0.1176 0.1176
Onchocerca volvulus 0.047 0.1176 0.4644
Loa Loa (eye worm) hypothetical protein 0.0075 0.0137 0.0137
Mycobacterium tuberculosis Probable conserved lipoprotein 0.0074 0.0134 0.0266
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0048 0.0066 0.014
Plasmodium vivax multidomain scavenger receptor, putative 0.0059 0.0095 0.1112
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0103 0.0211 0.0205
Onchocerca volvulus 0.0059 0.0095 0.0356
Brugia malayi MH2 domain containing protein 0.0738 0.1881 0.1876
Echinococcus multilocularis mitogen activated protein kinase 3 0.0053 0.0079 0.011
Brugia malayi jmjC domain containing protein 0.0043 0.0055 0.0049
Brugia malayi glucose-6-phosphate dehydrogenase 0.0098 0.0198 0.0192
Schistosoma mansoni NADP-specific isocitrate dehydrogenase 0.0033 0.0028 0.0018
Brugia malayi Pyruvate kinase, M2 isozyme 0.0035 0.0032 0.0027
Onchocerca volvulus 0.0055 0.0086 0.0319
Mycobacterium leprae PROBABLE NADH DEHYDROGENASE NDH 0.0091 0.0178 0.1027
Loa Loa (eye worm) hypothetical protein 0.0047 0.0065 0.0065
Echinococcus multilocularis g-protein coupled receptor 0.047 0.1176 0.1634
Echinococcus multilocularis glycine receptor subunit beta 0.0103 0.0211 0.0293
Trichomonas vaginalis glucosylceramidase, putative 0.0175 0.0401 0.1301
Trypanosoma brucei pyruvate kinase 1 0.0035 0.0032 0.0007
Loa Loa (eye worm) MH2 domain-containing protein 0.0738 0.1881 0.1881
Brugia malayi Steroid receptor seven-up type 2 0.0031 0.0022 0.0016
Schistosoma mansoni peptide (allatostatin/somatostatin)-like receptor 0.047 0.1176 0.1617
Mycobacterium ulcerans glutaminase 0.1131 0.2914 1
Brugia malayi Glycosyl hydrolases family 31 protein 0.0158 0.0356 0.035
Schistosoma mansoni sodium/chloride dependent transporter 0.0031 0.0023 0.0011
Trichomonas vaginalis alpha-galactosidase/alpha-N-acetylgalactosaminidase, putative 0.0066 0.0115 0.031
Toxoplasma gondii isocitrate dehydrogenase 0.0033 0.0028 0.0342
Echinococcus granulosus tm gpcr rhodopsin 0.047 0.1176 0.1634
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.0031 0.0022 0.0065
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0141 0.0312 0.0414
Loa Loa (eye worm) hypothetical protein 0.047 0.1176 0.1176
Schistosoma mansoni family S9 non-peptidase homologue (S09 family) 0.0069 0.0121 0.0147
Schistosoma mansoni hypothetical protein 0.0046 0.0061 0.0064
Echinococcus multilocularis fmrfamide receptor 0.047 0.1176 0.1634
Brugia malayi Cation transporter family protein 0.0241 0.0574 0.0568
Schistosoma mansoni intermediate filament proteins 0.0143 0.0316 0.042
Loa Loa (eye worm) hypothetical protein 0.0171 0.0391 0.0391
Loa Loa (eye worm) hypothetical protein 0.0031 0.0022 0.0022
Schistosoma mansoni phd/f-box containing protein 0.0043 0.0055 0.0055
Trypanosoma cruzi calcium/potassium channel (CAKC), putative 0.0075 0.0137 0.0114
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0119 0.0254 0.0353
Brugia malayi Neurotransmitter-gated ion-channel transmembrane region family protein 0.0103 0.0211 0.0205
Loa Loa (eye worm) hypothetical protein 0.0025 0.0006 0.0006
Plasmodium vivax AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0056 0.0088 0.1015
Onchocerca volvulus 0.047 0.1176 0.4644
Schistosoma mansoni hypothetical protein 0.0043 0.0055 0.0055
Loa Loa (eye worm) hypothetical protein 0.0059 0.0095 0.0095
