Detailed information for compound 1394524

Basic information

Technical information
  • TDR Targets ID: 1394524
  • Name: N,N-diethyl-1-octylpyridin-1-ium-3-carboxamid e bromide
  • MW: 371.356 | Formula: C18H31BrN2O
  • H donors: 0 H acceptors: 1 LogP: 5.5 Rotable bonds: 11
    Rule of 5 violations (Lipinski): 1
  • SMILES: CCCCCCCC[n+]1cccc(c1)C(=O)N(CC)CC.[Br-]
  • InChi: 1S/C18H31N2O.BrH/c1-4-7-8-9-10-11-14-19-15-12-13-17(16-19)18(21)20(5-2)6-3;/h12-13,15-16H,4-11,14H2,1-3H3;1H/q+1;/p-1
  • InChiKey: SVWZSLCYZNZNAC-UHFFFAOYSA-M  


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Synonyms

  • N,N-diethyl-1-octyl-pyridin-1-ium-3-carboxamide bromide
  • N,N-diethyl-1-octyl-3-pyridin-1-iumcarboxamide bromide
  • 3-Diethylcarbamoyl-1-octyl-pyridinium
  • MLS000587365
  • SMR000211415

Targets

Known targets for this compound

Species Target name Source Bibliographic reference
Homo sapiens lamin A/C Starlite/ChEMBL No references
Photinus pyralis Luciferin 4-monooxygenase Starlite/ChEMBL No references
Homo sapiens geminin, DNA replication inhibitor Starlite/ChEMBL No references
Homo sapiens APEX nuclease (multifunctional DNA repair enzyme) 1 Starlite/ChEMBL No references

