Detailed information for compound 1395077

Basic information

Technical information
  • TDR Targets ID: 1395077
  • Name: 2-(cyclohexylcarbamoyl)cyclohexane-1-carboxyl ic acid
  • MW: 253.337 | Formula: C14H23NO3
  • H donors: 2 H acceptors: 3 LogP: 2.42 Rotable bonds: 4
    Rule of 5 violations (Lipinski): 1
  • SMILES: OC(=O)C1CCCCC1C(=O)NC1CCCCC1
  • InChi: 1S/C14H23NO3/c16-13(15-10-6-2-1-3-7-10)11-8-4-5-9-12(11)14(17)18/h10-12H,1-9H2,(H,15,16)(H,17,18)
  • InChiKey: WFIVKODHWKTHAC-UHFFFAOYSA-N  

Network

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Synonyms

  • 2-[(cyclohexylamino)-oxomethyl]-1-cyclohexanecarboxylic acid
  • Oprea1_353503
  • 2-[(cyclohexylamino)carbonyl]cyclohexanecarboxylic acid
  • MLS000061078
  • SMR000069591
  • 2-Cyclohexylcarbamoyl-cyclohexanecarboxylic acid
  • BAS 00329147
  • Oprea1_713834

Targets

Known targets for this compound

Species Target name Source Bibliographic reference
Homo sapiens GNAS complex locus Starlite/ChEMBL No references

Predicted pathogen targets for this compound

By orthology
Species Potential target Known druggable target/s Ortholog Group
Echinococcus granulosus guanine nucleotide binding protein Gs subunit Get druggable targets OG5_131088 All targets in OG5_131088
Echinococcus granulosus guanine nucleotide binding protein Gs subunit Get druggable targets OG5_131088 All targets in OG5_131088
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit Get druggable targets OG5_131088 All targets in OG5_131088
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain Get druggable targets OG5_131088 All targets in OG5_131088
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) Get druggable targets OG5_131088 All targets in OG5_131088
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit Get druggable targets OG5_131088 All targets in OG5_131088
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) Get druggable targets OG5_131088 All targets in OG5_131088
Schistosoma japonicum ko:K04632 guanine nucleotide binding protein (G protein), alpha stimulating, putative Get druggable targets OG5_131088 All targets in OG5_131088
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) Get druggable targets OG5_131088 All targets in OG5_131088
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative Get druggable targets OG5_131088 All targets in OG5_131088

By sequence similarity to non orthologous known druggable targets
Species Potential target Known druggable target Length Alignment span Identity
Schistosoma mansoni GTP-binding protein alpha subunit gna GNAS complex locus 394 aa 450 aa 28.7 %

