Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Leishmania major | heat shock protein 83-1 | 0.0099 | 0.7408 | 0.5869 |
Schistosoma mansoni | short chain dehydrogenase | 0.0113 | 1 | 1 |
Echinococcus granulosus | steroid dehydrogenase | 0.0113 | 1 | 1 |
Echinococcus granulosus | heat shock protein 90 | 0.0099 | 0.7408 | 0.5869 |
Trichomonas vaginalis | short-chain dehydrogenase, putative | 0.0113 | 1 | 1 |
Mycobacterium tuberculosis | Decaprenylphosphoryl-D-2-keto erythro pentose reductase | 0.0113 | 1 | 1 |
Leishmania major | heat shock protein 83-1 | 0.0099 | 0.7408 | 0.5869 |
Mycobacterium ulcerans | dehydrogenase | 0.0113 | 1 | 1 |
Echinococcus multilocularis | carbonyl reductase 1 | 0.0113 | 1 | 1 |
Trypanosoma cruzi | Heat shock protein 83, putative | 0.0099 | 0.7408 | 0.7408 |
Echinococcus multilocularis | 3 ketodihydrosphingosine reductase | 0.0113 | 1 | 1 |
Trypanosoma cruzi | heat shock protein 90, putative | 0.0099 | 0.7408 | 0.7408 |
Mycobacterium ulcerans | short chain dehydrogenase | 0.0113 | 1 | 1 |
Mycobacterium ulcerans | short chain dehydrogenase | 0.0113 | 1 | 1 |
Trichomonas vaginalis | heat shock protein, putative | 0.0099 | 0.7408 | 0.7295 |
Entamoeba histolytica | hypothetical protein, conserved | 0.0113 | 1 | 1 |
Mycobacterium ulcerans | short chain dehydrogenase | 0.0113 | 1 | 1 |
Schistosoma mansoni | steroid dehydrogenase | 0.0113 | 1 | 1 |
Mycobacterium leprae | PROBABLE SHORT CHAIN ALCOHOL DEHYDROGENASE/REDUCTASE | 0.0113 | 1 | 1 |
Schistosoma mansoni | carbonyl reductase | 0.0113 | 1 | 1 |
Mycobacterium ulcerans | dehydrogenase/decarboxylase protein | 0.0113 | 1 | 1 |
Echinococcus granulosus | carbonyl reductase 1 | 0.0113 | 1 | 1 |
Echinococcus granulosus | carbonyl reductase 1 | 0.0113 | 1 | 1 |
Entamoeba histolytica | hypothetical protein | 0.0113 | 1 | 1 |
Entamoeba histolytica | estradiol 17-beta-dehydrogenase, putative | 0.0113 | 1 | 1 |
Onchocerca volvulus | 0.0113 | 1 | 0.5 | |
Loa Loa (eye worm) | hypothetical protein | 0.0113 | 1 | 1 |
Onchocerca volvulus | 0.0113 | 1 | 0.5 | |
Mycobacterium tuberculosis | Probable short-chain type dehydrogenase/reductase | 0.0113 | 1 | 1 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0113 | 1 | 1 |
Loa Loa (eye worm) | oxidoreductase | 0.0113 | 1 | 1 |
Schistosoma mansoni | steroid dehydrogenase | 0.0113 | 1 | 1 |
Mycobacterium leprae | Probable short-chain type dehydrogenase/reductase | 0.0113 | 1 | 1 |
Trypanosoma cruzi | NAD(P)-dependent oxidoreductase, putative | 0.0113 | 1 | 1 |
Leishmania major | quinonoid dihydropteridine reductase | 0.0113 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0113 | 1 | 1 |
Mycobacterium ulcerans | short chain dehydrogenase | 0.0113 | 1 | 1 |
Trypanosoma brucei | short-chain dehydrogenase, putative | 0.0113 | 1 | 1 |
Loa Loa (eye worm) | oxidoreductase | 0.0113 | 1 | 1 |
Mycobacterium ulcerans | 3-alpha-hydroxysteroid dehydrogenase | 0.0113 | 1 | 1 |
Echinococcus multilocularis | 3 hydroxyacyl coenzyme A dehydrogenase type 2 | 0.0113 | 1 | 1 |
Brugia malayi | oxidoreductase, short chain dehydrogenase/reductase family protein | 0.0113 | 1 | 1 |
Leishmania major | heat shock protein 83-1 | 0.0099 | 0.7408 | 0.5869 |
Trichomonas vaginalis | short-chain dehydrogenase, putative | 0.0113 | 1 | 1 |
Onchocerca volvulus | 0.0113 | 1 | 0.5 | |
Schistosoma mansoni | steroid dehydrogenase | 0.0113 | 1 | 1 |
Brugia malayi | oxidoreductase, short chain dehydrogenase/reductase family protein | 0.0113 | 1 | 1 |