Echinococcus multilocularis acetylcholinesterase 0.0069 0.0121 0.0168
Echinococcus multilocularis thioredoxin glutathione reductase 0.004 0.0046 0.0064
Schistosoma mansoni P2X receptor subunit 0.0067 0.0116 0.0141
Loa Loa (eye worm) hypothetical protein 0.047 0.1176 0.1176
Echinococcus multilocularis fmrfamide receptor 0.047 0.1176 0.1634
Echinococcus multilocularis sodium:chloride dependent neurotransmitter 0.0031 0.0021 0.003
Onchocerca volvulus Pyruvate kinase homolog 0.0035 0.0032 0.0106
Schistosoma mansoni P2X receptor subunit 0.0067 0.0116 0.0141
Loa Loa (eye worm) Pin1-type peptidyl-prolyl cis-trans isomerase 0.0033 0.0027 0.0027
Toxoplasma gondii flap structure-specific endonuclease 1, putative 0.0057 0.009 0.1183
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0031 0.0022 0.0031
Loa Loa (eye worm) follicle stimulating hormone receptor 0.1144 0.2949 0.2949
Mycobacterium ulcerans hypothetical protein 0.0074 0.0134 0.0442
Trypanosoma cruzi tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.013 0.0283 0.026
Loa Loa (eye worm) hypothetical protein 0.0047 0.0065 0.0065
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0031 0.0022 0.0016
Leishmania major hypothetical protein, conserved 0.0075 0.0137 0.0134
Echinococcus granulosus serotonin receptor 0.047 0.1176 0.1634
Toxoplasma gondii ATP-dependent Clp endopeptidase, proteolytic subunit ClpP domain-containing protein 0.0082 0.0156 0.2082
Echinococcus granulosus rhodopsin orphan GPCR 0.047 0.1176 0.1634
Echinococcus multilocularis lipoxygenase domain containing protein 0.0059 0.0095 0.0133
Loa Loa (eye worm) hypothetical protein 0.047 0.1176 0.1176
Echinococcus granulosus mitogen activated protein kinase 3 0.0053 0.0079 0.011
Toxoplasma gondii LsmAD domain-containing protein 0.0103 0.021 0.2813
Echinococcus multilocularis arachidonate 5 lipoxygenase 0.0287 0.0694 0.0965
Schistosoma mansoni nAChR subunit 0.0103 0.0211 0.0273
Schistosoma mansoni neuropeptide F-like receptor 0.047 0.1176 0.1617
Brugia malayi Muscleblind-like protein 0.0168 0.0381 0.0376
Trichomonas vaginalis esterase, putative 0.0074 0.0134 0.0379
Echinococcus multilocularis sodium and chloride dependent glycine 0.0031 0.0021 0.003
Loa Loa (eye worm) hypothetical protein 0.0031 0.0021 0.0021
Mycobacterium ulcerans transmembrane cation transporter 0.0075 0.0137 0.0452
Loa Loa (eye worm) jmjC domain-containing protein 0.0059 0.0096 0.0096
Schistosoma mansoni peptide (allatostatin)-like receptor 0.047 0.1176 0.1617
Onchocerca volvulus 0.0082 0.0155 0.0593
Echinococcus granulosus arachidonate 5 lipoxygenase 0.0287 0.0694 0.0965
Loa Loa (eye worm) excitatory GABA receptor EXP-1A 0.0103 0.0211 0.0211
Leishmania major ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative 0.0052 0.0076 0.0073
Brugia malayi intermediate filament protein 0.0143 0.0316 0.0311
Echinococcus granulosus rhodopsin orphan GPCR 0.047 0.1176 0.1634
Echinococcus granulosus transcription factor Dp 1 0.0075 0.0139 0.0193
Schistosoma mansoni voltage-gated potassium channel 0.0089 0.0175 0.0223
Echinococcus granulosus acetylcholinesterase 0.0069 0.0121 0.0168
Trichomonas vaginalis glucosylceramidase, putative 0.0175 0.0401 0.1301
Loa Loa (eye worm) hypothetical protein 0.0103 0.0211 0.0211
Toxoplasma gondii hypothetical protein 0.0031 0.0021 0.0256