Obtained from network model

Ranking Plot


Putative Targets List


Species Potential target Raw Global Species
Schistosoma mansoni tubulin subunit alpha 0.0902 0.2816 0.4301
Echinococcus multilocularis ATP dependent DNA helicase Q5 0.0028 0.0029 0.0029
Trypanosoma brucei acyl transferase-like protein 0.0063 0.014 0.0372
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.023 0.0675 0.128
Trichomonas vaginalis phosphofructokinase, putative 0.0029 0.0032 0.0074
Wolbachia endosymbiont of Brugia malayi cell division protein FtsZ 0.0278 0.0826 1
Echinococcus granulosus GA binding protein alpha chain 0.0068 0.0157 0.024
Trichomonas vaginalis phosphofructokinase, putative 0.0029 0.0032 0.0074
Brugia malayi Cytochrome P450 family protein 0.0038 0.0061 0.0103
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0095 0.0243 0.0371
Mycobacterium ulcerans DNA polymerase IV 0.0059 0.0128 0.0234
Trypanosoma brucei Poly(ADP-ribose) polymerase and DNA-Ligase Zn-finger region/Zinc-finger (CX5CX6HX5H) motif containing protein, putative 0.0058 0.0126 0.0332
Entamoeba histolytica phosphofructokinase, putative 0.0106 0.0279 0.0744
Mycobacterium ulcerans dehydrogenase 0.0062 0.0137 0.0253
Schistosoma mansoni hypothetical protein 0.0095 0.0243 0.0371
Loa Loa (eye worm) hypothetical protein 0.0041 0.007 0.0133
Brugia malayi hypothetical protein 0.0025 0.0018 0.003
Mycobacterium tuberculosis Probable polyketide synthase Pks9 0.0565 0.1743 0.3699
Schistosoma mansoni alpha tubulin 0.0902 0.2816 0.4301
Loa Loa (eye worm) hypothetical protein 0.005 0.0098 0.0186
Echinococcus granulosus histone lysine methyltransferase setb 0.0066 0.0151 0.023
Loa Loa (eye worm) hypothetical protein 0.0028 0.0029 0.0055
Echinococcus multilocularis Tubulin alpha 1 chain 0.0902 0.2816 0.2816
Schistosoma mansoni inositol monophosphatase 0.0041 0.0069 0.0106
Loa Loa (eye worm) hypothetical protein 0.0019 0.0001 0.0002
Echinococcus granulosus chromobox protein 1 0.0071 0.0166 0.0254
Schistosoma mansoni methyltransferase-related 0.03 0.0895 0.1367
Onchocerca volvulus 0.0937 0.2926 0.5173
Entamoeba histolytica acyl-CoA synthetase, putative 0.0025 0.0019 0.0032
Trypanosoma cruzi ATP-dependent 6-phosphofructokinase, glycosomal 0.0106 0.0279 0.0744
Loa Loa (eye worm) tubulin beta chain 0.0278 0.0826 0.1567
Mycobacterium tuberculosis Phenolpthiocerol synthesis type-I polyketide synthase PpsA 0.0995 0.3111 0.6635
Mycobacterium tuberculosis Phenolpthiocerol synthesis type-I polyketide synthase PpsE 0.0153 0.0426 0.0874
Schistosoma mansoni serine/threonine protein kinase 0.1068 0.3347 0.5111
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.0041 0.007 0.007
Trypanosoma brucei DNA polymerase kappa, putative 0.0036 0.0056 0.014
Echinococcus granulosus aldo keto reductase 0.0253 0.0747 0.114
Onchocerca volvulus 0.0046 0.0087 0.0154
Loa Loa (eye worm) hypothetical protein 0.0153 0.0426 0.0809
Mycobacterium leprae PROBABLE DNA LIGASE [NAD DEPENDENT] LIGA (POLYDEOXYRIBONUCLEOTIDE SYNTHASE [NAD+]) 0.0027 0.0025 0.0013
Echinococcus multilocularis RUN 0.0019 0.0002 0.0002
Mycobacterium tuberculosis Probable NADP-dependent alcohol dehydrogenase AdhC 0.0062 0.0137 0.0253
Plasmodium vivax hypothetical protein, conserved 0.015 0.0419 0.1142
Leishmania major importin beta-1 subunit, putative 0.0045 0.0084 0.0211
Trichomonas vaginalis conserved hypothetical protein 0.0091 0.023 0.0619
Trichomonas vaginalis DNA helicase recq1, putative 0.004 0.0068 0.0175
Echinococcus multilocularis phd:f box containing protein 0.004 0.0069 0.0069
Onchocerca volvulus 0.0022 0.001 0.0018
Brugia malayi Doublecortin family protein 0.0019 0.0002 0.0003
Schistosoma mansoni tubulin subunit epsilon 0.064 0.198 0.3024
Trichomonas vaginalis tubulin alpha-1 chain, putative 0.0624 0.193 0.5275
Trypanosoma brucei zeta tubulin 0.0278 0.0826 0.225
Loa Loa (eye worm) doublecortin family protein 0.0019 0.0002 0.0003
Mycobacterium leprae Probable oxidireductase 0.0062 0.0137 0.0253
Trichomonas vaginalis aldo-keto reductase, putative 0.0253 0.0747 0.2034
Echinococcus multilocularis Transcription factor, JmjC domain containing protein 0.0208 0.0603 0.0603
Trypanosoma brucei Trans-2-enoyl-ACP reductase 2, putative 0.0062 0.0137 0.0363
Echinococcus granulosus lamin 0.0027 0.0026 0.004
Loa Loa (eye worm) hypothetical protein 0.0091 0.0231 0.0439
Loa Loa (eye worm) hypothetical protein 0.0062 0.0137 0.026
Brugia malayi tailless protein 0.0019 0.0001 0.0002
Loa Loa (eye worm) CYP4Cod1 0.0038 0.0061 0.0117
Trichomonas vaginalis ATP-binding cassette transporter, putative 0.0023 0.0013 0.0024
Leishmania major DNA polymerase kappa, putative 0.0039 0.0066 0.016
Trypanosoma cruzi epsilon tubulin, putative 0.064 0.198 0.5409
Schistosoma mansoni smad1 5 8 and 0.0024 0.0017 0.0027
Trypanosoma brucei DNA polymerase kappa, putative 0.0039 0.0066 0.0168
Leishmania major ATP-binding cassette protein subfamily G, member 6, putative 0.0061 0.0135 0.035
Leishmania major alpha tubulin 0.0902 0.2816 0.77
Trichomonas vaginalis tubulin alpha-1 chain, putative 0.054 0.1662 0.454
Mycobacterium ulcerans phenolpthiocerol synthesis type-I polyketide synthase PpsA 0.08 0.2492 0.5305
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.0066 0.0152 0.0231
Entamoeba histolytica hypothetical protein 0.0091 0.023 0.0611
Mycobacterium leprae Possible oxidoreductase 0.0073 0.0174 0.0332
Echinococcus multilocularis ATP dependent DNA helicase Q1 0.0028 0.0029 0.0029
Schistosoma mansoni ubiquitously transcribed sex (X/Y) chromosome tetratricopeptide repeat protein-related 0.004 0.0069 0.0105
Loa Loa (eye worm) hypothetical protein 0.0027 0.0025 0.0048
Plasmodium vivax tubulin alpha chain, putative 0.0902 0.2816 0.7704
Onchocerca volvulus Protein ultraspiracle homolog 0.0041 0.007 0.0124
Schistosoma mansoni [ACP] S-malonyltransferase 0.0063 0.014 0.0214
Plasmodium vivax tubulin alpha chain, putative 0.0902 0.2816 0.7704
Trichomonas vaginalis DNA helicase recq, putative 0.0031 0.0037 0.009
Mycobacterium ulcerans zinc-containing alcohol dehydrogenase NAD-dependent AdhB 0.0062 0.0137 0.0253
Toxoplasma gondii beta-1 tubulin, putative 0.1165 0.3655 1
Loa Loa (eye worm) CMGC/MAPK/ERK1 protein kinase 0.1068 0.3347 0.6349
Toxoplasma gondii CMGC kinase, MAPK family (ERK) MAPK-1 0.1068 0.3347 0.9155
Echinococcus multilocularis tubulin alpha chain 0.0902 0.2816 0.2816
Loa Loa (eye worm) oxidoreductase 0.0253 0.0747 0.1417
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0041 0.0069 0.017
Schistosoma mansoni tubulin subunit beta 0.1165 0.3655 0.5582
Echinococcus granulosus aldehyde reductase 0.018 0.0513 0.0784
Schistosoma mansoni [ACP] S-malonyltransferase 0.0063 0.014 0.0214
Echinococcus granulosus acyl carrier protein mitochondrial 0.01 0.026 0.0398
Entamoeba histolytica ABC transporter, putative 0.0061 0.0135 0.035
Loa Loa (eye worm) hypothetical protein 0.0022 0.001 0.002
Schistosoma mansoni bromodomain containing protein 0.0125 0.0338 0.0516
Echinococcus granulosus tubulin subunit TubB 0.0902 0.2816 0.4301
Toxoplasma gondii Zn-containing alcohol dehydrogenase 0.0062 0.0137 0.0355
Wolbachia endosymbiont of Brugia malayi 3-oxoacyl-ACP synthase 0.025 0.0736 0.8882
Plasmodium vivax delta tubulin, putative 0.0278 0.0826 0.2256
Mycobacterium leprae Probable polyketide synthase Pks1 0.1056 0.3308 0.7057
Echinococcus granulosus lysine specific demethylase 6a 0.004 0.0069 0.0105
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0019 0.0001 0.0001
Plasmodium vivax histone acetyltransferase GCN5, putative 0.0043 0.0077 0.0207
Echinococcus multilocularis tubulin alpha chain 0.0902 0.2816 0.2816
Mycobacterium leprae Conserved hypothetical protein 0.018 0.0513 0.106
Leishmania major aldo/keto reductase, putative,aldo/keto reductase family-like protein 0.0073 0.0174 0.0456
Schistosoma mansoni topbp1 0.0027 0.0025 0.0038
Echinococcus granulosus aldo keto reductase family 1 member B4 0.0253 0.0747 0.114
Trichomonas vaginalis tubulin beta chain, putative 0.0902 0.2816 0.7702
Trichomonas vaginalis lipid A export ATP-binding/permease protein msba, putative 0.0033 0.0044 0.0109
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0041 0.007 0.0117
Schistosoma mansoni tubulin subunit alpha 0.0278 0.0826 0.1261
Schistosoma mansoni mixed-lineage leukemia protein mll 0.003 0.0037 0.0057
Brugia malayi beta-tubulin, identical 0.1165 0.3655 0.6141
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.0041 0.007 0.0107
Loa Loa (eye worm) ATP-dependent DNA helicase 0.0028 0.0029 0.0055
Schistosoma mansoni chromodomain helicase DNA binding protein 0.002 0.0003 0.0005
Trypanosoma cruzi DNA polymerase kappa, putative 0.0059 0.0128 0.0331
Entamoeba histolytica tubulin alpha-1 chain 0.0902 0.2816 0.77
Brugia malayi hypothetical protein 0.0073 0.0174 0.0292
Echinococcus granulosus voltage gated potassium channel subunit 0.0073 0.0174 0.0265
Trypanosoma brucei RNA helicase, putative 0.0107 0.028 0.0756
Loa Loa (eye worm) hypothetical protein 0.0253 0.0747 0.1417
Brugia malayi acetyltransferase, GNAT family protein 0.0136 0.0373 0.0626
Leishmania major cytochrome p450-like protein 0.0038 0.0061 0.0148
Echinococcus granulosus Jumonji AT rich interactive domain 1B 0.0049 0.0095 0.0145
Echinococcus granulosus arachidonate 5 lipoxygenase 0.0116 0.0308 0.0471
Echinococcus multilocularis 3 hydroxyacyl coenzyme A dehydrogenase type 2 0.006 0.0131 0.0131
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.0041 0.007 0.0124
Mycobacterium ulcerans non-ribosomal peptide synthetase 0.0101 0.0264 0.0525
Echinococcus granulosus lipoxygenase domain containing protein 0.0019 0.0002 0.0002
Toxoplasma gondii poly(ADP-ribose) polymerase catalytic domain-containing protein 0.0781 0.243 0.6642
Echinococcus granulosus poly (ADP ribose) polymerase 0.0069 0.0161 0.0246
Loa Loa (eye worm) MH2 domain-containing protein 0.0356 0.1076 0.2041
Trypanosoma brucei mitochondrial DNA polymerase beta 0.0295 0.0882 0.2403
Brugia malayi Phosphopantetheine attachment site family protein 0.01 0.026 0.0437
Mycobacterium ulcerans NADPH quinone oxidoreductase FadB4 0.0062 0.0137 0.0253
Entamoeba histolytica P-glycoprotein-5 0.0033 0.0044 0.01
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0095 0.0243 0.0409
Trichomonas vaginalis multidrug resistance protein 1, 2, putative 0.0033 0.0044 0.0109
Echinococcus granulosus PHD finger protein rhinoceros 0.0027 0.0027 0.0042
Echinococcus granulosus poly adp ribose polymerase 2 0.0553 0.1704 0.2602
Brugia malayi Muscleblind-like protein 0.0305 0.0912 0.1532
Plasmodium vivax tubulin gamma chain, putative 0.064 0.198 0.5416
Schistosoma mansoni ran 0.0021 0.0008 0.0011
Leishmania major hypothetical protein, conserved 0.004 0.0069 0.0168
Brugia malayi Ets-domain containing protein 0.0068 0.0157 0.0264
Mycobacterium ulcerans malonyl CoA-acyl carrier protein transacylase FabD 0.0063 0.014 0.026
Trypanosoma cruzi zeta tubulin, putative 0.0278 0.0826 0.2244
Echinococcus multilocularis aldo keto reductase family 1, member B4 0.0253 0.0747 0.0747
Echinococcus granulosus lysine specific demethylase 5A 0.016 0.0449 0.0685
Leishmania major alpha tubulin 0.0902 0.2816 0.77
Entamoeba histolytica phosphofructokinase, putative 0.0106 0.0279 0.0744
Trichomonas vaginalis tubulin epsilon chain, putative 0.0278 0.0826 0.225
Leishmania major tyrosyl-DNA phosphodiesterase 1 0.007 0.0164 0.0428
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0108 0.0284 0.0476
Schistosoma mansoni protein phosphatase 2C 0.004 0.0069 0.0105
Schistosoma mansoni aldehyde dehydrogenase 0.0131 0.0358 0.0547
Brugia malayi oxidoreductase, zinc-binding dehydrogenase family protein 0.1885 0.5951 1
Loa Loa (eye worm) DR-78 0.0019 0.0001 0.0002
Mycobacterium ulcerans extragenic suppressor protein SuhB 0.0041 0.0069 0.0108
Mycobacterium tuberculosis Phenolpthiocerol synthesis type-I polyketide synthase PpsD 0.0995 0.3111 0.6635
Echinococcus granulosus mitogen activated protein kinase 0.1068 0.3347 0.5111
Loa Loa (eye worm) blistered cuticle protein 3 0.0034 0.0049 0.0093
Echinococcus multilocularis tissue type plasminogen activator 0.0022 0.001 0.001
Loa Loa (eye worm) hypothetical protein 0.0019 0.0001 0.0002
Trichomonas vaginalis ABC transporter, putative 0.0033 0.0044 0.0109
Schistosoma mansoni hypothetical protein 0.0095 0.0243 0.0371
Trichomonas vaginalis conserved hypothetical protein 0.004 0.0067 0.0171
Loa Loa (eye worm) phosphofructokinase 0.0106 0.0279 0.0529
Mycobacterium leprae Probable multifunctional mycocerosic acid synthase membrane associated enzyme Mas 0.1056 0.3308 0.7057
Trypanosoma brucei DNA polymerase kappa, putative 0.0059 0.0128 0.0339
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0042 0.0072 0.0178
Loa Loa (eye worm) inositol-1 0.0041 0.0069 0.0132
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.0041 0.007 0.0107
Toxoplasma gondii PHD-finger domain-containing protein 0.0027 0.0027 0.0054
Entamoeba histolytica alcohol dehydrogenase, putative 0.0073 0.0174 0.0456
Trypanosoma brucei tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.007 0.0164 0.0436
Leishmania major beta tubulin 0.1165 0.3655 1
Brugia malayi beta-NAC-like protein 0.0065 0.0146 0.0245
Brugia malayi oxidoreductase, aldo/keto reductase family protein 0.0253 0.0747 0.1255
Brugia malayi Ets-domain containing protein 0.0068 0.0157 0.0264
Loa Loa (eye worm) acyl carrier protein 0.01 0.026 0.0494
Entamoeba histolytica tubulin alpha chain, putative 0.0902 0.2816 0.77
Plasmodium vivax oxidoreductase, aldo/keto reductase domain containing protein 0.0073 0.0174 0.0471
Brugia malayi MH2 domain containing protein 0.0024 0.0017 0.0029
Onchocerca volvulus 0.0253 0.0747 0.132
Leishmania major beta tubulin 0.1165 0.3655 1