Predicted pathogen targets for this compound

By orthology
Species Potential target Known druggable target/s Ortholog Group
Mycobacterium tuberculosis Fatty-acid-AMP ligase FadD30 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) Get druggable targets OG5_126609 All targets in OG5_126609
Brugia malayi exodeoxyribonuclease III family protein Get druggable targets OG5_126768 All targets in OG5_126768
Chlamydia trachomatis acylglycerophosphoethanolamine acyltransferase Get druggable targets OG5_126609 All targets in OG5_126609
Mycobacterium tuberculosis Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) Get druggable targets OG5_126768 All targets in OG5_126768
Mycobacterium ulcerans fatty-acid-CoA ligase Get druggable targets OG5_126609 All targets in OG5_126609
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_126609 All targets in OG5_126609
Leishmania major apurinic/apyrimidinic endonuclease-redox protein Get druggable targets OG5_126768 All targets in OG5_126768
Loa Loa (eye worm) exodeoxyribonuclease III family protein Get druggable targets OG5_126768 All targets in OG5_126768
Plasmodium yoelii putative AP endonuclease-related Get druggable targets OG5_126768 All targets in OG5_126768
Schistosoma mansoni intermediate filament proteins Get druggable targets OG5_128723 All targets in OG5_128723
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD5 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) Get druggable targets OG5_126609 All targets in OG5_126609
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase Get druggable targets OG5_126768 All targets in OG5_126768
Echinococcus granulosus cytoplasmic intermediate filament protein Get druggable targets OG5_128723 All targets in OG5_128723
Onchocerca volvulus Get druggable targets OG5_126609 All targets in OG5_126609
Entamoeba histolytica acyl-CoA synthetase, putative Get druggable targets OG5_126609 All targets in OG5_126609
Schistosoma mansoni lamin Get druggable targets OG5_128723 All targets in OG5_128723
Leishmania mexicana 4-coumarate:coa ligase-like protein Get druggable targets OG5_126609 All targets in OG5_126609
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative Get druggable targets OG5_126768 All targets in OG5_126768
Leishmania donovani apurinic/apyrimidinic endonuclease-redox protein Get druggable targets OG5_126768 All targets in OG5_126768
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_126609 All targets in OG5_126609
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_128723 All targets in OG5_128723
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_128723 All targets in OG5_128723
Onchocerca volvulus Get druggable targets OG5_128723 All targets in OG5_128723
Neospora caninum hypothetical protein Get druggable targets OG5_126768 All targets in OG5_126768
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD7 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) Get druggable targets OG5_126609 All targets in OG5_126609
Mycobacterium ulcerans acyl-CoA synthetase Get druggable targets OG5_126609 All targets in OG5_126609
Giardia lamblia Endonuclease/Exonuclease/phosphatase Get druggable targets OG5_126768 All targets in OG5_126768
Entamoeba histolytica acyl-CoA synthetase, putative Get druggable targets OG5_126609 All targets in OG5_126609
Echinococcus granulosus lamin Get druggable targets OG5_128723 All targets in OG5_128723
Leishmania infantum 4-coumarate:coa ligase-like protein Get druggable targets OG5_126609 All targets in OG5_126609
Leishmania mexicana 4-coumarate:coa ligase-like protein Get druggable targets OG5_126609 All targets in OG5_126609
Leishmania infantum 4-coumarate:coa ligase-like protein Get druggable targets OG5_126609 All targets in OG5_126609
Echinococcus multilocularis lamin dm0 Get druggable targets OG5_128723 All targets in OG5_128723
Brugia malayi AMP-binding enzyme family protein Get druggable targets OG5_126609 All targets in OG5_126609
Theileria parva hypothetical protein Get druggable targets OG5_126768 All targets in OG5_126768
Plasmodium vivax acyl-CoA synthetase, putative Get druggable targets OG5_126609 All targets in OG5_126609
Leishmania infantum 4-coumarate:coa ligase-like protein Get druggable targets OG5_126609 All targets in OG5_126609
Mycobacterium ulcerans long-chain fatty-acid CoA ligase Get druggable targets OG5_126609 All targets in OG5_126609
Echinococcus multilocularis cytoplasmic intermediate filament protein Get druggable targets OG5_128723 All targets in OG5_128723
Echinococcus granulosus intermediate filament protein Get druggable targets OG5_128723 All targets in OG5_128723
Schistosoma japonicum expressed protein Get druggable targets OG5_128723 All targets in OG5_128723
Plasmodium vivax AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative Get druggable targets OG5_126768 All targets in OG5_126768
Treponema pallidum exodeoxyribonuclease (exoA) Get druggable targets OG5_126768 All targets in OG5_126768
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD2 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) Get druggable targets OG5_126609 All targets in OG5_126609
Schistosoma japonicum expressed protein Get druggable targets OG5_128723 All targets in OG5_128723
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_126609 All targets in OG5_126609
Mycobacterium ulcerans hypothetical protein Get druggable targets OG5_126609 All targets in OG5_126609
Plasmodium knowlesi acyl-CoA synthetase, putative Get druggable targets OG5_126609 All targets in OG5_126609
Brugia malayi Intermediate filament tail domain containing protein Get druggable targets OG5_128723 All targets in OG5_128723
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_126609 All targets in OG5_126609
Plasmodium berghei acyl-CoA synthetase, putative Get druggable targets OG5_126609 All targets in OG5_126609
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_128723 All targets in OG5_128723
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_126609 All targets in OG5_126609
Brugia malayi AMP-binding enzyme family protein Get druggable targets OG5_126609 All targets in OG5_126609
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_126609 All targets in OG5_126609
Echinococcus granulosus lamin dm0 Get druggable targets OG5_128723 All targets in OG5_128723
Candida albicans similar to S. cerevisiae APN2 (YBL019W) DNA repair apurinic/apyrimidinic endonuclease Get druggable targets OG5_126768 All targets in OG5_126768
Mycobacterium ulcerans acyl-CoA synthetase Get druggable targets OG5_126609 All targets in OG5_126609
Schistosoma mansoni ap endonuclease Get druggable targets OG5_126768 All targets in OG5_126768
Echinococcus multilocularis musashi Get druggable targets OG5_128723 All targets in OG5_128723
Cryptosporidium parvum conserved hypothetical protein Get druggable targets OG5_126768 All targets in OG5_126768
Leishmania braziliensis 4-coumarate:coa ligase-like protein Get druggable targets OG5_126609 All targets in OG5_126609
Entamoeba histolytica exodeoxyribonuclease III, putative Get druggable targets OG5_126768 All targets in OG5_126768
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_126609 All targets in OG5_126609
Entamoeba histolytica acyl-coA synthetase, putative Get druggable targets OG5_126609 All targets in OG5_126609
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_126609 All targets in OG5_126609
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase Get druggable targets OG5_126768 All targets in OG5_126768
Loa Loa (eye worm) intermediate filament tail domain-containing protein Get druggable targets OG5_128723 All targets in OG5_128723
Leishmania major 4-coumarate:coa ligase-like protein Get druggable targets OG5_126609 All targets in OG5_126609
Trypanosoma congolense apurinic/apyrimidinic endonuclease, putative Get druggable targets OG5_126768 All targets in OG5_126768
Brugia malayi AMP-binding enzyme family protein Get druggable targets OG5_126609 All targets in OG5_126609
Plasmodium berghei AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative Get druggable targets OG5_126768 All targets in OG5_126768
Schistosoma japonicum DNA-(apurinic or apyrimidinic site) lyase 2, putative Get druggable targets OG5_126768 All targets in OG5_126768
Schistosoma japonicum DNA-(apurinic or apyrimidinic site) lyase 2, putative Get druggable targets OG5_126768 All targets in OG5_126768
Trichomonas vaginalis ap endonuclease, putative Get druggable targets OG5_126768 All targets in OG5_126768
Leishmania infantum 4-coumarate:coa ligase-like protein Get druggable targets OG5_126609 All targets in OG5_126609
Schistosoma mansoni ap endonuclease Get druggable targets OG5_126768 All targets in OG5_126768
Leishmania major 4-coumarate:coa ligase-like protein Get druggable targets OG5_126609 All targets in OG5_126609
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_128723 All targets in OG5_128723
Trypanosoma cruzi apurinic/apyrimidinic endonuclease Get druggable targets OG5_126768 All targets in OG5_126768
Mycobacterium ulcerans long-chain-fatty-acid-CoA ligase Get druggable targets OG5_126609 All targets in OG5_126609
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD35 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) Get druggable targets OG5_126609 All targets in OG5_126609
Plasmodium falciparum AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative Get druggable targets OG5_126768 All targets in OG5_126768
Trichomonas vaginalis ap endonuclease, putative Get druggable targets OG5_126768 All targets in OG5_126768
Schistosoma japonicum ko:K07611 lamin, putative Get druggable targets OG5_128723 All targets in OG5_128723
Echinococcus multilocularis lamin Get druggable targets OG5_128723 All targets in OG5_128723
Mycobacterium ulcerans fatty-acid-CoA ligase Get druggable targets OG5_126609 All targets in OG5_126609
Schistosoma mansoni lamin Get druggable targets OG5_128723 All targets in OG5_128723
Wolbachia endosymbiont of Brugia malayi exonuclease III Get druggable targets OG5_126768 All targets in OG5_126768
Schistosoma japonicum Lamin-C, putative Get druggable targets OG5_128723 All targets in OG5_128723
Leishmania major 4-coumarate:coa ligase-like protein Get druggable targets OG5_126609 All targets in OG5_126609
Leishmania donovani 4-coumarate:coa ligase-like protein Get druggable targets OG5_126609 All targets in OG5_126609
Mycobacterium tuberculosis Probable chain -fatty-acid-CoA ligase FadD13 (fatty-acyl-CoA synthetase) Get druggable targets OG5_126609 All targets in OG5_126609
Mycobacterium ulcerans acyl-CoA synthetase Get druggable targets OG5_126609 All targets in OG5_126609
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD2 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) Get druggable targets OG5_126609 All targets in OG5_126609
Loa Loa (eye worm) intermediate filament protein Get druggable targets OG5_128723 All targets in OG5_128723
Trypanosoma brucei gambiense apurinic/apyrimidinic endonuclease, putative Get druggable targets OG5_126768 All targets in OG5_126768
Candida albicans similar to S. cerevisiae APN2 (YBL019W) DNA repair apurinic/apyrimidinic endonuclease Get druggable targets OG5_126768 All targets in OG5_126768
Toxoplasma gondii exonuclease III APE Get druggable targets OG5_126768 All targets in OG5_126768
Plasmodium yoelii peroxisomal-coenzyme a synthetase Get druggable targets OG5_126609 All targets in OG5_126609
Leishmania donovani 4-coumarate:coa ligase-like protein Get druggable targets OG5_126609 All targets in OG5_126609
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_128723 All targets in OG5_128723
Brugia malayi intermediate filament protein Get druggable targets OG5_128723 All targets in OG5_128723
Cryptosporidium hominis dna-(apurinic or apyrimidinic site) lyase Get druggable targets OG5_126768 All targets in OG5_126768
Plasmodium knowlesi AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative Get druggable targets OG5_126768 All targets in OG5_126768
Leishmania infantum apurinic/apyrimidinic endonuclease-redox protein Get druggable targets OG5_126768 All targets in OG5_126768
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative Get druggable targets OG5_126768 All targets in OG5_126768
Schistosoma japonicum Intermediate filament protein ifa-1, putative Get druggable targets OG5_128723 All targets in OG5_128723
Schistosoma japonicum ko:K10772 AP endonuclease 2, putative Get druggable targets OG5_126768 All targets in OG5_126768
Leishmania braziliensis apurinic/apyrimidinic endonuclease-redox protein Get druggable targets OG5_126768 All targets in OG5_126768
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD7 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) Get druggable targets OG5_126609 All targets in OG5_126609
Leishmania mexicana apurinic/apyrimidinic endonuclease-redox protein,AP-endonuclease Get druggable targets OG5_126768 All targets in OG5_126768
Mycobacterium ulcerans long-chain-fatty-acid--CoA ligase Get druggable targets OG5_126609 All targets in OG5_126609
Onchocerca volvulus Get druggable targets OG5_128723 All targets in OG5_128723
Schistosoma japonicum ko:K10771 AP endonuclease 1, putative Get druggable targets OG5_126768 All targets in OG5_126768
Plasmodium falciparum acyl-CoA synthetase Get druggable targets OG5_126609 All targets in OG5_126609
Leishmania mexicana 4-coumarate:coa ligase-like protein Get druggable targets OG5_126609 All targets in OG5_126609
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD3 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) Get druggable targets OG5_126609 All targets in OG5_126609
Mycobacterium ulcerans exodeoxyribonuclease III protein XthA Get druggable targets OG5_126768 All targets in OG5_126768
By sequence similarity to non orthologous known druggable targets
Species Potential target Known druggable target Length Alignment span Identity
Dictyostelium discoideum hypothetical protein Luciferin 4-monooxygenase   550 aa 542 aa 22.1 %
Dictyostelium discoideum hypothetical protein Luciferin 4-monooxygenase   550 aa 541 aa 21.4 %
Mycobacterium ulcerans fatty-acid-CoA ligase FadD9 Luciferin 4-monooxygenase   550 aa 463 aa 21.8 %
Mycobacterium ulcerans long-chain-fatty-acid-CoA ligase FadD15 Luciferin 4-monooxygenase   550 aa 482 aa 24.3 %
Mycobacterium ulcerans fatty-acid-CoA ligase FadD11 Luciferin 4-monooxygenase   550 aa 498 aa 23.5 %
Mycobacterium ulcerans non-ribosomal peptide synthetase Luciferin 4-monooxygenase   550 aa 541 aa 22.4 %
Schistosoma mansoni FAA1 Long-chain-fatty-acid--CoA ligase 1 Luciferin 4-monooxygenase   550 aa 494 aa 26.3 %
Trichomonas vaginalis antibiotic synthetase, putative Luciferin 4-monooxygenase   550 aa 581 aa 21.2 %
Cryptosporidium hominis acetyl-CoenzymeA synthetase (acetate--coa ligase) (acyl-activating enzyme) Luciferin 4-monooxygenase   550 aa 549 aa 22.6 %
Mycobacterium ulcerans non-ribosomal peptide synthetase MbtE Luciferin 4-monooxygenase   550 aa 502 aa 22.5 %
Trichomonas vaginalis AMP dependent ligase, putative Luciferin 4-monooxygenase   550 aa 445 aa 26.1 %
Echinococcus multilocularis long chain fatty acid coenzyme A ligase 5 Luciferin 4-monooxygenase   550 aa 458 aa 25.5 %
Mycobacterium tuberculosis Fatty-acid-AMP ligase FadD28 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) Luciferin 4-monooxygenase   550 aa 504 aa 22.6 %
Trypanosoma brucei fatty acyl CoA synthetase 3 Luciferin 4-monooxygenase   550 aa 491 aa 23.6 %
Trichomonas vaginalis AMP dependent ligase/synthetase, putative Luciferin 4-monooxygenase   550 aa 476 aa 23.5 %
Dictyostelium discoideum hypothetical protein Luciferin 4-monooxygenase   550 aa 522 aa 19.9 %
Echinococcus granulosus long chain fatty acid coenzyme A ligase 5 Luciferin 4-monooxygenase   550 aa 458 aa 25.8 %
Leishmania infantum long chain fatty Acyl CoA synthetase, putative Luciferin 4-monooxygenase   550 aa 500 aa 23.4 %
Cryptosporidium parvum acyl-CoA synthetase Luciferin 4-monooxygenase   550 aa 460 aa 25.7 %
Mycobacterium tuberculosis Probable fatty-acid-AMP ligase FadD23 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) Luciferin 4-monooxygenase   550 aa 542 aa 23.8 %
Dictyostelium discoideum hypothetical protein Luciferin 4-monooxygenase   550 aa 539 aa 19.1 %
Candida albicans similar to S. cerevisiae FAA4 (YMR246W) long-chain fatty acid--CoA synthetase Luciferin 4-monooxygenase   550 aa 478 aa 23.4 %
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD8 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) Luciferin 4-monooxygenase   550 aa 505 aa 28.1 %
Entamoeba histolytica acyl-CoA synthetase, putative Luciferin 4-monooxygenase   550 aa 446 aa 22.0 %
Mycobacterium tuberculosis Fatty-acid-AMP ligase FadD26 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) Luciferin 4-monooxygenase   550 aa 560 aa 21.4 %
Dictyostelium discoideum hypothetical protein Luciferin 4-monooxygenase   550 aa 538 aa 21.8 %
Toxoplasma gondii propionate-CoA ligase Luciferin 4-monooxygenase   550 aa 550 aa 21.1 %
Leishmania braziliensis long chain fatty Acyl CoA synthetase, putative Luciferin 4-monooxygenase   550 aa 496 aa 22.8 %
Trichomonas vaginalis long-chain-fatty-acid CoA ligase, putative Luciferin 4-monooxygenase   550 aa 466 aa 21.7 %
Mycobacterium ulcerans acyl-CoA synthetase Luciferin 4-monooxygenase   550 aa 530 aa 23.8 %
Dictyostelium discoideum hypothetical protein Luciferin 4-monooxygenase   550 aa 538 aa 21.8 %
Dictyostelium discoideum hypothetical protein Luciferin 4-monooxygenase   550 aa 576 aa 19.8 %
Trichomonas vaginalis AMP dependent CoA ligase, putative Luciferin 4-monooxygenase   550 aa 492 aa 23.6 %
Brugia malayi AMP-binding enzyme family protein Luciferin 4-monooxygenase   550 aa 544 aa 21.5 %
Leishmania mexicana acetyl-CoA synthetase, putative Luciferin 4-monooxygenase   550 aa 559 aa 20.6 %
Onchocerca volvulus Luciferin 4-monooxygenase   550 aa 487 aa 23.8 %
Dictyostelium discoideum hypothetical protein Luciferin 4-monooxygenase   550 aa 463 aa 23.5 %
Entamoeba histolytica long-chain-fatty-acid--CoA ligase, putative Luciferin 4-monooxygenase   550 aa 480 aa 21.5 %
Mycobacterium leprae Probable fatty-acid-CoA ligase FadD9 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) Luciferin 4-monooxygenase   550 aa 461 aa 22.3 %
Candida albicans similar to S. cerevisiae FAT1 (YBR041W) fatty acid transporter and very long-chain fatty acyl-CoA synthetase Luciferin 4-monooxygenase   550 aa 496 aa 24.2 %
Mycobacterium leprae Probable fatty-acid-CoA synthetase FadD22 (fatty-acid-CoA ligase) (fatty-acid-CoA synthase) Luciferin 4-monooxygenase   550 aa 493 aa 20.7 %
Trichomonas vaginalis AMP dependent CoA ligase, putative Luciferin 4-monooxygenase   550 aa 524 aa 24.0 %
Leishmania mexicana long chain fatty Acyl CoA synthetase, putative Luciferin 4-monooxygenase   550 aa 483 aa 23.8 %
Mycobacterium ulcerans acyl-CoA synthetase Luciferin 4-monooxygenase   550 aa 582 aa 22.3 %
Cryptosporidium hominis acyl-CoA synthetase Luciferin 4-monooxygenase   550 aa 460 aa 26.1 %
Trypanosoma cruzi fatty acyl CoA synthetase, putative Luciferin 4-monooxygenase   550 aa 480 aa 25.2 %
Mycobacterium leprae Probable fatty-acid-CoA synthetase FadD29 (fatty-acid-CoA ligase) (fatty-acid-CoA synthase) Luciferin 4-monooxygenase   550 aa 529 aa 22.3 %
Cryptosporidium parvum acetyl-coenzyme A synthetase Luciferin 4-monooxygenase   550 aa 545 aa 22.8 %
Dictyostelium discoideum hypothetical protein Luciferin 4-monooxygenase   550 aa 558 aa 20.4 %
Cryptosporidium parvum putative long chain fatty acyl CoA synthetase having a signal peptide Luciferin 4-monooxygenase   550 aa 472 aa 24.8 %
Echinococcus granulosus long chain fatty acid transport protein 4 Luciferin 4-monooxygenase   550 aa 476 aa 22.3 %
Dictyostelium discoideum hypothetical protein Luciferin 4-monooxygenase   550 aa 542 aa 18.3 %
Dictyostelium discoideum hypothetical protein Luciferin 4-monooxygenase   550 aa 541 aa 21.6 %
Babesia bovis fatty acyl-CoA synthetase family protein Luciferin 4-monooxygenase   550 aa 461 aa 23.4 %
Mycobacterium tuberculosis Fatty-acid-AMP ligase FadD29 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) Luciferin 4-monooxygenase   550 aa 617 aa 22.2 %
Mycobacterium leprae FATTY-ACID-CoA LIGASE FADD26 (FATTY-ACID-COA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) Luciferin 4-monooxygenase   550 aa 533 aa 22.7 %
Mycobacterium leprae PROBABLE FATTY-ACID--CoA LIGASE FADD21 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) Luciferin 4-monooxygenase   550 aa 565 aa 22.8 %
Dictyostelium discoideum hypothetical protein Luciferin 4-monooxygenase   550 aa 541 aa 21.6 %
Dictyostelium discoideum AMP-dependent synthetase and ligase domain-containing protein Luciferin 4-monooxygenase   550 aa 517 aa 24.8 %
Echinococcus granulosus long chain fatty acid coenzyme A ligase 1 Luciferin 4-monooxygenase   550 aa 452 aa 26.1 %
Candida albicans similar to S. cerevisiae ACS2 (YLR153C) acetyl-CoA synthetase Luciferin 4-monooxygenase   550 aa 539 aa 22.1 %
Dictyostelium discoideum hypothetical protein Luciferin 4-monooxygenase   550 aa 535 aa 21.7 %
Mycobacterium leprae Probable fatty-acid-CoA synthetase FadD32 (fatty-acid-CoA ligase) (fatty-acid-CoA synthase) Luciferin 4-monooxygenase   550 aa 442 aa 23.5 %
Dictyostelium discoideum AMP-dependent synthetase and ligase domain-containing protein Luciferin 4-monooxygenase   550 aa 545 aa 24.9 %
Onchocerca volvulus Matrilysin homolog Luciferin 4-monooxygenase   550 aa 466 aa 24.2 %
Mycobacterium tuberculosis P-hydroxybenzoyl-AMP ligase FadD22 Luciferin 4-monooxygenase   550 aa 493 aa 22.1 %
Dictyostelium discoideum AMP-dependent synthetase and ligase domain-containing protein Luciferin 4-monooxygenase   550 aa 531 aa 19.0 %
Mycobacterium ulcerans long-chain-fatty-acid-CoA ligase, FadD11 Luciferin 4-monooxygenase   550 aa 492 aa 24.6 %
Mycobacterium leprae Probable long-chain-fatty-acid-CoA ligase FadD15 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) Luciferin 4-monooxygenase   550 aa 484 aa 23.3 %
Mycobacterium leprae Probable fatty-acid-CoA synthetase FadD28 (fatty-acid-CoA ligase) (fatty-acid-CoA synthase) Luciferin 4-monooxygenase   550 aa 484 aa 20.5 %
Mycobacterium tuberculosis Bifunctional enzyme MbtA: salicyl-AMP ligase (SAL-AMP ligase) + salicyl-S-ArCP synthetase Luciferin 4-monooxygenase   550 aa 536 aa 24.4 %
Candida albicans similar to S. cerevisiae FAT1 (YBR041W) fatty acid transporter and very long-chain fatty acyl-CoA synthetase Luciferin 4-monooxygenase   550 aa 496 aa 24.2 %
Echinococcus multilocularis long chain fatty acid coenzyme A ligase 1 Luciferin 4-monooxygenase   550 aa 459 aa 27.0 %
Onchocerca volvulus Luciferin 4-monooxygenase   550 aa 502 aa 24.9 %
Mycobacterium ulcerans long-chain-fatty-acid--CoA ligase Luciferin 4-monooxygenase   550 aa 509 aa 21.8 %
Leishmania braziliensis acetyl-CoA synthetase, putative Luciferin 4-monooxygenase   550 aa 596 aa 21.1 %
Mycobacterium tuberculosis Probable acyl-CoA ligase FadD31 (acyl-CoA synthetase) (acyl-CoA synthase) Luciferin 4-monooxygenase   550 aa 592 aa 20.4 %
Trichomonas vaginalis long-chain-fatty-acid CoA ligase, putative Luciferin 4-monooxygenase   550 aa 490 aa 23.3 %
Schistosoma japonicum ko:K08745 solute carrier family 27 (fatty acid transporter), member 1, putative Luciferin 4-monooxygenase   550 aa 501 aa 24.6 %
Neospora caninum acetyl-coenzyme a synthetase, putative Luciferin 4-monooxygenase   550 aa 549 aa 20.9 %
Mycobacterium ulcerans acyl-CoA synthetase Luciferin 4-monooxygenase   550 aa 601 aa 22.5 %
Trichomonas vaginalis AMP dependent ligase/synthetase, putative Luciferin 4-monooxygenase   550 aa 494 aa 24.3 %
Leishmania braziliensis acetyl-CoA synthetase, putative Luciferin 4-monooxygenase   550 aa 603 aa 22.6 %
Dictyostelium discoideum fatty acyl-CoA synthetase Luciferin 4-monooxygenase   550 aa 501 aa 24.4 %
Entamoeba histolytica long-chain-fatty-acid--CoA ligase, putative Luciferin 4-monooxygenase   550 aa 494 aa 23.9 %
Trichomonas vaginalis antibiotic synthetase, putative Luciferin 4-monooxygenase   550 aa 577 aa 22.2 %
Schistosoma japonicum ko:K01897 long-chain fatty-acid-CoA ligase [EC6.2.1.3], putative Luciferin 4-monooxygenase   550 aa 466 aa 27.3 %
Dictyostelium discoideum hypothetical protein Luciferin 4-monooxygenase   550 aa 542 aa 18.3 %
Trypanosoma brucei gambiense fatty acyl CoA synthetase 4, putative Luciferin 4-monooxygenase   550 aa 497 aa 23.7 %
Mycobacterium tuberculosis Probable fatty-acid-AMP ligase FadD21 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) Luciferin 4-monooxygenase   550 aa 586 aa 24.4 %
Echinococcus multilocularis long chain fatty acid transport protein 4 Luciferin 4-monooxygenase   550 aa 476 aa 22.3 %
Schistosoma japonicum ko:K01897 long-chain fatty-acid-CoA ligase [EC6.2.1.3], putative Luciferin 4-monooxygenase   550 aa 541 aa 22.4 %
Echinococcus multilocularis long chain fatty acid coenzyme A ligase 1 Luciferin 4-monooxygenase   550 aa 443 aa 26.4 %
Mycobacterium ulcerans long-chain-fatty-acid-CoA ligase FadD15 Luciferin 4-monooxygenase   550 aa 484 aa 26.0 %
Trichomonas vaginalis AMP dependent ligase/synthetase, putative Luciferin 4-monooxygenase   550 aa 554 aa 22.9 %
Babesia bovis long-chain acyl-CoA synthetase, putative Luciferin 4-monooxygenase   550 aa 445 aa 21.8 %
Dictyostelium discoideum hypothetical protein Luciferin 4-monooxygenase   550 aa 542 aa 22.1 %
Dictyostelium discoideum hypothetical protein Luciferin 4-monooxygenase   550 aa 535 aa 22.6 %
Trichomonas vaginalis AMP dependent ligase/synthetase, putative Luciferin 4-monooxygenase   550 aa 526 aa 22.4 %
Candida albicans similar to S. cerevisiae ACS2 (YLR153C) acetyl-CoA synthetase Luciferin 4-monooxygenase   550 aa 539 aa 22.1 %
Dictyostelium discoideum hypothetical protein Luciferin 4-monooxygenase   550 aa 478 aa 21.1 %
Trichomonas vaginalis AMP dependent ligase/synthetase, putative Luciferin 4-monooxygenase   550 aa 554 aa 24.4 %
Dictyostelium discoideum AMP-dependent synthetase and ligase domain-containing protein Luciferin 4-monooxygenase   550 aa 550 aa 20.9 %
Dictyostelium discoideum hypothetical protein Luciferin 4-monooxygenase   550 aa 507 aa 20.9 %
Dictyostelium discoideum fatty acyl-CoA synthetase Luciferin 4-monooxygenase   550 aa 462 aa 23.8 %
Mycobacterium ulcerans peptide synthetase Nrp (peptide synthase) Luciferin 4-monooxygenase   550 aa 535 aa 23.2 %
Mycobacterium ulcerans acyl-CoA synthetase Luciferin 4-monooxygenase   550 aa 497 aa 19.3 %
Mycobacterium tuberculosis Probable fatty-acid-AMP ligase FadD24 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) Luciferin 4-monooxygenase   550 aa 526 aa 21.9 %
Candida albicans similar to S. cerevisiae ACS2 (YLR153C) acetyl-CoA synthetase Luciferin 4-monooxygenase   550 aa 543 aa 24.5 %
Leishmania donovani long chain fatty Acyl CoA synthetase, putative Luciferin 4-monooxygenase   550 aa 500 aa 23.4 %
Trichomonas vaginalis AMP dependent CoA ligase, putative Luciferin 4-monooxygenase   550 aa 527 aa 25.0 %
Mycobacterium ulcerans putative fatty-acid--CoA ligase Luciferin 4-monooxygenase   550 aa 576 aa 20.8 %
Candida albicans similar to S. cerevisiae ACS2 (YLR153C) acetyl-CoA synthetase Luciferin 4-monooxygenase   550 aa 543 aa 24.5 %
Mycobacterium ulcerans acyl-CoA synthetase Luciferin 4-monooxygenase   550 aa 593 aa 22.1 %
Brugia malayi AMP-binding enzyme family protein Luciferin 4-monooxygenase   550 aa 497 aa 24.7 %
Onchocerca volvulus Lysine-specific histone demethylase 1A homolog Luciferin 4-monooxygenase   550 aa 550 aa 22.5 %
Mycobacterium ulcerans non-ribosomal peptide synthetase MbtF Luciferin 4-monooxygenase   550 aa 558 aa 20.1 %
Mycobacterium tuberculosis Probable peptide synthetase Nrp (peptide synthase) Luciferin 4-monooxygenase   550 aa 509 aa 22.6 %
Mycobacterium tuberculosis Fatty-acid-AMP ligase FadD32 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase). Also shown to have acyl-ACP ligase activity. Luciferin 4-monooxygenase   550 aa 487 aa 22.4 %
Dictyostelium discoideum hypothetical protein Luciferin 4-monooxygenase   550 aa 539 aa 19.1 %
Loa Loa (eye worm) AMP-binding enzyme family protein Luciferin 4-monooxygenase   550 aa 489 aa 23.3 %
Dictyostelium discoideum hypothetical protein Luciferin 4-monooxygenase   550 aa 522 aa 19.9 %
Leishmania braziliensis long-chain-fatty-acid-CoA ligase, putative Luciferin 4-monooxygenase   550 aa 504 aa 25.6 %
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein Luciferin 4-monooxygenase   550 aa 476 aa 22.5 %
Brugia malayi Hypothetical 65.5 kDa Trp-Asp repeats containing protein F02E8.5 inchromosome X geminin, DNA replication inhibitor 209 aa 176 aa 27.8 %
Entamoeba histolytica long-chain-fatty-acid--CoA ligase, putative Luciferin 4-monooxygenase   550 aa 476 aa 20.8 %
Dictyostelium discoideum hypothetical protein Luciferin 4-monooxygenase   550 aa 541 aa 21.4 %
Dictyostelium discoideum acetyl-CoA ligase Luciferin 4-monooxygenase   550 aa 549 aa 22.2 %
Trypanosoma congolense fatty acyl CoA synthetase 2, putative Luciferin 4-monooxygenase   550 aa 500 aa 22.4 %
Trypanosoma cruzi fatty acyl CoA synthetase 2, putative Luciferin 4-monooxygenase   550 aa 495 aa 22.6 %
Leishmania major long chain fatty Acyl CoA synthetase, putative Luciferin 4-monooxygenase   550 aa 482 aa 23.2 %
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD9 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) Luciferin 4-monooxygenase   550 aa 480 aa 22.5 %
Mycobacterium tuberculosis Probable fatty-acid-AMP ligase FadD25 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) Luciferin 4-monooxygenase   550 aa 475 aa 21.1 %
Dictyostelium discoideum hypothetical protein Luciferin 4-monooxygenase   550 aa 499 aa 19.2 %
Trypanosoma brucei gambiense fatty acyl CoA synthetase 3 Luciferin 4-monooxygenase   550 aa 491 aa 23.6 %
Trypanosoma cruzi fatty acyl CoA synthetase, putative Luciferin 4-monooxygenase   550 aa 482 aa 24.7 %
Theileria parva long-chain fatty acid CoA ligase, putative Luciferin 4-monooxygenase   550 aa 507 aa 23.5 %
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD34 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) Luciferin 4-monooxygenase   550 aa 537 aa 20.9 %
Toxoplasma gondii type I fatty acid synthase, putative Luciferin 4-monooxygenase   550 aa 514 aa 19.8 %
Neospora caninum Short-chain dehydrogenase/reductase SDR, related Luciferin 4-monooxygenase   550 aa 518 aa 19.1 %
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Trichomonas vaginalis glucosylceramidase, putative 0.0278 0.0216 0.4537
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.0181 0.0136 0.0136
Schistosoma mansoni growth hormone secretagogue receptor 0.0021 0.0004 0.0004
Loa Loa (eye worm) hypothetical protein 0.0021 0.0004 0.0004
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription factor 0.0084 0.0056 0.0056
Mycobacterium leprae Probable fructose bisphosphate aldolase Fba 0.0289 0.0226 0.4936
Onchocerca volvulus 0.0023 0.0006 0.0078
Schistosoma mansoni hypothetical protein 0.0348 0.0274 0.0274
Echinococcus multilocularis histone acetyltransferase MYST2 0.0053 0.0031 0.0031
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0048 0.0027 0.0027
Echinococcus granulosus Peptidase C19 ubiquitin carboxyl terminal hydrolase 2 0.0045 0.0024 0.0024
Loa Loa (eye worm) mbt repeat family protein 0.0047 0.0026 0.0026
Brugia malayi hypothetical protein 0.0021 0.0004 0.0004
Loa Loa (eye worm) hypothetical protein 0.0021 0.0004 0.0004
Brugia malayi CXXC zinc finger family protein 0.0058 0.0035 0.0035
Loa Loa (eye worm) hypothetical protein 0.0091 0.0062 0.0062
Trypanosoma cruzi short chain dehydrogenase/reductase, putative 0.0023 0.0006 0.0008
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0069 0.0044 0.0058
Brugia malayi orphan nuclear receptor NR2E1 0.0085 0.0058 0.0058
Loa Loa (eye worm) hypothetical protein 0.0066 0.0041 0.0041
Echinococcus multilocularis heat shock protein 90 0.0079 0.0052 0.0052
Loa Loa (eye worm) DOMON domain-containing protein 0.0018 0.0002 0.0002
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0023 0.0006 0.0006
Echinococcus granulosus L aminoadipate semialdehyde 0.0595 0.0478 0.0478
Trichomonas vaginalis short-chain dehydrogenase, putative 0.0023 0.0006 0.0127
Mycobacterium leprae conserved hypothetical protein 0.0032 0.0014 0.0286
Brugia malayi Regulator of G protein signaling domain containing protein 0.0021 0.0004 0.0004
Leishmania major heat shock protein 83-1 0.0095 0.0065 0.0087
Onchocerca volvulus 0.0159 0.0118 0.1987
Loa Loa (eye worm) hypothetical protein 0.0021 0.0004 0.0004
Schistosoma mansoni muscarinic acetylcholine (GAR) receptor 0.0021 0.0004 0.0004
Loa Loa (eye worm) hypothetical protein 0.0021 0.0004 0.0004
Loa Loa (eye worm) hypothetical protein 0.0181 0.0136 0.0136
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0023 0.0006 0.0006
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0021 0.0004 0.0004
Mycobacterium ulcerans short chain dehydrogenase 0.0023 0.0006 0.0132
Toxoplasma gondii ICE family protease (caspase) p20 domain-containing protein 0.0091 0.0062 0.0062
Echinococcus multilocularis 3 hydroxyacyl coenzyme A dehydrogenase type 2 0.0189 0.0143 0.0143
Trichomonas vaginalis PIKK family atypical protein kinase 0.0026 0.0009 0.0175
Trichomonas vaginalis PIKK family atypical protein kinase 0.0026 0.0009 0.0174