Echinococcus multilocularis | estradiol 17 beta dehydrogenase 12 | 0.0113 | 1 | 1 |
Trypanosoma cruzi | short-chain dehydrogenase, putative | 0.0113 | 1 | 1 |
Plasmodium falciparum | steroid dehydrogenase, putative | 0.0113 | 1 | 1 |
Mycobacterium ulcerans | short-chain type dehydrogenase/reductase | 0.0113 | 1 | 1 |
Mycobacterium tuberculosis | Probable short-chain type dehydrogenase/reductase | 0.0113 | 1 | 1 |
Mycobacterium tuberculosis | Probable short-chain type dehydrogenase/reductase | 0.0113 | 1 | 1 |
Mycobacterium ulcerans | short-chain type dehydrogenase/reductase | 0.0113 | 1 | 1 |
Schistosoma mansoni | short chain dehydrogenase | 0.0113 | 1 | 1 |
Toxoplasma gondii | sterol carrier protein-2 HAD-2SCP-2 | 0.0113 | 1 | 1 |
Leishmania major | hypothetical protein, conserved | 0.0113 | 1 | 1 |
Trichomonas vaginalis | estradiol 17 beta-dehydrogenase, putative | 0.0113 | 1 | 1 |
Mycobacterium ulcerans | short-chain type dehydrogenase/reductase | 0.0113 | 1 | 1 |
Onchocerca volvulus | 0.0113 | 1 | 0.5 | |
Mycobacterium tuberculosis | Possible ketoacyl reductase | 0.0113 | 1 | 1 |
Trichomonas vaginalis | steroid dehydrogenase, putative | 0.0113 | 1 | 1 |
Trypanosoma cruzi | heat shock protein 85, putative | 0.0099 | 0.7408 | 0.7408 |
Entamoeba histolytica | estradiol 17-beta-dehydrogenase, putative | 0.0113 | 1 | 1 |
Mycobacterium ulcerans | short chain dehydrogenase | 0.0113 | 1 | 1 |
Mycobacterium ulcerans | short chain dehydrogenase | 0.0113 | 1 | 1 |
Brugia malayi | Retinol dehydrogenase 12 | 0.0113 | 1 | 1 |
Mycobacterium ulcerans | short chain dehydrogenase | 0.0113 | 1 | 1 |
Mycobacterium ulcerans | oxidoreductase | 0.0113 | 1 | 1 |
Mycobacterium ulcerans | short chain dehydrogenase | 0.0113 | 1 | 1 |
Loa Loa (eye worm) | oxidoreductase | 0.0113 | 1 | 1 |
Mycobacterium ulcerans | short-chain type dehydrogenase/reductase | 0.0113 | 1 | 1 |
Schistosoma mansoni | 3-hydroxyacyl-CoA dehydrogenase | 0.0113 | 1 | 1 |
Wolbachia endosymbiont of Brugia malayi | Short-chain alcohol dehydrogenase family enzyme | 0.0113 | 1 | 1 |
Leishmania major | oxidoreductase-like protein | 0.0113 | 1 | 1 |
Mycobacterium ulcerans | short-chain type dehydrogenase/reductase | 0.0113 | 1 | 1 |
Leishmania major | heat shock protein 83-1 | 0.0099 | 0.7408 | 0.5869 |
Schistosoma mansoni | short chain dehydrogenase | 0.0113 | 1 | 1 |
Mycobacterium tuberculosis | Probable dehydrogenase/reductase | 0.0113 | 1 | 1 |
Trypanosoma brucei | short-chain dehydrogenase, putative | 0.0113 | 1 | 1 |
Trypanosoma cruzi | 3-ketoacyl-CoA reductase, putative | 0.0113 | 1 | 1 |
Echinococcus multilocularis | oxidoreductase | 0.0113 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0113 | 1 | 1 |
Mycobacterium ulcerans | short chain dehydrogenase | 0.0113 | 1 | 1 |
Echinococcus multilocularis | heat shock protein | 0.0099 | 0.7408 | 0.5869 |
Schistosoma mansoni | short chain dehydrogenase | 0.0113 | 1 | 1 |
Trypanosoma cruzi | quinonoid dihydropteridine reductase, putative | 0.0113 | 1 | 1 |
Mycobacterium ulcerans | short chain dehydrogenase | 0.0113 | 1 | 1 |
Brugia malayi | Hypothetical oxidoreductase F56D1.5 | 0.0113 | 1 | 1 |
Mycobacterium ulcerans | short-chain membrane-associated dehydrogenase | 0.0113 | 1 | 1 |
Echinococcus multilocularis | conserved hypothetical protein | 0.0113 | 1 | 1 |
Plasmodium falciparum | heat shock protein 90 | 0.0099 | 0.7408 | 0.7295 |