Schistosoma mansoni blooms syndrome DNA helicase 0.0026 0.0023 0.0035
Echinococcus granulosus Transcription factor JmjC domain containing protein 0.0208 0.0603 0.0921
Mycobacterium ulcerans thioesterase 0.0829 0.2583 0.55
Echinococcus multilocularis GPCR, family 2 0.0095 0.0243 0.0243
Trichomonas vaginalis aldo-keto reductase, putative 0.0253 0.0747 0.2034
Mycobacterium ulcerans phenolpthiocerol synthesis type-I polyketide synthase PpsD 0.0995 0.3111 0.6635
Loa Loa (eye worm) hypothetical protein 0.0027 0.0025 0.0048
Entamoeba histolytica tubulin family protein 0.1165 0.3655 1
Plasmodium falciparum importin beta, putative 0.0056 0.0118 0.0319
Brugia malayi oxidoreductase, zinc-binding dehydrogenase family protein 0.0062 0.0137 0.023
Trypanosoma cruzi DNA polymerase beta thumb, putative 0.0042 0.0072 0.0178
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0055 0.0116 0.0177
Giardia lamblia Alpha-tubulin 0.0902 0.2816 0.77
Brugia malayi MH1 domain containing protein 0.0024 0.0017 0.0029
Mycobacterium tuberculosis Polyketide synthetase MbtC (polyketide synthase) 0.0342 0.103 0.2169
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.0041 0.007 0.0107
Loa Loa (eye worm) glutaminase 2 0.0273 0.081 0.1537
Mycobacterium leprae PHENOLPTHIOCEROL SYNTHESIS TYPE-I POLYKETIDE SYNTHASE PPSB 0.08 0.2492 0.5305
Trypanosoma brucei oxidoreductase, putative 0.0062 0.0137 0.0363
Schistosoma mansoni alcohol dehydrogenase 0.0062 0.0137 0.0209
Schistosoma mansoni jumonji/arid domain-containing protein 0.016 0.0449 0.0685
Trichomonas vaginalis conserved hypothetical protein 0.0027 0.0025 0.0057
Brugia malayi AMP-binding enzyme family protein 0.0937 0.2926 0.4917
Schistosoma mansoni alpha tubulin 0.0902 0.2816 0.4301
Brugia malayi Protein kinase domain containing protein 0.0022 0.001 0.0018
Leishmania major zeta tubulin, putative 0.0278 0.0826 0.2244
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.0041 0.007 0.0107
Echinococcus granulosus aldo keto reductase 0.0253 0.0747 0.114
Trichomonas vaginalis CMGC family protein kinase 0.1068 0.3347 0.9156
Onchocerca volvulus 0.0262 0.0775 0.1371
Mycobacterium ulcerans peptide synthetase Nrp (peptide synthase) 0.0108 0.0284 0.0567
Echinococcus granulosus dna polymerase kappa 0.0059 0.0128 0.0196
Mycobacterium tuberculosis P-hydroxybenzoyl-AMP ligase FadD22 0.0108 0.0284 0.0567
Trypanosoma cruzi poly(ADP-ribose) polymerase, putative 0.0553 0.1704 0.465
Trypanosoma cruzi DNA repair protein, putative 0.0058 0.0126 0.0324
Trichomonas vaginalis alcohol dehydrogenase, putative 0.0062 0.0137 0.0363
Trypanosoma brucei ferric reductase transmembrane protein, putative 0.0034 0.0049 0.0122
Loa Loa (eye worm) hypothetical protein 0.0027 0.0025 0.0048
Chlamydia trachomatis ABC transporter ATP binding protein/permease 0.0033 0.0044 0.031
Schistosoma mansoni ran 0.0021 0.0008 0.0011
Chlamydia trachomatis DNA ligase 0.0027 0.0025 0.0046
Loa Loa (eye worm) glutamate-cysteine ligase modifier subunit 0.0073 0.0174 0.0329
Mycobacterium ulcerans acyl carrier protein 0.01 0.026 0.0518
Schistosoma mansoni multidrug resistance protein 0.0033 0.0044 0.0067
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative 0.0039 0.0064 0.0164
Trypanosoma cruzi beta tubulin, putative 0.1165 0.3655 1
Leishmania major beta tubulin 0.1165 0.3655 1
Schistosoma mansoni chromosome transmission fidelity factor 0.0027 0.0025 0.0038
Toxoplasma gondii 6-phosphofructokinase 0.0029 0.0032 0.0066
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0041 0.007 0.0117
Schistosoma mansoni intermediate filament proteins 0.0027 0.0026 0.004
Echinococcus multilocularis ATP binding cassette subfamily B (MDR:TAP) 0.0033 0.0044 0.0044
Echinococcus granulosus mitochondrial trans 2 enoyl coenzyme A reductase 0.0062 0.0137 0.0209
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.003 0.0036 0.0087
Trypanosoma cruzi zeta tubulin, putative 0.0278 0.0826 0.2244
Leishmania major DNA polymerase eta, putative 0.0035 0.0052 0.0122
Echinococcus granulosus retinoic acid receptor rxr beta a 0.0041 0.007 0.0107
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0046 0.0087 0.0133
Mycobacterium leprae cell division protein FtsZ 0.0278 0.0826 0.1731
Trichomonas vaginalis alcohol dehydrogenase, putative 0.0062 0.0137 0.0363
Echinococcus multilocularis tubulin alpha 1C chain 0.0902 0.2816 0.2816
Schistosoma mansoni zinc binding dehydrogenase 0.0062 0.0137 0.0209
Schistosoma mansoni Tr4/Tr2 (homologue) 0.0041 0.007 0.0107
Loa Loa (eye worm) hypothetical protein 0.0056 0.0118 0.0224
Trypanosoma brucei ATP-dependent DEAD/H DNA helicase recQ, putative 0.0031 0.0037 0.009
Trichomonas vaginalis importin beta-1, putative 0.0045 0.0084 0.0219
Treponema pallidum diphosphate--fructose-6-phosphate 1-phosphotransferase 0.0029 0.0032 0.012
Echinococcus multilocularis aldo keto reductase family 1, member B4 0.0253 0.0747 0.0747
Trichomonas vaginalis multidrug resistance protein 1, 2, putative 0.0033 0.0044 0.0109
Mycobacterium tuberculosis Conserved hypothetical protein 0.0033 0.0045 0.0056
Schistosoma mansoni 6-phosphofructokinase 0.0106 0.0279 0.0426
Trypanosoma cruzi hypothetical protein, conserved 0.0027 0.0025 0.0048
Loa Loa (eye worm) CHromoDomain protein family member 0.002 0.0003 0.0006
Echinococcus granulosus mixed lineage leukemia protein mll 0.0022 0.0009 0.0013
Loa Loa (eye worm) hypothetical protein 0.0041 0.007 0.0133
Echinococcus granulosus RUN 0.0019 0.0002 0.0002
Trichomonas vaginalis tubulin beta-1 chain, putative 0.0278 0.0826 0.225
Trypanosoma brucei alpha tubulin, putative 0.0362 0.1094 0.2986
Echinococcus multilocularis GA binding protein alpha chain 0.0068 0.0157 0.0157
Echinococcus granulosus multidrug resistance protein 1 0.0023 0.0013 0.002
Echinococcus granulosus nuclear receptor nhr 48 0.0019 0.0001 0.0002
Brugia malayi oxidoreductase, zinc-binding dehydrogenase family protein 0.0062 0.0137 0.023
Leishmania major alpha tubulin 0.0902 0.2816 0.77
Loa Loa (eye worm) ICD-1 protein 0.0065 0.0146 0.0277
Brugia malayi Nuclear hormone receptor E75 0.0019 0.0001 0.0002
Echinococcus multilocularis cpg binding protein 0.009 0.0227 0.0227
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.0118 0.0317 0.0317
Giardia lamblia Delta tubulin 0.0278 0.0826 0.2244
Trypanosoma brucei cytochrome P450, putative 0.0038 0.0061 0.0156
Echinococcus multilocularis PHD finger protein rhinoceros 0.0027 0.0027 0.0027
Plasmodium falciparum tubulin delta chain, putative 0.0278 0.0826 0.2256
Echinococcus granulosus tubulin alpha 1C chain 0.0902 0.2816 0.4301
Echinococcus granulosus bloom syndrome protein 0.004 0.0068 0.0104
Schistosoma mansoni terminal deoxycytidyl transferase 0.0033 0.0045 0.0069
Echinococcus granulosus Tubulin alpha 1 chain 0.0902 0.2816 0.4301
Mycobacterium leprae PROBABLE OXIDOREDUCTASE 0.0253 0.0747 0.1561
Trichomonas vaginalis ABC transporter, putative 0.0033 0.0044 0.0109
Echinococcus multilocularis methyl CpG binding domain protein 2 0.0031 0.004 0.004
Schistosoma mansoni nuclear hormone receptor 0.0041 0.007 0.0107
Mycobacterium tuberculosis Conserved protein 0.0073 0.0174 0.0332
Leishmania major hypothetical protein, conserved 0.0028 0.003 0.0062
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0073 0.0174 0.0174
Entamoeba histolytica P-glycoprotein-2 0.0033 0.0044 0.01
Entamoeba histolytica alcohol dehydrogenase, putative 0.0073 0.0174 0.0456
Schistosoma mansoni rab geranylgeranyl transferase alpha subunit 0.0033 0.0045 0.0069
Toxoplasma gondii beta-ketoacyl synthase, N-terminal domain-containing protein 0.0645 0.1997 0.5456
Trichomonas vaginalis ATP-binding cassette transporter, putative 0.0033 0.0044 0.0109
Brugia malayi Methyltransferase-like protein 4 0.03 0.0895 0.1504
Echinococcus multilocularis ATP binding cassette sub family G 0.0061 0.0135 0.0135
Mycobacterium ulcerans transmembrane ABC transporter ATP-binding protein 0.0061 0.0135 0.0249
Loa Loa (eye worm) hypothetical protein 0.0019 0.0001 0.0002
Loa Loa (eye worm) acetyltransferase 0.0136 0.0373 0.0707
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0175 0.0496 0.0758
Echinococcus multilocularis multidrug resistance protein 1 0.0033 0.0044 0.0044
Loa Loa (eye worm) tubulin alpha 2 0.0624 0.193 0.3662
Brugia malayi ecdysteroid receptor 0.0041 0.007 0.0117
Loa Loa (eye worm) hypothetical protein 0.0022 0.0009 0.0016
Mycobacterium leprae PHENOLPTHIOCEROL SYNTHESIS TYPE-I POLYKETIDE SYNTHASE PPSC 0.1056 0.3308 0.7057
Mycobacterium ulcerans polyketide synthase MbtC 0.025 0.0736 0.1538
Trichomonas vaginalis tubulin gamma chain, putative 0.064 0.198 0.5413
Echinococcus granulosus dnaJ subfamily B 0.1164 0.365 0.5574
Loa Loa (eye worm) hypothetical protein 0.0062 0.0137 0.026
Loa Loa (eye worm) hypothetical protein 0.0062 0.0137 0.026
Trichomonas vaginalis alcohol dehydrogenase, putative 0.0073 0.0174 0.0464
Mycobacterium leprae PROBABLE POLYKETIDE BETA-KETOACYL SYNTHASE PKS4 0.0153 0.0426 0.0874
Trypanosoma brucei alpha tubulin 0.0902 0.2816 0.7702
Trypanosoma cruzi mitochondrial DNA polymerase beta, putative 0.0295 0.0882 0.2397
Schistosoma mansoni hypothetical protein 0.0027 0.0027 0.0042
Mycobacterium tuberculosis Probable polyketide synthase Pks17 0.0243 0.0715 0.1493
Loa Loa (eye worm) PHD-finger family protein 0.0027 0.0027 0.0052
Schistosoma mansoni aminoadipate-semialdehyde dehydrogenase 0.0091 0.0231 0.0353
Mycobacterium tuberculosis Peptide synthetase MbtF (peptide synthase) 0.0108 0.0284 0.0567
Loa Loa (eye worm) hypothetical protein 0.0027 0.0025 0.0047
Entamoeba histolytica myo-inositol monophosphatase, putative 0.0041 0.0069 0.017
Mycobacterium tuberculosis Probable alcohol dehydrogenase Adh 0.0062 0.0137 0.0253
Trichomonas vaginalis tubulin, putative 0.0278 0.0826 0.225
Schistosoma mansoni tubulin subunit beta 0.1165 0.3655 0.5582
Loa Loa (eye worm) hypothetical protein 0.0079 0.019 0.0361
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.0039 0.0064 0.0064
Echinococcus granulosus cpg binding protein 0.009 0.0227 0.0346
Loa Loa (eye worm) jmjC domain-containing protein 0.004 0.0069 0.013
Brugia malayi NADH-dependent xylose reductase 0.0073 0.0174 0.0292
Echinococcus granulosus phd:f box containing protein 0.004 0.0069 0.0105
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.0041 0.007 0.0133
Trypanosoma cruzi cytochrome P450, putative 0.0038 0.0061 0.0148
Echinococcus granulosus aldo keto reductase family 1, member B4 0.0073 0.0174 0.0265
Echinococcus granulosus chromobox protein 1 0.0071 0.0166 0.0254
Brugia malayi N-terminal motif family protein 0.0198 0.0572 0.0962
Plasmodium vivax multidrug resistance protein 1, putative 0.0033 0.0044 0.0116
Giardia lamblia Alpha-tubulin 0.0902 0.2816 0.77
Trypanosoma brucei DNA polymerase kappa, putative 0.0059 0.0128 0.0339
Echinococcus multilocularis nuclear receptor nhr 48 0.0019 0.0001 0.0001
Plasmodium falciparum phd finger protein, putative 0.0027 0.0027 0.0071
Toxoplasma gondii aldehyde dehydrogenase 0.0131 0.0358 0.0962
Loa Loa (eye worm) jmjC domain-containing protein 0.016 0.0449 0.0851
Schistosoma mansoni RAR-like nuclear receptor 0.0041 0.007 0.0107
Schistosoma mansoni acetyl-CoA C-acetyltransferase 0.0046 0.0088 0.0134
Mycobacterium ulcerans oxidoreductase 0.0062 0.0137 0.0253
Entamoeba histolytica hypothetical protein 0.0073 0.0174 0.0457
Entamoeba histolytica transcription factor BTF3, putative 0.0065 0.0146 0.0379
Mycobacterium ulcerans multifunctional mycocerosic acid synthase membrane-associated Mas 0.1056 0.3308 0.7057
Leishmania major beta tubulin 0.1165 0.3655 1
Echinococcus multilocularis Tubulin beta 2C chain 0.1165 0.3655 0.3655
Trypanosoma brucei DNA polymerase beta thumb, putative 0.0042 0.0072 0.0186
Mycobacterium ulcerans 6-phosphofructokinase 0.0106 0.0279 0.0558
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.003 0.0036 0.0087
Mycobacterium leprae PHENOLPTHIOCEROL SYNTHESIS TYPE-I POLYKETIDE SYNTHASE PPSD 0.0995 0.3111 0.6635
Trichomonas vaginalis tubulin gamma chain, putative 0.1165 0.3655 1
Schistosoma mansoni 3-oxoacyl-[ACP] synthase 0.025 0.0736 0.1124
Mycobacterium ulcerans zinc-dependent alcohol dehydrogenase AdhE2 0.0062 0.0137 0.0253
Echinococcus multilocularis Jumonji, AT rich interactive domain 1B 0.0049 0.0095 0.0095
Trypanosoma brucei BRCA1 C Terminus (BRCT) domain containing protein, putative 0.0027 0.0025 0.0057
Leishmania major delta tubulin, putative 0.0278 0.0826 0.2244
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0066 0.0151 0.023
Loa Loa (eye worm) PHD-finger family protein 0.0038 0.0061 0.0117
Echinococcus multilocularis muscleblind protein 1 0.0305 0.0912 0.0912
Schistosoma mansoni smad1 5 8 and 0.0024 0.0017 0.0027
Mycobacterium tuberculosis Meromycolate extension acyl carrier protein AcpM 0.01 0.026 0.0518
Onchocerca volvulus 0.0031 0.0039 0.007
Schistosoma mansoni [ACP] S-malonyltransferase 0.0063 0.014 0.0214
Echinococcus multilocularis TGF beta signal transducer SmadC 0.0024 0.0017 0.0017
Toxoplasma gondii hypothetical protein 0.0048 0.0092 0.0231
Entamoeba histolytica P-glycoprotein 5, putative 0.0033 0.0044 0.01
Brugia malayi hypothetical protein 0.0019 0.0002 0.0003
Toxoplasma gondii alpha-tubulin I, putative 0.0902 0.2816 0.77
Brugia malayi Tubulin beta chain 0.0278 0.0826 0.1388
Entamoeba histolytica acetyltransferase, GNAT family 0.0035 0.0053 0.0124
Trichomonas vaginalis phosphofructokinase, putative 0.0106 0.0279 0.0752
Loa Loa (eye worm) hypothetical protein 0.004 0.0069 0.013
Echinococcus multilocularis snurportin 1 0.0597 0.1843 0.1843
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.0028 0.0029 0.006
Leishmania major mitochondrial DNA polymerase beta 0.0295 0.0882 0.2397