Toxoplasma gondii 4'-phosphopantetheinyl transferase domain-containing protein 0.0167 0.0125 0.0125
Echinococcus granulosus heat shock protein 0.0095 0.0065 0.0065
Brugia malayi tailless protein 0.0085 0.0058 0.0058
Mycobacterium ulcerans short chain dehydrogenase 0.0023 0.0006 0.0132
Brugia malayi Probable G protein-coupled receptor kinase F19C6.1, putative 0.0022 0.0006 0.0006
Treponema pallidum exodeoxyribonuclease (exoA) 0.0023 0.0006 0.0117
Mycobacterium tuberculosis Probable oxidoreductase 0.0023 0.0006 0.0132
Loa Loa (eye worm) CMGC/MAPK/ERK1 protein kinase 0.0051 0.0029 0.0029
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0021 0.0004 0.0004
Treponema pallidum NADH oxidase 0.0046 0.0025 0.0527
Brugia malayi hypothetical protein 0.0084 0.0057 0.0057
Trypanosoma brucei target of rapamycin kinase 3, putative 0.0038 0.0019 0.0025
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0023 0.0006 0.0006
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0016 0.0001 0.0001
Onchocerca volvulus Mothers against decapentaplegic homolog 0.0019 0.0003 0.0014
Toxoplasma gondii ATP-binding cassette G family transporter ABCG84 0.002 0.0004 0.0003
Echinococcus granulosus ferritin 0.0035 0.0016 0.0016
Mycobacterium ulcerans short-chain dehydrogenase 0.0023 0.0006 0.0132
Brugia malayi Dopamine receptor 0.0021 0.0004 0.0004
Echinococcus multilocularis rhodopsin orphan GPCR 0.0021 0.0004 0.0004
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0023 0.0006 0.0132
Entamoeba histolytica FKBP-rapamycin associated protein (FRAP), putative 0.0048 0.0027 0.0527
Echinococcus granulosus cytochrome P450 2K1 0.0019 0.0003 0.0003
Mycobacterium ulcerans transmembrane ABC transporter ATP-binding protein 0.002 0.0004 0.0071
Trypanosoma cruzi hypothetical protein, conserved 0.0023 0.0006 0.0008
Trypanosoma cruzi STE group serine/threonine-protein kinase, putative 0.0086 0.0059 0.0078
Loa Loa (eye worm) hypothetical protein 0.0021 0.0004 0.0004
Echinococcus multilocularis epidermal retinal dehydrogenase 2 0.0023 0.0006 0.0006
Trypanosoma cruzi STE group serine/threonine-protein kinase, putative 0.0086 0.0059 0.0078
Echinococcus multilocularis ecdysone induced protein 78C 0.0181 0.0136 0.0136
Echinococcus multilocularis conserved hypothetical protein 0.0742 0.0598 0.0598
Trypanosoma cruzi DNA damage repair protein, putative 0.0023 0.0006 0.0008
Schistosoma mansoni dishevelled 0.0018 0.0002 0.0002
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0069 0.0044 0.0058
Brugia malayi Melibiase family protein 0.014 0.0103 0.0103
Schistosoma mansoni hypothetical protein 0.1214 0.0988 0.0988
Trypanosoma brucei DNA polymerase kappa, putative 0.0101 0.0071 0.0095
Trichomonas vaginalis glucosylceramidase, putative 0.0182 0.0137 0.2881
Schistosoma mansoni serine/threonine protein kinase 0.0195 0.0148 0.0148
Plasmodium vivax vivapain-2 0.0018 0.0002 0.0002
Onchocerca volvulus 0.0018 0.0002 0.0003
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0091 0.0062 0.1298
Trypanosoma brucei oxidoreductase-like protein 0.0023 0.0006 0.0008
Echinococcus granulosus kelch ECH associated protein 1 like 0.0094 0.0065 0.0065
Schistosoma mansoni biogenic amine (5HT) receptor 0.0021 0.0004 0.0004
Loa Loa (eye worm) hypothetical protein 0.0031 0.0013 0.0013
Treponema pallidum DNA topoisomerase I (topA) 0.0301 0.0235 0.4942
Schistosoma mansoni Smad4 0.0042 0.0022 0.0022
Plasmodium falciparum flap endonuclease 1 0.0027 0.001 0.0009
Echinococcus granulosus axis inhibition protein axin 0.0021 0.0004 0.0004
Echinococcus multilocularis cytoplasmic intermediate filament protein 0.0027 0.001 0.001
Trypanosoma cruzi heat shock protein, putative 0.0053 0.0031 0.0041
Trypanosoma cruzi 2,4-dihydroxyhept-2-ene-1,7-dioic acid aldolase, putative 0.0026 0.0009 0.0011
Echinococcus granulosus cathepsin L cysteine proteinase 0.0018 0.0002 0.0002
Brugia malayi MH2 domain containing protein 0.0616 0.0494 0.0494
Entamoeba histolytica hypothetical protein 0.033 0.0259 0.5426
Brugia malayi GRF zinc finger family protein 0.0066 0.0041 0.0041
Plasmodium falciparum ABC transporter G family member 2 0.002 0.0004 0.0003
Schistosoma mansoni biogenic amine (5HT) receptor 0.0021 0.0004 0.0004
Schistosoma mansoni DNA topoisomerase II 0.0074 0.0049 0.0049
Trypanosoma brucei DNA polymerase kappa, putative 0.005 0.0029 0.0038
Trypanosoma brucei DNA polymerase IV, putative 0.0095 0.0065 0.0087
Trypanosoma cruzi DNA topoisomerase III, putative 0.0265 0.0205 0.0276
Trichomonas vaginalis soluble guanylate cyclase gcy, putative 0.0085 0.0057 0.1195
Echinococcus granulosus nuclear receptor subfamily 4 group A 0.0085 0.0058 0.0058
Loa Loa (eye worm) hypothetical protein 0.0019 0.0003 0.0003
Brugia malayi hypothetical protein 0.0023 0.0006 0.0006
Schistosoma mansoni endoplasmin 0.0095 0.0065 0.0065
Brugia malayi Bromodomain containing protein 0.0018 0.0002 0.0002
Schistosoma mansoni terminal deoxycytidyl transferase 0.0074 0.0048 0.0048
Loa Loa (eye worm) hypothetical protein 0.0018 0.0002 0.0002
Loa Loa (eye worm) hypothetical protein 0.0096 0.0066 0.0066
Leishmania major cathepsin L-like protease 0.0018 0.0002 0.0002
Mycobacterium tuberculosis Probable shortchain dehydrogenase 0.0023 0.0006 0.0132
Onchocerca volvulus 0.0021 0.0004 0.004
Toxoplasma gondii inositol(myo)-1(or 4)-monophosphatase 2, putative 0.0117 0.0083 0.0083
Echinococcus granulosus Transcription factor JmjC domain containing protein 0.0221 0.0169 0.0169
Trichomonas vaginalis ap endonuclease, putative 0.0023 0.0006 0.0117
Trypanosoma cruzi metacaspase 5, putative 0.0091 0.0062 0.0083
Echinococcus multilocularis Transcription factor, JmjC domain containing protein 0.0221 0.0169 0.0169
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0046 0.0025 0.0034
Loa Loa (eye worm) GTP-binding nuclear protein RAN/TC4 0.0022 0.0006 0.0006
Brugia malayi hypoxia-induced factor 1 0.0919 0.0745 0.0745
Plasmodium vivax DNA gyrase subunit B, putative 0.0074 0.0049 0.0048
Mycobacterium tuberculosis Probable short-chain dehydrogenase/reductase 0.0023 0.0006 0.0132
Loa Loa (eye worm) hypothetical protein 0.0021 0.0004 0.0004
Brugia malayi hypothetical protein 0.033 0.0259 0.0259
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0046 0.0025 0.0034
Loa Loa (eye worm) hypothetical protein 0.0021 0.0004 0.0004
Leishmania major heat shock protein 83-1 0.0095 0.0065 0.0087
Echinococcus multilocularis gcn5proteinral control of amino acid synthesis 0.0604 0.0485 0.0485
Echinococcus granulosus neuropeptide Y receptor 0.0021 0.0004 0.0004
Leishmania major heat shock protein 83-1 0.0095 0.0065 0.0087
Schistosoma mansoni smad1 5 8 and 0.0042 0.0022 0.0022
Loa Loa (eye worm) hypothetical protein 0.0019 0.0003 0.0003
Toxoplasma gondii heat shock protein 90, putative 0.0095 0.0065 0.0065
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0181 0.0136 0.0136
Trypanosoma brucei ATP-binding cassette protein, putative 0.002 0.0004 0.0004
Echinococcus granulosus apoptotic protease activating factor 1 0.0085 0.0057 0.0057
Trypanosoma cruzi beta-ketoacyl-ACP reductase 2, putative 0.0023 0.0006 0.0008
Loa Loa (eye worm) hypothetical protein 0.0085 0.0058 0.0058
Schistosoma mansoni ferritin 0.0035 0.0016 0.0016
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0085 0.0058 0.0951
Schistosoma mansoni coup transcription factor 0.0181 0.0136 0.0136
Loa Loa (eye worm) hypothetical protein 0.0045 0.0024 0.0024
Echinococcus multilocularis lamin dm0 0.0056 0.0033 0.0033
Echinococcus multilocularis L aminoadipate semialdehyde 0.0595 0.0478 0.0478
Loa Loa (eye worm) hypothetical protein 0.0021 0.0004 0.0004
Trypanosoma cruzi hypothetical protein, conserved 0.0069 0.0044 0.0058
Leishmania major lanosterol 14-alpha-demethylase, putative 0.0019 0.0003 0.0003
Mycobacterium tuberculosis Putative ferredoxin reductase 0.0305 0.0239 0.5223
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0046 0.0025 0.0034
Loa Loa (eye worm) cytoplasmic intermediate filament protein 0.003 0.0012 0.0012
Entamoeba histolytica Flap nuclease, putative 0.0027 0.001 0.0163
Loa Loa (eye worm) CYP4Cod1 0.0046 0.0025 0.0025
Mycobacterium tuberculosis NADPH-dependent mycothiol reductase Mtr 0.0134 0.0098 0.2128
Trichomonas vaginalis PIKK family atypical protein kinase 0.0016 0.0001 0.0004
Wolbachia endosymbiont of Brugia malayi fructose-1,6-bisphosphatase 0.0117 0.0083 0.3531
Schistosoma mansoni nuclear receptor 0.0085 0.0058 0.0058
Schistosoma mansoni regulator of G protein signaling 17 19 20 (rgs17 19 20) 0.0021 0.0004 0.0004
Schistosoma mansoni serine/threonine protein kinase 0.0181 0.0136 0.0136
Trichomonas vaginalis adenylate and guanylate cyclases, putative 0.0085 0.0057 0.1195
Trypanosoma cruzi metacaspase, putative 0.0091 0.0062 0.0083
Echinococcus granulosus ubiquitin specific protease 41 0.0045 0.0024 0.0024
Echinococcus multilocularis g protein coupled receptor 0.0021 0.0004 0.0004
Echinococcus multilocularis mitogen activated protein kinase 3 0.0051 0.0029 0.0029
Onchocerca volvulus Dehydrogenase\/reductase SDR family member 13 homolog 0.0023 0.0006 0.0078
Echinococcus granulosus heat shock protein 90 0.0095 0.0065 0.0065
Trichomonas vaginalis PIKK family atypical protein kinase 0.0026 0.0009 0.0174
Brugia malayi AMP-binding enzyme family protein 0.0029 0.0011 0.0011
Echinococcus multilocularis cathepsin L cysteine protease 0.0018 0.0002 0.0002
Loa Loa (eye worm) hypothetical protein 0.0021 0.0004 0.0004
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.0018 0.0002 0.0002
Echinococcus multilocularis kelch ECH associated protein 1 0.0094 0.0065 0.0065
Echinococcus multilocularis G protein coupled 5 hydroxytryptamine receptor 0.0021 0.0004 0.0004
Trypanosoma cruzi hypothetical protein, conserved 0.0023 0.0006 0.0008
Loa Loa (eye worm) hypothetical protein 0.0029 0.0011 0.0011
Schistosoma mansoni jumonji/arid domain-containing protein 0.0164 0.0122 0.0122
Echinococcus multilocularis oxidoreductase 0.0023 0.0006 0.0006
Echinococcus granulosus dnaJ subfamily B 0.0825 0.0667 0.0667
Trichomonas vaginalis ran, putative 0.0022 0.0006 0.011
Trichomonas vaginalis ap endonuclease, putative 0.0023 0.0006 0.0117
Trypanosoma brucei DNA polymerase kappa, putative 0.0101 0.0071 0.0095
Echinococcus granulosus endonuclease exonuclease phosphatase 0.0188 0.0142 0.0142
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0021 0.0004 0.0004
Toxoplasma gondii glycosyl hydrolase, family 31 protein 0.0084 0.0057 0.0056
Brugia malayi F/Y-rich N-terminus family protein 0.003 0.0012 0.0012
Mycobacterium tuberculosis Probable oxidoreductase 0.0023 0.0006 0.0132
Onchocerca volvulus 0.0027 0.0009 0.0123
Toxoplasma gondii DNA topoisomerase 2, putative 0.0074 0.0049 0.0048
Echinococcus granulosus neuropeptide Y receptor 0.0021 0.0004 0.0004
Mycobacterium ulcerans short-chain type oxidoreductase 0.0023 0.0006 0.0132
Loa Loa (eye worm) hypothetical protein 0.0085 0.0058 0.0058
Entamoeba histolytica DNA topoisomerase III, putative 0.0257 0.0199 0.4165
Loa Loa (eye worm) hypothetical protein 0.0041 0.0021 0.0021
Trichomonas vaginalis PIKK family atypical protein kinase 0.0032 0.0014 0.0285
Brugia malayi O-Glycosyl hydrolase family 30 protein 0.0278 0.0216 0.0216
Mycobacterium ulcerans dehydratase 0.0081 0.0054 0.1173
Echinococcus multilocularis kelch ECH associated protein 1 0.0094 0.0065 0.0065
Mycobacterium ulcerans long-chain fatty-acid CoA ligase 0.0029 0.0011 0.0228
Echinococcus multilocularis MAM 0.0019 0.0003 0.0003
Giardia lamblia Endonuclease/Exonuclease/phosphatase 0.0023 0.0006 0.0117
Trypanosoma cruzi NAD(P)-dependent oxidoreductase, putative 0.0023 0.0006 0.0008
Leishmania major short chain dehydrogenase/reductase, putative 0.0023 0.0006 0.0008
Trypanosoma brucei DNA polymerase kappa, putative 0.0101 0.0071 0.0095
Schistosoma mansoni peptide (FMRFamide/neurokinin-3)-like receptor 0.0021 0.0004 0.0004
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0096 0.0066 0.0066
Echinococcus multilocularis Niemann Pick C1 protein 0.0137 0.01 0.01
Onchocerca volvulus 0.0023 0.0006 0.0078
Echinococcus granulosus survival motor neuron protein 1 0.1461 0.1191 0.1191
Echinococcus multilocularis somatostatin receptor 0.0021 0.0004 0.0004
Brugia malayi Serotonin receptor 0.0021 0.0004 0.0004
Mycobacterium tuberculosis Probable oxidoreductase 0.0023 0.0006 0.0132
Leishmania major mitogen activated protein kinase, putative,map kinase, putative 0.0051 0.0029 0.0039
Loa Loa (eye worm) hypothetical protein 0.0018 0.0002 0.0002
Echinococcus multilocularis nuclear receptor nhr 48 0.0085 0.0058 0.0058
Echinococcus granulosus 3 hydroxyacyl coenzyme A dehydrogenase type 2 0.0189 0.0143 0.0143
Loa Loa (eye worm) unidentified vitellogenin-linked transcript protein 6 0.0021 0.0004 0.0004
Leishmania major hypothetical protein, conserved 0.0131 0.0095 0.0127
Leishmania major DNA topoisomerase IB, large subunit 0.9025 0.7422 1
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0021 0.0004 0.0004
Schistosoma mansoni nuclear receptor 0.0085 0.0058 0.0058
Leishmania major hypothetical protein, conserved 0.0023 0.0006 0.0008
Onchocerca volvulus 0.0018 0.0002 0.0003
Loa Loa (eye worm) hypothetical protein 0.0169 0.0127 0.0127
Loa Loa (eye worm) hypothetical protein 0.0085 0.0058 0.0058
Schistosoma mansoni gcn5proteinral control of amino-acid synthesis 5-like 2 gcnl2 0.0604 0.0485 0.0485
Giardia lamblia DNA damage repair protein 0.0023 0.0006 0.0122
Echinococcus granulosus thyroid hormone receptor alpha 0.0085 0.0058 0.0058
Mycobacterium ulcerans short chain dehydrogenase 0.0023 0.0006 0.0132
Trypanosoma cruzi hypothetical protein, conserved 0.0069 0.0044 0.0058
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0069 0.0044 0.0058
Brugia malayi Probable DNA topoisomerase II 0.0074 0.0049 0.0049
Mycobacterium tuberculosis Cytochrome P450 51 Cyp51 (CYPL1) (P450-L1A1) (sterol 14-alpha demethylase) (lanosterol 14-alpha demethylase) (P450-14DM) 0.0019 0.0003 0.0049
Trichomonas vaginalis PIKK family atypical protein kinase 0.0029 0.0011 0.0223
Echinococcus multilocularis ATP binding cassette sub family G 0.002 0.0004 0.0004
Brugia malayi hypothetical protein 0.0021 0.0004 0.0004
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.0181 0.0136 0.0136
Echinococcus multilocularis TRP (transient receptor potential) channel 0.0072 0.0047 0.0047
Giardia lamblia Fructose-bisphosphate aldolase 0.0592 0.0475 1
Trypanosoma brucei FAT domain/Rapamycin binding domain/Phosphatidylinositol 3- and 4-kinase, putative 0.002 0.0004 0.0005
Schistosoma mansoni Smad4 0.0019 0.0003 0.0003
Echinococcus multilocularis estradiol 17 beta dehydrogenase 12 0.0023 0.0006 0.0006
Mycobacterium ulcerans citrate (pro-3S)-lyase subunit beta 0.0026 0.0009 0.0177
Schistosoma mansoni ubiquitin-specific peptidase 2 (C19 family) 0.0045 0.0024 0.0024
Schistosoma mansoni neuropeptide receptor 0.0021 0.0004 0.0004
Schistosoma mansoni axis inhibition protein axin 0.0021 0.0004 0.0004
Loa Loa (eye worm) hypothetical protein 0.0127 0.0092 0.0091
Trypanosoma brucei DNA polymerase kappa, putative 0.0101 0.0071 0.0095
Loa Loa (eye worm) ImpB/MucB/SamB family protein 0.0074 0.0048 0.0048
Onchocerca volvulus 0.0021 0.0004 0.004
Schistosoma mansoni short chain dehydrogenase 0.0023 0.0006 0.0006
Leishmania major apurinic/apyrimidinic endonuclease-redox protein 0.0023 0.0006 0.0007
Entamoeba histolytica estradiol 17-beta-dehydrogenase, putative 0.0023 0.0006 0.0093
Echinococcus multilocularis microtubule associated protein 2 0.2077 0.1698 0.1698
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0023 0.0006 0.0006
Leishmania major heat shock protein 83-1 0.0095 0.0065 0.0087
Loa Loa (eye worm) hypothetical protein 0.0085 0.0058 0.0058
Loa Loa (eye worm) oxidoreductase 0.0023 0.0006 0.0006
Brugia malayi nuclear hormone receptor family member odr-7 0.0085 0.0058 0.0058
Trypanosoma brucei metacaspase MCA2 0.0091 0.0062 0.0083
Trypanosoma brucei DNA topoisomerase III, putative 0.0134 0.0098 0.0131
Schistosoma mansoni ferritin 0.0035 0.0016 0.0016
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.0018 0.0002 0.0035
Mycobacterium ulcerans heat shock protein 90 0.0083 0.0056 0.1213
Trichomonas vaginalis regulator of G protein signaling 5, rgs5, putative 0.0021 0.0004 0.008
Echinococcus granulosus regulator of G protein signaling 3 0.0021 0.0004 0.0004
Giardia lamblia GTOR 0.0048 0.0027 0.056
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0019 0.0003 0.0003
Schistosoma mansoni steroid dehydrogenase 0.0023 0.0006 0.0006
Mycobacterium tuberculosis Probable short-chain type dehydrogenase/reductase 0.0023 0.0006 0.0132
Loa Loa (eye worm) hypothetical protein 0.005 0.0029 0.0029
Loa Loa (eye worm) oxidoreductase 0.0023 0.0006 0.0006
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0018 0.0002 0.0035
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.0018 0.0002 0.0035
Schistosoma mansoni steroid dehydrogenase 0.0023 0.0006 0.0006
Brugia malayi Domain found in Dishevelled, Egl-10, and Pleckstrin family protein 0.0018 0.0002 0.0002
Schistosoma mansoni cathepsin F (C01 family) 0.0018 0.0002 0.0002
Toxoplasma gondii pyruvate dehydrogenase complex subunit PDH-E3II 0.0046 0.0025 0.0025
Trypanosoma cruzi DNA topoisomerase III, putative 0.0134 0.0098 0.0131
Brugia malayi Pre-SET motif family protein 0.0064 0.004 0.004
Trypanosoma brucei heat shock protein, putative 0.0095 0.0065 0.0087
Trichomonas vaginalis Citrate lyase beta chain, putative 0.0026 0.0009 0.017
Echinococcus multilocularis retinol dehydrogenase 13 0.0023 0.0006 0.0006
Mycobacterium ulcerans putative regulatory protein 0.022 0.0168 0.368
Leishmania major target of rapamycin (TOR) kinase 1, putative 0.0048 0.0027 0.0036
Echinococcus granulosus rhodopsin orphan GPCR 0.0021 0.0004 0.0004
Loa Loa (eye worm) hypothetical protein 0.0023 0.0006 0.0006
Brugia malayi Intermediate filament tail domain containing protein 0.0056 0.0033 0.0033
Loa Loa (eye worm) hypothetical protein 0.0047 0.0026 0.0026
Echinococcus multilocularis serine:threonine protein kinase PLK1 0.0195 0.0148 0.0148
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0064 0.004 0.004
Trypanosoma cruzi 3-ketoacyl-CoA reductase, putative 0.0023 0.0006 0.0008
Echinococcus multilocularis peptide (allatostatin:somatostatin) 0.0021 0.0004 0.0004
Onchocerca volvulus 0.0027 0.0009 0.0123
Echinococcus multilocularis dro:myosuppressin receptor 0.0021 0.0004 0.0004
Echinococcus granulosus ATP binding cassette sub family G 0.002 0.0004 0.0004
Trichomonas vaginalis PIKK family atypical protein kinase 0.0038 0.0019 0.0389
Loa Loa (eye worm) melatonin receptor type 1A 0.0021 0.0004 0.0004
Brugia malayi jmjC domain containing protein 0.0164 0.0122 0.0122
Entamoeba histolytica hypothetical protein 0.033 0.0259 0.5426
Schistosoma mansoni aldehyde dehydrogenase 0.0191 0.0145 0.0145
Plasmodium falciparum AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0023 0.0006 0.0006
Loa Loa (eye worm) hypoxia-induced factor 1 0.0919 0.0745 0.0744
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0181 0.0136 0.0136
Loa Loa (eye worm) helix-loop-helix DNA-binding domain-containing protein 0.0018 0.0002 0.0002
Echinococcus multilocularis jumonji domain containing protein 0.0041 0.0021 0.0021
Brugia malayi Nuclear hormone receptor family member nhr-1 0.0181 0.0136 0.0136
Mycobacterium tuberculosis Probable reductase 0.0305 0.0239 0.5223
Echinococcus multilocularis caspase 8 0.0091 0.0062 0.0062
Loa Loa (eye worm) hypothetical protein 0.0053 0.0031 0.0031
Trichomonas vaginalis heat shock protein, putative 0.0064 0.004 0.0837
Trypanosoma cruzi hypothetical protein, conserved 0.0084 0.0057 0.0076
Loa Loa (eye worm) hypothetical protein 0.1162 0.0945 0.0944
Onchocerca volvulus Dehydrogenase\/reductase SDR family member 13 homolog 0.0023 0.0006 0.0078
Brugia malayi SCP-2 sterol transfer family protein 0.0032 0.0013 0.0013
Toxoplasma gondii carbonyl reductase 1, putative 0.0023 0.0006 0.0006
Echinococcus granulosus Alpha N acetylgalactosaminidase 0.021 0.016 0.016
Entamoeba histolytica short chain dehydrogenase family protein 0.0023 0.0006 0.0093
Brugia malayi jmjC domain containing protein 0.0221 0.0169 0.0169
Leishmania major heat shock protein 83-1 0.0095 0.0065 0.0087
Echinococcus granulosus tyrosyl DNA phosphodiesterase 1 0.0068 0.0043 0.0043
Trypanosoma brucei DNA damage repair protein, putative 0.0023 0.0006 0.0008
Loa Loa (eye worm) hypothetical protein 0.0018 0.0002 0.0002
Echinococcus multilocularis endoplasmin 0.0083 0.0056 0.0056
Brugia malayi Tachykinin-like peptides receptor 99D 0.0021 0.0004 0.0004
Trichomonas vaginalis short-chain dehydrogenase, putative 0.0023 0.0006 0.0127
Entamoeba histolytica short chain dehydrogenase family protein 0.0023 0.0006 0.0093
Schistosoma mansoni steroid dehydrogenase 0.0023 0.0006 0.0006
Schistosoma mansoni hypothetical protein 0.0021 0.0004 0.0004
Trypanosoma brucei Vps23 core domain containing protein, putative 0.0022 0.0006 0.0007
Echinococcus multilocularis nuclear receptor subfamily 1 group D 0.0096 0.0066 0.0066
Trypanosoma cruzi DNA topoisomerase IB, large subunit, putative 0.9025 0.7422 1
Mycobacterium tuberculosis UDP-galactopyranose mutase Glf (UDP-GALP mutase) (NAD+-flavin adenine dinucleotide-requiring enzyme) 0.057 0.0457 1
Loa Loa (eye worm) hypothetical protein 0.0023 0.0006 0.0006
Mycobacterium tuberculosis Probable membrane NADH dehydrogenase NdhA 0.0305 0.0239 0.5223
Brugia malayi CUB domain containing protein 0.0016 0.0001 0.0001
Trichomonas vaginalis alpha-glucosidase, putative 0.0031 0.0013 0.0266
Mycobacterium tuberculosis Probable conserved transmembrane ATP-binding protein ABC transporter 0.0017 0.0001 0.0012
Mycobacterium leprae conserved hypothetical protein 0.0032 0.0014 0.0286
Trichomonas vaginalis prokaryotic DNA topoisomerase, putative 0.0257 0.0199 0.4185
Echinococcus multilocularis 0.0019 0.0003 0.0003
Trypanosoma brucei DNA damage repair protein, putative 0.0023 0.0006 0.0008
Echinococcus granulosus serine:threonine protein kinase PLK1 0.0195 0.0148 0.0148
Echinococcus multilocularis neuropeptides capa receptor 0.0021 0.0004 0.0004
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0021 0.0004 0.0004
Echinococcus granulosus kelch ECH associated protein 1 like 0.0094 0.0065 0.0065
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0064 0.004 0.004
Trypanosoma cruzi cruzipain precursor, putative 0.0069 0.0044 0.0058
Schistosoma mansoni hypothetical protein 0.0095 0.0065 0.0065
Leishmania major short chain dehydrogenase/reductase, putative 0.0023 0.0006 0.0008
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0025 0.0008 0.0149
Loa Loa (eye worm) cysteine protease 0.0018 0.0002 0.0002
Trypanosoma cruzi tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0068 0.0043 0.0058
Echinococcus granulosus biogenic amine 5HT receptor 0.0021 0.0004 0.0004
Echinococcus multilocularis expressed protein 0.0401 0.0318 0.0318
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0023 0.0006 0.0132
Echinococcus multilocularis nuclear receptor subfamily 4 group A 0.0085 0.0058 0.0058
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0018 0.0002 0.0035
Brugia malayi ImpB/MucB/SamB family protein 0.0074 0.0048 0.0048
Plasmodium vivax SET domain containing protein 0.0018 0.0002 0.0002
Trypanosoma cruzi heat shock protein 85, putative 0.0095 0.0065 0.0087
Schistosoma mansoni amine GPCR 0.0021 0.0004 0.0004
Loa Loa (eye worm) jmjC domain-containing protein 0.0043 0.0022 0.0022
Onchocerca volvulus 0.0018 0.0002 0.0004
Mycobacterium ulcerans 4'-phosphopantetheinyl transferase 0.0167 0.0125 0.2733
Brugia malayi Calcitonin receptor-like protein seb-1 0.006 0.0037 0.0037
Trichomonas vaginalis hypothetical protein 0.0034 0.0015 0.0311
Mycobacterium leprae Probable UDP-galactopyranose mutase Glf (UDP-galp mutase) (NAD+-flavin adenine dinucleotide-requiring enzyme) 0.057 0.0457 1
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0046 0.0025 0.0034
Echinococcus multilocularis serotonin receptor 0.0021 0.0004 0.0004
Mycobacterium tuberculosis Probable short-chain type oxidoreductase 0.0023 0.0006 0.0132
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0021 0.0004 0.0004
Brugia malayi D-beta-hydroxybutyrate dehydrogenase, mitochondrial precursor 0.0023 0.0006 0.0006
Loa Loa (eye worm) PXA domain-containing protein 0.0021 0.0004 0.0004
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD5 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.002 0.0004 0.0076
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0097 0.0067 0.0067
Schistosoma mansoni regulator of G protein signaling 0.0021 0.0004 0.0004
Loa Loa (eye worm) oxidoreductase 0.0055 0.0033 0.0033
Mycobacterium leprae Possible regulatory protein 0.0085 0.0057 0.1244
Loa Loa (eye worm) glycosyl hydrolase family 31 protein 0.0319 0.025 0.025
Loa Loa (eye worm) hypothetical protein 0.0023 0.0006 0.0006
Schistosoma mansoni hypothetical protein 0.0019 0.0003 0.0003
Trypanosoma cruzi heat shock protein 85, putative 0.0079 0.0052 0.0069
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0592 0.0475 1
Trypanosoma brucei hypothetical protein, conserved 0.0023 0.0006 0.0008
Echinococcus multilocularis musashi 0.0056 0.0033 0.0033
Echinococcus multilocularis thioredoxin glutathione reductase 0.0134 0.0098 0.0098
Brugia malayi bZIP transcription factor family protein 0.0084 0.0056 0.0056
Trypanosoma brucei heat shock protein 90, putative 0.0095 0.0065 0.0087
Loa Loa (eye worm) hypothetical protein 0.0021 0.0004 0.0004
Toxoplasma gondii oxidoreductase, short chain dehydrogenase/reductase family protein 0.0023 0.0006 0.0006
Brugia malayi RE15519p 0.0021 0.0004 0.0004
Trichomonas vaginalis CAMK family protein kinase 0.0097 0.0067 0.1404
Entamoeba histolytica Acid sphingomyelinase-like phosphodiesterase, putative 0.0169 0.0127 0.2637
Trichomonas vaginalis PIKK family atypical protein kinase 0.0031 0.0013 0.0266
Plasmodium vivax glutathione reductase, putative 0.0134 0.0098 0.0097
Brugia malayi Latrophilin receptor protein 2 0.0019 0.0003 0.0003
Trypanosoma cruzi cytochrome P450, putative 0.0046 0.0025 0.0033
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0181 0.0136 0.0136
Echinococcus multilocularis apoptotic protease activating factor 1 0.0085 0.0057 0.0057
Toxoplasma gondii 2,4-dienoyl CoA reductase 2, peroxisomal family protein 0.0023 0.0006 0.0006
Mycobacterium ulcerans cytochrome P450 105Q4 Cyp105Q4 0.0019 0.0003 0.0049
Loa Loa (eye worm) hypothetical protein 0.0096 0.0066 0.0066
Echinococcus multilocularis Ataxin 2, N terminal,domain containing protein 0.0059 0.0036 0.0036
Mycobacterium tuberculosis Probable cytochrome P450 124 Cyp124 0.0019 0.0003 0.0049
Plasmodium falciparum cysteine proteinase falcipain 2a 0.0018 0.0002 0.0002
Trypanosoma cruzi polo-like protein kinase, putative 0.0195 0.0148 0.0199
Trichomonas vaginalis PIKK family atypical protein kinase 0.0048 0.0027 0.056
Echinococcus granulosus regulator of G protein signaling 3 0.0021 0.0004 0.0004
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.0181 0.0136 0.0136
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0023 0.0006 0.0006
Brugia malayi G-protein coupled receptor 0.0021 0.0004 0.0004
Echinococcus multilocularis cpg binding protein 0.0061 0.0038 0.0038
Giardia lamblia GTP-binding nuclear protein RAN/TC4 0.0022 0.0006 0.011
Leishmania major heat shock protein 83-1 0.0095 0.0065 0.0087
Schistosoma mansoni ferritin 0.0035 0.0016 0.0016
Loa Loa (eye worm) G-protein-linked acetylcholine receptor protein 2 0.0021 0.0004 0.0004
Echinococcus granulosus intermediate filament protein 0.0056 0.0033 0.0033
Onchocerca volvulus 0.0181 0.0136 0.2296
Onchocerca volvulus Neuropeptide F receptor homolog 0.0021 0.0004 0.004
Schistosoma mansoni tsg101-related 0.0047 0.0026 0.0026
Brugia malayi MH2 domain containing protein 0.0019 0.0003 0.0003
Brugia malayi Pax transcription factor protein 2 0.0729 0.0588 0.0588
Echinococcus granulosus ATP binding cassette sub family G 0.002 0.0004 0.0004
Loa Loa (eye worm) TK/ALK protein kinase 0.0019 0.0003 0.0003
Echinococcus granulosus polycomb protein SCMH1 0.0047 0.0026 0.0026
Loa Loa (eye worm) hypothetical protein 0.0021 0.0005 0.0005
Mycobacterium tuberculosis Probable cytochrome P450 136 Cyp136 0.0019 0.0003 0.0049
Schistosoma mansoni steroid dehydrogenase 0.0023 0.0006 0.0006
Leishmania major heat shock protein 83-1 0.0095 0.0065 0.0087
Leishmania major cathepsin L-like protease 0.0018 0.0002 0.0002
Giardia lamblia Oxidoreductase, short chain dehydrogenase/reductase family 0.0023 0.0006 0.0127
Echinococcus multilocularis tumor susceptibility gene 101 protein 0.007 0.0045 0.0045
Toxoplasma gondii oxidoreductase, short chain dehydrogenase/reductase family protein 0.0023 0.0006 0.0006
Echinococcus multilocularis G-protein coupled receptor, putative 0.0021 0.0004 0.0004
Trypanosoma cruzi DNA polymerase eta, putative 0.0075 0.0049 0.0066
Schistosoma mansoni aldehyde dehydrogenase 0.0191 0.0145 0.0145
Loa Loa (eye worm) hypothetical protein 0.0019 0.0003 0.0003
Mycobacterium tuberculosis Probable monooxygenase 0.0027 0.0009 0.019
Plasmodium vivax thioredoxin reductase, putative 0.0134 0.0098 0.0097
Loa Loa (eye worm) oxidoreductase 0.0023 0.0006 0.0006
Trichomonas vaginalis conserved hypothetical protein 0.0091 0.0062 0.1298
Toxoplasma gondii ICE family protease (caspase) p20 domain-containing protein 0.0091 0.0062 0.0062
Trichomonas vaginalis PIKK family atypical protein kinase 0.0036 0.0017 0.0346
Onchocerca volvulus 0.0729 0.0588 1
Mycobacterium ulcerans short chain dehydrogenase 0.0023 0.0006 0.0132
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0021 0.0004 0.0004
Trypanosoma brucei protein kinase, putative 0.0051 0.0029 0.0039
Loa Loa (eye worm) hypothetical protein 0.0085 0.0058 0.0058
Mycobacterium leprae Probable DNA topoisomerase I TopA (omega-protein) (relaxing enzyme) (untwisting enzyme) (swivelase) (type I DNA topoisomerase) ( 0.0257 0.0199 0.4355
Echinococcus granulosus expressed protein 0.0035 0.0016 0.0016
Schistosoma mansoni bromodomain-containing nuclear protein 1 brd1 0.0029 0.0011 0.0011
Mycobacterium tuberculosis Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras 0.0339 0.0267 0.5838
Trichomonas vaginalis heat shock protein, putative 0.0048 0.0027 0.056
Mycobacterium tuberculosis DNA gyrase (subunit B) GyrB (DNA topoisomerase (ATP-hydrolysing)) (DNA topoisomerase II) (type II DNA topoisomerase) 0.0074 0.0049 0.1053
Leishmania major protein kinase, putative 0.0086 0.0059 0.0078
Trypanosoma brucei DNA topoisomerase III, putative 0.0265 0.0205 0.0276
Echinococcus multilocularis Glycoside hydrolase, family 27 0.021 0.016 0.016
Leishmania major dehydrogenase-like protein 0.0023 0.0006 0.0008
Echinococcus granulosus tumor susceptibility gene 101 protein 0.007 0.0045 0.0045
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0061 0.0038 0.0038
Mycobacterium ulcerans 3-alpha-hydroxysteroid dehydrogenase 0.0023 0.0006 0.0132
Echinococcus granulosus carbonyl reductase 1 0.0023 0.0006 0.0006
Schistosoma mansoni ferritin light chain 0.0035 0.0016 0.0016
Trypanosoma brucei DNA polymerase eta, putative 0.0127 0.0092 0.0123
Trypanosoma brucei Metacaspase-4 0.0091 0.0062 0.0083
Schistosoma mansoni hypothetical protein 0.0029 0.0011 0.0011
Loa Loa (eye worm) hypothetical protein 0.0021 0.0004 0.0004
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.0181 0.0136 0.0136
Mycobacterium ulcerans short chain dehydrogenase 0.0023 0.0006 0.0132
Toxoplasma gondii heat shock protein 75, putative 0.0053 0.0031 0.003
Trypanosoma brucei ubiquitin carboxyl-terminal hydrolase, putative 0.0045 0.0024 0.0032
Giardia lamblia NADH oxidase lateral transfer candidate 0.0046 0.0025 0.0527
Toxoplasma gondii isocitrate dehydrogenase 0.0097 0.0067 0.0067
Brugia malayi sulfakinin receptor protein 0.0021 0.0004 0.0004
Schistosoma mansoni ran 0.0022 0.0006 0.0006
Trypanosoma cruzi cytochrome p450-like protein, putative 0.0019 0.0003 0.0003
Brugia malayi Cytochrome P450 family protein 0.0046 0.0025 0.0025
Plasmodium falciparum endoplasmin, putative 0.0064 0.004 0.004
Trichomonas vaginalis glucosylceramidase, putative 0.0182 0.0137 0.2881
Schistosoma mansoni short-chain dehydrogenase/reductase 0.0023 0.0006 0.0006
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0439 0.0349 0.0349
Brugia malayi Protein kinase domain containing protein 0.0017 0.0001 0.0001
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0592 0.0475 1
Brugia malayi ecdysteroid receptor 0.0181 0.0136 0.0136
Plasmodium falciparum conserved Plasmodium protein, unknown function 0.0023 0.0006 0.0006
Plasmodium falciparum metacaspase 1 0.0091 0.0062 0.0062
Giardia lamblia Kinase, PLK 0.0195 0.0148 0.3102
Loa Loa (eye worm) hypothetical protein 0.0084 0.0056 0.0056
Leishmania major hypothetical protein, conserved 0.0069 0.0044 0.0058
Mycobacterium ulcerans dihydrolipoamide dehydrogenase, LpdB 0.0046 0.0025 0.0549
Onchocerca volvulus 0.0056 0.0033 0.0537
Trichomonas vaginalis flap endonuclease-1, putative 0.0027 0.001 0.0198
Trichomonas vaginalis glucosylceramidase, putative 0.0278 0.0216 0.4537
Brugia malayi MH2 domain containing protein 0.0042 0.0022 0.0022
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0048 0.0027 0.0027
Loa Loa (eye worm) jmjC domain-containing protein 0.0043 0.0022 0.0022
Echinococcus multilocularis neuropeptide receptor A26 0.0576 0.0462 0.0462
Trypanosoma cruzi PAS-domain containing phosphoglycerate kinase, putative 0.0085 0.0057 0.0076