Trypanosoma cruzi | 3-keto-dihydrosphingosine reductase | 0.0113 | 1 | 1 |
Mycobacterium leprae | ROBABLE SHORT-CHAIN TYPE DEHYDROGENASE/REDUCTASE | 0.0113 | 1 | 1 |
Trypanosoma brucei | short-chain dehydrogenase, putative | 0.0113 | 1 | 1 |
Plasmodium vivax | steroid dehydrogenase, putative | 0.0113 | 1 | 1 |
Leishmania major | heat shock protein 83-1 | 0.0099 | 0.7408 | 0.5869 |
Trypanosoma cruzi | short chain dehydrogenase/reductase, putative | 0.0113 | 1 | 1 |
Echinococcus multilocularis | retinol dehydrogenase 11 | 0.0113 | 1 | 1 |
Onchocerca volvulus | 0.0113 | 1 | 0.5 | |
Trichomonas vaginalis | hydroxyacyl dehydrogenase, putative | 0.0113 | 1 | 1 |
Leishmania major | heat shock protein 83-1 | 0.0099 | 0.7408 | 0.5869 |
Trichomonas vaginalis | heat shock protein, putative | 0.0079 | 0.3726 | 0.3452 |
Leishmania major | heat shock protein 83-1 | 0.0099 | 0.7408 | 0.5869 |
Giardia lamblia | Short-chain dehydrogenase, putative | 0.0113 | 1 | 1 |
Mycobacterium ulcerans | short chain dehydrogenase | 0.0113 | 1 | 1 |
Onchocerca volvulus | Dehydrogenase\/reductase SDR family member 13 homolog | 0.0113 | 1 | 0.5 |
Mycobacterium tuberculosis | Probable short chain alcohol dehydrogenase/reductase | 0.0113 | 1 | 1 |
Mycobacterium tuberculosis | Probable short-chain type oxidoreductase | 0.0113 | 1 | 1 |
Leishmania major | quinonoid dihydropteridine reductase | 0.0113 | 1 | 1 |
Leishmania major | short chain dehydrogenase-like protein | 0.0113 | 1 | 1 |
Mycobacterium tuberculosis | Possible short-chain dehydrogenase EphD | 0.0113 | 1 | 1 |
Trypanosoma cruzi | short chain dehydrogenase, putative | 0.0113 | 1 | 1 |
Leishmania major | heat shock protein 83-1 | 0.0099 | 0.7408 | 0.5869 |
Echinococcus granulosus | epidermal retinal dehydrogenase 2 | 0.0113 | 1 | 1 |
Brugia malayi | oxidoreductase, short chain dehydrogenase/reductase family protein | 0.0113 | 1 | 1 |
Leishmania major | hypothetical protein, conserved | 0.0113 | 1 | 1 |
Mycobacterium ulcerans | oxidoreductase | 0.0113 | 1 | 1 |
Trichomonas vaginalis | short-chain dehydrogenase, putative | 0.0113 | 1 | 1 |
Mycobacterium tuberculosis | Probable dehydrogenase/reductase | 0.0113 | 1 | 1 |
Schistosoma mansoni | short chain dehydrogenase | 0.0113 | 1 | 1 |
Trypanosoma cruzi | short chain dehydrogenase/reductase, putative | 0.0113 | 1 | 1 |
Mycobacterium ulcerans | short-chain type dehydrogenase/reductase | 0.0113 | 1 | 1 |
Mycobacterium ulcerans | short chain dehydrogenase | 0.0113 | 1 | 1 |
Leishmania major | short chain dehydrogenase, putative | 0.0113 | 1 | 1 |
Mycobacterium tuberculosis | Possible iron-regulated short-chain dehydrogenase/reductase | 0.0113 | 1 | 1 |
Mycobacterium ulcerans | short chain dehydrogenase | 0.0113 | 1 | 1 |
Schistosoma mansoni | steroid dehydrogenase | 0.0113 | 1 | 1 |
Leishmania major | hypothetical protein, conserved | 0.0113 | 1 | 1 |
Brugia malayi | oxidoreductase, short chain dehydrogenase/reductase family protein | 0.0113 | 1 | 1 |
Loa Loa (eye worm) | oxidoreductase | 0.0113 | 1 | 1 |
Mycobacterium tuberculosis | Possible multi-functional enzyme with acyl-CoA-reductase activity AcrA1 | 0.0113 | 1 | 1 |
Echinococcus granulosus | 3 hydroxyacyl coenzyme A dehydrogenase type 2 | 0.0113 | 1 | 1 |
Echinococcus multilocularis | Dehydrogenase:reductase SDR family | 0.0113 | 1 | 1 |
Leishmania major | heat shock protein 83-1 | 0.0099 | 0.7408 | 0.5869 |
Entamoeba histolytica | short chain dehydrogenase family protein | 0.0113 | 1 | 1 |