Trichomonas vaginalis conserved hypothetical protein 0.0091 0.023 0.0619
Trichomonas vaginalis DNA polymerase IV / kappa, putative 0.0059 0.0128 0.0339
Loa Loa (eye worm) hypothetical protein 0.0902 0.2816 0.5342
Plasmodium falciparum cysteine repeat modular protein 1 0.0022 0.001 0.0024
Toxoplasma gondii acyl transferase domain-containing protein 0.0063 0.014 0.0364
Trypanosoma cruzi tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.007 0.0164 0.0428
Echinococcus multilocularis smad 0.0024 0.0017 0.0017
Trypanosoma cruzi PAB1-binding protein , putative 0.0025 0.0018 0.0029
Loa Loa (eye worm) hypothetical protein 0.0019 0.0001 0.0002
Entamoeba histolytica hypothetical protein 0.0026 0.0022 0.0039
Echinococcus granulosus multidrug resistance protein 1 0.0033 0.0044 0.0067
Toxoplasma gondii tubulin/FtsZ family, GTPase domain-containing protein 0.0278 0.0826 0.2244
Echinococcus granulosus transcription factor Dp 1 0.0041 0.0069 0.0106
Trypanosoma cruzi aldo/keto reductase, putative 0.0253 0.0747 0.2027
Entamoeba histolytica tubulin gamma chain 0.064 0.198 0.5409
Trypanosoma brucei beta tubulin 0.1165 0.3655 1
Trichomonas vaginalis dihydrodiol dehydrogenase, putative 0.0253 0.0747 0.2034
Trypanosoma brucei DNA polymerase kappa, putative 0.0059 0.0128 0.0339
Loa Loa (eye worm) tubulin gamma chain 0.064 0.198 0.3757
Schistosoma mansoni thyroid hormone receptor 0.0041 0.007 0.0107
Trypanosoma brucei DNA polymerase kappa, putative 0.0059 0.0128 0.0339
Giardia lamblia Beta tubulin 0.1165 0.3655 1
Echinococcus granulosus tyrosyl DNA phosphodiesterase 1 0.007 0.0164 0.025
Echinococcus multilocularis tubulin, beta 4A class IVa 0.1165 0.3655 0.3655
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.1068 0.3347 0.9155
Leishmania major ATP-dependent DEAD/H DNA helicase recQ, putative 0.0031 0.0037 0.0082
Leishmania major beta tubulin 0.1165 0.3655 1
Trichomonas vaginalis chromobox protein, putative 0.0043 0.0076 0.0197
Loa Loa (eye worm) hypothetical protein 0.012 0.0322 0.0611
Brugia malayi jmjC domain containing protein 0.016 0.0449 0.0754
Schistosoma mansoni lipoxygenase 0.0116 0.0308 0.0471
Trypanosoma brucei DNA polymerase IV, putative 0.0059 0.0128 0.0339
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.0041 0.007 0.007
Brugia malayi nuclear hormone receptor family member nhr-6 0.0019 0.0001 0.0002
Loa Loa (eye worm) hypothetical protein 0.0058 0.0126 0.0238
Trichomonas vaginalis cat eye syndrome critical region protein 2, cscr2, putative 0.0043 0.0077 0.0199
Echinococcus granulosus beta tubulin 0.1165 0.3655 0.5582
Echinococcus multilocularis ATP binding cassette sub family B 0.0032 0.0041 0.0041
Brugia malayi Bloom's syndrome protein homolog 0.004 0.0068 0.0115
Loa Loa (eye worm) hypothetical protein 0.0027 0.0027 0.005
Echinococcus granulosus ATP binding cassette sub family G 0.0061 0.0135 0.0206
Loa Loa (eye worm) hypothetical protein 0.004 0.0069 0.013
Schistosoma mansoni importin beta-1 0.0056 0.0118 0.018
Onchocerca volvulus 0.0025 0.0019 0.0034
Toxoplasma gondii 4'-phosphopantetheinyl transferase domain-containing protein 0.0026 0.0022 0.0039
Echinococcus granulosus aldo keto reductase family 1 member B4 0.0253 0.0747 0.114
Loa Loa (eye worm) hypothetical protein 0.0066 0.0151 0.0286
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0055 0.0116 0.0177
Schistosoma mansoni pol-related 0.0253 0.0747 0.114
Echinococcus multilocularis dnaJ subfamily B 0.1164 0.365 0.365
Trypanosoma brucei prostaglandin f synthase 0.0253 0.0747 0.2033
Trichomonas vaginalis ATP-binding cassette transporter, putative 0.0033 0.0044 0.0109
Leishmania major beta tubulin 0.1165 0.3655 1
Echinococcus multilocularis AMP dependent ligase 0.0101 0.0264 0.0264
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0041 0.0069 0.0178
Trypanosoma cruzi epsilon tubulin, putative 0.064 0.198 0.5409
Mycobacterium leprae PROBABLE THIOESTERASE TESA 0.0829 0.2583 0.55
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0022 0.0009 0.0013
Echinococcus granulosus Smad4 0.0024 0.0017 0.0027
Mycobacterium ulcerans hypothetical protein 0.0073 0.0174 0.0332
Plasmodium vivax replication factor C subunit 1, putative 0.0027 0.0025 0.0065
Trichomonas vaginalis lipid A export ATP-binding/permease protein msba, putative 0.0033 0.0044 0.0109
Echinococcus granulosus tubulin alpha 3 chain 0.0902 0.2816 0.4301
Schistosoma mansoni acyl carrier protein 0.01 0.026 0.0398
Trypanosoma cruzi ferric reductase transmembrane protein, putative 0.0034 0.0049 0.0114
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0026 0.0024 0.0037
Trypanosoma brucei isocitrate dehydrogenase, putative 0.0032 0.004 0.0098
Leishmania major epsilon tubulin, putative 0.064 0.198 0.5409
Loa Loa (eye worm) nuclear hormone receptor-like 1 0.0022 0.0009 0.0016
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0035 0.005 0.0117
Echinococcus multilocularis beta tubulin 0.1165 0.3655 0.3655
Brugia malayi Bromodomain containing protein 0.0074 0.0176 0.0295
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0019 0.0001 0.0002
Mycobacterium ulcerans 4'-phosphopantetheinyl transferase 0.0026 0.0022 0.0006
Plasmodium falciparum aldehyde reductase, putative 0.0073 0.0174 0.0471
Echinococcus multilocularis ATP binding cassette subfamily B (MDR:TAP) 0.0033 0.0044 0.0044
Loa Loa (eye worm) hypothetical protein 0.0033 0.0044 0.0083
Leishmania major zinc-binding dehydrogenase-like protein 0.0062 0.0137 0.0355
Brugia malayi hypothetical protein 0.0019 0.0001 0.0002
Brugia malayi Beta-ketoacyl synthase, N-terminal domain containing protein 0.025 0.0736 0.1237
Toxoplasma gondii tubulin/FtsZ family, GTPase domain-containing protein 0.0278 0.0826 0.2244
Loa Loa (eye worm) hypothetical protein 0.0019 0.0001 0.0002
Trichomonas vaginalis ABC transporter, putative 0.0033 0.0044 0.0109
Giardia lamblia Methyltransferase like 2 0.03 0.0895 0.2434
Loa Loa (eye worm) hypothetical protein 0.0041 0.007 0.0133
Brugia malayi Tubulin alpha chain 0.0902 0.2816 0.4732
Schistosoma mansoni lipoxygenase 0.0081 0.0198 0.0302
Brugia malayi Nuclear hormone receptor-like 1 0.0041 0.007 0.0117
Toxoplasma gondii aldo-keto reductase 0.0073 0.0174 0.0456
Mycobacterium ulcerans polyketide synthase 0.0995 0.3111 0.6635
Schistosoma mansoni 6-phosphofructokinase 0.0106 0.0279 0.0426
Echinococcus granulosus histone acetyltransferase KAT2B 0.0128 0.0347 0.053
Trypanosoma cruzi NADP-dependent alcohol hydrogenase, putative 0.0062 0.0137 0.0355
Leishmania major beta tubulin 0.1165 0.3655 1
Echinococcus multilocularis poly (ADP ribose) polymerase 0.016 0.0451 0.0451
Trypanosoma cruzi JmjC domain, hydroxylase, putative 0.004 0.0069 0.0168
Trypanosoma cruzi mitogen activated protein kinase 4, putative 0.1068 0.3347 0.9155
Mycobacterium tuberculosis Probable peptide synthetase Nrp (peptide synthase) 0.0108 0.0284 0.0567
Mycobacterium tuberculosis Acyl carrier protein (ACP) MbtL 0.01 0.026 0.0518
Trypanosoma cruzi ATP-binding cassette protein, putative 0.0061 0.0135 0.035
Echinococcus multilocularis Tubulin beta 2C chain 0.1165 0.3655 0.3655
Brugia malayi Pre-SET motif family protein 0.023 0.0675 0.1134
Entamoeba histolytica hypothetical protein 0.0073 0.0174 0.0457
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.014 0.0386 0.1037
Brugia malayi glutaminase DH11.1 0.0273 0.081 0.1361
Trichomonas vaginalis conserved hypothetical protein 0.0065 0.0146 0.0388
Loa Loa (eye worm) hypothetical protein 0.0205 0.0595 0.1129
Loa Loa (eye worm) jmjC domain-containing protein 0.0057 0.012 0.0228
Loa Loa (eye worm) ImpB/MucB/SamB family protein 0.0033 0.0045 0.0086
Echinococcus multilocularis jumonji domain containing protein 0.0038 0.0062 0.0062
Brugia malayi Pax transcription activation domain interacting protein 0.0027 0.0025 0.0042
Schistosoma mansoni tyrosyl-DNA phosphodiesterase 0.007 0.0164 0.025
Loa Loa (eye worm) hypothetical protein 0.0027 0.0025 0.0048
Toxoplasma gondii 4'-phosphopantetheinyl transferase superfamily protein 0.0026 0.0022 0.0039
Schistosoma mansoni inositol monophosphatase 0.0041 0.0069 0.0106
Entamoeba histolytica hypothetical protein 0.0073 0.0174 0.0457
Leishmania major beta tubulin 0.1165 0.3655 1
Echinococcus granulosus intermediate filament protein 0.0027 0.0026 0.004
Trypanosoma brucei epsilon tubulin 0.064 0.198 0.5412
Mycobacterium tuberculosis Hypothetical protein 0.03 0.0895 0.188
Loa Loa (eye worm) hypothetical protein 0.0019 0.0001 0.0002
Onchocerca volvulus 0.0082 0.02 0.0354
Loa Loa (eye worm) hypothetical protein 0.0198 0.0572 0.1086
Loa Loa (eye worm) oxidoreductase 0.0253 0.0747 0.1417
Loa Loa (eye worm) hypothetical protein 0.0153 0.0426 0.0809
Loa Loa (eye worm) hypothetical protein 0.0071 0.0166 0.0315
Schistosoma mansoni topbp1 0.0027 0.0025 0.0038
Schistosoma mansoni nuclear hormone receptor 0.0019 0.0001 0.0002
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.003 0.0036 0.0087
Echinococcus granulosus jumonji domain containing protein 0.0038 0.0062 0.0094
Plasmodium vivax malonyl CoA-acyl carrier protein transacylase precursor, putative 0.0063 0.014 0.0379
Toxoplasma gondii isocitrate dehydrogenase 0.0032 0.004 0.009
Trypanosoma brucei DNA polymerase kappa, putative 0.0036 0.0056 0.014
Echinococcus multilocularis lamin dm0 0.0027 0.0026 0.0026
Schistosoma mansoni tubulin subunit beta 0.1165 0.3655 0.5582
Toxoplasma gondii quinone oxidoreductase, putative 0.0062 0.0137 0.0355
Mycobacterium ulcerans non-ribosomal peptide synthetase MbtF 0.0108 0.0284 0.0567
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0026 0.0024 0.0024
Echinococcus multilocularis ATP binding cassette sub family G 0.0061 0.0135 0.0135
Echinococcus granulosus FTZ F1 alpha 0.0041 0.007 0.0107
Brugia malayi Inositol-1 0.0041 0.0069 0.0117
Echinococcus multilocularis Malonyl coenzyme A acyl carrier protein transacylase 0.0063 0.014 0.014
Loa Loa (eye worm) cytochrome P450 family protein 0.0038 0.0061 0.0117
Brugia malayi Nuclear hormone receptor family member nhr-3 0.0041 0.007 0.0117
Plasmodium vivax 6-phosphofructokinase, putative 0.0029 0.0032 0.0082
Plasmodium falciparum ABC transporter G family member 2 0.0061 0.0135 0.0365
Trypanosoma cruzi transcription factor btf3, putative 0.0065 0.0146 0.0379
Brugia malayi tubulin alpha chain - mouse 0.0902 0.2816 0.4732
Brugia malayi hypothetical protein 0.0022 0.0009 0.0014
Loa Loa (eye worm) hypothetical protein 0.0062 0.0137 0.026
Mycobacterium tuberculosis Phenyloxazoline synthase MbtB (phenyloxazoline synthetase) 0.0937 0.2926 0.6238
Echinococcus multilocularis ATP binding cassette sub family G 0.0061 0.0135 0.0135
Echinococcus granulosus Tubulin beta 2C chain 0.1165 0.3655 0.5582
Loa Loa (eye worm) hypothetical protein 0.0019 0.0002 0.0003
Toxoplasma gondii ATPase, AAA family protein 0.0027 0.0025 0.0049
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.0041 0.007 0.007
Trypanosoma cruzi mitogen activated protein kinase 2, putative 0.1068 0.3347 0.9155
Echinococcus multilocularis musashi 0.0027 0.0026 0.0026
Echinococcus granulosus Malonyl coenzyme A acyl carrier protein transacylase 0.0063 0.014 0.0214
Plasmodium vivax ABC transporter G family member 2, putative 0.0061 0.0135 0.0365
Trypanosoma brucei alpha tubulin 0.0902 0.2816 0.7702
Giardia lamblia Kinase, CMGC MAPK 0.1068 0.3347 0.9155
Echinococcus multilocularis lipoxygenase domain containing protein 0.0019 0.0002 0.0002
Trypanosoma brucei aldo-keto reductase, putative 0.0253 0.0747 0.2033
Echinococcus multilocularis transcription factor Dp 1 0.0041 0.0069 0.0069
Trichomonas vaginalis aldo-keto reductase, putative 0.0253 0.0747 0.2034
Schistosoma mansoni ATP-binding cassette sub-family g2 (white protein) (abcg2) 0.0061 0.0135 0.0206
Schistosoma mansoni TGF-beta signal transducer Smad2 0.0024 0.0017 0.0027
Schistosoma mansoni ABC transporter 0.0052 0.0106 0.0161
Plasmodium falciparum basic transcription factor 3b, putative 0.0065 0.0146 0.0395
Echinococcus multilocularis nuclear receptor subfamily 1 group D 0.0022 0.0009 0.0009
Mycobacterium tuberculosis Probable alcohol dehydrogenase AdhA 0.0062 0.0137 0.0253
Loa Loa (eye worm) oxidoreductase 0.0253 0.0747 0.1417
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0041 0.007 0.0117
Loa Loa (eye worm) D-ets-4 DNA binding domain-containing protein 0.0068 0.0157 0.0298
Entamoeba histolytica P-glycoprotein-2 0.0033 0.0044 0.01
Brugia malayi nuclear hormone receptor 0.0041 0.007 0.0117
Brugia malayi ADP-specific Phosphofructokinase/Glucokinase conserved region family protein 0.0063 0.014 0.0235
Brugia malayi Steroid receptor seven-up type 2 0.0041 0.007 0.0117
Brugia malayi orphan nuclear receptor NR2E1 0.0019 0.0001 0.0002
Loa Loa (eye worm) beta-tubulin 0.1165 0.3655 0.6934
Leishmania major beta tubulin 0.1165 0.3655 1
Echinococcus multilocularis geminin 0.0504 0.1546 0.1546
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0032 0.004 0.004
Trichomonas vaginalis conserved hypothetical protein 0.03 0.0895 0.2441
Mycobacterium ulcerans NADP-dependent oxidoreductase 0.0062 0.0137 0.0253
Trypanosoma brucei DNA repair protein, putative 0.0058 0.0126 0.0332
Brugia malayi chromobox protein homolog 3 0.004 0.0067 0.0112
Brugia malayi Tubulin alpha-2 chain 0.0902 0.2816 0.4732
Echinococcus multilocularis nibrin 0.0027 0.0025 0.0025
Loa Loa (eye worm) tubulin alpha 2 0.0624 0.193 0.3662
Schistosoma mansoni hypothetical protein 0.0205 0.0595 0.0909
Schistosoma mansoni Smad4 0.0024 0.0017 0.0027
Trypanosoma brucei zeta tubulin, putative 0.0278 0.0826 0.225
Trichomonas vaginalis tubulin beta chain, putative 0.1165 0.3655 1
Loa Loa (eye worm) hypothetical protein 0.0033 0.0044 0.0083
Entamoeba histolytica acyl-CoA synthetase, putative 0.0101 0.0264 0.0702