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0021 0.0004 0.0004
Onchocerca volvulus Sepiapterin reductase homolog 0.0023 0.0006 0.0078
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.0181 0.0136 0.0136
Entamoeba histolytica acyl-CoA synthetase, putative 0.0029 0.0011 0.0185
Schistosoma mansoni regulator of G protein signaling 0.0021 0.0004 0.0004
Schistosoma mansoni amine GPCR 0.0021 0.0004 0.0004
Loa Loa (eye worm) hypothetical protein 0.0021 0.0004 0.0004
Echinococcus multilocularis regulator of G protein signaling 3 0.0021 0.0004 0.0004
Loa Loa (eye worm) jmjC domain-containing protein 0.0164 0.0122 0.0122
Chlamydia trachomatis DNA topoisomerase I 0.0301 0.0235 1
Echinococcus granulosus neuropeptides capa receptor 0.0021 0.0004 0.0004
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0117 0.0083 0.0112
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0018 0.0002 0.0035
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0021 0.0004 0.0004
Echinococcus granulosus peregrin 0.0044 0.0024 0.0024
Onchocerca volvulus 0.0055 0.0033 0.0524
Trypanosoma cruzi oxidoreductase-like protein, putative 0.0023 0.0006 0.0008
Loa Loa (eye worm) hypothetical protein 0.0027 0.001 0.001
Leishmania major target of rapamycin (TOR) kinase 2, putative 0.0048 0.0027 0.0036
Echinococcus granulosus regulator of G protein signaling 7 0.0038 0.0019 0.0019
Loa Loa (eye worm) hypothetical protein 0.0021 0.0004 0.0004
Leishmania major metacaspase, putative 0.0091 0.0062 0.0083
Loa Loa (eye worm) oxidoreductase 0.0023 0.0006 0.0006
Brugia malayi nuclear hormone receptor 0.0181 0.0136 0.0136
Trypanosoma cruzi hypothetical protein, conserved 0.0023 0.0006 0.0008
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative 0.0023 0.0006 0.0007
Onchocerca volvulus 0.0023 0.0006 0.0078
Schistosoma mansoni myoglobin 1 0.0027 0.0009 0.0009
Schistosoma mansoni steroid hormone receptor ad4bp 0.0181 0.0136 0.0136
Loa Loa (eye worm) hypothetical protein 0.0029 0.0011 0.0011
Loa Loa (eye worm) MH2 domain-containing protein 0.0616 0.0494 0.0494
Brugia malayi latrophilin 2 splice variant baaae 0.0041 0.0021 0.0021
Trichomonas vaginalis alpha-glucosidase, putative 0.0031 0.0013 0.0266
Trypanosoma cruzi metacaspase 5, putative 0.0091 0.0062 0.0083
Echinococcus granulosus growth hormone secretagogue receptor type 1 0.0021 0.0004 0.0004
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.0018 0.0002 0.0002
Mycobacterium ulcerans cytochrome P450 143A3 Cyp143A3 0.0019 0.0003 0.0049
Trypanosoma brucei heat shock protein, putative 0.0095 0.0065 0.0087
Trichomonas vaginalis heat shock protein, putative 0.0079 0.0052 0.1086
Entamoeba histolytica acyl-coA synthetase, putative 0.0029 0.0011 0.0185
Schistosoma mansoni nuclear hormone receptor 0.0085 0.0058 0.0058
Echinococcus granulosus histone acetyltransferase KAT2B 0.0178 0.0134 0.0134
Mycobacterium ulcerans short chain dehydrogenase 0.0023 0.0006 0.0132
Onchocerca volvulus 0.0019 0.0003 0.0023
Brugia malayi hypothetical protein 0.0019 0.0003 0.0003
Loa Loa (eye worm) hypothetical protein 0.0056 0.0033 0.0033
Brugia malayi Inositol-1 0.0117 0.0083 0.0083
Loa Loa (eye worm) hypothetical protein 0.0023 0.0006 0.0006
Loa Loa (eye worm) hypothetical protein 0.006 0.0037 0.0037
Trichomonas vaginalis PIKK family atypical protein kinase 0.0048 0.0027 0.056
Loa Loa (eye worm) cytochrome P450 family protein 0.0046 0.0025 0.0025
Echinococcus multilocularis snurportin 1 0.0324 0.0254 0.0254
Echinococcus granulosus flap endonuclease 1 0.0027 0.001 0.001
Onchocerca volvulus 0.0053 0.0031 0.0497
Echinococcus multilocularis short transient receptor potential channel 6 0.0128 0.0093 0.0093
Trichomonas vaginalis PIKK family atypical protein kinase 0.0038 0.0019 0.0389
Echinococcus multilocularis axis inhibition protein axin 0.0021 0.0004 0.0004
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0592 0.0475 1
Echinococcus multilocularis Regulator of G protein signaling 20 0.0021 0.0004 0.0004
Leishmania major cathepsin L-like protease 0.0018 0.0002 0.0002
Echinococcus multilocularis cathepsin L cysteine protease 0.0018 0.0002 0.0002
Trypanosoma brucei DNA polymerase IV, putative 0.0101 0.0071 0.0095
Brugia malayi Domain found in Dishevelled, Egl-10, and Pleckstrin family protein 0.0018 0.0002 0.0002
Schistosoma mansoni hypothetical protein 0.0825 0.0667 0.0667
Echinococcus multilocularis carbonyl reductase 1 0.0023 0.0006 0.0006
Plasmodium falciparum dihydrolipoyl dehydrogenase, mitochondrial 0.0046 0.0025 0.0025
Onchocerca volvulus 0.0021 0.0004 0.004
Echinococcus multilocularis mitogen activated protein kinase 0.0051 0.0029 0.0029
Trichomonas vaginalis conserved hypothetical protein 0.0085 0.0057 0.1195
Schistosoma mansoni neuropeptide F-like receptor 0.0021 0.0004 0.0004
Toxoplasma gondii GTP-binding nuclear protein ran/tc4 0.0022 0.0006 0.0005
Loa Loa (eye worm) hypothetical protein 0.0181 0.0136 0.0136
Trichomonas vaginalis conserved hypothetical protein 0.0085 0.0057 0.1195
Schistosoma mansoni dishevelled 0.0018 0.0002 0.0002
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD7 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.002 0.0004 0.0076
Schistosoma mansoni hypothetical protein 0.0298 0.0233 0.0233
Trypanosoma brucei Heat shock protein 83, putative 0.0095 0.0065 0.0087
Schistosoma mansoni adenoreceptor 0.0021 0.0004 0.0004
Leishmania major 3-oxoacyl-(acyl-carrier protein) reductase, putative 0.0189 0.0143 0.0192
Loa Loa (eye worm) follicle stimulating hormone receptor 0.0021 0.0004 0.0004
Schistosoma mansoni serine/threonine protein kinase 0.0022 0.0006 0.0006
Echinococcus granulosus lysosomal alpha glucosidase 0.0319 0.025 0.025
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.033 0.0259 0.0259
Schistosoma mansoni hypothetical protein 0.004 0.002 0.002
Schistosoma mansoni thyroid hormone receptor 0.0181 0.0136 0.0136
Giardia lamblia DNA topoisomerase II 0.0058 0.0035 0.0735
Trypanosoma cruzi hypothetical protein, conserved 0.0069 0.0044 0.0058
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0023 0.0006 0.0006
Plasmodium vivax histone acetyltransferase GCN5, putative 0.0178 0.0134 0.0133
Entamoeba histolytica DNA topoisomerase II, putative 0.0074 0.0049 0.0981
Echinococcus granulosus histone lysine methyltransferase setb 0.0064 0.004 0.004
Leishmania major flap endonuclease-1 (FEN-1), putative 0.0027 0.001 0.0013
Onchocerca volvulus Rap guanine nucleotide exchange factor 1 homolog 0.0361 0.0285 0.4832
Onchocerca volvulus 0.0023 0.0006 0.0078
Schistosoma mansoni tar DNA-binding protein 0.0129 0.0093 0.0093
Loa Loa (eye worm) DNA topoisomerase III 0.0265 0.0205 0.0205
Echinococcus granulosus Dehydrogenase:reductase SDR family 0.0023 0.0006 0.0006
Schistosoma mansoni biogenic amine (octopamine/dopamine) receptor 0.0021 0.0004 0.0004
Echinococcus granulosus axis inhibition protein axin 0.0021 0.0004 0.0004
Onchocerca volvulus 0.0103 0.0072 0.1197
Loa Loa (eye worm) hypothetical protein 0.0029 0.0011 0.0011
Leishmania major quinonoid dihydropteridine reductase 0.0023 0.0006 0.0008
Trypanosoma cruzi mitochondrial DNA topoisomerase II, putative 0.0074 0.0049 0.0065
Schistosoma mansoni DNA topoisomerase type I 0.9025 0.7422 0.7422
Toxoplasma gondii histone lysine methyltransferase SET1 0.0127 0.0092 0.0091
Onchocerca volvulus 0.0064 0.004 0.0651
Mycobacterium ulcerans hypothetical protein 0.0081 0.0054 0.1173
Loa Loa (eye worm) nuclear hormone receptor 0.0085 0.0058 0.0058
Echinococcus granulosus DNA topoisomerase 3 alpha 0.0265 0.0205 0.0205
Toxoplasma gondii cathepsin CPL 0.0018 0.0002 0.0002
Schistosoma mansoni neuropeptide f receptor 76f 0.0021 0.0004 0.0004
Echinococcus granulosus neuropeptide receptor A26 0.0576 0.0462 0.0462
Trypanosoma cruzi hypothetical protein, conserved 0.0224 0.0172 0.0231
Echinococcus granulosus importin subunit beta 1 0.003 0.0012 0.0012
Echinococcus multilocularis allatostatin A receptor 0.0021 0.0004 0.0004
Loa Loa (eye worm) hypothetical protein 0.0085 0.0058 0.0058
Leishmania major DNA topoisomerase type IB small subunit 0.4613 0.3787 0.5103
Echinococcus granulosus histone acetyltransferase KAT2B 0.0587 0.0471 0.0471
Leishmania major DNA polymerase kappa, putative 0.0081 0.0054 0.0072
Brugia malayi bHLH-PAS transcription factor 0.022 0.0168 0.0168
Trichomonas vaginalis ferritin, putative 0.0035 0.0016 0.0325
Mycobacterium ulcerans hypothetical protein 0.0026 0.0009 0.0177
Schistosoma mansoni tsg101-related 0.0058 0.0035 0.0035
Brugia malayi jmjC domain containing protein 0.0043 0.0022 0.0022
Mycobacterium tuberculosis Bacterioferritin BfrB 0.0035 0.0016 0.0338
Entamoeba histolytica phosphatidylinositol3-kinaseTor2, putative 0.0048 0.0027 0.0527
Echinococcus granulosus caspase 3 apoptosis cysteine peptidase 0.024 0.0185 0.0185
Schistosoma mansoni histamine h1 receptor 0.0021 0.0004 0.0004
Mycobacterium tuberculosis Probable cytochrome P450 128 Cyp128 0.0019 0.0003 0.0049
Mycobacterium leprae PROBABLE SHORT CHAIN ALCOHOL DEHYDROGENASE/REDUCTASE 0.0023 0.0006 0.0132
Trypanosoma cruzi Lanosterol 14-alpha demethylase 0.0019 0.0003 0.0003
Entamoeba histolytica hypothetical protein, conserved 0.0023 0.0006 0.0093
Trypanosoma brucei DNA polymerase kappa, putative 0.0101 0.0071 0.0095
Leishmania major target of rapamycin kinase (TOR) kinase 3 0.0038 0.0019 0.0025
Trichomonas vaginalis CAMK family protein kinase 0.0195 0.0148 0.3102
Trypanosoma brucei beta-D-hydroxybutyrate dehydrogenase 0.0023 0.0006 0.0008
Plasmodium vivax flap endonuclease 1, putative 0.0027 0.001 0.0009
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.0592 0.0475 1
Echinococcus multilocularis rhodopsin orphan GPCR 0.0021 0.0004 0.0004
Schistosoma mansoni hepatocyte nuclear factor 4-alpha (hnf-4-alpha) 0.0085 0.0058 0.0058
Schistosoma mansoni alpha-glucosidase 0.0266 0.0206 0.0206
Trichomonas vaginalis alpha-glucosidase, putative 0.0031 0.0013 0.0266
Schistosoma mansoni ecdysone-induced protein 78c (dr-78) 0.0096 0.0066 0.0066
Leishmania major pteridine reductase 1 0.0023 0.0006 0.0008
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.0181 0.0136 0.0136
Trichomonas vaginalis inositol monophosphatase, putative 0.0117 0.0083 0.1745
Loa Loa (eye worm) hypothetical protein 0.0018 0.0002 0.0002
Loa Loa (eye worm) hypothetical protein 0.0181 0.0136 0.0136
Trypanosoma cruzi PAB1-binding protein , putative 0.0131 0.0095 0.0127
Loa Loa (eye worm) CXXC zinc finger family protein 0.0058 0.0035 0.0035
Schistosoma mansoni opsin-like receptor 0.0021 0.0004 0.0004
Mycobacterium ulcerans (3R)-hydroxyacyl-ACP dehydratase subunit HadA 0.0032 0.0014 0.0286
Mycobacterium ulcerans cytochrome P450 144A4 Cyp144A4 0.0019 0.0003 0.0049
Brugia malayi regulator of G-protein signaling rgs-7 0.0021 0.0004 0.0004
Echinococcus multilocularis neuropeptide s receptor 0.0576 0.0462 0.0462
Trypanosoma brucei MATE efflux family protein, putative 0.0069 0.0044 0.0058
Loa Loa (eye worm) jmjC domain-containing protein 0.0043 0.0022 0.0022
Trypanosoma brucei tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0068 0.0043 0.0058
Mycobacterium tuberculosis Probable cytochrome P450 141 Cyp141 0.0019 0.0003 0.0049
Trypanosoma cruzi mitogen activated protein kinase 2, putative 0.0051 0.0029 0.0039
Treponema pallidum DNA gyrase, subunit B (gyrB) 0.0074 0.0049 0.1012
Brugia malayi Cathepsin L-like precursor 0.0018 0.0002 0.0002
Leishmania major mitogen activated protein kinase 4, putative;with=GeneDB:LmxM19.1440 0.0051 0.0029 0.0039
Echinococcus multilocularis polycomb protein SCMH1 0.0047 0.0026 0.0026
Loa Loa (eye worm) latrophilin receptor protein 2 0.0019 0.0003 0.0003
Schistosoma mansoni ap endonuclease 0.0023 0.0006 0.0006
Brugia malayi isocitrate dehydrogenase 0.0097 0.0067 0.0067
Trypanosoma brucei DNA polymerase kappa, putative 0.005 0.0029 0.0038
Echinococcus multilocularis rhodopsin orphan GPCR 0.0021 0.0004 0.0004
Loa Loa (eye worm) oxidoreductase 0.0023 0.0006 0.0006
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.0298 0.0233 0.0233
Plasmodium vivax hypothetical protein, conserved 0.0029 0.0011 0.0011
Schistosoma mansoni ferritin light chain 0.0035 0.0016 0.0016
Trypanosoma brucei DNA polymerase kappa, putative 0.0058 0.0035 0.0047
Brugia malayi Muscle positioning protein 4 0.0018 0.0002 0.0002
Echinococcus granulosus Regulator of G protein signaling 20 0.0021 0.0004 0.0004
Mycobacterium ulcerans short-chain dehydrogenase 0.0023 0.0006 0.0132
Trypanosoma brucei Phosphatidylinositol 3-kinase tor1 0.0048 0.0027 0.0036
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0069 0.0044 0.0058
Leishmania major hypothetical protein, conserved 0.0224 0.0172 0.0231
Plasmodium vivax vivapain-2 0.0018 0.0002 0.0002
Trypanosoma brucei DNA polymerase kappa, putative 0.0101 0.0071 0.0095
Echinococcus multilocularis Alpha N acetylgalactosaminidase 0.021 0.016 0.016
Entamoeba histolytica DNA topoisomerase III, putative 0.0134 0.0098 0.202
Schistosoma mansoni hypothetical protein 0.0059 0.0036 0.0036
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0046 0.0025 0.0034
Echinococcus granulosus suppression of tumorigenicity 18 protein 0.0053 0.0031 0.0031
Loa Loa (eye worm) neuropeptide F receptor 0.0021 0.0004 0.0004
Loa Loa (eye worm) hypothetical protein 0.0072 0.0047 0.0047
Brugia malayi Glycosyl hydrolases family 31 protein 0.0084 0.0057 0.0057
Echinococcus granulosus inositol monophosphatase 1 0.0117 0.0083 0.0083
Trichomonas vaginalis short-chain dehydrogenase, putative 0.0023 0.0006 0.0127
Wolbachia endosymbiont of Brugia malayi dihydrolipoamide dehydrogenase E3 component 0.0046 0.0025 0.1067
Brugia malayi Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain containing protein 0.0034 0.0015 0.0015
Schistosoma mansoni tsg101-related 0.0058 0.0035 0.0035
Entamoeba histolytica deoxycytidyl transferase, putative 0.0074 0.0048 0.0976
Mycobacterium ulcerans carveol-like dehydrogenase 0.0023 0.0006 0.0132
Toxoplasma gondii Alpha-galactosidase 0.003 0.0012 0.0011
Loa Loa (eye worm) RGS-3 protein 0.0021 0.0004 0.0004
Trichomonas vaginalis CAMK family protein kinase 0.0195 0.0148 0.3102
Brugia malayi heat shock protein 90 0.0095 0.0065 0.0065
Leishmania major DNA polymerase eta, putative 0.0075 0.0049 0.0066
Plasmodium falciparum phd finger protein, putative 0.0029 0.0011 0.0011
Schistosoma mansoni transcription factor LCR-F1 0.033 0.0259 0.0259
Echinococcus granulosus SAM and MBT domain containing protein 0.0047 0.0026 0.0026
Loa Loa (eye worm) endoplasmin 0.0095 0.0065 0.0065
Leishmania major heat shock protein 83-1 0.0095 0.0065 0.0087
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0051 0.0029 0.0039
Trypanosoma cruzi PAB1-binding protein , putative 0.0131 0.0095 0.0127
Brugia malayi aryl hydrocarbon receptor AHR-1 0.0018 0.0002 0.0002
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0048 0.0027 0.0027
Trypanosoma cruzi hypothetical protein, conserved 0.0023 0.0006 0.0008
Schistosoma mansoni inositol monophosphatase 0.0117 0.0083 0.0083
Schistosoma mansoni hypothetical protein 0.0041 0.0021 0.0021
Onchocerca volvulus Uncharacterized family 31 glucosidase KIAA1161 homolog 0.0031 0.0013 0.019
Trypanosoma brucei heat shock protein, putative 0.0095 0.0065 0.0087
Leishmania major alpha glucosidase II subunit, putative 0.0084 0.0057 0.0076
Toxoplasma gondii exonuclease III APE 0.0023 0.0006 0.0006
Trichomonas vaginalis short-chain dehydrogenase, putative 0.0023 0.0006 0.0127
Plasmodium falciparum importin beta, putative 0.003 0.0012 0.0012
Leishmania major short chain dehydrogenase, putative 0.0023 0.0006 0.0008
Trichomonas vaginalis glucosylceramidase, putative 0.0192 0.0145 0.3051
Schistosoma mansoni amine GPCR 0.0021 0.0004 0.0004
Echinococcus multilocularis cathepsin l cysteine peptidase 0.0018 0.0002 0.0002
Loa Loa (eye worm) MH2 domain-containing protein 0.0019 0.0003 0.0003
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0019 0.0003 0.0003
Trypanosoma cruzi cytochrome P450, putative 0.0046 0.0025 0.0033
Plasmodium vivax heat shock protein 86, putative 0.0095 0.0065 0.0065
Loa Loa (eye worm) hypothetical protein 0.0023 0.0006 0.0006
Schistosoma mansoni axis inhibition protein axin 0.0021 0.0004 0.0004
Schistosoma mansoni heat shock protein 0.0053 0.0031 0.0031
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0023 0.0006 0.0006
Mycobacterium tuberculosis Fatty-acid-AMP ligase FadD30 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) 0.0021 0.0005 0.0098
Brugia malayi GTP-binding nuclear protein RAN/TC4 0.0022 0.0006 0.0006
Loa Loa (eye worm) RNA binding protein 0.0129 0.0093 0.0093
Schistosoma mansoni aryl hydrocarbon receptor 0.0305 0.0238 0.0238
Trypanosoma cruzi cysteine peptidase, clan CA, family C1, cathepsin L-like, putative 0.0063 0.0039 0.0052
Trypanosoma brucei phosphatidylinositol 4-kinase, putative 0.0048 0.0027 0.0036
Chlamydia trachomatis dihydrolipoyl dehydrogenase 0.0046 0.0025 0.0894
Leishmania major short chain dehydrogenase-like protein 0.0023 0.0006 0.0008
Schistosoma mansoni ferritin 0.0035 0.0016 0.0016
Echinococcus multilocularis g protein coupled receptor 0.0021 0.0004 0.0004
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.0181 0.0136 0.0136
Brugia malayi hypothetical protein 0.007 0.0045 0.0045
Loa Loa (eye worm) hypothetical protein 0.0021 0.0004 0.0004
Schistosoma mansoni steroid dehydrogenase 0.0023 0.0006 0.0006
Loa Loa (eye worm) hypothetical protein 0.0027 0.0009 0.0009
Echinococcus granulosus thyrotropin releasing hormone receptor 0.0021 0.0004 0.0004
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0069 0.0044 0.0058
Toxoplasma gondii HEAT repeat-containing protein 0.003 0.0012 0.0012
Brugia malayi Serotonin receptor 0.0021 0.0004 0.0004
Entamoeba histolytica acyl-CoA synthetase, putative 0.0029 0.0011 0.0185
Echinococcus multilocularis transient receptor potential gamma protein 0.0194 0.0147 0.0147
Echinococcus multilocularis DNA topoisomerase 3 beta 1 0.0134 0.0098 0.0098
Wolbachia endosymbiont of Brugia malayi bacterioferritin/cytochrome b1 0.0035 0.0016 0.0658
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0084 0.0057 0.1181
Trichomonas vaginalis glucosylceramidase, putative 0.0192 0.0145 0.3051
Mycobacterium ulcerans ketoacyl reductase 0.0023 0.0006 0.0132
Mycobacterium tuberculosis Cytochrome P450 121 Cyp121 0.0019 0.0003 0.0049
Mycobacterium ulcerans bacterioferritin BfrB 0.0035 0.0016 0.0338
Echinococcus multilocularis regulator of G protein signaling 7 0.0038 0.0019 0.0019
Echinococcus granulosus mothers against decapentaplegic 5 0.0042 0.0022 0.0022
Loa Loa (eye worm) hypothetical protein 0.0016 0.0001 0.0001
Brugia malayi ABC transporter family protein 0.0017 0.0001 0.0001
Entamoeba histolytica glycosyl hydrolase, family 31 protein 0.0031 0.0013 0.0232
Mycobacterium tuberculosis Possible multi-functional enzyme with acyl-CoA-reductase activity AcrA1 0.0023 0.0006 0.0132
Onchocerca volvulus 0.0021 0.0004 0.004
Entamoeba histolytica Ran family GTPase 0.0022 0.0006 0.0075
Giardia lamblia Grp94/Hsp90 0.0083 0.0056 0.1166
Trichomonas vaginalis conserved hypothetical protein 0.0021 0.0004 0.008
Mycobacterium ulcerans monooxygenase 0.0027 0.0009 0.019
Onchocerca volvulus 0.0018 0.0002 0.0003
Toxoplasma gondii ImpB/MucB/SamB family protein 0.0075 0.0049 0.0049
Plasmodium vivax importin-beta 2, putative 0.003 0.0012 0.0012
Echinococcus multilocularis rhodopsin orphan GPCR 0.0021 0.0004 0.0004
Onchocerca volvulus 0.0023 0.0006 0.0078
Brugia malayi Retinol dehydrogenase 12 0.0023 0.0006 0.0006
Mycobacterium tuberculosis holo-[acyl-carrier protein] synthase AcpS (holo-ACP synthase) (CoA:APO-[ACP]pantetheinephosphotransferase) (CoA:APO-[acyl-carrie 0.0167 0.0125 0.2733
Plasmodium falciparum heat shock protein 90 0.0095 0.0065 0.0065
Mycobacterium tuberculosis Probable cytochrome P450 125 Cyp125 0.0019 0.0003 0.0049
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0091 0.0062 0.1298
Trichomonas vaginalis glucosylceramidase, putative 0.0278 0.0216 0.4537
Trypanosoma cruzi heat shock protein 90, putative 0.0095 0.0065 0.0087
Echinococcus granulosus mitogen activated protein kinase 3 0.0051 0.0029 0.0029
Echinococcus multilocularis heat shock protein 90 0.0095 0.0065 0.0065
Schistosoma mansoni retinal dehydrogenase 0.0023 0.0006 0.0006
Echinococcus granulosus Niemann Pick C1 protein 0.0096 0.0066 0.0066
Brugia malayi hypothetical protein 0.0018 0.0002 0.0002
Toxoplasma gondii 4'-phosphopantetheinyl transferase superfamily protein 0.0167 0.0125 0.0125
Schistosoma mansoni ancient conserved domain protein 2 (cyclin m2) 0.0021 0.0004 0.0004
Giardia lamblia Short-chain dehydrogenase, putative 0.0023 0.0006 0.0127
Echinococcus granulosus sterol regulatory element binding protein 0.0041 0.0021 0.0021
Onchocerca volvulus 0.0018 0.0002 0.0003
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0091 0.0062 0.1298
Loa Loa (eye worm) hypothetical protein 0.0027 0.0009 0.0009
Trypanosoma brucei metacaspase 0.0091 0.0062 0.0083
Loa Loa (eye worm) hypothetical protein 0.014 0.0103 0.0103
Trichomonas vaginalis CAMK family protein kinase 0.0195 0.0148 0.3102
Trichomonas vaginalis PIKK family atypical protein kinase 0.0048 0.0027 0.056
Echinococcus granulosus ecdysone induced protein 78C 0.0181 0.0136 0.0136
Trichomonas vaginalis adenylate cyclase, putative 0.0085 0.0057 0.1195
Brugia malayi Nuclear hormone receptor family member nhr-41 0.0181 0.0136 0.0136
Leishmania major acetoin dehydrogenase e3 component-like protein 0.0046 0.0025 0.0034
Brugia malayi maoC like domain containing protein 0.0081 0.0054 0.0054
Schistosoma mansoni opsin-like receptor 0.0021 0.0004 0.0004
Trypanosoma cruzi DNA polymerase kappa, putative 0.0101 0.0071 0.0095
Trypanosoma brucei heat shock protein, putative 0.0095 0.0065 0.0087
Echinococcus multilocularis Dehydrogenase:reductase SDR family 0.0023 0.0006 0.0006
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD7 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0029 0.0011 0.0228
Schistosoma mansoni short chain dehydrogenase 0.0023 0.0006 0.0006
Echinococcus multilocularis Aryl hydrocarbon receptor nuclear 0.0085 0.0057 0.0057
Toxoplasma gondii oxidoreductase, short chain dehydrogenase/reductase family protein 0.0023 0.0006 0.0006
Onchocerca volvulus 0.0018 0.0002 0.0004
Brugia malayi polk-prov protein 0.005 0.0029 0.0029
Trypanosoma cruzi PAS-domain containing phosphoglycerate kinase, putative 0.0085 0.0057 0.0076
Mycobacterium ulcerans ketoacyl reductase 0.0023 0.0006 0.0132
Trypanosoma cruzi major cysteine proteinase, putative 0.0054 0.0032 0.0042
Leishmania major ATP-binding cassette protein subfamily G, member 6, putative 0.002 0.0004 0.0004
Loa Loa (eye worm) MH2 domain-containing protein 0.0042 0.0022 0.0022
Leishmania major heat shock protein, putative 0.0053 0.0031 0.0041
Brugia malayi Cytochrome P450 family protein 0.0046 0.0025 0.0025
Brugia malayi hypothetical protein 0.0096 0.0066 0.0066
Echinococcus multilocularis lysine specific demethylase 5A 0.016 0.0119 0.0119
Trichomonas vaginalis estradiol 17 beta-dehydrogenase, putative 0.0023 0.0006 0.0127
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0189 0.0143 0.3122
Loa Loa (eye worm) pax transcription factor protein 2 0.0729 0.0588 0.0587
Onchocerca volvulus 0.0298 0.0233 0.3942
Echinococcus granulosus 3 ketodihydrosphingosine reductase 0.0023 0.0006 0.0006
Leishmania major PAS-domain containing phosphoglycerate kinase, putative 0.0085 0.0057 0.0076
Onchocerca volvulus 0.0023 0.0006 0.0078
Mycobacterium ulcerans dihydrolipoamide dehydrogenase 0.0046 0.0025 0.0549
Brugia malayi MH1 domain containing protein 0.0042 0.0022 0.0022
Echinococcus granulosus zinc finger protein 0.0018 0.0002 0.0002
Mycobacterium ulcerans DNA topoisomerase I 0.0257 0.0199 0.4355
Chlamydia trachomatis two component regulatory system sensor histidine kinase 0.0101 0.007 0.2844
Brugia malayi hypothetical protein 0.0023 0.0006 0.0006
Brugia malayi Nuclear hormone receptor E75 0.0085 0.0058 0.0058
Trichomonas vaginalis short-chain dehydrogenase, putative 0.0023 0.0006 0.0127
Echinococcus multilocularis dna polymerase eta 0.0127 0.0092 0.0092
Brugia malayi hypothetical protein 0.0027 0.0009 0.0009
Onchocerca volvulus 0.0027 0.0009 0.0123
Plasmodium falciparum histone acetyltransferase GCN5 0.0163 0.0121 0.0121
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0023 0.0006 0.0006
Schistosoma mansoni multidrug resistance protein 0.0069 0.0044 0.0044
Echinococcus multilocularis caspase 0.024 0.0185 0.0185
Trypanosoma brucei glucosidase, putative 0.0084 0.0057 0.0076
Trypanosoma brucei trypanothione reductase 0.0134 0.0098 0.0131
Loa Loa (eye worm) short chain dehydrogenase/reductase family oxidoreductase 0.0061 0.0038 0.0037
Echinococcus granulosus nuclear receptor subfamily 1 group D 0.0096 0.0066 0.0066
Schistosoma mansoni hypothetical protein 0.0019 0.0003 0.0003
Echinococcus multilocularis Pleckstrin G protein, interacting region 0.0018 0.0002 0.0002
Leishmania major heat shock protein 83-1 0.0095 0.0065 0.0087
Mycobacterium tuberculosis Probable isocitrate dehydrogenase [NADP] Icd1 (oxalosuccinate decarboxylase) (IDH) (NADP+-specific ICDH) (IDP) 0.0097 0.0067 0.146
Leishmania major cathepsin L-like protease 0.0018 0.0002 0.0002
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0085 0.0058 0.0058
Loa Loa (eye worm) Smad1 0.0042 0.0022 0.0022
Trichomonas vaginalis maltase-glucoamylase, putative 0.0031 0.0013 0.0266
Mycobacterium ulcerans short chain dehydrogenase 0.0023 0.0006 0.0132
Brugia malayi hypothetical protein 0.0027 0.0009 0.0009
Echinococcus granulosus PHD finger protein rhinoceros 0.0029 0.0011 0.0011
Leishmania major DNA topoisomerase 1A 0.0257 0.0199 0.0268
Loa Loa (eye worm) hypothetical protein 0.0021 0.0004 0.0004
Trypanosoma cruzi hypothetical protein, conserved 0.0023 0.0006 0.0008
Loa Loa (eye worm) oxidoreductase 0.0023 0.0006 0.0006
Trypanosoma brucei heat shock protein, putative 0.0095 0.0065 0.0087
Echinococcus granulosus mitogen activated protein kinase 0.0051 0.0029 0.0029
Onchocerca volvulus 0.0023 0.0006 0.0078
Leishmania major 3-keto-dihydrosphingosine reductase 0.0023 0.0006 0.0008
Onchocerca volvulus 0.0018 0.0002 0.0004
Brugia malayi Cell death protein 3 precursor 0.0175 0.0132 0.0132
Echinococcus multilocularis lamin 0.0056 0.0033 0.0033
Brugia malayi dehydrogenases, short chain protein 9 0.0023 0.0006 0.0006
Leishmania major DNA polymerase eta, putative 0.0127 0.0092 0.0123
Schistosoma mansoni regulator of G protein signaling 0.0038 0.0019 0.0019
Loa Loa (eye worm) hypothetical protein 0.0082 0.0055 0.0054
Plasmodium vivax dihydrolipoyl dehydrogenase, mitochondrial, putative 0.0046 0.0025 0.0025
Giardia lamblia Flap structure-specific endonuclease 0.0027 0.001 0.0198
Brugia malayi oxidoreductase 0.0023 0.0006 0.0006
Schistosoma mansoni protein phosphatase 2C 0.0043 0.0022 0.0022
Echinococcus granulosus heat shock protein 75 kDa mitochondrial 0.0053 0.0031 0.0031
Trichomonas vaginalis PIKK family atypical protein kinase 0.0026 0.0009 0.0175
Trypanosoma cruzi ABC transporter, putative 0.002 0.0004 0.0004
Schistosoma mansoni carbonyl reductase 0.0023 0.0006 0.0006
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.0181 0.0136 0.0136
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0051 0.0029 0.0039
Trypanosoma brucei glycosyl hydrolase-like protein 0.0031 0.0013 0.0017
Loa Loa (eye worm) hypothetical protein 0.0023 0.0006 0.0006
Leishmania major 4-coumarate:coa ligase-like protein 0.0029 0.0011 0.0014
Plasmodium vivax heat shock protein, putative 0.0226 0.0173 0.0173
Brugia malayi MAP kinase sur-1 0.0051 0.0029 0.0029
Schistosoma mansoni ATP-binding cassette sub-family g2 (white protein) (abcg2) 0.002 0.0004 0.0004
Trypanosoma cruzi short-chain dehydrogenase, putative 0.0023 0.0006 0.0008
Plasmodium vivax ABC transporter G family member 2, putative 0.002 0.0004 0.0003
Trichomonas vaginalis conserved hypothetical protein 0.0021 0.0004 0.008
Onchocerca volvulus Globin homolog 0.0027 0.0009 0.0123
Trypanosoma cruzi JmjC domain, hydroxylase, putative 0.0043 0.0022 0.003
Schistosoma mansoni hypothetical protein 0.033 0.0259 0.0259
Echinococcus granulosus terminal deoxycytidyl transferase rev1 0.0074 0.0048 0.0048
Echinococcus granulosus lysine specific demethylase 5A 0.0164 0.0122 0.0122
Mycobacterium ulcerans hypothetical protein 0.0023 0.0006 0.0126
Entamoeba histolytica glycosyl hydrolase, family 31 protein 0.0084 0.0057 0.1151
Schistosoma mansoni cellular tumor antigen P53 0.0053 0.0031 0.0031
Echinococcus granulosus phosphatidylinositol 3 and 4 kinase 0.0016 0.0001 0.0001
Onchocerca volvulus 0.0027 0.0009 0.0123
Brugia malayi putative neuropeptide receptor 0.0021 0.0004 0.0004
Loa Loa (eye worm) hypothetical protein 0.0096 0.0066 0.0066
Trypanosoma cruzi DNA polymerase kappa, putative 0.0101 0.0071 0.0095
Trichomonas vaginalis PIKK family atypical protein kinase 0.0016 0.0001 0.0004
Trichomonas vaginalis CMGC family protein kinase 0.0051 0.0029 0.0611
Brugia malayi G protein-coupled receptor 0.0021 0.0004 0.0004
Trichomonas vaginalis PIKK family atypical protein kinase 0.0016 0.0001 0.0004
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0117 0.0083 0.1745
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0021 0.0004 0.0004
Onchocerca volvulus 0.0021 0.0004 0.004
Schistosoma mansoni histamine-responsive GPCR (AAF21638) 0.0021 0.0004 0.0004
Entamoeba histolytica serine/threonine protein kinase, putative 0.0195 0.0148 0.3078
Loa Loa (eye worm) hypothetical protein 0.0085 0.0058 0.0058
Brugia malayi hypothetical protein 0.0021 0.0004 0.0004
Brugia malayi GnHR receptor homolog 0.0021 0.0004 0.0004
Schistosoma mansoni opsin-like receptor 0.0021 0.0004 0.0004
Loa Loa (eye worm) hypothetical protein 0.0021 0.0004 0.0004
Echinococcus multilocularis FKBP12 rapamycin complex associated protein 0.0048 0.0027 0.0027
Mycobacterium ulcerans bacterioferritin BfrA 0.0035 0.0016 0.0338
Loa Loa (eye worm) hypothetical protein 0.0021 0.0004 0.0004
Brugia malayi Dehydrogenases, short chain protein 30 0.0023 0.0006 0.0006
Toxoplasma gondii target of rapamycin (TOR), putative 0.0036 0.0017 0.0016
Trypanosoma brucei short-chain dehydrogenase, putative 0.0023 0.0006 0.0008
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 8 0.0045 0.0024 0.0024
Plasmodium falciparum dihydrolipoyl dehydrogenase, apicoplast 0.0046 0.0025 0.0025
Schistosoma mansoni z-protein (S1r protein) 0.0038 0.0019 0.0019
Schistosoma mansoni nuclear hormone receptor 0.0181 0.0136 0.0136
Trypanosoma brucei GTP-binding nuclear protein rtb2, putative 0.0022 0.0006 0.0007
Brugia malayi hypothetical protein 0.0021 0.0004 0.0004
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0048 0.0027 0.0027
Brugia malayi aryl hydrocarbon receptor nuclear translocator protein, putative 0.0018 0.0002 0.0002
Echinococcus granulosus g protein coupled receptor 0.0021 0.0004 0.0004
Loa Loa (eye worm) hypothetical protein 0.0026 0.0009 0.0009
Mycobacterium tuberculosis Decaprenylphosphoryl-D-2-keto erythro pentose reductase 0.0023 0.0006 0.0132
Onchocerca volvulus 0.0021 0.0004 0.004
Echinococcus granulosus Protein patched homolog 1 0.0041 0.0021 0.0021
Echinococcus granulosus mixed lineage leukemia protein mll 0.0017 0.0001 0.0001
Loa Loa (eye worm) steroid hormone receptor 0.0181 0.0136 0.0136
Schistosoma mansoni ubiquitin-specific peptidase 8 (C19 family) 0.0045 0.0024 0.0024
Trichomonas vaginalis conserved hypothetical protein 0.0021 0.0004 0.008
Schistosoma mansoni survival motor neuron protein 0.0298 0.0233 0.0233
Echinococcus multilocularis carbonyl reductase 1 0.0023 0.0006 0.0006
Entamoeba histolytica estradiol 17-beta-dehydrogenase, putative 0.0023 0.0006 0.0093
Trypanosoma cruzi hypothetical protein, conserved 0.0224 0.0172 0.0231
Loa Loa (eye worm) hypothetical protein 0.0018 0.0002 0.0002
Loa Loa (eye worm) hypothetical protein 0.0019 0.0003 0.0003
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0021 0.0004 0.0004
Schistosoma mansoni nuclear hormone receptor 0.0085 0.0058 0.0058
Schistosoma mansoni smad1 5 8 and 0.0042 0.0022 0.0022
Schistosoma mansoni intermediate filament proteins 0.0056 0.0033 0.0033
Echinococcus multilocularis neuropeptide receptor 0.0021 0.0004 0.0004
Entamoeba histolytica tumor susceptibility gene 101 protein, putative 0.0047 0.0026 0.0511
Brugia malayi PXA domain containing protein 0.0021 0.0004 0.0004
Echinococcus granulosus Jumonji AT rich interactive domain 1B 0.0046 0.0025 0.0025
Echinococcus multilocularis dnaJ subfamily B 0.0825 0.0667 0.0667
Echinococcus granulosus caspase 2 0.0175 0.0132 0.0132
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0048 0.0027 0.0027
Loa Loa (eye worm) oxidoreductase 0.0023 0.0006 0.0006
Echinococcus granulosus tachykinin peptides receptor 99D 0.0021 0.0004 0.0004
Trichomonas vaginalis guanylate cyclase, putative 0.0085 0.0057 0.1195
Loa Loa (eye worm) hypothetical protein 0.0085 0.0058 0.0058
Echinococcus multilocularis dihydrolipoamide dehydrogenase 0.0046 0.0025 0.0025
Echinococcus multilocularis regulator of G protein signaling 7 0.0038 0.0019 0.0019
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0018 0.0002 0.0035
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0592 0.0475 1
Mycobacterium leprae Probable oxidoreductase 0.0023 0.0006 0.0132
Schistosoma mansoni carbonyl reductase 0.0023 0.0006 0.0006
Chlamydia trachomatis holo [acyl-carrier protein] synthase 0.0167 0.0125 0.5224
Mycobacterium ulcerans short chain dehydrogenase 0.0023 0.0006 0.0132