Brugia malayi | Dehydrogenases, short chain protein 2 | 0.0113 | 1 | 1 |
Leishmania major | hypothetical protein, conserved | 0.0113 | 1 | 1 |
Schistosoma mansoni | steroid dehydrogenase | 0.0113 | 1 | 1 |
Brugia malayi | dehydrogenases, short chain protein 2 | 0.0113 | 1 | 1 |
Trypanosoma brucei | short-chain dehydrogenase, putative | 0.0113 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0113 | 1 | 1 |
Giardia lamblia | Oxidoreductase, short chain dehydrogenase/reductase family | 0.0113 | 1 | 1 |
Loa Loa (eye worm) | dehydrogenase | 0.0113 | 1 | 1 |
Trichomonas vaginalis | short-chain dehydrogenase, putative | 0.0113 | 1 | 1 |
Toxoplasma gondii | oxidoreductase, short chain dehydrogenase/reductase family protein | 0.0113 | 1 | 1 |
Schistosoma mansoni | short chain dehydrogenase | 0.0113 | 1 | 1 |
Loa Loa (eye worm) | oxidoreductase | 0.0113 | 1 | 1 |
Trypanosoma cruzi | oxidoreductase-like protein, putative | 0.0113 | 1 | 1 |
Mycobacterium tuberculosis | Probable dehydrogenase | 0.0113 | 1 | 1 |
Onchocerca volvulus | 0.0113 | 1 | 0.5 | |
Trypanosoma cruzi | oxidoreductase-like protein, putative | 0.0113 | 1 | 1 |
Trichomonas vaginalis | short-chain dehydrogenase, putative | 0.0113 | 1 | 1 |
Trypanosoma cruzi | heat shock protein 85, putative | 0.0099 | 0.7408 | 0.7408 |
Toxoplasma gondii | oxidoreductase, short chain dehydrogenase/reductase family protein | 0.0113 | 1 | 1 |
Echinococcus multilocularis | steroid dehydrogenase | 0.0113 | 1 | 1 |
Leishmania major | quinonoid dihydropteridine reductase | 0.0113 | 1 | 1 |
Schistosoma mansoni | short chain dehydrogenase | 0.0113 | 1 | 1 |
Brugia malayi | D-beta-hydroxybutyrate dehydrogenase, mitochondrial precursor | 0.0113 | 1 | 1 |
Mycobacterium ulcerans | short chain dehydrogenase | 0.0113 | 1 | 1 |
Echinococcus granulosus | oxidoreductase | 0.0113 | 1 | 1 |
Brugia malayi | hypothetical protein | 0.0113 | 1 | 1 |
Trypanosoma brucei | beta-ketoacyl-ACP reductase 3, putative | 0.0113 | 1 | 1 |
Schistosoma mansoni | steroid dehydrogenase | 0.0113 | 1 | 1 |
Giardia lamblia | Hypothetical protein | 0.0113 | 1 | 1 |
Echinococcus granulosus | carbonyl reductase 1 | 0.0113 | 1 | 1 |
Trypanosoma cruzi | 3-keto-dihydrosphingosine reductase | 0.0113 | 1 | 1 |
Treponema pallidum | heat shock protein 90 | 0.0079 | 0.3726 | 0.5 |
Trypanosoma brucei | 3-ketoacyl-CoA reductase, putative | 0.0113 | 1 | 1 |
Mycobacterium ulcerans | short chain dehydrogenase | 0.0113 | 1 | 1 |
Echinococcus multilocularis | heat shock protein 90 | 0.0099 | 0.7408 | 0.5869 |
Brugia malayi | oxidoreductase, short chain dehydrogenase/reductase family protein | 0.0113 | 1 | 1 |
Trypanosoma cruzi | beta-ketoacyl-ACP reductase 2, putative | 0.0113 | 1 | 1 |
Schistosoma mansoni | retinal dehydrogenase | 0.0113 | 1 | 1 |
Brugia malayi | oxidoreductase, short chain dehydrogenase/reductase family protein | 0.0113 | 1 | 1 |
Mycobacterium tuberculosis | Probable oxidoreductase | 0.0113 | 1 | 1 |
Brugia malayi | Dehydrogenases, short chain protein 30 | 0.0113 | 1 | 1 |
Mycobacterium ulcerans | short chain dehydrogenase | 0.0113 | 1 | 1 |
Mycobacterium ulcerans | short-chain dehydrogenase | 0.0113 | 1 | 1 |
Giardia lamblia | Heat shock protein HSP 90-alpha | 0.0099 | 0.7408 | 0.5869 |
Entamoeba histolytica | 3-ketodihydrosphingosine reductase protein, putative | 0.0113 | 1 | 1 |
Brugia malayi | oxidoreductase, short chain dehydrogenase/reductase family protein | 0.0113 | 1 | 1 |