Onchocerca volvulus 0.0182 0.0418 0.1636
Trichomonas vaginalis glucosylceramidase, putative 0.0175 0.0401 0.1301
Schistosoma mansoni ubiquitin-specific peptidase 8 (C19 family) 0.0052 0.0076 0.0085
Loa Loa (eye worm) nicotinic acetylcholine receptor alpha subunit 0.024 0.0572 0.0572
Loa Loa (eye worm) hypothetical protein 0.0083 0.0159 0.0159
Toxoplasma gondii PHD-finger domain-containing protein 0.0029 0.0016 0.0178
Echinococcus multilocularis expressed protein 0.0033 0.0027 0.0038
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0074 0.0134 0.0134
Trypanosoma cruzi hypothetical protein, conserved 0.0033 0.0028 0.0005
Mycobacterium tuberculosis Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) 0.0056 0.0088 0.0171
Schistosoma mansoni rhodopsin-like orphan GPCR 0.047 0.1176 0.1617
Toxoplasma gondii Sodium:neurotransmitter symporter family protein 0.0031 0.0021 0.0256
Toxoplasma gondii Sodium:neurotransmitter symporter family protein 0.0031 0.0021 0.0256
Schistosoma mansoni sodium-dependent neurotransmitter transporter 0.0031 0.0021 0.0009
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase domain containing protein 0.0052 0.0076 0.0266
Trypanosoma cruzi hypothetical protein, conserved 0.0074 0.0134 0.0111
Loa Loa (eye worm) intermediate filament protein 0.0143 0.0316 0.0316
Brugia malayi MH1 domain containing protein 0.005 0.0073 0.0067
Echinococcus granulosus carboxylesterase 5A 0.0069 0.0121 0.0168
Toxoplasma gondii Sodium:neurotransmitter symporter family protein 0.0031 0.0021 0.0256
Schistosoma mansoni calcium-activated potassium channel 0.0075 0.0137 0.017
Echinococcus multilocularis G protein coupled 5 hydroxytryptamine receptor 0.047 0.1176 0.1634
Brugia malayi MH1 domain containing protein 0.005 0.0073 0.0067
Treponema pallidum ATP-dependent Clp protease proteolytic subunit 0.0082 0.0156 0.1932
Echinococcus granulosus muscleblind protein 0.0168 0.0381 0.053
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0146 0.0324 0.1034
Schistosoma mansoni opsin-like receptor 0.047 0.1176 0.1617
Brugia malayi O-Glycosyl hydrolase family 30 protein 0.0267 0.0642 0.0637
Schistosoma mansoni steroid hormone receptor ad4bp 0.0031 0.0022 0.001
Wolbachia endosymbiont of Brugia malayi ATP-dependent Clp protease proteolytic subunit 0.0082 0.0156 0.4526
Loa Loa (eye worm) MBCTL1 0.0062 0.0102 0.0102
Brugia malayi Glycosyl hydrolases family 31 protein 0.0035 0.0033 0.0027
Schistosoma mansoni twik family of potassium channels-related 0.0075 0.0137 0.017
Echinococcus granulosus lipoxygenase domain containing protein 0.0059 0.0095 0.0133
Onchocerca volvulus 0.047 0.1176 0.4644
Echinococcus granulosus voltage dependent L type calcium channel subunit|voltage dependent calcium channel 0.0085 0.0165 0.0229
Mycobacterium ulcerans fructose-bisphosphate aldolase 0.015 0.0334 0.113
Echinococcus granulosus Peptidase C19 ubiquitin carboxyl terminal hydrolase 2 0.0052 0.0076 0.0106
Brugia malayi Cytochrome P450 family protein 0.0117 0.0249 0.0244
Trichomonas vaginalis rotamase, putative 0.0033 0.0027 0.0007
Trichomonas vaginalis glucosylceramidase, putative 0.0267 0.0642 0.2136
Echinococcus multilocularis g protein coupled receptor 0.047 0.1176 0.1634
Loa Loa (eye worm) doublecortin family protein 0.0059 0.0095 0.0095