Trichomonas vaginalis conserved hypothetical protein 0.0045 0.0024 0.0497
Plasmodium falciparum cysteine proteinase falcipain 2b 0.0018 0.0002 0.0002
Schistosoma mansoni alpha-galactosidase/alpha-n-acetylgalactosaminidase 0.014 0.0103 0.0103
Onchocerca volvulus Protein cycle homolog 0.0018 0.0002 0.0003
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 8 0.0045 0.0024 0.0024
Schistosoma mansoni hypothetical protein 0.004 0.002 0.002
Onchocerca volvulus 0.0023 0.0006 0.0078
Trypanosoma brucei heat shock protein 84, putative 0.0053 0.0031 0.0041
Mycobacterium tuberculosis Probable bacterioferritin BfrA 0.0035 0.0016 0.0338
Schistosoma mansoni NADP-specific isocitrate dehydrogenase 0.0097 0.0067 0.0067
Mycobacterium tuberculosis Probable short-chain type dehydrogenase/reductase 0.0023 0.0006 0.0132
Treponema pallidum heat shock protein 90 0.0083 0.0056 0.1166
Brugia malayi mbt repeat family protein 0.0047 0.0026 0.0026
Brugia malayi Hsp90 protein 0.0053 0.0031 0.0031
Trypanosoma cruzi Phosphatidylinositol 3-kinase tor1 0.0048 0.0027 0.0036
Trichomonas vaginalis conserved hypothetical protein 0.0091 0.0062 0.1298
Schistosoma mansoni ran 0.0022 0.0006 0.0006
Onchocerca volvulus 0.0021 0.0004 0.004
Brugia malayi MH1 domain containing protein 0.0042 0.0022 0.0022
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.033 0.0259 0.0259
Echinococcus multilocularis mixed lineage leukemia protein mll 0.0017 0.0001 0.0001
Brugia malayi conserved hypotetical protein 0.0085 0.0058 0.0058
Trypanosoma cruzi mitochondrial DNA topoisomerase II, putative 0.0074 0.0049 0.0065
Mycobacterium ulcerans dehydrogenase/decarboxylase protein 0.0023 0.0006 0.0132
Echinococcus multilocularis Peptidase C19, ubiquitin carboxyl terminal hydrolase 2 0.0045 0.0024 0.0024
Echinococcus multilocularis muscleblind protein 1 0.0619 0.0498 0.0498
Onchocerca volvulus Cathepsin L homolog 0.0018 0.0002 0.0003
Brugia malayi AMP-binding enzyme family protein 0.0029 0.0011 0.0011
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0592 0.0475 1
Mycobacterium tuberculosis Probable cytochrome P450 144 Cyp144 0.0019 0.0003 0.0049
Schistosoma mansoni microtubule-associated protein tau 0.2077 0.1698 0.1698
Plasmodium vivax DNA topoisomerase II, putative 0.0074 0.0049 0.0048
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0017 0.0001 0.0001
Leishmania major cytochrome p450-like protein 0.0019 0.0003 0.0003
Echinococcus multilocularis transcription factor Dp 1 0.0039 0.002 0.002
Onchocerca volvulus 0.0021 0.0004 0.004
Brugia malayi nuclear receptor RXR 0.0096 0.0066 0.0066
Brugia malayi DNA topoisomerase III beta-1 0.0134 0.0098 0.0098
Schistosoma mansoni sex comb on midleg homolog 0.0047 0.0026 0.0026
Brugia malayi Dopamine receptor protein 1, putative (partial) 0.0021 0.0004 0.0004
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0048 0.0027 0.0027
Brugia malayi exodeoxyribonuclease III family protein 0.0023 0.0006 0.0006
Trypanosoma brucei flap endonuclease-1 (FEN-1), putative 0.0027 0.001 0.0013
Echinococcus granulosus GTP binding nuclear protein Ran 0.0022 0.0006 0.0006
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.0023 0.0006 0.0006
Loa Loa (eye worm) hypothetical protein 0.0383 0.0303 0.0302
Schistosoma mansoni jumonji domain containing protein 0.0201 0.0153 0.0153
Toxoplasma gondii NADPH-glutathione reductase 0.0046 0.0025 0.0025
Toxoplasma gondii oxidoreductase, putative 0.0023 0.0006 0.0006
Loa Loa (eye worm) hypothetical protein 0.1461 0.1191 0.1191
Echinococcus multilocularis rhodopsin orphan GPCR 0.0021 0.0004 0.0004
Trichomonas vaginalis alpha-glucosidase, putative 0.0031 0.0013 0.0266
Schistosoma mansoni thyrotropin-releasing hormone receptor 0.0021 0.0004 0.0004
Loa Loa (eye worm) MH1 domain-containing protein 0.0042 0.0022 0.0022
Trichomonas vaginalis PIKK family atypical protein kinase 0.0016 0.0001 0.0004
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0046 0.0025 0.0034
Loa Loa (eye worm) hypothetical protein 0.0021 0.0004 0.0004
Loa Loa (eye worm) hypothetical protein 0.0021 0.0004 0.0004
Mycobacterium tuberculosis Probable short-chain type dehydrogenase/reductase 0.0023 0.0006 0.0132
Mycobacterium tuberculosis Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) 0.0023 0.0006 0.0121
Echinococcus multilocularis regulator of G protein signaling 0.0021 0.0004 0.0004
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0085 0.0058 0.0058
Leishmania major DNA topoisomerase III, putative 0.0134 0.0098 0.0131
Trypanosoma brucei membrane transporter protein, putative 0.0069 0.0044 0.0058
Mycobacterium ulcerans DNA gyrase subunit B 0.0074 0.0049 0.1053
Brugia malayi nuclear receptor NHR-88 0.0085 0.0058 0.0058
Brugia malayi jmjC domain containing protein 0.0043 0.0022 0.0022
Trichomonas vaginalis prokaryotic DNA topoisomerase, putative 0.0076 0.005 0.1035
Trypanosoma brucei heat shock protein, putative 0.0095 0.0065 0.0087
Treponema pallidum bacterioferrin (TpF1) 0.0035 0.0016 0.0325
Loa Loa (eye worm) hypothetical protein 0.0018 0.0002 0.0002
Toxoplasma gondii isocitrate dehydrogenase 0.0097 0.0067 0.0067
Echinococcus granulosus snurportin 1 0.0324 0.0254 0.0254
Plasmodium falciparum glutathione reductase 0.0046 0.0025 0.0025
Leishmania major GTP-binding protein, putative 0.0022 0.0006 0.0007
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0117 0.0083 0.0112
Trichomonas vaginalis alpha-glucosidase, putative 0.0084 0.0057 0.1181
Echinococcus granulosus cathepsin l cysteine peptidase 0.0018 0.0002 0.0002
Schistosoma mansoni hypothetical protein 0.0159 0.0118 0.0118
Brugia malayi hypothetical protein 0.0027 0.0009 0.0009
Treponema pallidum fructose-bisphosphate aldolase 0.0592 0.0475 1
Toxoplasma gondii histone lysine demethylase JMJC1/KDM5D/JARID1D 0.0043 0.0022 0.0022
Entamoeba histolytica tyrosyl-DNA phosphodiesterase, putative 0.0068 0.0043 0.087
Trichomonas vaginalis steroid dehydrogenase, putative 0.0023 0.0006 0.0127
Loa Loa (eye worm) hypothetical protein 0.0021 0.0004 0.0004
Leishmania major 4-coumarate:coa ligase-like protein 0.0029 0.0011 0.0014
Echinococcus multilocularis retinol dehydrogenase 11 0.0023 0.0006 0.0006
Echinococcus granulosus Nuclear hormone receptor HR96 0.0085 0.0058 0.0058
Schistosoma mansoni myelin transcription factor 1 myt1 0.0053 0.0031 0.0031
Giardia lamblia Kinase, CMGC MAPK 0.0051 0.0029 0.0611
Trichomonas vaginalis importin beta-1, putative 0.0025 0.0008 0.0149
Schistosoma mansoni importin beta-1 0.003 0.0012 0.0012
Trichomonas vaginalis conserved hypothetical protein 0.0085 0.0057 0.1195
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0025 0.0008 0.0149
Schistosoma mansoni Smad4 0.0019 0.0003 0.0003
Echinococcus granulosus hypothetical protein 0.0762 0.0615 0.0615
Echinococcus multilocularis sterol regulatory element binding protein 0.0041 0.0021 0.0021
Brugia malayi Dehydrogenases, short chain protein 2 0.0023 0.0006 0.0006
Plasmodium vivax holo-[acyl-carrier-protein] synthase, putative 0.0167 0.0125 0.0125
Trypanosoma cruzi hypothetical protein, conserved 0.0069 0.0044 0.0058
Echinococcus multilocularis caspase 3, apoptosis cysteine peptidase 0.024 0.0185 0.0185
Trypanosoma cruzi membrane transporter protein, putative 0.0069 0.0044 0.0058
Schistosoma mansoni endoplasmin 0.0095 0.0065 0.0065
Brugia malayi putative neuropeptide receptor NPR1 0.0021 0.0004 0.0004
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0046 0.0025 0.0034
Echinococcus granulosus kelch ECH associated protein 1 0.0094 0.0065 0.0065
Schistosoma mansoni alpha-1 adrenergic receptor 0.0021 0.0004 0.0004
Mycobacterium leprae Probable short-chain type dehydrogenase/reductase 0.0023 0.0006 0.0132
Mycobacterium tuberculosis Probable cytochrome P450 138 Cyp138 0.0019 0.0003 0.0049
Leishmania major heat shock protein 83-1 0.0095 0.0065 0.0087
Leishmania major phosphopantetheinyl transferase-like protein 0.0167 0.0125 0.0168
Loa Loa (eye worm) hypothetical protein 0.0021 0.0004 0.0004
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0018 0.0002 0.0035
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0181 0.0136 0.0136
Mycobacterium ulcerans dehydrogenase/reductase 0.0023 0.0006 0.0132
Loa Loa (eye worm) DR-78 0.0085 0.0058 0.0058
Mycobacterium ulcerans short-chain membrane-associated dehydrogenase 0.0023 0.0006 0.0132
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0021 0.0004 0.0004
Mycobacterium ulcerans transcriptional regulator 0.0032 0.0013 0.0284
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.006 0.0037 0.0037
Giardia lamblia Heat shock protein HSP 90-alpha 0.0095 0.0065 0.1363
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0592 0.0475 1
Loa Loa (eye worm) hypothetical protein 0.0021 0.0004 0.0004
Loa Loa (eye worm) hypothetical protein 0.0064 0.004 0.004
Onchocerca volvulus 0.0066 0.0042 0.0678
Loa Loa (eye worm) nuclear hormone receptor-like 1 0.0096 0.0066 0.0066
Schistosoma mansoni DNA topoisomerase type I 0.9025 0.7422 0.7422
Echinococcus granulosus g-protein coupled receptor 0.0021 0.0004 0.0004
Loa Loa (eye worm) MBCTL1 0.0053 0.0031 0.0031
Mycobacterium ulcerans oxidoreductase 0.0023 0.0006 0.0132
Onchocerca volvulus 0.0018 0.0002 0.0004
Echinococcus multilocularis heat shock protein 0.0095 0.0065 0.0065
Echinococcus granulosus jumonji domain containing protein 0.0041 0.0021 0.0021
Echinococcus granulosus DNA topoisomerase 3 beta 1 0.0134 0.0098 0.0098
Onchocerca volvulus 0.0021 0.0004 0.004
Trypanosoma cruzi beta-ketoacyl-ACP reductase 2, putative 0.0023 0.0006 0.0008
Loa Loa (eye worm) hypothetical protein 0.0081 0.0054 0.0054
Brugia malayi hypothetical protein 0.0085 0.0057 0.0057
Trypanosoma cruzi 3-keto-dihydrosphingosine reductase 0.0023 0.0006 0.0008
Trichomonas vaginalis PIKK family atypical protein kinase 0.0026 0.0009 0.0175
Brugia malayi Papain family cysteine protease containing protein 0.0018 0.0002 0.0002
Loa Loa (eye worm) hypothetical protein 0.0361 0.0285 0.0285
Entamoeba histolytica estradiol 17-beta-dehydrogenase, putative 0.0023 0.0006 0.0093
Mycobacterium ulcerans exodeoxyribonuclease III protein XthA 0.0023 0.0006 0.0121
Schistosoma mansoni cpg binding protein 0.0061 0.0038 0.0038
Mycobacterium ulcerans cytochrome P450 51B1 Cyp51B1 0.0019 0.0003 0.0049
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0018 0.0002 0.0035
Schistosoma mansoni niemann-pick C1 (NPC1) 0.0098 0.0068 0.0068
Loa Loa (eye worm) thioredoxin reductase 0.0134 0.0098 0.0097
Onchocerca volvulus 0.0085 0.0057 0.0939
Trichomonas vaginalis CAMK family protein kinase 0.0195 0.0148 0.3102
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.0181 0.0136 0.0136
Wolbachia endosymbiont of Brugia malayi Short-chain alcohol dehydrogenase family enzyme 0.0023 0.0006 0.0257
Echinococcus multilocularis GPCR, family 2 0.0019 0.0003 0.0003
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0046 0.0025 0.0034
Loa Loa (eye worm) oxidoreductase 0.0023 0.0006 0.0006
Brugia malayi Cathepsin L-like precursor 0.0018 0.0002 0.0002
Trypanosoma cruzi hypothetical protein, conserved 0.0069 0.0044 0.0058
Trypanosoma cruzi cysteine peptidase, putative 0.0069 0.0044 0.0058
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.0592 0.0475 1
Toxoplasma gondii flap structure-specific endonuclease 1, putative 0.0027 0.001 0.0009
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD2 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0029 0.0011 0.0228
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.0023 0.0006 0.0006
Brugia malayi jmjC domain containing protein 0.0043 0.0022 0.0022
Trypanosoma brucei DNA polymerase IV, putative 0.0101 0.0071 0.0095
Loa Loa (eye worm) hypothetical protein 0.0021 0.0004 0.0004
Leishmania major hypothetical protein, conserved 0.0023 0.0006 0.0008
Trypanosoma cruzi polo-like protein kinase, putative 0.0195 0.0148 0.0199
Loa Loa (eye worm) hypothetical protein 0.0021 0.0004 0.0004
Echinococcus granulosus DNA topoisomerase 2 alpha 0.0074 0.0049 0.0049
Loa Loa (eye worm) intermediate filament protein 0.0056 0.0033 0.0033
Leishmania major importin beta-1 subunit, putative 0.0025 0.0008 0.001
Echinococcus multilocularis segment polarity protein dishevelled 0.0018 0.0002 0.0002
Entamoeba histolytica hypothetical protein 0.0021 0.0004 0.0045
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0021 0.0004 0.0004
Brugia malayi Cytochrome P450 family protein 0.0019 0.0003 0.0003
Loa Loa (eye worm) hypothetical protein 0.0027 0.0009 0.0009
Schistosoma mansoni short chain dehydrogenase 0.0023 0.0006 0.0006
Loa Loa (eye worm) flap endonuclease-1 0.0027 0.001 0.001
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0091 0.0062 0.1298
Onchocerca volvulus Bile acid receptor homolog 0.0181 0.0136 0.2296
Echinococcus granulosus 7TM GPCR rhodopsin 0.0021 0.0004 0.0004
Toxoplasma gondii SWI2/SNF2-containing protein 0.0044 0.0023 0.0023
Trypanosoma cruzi NAD(P)-dependent oxidoreductase, putative 0.0023 0.0006 0.0008
Onchocerca volvulus 0.0021 0.0004 0.004
Schistosoma mansoni alpha-glucosidase 0.0266 0.0206 0.0206
Echinococcus granulosus neuropeptide s receptor 0.0576 0.0462 0.0462
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0029 0.0011 0.0228
Loa Loa (eye worm) globin family protein 0.0027 0.0009 0.0009
Echinococcus multilocularis ATP binding cassette sub family G 0.002 0.0004 0.0004
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0023 0.0006 0.0132
Echinococcus granulosus g protein coupled receptor 0.0021 0.0004 0.0004
Schistosoma mansoni sex comb on midleg homolog 0.0047 0.0026 0.0026
Loa Loa (eye worm) histone methyltransferase 0.002 0.0004 0.0004
Toxoplasma gondii oxidoreductase, short chain dehydrogenase/reductase family protein 0.0023 0.0006 0.0006
Echinococcus multilocularis expressed conserved protein 0.009 0.0062 0.0062
Schistosoma mansoni hypothetical protein 0.0068 0.0044 0.0044
Echinococcus granulosus geminin 0.1214 0.0988 0.0988
Plasmodium vivax steroid dehydrogenase, putative 0.0023 0.0006 0.0006
Brugia malayi AKH receptor 0.0021 0.0004 0.0004
Echinococcus multilocularis steroid dehydrogenase 0.0023 0.0006 0.0006
Echinococcus multilocularis muscleblind protein 0.0619 0.0498 0.0498
Onchocerca volvulus Alhambra homolog 0.0029 0.0011 0.0163
Trichomonas vaginalis PIKK family atypical protein kinase 0.0026 0.0009 0.0175
Loa Loa (eye worm) hypothetical protein 0.0021 0.0004 0.0004
Leishmania major hypothetical protein, conserved 0.0023 0.0006 0.0008
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0045 0.0024 0.0497
Schistosoma mansoni tyrosyl-DNA phosphodiesterase 0.0068 0.0043 0.0043
Echinococcus granulosus regulator of G protein signaling 7 0.0038 0.0019 0.0019
Trichomonas vaginalis glucosylceramidase, putative 0.0182 0.0137 0.2881
Schistosoma mansoni hypothetical protein 0.0019 0.0003 0.0003
Echinococcus multilocularis retinoic acid receptor rxr beta a retinoic acid receptor rxr alpha a retinoic acid receptor rxr alpha 0.0085 0.0058 0.0058
Schistosoma mansoni hypothetical protein 0.0324 0.0254 0.0254
Echinococcus multilocularis growth hormone secretagogue receptor type 1 0.0021 0.0004 0.0004
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0045 0.0024 0.0024
Echinococcus multilocularis thyrotropin releasing hormone receptor 0.0021 0.0004 0.0004
Echinococcus granulosus rhodopsin orphan GPCR 0.0021 0.0004 0.0004
Brugia malayi Serotonin/octopamine receptor family protein 7 0.0021 0.0004 0.0004
Schistosoma mansoni RAR-like nuclear receptor 0.0181 0.0136 0.0136
Echinococcus multilocularis mothers against decapentaplegic 5 0.0042 0.0022 0.0022
Mycobacterium tuberculosis Possible ketoacyl reductase 0.0023 0.0006 0.0132
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0181 0.0136 0.0136
Loa Loa (eye worm) nucleolar RNA-associated protein alpha 0.0324 0.0254 0.0254
Echinococcus granulosus beta-adrenergic receptor kinase 0.0022 0.0006 0.0006
Loa Loa (eye worm) abnormal chemotaxis protein 14 0.0041 0.0021 0.0021
Loa Loa (eye worm) inositol-1 0.0117 0.0083 0.0083
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.0023 0.0006 0.0006
Trypanosoma brucei short-chain dehydrogenase, putative 0.0023 0.0006 0.0008
Echinococcus granulosus nuclear factor of activated T cells 5 0.0079 0.0052 0.0052
Brugia malayi mucosa associated lymphoid tissue lymphoma translocation protein 1 0.0091 0.0062 0.0062
Brugia malayi Regulator of G protein signaling domain containing protein 0.0021 0.0004 0.0004
Trichomonas vaginalis alpha-glucosidase, putative 0.0084 0.0057 0.1181
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0023 0.0006 0.0132
Trypanosoma brucei unspecified product 0.0051 0.0029 0.0039
Plasmodium vivax metacaspase 1, putative 0.0091 0.0062 0.0062
Trichomonas vaginalis adenylate and guanylate cyclases, putative 0.0085 0.0057 0.1195
Brugia malayi SEA domain containing protein 0.0018 0.0002 0.0002
Trypanosoma cruzi DNA polymerase eta, putative 0.0127 0.0092 0.0123
Loa Loa (eye worm) nuclear receptor nhr-7B 0.0085 0.0058 0.0058
Giardia lamblia ABC transporter 0.002 0.0003 0.0064
Trypanosoma cruzi DNA polymerase kappa, putative 0.0101 0.0071 0.0095
Echinococcus multilocularis survival motor neuron protein 1 0.1461 0.1191 0.1191
Brugia malayi hypothetical protein 0.0085 0.0058 0.0058
Schistosoma mansoni regulator of G protein signaling 17 19 20 (rgs17 19 20) 0.0021 0.0004 0.0004
Trichomonas vaginalis alpha-glucosidase, putative 0.0084 0.0057 0.1181
Schistosoma mansoni hypothetical protein 0.004 0.002 0.002
Plasmodium falciparum JmjC domain-containing protein, putative 0.0043 0.0022 0.0022
Brugia malayi C2-HC type zinc finger protein C.e-MyT1 0.0053 0.0031 0.0031
Trypanosoma cruzi trypanothione reductase, putative 0.0134 0.0098 0.0131
Brugia malayi hypothetical protein 0.0096 0.0066 0.0066
Echinococcus multilocularis tumor protein p63 0.0363 0.0286 0.0286
Leishmania major protein kinase, putative 0.0094 0.0065 0.0087
Brugia malayi glutathione reductase 0.0134 0.0098 0.0098
Echinococcus multilocularis thyroid hormone receptor alpha 0.0181 0.0136 0.0136
Trypanosoma brucei DNA polymerase kappa, putative 0.0101 0.0071 0.0095
Echinococcus multilocularis neutral alpha glucosidase AB 0.0084 0.0057 0.0057
Loa Loa (eye worm) AGC/GRK/GRK protein kinase 0.0022 0.0006 0.0005
Trichomonas vaginalis alpha-glucosidase, putative 0.0031 0.0013 0.0266
Schistosoma mansoni steroid dehydrogenase 0.0023 0.0006 0.0006
Trypanosoma cruzi apurinic/apyrimidinic endonuclease 0.0023 0.0006 0.0007
Onchocerca volvulus 0.05 0.0399 0.6782
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0061 0.0038 0.0814
Brugia malayi Dopamine receptor protein 2 0.0021 0.0004 0.0004
Brugia malayi DNA gyrase/topoisomerase IV, A subunit family protein 0.0074 0.0049 0.0049
Mycobacterium ulcerans short chain dehydrogenase 0.0023 0.0006 0.0132
Echinococcus granulosus tumor protein p63 0.0363 0.0286 0.0286
Schistosoma mansoni caspase-7 (C14 family) 0.0175 0.0132 0.0132
Mycobacterium ulcerans short chain dehydrogenase 0.0023 0.0006 0.0132
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0031 0.0013 0.0266
Trypanosoma cruzi isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0097 0.0067 0.009
Echinococcus granulosus jun protein 0.0084 0.0056 0.0056
Brugia malayi PHD-finger family protein 0.0029 0.0011 0.0011
Trypanosoma cruzi short-chain dehydrogenase, putative 0.0023 0.0006 0.0008
Schistosoma mansoni short chain dehydrogenase 0.0023 0.0006 0.0006
Mycobacterium tuberculosis Probable 3-hydroxyacyl-thioester dehydratase HtdY 0.0081 0.0054 0.1173
Loa Loa (eye worm) hypothetical protein 0.0021 0.0004 0.0004
Treponema pallidum 4'-phosphopantetheinyl transferase 0.0167 0.0125 0.2626
Echinococcus multilocularis suppression of tumorigenicity 18 protein 0.0053 0.0031 0.0031
Loa Loa (eye worm) hypothetical protein 0.0194 0.0147 0.0147
Brugia malayi cytochrome P450 0.0019 0.0003 0.0003
Brugia malayi 3-hydroxyacyl-CoA dehydrogenase type II 0.0189 0.0143 0.0143
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0181 0.0136 0.0136
Plasmodium falciparum ataxin-2 like protein, putative 0.0131 0.0095 0.0095
Brugia malayi sterol carrier protein 0.0032 0.0013 0.0013
Mycobacterium tuberculosis Probable cytochrome P450 123 Cyp123 0.0019 0.0003 0.0049
Mycobacterium tuberculosis Inositol-1-monophosphatase SuhB 0.0104 0.0073 0.1596
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0018 0.0002 0.0035
Brugia malayi Niemann-Pick C1 protein precursor 0.0096 0.0066 0.0066
Echinococcus multilocularis biogenic amine (5HT) receptor 0.0021 0.0004 0.0004
Brugia malayi RNA binding protein 0.0129 0.0093 0.0093
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.0056 0.0033 0.0033
Mycobacterium leprae Probable short-chain type dehydrogenase/reductase 0.0023 0.0006 0.0132
Mycobacterium tuberculosis Probable chaperone protein HtpG (heat shock protein) (HSP90 family protein) (high temperature protein G) 0.0083 0.0056 0.1213
Loa Loa (eye worm) G protein signaling regulator EGL-10 0.0038 0.0019 0.0019
Brugia malayi hypothetical protein 0.0021 0.0004 0.0004
Trypanosoma cruzi heat shock protein 90, putative 0.0079 0.0052 0.0069
Schistosoma mansoni short chain dehydrogenase 0.0023 0.0006 0.0006
Loa Loa (eye worm) hypothetical protein 0.0023 0.0006 0.0006
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD35 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.002 0.0004 0.0076
Brugia malayi gonadotropin-releasing hormone receptor 2 0.0021 0.0004 0.0004
Leishmania major heat shock protein 83-1 0.0095 0.0065 0.0087
Echinococcus granulosus G protein coupled 5 hydroxytryptamine receptor 0.0021 0.0004 0.0004
Echinococcus granulosus JmjC domain containing protein 4 0.0043 0.0022 0.0022
Loa Loa (eye worm) hypothetical protein 0.0021 0.0004 0.0004
Mycobacterium tuberculosis Probable fructose-bisphosphate aldolase Fba 0.0289 0.0226 0.4936
Schistosoma mansoni hypothetical protein 0.004 0.002 0.002
Brugia malayi hypothetical protein 0.0018 0.0002 0.0002
Trypanosoma brucei membrane transporter protein, putative 0.0069 0.0044 0.0058
Loa Loa (eye worm) hypothetical protein 0.0043 0.0022 0.0022
Trypanosoma cruzi short chain dehydrogenase, putative 0.0023 0.0006 0.0008
Mycobacterium ulcerans short chain dehydrogenase 0.0023 0.0006 0.0132
Schistosoma mansoni smad 0.0019 0.0003 0.0003
Brugia malayi Cathepsin L-like precursor 0.0018 0.0002 0.0002
Mycobacterium ulcerans long-chain-fatty-acid--CoA ligase 0.0029 0.0011 0.0228
Mycobacterium tuberculosis Possible oxidoreductase 0.0023 0.0006 0.0132
Schistosoma mansoni dihydrolipoamide dehydrogenase 0.0046 0.0025 0.0025
Loa Loa (eye worm) hypothetical protein 0.0018 0.0002 0.0002
Loa Loa (eye worm) heat shock protein 75 0.0053 0.0031 0.0031
Echinococcus multilocularis JmjC domain containing protein 4 0.0043 0.0022 0.0022
Schistosoma mansoni DNA polymerase eta 0.0127 0.0092 0.0092
Schistosoma mansoni Tr4/Tr2 (homologue) 0.0181 0.0136 0.0136
Schistosoma mansoni short chain dehydrogenase 0.0023 0.0006 0.0006
Echinococcus granulosus biogenic amine 5HT receptor 0.0021 0.0004 0.0004
Trypanosoma brucei dihydrolipoyl dehydrogenase 0.0046 0.0025 0.0034
Echinococcus granulosus pyroglutamylated rfamide peptide receptor 0.0021 0.0004 0.0004
Trypanosoma brucei DNA topoisomerase type IB small subunit 0.4613 0.3787 0.5103
Echinococcus granulosus TGF beta signal transducer SmadC 0.0042 0.0022 0.0022
Trypanosoma cruzi trypanothione reductase, putative 0.0046 0.0025 0.0034
Echinococcus multilocularis expressed protein 0.0035 0.0016 0.0016
Trichomonas vaginalis conserved hypothetical protein 0.0021 0.0004 0.008
Giardia lamblia Reductase, putative 0.0023 0.0006 0.0127
Echinococcus granulosus tm gpcr rhodopsin 0.0021 0.0004 0.0004
Mycobacterium ulcerans short chain dehydrogenase 0.0023 0.0006 0.0132
Schistosoma mansoni steroid dehydrogenase 0.0023 0.0006 0.0006
Echinococcus granulosus GPCR family 2 0.0019 0.0003 0.0003
Trypanosoma cruzi 3-keto-dihydrosphingosine reductase 0.0023 0.0006 0.0008
Loa Loa (eye worm) hypothetical protein 0.0021 0.0004 0.0004
Brugia malayi Nuclear hormone receptor family member nhr-31 0.0181 0.0136 0.0136
Loa Loa (eye worm) O-glycosyl hydrolase family 30 protein 0.0278 0.0216 0.0216
Loa Loa (eye worm) hypothetical protein 0.0021 0.0004 0.0004
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0019 0.0003 0.0003
Wolbachia endosymbiont of Brugia malayi 4'-phosphopantetheinyl transferase 0.0167 0.0125 0.5314
Mycobacterium tuberculosis Probable aldehyde dehydrogenase 0.0191 0.0145 0.3164
Echinococcus granulosus caspase 3 0.0149 0.011 0.011
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.0181 0.0136 0.0136
Schistosoma mansoni hypothetical protein 0.0021 0.0004 0.0004
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0069 0.0044 0.0058
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0023 0.0006 0.0132
Trichomonas vaginalis PIKK family atypical protein kinase 0.0026 0.0009 0.0174
Loa Loa (eye worm) hypothetical protein 0.0181 0.0136 0.0136
Plasmodium falciparum cysteine proteinase falcipain 3 0.0018 0.0002 0.0002
Echinococcus multilocularis GTP binding nuclear protein Ran 0.0022 0.0006 0.0006
Loa Loa (eye worm) fibroinase 0.0018 0.0002 0.0002
Trichomonas vaginalis guanylate cyclase, putative 0.0085 0.0057 0.1195
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0048 0.0027 0.0027
Echinococcus multilocularis X box binding protein 1 0.0348 0.0274 0.0274
Toxoplasma gondii histone lysine acetyltransferase GCN5-B 0.0178 0.0134 0.0133
Mycobacterium tuberculosis Possible cytochrome P450 126 Cyp126 0.0019 0.0003 0.0049
Echinococcus granulosus TRP transient receptor potential channel 0.0072 0.0047 0.0047
Onchocerca volvulus 0.0023 0.0006 0.0078
Trichomonas vaginalis PIKK family atypical protein kinase 0.0036 0.0017 0.0346
Leishmania major DNA topoisomerase III, putative 0.0308 0.0241 0.0324
Echinococcus multilocularis nuclear factor of activated T cells 5 0.0079 0.0052 0.0052
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0046 0.0025 0.0034
Loa Loa (eye worm) hypothetical protein 0.0029 0.0011 0.0011
Loa Loa (eye worm) hypothetical protein 0.0181 0.0136 0.0136
Mycobacterium ulcerans cytochrome P450 142A3 Cyp142A3 0.0019 0.0003 0.0049
Schistosoma mansoni heat shock protein 0.0095 0.0065 0.0065
Loa Loa (eye worm) hypothetical protein 0.0016 0.0001 0.0001
Schistosoma mansoni amine GPCR 0.0021 0.0004 0.0004
Echinococcus granulosus segment polarity protein dishevelled 0.0018 0.0002 0.0002
Entamoeba histolytica hypothetical protein 0.0021 0.0004 0.0045
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0181 0.0136 0.0136
Brugia malayi MH1 domain containing protein 0.0023 0.0006 0.0006
Trypanosoma cruzi DNA topoisomerase IA, putative 0.0257 0.0199 0.0268
Giardia lamblia PHD finger protein 15 0.0029 0.0011 0.0232
Echinococcus granulosus transcription factor Dp 1 0.0039 0.002 0.002
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0064 0.004 0.004
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0023 0.0006 0.0006
Trypanosoma brucei unspecified product 0.0095 0.0065 0.0087
Echinococcus multilocularis g-protein coupled receptor 0.0021 0.0004 0.0004
Echinococcus multilocularis protein dispatched 1 0.0047 0.0026 0.0026
Trypanosoma cruzi mitogen activated protein kinase 4, putative 0.0051 0.0029 0.0039
Brugia malayi Hypothetical 22.2 kDa protein C28F5.2 in chromosome II, putative 0.0027 0.0009 0.0009
Trypanosoma brucei hypothetical protein, conserved 0.0167 0.0125 0.0168
Plasmodium falciparum GTP-binding nuclear protein RAN/TC4 0.0022 0.0006 0.0005
Mycobacterium ulcerans cytochrome P450 124A1, Cyp124A1 0.0019 0.0003 0.0049
Schistosoma mansoni short chain dehydrogenase 0.0023 0.0006 0.0006
Brugia malayi MH1 domain containing protein 0.0023 0.0006 0.0006
Echinococcus granulosus smad 0.0042 0.0022 0.0022
Brugia malayi AMP-binding enzyme family protein 0.0029 0.0011 0.0011
Loa Loa (eye worm) hypothetical protein 0.0032 0.0013 0.0013
Trypanosoma brucei isocitrate dehydrogenase, putative 0.0097 0.0067 0.009
Brugia malayi DNA topoisomerase III 0.0265 0.0205 0.0205
Toxoplasma gondii melibiase subfamily protein 0.021 0.016 0.016
Onchocerca volvulus 0.0021 0.0004 0.004
Echinococcus multilocularis A kinase anchor protein 10, mitochondrial 0.0021 0.0004 0.0004
Leishmania major cathepsin L-like protease 0.0069 0.0044 0.0058
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0018 0.0002 0.0035
Loa Loa (eye worm) hypothetical protein 0.0021 0.0004 0.0004
Schistosoma mansoni smad 0.0042 0.0022 0.0022
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0019 0.0003 0.0003
Brugia malayi hypothetical protein 0.1022 0.0829 0.0829
Brugia malayi jmjC domain containing protein 0.0043 0.0022 0.0022
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0061 0.0038 0.0814
Brugia malayi hypothetical protein 0.0021 0.0004 0.0004
Echinococcus multilocularis mothers against decapentaplegic 2 0.0019 0.0003 0.0003
Brugia malayi alpha keto acid dehydrogenase complex, E3 component, lipoamide dehydrogenase 0.0034 0.0015 0.0015
Loa Loa (eye worm) hypothetical protein 0.0018 0.0002 0.0002
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0021 0.0004 0.0004
Leishmania major isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0097 0.0067 0.009
Echinococcus multilocularis alpha 1A adrenergic receptor 0.0021 0.0004 0.0004
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.0023 0.0006 0.0007
Brugia malayi dehydrogenases, short chain protein 2 0.0023 0.0006 0.0006
Schistosoma mansoni oxidoreductase short chain dehydrogenase/reductase family 0.0023 0.0006 0.0006
Loa Loa (eye worm) hypothetical protein 0.0023 0.0006 0.0006
Toxoplasma gondii hypothetical protein 0.0018 0.0002 0.0001
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0018 0.0002 0.0035
Echinococcus granulosus jumonji domain containing 1A 0.0043 0.0022 0.0022
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0021 0.0004 0.0004
Schistosoma mansoni short chain dehydrogenase 0.0023 0.0006 0.0006
Echinococcus multilocularis smad 0.0042 0.0022 0.0022
Mycobacterium tuberculosis Probable oxidoreductase 0.0023 0.0006 0.0132
Echinococcus multilocularis FTZ F1 alpha 0.0181 0.0136 0.0136
Mycobacterium leprae DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE 0.0339 0.0267 0.5838
Mycobacterium ulcerans (3R)-hydroxyacyl-ACP dehydratase subunit HadC 0.0032 0.0014 0.0286
Echinococcus granulosus neuropeptides capa receptor 0.0021 0.0004 0.0004
Echinococcus granulosus sex peptide receptor 0.0021 0.0004 0.0004
Trichomonas vaginalis conserved hypothetical protein 0.0091 0.0062 0.1298
Leishmania major tyrosyl-DNA phosphodiesterase 1 0.0068 0.0043 0.0058
Loa Loa (eye worm) hypothetical protein 0.0085 0.0057 0.0057
Brugia malayi Dopamine receptor protein 1 0.0021 0.0004 0.0004
Schistosoma mansoni peptide (allatostatin)-like receptor 0.0021 0.0004 0.0004
Trichomonas vaginalis glucosylceramidase, putative 0.0182 0.0137 0.2881
Plasmodium falciparum DNA topoisomerase 3, putative 0.0257 0.0199 0.0199
Echinococcus multilocularis inositol monophosphatase 1 0.0117 0.0083 0.0083
Schistosoma mansoni hypothetical protein 0.0018 0.0002 0.0002
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0117 0.0083 0.1745
Toxoplasma gondii oxidoreductase, short chain dehydrogenase/reductase family protein 0.0023 0.0006 0.0006
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0069 0.0044 0.0058
Trichomonas vaginalis conserved hypothetical protein 0.0021 0.0004 0.008
Brugia malayi nuclear receptor RXR 0.0085 0.0058 0.0058
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0091 0.0062 0.1298
Trypanosoma cruzi DNA topoisomerase IA, putative 0.0257 0.0199 0.0268
Trypanosoma cruzi Heat shock protein 83, putative 0.0095 0.0065 0.0087
Echinococcus granulosus peptide allatostatin:somatostatin 0.0021 0.0004 0.0004
Schistosoma mansoni cytochrome P450 0.0019 0.0003 0.0003
Onchocerca volvulus 0.0023 0.0006 0.0078
Brugia malayi Isocitrate dehydrogenase 0.0097 0.0067 0.0067
Mycobacterium ulcerans extragenic suppressor protein SuhB 0.0117 0.0083 0.1816
Echinococcus multilocularis rhodopsin orphan GPCR 0.0021 0.0004 0.0004
Trypanosoma brucei DNA polymerase kappa, putative 0.0101 0.0071 0.0095
Echinococcus multilocularis citrate lyase subunit beta protein 0.0026 0.0009 0.0009
Trypanosoma cruzi short chain dehydrogenase/reductase, putative 0.0023 0.0006 0.0008
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.0181 0.0136 0.2296
Echinococcus granulosus rhodopsin orphan GPCR 0.0021 0.0004 0.0004
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0023 0.0006 0.0006
Wolbachia endosymbiont of Brugia malayi dihydrolipoamide dehydrogenase E3 component 0.0046 0.0025 0.1067
Mycobacterium tuberculosis Probable dehydrogenase/reductase 0.0023 0.0006 0.0132
Mycobacterium ulcerans short chain dehydrogenase 0.0023 0.0006 0.0132
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0046 0.0025 0.0034
Schistosoma mansoni hypothetical protein 0.0021 0.0004 0.0004
Trypanosoma cruzi oxidoreductase-like protein, putative 0.0023 0.0006 0.0008
Echinococcus multilocularis carbonyl reductase 1 0.0023 0.0006 0.0006
Onchocerca volvulus 0.0595 0.0478 0.8121
Schistosoma mansoni peptide (allatostatin/somatostatin)-like receptor 0.0021 0.0004 0.0004
Leishmania major cytochrome p450-like protein 0.0046 0.0025 0.0033
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0097 0.0067 0.0067
Echinococcus granulosus neuropeptide receptor 0.0021 0.0004 0.0004
Loa Loa (eye worm) hypothetical protein 0.0021 0.0004 0.0004