Schistosoma mansoni steroid hormone receptor ad4bp 0.0041 0.007 0.0107
Leishmania major 3-oxoacyl-(acyl-carrier protein) reductase, putative 0.006 0.0131 0.0339
Leishmania major basic transcription factor 3a, putative 0.0065 0.0146 0.0379
Trypanosoma brucei epsilon tubulin 0.064 0.198 0.5412
Plasmodium vivax AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0039 0.0064 0.0172
Mycobacterium ulcerans acyl carrier protein 0.01 0.026 0.0518
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0019 0.0001 0.0001
Onchocerca volvulus 0.0115 0.0308 0.0544
Trypanosoma brucei tubulin gamma chain 0.064 0.198 0.5412
Echinococcus granulosus NADP dependent isocitrate dehydrogenase 0.0032 0.004 0.0062
Trichomonas vaginalis ABC transporter, half transporter, putative 0.0033 0.0044 0.0109
Trichomonas vaginalis dihydrodiol dehydrogenase, putative 0.0253 0.0747 0.2034
Schistosoma mansoni hepatocyte nuclear factor 4-alpha (hnf-4-alpha) 0.0019 0.0001 0.0002
Onchocerca volvulus 0.0019 0.0001 0.0002
Mycobacterium tuberculosis Probable short-chain type dehydrogenase/reductase 0.006 0.0131 0.0241
Echinococcus multilocularis ATP binding cassette subfamily B (MDR:TAP) 0.0033 0.0044 0.0044
Trichomonas vaginalis conserved hypothetical protein 0.004 0.0067 0.0171
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0041 0.007 0.007
Mycobacterium leprae possible inositol monophosphatase SubH (IMPase) (inositol-1-phosphatase) (I-1-Pase ). 0.0036 0.0056 0.0079
Mycobacterium tuberculosis Probable polyketide synthase Pks15 0.0402 0.1222 0.2582
Schistosoma mansoni nuclear receptor nhr-48 0.0019 0.0001 0.0002
Mycobacterium tuberculosis Probable acyl carrier protein AcpA (ACP) 0.01 0.026 0.0518
Entamoeba histolytica zinc finger protein, putative 0.0091 0.023 0.0611
Schistosoma mansoni jumonji/arid domain-containing protein 0.016 0.0449 0.0685
Brugia malayi hypothetical protein 0.0019 0.0002 0.0003
Trichomonas vaginalis ATP-binding cassette transporter, putative 0.0033 0.0044 0.0109
Brugia malayi 6-phosphofructokinase 0.0107 0.0282 0.0474
Brugia malayi Tubulin alpha-2 chain 0.0902 0.2816 0.4732
Trichomonas vaginalis aldo-keto reductase, putative 0.0253 0.0747 0.2034
Onchocerca volvulus 0.0253 0.0747 0.132
Brugia malayi hypothetical protein 0.0027 0.0025 0.0042
Mycobacterium tuberculosis Probable polyketide synthase Pks7 0.1056 0.3308 0.7057
Mycobacterium tuberculosis Probable polyketide beta-ketoacyl synthase Pks4 0.0153 0.0426 0.0874
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0041 0.0069 0.0178
Mycobacterium ulcerans hypothetical protein 0.01 0.026 0.0518
Brugia malayi hypothetical protein 0.0027 0.0025 0.0042
Entamoeba histolytica pyrophosphate-dependent phosphofructokinase 0.0029 0.0032 0.0066
Echinococcus granulosus methyl CpG binding domain protein 2 0.0031 0.004 0.0062
Echinococcus granulosus poly (ADP ribose) polymerase 0.026 0.0769 0.1174
Chlamydia trachomatis fructose-6-phosphate phosphotransferase 0.0029 0.0032 0.0135
Loa Loa (eye worm) tubulin beta-1 chain 0.1165 0.3655 0.6934
Brugia malayi oxidoreductase, aldo/keto reductase family protein 0.0253 0.0747 0.1255
Trichomonas vaginalis conserved hypothetical protein 0.0027 0.0025 0.0057
Trichomonas vaginalis conserved hypothetical protein 0.0091 0.023 0.0619
Echinococcus multilocularis aldo keto reductase family 1, member B4 0.0253 0.0747 0.0747
Brugia malayi Tubulin gamma chain 0.064 0.198 0.3327
Mycobacterium leprae PROBABLE FATTY ACID SYNTHASE FAS (FATTY ACID SYNTHETASE) 0.0312 0.0936 0.1968
Mycobacterium tuberculosis S-nitrosomycothiol reductase MscR 0.0062 0.0137 0.0253
Plasmodium vivax cysteine repeat modular protein 1, putative 0.0022 0.001 0.0024
Onchocerca volvulus 0.0027 0.0026 0.0046
Echinococcus multilocularis jumonji domain containing 1A 0.004 0.0069 0.0069
Trichomonas vaginalis abcb9, putative 0.0033 0.0044 0.0109
Trypanosoma brucei DNA polymerase kappa, putative 0.0059 0.0128 0.0339
Echinococcus granulosus multidrug resistance protein 1 0.0033 0.0044 0.0067
Echinococcus multilocularis lysine specific demethylase 5A 0.0151 0.0423 0.0423
Echinococcus granulosus tubulin gamma 1 chain 0.064 0.198 0.3024
Toxoplasma gondii PHD-finger domain-containing protein 0.0027 0.0027 0.0054
Echinococcus granulosus nuclear receptor subfamily 4 group A 0.0019 0.0001 0.0002
Schistosoma mansoni hypothetical protein 0.0095 0.0243 0.0371
Echinococcus multilocularis multidrug resistance protein 1 0.0033 0.0044 0.0044
Schistosoma mansoni tubulin subunit beta 0.1165 0.3655 0.5582
Loa Loa (eye worm) phosphopantetheine attachment site family protein 0.01 0.026 0.0494
Trypanosoma cruzi PAB1-binding protein , putative 0.0025 0.0018 0.0029
Echinococcus multilocularis transcription factor btf3 0.0065 0.0146 0.0146
Trichomonas vaginalis lipid A export ATP-binding/permease protein msba, putative 0.0033 0.0044 0.0109
Loa Loa (eye worm) tubulin beta chain 0.1165 0.3655 0.6934
Giardia lamblia Epsilon tubulin 0.0278 0.0826 0.2244
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.0041 0.007 0.0133
Echinococcus granulosus multidrug resistance protein 1 0.0033 0.0044 0.0067
Trichomonas vaginalis aldo-keto reductase, putative 0.0073 0.0174 0.0464
Echinococcus multilocularis aldo keto reductase family 1, member B4 0.0253 0.0747 0.0747
Mycobacterium tuberculosis Probable isocitrate dehydrogenase [NADP] Icd1 (oxalosuccinate decarboxylase) (IDH) (NADP+-specific ICDH) (IDP) 0.0032 0.004 0.0046
Echinococcus multilocularis importin subunit beta 1 0.0056 0.0118 0.0118
Loa Loa (eye worm) tubulin beta-2A chain 0.1165 0.3655 0.6934
Mycobacterium ulcerans 3-oxoacyl-(acyl carrier protein) synthase II 0.025 0.0736 0.1538
Mycobacterium leprae Probable fatty-acid-CoA synthetase FadD22 (fatty-acid-CoA ligase) (fatty-acid-CoA synthase) 0.0108 0.0284 0.0567
Toxoplasma gondii alpha tubulin TUBA1 0.0902 0.2816 0.77
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.0041 0.007 0.0133
Brugia malayi topoisomerase 0.0027 0.0025 0.0042
Loa Loa (eye worm) hypothetical protein 0.0027 0.0025 0.0048
Echinococcus granulosus nuclear receptor subfamily 1 group D 0.0022 0.0009 0.0013
Onchocerca volvulus Tankyrase homolog 0.0091 0.023 0.0407
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.0118 0.0317 0.0483
Plasmodium vivax ataxin-2 like protein, putative 0.0025 0.0018 0.0045
Brugia malayi Beta-ketoacyl synthase, N-terminal domain containing protein 0.0995 0.3111 0.5228
Trichomonas vaginalis tubulin epsilon chain, putative 0.0902 0.2816 0.7702
Mycobacterium ulcerans cytochrome P450 185A4 Cyp185A4 0.0038 0.0061 0.0091
Schistosoma mansoni hypothetical protein 0.0019 0.0002 0.0002
Giardia lamblia ABC transporter 0.006 0.0132 0.034
Chlamydia trachomatis fructose-6-phosphate phosphotransferase 0.0029 0.0032 0.0135
Trichomonas vaginalis CMGC family protein kinase 0.1068 0.3347 0.9156
Leishmania major alpha tubulin 0.0902 0.2816 0.77
Brugia malayi ATP-dependent DNA helicase, RecQ family protein 0.0028 0.0029 0.0049
Schistosoma mansoni thyroid hormone receptor 0.0041 0.007 0.0107
Toxoplasma gondii histone lysine acetyltransferase GCN5-A 0.0043 0.0077 0.0191
Leishmania major d-xylulose reductase, putative 0.0062 0.0137 0.0355
Mycobacterium tuberculosis Conserved protein 0.03 0.0895 0.188
Brugia malayi latrophilin 2 splice variant baaae 0.0205 0.0595 0.1
Trypanosoma cruzi isocitrate dehydrogenase, putative 0.0032 0.004 0.009
Loa Loa (eye worm) tnks protein 0.0091 0.023 0.0437
Loa Loa (eye worm) BEN-1 protein 0.1165 0.3655 0.6934
Trypanosoma brucei DNA polymerase IV, putative 0.0059 0.0128 0.0339
Brugia malayi Heterochromatin protein 1 0.0071 0.0166 0.0279
Mycobacterium tuberculosis Probable 6-phosphofructokinase PfkA (phosphohexokinase) (phosphofructokinase) 0.0106 0.0279 0.0558
Loa Loa (eye worm) hypothetical protein 0.0027 0.0027 0.0052
Loa Loa (eye worm) hypothetical protein 0.0553 0.1704 0.3232
Brugia malayi Pre-SET motif family protein 0.0035 0.005 0.0084
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.003 0.0036 0.0087
Loa Loa (eye worm) alpha-tubulin isotype 2 0.0624 0.193 0.3662
Entamoeba histolytica NADP-dependent alcohol dehydrogenase, putative 0.0062 0.0137 0.0355
Plasmodium vivax 3-oxoacyl-[acyl-carrier-protein] synthase i/ii, putative 0.025 0.0736 0.201
Onchocerca volvulus 0.0073 0.0174 0.0307
Mycobacterium tuberculosis Probable polyketide synthase Pks5 0.0964 0.3014 0.6426
Trichomonas vaginalis phosphofructokinase, putative 0.0106 0.0279 0.0752
Schistosoma mansoni ap endonuclease 0.0039 0.0064 0.0098
Mycobacterium leprae PHENOLPTHIOCEROL SYNTHESIS TYPE-I POLYKETIDE SYNTHASE PPSA 0.0995 0.3111 0.6635
Leishmania major beta tubulin 0.1165 0.3655 1
Brugia malayi Bromodomain containing protein 0.0146 0.0407 0.0683
Echinococcus multilocularis muscleblind protein 0.0305 0.0912 0.0912
Echinococcus multilocularis aldo keto reductase 0.0253 0.0747 0.0747
Mycobacterium ulcerans oxidoreductase 0.0253 0.0747 0.1561
Brugia malayi conserved hypotetical protein 0.0019 0.0001 0.0002
Echinococcus multilocularis 6 phosphofructokinase 0.0106 0.0279 0.0279
Mycobacterium tuberculosis Probable fatty acid synthase Fas (fatty acid synthetase) 0.0312 0.0936 0.1968
Plasmodium falciparum tubulin beta chain 0.1165 0.3655 1
Trypanosoma brucei epsilon tubulin 0.064 0.198 0.5412
Trichomonas vaginalis aldo-keto reductase, putative 0.0253 0.0747 0.2034
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.003 0.0036 0.0087
Echinococcus granulosus inositol monophosphatase 1 0.0041 0.0069 0.0106
Echinococcus granulosus importin subunit beta 1 0.0056 0.0118 0.018
Brugia malayi nuclear receptor NHR-67 0.0019 0.0001 0.0002
Mycobacterium ulcerans oxidoreductase 0.0062 0.0137 0.0253
Mycobacterium tuberculosis Possible dehydrogenase 0.0062 0.0137 0.0253
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0022 0.0009 0.0013
Trichomonas vaginalis conserved hypothetical protein 0.0065 0.0146 0.0388
Trichomonas vaginalis tubulin epsilon chain, putative 0.0902 0.2816 0.7702
Trichomonas vaginalis chromobox protein, putative 0.0043 0.0076 0.0197
Echinococcus granulosus histone acetyltransferase KAT2B 0.0043 0.0077 0.0118
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.0041 0.007 0.0107
Mycobacterium ulcerans polyketide synthase 0.1056 0.3308 0.7057
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0041 0.007 0.0107
Brugia malayi CHD4 protein 0.002 0.0003 0.0005
Echinococcus granulosus geminin 0.0504 0.1546 0.2361
Mycobacterium tuberculosis Probable thioesterase TesA 0.0829 0.2583 0.55
Loa Loa (eye worm) hypothetical protein 0.1672 0.5271 1
Trichomonas vaginalis tubulin gamma chain, putative 0.064 0.198 0.5413
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.0041 0.007 0.007
Leishmania major beta tubulin 0.1165 0.3655 1
Schistosoma mansoni DNA helicase recq1 0.0028 0.0029 0.0045
Echinococcus multilocularis Tubulin beta 2C chain 0.1165 0.3655 0.3655
Plasmodium falciparum tubulin epsilon chain, putative 0.064 0.198 0.5416
Brugia malayi hypothetical protein 0.0022 0.0009 0.0014
Loa Loa (eye worm) hypothetical protein 0.0027 0.0025 0.0048
Echinococcus granulosus alpha tubulin 0.0902 0.2816 0.4301
Echinococcus multilocularis tubulin subunit beta 0.1165 0.3655 0.3655
Schistosoma mansoni hypothetical protein 0.01 0.026 0.0398
Trichomonas vaginalis aldo-keto reductase, putative 0.0253 0.0747 0.2034
Mycobacterium tuberculosis Probable zinc-type alcohol dehydrogenase AdhD (aldehyde reductase) 0.0062 0.0137 0.0253
Brugia malayi Tubulin alpha chain 0.0278 0.0826 0.1388
Schistosoma mansoni nuclear receptor 0.0019 0.0001 0.0002
Brugia malayi F/Y-rich N-terminus family protein 0.0039 0.0063 0.0106
Leishmania major isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0032 0.004 0.009
Schistosoma mansoni smad1 5 8 and 0.0024 0.0017 0.0027
Schistosoma mansoni glutaminase 0.0273 0.081 0.1237
Trichomonas vaginalis set domain proteins, putative 0.0262 0.0775 0.2112
Mycobacterium leprae PROBABLE NADP-DEPENDENT ALCOHOL DEHYDROGENASE ADHC 0.0062 0.0137 0.0253
Schistosoma mansoni jumonji domain containing protein 0.019 0.0544 0.0831
Toxoplasma gondii type I fatty acid synthase 0.0153 0.0426 0.1149
Loa Loa (eye worm) nuclear receptor NHR-67 0.0019 0.0001 0.0002
Leishmania major beta tubulin 0.1165 0.3655 1
Mycobacterium tuberculosis Polyketide synthase Pks12 0.1056 0.3308 0.7057
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.0041 0.007 0.0133
Plasmodium falciparum replication factor C subunit 1, putative 0.0027 0.0025 0.0065
Echinococcus granulosus aldo keto reductase family 1 member B4 0.0253 0.0747 0.114
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.003 0.0036 0.0087
Schistosoma mansoni transcription factor btf3 0.0065 0.0146 0.0223
Loa Loa (eye worm) hypothetical protein 0.0296 0.0882 0.1674
Echinococcus multilocularis tyrosyl DNA phosphodiesterase 1 0.007 0.0164 0.0164
Mycobacterium ulcerans phenyloxazoline synthase MbtB 0.0108 0.0284 0.0567
Loa Loa (eye worm) transcription factor SMAD2 0.0356 0.1076 0.2041
Echinococcus granulosus ATP binding cassette subfamily B MDR:TAP 0.0033 0.0044 0.0067
Schistosoma mansoni cellular tumor antigen P53 0.005 0.0098 0.015
Onchocerca volvulus 0.0362 0.1094 0.1935
Echinococcus multilocularis tubulin alpha 1C chain 0.0902 0.2816 0.2816
Trypanosoma cruzi JmjC domain, hydroxylase, putative 0.004 0.0069 0.0168
Trypanosoma cruzi aldo/keto reductase, putative 0.0073 0.0174 0.0456
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.0041 0.007 0.0133
Trypanosoma cruzi Acyl carrier protein, mitochondrial, putative 0.01 0.026 0.0693
Trichomonas vaginalis DNA helicase recq, putative 0.004 0.0068 0.0175
Entamoeba histolytica P-glycoprotein-2, putative 0.0033 0.0044 0.01
Brugia malayi DKFZp564C0469 protein 0.0027 0.0025 0.0042