Brugia malayi hypothetical protein 0.0343 0.0841 0.0836
Giardia lamblia DNA repair protein RAD52 0.1048 0.2695 1
Echinococcus granulosus Two pore potassium channel protein sup 9 0.0075 0.0137 0.0191
Mycobacterium ulcerans cytochrome P450 123A3 Cyp123A3 0.0063 0.0107 0.0347
Echinococcus granulosus twik family of potassium channels 0.0075 0.0137 0.0191
Loa Loa (eye worm) acetyltransferase 0.0433 0.1078 0.1078
Trichomonas vaginalis glucosamine-6-phosphate isomerase, putative 0.0107 0.0221 0.0677
Loa Loa (eye worm) calcium channel 0.0085 0.0165 0.0165
Plasmodium falciparum ataxin-2 like protein, putative 0.0103 0.021 0.2692
Loa Loa (eye worm) hypothetical protein 0.0055 0.0086 0.0086
Loa Loa (eye worm) hypothetical protein 0.0074 0.0134 0.0134
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.047 0.1176 0.1634
Schistosoma mansoni cpg binding protein 0.0062 0.0103 0.0123
Loa Loa (eye worm) hypothetical protein 0.0055 0.0086 0.0086
Schistosoma mansoni hypothetical protein 0.1912 0.4969 0.6901
Mycobacterium tuberculosis Probable cytochrome P450 monooxygenase 142 Cyp142 0.0063 0.0107 0.0209
Schistosoma mansoni nAChR subunit 0.0103 0.0211 0.0273
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.0031 0.0022 0.0022
Echinococcus granulosus peregrin 0.0039 0.0044 0.006
Echinococcus multilocularis twik family of potassium channels 0.0075 0.0137 0.0191
Loa Loa (eye worm) acetylcholine receptor alpha subunit 0.0103 0.0211 0.0211
Loa Loa (eye worm) hypothetical protein 0.047 0.1176 0.1176
Schistosoma mansoni alpha-galactosidase/alpha-n-acetylgalactosaminidase 0.0066 0.0115 0.0139
Schistosoma mansoni biogenic amine (octopamine/dopamine) receptor 0.047 0.1176 0.1617
Brugia malayi Sodium:neurotransmitter symporter family protein 1, putative 0.0031 0.0021 0.0016
Schistosoma mansoni acetylcholine receptor-related 0.0047 0.0065 0.007
Loa Loa (eye worm) hypothetical protein 0.047 0.1176 0.1176
Loa Loa (eye worm) hypothetical protein 0.0075 0.0137 0.0137
Echinococcus granulosus glycine receptor subunit beta 0.0103 0.0211 0.0293
Schistosoma mansoni serine/threonine protein kinase 0.0053 0.0079 0.0089
Loa Loa (eye worm) hypothetical protein 0.0031 0.0021 0.0021
Leishmania major pyruvate kinase 0.0035 0.0032 0.003
Echinococcus multilocularis 7TM GPCR, rhodopsin 0.047 0.1176 0.1634
Trypanosoma cruzi hypothetical protein, conserved 0.0033 0.0028 0.0005
Mycobacterium tuberculosis Probable cytochrome P450 130 Cyp130 0.0063 0.0107 0.0209
Trypanosoma cruzi ion transport protein, putative 0.0075 0.0137 0.0114
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0031 0.0022 0.0016
Onchocerca volvulus 0.0075 0.0137 0.0522
Mycobacterium tuberculosis Probable cytochrome P450 139 Cyp139 0.0063 0.0107 0.0209
Loa Loa (eye worm) hypothetical protein 0.0055 0.0086 0.0086
Echinococcus multilocularis glycine receptor subunit alpha 1 0.0103 0.0211 0.0293
Echinococcus multilocularis transcription factor Dp 1 0.0075 0.0139 0.0193
Entamoeba histolytica hypothetical protein 0.0043 0.0055 0.0186
Brugia malayi gonadotropin-releasing hormone receptor 2 0.047 0.1176 0.1171
Echinococcus multilocularis histone acetyltransferase MYST2 0.0062 0.0102 0.0142
Echinococcus multilocularis caspase 2 0.0102 0.0208 0.0289
Loa Loa (eye worm) unidentified vitellogenin-linked transcript protein 6 0.047 0.1176 0.1176