Leishmania major hypothetical protein, conserved 0.0023 0.0006 0.0008
Brugia malayi nuclear hormone receptor family member nhr-6 0.0085 0.0058 0.0058
Echinococcus multilocularis PHD finger protein rhinoceros 0.0029 0.0011 0.0011
Loa Loa (eye worm) PHD-finger family protein 0.0029 0.0011 0.0011
Mycobacterium leprae conserved hypothetical protein 0.0167 0.0125 0.2733
Schistosoma mansoni hypothetical protein 0.0021 0.0004 0.0004
Loa Loa (eye worm) hypothetical protein 0.0021 0.0004 0.0004
Plasmodium vivax endoplasmin, putative 0.0095 0.0065 0.0065
Onchocerca volvulus Cathepsin L homolog 0.0018 0.0002 0.0003
Echinococcus granulosus citrate lyase subunit beta protein 0.0026 0.0009 0.0009
Echinococcus multilocularis short transient receptor potential channel 6 0.0128 0.0093 0.0093
Loa Loa (eye worm) hypothetical protein 0.0085 0.0058 0.0058
Mycobacterium tuberculosis Probable cytochrome P450 143 Cyp143 0.0019 0.0003 0.0049
Brugia malayi hypothetical protein 0.0018 0.0002 0.0002
Mycobacterium tuberculosis Probable cytochrome P450 139 Cyp139 0.0019 0.0003 0.0049
Plasmodium vivax isocitrate dehydrogenase [NADP], mitochondrial, putative 0.0097 0.0067 0.0067
Echinococcus multilocularis transient receptor potential cation channel 0.0023 0.0006 0.0006
Schistosoma mansoni zinc finger protein 0.0085 0.0058 0.0058
Echinococcus multilocularis dna polymerase kappa 0.0101 0.0071 0.0071
Loa Loa (eye worm) hypothetical protein 0.0181 0.0136 0.0136
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0018 0.0002 0.0002
Trichomonas vaginalis histone acetyltransferase gcn5, putative 0.0017 0.0001 0.0016
Echinococcus granulosus Ataxin 2 N terminaldomain containing protein 0.0059 0.0036 0.0036
Trypanosoma brucei 3-keto-dihydrosphingosine reductase 0.0023 0.0006 0.0008
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0125 0.009 0.009
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0018 0.0002 0.0035
Echinococcus granulosus rhodopsin orphan GPCR 0.0021 0.0004 0.0004
Loa Loa (eye worm) hypothetical protein 0.0027 0.0009 0.0009
Mycobacterium leprae PROBABLE CHAPERONE PROTEIN HTPG (HEAT SHOCK PROTEIN) (HSP90 FAMILY PROTEIN) (HIGH TEMPERATURE PROTEIN G) 0.0083 0.0056 0.1213
Echinococcus multilocularis SAM and MBT domain containing protein 0.0047 0.0026 0.0026
Mycobacterium leprae PROBABLE NADH DEHYDROGENASE NDH 0.0305 0.0239 0.5223
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0046 0.0025 0.0034
Echinococcus granulosus Nuclear hormone receptor HR96 0.0085 0.0058 0.0058
Loa Loa (eye worm) hypothetical protein 0.0055 0.0033 0.0032
Echinococcus multilocularis fmrfamide receptor 0.0021 0.0004 0.0004
Brugia malayi hypothetical protein 0.1461 0.1191 0.1191
Schistosoma mansoni steroid dehydrogenase 0.0023 0.0006 0.0006
Schistosoma mansoni globin X 0.0027 0.0009 0.0009
Trypanosoma cruzi 2,4-dihydroxyhept-2-ene-1,7-dioic acid aldolase, putative 0.0026 0.0009 0.0011
Schistosoma mansoni phosphatidylinositol 3-and 4-kinase 0.0016 0.0001 0.0001
Brugia malayi Steroid receptor seven-up type 2 0.0181 0.0136 0.0136
Mycobacterium ulcerans cytochrome P450 125A7 Cyp125A7 0.0019 0.0003 0.0049
Brugia malayi mothers against decapentaplegic homolog 3 0.0019 0.0003 0.0003
Leishmania major quinonoid dihydropteridine reductase 0.0023 0.0006 0.0008
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD3 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.002 0.0004 0.0076
Echinococcus multilocularis importin subunit beta 1 0.003 0.0012 0.0012
Schistosoma mansoni hypothetical protein 0.0017 0.0001 0.0001
Schistosoma mansoni tar DNA-binding protein 0.0129 0.0093 0.0093
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0061 0.0037 0.0037
Echinococcus multilocularis Kelch repeat type 1 0.0095 0.0065 0.0065
Schistosoma mansoni hypothetical protein 0.0027 0.0009 0.0009
Onchocerca volvulus Cathepsin F homolog 0.0018 0.0002 0.0003
Mycobacterium tuberculosis DNA topoisomerase I TopA (omega-protein) (relaxing enzyme) (untwisting enzyme) (swivelase) (type I DNA topoisomerase) (nicking-c 0.0123 0.0089 0.1936
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0085 0.0058 0.0058
Echinococcus granulosus mothers against decapentaplegic 6 0.0019 0.0003 0.0003
Leishmania major ATP-binding cassette protein subfamily G, member 4, putative 0.002 0.0004 0.0004
Trichomonas vaginalis glucosylceramidase, putative 0.0182 0.0137 0.2881
Echinococcus multilocularis serotonin receptor 0.0021 0.0004 0.0004
Trichomonas vaginalis PIKK family atypical protein kinase 0.0036 0.0017 0.0346
Loa Loa (eye worm) hypothetical protein 0.0085 0.0058 0.0058
Onchocerca volvulus Dehydrogenase\/reductase SDR family member 1 homolog 0.0023 0.0006 0.0078
Schistosoma mansoni transient receptor potential channel 0.0194 0.0147 0.0147
Leishmania major hypothetical protein, conserved 0.0043 0.0022 0.003
Plasmodium vivax ataxin-2 like protein, putative 0.0131 0.0095 0.0095
Trichomonas vaginalis sucrase-isomaltase, putative 0.0084 0.0057 0.1181
Leishmania major trypanothione reductase 0.0134 0.0098 0.0131
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.0181 0.0136 0.0136
Trypanosoma cruzi glycosyl hydrolase-like protein, putative 0.0031 0.0013 0.0017
Trypanosoma brucei heat shock protein, putative 0.0095 0.0065 0.0087
Onchocerca volvulus 0.0085 0.0058 0.0951
Schistosoma mansoni hypothetical protein 0.0019 0.0003 0.0003
Echinococcus multilocularis flap endonuclease 1 0.0027 0.001 0.001
Trichomonas vaginalis mercuric reductase, putative 0.0046 0.0025 0.0527
Echinococcus granulosus short transient receptor potential channel 6 0.0128 0.0093 0.0093
Loa Loa (eye worm) hypothetical protein 0.0122 0.0088 0.0088
Brugia malayi PAS domain containing protein 0.0305 0.0238 0.0238
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0592 0.0475 1
Schistosoma mansoni caspase-7 (C14 family) 0.024 0.0185 0.0185
Schistosoma mansoni short chain dehydrogenase 0.0023 0.0006 0.0006
Echinococcus multilocularis Smad4 0.0042 0.0022 0.0022
Mycobacterium tuberculosis Probable cytochrome P450 132 Cyp132 0.0019 0.0003 0.0049
Mycobacterium tuberculosis Probable NADH dehydrogenase Ndh 0.0305 0.0239 0.5223
Brugia malayi Globin family protein 0.0027 0.0009 0.0009
Brugia malayi Hypothetical oxidoreductase F56D1.5 0.0023 0.0006 0.0006
Trypanosoma cruzi heat shock protein 85, putative 0.0095 0.0065 0.0087
Brugia malayi Cytochrome P450 family protein 0.0039 0.002 0.002
Trichomonas vaginalis cat eye syndrome critical region protein 2, cscr2, putative 0.0178 0.0134 0.2804
Trichomonas vaginalis conserved hypothetical protein 0.0041 0.0021 0.0438
Loa Loa (eye worm) Papain cysteine protease/cathepsin propeptide inhibitor-containing protein 0.0018 0.0002 0.0002
Leishmania major 4-coumarate:coa ligase-like protein 0.0029 0.0011 0.0014
Trichomonas vaginalis conserved hypothetical protein 0.0091 0.0062 0.1298
Loa Loa (eye worm) neuropeptide F receptor 0.0021 0.0004 0.0004
Mycobacterium ulcerans short chain dehydrogenase 0.0023 0.0006 0.0132
Trypanosoma brucei dihydrolipoamide dehydrogenase, point mutation 0.0046 0.0025 0.0034
Schistosoma mansoni thyroid hormone receptor 0.0181 0.0136 0.0136
Mycobacterium ulcerans ketoacyl reductase 0.0023 0.0006 0.0132
Trypanosoma cruzi STE/STE11 serine/threonine-protein kinase, putative 0.0086 0.0059 0.0078
Brugia malayi Nuclear hormone receptor family member nhr-49 0.0181 0.0136 0.0136
Onchocerca volvulus 0.0018 0.0002 0.0004
Brugia malayi DNA topoisomerase II, alpha isozyme 0.0074 0.0049 0.0049
Leishmania major short chain dehydrogenase, putative 0.0023 0.0006 0.0008
Entamoeba histolytica glycosyl hydrolase, family 31 protein 0.0084 0.0057 0.1151
Trichomonas vaginalis maltase-glucoamylase, putative 0.0084 0.0057 0.1181
Brugia malayi Unidentified vitellogenin-linked transcript protein 6, putative 0.0021 0.0004 0.0004
Giardia lamblia DNA topoisomerase III 0.0134 0.0098 0.2048
Echinococcus granulosus ATP binding cassette sub family G 0.002 0.0004 0.0004
Trypanosoma brucei short-chain dehydrogenase, putative 0.0023 0.0006 0.0008
Trypanosoma cruzi isocitrate dehydrogenase, putative 0.0097 0.0067 0.009
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0181 0.0136 0.0136
Schistosoma mansoni transient receptor potential channel 0.0128 0.0093 0.0093
Trichomonas vaginalis PIKK family atypical protein kinase 0.0029 0.0011 0.0223
Loa Loa (eye worm) G-protein coupled receptor 0.0021 0.0004 0.0004
Plasmodium falciparum thioredoxin reductase 0.0046 0.0025 0.0025
Brugia malayi PXA domain containing protein 0.0021 0.0004 0.0004
Echinococcus multilocularis 3 ketodihydrosphingosine reductase 0.0023 0.0006 0.0006
Loa Loa (eye worm) hypothetical protein 0.0018 0.0002 0.0002
Echinococcus granulosus epidermal retinal dehydrogenase 2 0.0023 0.0006 0.0006
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0018 0.0002 0.0035
Schistosoma mansoni short chain dehydrogenase 0.0023 0.0006 0.0006
Mycobacterium ulcerans hypothetical protein 0.0032 0.0014 0.0286
Plasmodium falciparum steroid dehydrogenase, putative 0.0023 0.0006 0.0006
Leishmania major heat shock protein 83-1 0.0095 0.0065 0.0087
Mycobacterium tuberculosis NAD(P)H quinone reductase LpdA 0.0339 0.0267 0.5838
Trichomonas vaginalis CAMK family protein kinase 0.0195 0.0148 0.3102
Echinococcus granulosus orexin receptor type 2 0.0021 0.0004 0.0004
Trypanosoma cruzi short chain dehydrogenase, putative 0.0023 0.0006 0.0008
Loa Loa (eye worm) ctsf protein 0.0018 0.0002 0.0002
Brugia malayi TAR-binding protein 0.0129 0.0093 0.0093
Brugia malayi Nuclear hormone receptor-like 1 0.0181 0.0136 0.0136
Echinococcus granulosus cathepsin l1 0.0018 0.0002 0.0002
Onchocerca volvulus 0.0029 0.0011 0.0153
Schistosoma mansoni zinc finger protein 0.0018 0.0002 0.0002
Echinococcus multilocularis cathepsin l cysteine peptidase 0.0018 0.0002 0.0002
Echinococcus multilocularis retinol dehydrogenase 11 0.0023 0.0006 0.0006
Schistosoma mansoni ABC transporter 0.0017 0.0001 0.0001
Entamoeba histolytica heat shock protein 90, putative 0.0095 0.0065 0.1333
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase domain containing protein 0.0045 0.0024 0.0464
Echinococcus multilocularis isocitrate dehydrogenase 0.0097 0.0067 0.0067
Echinococcus granulosus fmrfamide receptor 0.0021 0.0004 0.0004
Loa Loa (eye worm) hypothetical protein 0.0131 0.0095 0.0095
Schistosoma mansoni hypothetical protein 0.0019 0.0003 0.0003
Loa Loa (eye worm) nuclear receptor NHR-67 0.0085 0.0058 0.0058
Onchocerca volvulus Dopamine\/Ecdysteroid receptor homolog 0.0021 0.0004 0.004
Leishmania major DNA polymerase kappa, putative 0.0023 0.0006 0.0008
Toxoplasma gondii DNA topoisomerase I, putative 1.2154 1 1
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0018 0.0002 0.0035
Loa Loa (eye worm) hypothetical protein 0.0021 0.0004 0.0004
Schistosoma mansoni ubiquitously transcribed sex (X/Y) chromosome tetratricopeptide repeat protein-related 0.0043 0.0022 0.0022
Schistosoma mansoni alpha-galactosidase/alpha-n-acetylgalactosaminidase 0.021 0.016 0.016
Mycobacterium tuberculosis Probable oxidoreductase 0.0023 0.0006 0.0132
Brugia malayi Helix-loop-helix DNA-binding domain containing protein 0.0018 0.0002 0.0002
Schistosoma mansoni apoferritin-2 0.0035 0.0016 0.0016
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.0181 0.0136 0.0136
Plasmodium vivax AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0023 0.0006 0.0006
Loa Loa (eye worm) hypothetical protein 0.003 0.0012 0.0012
Echinococcus granulosus histone acetyltransferase MYST2 0.0053 0.0031 0.0031
Loa Loa (eye worm) hypothetical protein 0.0085 0.0058 0.0058
Trypanosoma cruzi cysteine peptidase, putative 0.0018 0.0002 0.0002
Loa Loa (eye worm) nuclear factor I 0.0023 0.0006 0.0006
Mycobacterium ulcerans hypothetical protein 0.0032 0.0014 0.0286
Echinococcus granulosus transient receptor potential gamma protein 0.0194 0.0147 0.0147
Schistosoma mansoni neuropeptide receptor 0.0021 0.0004 0.0004
Mycobacterium leprae putative cytochrome p450 0.0019 0.0003 0.0049
Mycobacterium ulcerans short chain dehydrogenase 0.0023 0.0006 0.0132
Trypanosoma cruzi heat shock protein 85, putative 0.0095 0.0065 0.0087
Trypanosoma cruzi STE/STE11 serine/threonine-protein kinase, putative 0.0086 0.0059 0.0078
Schistosoma mansoni rab geranylgeranyl transferase alpha subunit 0.0074 0.0048 0.0048
Echinococcus granulosus NADP dependent isocitrate dehydrogenase 0.0097 0.0067 0.0067
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0592 0.0475 1
Mycobacterium ulcerans short chain dehydrogenase 0.0023 0.0006 0.0132
Brugia malayi Cathepsin L-like precursor 0.0018 0.0002 0.0002
Toxoplasma gondii DNA topoisomerase domain-containing protein 0.0178 0.0134 0.0133
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0019 0.0003 0.0003
Brugia malayi Glycosyl hydrolases family 31 protein 0.0319 0.025 0.025
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0069 0.0044 0.0058
Trichomonas vaginalis alpha-glucosidase, putative 0.0084 0.0057 0.1181
Echinococcus multilocularis peregrin 0.0044 0.0024 0.0024
Trypanosoma brucei hypothetical protein, conserved 0.0023 0.0006 0.0008
Mycobacterium ulcerans cytochrome P450 187A4 Cyp187A4 0.0019 0.0003 0.0049
Trichomonas vaginalis DNA polymerase eta, putative 0.0101 0.0071 0.1483
Loa Loa (eye worm) hypothetical protein 0.0021 0.0005 0.0005
Loa Loa (eye worm) hypothetical protein 0.0018 0.0002 0.0002
Schistosoma mansoni transient receptor potential channel 4 0.0194 0.0147 0.0147
Echinococcus multilocularis g protein coupled receptor 0.0021 0.0004 0.0004
Mycobacterium leprae possible inositol monophosphatase SubH (IMPase) (inositol-1-phosphatase) (I-1-Pase ). 0.0104 0.0073 0.1596
Echinococcus multilocularis jun protein 0.0084 0.0056 0.0056
Onchocerca volvulus Polycomb protein Sfmbt homolog 0.0047 0.0026 0.0405
Brugia malayi MH2 domain containing protein 0.0042 0.0022 0.0022
Echinococcus granulosus nuclear receptor nhr 48 0.0085 0.0058 0.0058
Plasmodium falciparum acyl-CoA synthetase 0.0021 0.0005 0.0004
Mycobacterium ulcerans hypothetical protein 0.0026 0.0009 0.0177
Onchocerca volvulus Glucosylceramidase homolog 0.0182 0.0137 0.2311
Mycobacterium ulcerans dehydrogenase 0.0023 0.0006 0.0132
Schistosoma mansoni cathepsin F (C01 family) 0.0018 0.0002 0.0002
Echinococcus granulosus dihydrolipoamide dehydrogenase 0.0046 0.0025 0.0025
Brugia malayi mbt repeat family protein 0.0047 0.0026 0.0026
Trypanosoma brucei chrX additional, unordered contigs 0.0023 0.0006 0.0008
Schistosoma mansoni flap endonuclease-1 0.0025 0.0008 0.0008
Echinococcus granulosus retinoic acid receptor rxr beta a 0.0181 0.0136 0.0136
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0085 0.0058 0.0058
Onchocerca volvulus Cell death protein 3 homolog 0.0175 0.0132 0.2217
Onchocerca volvulus 0.0018 0.0002 0.0003
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0189 0.0143 0.3122
Chlamydia trachomatis DNA gyrase subunit B 0.0074 0.0049 0.1894
Wolbachia endosymbiont of Brugia malayi exonuclease III 0.0023 0.0006 0.0236
Brugia malayi PHD-finger family protein 0.0018 0.0002 0.0002
Toxoplasma gondii thioredoxin reductase 0.0134 0.0098 0.0097
Onchocerca volvulus 0.0018 0.0002 0.0003
Schistosoma mansoni subfamily C14A unassigned peptidase (C14 family) 0.0091 0.0062 0.0062
Echinococcus multilocularis multidrug and toxin extrusion protein 2 0.0069 0.0044 0.0044
Toxoplasma gondii LsmAD domain-containing protein 0.0131 0.0095 0.0095
Schistosoma mansoni kinase 0.0099 0.0069 0.0069
Echinococcus granulosus FKBP12 rapamycin complex associated protein 0.0048 0.0027 0.0027
Echinococcus granulosus cytoplasmic intermediate filament protein 0.0027 0.001 0.001
Echinococcus granulosus microtubule associated protein 2 0.2077 0.1698 0.1698
Loa Loa (eye worm) RNA recognition domain-containing protein domain-containing protein 0.0129 0.0093 0.0093
Brugia malayi Globin family protein 0.0027 0.0009 0.0009
Echinococcus granulosus neuropeptide FF receptor 2 0.0021 0.0004 0.0004
Loa Loa (eye worm) cytochrome P450 family protein 0.0039 0.002 0.0019
Loa Loa (eye worm) hypothetical protein 0.0085 0.0058 0.0058
Entamoeba histolytica 90 kDa heat shock protein, putative 0.0053 0.0031 0.0607
Loa Loa (eye worm) DIX domain-containing protein 0.0018 0.0002 0.0002
Schistosoma mansoni hypothetical protein 0.0288 0.0224 0.0224
Loa Loa (eye worm) hypothetical protein 0.0021 0.0004 0.0004
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0048 0.0027 0.0027
Entamoeba histolytica hypothetical protein 0.0167 0.0125 0.26
Leishmania major cytochrome p450-like protein 0.0019 0.0003 0.0003
Loa Loa (eye worm) hypothetical protein 0.0181 0.0136 0.0136
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0031 0.0013 0.0266
Echinococcus granulosus WW domain containing oxidoreductase 0.0023 0.0006 0.0006
Trichomonas vaginalis glucosylceramidase, putative 0.0182 0.0137 0.2881
Schistosoma mansoni heat shock protein 0.0095 0.0065 0.0065
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.002 0.0004 0.0004
Chlamydia trachomatis DNA gyrase subunit B 0.0074 0.0049 0.1894
Brugia malayi G-protein coupled receptor 0.0021 0.0004 0.0004
Onchocerca volvulus 0.0085 0.0058 0.0951
Giardia lamblia DINP protein human, muc B family 0.0081 0.0054 0.1126
Echinococcus granulosus MAM 0.0019 0.0003 0.0003
Echinococcus granulosus muscleblind protein 0.0619 0.0498 0.0498
Toxoplasma gondii PHD-finger domain-containing protein 0.0029 0.0011 0.0011
Onchocerca volvulus 0.0134 0.0098 0.1635
Loa Loa (eye worm) hypothetical protein 0.0021 0.0004 0.0004
Toxoplasma gondii aldehyde dehydrogenase 0.0191 0.0145 0.0144
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0026 0.0009 0.0009
Loa Loa (eye worm) hypothetical protein 0.0383 0.0303 0.0302
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.0181 0.0136 0.0136
Loa Loa (eye worm) hypothetical protein 0.0021 0.0005 0.0005
Trypanosoma brucei metacaspase 5, putative 0.0091 0.0062 0.0083
Echinococcus multilocularis ATP binding cassette sub family G 0.002 0.0004 0.0004
Loa Loa (eye worm) dehydrogenase 0.0023 0.0006 0.0006
Toxoplasma gondii oxidoreductase, putative 0.0023 0.0006 0.0006
Leishmania major hypothetical protein, conserved 0.0022 0.0006 0.0007
Plasmodium vivax hypothetical protein, conserved 0.0023 0.0006 0.0006
Echinococcus granulosus neuropeptide receptor 0.0021 0.0004 0.0004
Brugia malayi DIX domain containing protein 0.0018 0.0002 0.0002
Echinococcus multilocularis lysine specific demethylase 6a 0.0043 0.0022 0.0022
Echinococcus granulosus retinol dehydrogenase 11 0.0023 0.0006 0.0006
Echinococcus multilocularis caspase 3 0.0149 0.011 0.011
Brugia malayi Nuclear hormone receptor family member nhr-40 0.0181 0.0136 0.0136
Mycobacterium ulcerans DNA polymerase IV 0.0101 0.0071 0.1543
Leishmania major quinonoid dihydropteridine reductase 0.0023 0.0006 0.0008
Mycobacterium ulcerans long-chain-fatty-acid-CoA ligase 0.0029 0.0011 0.0228
Trypanosoma cruzi metacaspase, putative 0.0091 0.0062 0.0083
Toxoplasma gondii ICE family protease (caspase) p20 domain-containing protein 0.0091 0.0062 0.0062
Trypanosoma cruzi DNA topoisomerase type IB small subunit, putative 0.4613 0.3787 0.5103
Loa Loa (eye worm) phosphatidylinositol 3 0.0048 0.0027 0.0027
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0018 0.0002 0.0035
Echinococcus multilocularis G protein coupled receptor 139 0.0021 0.0004 0.0004
Mycobacterium ulcerans short chain dehydrogenase 0.0023 0.0006 0.0132
Loa Loa (eye worm) hypothetical protein 0.0027 0.0009 0.0009
Echinococcus granulosus somatostatin receptor 0.0021 0.0004 0.0004
Brugia malayi A-kinase anchor protein 10, precursor 0.0021 0.0004 0.0004
Brugia malayi Nuclear hormone receptor family member nhr-14 0.0181 0.0136 0.0136
Mycobacterium ulcerans 3-ketoacyl-ACP reductase 0.0023 0.0006 0.0132
Loa Loa (eye worm) hypothetical protein 0.0021 0.0004 0.0004
Trypanosoma cruzi metacaspase, putative 0.0091 0.0062 0.0083
Loa Loa (eye worm) hypothetical protein 0.0021 0.0004 0.0004
Echinococcus granulosus lysine specific demethylase 6a 0.0043 0.0022 0.0022
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0018 0.0002 0.0035
Trypanosoma brucei polo-like protein kinase 0.0195 0.0148 0.0199
Brugia malayi Flap endonuclease-1 0.0027 0.001 0.001
Entamoeba histolytica hypothetical protein 0.0025 0.0008 0.0115
Mycobacterium tuberculosis Possible fatty acyl-CoA reductase 0.0023 0.0006 0.0132
Onchocerca volvulus Putative DNA topoisomerase 2, mitochondrial 0.0074 0.0049 0.0796
Leishmania major quinonoid dihydropteridine reductase 0.0023 0.0006 0.0008
Schistosoma mansoni alpha-galactosidase/alpha-n-acetylgalactosaminidase 0.003 0.0012 0.0012
Leishmania major heat shock protein 83-1 0.0095 0.0065 0.0087
Brugia malayi Cathepsin L-like precursor 0.0018 0.0002 0.0002
Leishmania major hypothetical protein, conserved 0.0069 0.0044 0.0058
Echinococcus granulosus steroid dehydrogenase 0.0023 0.0006 0.0006
Echinococcus granulosus 7tm_1 domain containing protein 0.0021 0.0004 0.0004
Brugia malayi serine/threonine-protein kinase plk-2 0.0195 0.0148 0.0148
Brugia malayi regulator of G-protein signaling egl-10 0.0038 0.0019 0.0019
Entamoeba histolytica hypothetical protein, conserved 0.0023 0.0006 0.0093
Plasmodium falciparum glutathione reductase 0.0134 0.0098 0.0097
Brugia malayi Nuclear hormone receptor-like 1 0.0096 0.0066 0.0066
Toxoplasma gondii Hsp90 domain-containing protein 0.0226 0.0173 0.0173
Loa Loa (eye worm) hypothetical protein 0.0096 0.0066 0.0066
Mycobacterium ulcerans cytochrome P450 189A7 Cyp189A7 0.0019 0.0003 0.0049
Echinococcus granulosus hypothetical protein 0.0023 0.0006 0.0006
Schistosoma mansoni nuclear receptor nhr-48 0.0085 0.0058 0.0058
Mycobacterium ulcerans flavoprotein disulfide reductase 0.0046 0.0025 0.0549
Schistosoma mansoni bromodomain containing protein 0.0018 0.0002 0.0002
Schistosoma mansoni phd/f-box containing protein 0.0043 0.0022 0.0022
Plasmodium vivax heat shock protein 90, putative 0.0053 0.0031 0.003
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0018 0.0002 0.0035
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0091 0.0062 0.1298
Mycobacterium tuberculosis Probable dehydrogenase 0.0305 0.0239 0.5223
Plasmodium falciparum thioredoxin reductase 0.0134 0.0098 0.0097
Echinococcus multilocularis neuropeptide FF receptor 2 0.0021 0.0004 0.0004
Brugia malayi Importin beta-1 subunit 0.003 0.0012 0.0012
Giardia lamblia Ubiquitin carboxyl-terminal hydrolase 4 0.0045 0.0024 0.0497
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0018 0.0002 0.0035
Loa Loa (eye worm) hypothetical protein 0.0023 0.0006 0.0006
Echinococcus granulosus aryl hydrocarbon receptor 0.0103 0.0072 0.0072
Echinococcus multilocularis geminin 0.1214 0.0988 0.0988
Echinococcus granulosus caspase 0.024 0.0185 0.0185
Loa Loa (eye worm) hypothetical protein 0.0096 0.0066 0.0066
Echinococcus granulosus expressed conserved protein 0.009 0.0062 0.0062
Entamoeba histolytica myo-inositol monophosphatase, putative 0.0117 0.0083 0.1716
Echinococcus multilocularis sex peptide receptor 0.0021 0.0004 0.0004
Brugia malayi Melatonin receptor type 1A 0.0021 0.0004 0.0004
Schistosoma mansoni retinoic acid receptor RXR 0.0181 0.0136 0.0136
Mycobacterium tuberculosis Probable dehydrogenase 0.0023 0.0006 0.0132
Schistosoma mansoni prokaryotic DNA topoisomerase 0.0134 0.0098 0.0098
Trypanosoma cruzi DNA damage repair protein, putative 0.0023 0.0006 0.0008
Leishmania major cathepsin L-like protease 0.0018 0.0002 0.0002
Mycobacterium ulcerans aldehyde dehydrogenase 0.0191 0.0145 0.3164
Plasmodium falciparum topoisomerase I 1.2154 1 1
Schistosoma mansoni alpha-galactosidase/alpha-n-acetylgalactosaminidase 0.021 0.016 0.016
Loa Loa (eye worm) 5-hydroxytryptamine 2C receptor 0.0021 0.0004 0.0004
Loa Loa (eye worm) CAMK/CAMKL/CHK1 protein kinase 0.0181 0.0136 0.0136
Schistosoma mansoni alpha glucosidase 0.0084 0.0057 0.0057
Onchocerca volvulus 0.0058 0.0035 0.0565
Trichomonas vaginalis CMGC family protein kinase 0.0051 0.0029 0.0611
Toxoplasma gondii heat shock protein HSP90 0.0095 0.0065 0.0065
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0021 0.0004 0.0004
Trypanosoma cruzi metacaspase, putative 0.0091 0.0062 0.0083
Plasmodium vivax hypothetical protein, conserved 0.0091 0.0062 0.0062
Mycobacterium ulcerans transmembrane ABC transporter ATP-binding protein 0.002 0.0004 0.0071
Onchocerca volvulus 0.0021 0.0004 0.004
Echinococcus multilocularis cysteine protease 0.0018 0.0002 0.0002
Schistosoma mansoni hypothetical protein 0.0019 0.0003 0.0003
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0023 0.0006 0.0132
Mycobacterium leprae Conserved hypothetical protein 0.0019 0.0003 0.0049
Mycobacterium ulcerans short-chain dehydrogenase 0.0023 0.0006 0.0132
Echinococcus multilocularis phosphatidylinositol 3 and 4 kinase 0.0016 0.0001 0.0001
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0021 0.0004 0.0004
Mycobacterium tuberculosis Probable oxidoreductase 0.0023 0.0006 0.0132
Echinococcus granulosus rhodopsin orphan GPCR 0.0021 0.0004 0.0004
Trichomonas vaginalis short-chain dehydrogenase, putative 0.0023 0.0006 0.0127
Mycobacterium ulcerans short chain dehydrogenase 0.0023 0.0006 0.0132
Entamoeba histolytica exodeoxyribonuclease III, putative 0.0023 0.0006 0.0082
Plasmodium vivax GTP-binding nuclear protein RAN/TC4, putative 0.0022 0.0006 0.0005
Trichomonas vaginalis glutathione reductase, putative 0.0046 0.0025 0.0527
Trypanosoma cruzi DNA topoisomerase III, putative 0.0265 0.0205 0.0276
Loa Loa (eye worm) AGC/GRK/BARK protein kinase 0.0022 0.0006 0.0005
Brugia malayi acetyltransferase, GNAT family protein 0.0604 0.0485 0.0485
Schistosoma mansoni regulator of G protein signaling 3 rgs3 0.0021 0.0004 0.0004
Mycobacterium ulcerans cytochrome P450 187A5 Cyp187A5 0.0019 0.0003 0.0049
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0018 0.0002 0.0035
Loa Loa (eye worm) DNA topoisomerase I 1.2154 1 1
Mycobacterium ulcerans cytochrome p450 150 cyp150 0.0019 0.0003 0.0049
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.0181 0.0136 0.0136
Trypanosoma brucei Lanosterol 14-alpha demethylase 0.0019 0.0003 0.0003
Trypanosoma brucei DNA polymerase kappa, putative 0.0101 0.0071 0.0095
Giardia lamblia DNA topoisomerase III 0.0257 0.0199 0.4185
Schistosoma mansoni regulator of G protein signaling 0.0021 0.0004 0.0004
Echinococcus multilocularis 7TM GPCR, rhodopsin 0.0021 0.0004 0.0004
Toxoplasma gondii DNA topoisomerase family protein 0.0257 0.0199 0.0199
Plasmodium falciparum ataxin-2 like protein, putative 0.0131 0.0095 0.0095
Entamoeba histolytica heat shock protein 90, putative 0.0095 0.0065 0.1333
Plasmodium vivax DNA repair protein REV1, putative 0.0023 0.0006 0.0006
Echinococcus granulosus rhodopsin orphan GPCR 0.0021 0.0004 0.0004
Mycobacterium tuberculosis Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB 0.0305 0.0239 0.5223
Echinococcus multilocularis axis inhibition protein axin 0.0021 0.0004 0.0004
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0023 0.0006 0.0006
Onchocerca volvulus DNA topoisomerase 2 homolog 0.0074 0.0049 0.0796
Loa Loa (eye worm) hypothetical protein 0.0023 0.0006 0.0006
Mycobacterium tuberculosis Probable short-chain type dehydrogenase/reductase 0.0023 0.0006 0.0132
Loa Loa (eye worm) TYRA-2 protein 0.0021 0.0004 0.0004
Mycobacterium leprae ROBABLE SHORT-CHAIN TYPE DEHYDROGENASE/REDUCTASE 0.0023 0.0006 0.0132
Toxoplasma gondii histone lysine demethylase JMJD6a 0.0043 0.0022 0.0022
Trichomonas vaginalis conserved hypothetical protein 0.0091 0.0062 0.1298
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0023 0.0006 0.0006
Trypanosoma brucei DNA topoisomerase IB, large subunit 0.9025 0.7422 1
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.002 0.0004 0.0004
Mycobacterium tuberculosis Probable chain -fatty-acid-CoA ligase FadD13 (fatty-acyl-CoA synthetase) 0.0029 0.0011 0.0228
Schistosoma mansoni serine/threonine protein kinase 0.0022 0.0006 0.0006
Plasmodium falciparum heat shock protein 90, putative 0.0226 0.0173 0.0173
Onchocerca volvulus 0.0047 0.0026 0.0405
Onchocerca volvulus 0.0021 0.0004 0.004
Loa Loa (eye worm) hypothetical protein 0.0619 0.0498 0.0497
Onchocerca volvulus Serine\/threonine kinase homolog 0.0195 0.0148 0.2491
Plasmodium falciparum DNA topoisomerase 2 0.0074 0.0049 0.0048
Mycobacterium ulcerans citrate (pro-3S)-lyase subunit beta 0.0026 0.0009 0.0177
Mycobacterium tuberculosis Probable cytochrome P450 130 Cyp130 0.0019 0.0003 0.0049
Trichomonas vaginalis PIKK family atypical protein kinase 0.0041 0.0021 0.0438
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0181 0.0136 0.0136
Onchocerca volvulus DNA topoisomerase 2 homolog 0.0074 0.0049 0.0796
Onchocerca volvulus Heat shock protein 75 kDa, mitochondrial homolog 0.0053 0.0031 0.0493
Trypanosoma brucei importin beta-1 subunit, putative 0.003 0.0012 0.0016
Loa Loa (eye worm) hypothetical protein 0.0619 0.0498 0.0497
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0017 0.0001 0.0001
Entamoeba histolytica hypothetical protein 0.0023 0.0006 0.0093
Schistosoma mansoni lamin 0.0056 0.0033 0.0033
Echinococcus multilocularis neuropeptide Y receptor 0.0021 0.0004 0.0004
Trichomonas vaginalis endoplasmin, putative 0.0064 0.004 0.0837
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0023 0.0006 0.0006
Loa Loa (eye worm) jmjC domain-containing protein 0.0061 0.0037 0.0037
Brugia malayi G protein-coupled receptor F59B2.13 0.0021 0.0004 0.0004
Mycobacterium tuberculosis Probable oxidoreductase 0.0339 0.0267 0.5838
Schistosoma mansoni scm-relatedprotein containing 4 mbt domains (sfmbt) 0.0047 0.0026 0.0026
Toxoplasma gondii CMGC kinase, MAPK family (ERK) MAPK-1 0.0051 0.0029 0.0029
Brugia malayi RNA recognition motif domain containing protein 0.0129 0.0093 0.0093
Loa Loa (eye worm) globin family protein 0.0027 0.0009 0.0009
Leishmania major cathepsin L-like protease 0.0069 0.0044 0.0058
Mycobacterium ulcerans short chain dehydrogenase 0.0023 0.0006 0.0132
Mycobacterium ulcerans citrate lyase beta subunit, CitE_2 0.0026 0.0009 0.0177
Schistosoma mansoni cpg binding protein 0.0058 0.0035 0.0035
Toxoplasma gondii ATPase/histidine kinase/DNA gyrase B/HSP90 domain-containing protein 0.0074 0.0049 0.0048
Echinococcus granulosus aldehyde dehydrogenase mitochondrial 0.0191 0.0145 0.0145
Trichomonas vaginalis PIKK family atypical protein kinase 0.0029 0.0011 0.0218
Onchocerca volvulus 0.0019 0.0003 0.0023
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.0181 0.0136 0.0136
Echinococcus granulosus Pleckstrin G protein interacting region 0.0018 0.0002 0.0002
Echinococcus multilocularis neuropeptide receptor 0.0021 0.0004 0.0004
Leishmania major cysteine peptidase A (CPA) 0.0018 0.0002 0.0002
Brugia malayi hypothetical protein 0.0021 0.0004 0.0004
Loa Loa (eye worm) 3-hydroxyacyl-CoA dehydrogenase type II 0.0166 0.0124 0.0124
Echinococcus multilocularis ubiquitin specific protease 41 0.0045 0.0024 0.0024
Loa Loa (eye worm) hypothetical protein 0.0595 0.0478 0.0477
Echinococcus multilocularis jumonji domain containing 1A 0.0043 0.0022 0.0022
Echinococcus multilocularis tachykinin peptides receptor 99D 0.0021 0.0004 0.0004
Trichomonas vaginalis histone acetyltransferase gcn5, putative 0.0017 0.0001 0.0016
Echinococcus granulosus multidrug and toxin extrusion protein 2 0.0069 0.0044 0.0044
Schistosoma mansoni serine/threonine protein kinase 0.0022 0.0006 0.0006
Loa Loa (eye worm) aryl Hydrocarbon receptor Associated protein family member 0.0103 0.0072 0.0072
Loa Loa (eye worm) hypothetical protein 0.0053 0.0031 0.0031
Wolbachia endosymbiont of Brugia malayi topoisomerase IA, TopA 0.0301 0.0235 1
Trichomonas vaginalis PIKK family atypical protein kinase 0.0036 0.0017 0.0346
Brugia malayi Nuclear hormone receptor E75 0.0085 0.0058 0.0058
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0181 0.0136 0.0136
Plasmodium falciparum oxidoreductase, short-chain dehydrogenase family, putative 0.0023 0.0006 0.0006
Toxoplasma gondii histone lysine acetyltransferase GCN5-A 0.0178 0.0134 0.0133
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0023 0.0006 0.0006
Loa Loa (eye worm) hypothetical protein 0.0021 0.0004 0.0004
Echinococcus multilocularis phd:f box containing protein 0.0043 0.0022 0.0022
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.0181 0.0136 0.0136
Echinococcus multilocularis terminal deoxycytidyl transferase rev1 0.0074 0.0048 0.0048
Brugia malayi hypothetical protein 0.0021 0.0004 0.0004
Trypanosoma brucei DNA polymerase kappa, putative 0.0081 0.0054 0.0072
Entamoeba histolytica oxidoreductase, short chain dehydrogenase/reductase family 0.0023 0.0006 0.0093
Trichomonas vaginalis DNA topoisomerase II, putative 0.0074 0.0049 0.1012
Schistosoma mansoni dep domain containing protein 0.0018 0.0002 0.0002
Trichomonas vaginalis hydroxyacyl dehydrogenase, putative 0.0023 0.0006 0.0127
Wolbachia endosymbiont of Brugia malayi heat shock protein 90 0.0083 0.0056 0.2359
Brugia malayi follicle stimulating hormone receptor 0.0021 0.0004 0.0004
Trichomonas vaginalis PIKK family atypical protein kinase 0.0038 0.0019 0.0389
Schistosoma mansoni hypothetical protein 0.0019 0.0003 0.0003
Schistosoma mansoni bromodomain containing protein 0.0018 0.0002 0.0002
Schistosoma mansoni serine/threonine protein kinase 0.0051 0.0029 0.0029
Schistosoma mansoni short chain dehydrogenase 0.0023 0.0006 0.0006
Echinococcus granulosus caspase 8 0.0091 0.0062 0.0062
Leishmania major aldehyde dehydrogenase, mitochondrial precursor 0.0191 0.0145 0.0195