Brugia malayi | oxidoreductase, short chain dehydrogenase/reductase family protein | 0.0113 | 1 | 1 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0113 | 1 | 1 |
Loa Loa (eye worm) | oxidoreductase | 0.0113 | 1 | 1 |
Mycobacterium ulcerans | short-chain type oxidoreductase | 0.0113 | 1 | 1 |
Trypanosoma cruzi | 3-ketoacyl-CoA reductase, putative | 0.0113 | 1 | 1 |
Trichomonas vaginalis | short-chain dehydrogenase, putative | 0.0113 | 1 | 1 |
Toxoplasma gondii | 2,4-dienoyl CoA reductase 2, peroxisomal family protein | 0.0113 | 1 | 1 |
Mycobacterium tuberculosis | Probable oxidoreductase | 0.0113 | 1 | 1 |
Mycobacterium tuberculosis | Probable short-chain type dehydrogenase/reductase | 0.0113 | 1 | 1 |
Schistosoma mansoni | short-chain dehydrogenase/reductase | 0.0113 | 1 | 1 |
Schistosoma mansoni | short chain dehydrogenase | 0.0113 | 1 | 1 |
Loa Loa (eye worm) | dehydrogenase | 0.0113 | 1 | 1 |
Mycobacterium ulcerans | short-chain type dehydrogenase/reductase | 0.0113 | 1 | 1 |
Echinococcus granulosus | carbonyl reductase 1 | 0.0113 | 1 | 1 |
Mycobacterium tuberculosis | Possible fatty acyl-CoA reductase | 0.0113 | 1 | 1 |
Trypanosoma cruzi | NAD(P)-dependent oxidoreductase, putative | 0.0113 | 1 | 1 |
Trichomonas vaginalis | heat shock protein, putative | 0.0079 | 0.3726 | 0.3452 |
Onchocerca volvulus | 0.0113 | 1 | 0.5 | |
Plasmodium falciparum | conserved Plasmodium protein, unknown function | 0.0113 | 1 | 1 |
Leishmania major | heat shock protein 83-1 | 0.0099 | 0.7408 | 0.5869 |
Leishmania major | short chain dehydrogenase, putative | 0.0113 | 1 | 1 |
Schistosoma mansoni | short chain dehydrogenase | 0.0113 | 1 | 1 |
Mycobacterium tuberculosis | Probable oxidoreductase | 0.0113 | 1 | 1 |
Schistosoma mansoni | oxidoreductase short chain dehydrogenase/reductase family | 0.0113 | 1 | 1 |
Trypanosoma brucei | 3-keto-dihydrosphingosine reductase | 0.0113 | 1 | 1 |
Trichomonas vaginalis | short-chain dehydrogenases/reductase, putative | 0.0113 | 1 | 1 |
Mycobacterium ulcerans | short chain dehydrogenase | 0.0113 | 1 | 1 |
Schistosoma mansoni | carbonyl reductase | 0.0113 | 1 | 1 |
Schistosoma mansoni | short chain dehydrogenase | 0.0113 | 1 | 1 |
Schistosoma mansoni | short chain dehydrogenase | 0.0113 | 1 | 1 |
Trypanosoma cruzi | heat shock protein 85, putative | 0.0079 | 0.3726 | 0.3726 |
Trichomonas vaginalis | short-chain dehydrogenase, putative | 0.0113 | 1 | 1 |
Leishmania major | heat shock protein 83-1 | 0.0099 | 0.7408 | 0.5869 |
Mycobacterium ulcerans | short chain dehydrogenase | 0.0113 | 1 | 1 |
Brugia malayi | 3-hydroxyacyl-CoA dehydrogenase type II | 0.0113 | 1 | 1 |
Brugia malayi | oxidoreductase | 0.0113 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0113 | 1 | 1 |
Mycobacterium ulcerans | ketoacyl reductase | 0.0113 | 1 | 1 |
Mycobacterium ulcerans | ketoacyl reductase | 0.0113 | 1 | 1 |
Leishmania major | heat shock protein 83-1 | 0.0099 | 0.7408 | 0.5869 |
Onchocerca volvulus | 0.0113 | 1 | 0.5 | |
Schistosoma mansoni | short chain dehydrogenase | 0.0113 | 1 | 1 |
Brugia malayi | oxidoreductase, short chain dehydrogenase/reductase family protein | 0.0113 | 1 | 1 |
Echinococcus multilocularis | carbonyl reductase 1 | 0.0113 | 1 | 1 |
Mycobacterium leprae | Probable oxidoreductase | 0.0113 | 1 | 1 |
Trypanosoma cruzi | heat shock protein 85, putative | 0.0099 | 0.7408 | 0.7408 |
Brugia malayi | oxidoreductase, short chain dehydrogenase/reductase family protein | 0.0113 | 1 | 1 |