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.047 0.1176 0.1634
Loa Loa (eye worm) Sodium:neurotransmitter symporter family protein 0.0031 0.0021 0.0021
Brugia malayi mbt repeat family protein 0.0054 0.0083 0.0077
Echinococcus multilocularis G protein coupled receptor 139 0.047 0.1176 0.1634
Echinococcus granulosus p2X purinoceptor 4 0.0067 0.0116 0.0161
Echinococcus multilocularis voltage dependent calcium channel type d subunit 0.0085 0.0165 0.0229
Echinococcus granulosus glycine receptor subunit alpha 1 0.0103 0.0211 0.0293
Loa Loa (eye worm) hypothetical protein 0.0075 0.0137 0.0137
Loa Loa (eye worm) jmjC domain-containing protein 0.0043 0.0055 0.0055
Echinococcus granulosus biogenic amine 5HT receptor 0.0861 0.2205 0.3065
Echinococcus multilocularis lamin 0.0143 0.0316 0.044
Brugia malayi GTP-binding nuclear protein RAN/TC4 0.0043 0.0054 0.0048
Brugia malayi Melibiase family protein 0.0066 0.0115 0.0109
Echinococcus multilocularis voltage gated potassium channel 0.0028 0.0015 0.0021
Echinococcus granulosus neuropeptide s receptor 0.047 0.1176 0.1634
Loa Loa (eye worm) hypothetical protein 0.0066 0.0115 0.0115
Echinococcus multilocularis pyruvate kinase 0.0035 0.0032 0.0045
Loa Loa (eye worm) glutamate-gated chloride channel alpha3A subunit 0.0047 0.0065 0.0065
Onchocerca volvulus 0.0075 0.0137 0.0522
Trypanosoma cruzi membrane transporter protein, putative 0.0033 0.0028 0.0005
Echinococcus granulosus jumonji domain containing 1A 0.0043 0.0055 0.0076

Activities

Activity type Activity value Assay description Source Reference
Potency (functional) 18.3564 uM PUBCHEM_BIOASSAY: Nrf2 qHTS screen for inhibitors. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID493153, AID493163, AID504648] ChEMBL. No reference
Potency (functional) 23.9341 uM PUBCHEM_BIOASSAY: qHTS profiling assay for firefly luciferase inhibitor/activator using purified enzyme and Km concentrations of substrates (counterscreen for miR-21 project). (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID2288, AID2289, AID2598, AID411] ChEMBL. No reference
Potency (functional) = 28.1838 um PUBCHEM_BIOASSAY: qHTS Inhibitors of AmpC Beta-Lactamase (assay with detergent). (Class of assay: confirmatory) [Related pubchem assays: 1002 (Confirmation Concentration-Response Assay for Inhibitors of AmpC Beta-Lactamase (assay with detergent)), 585 (Promiscuous and Specific Inhibitors of AmpC Beta-Lactamase (assay without detergent) - a screen old NIH MLSMR collection), 584 (Promiscuous and Specific Inhibitors of AmpC Beta-Lactamase (assay with detergent) - a screen of the old NIH MLSMR collection), 1003 (Confirmation Cuvette-Based Assay for Inhibitors of AmpC Beta-Lactamase (assay with detergent))] ChEMBL. No reference
Potency (functional) = 89.1251 um PUBCHEM_BIOASSAY: qHTS Assay for Inhibitors of DNA Polymerase Beta. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) 100 uM PUBCHEM_BIOASSAY: HTS for Inhibitors of HP1-beta Chromodomain Interactions with Methylated Histone Tails. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID488962] ChEMBL. No reference

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

Bibliographic References

No literature references available for this target.

If you have references for this compound, please enter them in a user comment (below) or Contact us.