Trichomonas vaginalis replication factor C large subunit, putative 0.0027 0.0025 0.0057
Schistosoma mansoni tubulin subunit alpha 0.0902 0.2816 0.4301
Entamoeba histolytica NADP-dependent alcohol dehydrogenase 0.0062 0.0137 0.0355
Mycobacterium ulcerans polyketide synthase Pks9 0.0658 0.2037 0.433
Giardia lamblia Beta tubulin 0.1165 0.3655 1
Echinococcus granulosus zinc finger protein 0.0044 0.008 0.0123
Brugia malayi ABC transporter family protein 0.0033 0.0044 0.0074
Echinococcus granulosus chromodomain helicase DNA binding protein 4 0.002 0.0003 0.0005
Schistosoma mansoni hypothetical protein 0.0504 0.1546 0.2361
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0019 0.0001 0.0002
Leishmania major 4-coumarate:coa ligase-like protein 0.0025 0.0019 0.0032
Echinococcus granulosus ATP binding cassette sub family G 0.0061 0.0135 0.0206
Trypanosoma cruzi hypothetical protein, conserved 0.0022 0.001 0.0008
Loa Loa (eye worm) BEN-1 protein 0.1165 0.3655 0.6934
Echinococcus multilocularis JmjC domain containing protein 4 0.004 0.0069 0.0069
Brugia malayi Kringle domain containing protein 0.0022 0.001 0.0018
Mycobacterium tuberculosis Cell division protein FtsZ 0.0278 0.0826 0.1731
Echinococcus granulosus ATP binding cassette subfamily B MDR:TAP 0.0033 0.0044 0.0067
Leishmania major hypothetical protein, conserved 0.0058 0.0126 0.0324
Loa Loa (eye worm) hypothetical protein 0.0019 0.0001 0.0002
Schistosoma mansoni NADP-specific isocitrate dehydrogenase 0.0032 0.004 0.0062
Brugia malayi GTP-binding nuclear protein RAN/TC4 0.0021 0.0008 0.0013
Brugia malayi oxidoreductase, aldo/keto reductase family protein 0.0253 0.0747 0.1255
Schistosoma mansoni hypothetical protein 0.0028 0.003 0.0046
Trichomonas vaginalis multidrug resistance protein 1, 2, putative 0.0033 0.0044 0.0109
Loa Loa (eye worm) hypothetical protein 0.054 0.1662 0.3152
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0019 0.0001 0.0001
Loa Loa (eye worm) alcohol dehydrogenase class III 0.0062 0.0137 0.026
Trichomonas vaginalis conserved hypothetical protein 0.0278 0.0826 0.225
Trichomonas vaginalis tubulin beta chain, putative 0.0902 0.2816 0.7702
Echinococcus multilocularis tubulin delta chain 0.0278 0.0826 0.0826
Leishmania major ATP-binding cassette protein subfamily B, member 2, putative 0.0033 0.0044 0.01
Schistosoma mansoni ecdysone-induced protein 78c (dr-78) 0.0022 0.0009 0.0013
Echinococcus multilocularis poly (ADP ribose) polymerase 1 0.0754 0.2345 0.2345
Toxoplasma gondii phosphofructokinase domain-containing protein 0.0029 0.0032 0.0066
Trichomonas vaginalis aldo/keto reductase, putative 0.0253 0.0747 0.2034
Echinococcus multilocularis tubulin gamma 1 chain 0.064 0.198 0.198
Mycobacterium ulcerans transmembrane ABC transporter ATP-binding protein 0.0061 0.0135 0.0249
Trichomonas vaginalis conserved hypothetical protein 0.0091 0.023 0.0619
Echinococcus granulosus tubulin subunit beta 0.1165 0.3655 0.5582
Echinococcus granulosus tubulin alpha chain 0.0902 0.2816 0.4301
Plasmodium falciparum acyl carrier protein 0.01 0.026 0.0708
Trichomonas vaginalis phosphofructokinase, putative 0.0029 0.0032 0.0074
Trypanosoma cruzi apurinic/apyrimidinic endonuclease 0.0039 0.0064 0.0156
Brugia malayi ImpB/MucB/SamB family protein 0.0058 0.0125 0.021
Plasmodium falciparum ataxin-2 like protein, putative 0.0025 0.0018 0.0045
Schistosoma mansoni bromodomain-containing nuclear protein 1 brd1 0.0027 0.0027 0.0042
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0055 0.0116 0.0177
Mycobacterium tuberculosis Conserved hypothetical protein 0.01 0.026 0.0518
Entamoeba histolytica hypothetical protein 0.0091 0.023 0.0611
Trypanosoma brucei inositol-1(or 4)-monophosphatase 1, putative 0.0041 0.0069 0.0178
Trypanosoma cruzi oxidoreductase, putative 0.0062 0.0137 0.0355
Toxoplasma gondii aldo/keto reductase family oxidoreductase 0.0073 0.0174 0.0456
Trichomonas vaginalis multidrug resistance protein 1, 2, putative 0.0033 0.0044 0.0109
Trichomonas vaginalis lipid A export ATP-binding/permease protein msba, putative 0.0033 0.0044 0.0109
Trichomonas vaginalis conserved hypothetical protein 0.0028 0.003 0.007
Echinococcus granulosus jumonji domain containing 1A 0.004 0.0069 0.0105
Leishmania major DNA polymerase kappa, putative,DNA polymerase IV, putative 0.0039 0.0066 0.016
Leishmania major gamma-tubulin 0.064 0.198 0.5409
Trichomonas vaginalis conserved hypothetical protein 0.0065 0.0146 0.0388
Loa Loa (eye worm) heterochromatin protein 1 0.0071 0.0166 0.0315
Loa Loa (eye worm) hypothetical protein 0.0019 0.0001 0.0002
Trichomonas vaginalis conserved hypothetical protein 0.0028 0.003 0.007
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0066 0.0151 0.023
Loa Loa (eye worm) hypothetical protein 0.0027 0.0026 0.005
Echinococcus granulosus ATP dependent DNA helicase Q1 0.0028 0.0029 0.0045
Trypanosoma cruzi NADP-dependent alcohol hydrogenase, putative 0.0062 0.0137 0.0355
Schistosoma mansoni DNA ligase IV 0.0027 0.0025 0.0038
Trypanosoma brucei hypothetical protein, conserved 0.0026 0.0022 0.0048
Echinococcus multilocularis ATP binding cassette subfamily B (MDR:TAP) 0.0033 0.0044 0.0044
Trypanosoma brucei alpha tubulin 0.0902 0.2816 0.7702
Trichomonas vaginalis phosphofructokinase, putative 0.0029 0.0032 0.0074
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.0041 0.007 0.0107
Brugia malayi ImpB/MucB/SamB family protein 0.0033 0.0045 0.0076
Trypanosoma brucei DNA polymerase IV, putative 0.0053 0.0108 0.0283
Entamoeba histolytica tyrosyl-DNA phosphodiesterase, putative 0.007 0.0164 0.0428
Onchocerca volvulus 0.0296 0.0882 0.156
Schistosoma mansoni DNA helicase recq5 0.0028 0.0029 0.0045
Leishmania major p-glycoprotein 0.0033 0.0044 0.01
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0051 0.0101 0.0257
Leishmania major alpha tubulin 0.0902 0.2816 0.77
Loa Loa (eye worm) poly(ADP-ribose) polymerase 0.0362 0.1096 0.2079
Trypanosoma cruzi transcription factor btf3, putative 0.0065 0.0146 0.0379
Onchocerca volvulus 0.0027 0.0025 0.0045
Trypanosoma brucei beta tubulin 0.064 0.198 0.5412
Leishmania major ferric reductase, putative 0.0034 0.0049 0.0114
Trichomonas vaginalis aldo-keto reductase, putative 0.0253 0.0747 0.2034
Brugia malayi ecdysone receptor 0.0019 0.0001 0.0002
Trichomonas vaginalis abcb9, putative 0.0033 0.0044 0.0109
Trypanosoma cruzi acyl transferase-like protein, putative 0.0063 0.014 0.0364
Trichomonas vaginalis phosphofructokinase, putative 0.0106 0.0279 0.0752
Trypanosoma cruzi beta-ketoacyl synthase family protein, putative 0.025 0.0736 0.1997
Schistosoma mansoni rab6-interacting 0.0019 0.0002 0.0002
Mycobacterium tuberculosis Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) 0.0039 0.0064 0.0098
Trypanosoma cruzi tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.007 0.0164 0.0428
Schistosoma mansoni tankyrase 0.0091 0.023 0.0352
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.003 0.0036 0.0087
Trypanosoma brucei beta tubulin 0.1165 0.3655 1
Entamoeba histolytica acyl-CoA synthetase, putative 0.0125 0.0339 0.091
Loa Loa (eye worm) hypothetical protein 0.0041 0.007 0.0133
Loa Loa (eye worm) hypothetical protein 0.0022 0.0009 0.0016
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.1068 0.3347 0.9155
Plasmodium falciparum holo-[acyl-carrier-protein] synthase, putative 0.0026 0.0022 0.0056
Echinococcus multilocularis aldehyde dehydrogenase, mitochondrial 0.0131 0.0358 0.0358
Loa Loa (eye worm) beta-ketoacyl synthase domain-containing protein 0.025 0.0736 0.1396
Trypanosoma brucei protein kinase, putative 0.1068 0.3347 0.9156
Entamoeba histolytica P-glyco protein 6, putative 0.0033 0.0044 0.01
Entamoeba histolytica hypothetical protein 0.0073 0.0174 0.0457
Plasmodium falciparum ATP-dependent 6-phosphofructokinase 0.0029 0.0032 0.0082
Trypanosoma cruzi cytochrome P450, putative 0.0038 0.0061 0.0148
Leishmania major hypothetical protein, conserved 0.0025 0.0018 0.0029
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.006 0.0131 0.0241
Echinococcus multilocularis FTZ F1 alpha 0.0041 0.007 0.007
Plasmodium vivax tubulin beta chain, putative 0.1165 0.3655 1
Echinococcus multilocularis tubulin epsilon chain 0.064 0.198 0.198
Mycobacterium ulcerans NADP-dependent alcohol dehydrogenase Adh 0.0062 0.0137 0.0253
Brugia malayi Smad1 0.0024 0.0017 0.0029
Trichomonas vaginalis phosphofructokinase, putative 0.0106 0.0279 0.0752
Mycobacterium tuberculosis Phenolpthiocerol synthesis type-I polyketide synthase PpsB 0.0153 0.0426 0.0874
Giardia lamblia Aldose reductase 0.0253 0.0747 0.2027
Toxoplasma gondii ABC transporter transmembrane region domain-containing protein 0.0033 0.0044 0.01
Loa Loa (eye worm) 3-hydroxyacyl-CoA dehydrogenase type II 0.0052 0.0107 0.0203
Trichomonas vaginalis tubulin epsilon chain, putative 0.1165 0.3655 1
Echinococcus multilocularis aldo keto reductase family 1, member B4 0.0253 0.0747 0.0747
Echinococcus granulosus tubulin alpha 3 chain 0.0902 0.2816 0.4301
Loa Loa (eye worm) hypothetical protein 0.0058 0.0126 0.0239
Echinococcus multilocularis zinc finger protein 0.0044 0.008 0.008
Schistosoma mansoni methyl-cpg binding protein mbd 0.0031 0.004 0.0062
Mycobacterium ulcerans Type I modular polyketide synthase 0.0995 0.3111 0.6635
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0041 0.007 0.0107
Brugia malayi phosphofructokinase 0.0106 0.0279 0.0469
Mycobacterium ulcerans aldehyde dehydrogenase 0.0131 0.0358 0.0728
Onchocerca volvulus 0.0027 0.0026 0.0046
Echinococcus granulosus 3 hydroxyacyl coenzyme A dehydrogenase type 2 0.006 0.0131 0.02
Schistosoma mansoni zinc finger protein 0.0019 0.0001 0.0002
Giardia lamblia PHD finger protein 15 0.0027 0.0027 0.0054
Echinococcus granulosus ecdysone induced protein 78C 0.0041 0.007 0.0107
Schistosoma mansoni gabp alpha 0.0068 0.0157 0.024
Loa Loa (eye worm) hypothetical protein 0.0557 0.1717 0.3257
Echinococcus granulosus tubulin beta 4A class IVa 0.1165 0.3655 0.5582
Loa Loa (eye worm) hypothetical protein 0.0036 0.0056 0.0105
Brugia malayi oxidoreductase, aldo/keto reductase family protein 0.0253 0.0747 0.1255
Plasmodium vivax JmjC domain containing protein 0.004 0.0069 0.0184
Loa Loa (eye worm) Smad1 0.0024 0.0017 0.0033
Treponema pallidum diphosphate--fructose-6-phosphate 1-phosphotransferase 0.0106 0.0279 0.3197
Trypanosoma cruzi beta-ketoacyl synthase family protein, putative 0.025 0.0736 0.1997
Trypanosoma cruzi Poly(ADP-ribose) polymerase and DNA-Ligase Zn-finger region/Zinc-finger (CX5CX6HX5H) motif containing protein, putative 0.0058 0.0126 0.0324
Schistosoma mansoni ap endonuclease 0.0039 0.0064 0.0098
Mycobacterium ulcerans glutaminase 0.0273 0.081 0.1697
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0073 0.0174 0.0266
Loa Loa (eye worm) hypothetical protein 0.0027 0.0025 0.0047
Echinococcus multilocularis aldo keto reductase 0.0253 0.0747 0.0747
Echinococcus granulosus aldo keto reductase family 1 member B4 0.0253 0.0747 0.114
Echinococcus multilocularis poly (adp ribose) polymerase 2 0.0553 0.1704 0.1704
Mycobacterium tuberculosis Probable transmembrane multidrug efflux pump 0.0033 0.0044 0.0054
Echinococcus granulosus aldo keto reductase 0.0253 0.0747 0.114
Echinococcus granulosus tubulin beta 1 chain 0.1165 0.3655 0.5582
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.003 0.0036 0.0087
Trichomonas vaginalis ran, putative 0.0021 0.0008 0.0009
Brugia malayi hypothetical protein 0.012 0.0322 0.0541
Trichomonas vaginalis RNA polymerase II ctd phosphatase, putative 0.0027 0.0025 0.0057
Leishmania major hypothetical protein, conserved 0.03 0.0895 0.2434
Echinococcus granulosus ATP binding cassette subfamily B MDR:TAP 0.0033 0.0044 0.0067
Loa Loa (eye worm) hypothetical protein 0.0041 0.007 0.0133
Leishmania major 4-coumarate:coa ligase-like protein 0.0025 0.0019 0.0032
Trypanosoma cruzi tubulin gamma chain 0.064 0.198 0.5409
Trichomonas vaginalis tubulin beta chain, putative 0.0902 0.2816 0.7702
Plasmodium falciparum multidrug resistance protein 1 0.0033 0.0044 0.0116
Loa Loa (eye worm) hypothetical protein 0.0041 0.007 0.0133
Echinococcus granulosus Tubulin beta 2C chain 0.1165 0.3655 0.5582
Echinococcus granulosus tubulin alpha chain 0.0902 0.2816 0.4301
Schistosoma mansoni nuclear hormone receptor superfamily protein-related 0.0019 0.0001 0.0002
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0035 0.005 0.005
Trypanosoma brucei beta-ketoacyl-ACP synthase 0.025 0.0736 0.2004
Mycobacterium ulcerans phenolpthiocerol synthesis type-I polyketide synthase PpsB 0.08 0.2492 0.5305
Trypanosoma brucei Acyl carrier protein, mitochondrial 0.01 0.026 0.0701
Plasmodium vivax acyl carrier protein, putative 0.01 0.026 0.0708
Echinococcus multilocularis aldo keto reductase family 1, member B4 0.0253 0.0747 0.0747
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0066 0.0151 0.0151
Onchocerca volvulus 0.0019 0.0001 0.0002
Schistosoma mansoni aldo-keto reductase 0.0253 0.0747 0.114
Echinococcus multilocularis tubulin alpha 0.064 0.198 0.198
Trichomonas vaginalis phosphofructokinase, putative 0.0029 0.0032 0.0074
Mycobacterium leprae Polyketide synthase Pks13 0.1487 0.468 1
Brugia malayi Blistered cuticle protein 3 0.0034 0.0049 0.0082
Mycobacterium ulcerans fatty acid synthase Fas 0.0312 0.0936 0.1968
Onchocerca volvulus Heterochromatin protein 1 homolog 0.0043 0.0076 0.0135
Plasmodium vivax ADP-dependent DNA helicase RecQ, putative 0.0024 0.0016 0.0041
Trichomonas vaginalis aldo-keto reductase, putative 0.0253 0.0747 0.2034
Loa Loa (eye worm) hypothetical protein 0.03 0.0898 0.1704
Echinococcus granulosus transcription factor btf3 0.0065 0.0146 0.0223
Trichomonas vaginalis tubulin, putative 0.1165 0.3655 1