Trichomonas vaginalis heat shock protein, putative 0.0095 0.0065 0.1363
Loa Loa (eye worm) hypothetical protein 0.0021 0.0004 0.0004
Schistosoma mansoni TGF-beta signal transducer Smad2 0.0042 0.0022 0.0022
Loa Loa (eye worm) glycosyl hydrolase family 31 protein 0.0084 0.0057 0.0056
Entamoeba histolytica hypothetical protein 0.0021 0.0004 0.0045
Mycobacterium leprae conserved hypothetical protein 0.0032 0.0014 0.0286
Schistosoma mansoni ataxia telangiectasia mutated (atm)-related 0.0048 0.0027 0.0027
Loa Loa (eye worm) hypothetical protein 0.0085 0.0057 0.0057
Brugia malayi cytoplasmic intermediate filament protein 0.003 0.0012 0.0012
Brugia malayi Nuclear hormone receptor family member nhr-3 0.0181 0.0136 0.0136
Loa Loa (eye worm) hypothetical protein 0.0041 0.0021 0.0021
Mycobacterium ulcerans acyl-CoA synthetase 0.0029 0.0011 0.0228
Trichomonas vaginalis bromodomain-containing protein, putative 0.0178 0.0134 0.2804
Toxoplasma gondii MaoC family domain-containing protein 0.0049 0.0028 0.0027
Leishmania major mitochondrial DNA topoisomerase II 0.0074 0.0049 0.0065
Trypanosoma brucei beta-ketoacyl-ACP reductase 3, putative 0.0023 0.0006 0.0008
Onchocerca volvulus 0.022 0.0168 0.2842
Schistosoma mansoni hypothetical protein 0.1214 0.0988 0.0988
Schistosoma mansoni tar DNA-binding protein 0.0129 0.0093 0.0093
Loa Loa (eye worm) hypothetical protein 0.007 0.0045 0.0044
Trypanosoma cruzi hypothetical protein, conserved 0.0023 0.0006 0.0008
Trypanosoma brucei short-chain dehydrogenase, putative 0.0023 0.0006 0.0008
Entamoeba histolytica Niemann-Pick C1 protein, putative 0.0096 0.0066 0.1359
Trichomonas vaginalis CAMK family protein kinase 0.0195 0.0148 0.3102
Brugia malayi Tyrosyl-DNA phosphodiesterase family protein 0.0068 0.0043 0.0043
Brugia malayi Smad1 0.0042 0.0022 0.0022
Brugia malayi nuclear receptor subfamily 1, group D, member 1, putative 0.0085 0.0058 0.0058
Brugia malayi hypothetical protein 0.0085 0.0058 0.0058
Brugia malayi steroid hormone receptor 0.0181 0.0136 0.0136
Loa Loa (eye worm) hypothetical protein 0.0021 0.0004 0.0004
Schistosoma mansoni aminoadipate-semialdehyde dehydrogenase 0.0595 0.0478 0.0478
Loa Loa (eye worm) cytochrome P450 family protein 0.0046 0.0025 0.0025
Loa Loa (eye worm) hypothetical protein 0.0021 0.0004 0.0004
Trypanosoma cruzi Vps23 core domain containing protein, putative 0.0022 0.0006 0.0007
Schistosoma mansoni neuropeptide receptor 0.0021 0.0004 0.0004
Echinococcus granulosus DNA topoisomerase 1 1.2154 1 1
Brugia malayi Muscleblind-like protein 0.0619 0.0498 0.0498
Echinococcus multilocularis DNA topoisomerase 2 alpha 0.0074 0.0049 0.0049
Trichomonas vaginalis PIKK family atypical protein kinase 0.0029 0.0011 0.0218
Leishmania major heat shock protein 83-1 0.0095 0.0065 0.0087
Loa Loa (eye worm) gonadotropin-releasing hormone receptor 2 0.0021 0.0004 0.0004
Leishmania major glycosyl hydrolase-like protein 0.0031 0.0013 0.0017
Loa Loa (eye worm) hypothetical protein 0.0038 0.0019 0.0019
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0021 0.0004 0.0004
Onchocerca volvulus 0.0021 0.0004 0.004
Mycobacterium tuberculosis Probable cytochrome P450 140 Cyp140 0.0019 0.0003 0.0049
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0018 0.0002 0.0035
Loa Loa (eye worm) hypothetical protein 0.0021 0.0004 0.0004
Loa Loa (eye worm) transcription factor SMAD2 0.0616 0.0494 0.0494
Schistosoma mansoni amine GPCR 0.0021 0.0004 0.0004
Trypanosoma cruzi cysteine peptidase, putative 0.0069 0.0044 0.0058
Schistosoma mansoni patched 1 0.0041 0.0021 0.0021
Loa Loa (eye worm) isocitrate dehydrogenase 0.0097 0.0067 0.0067
Trypanosoma brucei unspecified product 0.0051 0.0029 0.0039
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0045 0.0024 0.0497
Mycobacterium tuberculosis Possible short-chain dehydrogenase EphD 0.0023 0.0006 0.0132
Brugia malayi hypothetical protein 0.0021 0.0004 0.0004
Echinococcus granulosus tm gpcr rhodopsin 0.0021 0.0004 0.0004
Schistosoma mansoni biogenic amine receptor 0.0021 0.0004 0.0004
Toxoplasma gondii PHD-finger domain-containing protein 0.0029 0.0011 0.0011
Trichomonas vaginalis adenylate and guanylate cyclases, putative 0.0085 0.0057 0.1195
Loa Loa (eye worm) hypothetical protein 0.0021 0.0004 0.0004
Trypanosoma brucei importin beta-1 subunit, putative 0.003 0.0012 0.0016
Onchocerca volvulus 0.0027 0.0009 0.0123
Schistosoma mansoni DNA topoisomerase type I 1.2154 1 1
Mycobacterium ulcerans hypothetical protein 0.0032 0.0013 0.0284
Mycobacterium ulcerans cytochrome P450 143A4 Cyp143A4 0.0019 0.0003 0.0049
Echinococcus multilocularis neuropeptides capa receptor 0.0021 0.0004 0.0004
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0021 0.0005 0.0098
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0045 0.0024 0.0032
Mycobacterium ulcerans DNA polymerase IV 0.0101 0.0071 0.1543
Trypanosoma brucei PAB1-binding protein , putative 0.0131 0.0095 0.0127
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0064 0.004 0.004
Loa Loa (eye worm) TOPoisomerase family member 0.0074 0.0049 0.0048
Schistosoma mansoni tar DNA-binding protein 0.0129 0.0093 0.0093
Loa Loa (eye worm) hypothetical protein 0.0021 0.0004 0.0004
Mycobacterium ulcerans fructose-bisphosphate aldolase 0.0289 0.0226 0.4936
Brugia malayi RNA, U transporter 1 0.0086 0.0058 0.0058
Schistosoma mansoni alpha-galactosidase/alpha-n-acetylgalactosaminidase 0.014 0.0103 0.0103
Mycobacterium ulcerans aldehyde dehydrogenase 0.0191 0.0145 0.3164
Onchocerca volvulus 0.0021 0.0004 0.004
Plasmodium falciparum DNA gyrase subunit B 0.0074 0.0049 0.0048
Trypanosoma cruzi Phosphatidylinositol 3-kinase tor2 0.0048 0.0027 0.0036
Trypanosoma cruzi glycosyl hydrolase-like protein, putative 0.0031 0.0013 0.0017
Leishmania major adenylate cyclase-like protein 0.0027 0.0009 0.0012
Loa Loa (eye worm) heat shock protein 90 0.0095 0.0065 0.0065
Mycobacterium tuberculosis Conserved hypothetical protein 0.0032 0.0014 0.0286
Brugia malayi hypothetical protein 0.0066 0.0042 0.0042
Mycobacterium tuberculosis Possible iron-regulated short-chain dehydrogenase/reductase 0.0023 0.0006 0.0132
Schistosoma mansoni carbonyl reductase 0.0023 0.0006 0.0006
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0021 0.0004 0.0004
Loa Loa (eye worm) MH1 domain-containing protein 0.0019 0.0003 0.0003
Mycobacterium ulcerans cytochrome P450 185A4 Cyp185A4 0.0046 0.0025 0.0544
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0023 0.0006 0.0006
Brugia malayi aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase 0.0595 0.0478 0.0478
Echinococcus granulosus Smad4 0.0042 0.0022 0.0022
Trypanosoma brucei DNA polymerase kappa, putative 0.0058 0.0035 0.0047
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0069 0.0044 0.0058
Schistosoma mansoni cpg binding protein 0.0061 0.0038 0.0038
Trypanosoma cruzi DNA polymerase kappa, putative 0.0101 0.0071 0.0095
Brugia malayi Thioredoxin reductase 0.0134 0.0098 0.0098
Mycobacterium ulcerans acyl-CoA synthetase 0.0029 0.0011 0.0228
Mycobacterium ulcerans cytochrome P450 150A6 Cyp150A6 0.0019 0.0003 0.0049
Trypanosoma cruzi cysteine peptidase, putative 0.0069 0.0044 0.0058
Trichomonas vaginalis CAMK family protein kinase 0.0097 0.0067 0.1404
Trypanosoma brucei DNA polymerase kappa, putative 0.0058 0.0035 0.0047
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0181 0.0136 0.0136
Echinococcus granulosus tm gpcr rhodopsin 0.0021 0.0004 0.0004
Loa Loa (eye worm) ABC transporter 0.0017 0.0001 0.0001
Loa Loa (eye worm) hypothetical protein 0.0027 0.001 0.0009
Mycobacterium ulcerans cytochrome P450 108B4 Cyp108B4 0.0019 0.0003 0.0049
Echinococcus multilocularis endonuclease exonuclease phosphatase 0.0188 0.0142 0.0142
Toxoplasma gondii BRCA1 C Terminus (BRCT) domain-containing protein 0.003 0.0012 0.0011
Trichomonas vaginalis PIKK family atypical protein kinase 0.0038 0.0019 0.0389
Mycobacterium ulcerans acyl-CoA synthetase 0.0029 0.0011 0.0228
Plasmodium vivax DNA topoisomerase 3, putative 0.0257 0.0199 0.0199
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0046 0.0025 0.0034
Plasmodium falciparum isocitrate dehydrogenase [NADP], mitochondrial 0.0097 0.0067 0.0067
Brugia malayi Nuclear hormone receptor-like 1 0.0096 0.0066 0.0066
Trypanosoma cruzi hypothetical protein, conserved 0.0084 0.0057 0.0076
Echinococcus granulosus carbonyl reductase 1 0.0023 0.0006 0.0006
Brugia malayi Globin family protein 0.0027 0.0009 0.0009
Brugia malayi ecdysone receptor 0.0085 0.0058 0.0058
Mycobacterium tuberculosis Probable short-chain type dehydrogenase/reductase 0.0023 0.0006 0.0132
Trypanosoma cruzi flap endonuclease-1 (FEN-1), putative 0.0027 0.001 0.0013
Echinococcus granulosus Basic leucine zipper bZIP transcription factor 0.0084 0.0056 0.0056
Trypanosoma brucei 3-ketoacyl-CoA reductase, putative 0.0023 0.0006 0.0008
Mycobacterium ulcerans hypothetical protein 0.0032 0.0014 0.0286
Echinococcus multilocularis regulator of G protein signaling 3 0.0021 0.0004 0.0004
Schistosoma mansoni single-minded 0.0305 0.0238 0.0238
Trypanosoma brucei inositol-1(or 4)-monophosphatase 1, putative 0.0117 0.0083 0.0112
Onchocerca volvulus 0.0021 0.0004 0.004
Mycobacterium ulcerans short-chain dehydrogenase 0.0023 0.0006 0.0132
Echinococcus granulosus allatostatin A receptor 0.0021 0.0004 0.0004
Trypanosoma brucei phosphatidylinositol 3-kinase tor, putative 0.0023 0.0006 0.0008
Echinococcus granulosus carbonyl reductase 1 0.0023 0.0006 0.0006
Echinococcus granulosus transient receptor potential ion channel A 0.0188 0.0142 0.0142
Leishmania major heat shock protein 83-1 0.0095 0.0065 0.0087
Trypanosoma brucei metacaspase MCA3 0.0091 0.0062 0.0083
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0023 0.0006 0.0006
Schistosoma mansoni hypothetical protein 0.0085 0.0057 0.0057
Brugia malayi hypothetical protein 0.0021 0.0004 0.0004
Echinococcus granulosus single minded 2 0.022 0.0168 0.0168
Brugia malayi ImpB/MucB/SamB family protein 0.0127 0.0092 0.0092
Loa Loa (eye worm) glutathione reductase 0.0134 0.0098 0.0097
Trypanosoma brucei heat shock protein, putative 0.0095 0.0065 0.0087
Leishmania major 2-oxoglutarate dehydrogenase, e3 component, lipoamidedehydrogenase-like protein 0.0046 0.0025 0.0034
Onchocerca volvulus 0.0032 0.0013 0.0196
Leishmania major cathepsin L-like protease 0.0069 0.0044 0.0058
Mycobacterium ulcerans cytochrome P450 140A5 Cyp140A5 0.0019 0.0003 0.0049
Echinococcus granulosus neutral alpha glucosidase AB 0.0084 0.0057 0.0057
Brugia malayi G-protein-linked acetylcholine receptor protein 2, putative 0.0021 0.0004 0.0004
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.0181 0.0136 0.0136
Entamoeba histolytica hypothetical protein 0.033 0.0259 0.5426
Onchocerca volvulus Huntingtin homolog 0.0383 0.0303 0.5133
Trichomonas vaginalis glucosylceramidase, putative 0.0278 0.0216 0.4537
Echinococcus granulosus segment polarity protein dishevelled 0.0018 0.0002 0.0002
Schistosoma mansoni jun-related protein 0.0068 0.0044 0.0044
Trypanosoma cruzi tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0068 0.0043 0.0058
Trichomonas vaginalis heat shock protein, putative 0.0083 0.0056 0.1166
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0064 0.004 0.004
Brugia malayi photoreceptor-specific nuclear receptor 0.1162 0.0945 0.0945
Trypanosoma cruzi heat shock protein 90, putative 0.0046 0.0025 0.0034
Plasmodium falciparum metacaspase-like protein 0.0091 0.0062 0.0062
Loa Loa (eye worm) hypothetical protein 0.0026 0.0009 0.0009
Brugia malayi Cathepsin L-like precursor 0.0018 0.0002 0.0002
Schistosoma mansoni biogenic amine receptor 0.0021 0.0004 0.0004
Brugia malayi hypothetical protein 0.0027 0.0009 0.0009
Trypanosoma brucei membrane transporter protein, putative 0.0069 0.0044 0.0058
Schistosoma mansoni alpha-galactosidase/alpha-n-acetylgalactosaminidase 0.021 0.016 0.016
Trypanosoma brucei DNA topoisomerase ii 0.0074 0.0049 0.0065
Mycobacterium ulcerans cytochrome P450 136A2 Cyp136A2 0.0019 0.0003 0.0049
Echinococcus multilocularis carbonyl reductase 1 0.0023 0.0006 0.0006
Schistosoma mansoni caspase-3 (C14 family) 0.024 0.0185 0.0185
Trypanosoma brucei DNA topoisomerase IA, putative 0.0257 0.0199 0.0268
Loa Loa (eye worm) hypothetical protein 0.0027 0.0009 0.0009
Echinococcus granulosus cpg binding protein 0.0061 0.0038 0.0038
Loa Loa (eye worm) cytochrome P450 0.0019 0.0003 0.0003
Loa Loa (eye worm) hypothetical protein 0.0085 0.0058 0.0058
Schistosoma mansoni steroid dehydrogenase 0.0023 0.0006 0.0006
Echinococcus granulosus G protein coupled receptor 139 0.0021 0.0004 0.0004
Onchocerca volvulus Protein ultraspiracle homolog 0.0181 0.0136 0.2296
Mycobacterium ulcerans UDP-galactopyranose mutase Glf 0.057 0.0457 1
Loa Loa (eye worm) hypothetical protein 0.0021 0.0004 0.0004
Echinococcus multilocularis lysosomal alpha glucosidase 0.0319 0.025 0.025
Echinococcus multilocularis ferritin 0.0035 0.0016 0.0016
Echinococcus granulosus FTZ F1 alpha 0.0181 0.0136 0.0136
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0021 0.0004 0.0004
Echinococcus granulosus dna polymerase eta 0.0127 0.0092 0.0092
Trypanosoma cruzi ATP-binding cassette protein, putative 0.002 0.0004 0.0004
Echinococcus granulosus dro:myosuppressin receptor 0.0021 0.0004 0.0004
Loa Loa (eye worm) tyrosyl-DNA phosphodiesterase 0.0068 0.0043 0.0043
Echinococcus multilocularis tar DNA binding protein 0.0129 0.0093 0.0093
Echinococcus granulosus rhodopsin orphan GPCR 0.0021 0.0004 0.0004
Mycobacterium tuberculosis Conserved hypothetical protein 0.0074 0.0048 0.1049
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD2 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0029 0.0011 0.0228
Echinococcus granulosus lamin dm0 0.0056 0.0033 0.0033
Schistosoma mansoni short chain dehydrogenase 0.0023 0.0006 0.0006
Mycobacterium tuberculosis Probable soluble pyridine nucleotide transhydrogenase SthA (STH) (NAD(P)(+) transhydrogenase [B-specific]) (nicotinamide nucleot 0.0046 0.0025 0.0549
Loa Loa (eye worm) hypothetical protein 0.0021 0.0004 0.0004
Leishmania major quinonoid dihydropteridine reductase 0.0023 0.0006 0.0008
Echinococcus granulosus lamin 0.0056 0.0033 0.0033
Mycobacterium tuberculosis Probable dehydrogenase/reductase 0.0023 0.0006 0.0132
Brugia malayi hypothetical protein 0.0018 0.0002 0.0002
Mycobacterium tuberculosis Conserved protein 0.0032 0.0014 0.0286
Trichomonas vaginalis conserved hypothetical protein 0.0021 0.0004 0.008
Loa Loa (eye worm) acetyltransferase 0.0604 0.0485 0.0485
Echinococcus multilocularis lysosomal alpha glucosidase 0.0319 0.025 0.025
Loa Loa (eye worm) hypothetical protein 0.0021 0.0004 0.0004
Mycobacterium tuberculosis Probable citrate (pro-3S)-lyase (beta subunit) CitE (citrase) (citratase) (citritase) (citridesmolase) (citrase aldolase) 0.0026 0.0009 0.0177
Trichomonas vaginalis short-chain dehydrogenases/reductase, putative 0.0023 0.0006 0.0127
Brugia malayi Glycosyl hydrolases family 31 protein 0.0031 0.0013 0.0013
Schistosoma mansoni myosin xvIII 0.0021 0.0004 0.0004
Echinococcus granulosus Aryl hydrocarbon receptor nuclear 0.0085 0.0057 0.0057
Mycobacterium tuberculosis Possible cytochrome P450 135A1 Cyp135A1 0.0019 0.0003 0.0049
Schistosoma mansoni neuropeptide receptor 0.0021 0.0004 0.0004
Giardia lamblia Histone acetyltransferase GCN5 0.0163 0.0121 0.2547
Trypanosoma cruzi importin beta-1 subunit, putative 0.0025 0.0008 0.001
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0091 0.0062 0.1298
Trichomonas vaginalis PIKK family atypical protein kinase 0.0029 0.0011 0.0223
Mycobacterium ulcerans cytochrome P450 188A3 Cyp188A3 0.0019 0.0003 0.0049
Entamoeba histolytica Acid sphingomyelinase-like phosphodiesterase, putative 0.0169 0.0127 0.2637
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0091 0.0062 0.1298
Trichomonas vaginalis short-chain dehydrogenase, putative 0.0023 0.0006 0.0127
Leishmania major hypothetical protein, conserved 0.0023 0.0006 0.0008
Mycobacterium leprae Possible short-chain dehydrogenase EphD 0.0023 0.0006 0.0132
Leishmania major myo-inositol-1(or 4)-monophosphatase 1, putative 0.0117 0.0083 0.0112
Mycobacterium ulcerans phosphopantetheinyl transferase, PptII 0.0167 0.0125 0.2733
Echinococcus multilocularis Jumonji, AT rich interactive domain 1B 0.0046 0.0025 0.0025
Loa Loa (eye worm) hypothetical protein 0.0023 0.0006 0.0006
Schistosoma mansoni tar DNA-binding protein 0.0129 0.0093 0.0093
Echinococcus multilocularis rhodopsin orphan GPCR 0.0021 0.0004 0.0004
Echinococcus multilocularis TGF beta signal transducer SmadC 0.0042 0.0022 0.0022
Echinococcus multilocularis aryl hydrocarbon receptor 0.0103 0.0072 0.0072
Plasmodium vivax SET domain protein, putative 0.0064 0.004 0.004
Brugia malayi nuclear hormone receptor 0.0085 0.0058 0.0058
Mycobacterium tuberculosis Possible DNA-damage-inducible protein P DinP (DNA polymerase V) (pol IV 2) (DNA nucleotidyltransferase (DNA-directed)) 0.0081 0.0054 0.1171
Mycobacterium ulcerans hypothetical protein 0.0032 0.0014 0.0286
Mycobacterium tuberculosis Conserved protein 0.0026 0.0009 0.0177
Loa Loa (eye worm) hypothetical protein 0.0019 0.0003 0.0003
Leishmania major heat shock protein 83-1 0.0095 0.0065 0.0087
Echinococcus multilocularis isocitrate dehydrogenase 2 (NADP+) 0.0097 0.0067 0.0067
Trichomonas vaginalis adenylate cyclase, type VII, putative 0.0085 0.0057 0.1195
Echinococcus granulosus thioredoxin glutathione reductase 0.0134 0.0098 0.0098
Leishmania major DNA polymerase kappa, putative,DNA polymerase IV, putative 0.0081 0.0054 0.0072
Trichomonas vaginalis PIKK family atypical protein kinase 0.0038 0.0019 0.0389
Giardia lamblia Heat shock protein HSP 90-alpha 0.0079 0.0052 0.1086
Wolbachia endosymbiont of Brugia malayi DNA gyrase, topoisomerase II, B subunit, GyrB 0.0074 0.0049 0.2048
Trichomonas vaginalis glucosylceramidase, putative 0.0278 0.0216 0.4537
Giardia lamblia Hypothetical protein 0.0023 0.0006 0.0127
Echinococcus multilocularis transfer RNA-Lys 0.022 0.0168 0.0168
Echinococcus multilocularis aldehyde dehydrogenase, mitochondrial 0.0191 0.0145 0.0145
Onchocerca volvulus 0.0018 0.0002 0.0003
Echinococcus multilocularis segment polarity protein dishevelled 0.0018 0.0002 0.0002
Schistosoma mansoni biogenic amine receptor 0.0021 0.0004 0.0004
Trypanosoma cruzi hypothetical protein, conserved 0.0023 0.0006 0.0008
Brugia malayi hypothetical protein 0.0383 0.0303 0.0303
Leishmania major DNA damage repair protein, putative 0.0023 0.0006 0.0008
Trypanosoma brucei isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0097 0.0067 0.009
Schistosoma mansoni inositol monophosphatase 0.0117 0.0083 0.0083
Plasmodium falciparum holo-[acyl-carrier-protein] synthase, putative 0.0167 0.0125 0.0125
Brugia malayi Protein kinase domain containing protein 0.0019 0.0003 0.0003
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0018 0.0002 0.0035
Brugia malayi ORL1-like opioid receptor 0.0021 0.0004 0.0004
Loa Loa (eye worm) hypothetical protein 0.0021 0.0004 0.0004
Trichomonas vaginalis alpha-galactosidase/alpha-N-acetylgalactosaminidase, putative 0.014 0.0103 0.2152
Mycobacterium tuberculosis Probable cytochrome P450 monooxygenase 142 Cyp142 0.0019 0.0003 0.0049
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.0181 0.0136 0.0136
Schistosoma mansoni smad1 5 8 and 0.0042 0.0022 0.0022
Mycobacterium ulcerans cytochrome P450 126A3 Cyp126A3 0.0019 0.0003 0.0049
Echinococcus multilocularis caspase 2 0.0175 0.0132 0.0132
Loa Loa (eye worm) hypothetical protein 0.0021 0.0004 0.0004
Loa Loa (eye worm) hypothetical protein 0.0043 0.0022 0.0022
Echinococcus granulosus mothers against decapentaplegic 2 0.0019 0.0003 0.0003
Loa Loa (eye worm) phosphatidylinositol 3 0.0016 0.0001 0.0001
Schistosoma mansoni jumonji domain containing protein 0.0043 0.0022 0.0022
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.0181 0.0136 0.0136
Echinococcus granulosus hypothetical protein 0.0023 0.0006 0.0006
Trichomonas vaginalis PIKK family atypical protein kinase 0.0036 0.0017 0.0346
Echinococcus granulosus endoplasmin 0.0083 0.0056 0.0056
Trichomonas vaginalis DNA polymerase IV / kappa, putative 0.0101 0.0071 0.1483
Brugia malayi larval opioid receptor 0.0021 0.0004 0.0004
Echinococcus multilocularis pyroglutamylated rfamide peptide receptor 0.0021 0.0004 0.0004
Mycobacterium ulcerans transmembrane ABC transporter ATP-binding protein 0.002 0.0004 0.0071
Echinococcus multilocularis transient receptor potential ion channel A 0.0188 0.0142 0.0142
Mycobacterium ulcerans oxidoreductase 0.0023 0.0006 0.0132
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0064 0.004 0.004
Onchocerca volvulus 0.0023 0.0006 0.0078
Brugia malayi neuropeptide F receptor 0.0021 0.0004 0.0004
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0097 0.0067 0.0067
Trichomonas vaginalis CMGC family protein kinase 0.0051 0.0029 0.0611
Toxoplasma gondii ImpB/MucB/SamB family protein 0.0023 0.0006 0.0006
Brugia malayi nuclear receptor NHR-67 0.0085 0.0058 0.0058
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0018 0.0002 0.0035
Loa Loa (eye worm) hypothetical protein 0.0051 0.0029 0.0029
Schistosoma mansoni nuclear hormone receptor superfamily protein-related 0.0085 0.0058 0.0058
Echinococcus granulosus retinol dehydrogenase 11 0.0023 0.0006 0.0006
Mycobacterium tuberculosis Possible cytochrome P450 135B1 Cyp135B1 0.0019 0.0003 0.0049
Echinococcus granulosus expressed protein 0.0401 0.0318 0.0318
Echinococcus multilocularis tyrosyl DNA phosphodiesterase 1 0.0068 0.0043 0.0043
Entamoeba histolytica ABC transporter, putative 0.002 0.0004 0.0033
Leishmania major heat shock protein 83-1 0.0095 0.0065 0.0087
Echinococcus multilocularis atpase aaa+ type core atpase aaa type core 0.3363 0.2758 0.2758
Schistosoma mansoni 3-keto-dihydrosphingosine reductase 0.0023 0.0006 0.0006
Entamoeba histolytica 3-ketodihydrosphingosine reductase protein, putative 0.0023 0.0006 0.0093
Schistosoma mansoni ap endonuclease 0.0023 0.0006 0.0006
Trypanosoma brucei mitogen activated protein kinase 4, putative 0.0051 0.0029 0.0039
Mycobacterium ulcerans short chain dehydrogenase 0.0023 0.0006 0.0132
Plasmodium vivax dihydrolipoyl dehydrogenase, apicoplast, putative 0.0046 0.0025 0.0025
Mycobacterium tuberculosis Probable short-chain type dehydrogenase/reductase 0.0189 0.0143 0.3122
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0018 0.0002 0.0035
Toxoplasma gondii sterol carrier protein-2 HAD-2SCP-2 0.0093 0.0064 0.0063
Loa Loa (eye worm) hypothetical protein 0.0175 0.0132 0.0132
Trichomonas vaginalis PIKK family atypical protein kinase 0.0036 0.0017 0.0346
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0091 0.0062 0.1298
Onchocerca volvulus 0.0021 0.0004 0.004
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0055 0.0033 0.0033
Loa Loa (eye worm) G-protein coupled receptor 0.0021 0.0004 0.0004
Schistosoma mansoni fyve finger-containing phosphoinositide kinase fyv1 0.0018 0.0002 0.0002
Schistosoma mansoni prokaryotic DNA topoisomerase 0.0308 0.0241 0.0241
Trypanosoma cruzi Lanosterol 14-alpha demethylase 0.0019 0.0003 0.0003
Echinococcus multilocularis rhodopsin orphan GPCR 0.0021 0.0004 0.0004
Schistosoma mansoni regulator of G protein signaling 0.0021 0.0004 0.0004
Schistosoma mansoni transient receptor potential channel 0.0128 0.0093 0.0093
Trypanosoma brucei cytochrome P450, putative 0.0046 0.0025 0.0033
Plasmodium vivax JmjC domain containing protein 0.0043 0.0022 0.0022
Echinococcus multilocularis mothers against decapentaplegic 6 0.0019 0.0003 0.0003
Brugia malayi Bromodomain containing protein 0.0044 0.0024 0.0024
Mycobacterium tuberculosis Possible oxidoreductase 0.0023 0.0006 0.0132
Leishmania major oxidoreductase-like protein 0.0023 0.0006 0.0008
Schistosoma mansoni apoferritin-2 0.0035 0.0016 0.0016
Entamoeba histolytica acetyltransferase, GNAT family 0.0163 0.0121 0.2521
Trypanosoma cruzi quinonoid dihydropteridine reductase, putative 0.0023 0.0006 0.0008
Leishmania major ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative 0.0045 0.0024 0.0032
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0018 0.0002 0.0035
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0069 0.0044 0.0058
Mycobacterium tuberculosis Probable cytochrome P450 137 Cyp137 0.0019 0.0003 0.0049
Loa Loa (eye worm) hypothetical protein 0.0021 0.0004 0.0004
Brugia malayi hypothetical protein 0.0131 0.0095 0.0095
Trypanosoma cruzi JmjC domain, hydroxylase, putative 0.0043 0.0022 0.003
Trypanosoma brucei ABC transporter, putative 0.002 0.0004 0.0004
Brugia malayi dihydrolipoyl dehydrogenase, mitochondrial precursor, putative 0.0046 0.0025 0.0025
Toxoplasma gondii cytochrome p450 superfamily protein 0.0019 0.0003 0.0002
Mycobacterium ulcerans short chain dehydrogenase 0.0023 0.0006 0.0132
Brugia malayi N-terminal motif family protein 0.0361 0.0285 0.0285
Echinococcus granulosus dna polymerase kappa 0.0101 0.0071 0.0071
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0018 0.0002 0.0035
Echinococcus multilocularis 0.0413 0.0328 0.0328
Echinococcus multilocularis protein patched 0.0041 0.0021 0.0021
Trypanosoma cruzi target of rapamycin kinase 3 0.0038 0.0019 0.0025
Schistosoma mansoni alpha-galactosidase/alpha-n-acetylgalactosaminidase 0.021 0.016 0.016
Echinococcus multilocularis fmrfamide receptor 0.0021 0.0004 0.0004
Echinococcus granulosus carbonyl reductase 1 0.0023 0.0006 0.0006
Echinococcus multilocularis heat shock protein 75 kDa, mitochondrial 0.0053 0.0031 0.0031
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0023 0.0006 0.0132
Schistosoma mansoni short chain dehydrogenase 0.0023 0.0006 0.0006
Loa Loa (eye worm) hypothetical protein 0.0096 0.0066 0.0066
Loa Loa (eye worm) pigment dispersing factor receptor c 0.006 0.0037 0.0037
Trypanosoma cruzi 3-ketoacyl-CoA reductase, putative 0.0023 0.0006 0.0008
Schistosoma mansoni steroid dehydrogenase 0.0023 0.0006 0.0006
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0048 0.0027 0.0027
Echinococcus multilocularis beta adrenergic receptor kinase 0.0022 0.0006 0.0006
Mycobacterium ulcerans hypothetical protein 0.0029 0.0011 0.0228
Leishmania major 2,4-dihydroxyhept-2-ene-1,7-dioic acid aldolase, putative 0.0026 0.0009 0.0011
Echinococcus granulosus X box binding protein 1 0.0348 0.0274 0.0274
Echinococcus granulosus serotonin receptor 0.0021 0.0004 0.0004
Echinococcus multilocularis cysteine protease 0.0018 0.0002 0.0002
Loa Loa (eye worm) DNA topoisomerase III beta-1 0.0134 0.0098 0.0098
Onchocerca volvulus Huntingtin homolog 0.0383 0.0303 0.5133
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0064 0.004 0.004
Echinococcus granulosus short transient receptor potential channel 6 0.0128 0.0093 0.0093
Schistosoma mansoni phosphatidylserine receptor 0.0043 0.0022 0.0022
Trichomonas vaginalis heat shock protein, putative 0.0083 0.0056 0.1166
Brugia malayi neuropeptide F receptor 0.0021 0.0004 0.0004
Schistosoma mansoni aryl hydrocarbon receptor nuclear translocator homolog (darnt) 0.0018 0.0002 0.0002
Mycobacterium ulcerans cytochrome P450 191A3 Cyp191A3 0.0019 0.0003 0.0049
Trichomonas vaginalis CMGC family protein kinase 0.0051 0.0029 0.0611
Trichomonas vaginalis short-chain dehydrogenase, putative 0.0023 0.0006 0.0127
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0045 0.0024 0.0032
Echinococcus granulosus tar DNA binding protein 0.0129 0.0093 0.0093
Loa Loa (eye worm) hypothetical protein 0.0018 0.0002 0.0002
Echinococcus multilocularis DNA topoisomerase 1 1.2154 1 1
Loa Loa (eye worm) SCP-2 sterol transfer family protein 0.0032 0.0013 0.0013
Trypanosoma brucei JmjC domain, hydroxylase, putative 0.0043 0.0022 0.003
Echinococcus multilocularis rho GTPase activating protein 20 0.0265 0.0205 0.0205
Plasmodium falciparum DNA repair protein REV1, putative 0.0023 0.0006 0.0006
Trichomonas vaginalis glucosylceramidase, putative 0.0278 0.0216 0.4537
Loa Loa (eye worm) hypothetical protein 0.0021 0.0005 0.0005
Echinococcus granulosus alpha 1A adrenergic receptor 0.0021 0.0004 0.0004
Brugia malayi Pre-SET motif family protein 0.0439 0.0349 0.0349
Toxoplasma gondii 3-ketoacyl-CoA reductase, putative 0.0023 0.0006 0.0006
Onchocerca volvulus 0.0056 0.0033 0.0537
Brugia malayi CHE-14 protein 0.0041 0.0021 0.0021
Echinococcus multilocularis zinc finger protein 0.0018 0.0002 0.0002
Schistosoma mansoni lamin 0.0056 0.0033 0.0033
Echinococcus granulosus heat shock protein heat shock protein 90 alpha 0.0079 0.0052 0.0052
Brugia malayi hypothetical protein 0.0021 0.0004 0.0004
Trichomonas vaginalis CAMK family protein kinase 0.0195 0.0148 0.3102
Brugia malayi Endoplasmin precursor 0.0095 0.0065 0.0065
Mycobacterium tuberculosis Probable short-chain type dehydrogenase/reductase 0.0061 0.0038 0.0814
Leishmania major protein kinase, putative,polo-like protein kinase, putative 0.0195 0.0148 0.0199
Echinococcus granulosus A kinase anchor protein 10 mitochondrial 0.0021 0.0004 0.0004
Trichomonas vaginalis glucosylceramidase, putative 0.0182 0.0137 0.2881
Mycobacterium tuberculosis Probable dehydrogenase. Possible 2-enoyl acyl-CoA hydratase. 0.0081 0.0054 0.1173
Trypanosoma brucei heat shock protein 90, putative 0.0095 0.0065 0.0087
Trypanosoma cruzi hypothetical protein, conserved 0.0023 0.0006 0.0008
Entamoeba histolytica hypothetical protein 0.033 0.0259 0.5426
Leishmania major quinonoid dihydropteridine reductase 0.0023 0.0006 0.0008
Echinococcus granulosus oxidoreductase 0.0023 0.0006 0.0006
Loa Loa (eye worm) dehydrogenase 0.0023 0.0006 0.0006
Schistosoma mansoni jumonji/arid domain-containing protein 0.0164 0.0122 0.0122
Loa Loa (eye worm) PLK/PLK1 protein kinase 0.0195 0.0148 0.0148
Echinococcus multilocularis steroid dehydrogenase 0.0023 0.0006 0.0006
Brugia malayi Protein kinase domain containing protein 0.0181 0.0136 0.0136
Echinococcus granulosus Niemann Pick C1 protein 0.0137 0.01 0.01
Loa Loa (eye worm) hypothetical protein 0.0021 0.0005 0.0005
Trichomonas vaginalis prokaryotic DNA topoisomerase, putative 0.0257 0.0199 0.4185
Plasmodium vivax acyl-CoA synthetase, putative 0.0021 0.0005 0.0004
Trypanosoma brucei hypothetical protein, conserved 0.0224 0.0172 0.0231
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0085 0.0058 0.0951
Schistosoma mansoni 3-hydroxyacyl-CoA dehydrogenase 0.0189 0.0143 0.0143
Mycobacterium ulcerans short chain dehydrogenase 0.0023 0.0006 0.0132
Loa Loa (eye worm) hypothetical protein 0.1022 0.0829 0.0829
Echinococcus granulosus heat shock protein 90 0.0079 0.0052 0.0052
Loa Loa (eye worm) TAR-binding protein 0.0129 0.0093 0.0093
Mycobacterium tuberculosis (3R)-hydroxyacyl-ACP dehydratase subunit HadC 0.0032 0.0014 0.0286
Mycobacterium ulcerans cytochrome P450 123A3 Cyp123A3 0.0019 0.0003 0.0049
Trichomonas vaginalis alpha-glucosidase, putative 0.0084 0.0057 0.1181
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0019 0.0003 0.0003
Mycobacterium ulcerans aldehyde dehydrogenase 0.0191 0.0145 0.3164
Schistosoma mansoni short chain dehydrogenase 0.0023 0.0006 0.0006
Echinococcus granulosus phd:f box containing protein 0.0043 0.0022 0.0022
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0084 0.0057 0.1181
Leishmania major quinonoid dihydropteridine reductase 0.0023 0.0006 0.0008
Schistosoma mansoni short chain dehydrogenase 0.0023 0.0006 0.0006
Schistosoma mansoni DNA polymerase IV / kappa 0.0023 0.0006 0.0006
Trichomonas vaginalis conserved hypothetical protein 0.0091 0.0062 0.1298
Echinococcus multilocularis neuropeptide Y receptor 0.0021 0.0004 0.0004
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0048 0.0027 0.0027
Mycobacterium leprae PROBABLE BACTERIOFERRITIN BFRA 0.0035 0.0016 0.0338
Echinococcus multilocularis conserved hypothetical protein 0.0023 0.0006 0.0006
Trichomonas vaginalis PIKK family atypical protein kinase 0.0016 0.0001 0.0004
Schistosoma mansoni neuropeptide F-like receptor 0.0021 0.0004 0.0004
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.0022 0.0006 0.0007
Trypanosoma brucei beta-ketoacyl-ACP reductase 2 0.0023 0.0006 0.0008
Mycobacterium tuberculosis Probable short chain alcohol dehydrogenase/reductase 0.0023 0.0006 0.0132
Leishmania major lipophosphoglycan biosynthetic protein, putative,heat shock protein 90, putative,glucose regulated protein 94, putative 0.0083 0.0056 0.0075
Plasmodium falciparum heat shock protein 90, putative 0.0048 0.0027 0.0027
Echinococcus multilocularis orexin receptor type 2 0.0021 0.0004 0.0004
Loa Loa (eye worm) hypothetical protein 0.0023 0.0006 0.0006
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.0022 0.0006 0.0007
Plasmodium vivax topoisomerase I, putative 1.2154 1 1
Brugia malayi intermediate filament protein 0.0056 0.0033 0.0033
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0021 0.0004 0.0004
Echinococcus multilocularis Niemann Pick C1 protein 0.0096 0.0066 0.0066
Echinococcus granulosus g protein coupled receptor 0.0021 0.0004 0.0004
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0069 0.0044 0.0058
Brugia malayi nuclear receptor NHR-88 0.0181 0.0136 0.0136
Trichomonas vaginalis set domain proteins, putative 0.05 0.0399 0.8392
Trypanosoma brucei short-chain dehydrogenase, putative 0.0023 0.0006 0.0008
Echinococcus multilocularis Multi antimicrobial extrusion protein MatE 0.0063 0.0039 0.0039
Brugia malayi Transient-receptor-potential like protein 0.0072 0.0047 0.0047
Brugia malayi hypothetical protein 0.0021 0.0004 0.0004
Trichomonas vaginalis PIKK family atypical protein kinase 0.0036 0.0017 0.0346