Brugia malayi | oxidoreductase, short chain dehydrogenase/reductase family protein | 0.0113 | 1 | 1 |
Brugia malayi | dehydrogenases, short chain protein 9 | 0.0113 | 1 | 1 |
Mycobacterium ulcerans | short chain dehydrogenase | 0.0113 | 1 | 1 |
Mycobacterium ulcerans | 3-ketoacyl-ACP reductase | 0.0113 | 1 | 1 |
Mycobacterium tuberculosis | Probable short-chain type dehydrogenase/reductase | 0.0113 | 1 | 1 |
Trypanosoma cruzi | short-chain dehydrogenase, putative | 0.0113 | 1 | 1 |
Brugia malayi | oxidoreductase, short chain dehydrogenase/reductase family protein | 0.0113 | 1 | 1 |
Mycobacterium ulcerans | short-chain type dehydrogenase/reductase | 0.0113 | 1 | 1 |
Onchocerca volvulus | Sepiapterin reductase homolog | 0.0113 | 1 | 0.5 |
Mycobacterium ulcerans | dehydrogenase/reductase | 0.0113 | 1 | 1 |
Leishmania major | pteridine reductase 1 | 0.0113 | 1 | 1 |
Leishmania major | short chain dehydrogenase/reductase, putative | 0.0113 | 1 | 1 |
Leishmania major | heat shock protein 83-1 | 0.0099 | 0.7408 | 0.5869 |
Mycobacterium tuberculosis | Probable oxidoreductase | 0.0113 | 1 | 1 |
Brugia malayi | oxidoreductase, short chain dehydrogenase/reductase family protein | 0.0113 | 1 | 1 |
Echinococcus multilocularis | steroid dehydrogenase | 0.0113 | 1 | 1 |
Schistosoma mansoni | short chain dehydrogenase | 0.0113 | 1 | 1 |
Schistosoma mansoni | steroid dehydrogenase | 0.0113 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0113 | 1 | 1 |
Brugia malayi | hypothetical protein | 0.0113 | 1 | 1 |
Leishmania major | quinonoid dihydropteridine reductase | 0.0113 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0113 | 1 | 1 |
Trichomonas vaginalis | heat shock protein, putative | 0.0079 | 0.3726 | 0.3452 |
Mycobacterium ulcerans | short-chain dehydrogenase | 0.0113 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0113 | 1 | 1 |
Trypanosoma brucei | short-chain dehydrogenase, putative | 0.0113 | 1 | 1 |
Leishmania major | short chain dehydrogenase/reductase, putative | 0.0113 | 1 | 1 |
Brugia malayi | oxidoreductase, short chain dehydrogenase/reductase family protein | 0.0113 | 1 | 1 |
Mycobacterium ulcerans | short-chain type dehydrogenase/reductase | 0.0113 | 1 | 1 |
Echinococcus granulosus | hypothetical protein | 0.0113 | 1 | 1 |
Leishmania major | dehydrogenase-like protein | 0.0113 | 1 | 1 |
Echinococcus multilocularis | retinol dehydrogenase 11 | 0.0113 | 1 | 1 |
Leishmania major | hypothetical protein, conserved | 0.0113 | 1 | 1 |
Onchocerca volvulus | Dehydrogenase\/reductase SDR family member 1 homolog | 0.0113 | 1 | 0.5 |
Plasmodium vivax | hypothetical protein, conserved | 0.0113 | 1 | 1 |
Echinococcus multilocularis | carbonyl reductase 1 | 0.0113 | 1 | 1 |
Schistosoma mansoni | steroid dehydrogenase | 0.0113 | 1 | 1 |
Schistosoma mansoni | 3-keto-dihydrosphingosine reductase | 0.0113 | 1 | 1 |
Echinococcus granulosus | heat shock protein | 0.0099 | 0.7408 | 0.5869 |
Mycobacterium ulcerans | short-chain type dehydrogenase/reductase | 0.0113 | 1 | 1 |
Mycobacterium tuberculosis | Possible oxidoreductase | 0.0113 | 1 | 1 |
Mycobacterium tuberculosis | Probable oxidoreductase | 0.0113 | 1 | 1 |
Leishmania major | heat shock protein 83-1 | 0.0099 | 0.7408 | 0.5869 |
Brugia malayi | oxidoreductase, short chain dehydrogenase/reductase family protein | 0.0113 | 1 | 1 |
Onchocerca volvulus | Dehydrogenase\/reductase SDR family member 13 homolog | 0.0113 | 1 | 0.5 |