Loa Loa (eye worm) pigment dispersing factor receptor c 0.03 0.0898 0.1704
Schistosoma mansoni multidrug resistance protein 0.0033 0.0044 0.0067
Trypanosoma cruzi ABC transporter, putative 0.0061 0.0135 0.035
Mycobacterium leprae Probable fatty-acid-CoA ligase FadD9 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0101 0.0264 0.0525
Brugia malayi MH2 domain containing protein 0.0024 0.0017 0.0029
Entamoeba histolytica hypothetical protein 0.0027 0.0025 0.0048
Mycobacterium leprae Probable S-nitrosomycothiol reductase MscR 0.0062 0.0137 0.0253
Trichomonas vaginalis tubulin beta chain, putative 0.0362 0.1094 0.2986
Echinococcus granulosus tubulin alpha 0.064 0.198 0.3024
Trypanosoma cruzi ferric reductase transmembrane protein, putative 0.0034 0.0049 0.0114
Echinococcus multilocularis mitogen activated protein kinase 0.1068 0.3347 0.3347
Leishmania major acyl carrier protein, putative 0.01 0.026 0.0693
Leishmania major beta tubulin 0.1165 0.3655 1
Brugia malayi ATP dependent DNA ligase C terminal region family protein 0.0027 0.0025 0.0042
Mycobacterium leprae conserved hypothetical protein 0.0026 0.0022 0.0006
Chlamydia trachomatis acyl carrier protein 0.01 0.026 0.3339
Trichomonas vaginalis lipid A export ATP-binding/permease protein msba, putative 0.0033 0.0044 0.0109
Leishmania major beta tubulin 0.1165 0.3655 1
Trypanosoma brucei GTP-binding nuclear protein rtb2, putative 0.0021 0.0008 0.0008
Trichomonas vaginalis ap endonuclease, putative 0.0039 0.0064 0.0165
Mycobacterium leprae Probable alcohol dehydrogenase AdhA 0.0062 0.0137 0.0253
Trypanosoma cruzi DNA polymerase eta, putative 0.0058 0.0125 0.0321
Schistosoma mansoni phd/f-box containing protein 0.004 0.0069 0.0105
Schistosoma mansoni jumonji domain containing protein 0.004 0.0069 0.0105
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.0041 0.007 0.0107
Schistosoma mansoni lamin 0.0027 0.0026 0.004
Brugia malayi jmjC domain containing protein 0.004 0.0069 0.0115
Loa Loa (eye worm) tubulin alpha-3 chain 0.054 0.1662 0.3152
Brugia malayi AMP-binding enzyme family protein 0.0025 0.0019 0.0032
Loa Loa (eye worm) hypothetical protein 0.0041 0.007 0.0133
Echinococcus granulosus Tubulin alpha 1 chain 0.0902 0.2816 0.4301
Plasmodium vivax tubulin epsilon chain, putative 0.064 0.198 0.5416
Schistosoma mansoni hypothetical protein 0.0107 0.028 0.0428
Echinococcus granulosus Tubulin alpha 1 chain 0.0902 0.2816 0.4301
Loa Loa (eye worm) oxidoreductase 0.0253 0.0747 0.1417
Trichomonas vaginalis multidrug resistance protein 1, 2, putative 0.0033 0.0044 0.0109
Leishmania major hypothetical protein, conserved 0.0063 0.014 0.0364
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0032 0.004 0.004
Trichomonas vaginalis aldo/keto reductase, putative 0.0253 0.0747 0.2034
Schistosoma mansoni hypothetical protein 0.0504 0.1546 0.2361
Loa Loa (eye worm) CXXC zinc finger family protein 0.0082 0.02 0.038
Leishmania major NADP-dependent alcohol dehydrogenase, putative 0.0062 0.0137 0.0355
Brugia malayi nuclear receptor subfamily 1, group D, member 1, putative 0.0019 0.0001 0.0002
Mycobacterium tuberculosis Probable NADPH quinone oxidoreductase FadB4 (NADPH:quinone reductase) (zeta-crystallin) 0.0062 0.0137 0.0253
Leishmania major zinc binding dehydrogenase-like protein 0.0062 0.0137 0.0355
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0041 0.007 0.0107
Onchocerca volvulus 0.0253 0.0747 0.132
Mycobacterium tuberculosis Polyketide synthase Pks2 0.0964 0.3014 0.6426
Loa Loa (eye worm) jmjC domain-containing protein 0.004 0.0069 0.013
Echinococcus granulosus poly (ADP ribose) polymerase 0.0191 0.0548 0.0837
Treponema pallidum acyl carrier protein 0.01 0.026 0.2966
Echinococcus multilocularis Polycystic kidney disease protein 0.0019 0.0002 0.0002
Trypanosoma brucei beta tubulin 0.1165 0.3655 1
Mycobacterium ulcerans Type I modular polyketide synthase 0.0995 0.3111 0.6635
Echinococcus granulosus tubulin alpha chain 0.0902 0.2816 0.4301
Leishmania major aldehyde reductase, putative,oxidoreductase, putative 0.0253 0.0747 0.2027
Loa Loa (eye worm) tubulin alpha chain 0.0902 0.2816 0.5342
Loa Loa (eye worm) hypothetical protein 0.0078 0.019 0.0361
Brugia malayi Importin beta-1 subunit 0.0056 0.0118 0.0199
Trichomonas vaginalis aldo-keto reductase, putative 0.0073 0.0174 0.0464
Mycobacterium tuberculosis Peptide synthetase MbtE (peptide synthase) 0.0108 0.0284 0.0567
Echinococcus multilocularis lamin 0.0027 0.0026 0.0026
Mycobacterium ulcerans zinc-dependent alcohol dehydrogenase 0.0062 0.0137 0.0253
Trypanosoma brucei beta tubulin 0.1165 0.3655 1
Echinococcus granulosus tankyrase 0.0091 0.023 0.0352
Brugia malayi Nuclear hormone receptor family member nhr-14 0.0041 0.007 0.0117
Echinococcus granulosus aldehyde dehydrogenase mitochondrial 0.0131 0.0358 0.0547
Trypanosoma brucei transcription factor BTF3, putative 0.0065 0.0146 0.0387
Loa Loa (eye worm) AMP-binding enzyme family protein 0.0937 0.2926 0.5552
Schistosoma mansoni poly [ADP-ribose] polymerase 0.0553 0.1704 0.2602
Loa Loa (eye worm) cytochrome P450 family protein 0.0038 0.0061 0.0117
Mycobacterium ulcerans NAD-dependent DNA ligase LigA 0.0027 0.0025 0.0013
Mycobacterium ulcerans Type I modular polyketide synthase 0.0995 0.3111 0.6635
Schistosoma mansoni zinc finger protein 0.0044 0.008 0.0123
Brugia malayi isocitrate dehydrogenase 0.0032 0.004 0.0068
Loa Loa (eye worm) hypothetical protein 0.0624 0.193 0.3662
Onchocerca volvulus Fatty acid synthase homolog 0.1793 0.5657 1
Brugia malayi steroid hormone receptor 0.0041 0.007 0.0117
Brugia malayi Tyrosyl-DNA phosphodiesterase family protein 0.007 0.0164 0.0275
Brugia malayi Nuclear hormone receptor family member nhr-41 0.0041 0.007 0.0117
Loa Loa (eye worm) hypothetical protein 0.012 0.0322 0.0611
Trichomonas vaginalis conserved hypothetical protein 0.0027 0.0025 0.0057
Echinococcus multilocularis tubulin alpha 3 chain 0.0902 0.2816 0.2816
Trichomonas vaginalis ATP-binding cassette transporter, putative 0.0033 0.0044 0.0109
Trichomonas vaginalis aldo-keto reductase, putative 0.0253 0.0747 0.2034
Echinococcus granulosus JmjC domain containing protein 4 0.004 0.0069 0.0105
Toxoplasma gondii kringle domain-containing protein 0.0022 0.001 0.0008
Loa Loa (eye worm) hypothetical protein 0.0019 0.0001 0.0002
Schistosoma mansoni loxhd1 0.0019 0.0002 0.0002
Trypanosoma cruzi nuclear receptor binding factor, putative 0.0062 0.0137 0.0355
Trichomonas vaginalis tubulin beta chain, putative 0.0902 0.2816 0.7702
Echinococcus granulosus tubulin epsilon chain 0.064 0.198 0.3024
Onchocerca volvulus 0.0033 0.0044 0.0078
Mycobacterium tuberculosis Probable aldehyde dehydrogenase 0.0131 0.0358 0.0728
Onchocerca volvulus Huntingtin homolog 0.012 0.0322 0.0569
Trypanosoma cruzi nuclear receptor binding factor, putative 0.0062 0.0137 0.0355
Echinococcus multilocularis Tubulin alpha 1 chain 0.0902 0.2816 0.2816
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.0066 0.0152 0.0152
Schistosoma mansoni tubulin subunit delta 0.0278 0.0826 0.1261
Onchocerca volvulus 0.0091 0.0231 0.0409
Plasmodium falciparum isocitrate dehydrogenase [NADP], mitochondrial 0.0032 0.004 0.0106
Mycobacterium ulcerans polyketide synthase MbtD 0.0306 0.0915 0.1922
Loa Loa (eye worm) hypothetical protein 0.0087 0.0216 0.041
Brugia malayi hypothetical protein 0.0296 0.0882 0.1483
Brugia malayi Nuclear hormone receptor E75 0.0019 0.0001 0.0002
Loa Loa (eye worm) hypothetical protein 0.0041 0.007 0.0133
Giardia lamblia Gamma tubulin 0.064 0.198 0.5409
Schistosoma mansoni gcn5proteinral control of amino-acid synthesis 5-like 2 gcnl2 0.0136 0.0373 0.0569
Loa Loa (eye worm) alpha-tubulin 0.0902 0.2816 0.5342
Plasmodium falciparum ADP-dependent DNA helicase RecQ 0.0038 0.006 0.0161
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0055 0.0116 0.0116
Trichomonas vaginalis conserved hypothetical protein 0.0091 0.023 0.0619
Trypanosoma brucei isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0032 0.004 0.0098
Echinococcus granulosus aldo keto reductase family 1 member B4 0.0253 0.0747 0.114
Echinococcus multilocularis aldo keto reductase family 1, member B4 0.0253 0.0747 0.0747
Toxoplasma gondii ImpB/MucB/SamB family protein 0.0035 0.0052 0.0122
Loa Loa (eye worm) intermediate filament protein 0.0027 0.0026 0.005
Toxoplasma gondii LsmAD domain-containing protein 0.0025 0.0018 0.0029
Echinococcus multilocularis tubulin beta 1 chain 0.1165 0.3655 0.3655
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0095 0.0243 0.0243
Echinococcus granulosus aldo keto reductase family 1 member B4 0.0253 0.0747 0.114
Echinococcus granulosus mothers against decapentaplegic 5 0.0024 0.0017 0.0027
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0035 0.005 0.0077
Loa Loa (eye worm) ATP-binding cassette sub-family B member 2 0.0033 0.0044 0.0083
Giardia lamblia DINP protein human, muc B family 0.0039 0.0066 0.016
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0095 0.0243 0.0243
Loa Loa (eye worm) hypothetical protein 0.0019 0.0001 0.0002
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0019 0.0001 0.0002
Trichomonas vaginalis CMGC family protein kinase 0.1068 0.3347 0.9156
Loa Loa (eye worm) hypothetical protein 0.0095 0.0243 0.0461
Brugia malayi glutamate-cysteine ligase modifier subunit 0.0073 0.0174 0.0292
Mycobacterium tuberculosis Probable multifunctional mycocerosic acid synthase membrane-associated Mas 0.1056 0.3308 0.7057
Plasmodium vivax 6-phosphofructokinase, putative 0.0029 0.0032 0.0082
Onchocerca volvulus Alhambra homolog 0.0027 0.0027 0.0048
Loa Loa (eye worm) bromodomain containing protein 0.0036 0.0054 0.0103
Leishmania major aldehyde dehydrogenase, mitochondrial precursor 0.0131 0.0358 0.0962
Brugia malayi nuclear hormone receptor family member odr-7 0.0019 0.0001 0.0002
Echinococcus granulosus tumor protein p63 0.0339 0.1021 0.1559
Brugia malayi exodeoxyribonuclease III family protein 0.0039 0.0064 0.0108
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0022 0.0009 0.0012
Trichomonas vaginalis tubulin alpha-1 chain, putative 0.0902 0.2816 0.7702
Trypanosoma cruzi oxidoreductase, putative 0.0062 0.0137 0.0355
Plasmodium falciparum aldo-keto reductase, putative 0.0073 0.0174 0.0471
Echinococcus granulosus Tubulin beta 2C chain 0.1165 0.3655 0.5582
Brugia malayi Cell division protein ftsZ 0.0278 0.0826 0.1388
Trichomonas vaginalis conserved hypothetical protein 0.0091 0.023 0.0619
Loa Loa (eye worm) tubulin alpha 2 0.0262 0.0776 0.1472
Schistosoma mansoni microtubule-associated protein tau 0.2072 0.6548 1
Trichomonas vaginalis lipid A export ATP-binding/permease protein msba, putative 0.0033 0.0044 0.0109
Wolbachia endosymbiont of Brugia malayi fructose-1,6-bisphosphatase 0.0041 0.0069 0.0591
Trichomonas vaginalis lipid A export ATP-binding/permease protein msba, putative 0.0033 0.0044 0.0109
Schistosoma mansoni hypothetical protein 0.0073 0.0174 0.0266
Trypanosoma cruzi ISWI complex protein 0.0028 0.003 0.0062
Echinococcus multilocularis fetal alzheimer antigen, falz 0.0046 0.0088 0.0088
Brugia malayi nuclear receptor NHR-88 0.0041 0.007 0.0117
Mycobacterium tuberculosis Possible oxidoreductase FadB5 0.0062 0.0137 0.0253
Echinococcus multilocularis replication factor c subunit 1 0.0027 0.0025 0.0025
Schistosoma mansoni aldehyde dehydrogenase 0.0131 0.0358 0.0547
Trypanosoma brucei DNA polymerase kappa, putative 0.0029 0.0033 0.0079
Echinococcus granulosus Tubulin beta 2C chain 0.1165 0.3655 0.5582
Brugia malayi tubulin alpha-2 chain 0.0902 0.2816 0.4732
Trypanosoma brucei tubulin delta chain 0.0278 0.0826 0.225
Plasmodium vivax GTP-binding nuclear protein RAN/TC4, putative 0.0021 0.0008 0.0016
Trypanosoma brucei DNA polymerase eta, putative 0.0058 0.0125 0.0329
Mycobacterium ulcerans fatty-acid-CoA ligase FadD9 0.0101 0.0264 0.0525
Giardia lamblia Replication factor C, subunit 1 0.0027 0.0025 0.0049
Brugia malayi Calcitonin receptor-like protein seb-1 0.03 0.0898 0.1509
Mycobacterium ulcerans aldehyde dehydrogenase 0.0131 0.0358 0.0728
Trypanosoma cruzi DNA polymerase kappa, putative 0.0059 0.0128 0.0331
Brugia malayi WGR domain containing protein 0.0754 0.2345 0.394
Trichomonas vaginalis inositol monophosphatase, putative 0.0041 0.0069 0.0178
Echinococcus granulosus tubulin alpha chain 0.0902 0.2816 0.4301
Loa Loa (eye worm) hypothetical protein 0.0025 0.0019 0.0036
Schistosoma mansoni rab6-interacting 0.0019 0.0002 0.0002
Trichomonas vaginalis multidrug resistance protein 1, 2, putative 0.0033 0.0044 0.0109
Loa Loa (eye worm) isocitrate dehydrogenase 0.0032 0.004 0.0077
Schistosoma mansoni nuclear hormone receptor 0.0019 0.0001 0.0002
Echinococcus granulosus L aminoadipate semialdehyde 0.0091 0.0231 0.0353
Mycobacterium ulcerans phenolpthiocerol synthesis type-I polyketide synthase PpsE 0.0658 0.2037 0.433
Echinococcus multilocularis gcn5proteinral control of amino acid synthesis 0.0136 0.0373 0.0373
Leishmania major mitogen activated protein kinase 4, putative;with=GeneDB:LmxM19.1440 0.1068 0.3347 0.9155
Echinococcus multilocularis dna polymerase eta 0.0058 0.0125 0.0125
Echinococcus multilocularis mixed lineage leukemia protein mll 0.0022 0.0009 0.0009
Brugia malayi photoreceptor-specific nuclear receptor 0.0041 0.007 0.0117
Leishmania major prostaglandin f synthase, putative 0.0253 0.0747 0.2027
Trichomonas vaginalis taga, putative 0.0033 0.0044 0.0109
Brugia malayi 3-hydroxyacyl-CoA dehydrogenase type II 0.006 0.0131 0.022
Echinococcus multilocularis aldo keto reductase family 1, member B4 0.0253 0.0747 0.0747
Plasmodium vivax SET domain protein, putative 0.0035 0.005 0.0133
Schistosoma mansoni hypothetical protein 0.1164 0.365 0.5574