Activities

Activity type Activity value Assay description Source Reference
Potency (functional) 0.0239 uM PUBCHEM_BIOASSAY: qHTS profiling assay for firefly luciferase inhibitor/activator using purified enzyme and Km concentrations of substrates (counterscreen for miR-21 project). (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID2288, AID2289, AID2598, AID411] ChEMBL. No reference
Potency (functional) = 0.7943 um PUBCHEM_BIOASSAY: qHTS Assay for Modulators of Lamin A Splicing. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) 1.2995 uM PubChem BioAssay. A quantitative high throughput screen for small molecules that induce DNA re-replication in SW480 colon adenocarcinoma cells. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) 8.2753 uM PUBCHEM_BIOASSAY: Primary qHTS for delayed death inhibitors of the malarial parasite plastid, 96 hour incubation. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID488745, AID488752, AID488774, AID504848, AID504850] ChEMBL. No reference
Potency (functional) 10 uM PubChem BioAssay. qHTS Assay for Inhibitors of the Human Apurinic/apyrimidinic Endonuclease 1 (APE1). (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) 18.526 uM PUBCHEM_BIOASSAY: Primary qHTS for delayed death inhibitors of the malarial parasite plastid, 48 hour incubation. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID488752, AID488774, AID504848, AID504850] ChEMBL. No reference
Potency (functional) 35.4813 uM PubChem BioAssay. qHTS for Antagonists of gsp, the Etiologic Mutation Responsible for Fibrous Dysplasia/McCune-Albright Syndrome: qHTS. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) 39.8107 uM PUBCHEM_BIOASSAY: qHTS Assay for Inhibitors of JMJD2A-Tudor Domain. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID504402] ChEMBL. No reference
Potency (functional) 79.4328 uM PUBCHEM_BIOASSAY: HTS for Inhibitors of HP1-beta Chromodomain Interactions with Methylated Histone Tails. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID488962] ChEMBL. No reference

Phenotypes

Whole-cell/tissue/organism interactions

Species name Source Reference Is orphan
Plasmodium falciparum ChEMBL23

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

No literature references available for this target.

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