Toxoplasma gondii | oxidoreductase, putative | 0.0113 | 1 | 1 |
Leishmania major | 3-oxoacyl-(acyl-carrier protein) reductase, putative | 0.0113 | 1 | 1 |
Mycobacterium tuberculosis | Probable short-chain type dehydrogenase/reductase | 0.0113 | 1 | 1 |
Mycobacterium ulcerans | carveol-like dehydrogenase | 0.0113 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0113 | 1 | 1 |
Schistosoma mansoni | short chain dehydrogenase | 0.0113 | 1 | 1 |
Trypanosoma cruzi | heat shock protein 90, putative | 0.0079 | 0.3726 | 0.3726 |
Loa Loa (eye worm) | short chain dehydrogenase/reductase family oxidoreductase | 0.0113 | 1 | 1 |
Mycobacterium ulcerans | short chain dehydrogenase | 0.0113 | 1 | 1 |
Echinococcus multilocularis | carbonyl reductase 1 | 0.0113 | 1 | 1 |
Trypanosoma brucei | beta-D-hydroxybutyrate dehydrogenase | 0.0113 | 1 | 1 |
Schistosoma mansoni | carbonyl reductase | 0.0113 | 1 | 1 |
Mycobacterium leprae | Probable short-chain type dehydrogenase/reductase | 0.0113 | 1 | 1 |
Echinococcus multilocularis | epidermal retinal dehydrogenase 2 | 0.0113 | 1 | 1 |
Mycobacterium ulcerans | short-chain dehydrogenase | 0.0113 | 1 | 1 |
Onchocerca volvulus | 0.0113 | 1 | 0.5 | |
Trypanosoma brucei | beta-ketoacyl-ACP reductase 2 | 0.0113 | 1 | 1 |
Leishmania major | quinonoid dihydropteridine reductase | 0.0113 | 1 | 1 |
Leishmania major | 3-keto-dihydrosphingosine reductase | 0.0113 | 1 | 1 |
Schistosoma mansoni | steroid dehydrogenase | 0.0113 | 1 | 1 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0113 | 1 | 1 |
Mycobacterium ulcerans | short-chain dehydrogenase | 0.0113 | 1 | 1 |
Mycobacterium ulcerans | ketoacyl reductase | 0.0113 | 1 | 1 |
Toxoplasma gondii | carbonyl reductase 1, putative | 0.0113 | 1 | 1 |
Schistosoma mansoni | short chain dehydrogenase | 0.0113 | 1 | 1 |
Toxoplasma gondii | oxidoreductase, short chain dehydrogenase/reductase family protein | 0.0113 | 1 | 1 |
Loa Loa (eye worm) | oxidoreductase | 0.0113 | 1 | 1 |
Loa Loa (eye worm) | oxidoreductase | 0.0113 | 1 | 1 |
Echinococcus granulosus | hypothetical protein | 0.0113 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0113 | 1 | 1 |
Entamoeba histolytica | oxidoreductase, short chain dehydrogenase/reductase family | 0.0113 | 1 | 1 |
Mycobacterium tuberculosis | Probable short-chain dehydrogenase/reductase | 0.0113 | 1 | 1 |
Trypanosoma cruzi | short chain dehydrogenase, putative | 0.0113 | 1 | 1 |
Onchocerca volvulus | 0.0113 | 1 | 0.5 | |
Leishmania major | heat shock protein 83-1 | 0.0099 | 0.7408 | 0.5869 |
Echinococcus multilocularis | transient receptor potential cation channel | 0.0113 | 1 | 1 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0113 | 1 | 1 |
Entamoeba histolytica | short chain dehydrogenase family protein | 0.0113 | 1 | 1 |
Toxoplasma gondii | oxidoreductase, short chain dehydrogenase/reductase family protein | 0.0113 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0113 | 1 | 1 |
Echinococcus granulosus | 3 ketodihydrosphingosine reductase | 0.0113 | 1 | 1 |
Brugia malayi | oxidoreductase, short chain dehydrogenase/reductase family protein | 0.0113 | 1 | 1 |
Schistosoma mansoni | steroid dehydrogenase | 0.0113 | 1 | 1 |
Mycobacterium ulcerans | short chain dehydrogenase | 0.0113 | 1 | 1 |
Trichomonas vaginalis | short-chain dehydrogenase, putative | 0.0113 | 1 | 1 |
Toxoplasma gondii | oxidoreductase, short chain dehydrogenase/reductase family protein | 0.0113 | 1 | 1 |
Leishmania major | heat shock protein 83-1 | 0.0099 | 0.7408 | 0.5869 |
Echinococcus granulosus | retinol dehydrogenase 11 | 0.0113 | 1 | 1 |
Brugia malayi | oxidoreductase, short chain dehydrogenase/reductase family protein | 0.0113 | 1 | 1 |
Entamoeba histolytica | estradiol 17-beta-dehydrogenase, putative | 0.0113 | 1 | 1 |
Mycobacterium tuberculosis | Possible oxidoreductase | 0.0113 | 1 | 1 |
Toxoplasma gondii | oxidoreductase, putative | 0.0113 | 1 | 1 |
Onchocerca volvulus | 0.0113 | 1 | 0.5 | |
Echinococcus granulosus | Dehydrogenase:reductase SDR family | 0.0113 | 1 | 1 |
Onchocerca volvulus | 0.0113 | 1 | 0.5 | |
Leishmania major | quinonoid dihydropteridine reductase | 0.0113 | 1 | 1 |
Echinococcus granulosus | WW domain containing oxidoreductase | 0.0113 | 1 | 1 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0113 | 1 | 1 |
Trypanosoma brucei | oxidoreductase-like protein | 0.0113 | 1 | 1 |
Plasmodium falciparum | oxidoreductase, short-chain dehydrogenase family, putative | 0.0113 | 1 | 1 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0113 | 1 | 1 |
Mycobacterium tuberculosis | Probable shortchain dehydrogenase | 0.0113 | 1 | 1 |
Loa Loa (eye worm) | oxidoreductase | 0.0113 | 1 | 1 |
Entamoeba histolytica | hypothetical protein, conserved | 0.0113 | 1 | 1 |
Mycobacterium tuberculosis | Probable short-chain type dehydrogenase/reductase | 0.0113 | 1 | 1 |
Leishmania major | heat shock protein 83-1 | 0.0099 | 0.7408 | 0.5869 |
Giardia lamblia | Reductase, putative | 0.0113 | 1 | 1 |
Echinococcus multilocularis | retinol dehydrogenase 13 | 0.0113 | 1 | 1 |
Onchocerca volvulus | 0.0113 | 1 | 0.5 | |
Echinococcus granulosus | retinol dehydrogenase 11 | 0.0113 | 1 | 1 |
Leishmania major | quinonoid dihydropteridine reductase | 0.0113 | 1 | 1 |
Mycobacterium ulcerans | short-chain type dehydrogenase/reductase | 0.0113 | 1 | 1 |
Mycobacterium leprae | Possible short-chain dehydrogenase EphD | 0.0113 | 1 | 1 |
Trypanosoma cruzi | beta-ketoacyl-ACP reductase 2, putative | 0.0113 | 1 | 1 |
Mycobacterium tuberculosis | Probable oxidoreductase | 0.0113 | 1 | 1 |
Mycobacterium ulcerans | short chain dehydrogenase | 0.0113 | 1 | 1 |
Toxoplasma gondii | 3-ketoacyl-CoA reductase, putative | 0.0113 | 1 | 1 |
Activity type | Activity value | Assay description | Source | Reference |
---|---|---|---|---|
Inhibition (binding) | < 10 % | Inhibition of GST-tagged human SIRT1 (133 to 747 amino acids) using ZMAL as substrate at 200 uM after 4 hrs by fluorescence-based microplate reader method | ChEMBL. | 26696402 |
Inhibition (binding) | < 10 % | Inhibition of N-terminal his6-tagged human SIRT2 (25 to 389 amino acids) using ZMAL as substrate at 50 uM after 4 hrs by fluorescence-based microplate reader method | ChEMBL. | 26696402 |
Potency (binding) | = 31.6228 um | PUBCHEM_BIOASSAY: qHTS Assay for Identification of Novel General Anesthetics. In this assay, a GABAergic mimetic model system, apoferritin and a profluorescent 1-aminoanthracene ligand (1-AMA), was used to construct a competitive binding assay for identification of novel general anesthetics (Class of assay: confirmatory) [Related pubchem assays: 2385 (Probe Development Summary for Identification of Novel General Anesthetics), 2323 (Validation apoferritin assay run on SigmaAldrich LOPAC1280 collection)] | ChEMBL. | No reference |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.
1 literature reference was collected for this gene.