Toxoplasma gondii histone lysine acetyltransferase GCN5-B 0.0043 0.0077 0.0191
Echinococcus granulosus multidrug resistance protein 1 0.0023 0.0013 0.002
Plasmodium vivax isocitrate dehydrogenase [NADP], mitochondrial, putative 0.0032 0.004 0.0106
Trypanosoma cruzi aldo-keto reductase 0.0253 0.0747 0.2027
Leishmania major 4-coumarate:coa ligase-like protein 0.0025 0.0019 0.0032
Plasmodium vivax importin-beta 2, putative 0.0056 0.0118 0.0319
Echinococcus multilocularis aldo keto reductase family 1, member B4 0.0253 0.0747 0.0747
Trichomonas vaginalis tubulin beta chain, putative 0.0902 0.2816 0.7702
Schistosoma mansoni ets-related 0.0207 0.0599 0.0915
Entamoeba histolytica acyl-coA synthetase, putative 0.0025 0.0019 0.0032
Plasmodium falciparum malonyl CoA-acyl carrier protein transacylase 0.0063 0.014 0.0379
Wolbachia endosymbiont of Brugia malayi NADPH:quinone reductase 0.0062 0.0137 0.1431
Echinococcus granulosus tubulin delta chain 0.0278 0.0826 0.1261
Toxoplasma gondii 3-oxoacyl-acyl-carrier protein synthase I/II, putative 0.025 0.0736 0.1997
Trichomonas vaginalis conserved hypothetical protein 0.0091 0.023 0.0619
Mycobacterium tuberculosis Possible dehydrogenase 0.0062 0.0137 0.0253
Loa Loa (eye worm) alpha-tubulin 0.0902 0.2816 0.5342
Loa Loa (eye worm) latrophilin receptor protein 2 0.0095 0.0243 0.0461
Echinococcus granulosus ATP dependent DNA helicase Q5 0.0028 0.0029 0.0045
Trypanosoma brucei ATP-dependent 6-phosphofructokinase, glycosomal 0.0106 0.0279 0.0752
Trichomonas vaginalis phosphofructokinase, putative 0.0029 0.0032 0.0074
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0095 0.0243 0.0371
Trypanosoma cruzi mitochondrial DNA polymerase beta, putative 0.0295 0.0882 0.2397
Trypanosoma cruzi isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0032 0.004 0.009
Loa Loa (eye worm) tyrosyl-DNA phosphodiesterase 0.007 0.0164 0.0311
Toxoplasma gondii HEAT repeat-containing protein 0.0056 0.0118 0.0303
Plasmodium vivax hypothetical protein, conserved 0.0027 0.0027 0.0071
Trichomonas vaginalis tubulin epsilon chain, putative 0.1165 0.3655 1
Schistosoma mansoni transcription factor LCR-F1 0.0073 0.0174 0.0266
Mycobacterium tuberculosis Probable conserved transmembrane ATP-binding protein ABC transporter 0.0051 0.0102 0.0178
Leishmania major ATP-dependent phosphofructokinase 0.0106 0.0279 0.0744
Echinococcus granulosus aldo keto reductase family 1 member B4 0.0253 0.0747 0.114
Trypanosoma cruzi FHA domain containing protein, putative 0.0027 0.0025 0.0048
Toxoplasma gondii acyl carrier protein ACP 0.01 0.026 0.0693
Toxoplasma gondii histone lysine demethylase JMJD6a 0.004 0.0069 0.0168
Loa Loa (eye worm) hypothetical protein 0.0305 0.0912 0.173
Trypanosoma brucei alpha tubulin 0.0902 0.2816 0.7702
Schistosoma mansoni phosphatidylserine receptor 0.004 0.0069 0.0105
Plasmodium falciparum tubulin gamma chain 0.064 0.198 0.5416
Trypanosoma cruzi alpha tubulin, putative 0.0902 0.2816 0.77
Trypanosoma brucei DNA polymerase kappa, putative 0.0059 0.0128 0.0339
Onchocerca volvulus Bile acid receptor homolog 0.0041 0.007 0.0124
Brugia malayi Cytochrome P450 family protein 0.0038 0.0061 0.0103
Echinococcus multilocularis peregrin 0.0035 0.0052 0.0052
Loa Loa (eye worm) TK/ROR protein kinase 0.0022 0.001 0.002
Trichomonas vaginalis tubulin alpha chain, putative 0.064 0.198 0.5413
Brugia malayi Latrophilin receptor protein 2 0.0095 0.0243 0.0409
Brugia malayi AMP-binding enzyme family protein 0.0307 0.0918 0.1543
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0055 0.0116 0.022
Trypanosoma cruzi hypothetical protein, conserved 0.0027 0.0025 0.0048
Trypanosoma brucei DNA polymerase kappa, putative 0.0029 0.0033 0.0079
Plasmodium falciparum alpha tubulin 2 0.0902 0.2816 0.7704
Leishmania major mitogen activated protein kinase, putative,map kinase, putative 0.1068 0.3347 0.9155
Echinococcus granulosus tubulin alpha chain 0.0902 0.2816 0.4301
Loa Loa (eye worm) hypothetical protein 0.0019 0.0002 0.0003
Echinococcus granulosus tubulin alpha 1C chain 0.0902 0.2816 0.4301
Brugia malayi nuclear hormone receptor 0.0019 0.0001 0.0002
Brugia malayi jmjC domain containing protein 0.004 0.0069 0.0115
Echinococcus multilocularis aldo keto reductase 0.0253 0.0747 0.0747
Trypanosoma brucei DNA polymerase kappa, putative 0.0059 0.0128 0.0339
Mycobacterium ulcerans quinone oxidoreductase 0.0062 0.0137 0.0253
Trypanosoma brucei mitochondrial DNA polymerase beta-PAK 0.014 0.0386 0.1044
Trypanosoma brucei importin beta-1 subunit, putative 0.0056 0.0118 0.0311
Echinococcus granulosus aldo keto reductase family 1 member B4 0.0253 0.0747 0.114
Entamoeba histolytica P-glycoprotein-1 0.0033 0.0044 0.01
Trypanosoma brucei ISWI complex protein 0.0028 0.003 0.007
Entamoeba histolytica Activator 1 140 kDa subunit, putative 0.0027 0.0025 0.0049
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0055 0.0116 0.0177
Brugia malayi acyl carrier protein, mitochondrial precursor, putative 0.01 0.026 0.0437
Echinococcus granulosus mitogen activated protein kinase 3 0.1068 0.3347 0.5111
Leishmania major ATP-binding cassette protein subfamily G, member 4, putative 0.0061 0.0135 0.035
Mycobacterium ulcerans quinone oxidoreductase 0.0062 0.0137 0.0253
Entamoeba histolytica hypothetical protein 0.0091 0.023 0.0611
Mycobacterium tuberculosis Probable oxidoreductase 0.0062 0.0137 0.0253
Mycobacterium tuberculosis Probable polyketide synthase Pks8 0.0813 0.2534 0.5395
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0055 0.0116 0.0116
Brugia malayi Bromodomain containing protein 0.0035 0.0052 0.0087
Leishmania major prostaglandin f2-alpha synthase/D-arabinose dehydrogenase 0.0253 0.0747 0.2027
Echinococcus granulosus GTP binding nuclear protein Ran 0.0021 0.0008 0.0011
Toxoplasma gondii ATP-binding cassette transporter ABC.B1 0.0033 0.0044 0.01
Schistosoma mansoni methyl-cpg binding protein mbd 0.0031 0.004 0.0062
Plasmodium falciparum ATP-dependent 6-phosphofructokinase 0.0029 0.0032 0.0082
Entamoeba histolytica NADP-dependent alcohol dehydrogenase, putative 0.0062 0.0137 0.0355
Giardia lamblia Beta tubulin 0.1165 0.3655 1
Onchocerca volvulus Dual oxidase homolog 0.0034 0.0049 0.0087
Trypanosoma brucei unspecified product 0.0053 0.0108 0.0283
Trypanosoma cruzi oxidoreductase, putative 0.0062 0.0137 0.0355
Trichomonas vaginalis tubulin alpha-1 chain, putative 0.0362 0.1094 0.2986
Entamoeba histolytica deoxycytidyl transferase, putative 0.0033 0.0045 0.0104
Trichomonas vaginalis aldo-keto reductase, putative 0.0253 0.0747 0.2034
Brugia malayi AMP-binding enzyme family protein 0.0025 0.0019 0.0032
Plasmodium vivax aldehyde reductase, putative 0.0073 0.0174 0.0471
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.0039 0.0064 0.0156
Schistosoma mansoni hypothetical protein 0.0095 0.0243 0.0371
Loa Loa (eye worm) histone methyltransferase 0.0026 0.0024 0.0046
Brugia malayi Nuclear hormone receptor-like 1 0.0022 0.0009 0.0014
Brugia malayi Tubulin beta-1 chain 0.1165 0.3655 0.6141
Brugia malayi PHD-finger family protein 0.0054 0.0112 0.0188
Brugia malayi AMP-binding enzyme family protein 0.0025 0.0019 0.0032
Trypanosoma cruzi DNA polymerase beta thumb, putative 0.0042 0.0072 0.0178
Loa Loa (eye worm) tubulin beta-4 chain 0.1165 0.3655 0.6934
Echinococcus multilocularis tumor protein p63 0.0339 0.1021 0.1021
Toxoplasma gondii beta tubulin 0.1165 0.3655 1
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0041 0.0069 0.017
Schistosoma mansoni zinc finger protein 0.0028 0.003 0.0046
Chlamydia trachomatis malonyl CoA-ACP transacylase 0.0063 0.014 0.1656
Brugia malayi Isocitrate dehydrogenase 0.0032 0.004 0.0068
Brugia malayi nuclear receptor RXR 0.0019 0.0001 0.0002
Echinococcus granulosus aldo keto reductase family 1 member B4 0.0253 0.0747 0.114
Brugia malayi 6-phosphofructokinase 0.0106 0.0279 0.0469
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0041 0.007 0.007
Onchocerca volvulus 0.1739 0.5483 0.9693
Leishmania major beta-ketoacyl synthase family protein, putative,3-oxoacyl-acyl carrier protein synthase ii, putative 0.025 0.0736 0.1997
Echinococcus granulosus fetal alzheimer antigen falz 0.0046 0.0088 0.0134
Loa Loa (eye worm) hypothetical protein 0.0025 0.0018 0.0034
Trypanosoma brucei ABC transporter, putative 0.0061 0.0135 0.0358
Mycobacterium ulcerans cell division protein FtsZ 0.0278 0.0826 0.1731
Mycobacterium leprae PROBABLE 6-PHOSPHOFRUCTOKINASE PFKA (PHOSPHOHEXOKINASE) (PHOSPHOFRUCTOKINASE) 0.0106 0.0279 0.0558
Toxoplasma gondii beta-tubulin, putative 0.1165 0.3655 1
Schistosoma mansoni cpg binding protein 0.0082 0.02 0.0306
Onchocerca volvulus 0.0253 0.0747 0.132
Loa Loa (eye worm) hypothetical protein 0.0025 0.0019 0.0036
Loa Loa (eye worm) tubulin alpha chain 0.0902 0.2816 0.5342
Mycobacterium tuberculosis Polyketide synthase Pks13 0.1487 0.468 1
Schistosoma mansoni 3-hydroxyacyl-CoA dehydrogenase 0.006 0.0131 0.02
Onchocerca volvulus 0.0019 0.0002 0.0003
Echinococcus granulosus peregrin 0.0035 0.0052 0.0079
Schistosoma mansoni smad 0.0024 0.0017 0.0027
Schistosoma mansoni tubulin subunit beta 0.1165 0.3655 0.5582
Trichomonas vaginalis conserved hypothetical protein 0.0091 0.023 0.0619
Mycobacterium tuberculosis Phenolpthiocerol synthesis type-I polyketide synthase PpsC 0.0995 0.3111 0.6635
Echinococcus granulosus WGR domain containing protein 0.026 0.0769 0.1174
Schistosoma mansoni hypothetical protein 0.0597 0.1843 0.2814
Trypanosoma brucei poly(adp-ribose) polymerase 0.0553 0.1704 0.4655
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0041 0.007 0.0117
Leishmania major phosphopantetheinyl transferase-like protein 0.0026 0.0022 0.0039
Trypanosoma cruzi DNA polymerase eta, putative 0.0035 0.0052 0.0122
Trichomonas vaginalis tubulin beta chain, putative 0.0902 0.2816 0.7702
Echinococcus granulosus NADH dehydrogenase 0.01 0.026 0.0398
Onchocerca volvulus Heterochromatin protein 1 homolog 0.004 0.0067 0.0118
Schistosoma mansoni aldo-keto reductase 0.0253 0.0747 0.114
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.006 0.0131 0.0241
Schistosoma mansoni chromobox protein 0.0071 0.0166 0.0254
Onchocerca volvulus Rap guanine nucleotide exchange factor 1 homolog 0.0198 0.0572 0.1012
Loa Loa (eye worm) hypothetical protein 0.0025 0.0019 0.0036
Trypanosoma brucei mitogen activated protein kinase 4, putative 0.1068 0.3347 0.9156
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0045 0.0084 0.0219
Onchocerca volvulus 0.0062 0.0137 0.0242
Plasmodium falciparum AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0039 0.0064 0.0172
Onchocerca volvulus 0.0253 0.0747 0.132
Brugia malayi Nuclear hormone receptor family member nhr-40 0.0041 0.007 0.0117
Brugia malayi MH2 domain containing protein 0.0356 0.1076 0.1808
Toxoplasma gondii oxidoreductase, aldo/keto reductase family protein 0.0073 0.0174 0.0456
Echinococcus granulosus muscleblind protein 0.0305 0.0912 0.1392
Trichomonas vaginalis tubulin, putative 0.0362 0.1094 0.2986
Trichomonas vaginalis ABC transporter, putative 0.0033 0.0044 0.0109
Echinococcus multilocularis tubulin subunit TubB 0.0902 0.2816 0.2816
Mycobacterium ulcerans non-ribosomal peptide synthetase MbtE 0.0108 0.0284 0.0567
Echinococcus multilocularis dna polymerase kappa 0.0059 0.0128 0.0128
Echinococcus multilocularis Acyl carrier protein, mitochondrial 0.01 0.026 0.026
Giardia lamblia Sgs1 DNA helicase, putative 0.0028 0.0029 0.006
Trichomonas vaginalis conserved hypothetical protein 0.0022 0.0009 0.0012
Trichomonas vaginalis conserved hypothetical protein 0.0073 0.0174 0.0464
Schistosoma mansoni retinoic acid receptor RXR 0.0041 0.007 0.0107
Entamoeba histolytica aldose reductase, putative 0.0253 0.0747 0.2027
Onchocerca volvulus Acyl carrier protein, mitochondrial homolog 0.01 0.026 0.046
Echinococcus multilocularis L aminoadipate semialdehyde 0.0091 0.0231 0.0231
Loa Loa (eye worm) ABC transporter 0.0052 0.0106 0.02
Brugia malayi Intermediate filament tail domain containing protein 0.0027 0.0026 0.0044
Echinococcus multilocularis voltage gated potassium channel subunit 0.0073 0.0174 0.0174
Mycobacterium tuberculosis Probable polyketide beta-ketoacyl synthase Pks3 0.0153 0.0426 0.0874
Trichomonas vaginalis tubulin alpha chain, putative 0.0362 0.1094 0.2986
Plasmodium falciparum GTP-binding nuclear protein RAN/TC4 0.0021 0.0008 0.0016
Loa Loa (eye worm) acyl carrier protein 0.0457 0.1398 0.2653
Toxoplasma gondii type I fatty acid synthase, putative 0.0708 0.2198 0.6004
Schistosoma mansoni potassium channel beta 0.0073 0.0174 0.0265
Loa Loa (eye worm) hypothetical protein 0.004 0.0067 0.0127
Toxoplasma gondii inositol(myo)-1(or 4)-monophosphatase 2, putative 0.0041 0.0069 0.017
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.0028 0.0029 0.006
Plasmodium falciparum alpha tubulin 1 0.0902 0.2816 0.7704
Loa Loa (eye worm) hypothetical protein 0.0019 0.0001 0.0002
Plasmodium falciparum conserved Plasmodium protein, unknown function 0.015 0.0419 0.1142
Echinococcus multilocularis chromobox protein 1 0.0071 0.0166 0.0166
Echinococcus multilocularis GTP binding nuclear protein Ran 0.0021 0.0008 0.0008
Loa Loa (eye worm) hypothetical protein 0.0461 0.141 0.2676
Echinococcus multilocularis tubulin alpha chain 0.0902 0.2816 0.2816
Echinococcus granulosus peroxisome assembly protein 26 0.0902 0.2816 0.4301
Brugia malayi ATP-dependent DNA helicase, RecQ family protein 0.0028 0.0029 0.0049
Treponema pallidum exodeoxyribonuclease (exoA) 0.0039 0.0064 0.053
Trypanosoma cruzi poly(ADP-ribose) polymerase, putative 0.0553 0.1704 0.465
Trypanosoma cruzi BRCA1 C Terminus (BRCT) domain containing protein, putative 0.0027 0.0025 0.0048
Wolbachia endosymbiont of Brugia malayi ACP S-malonyltransferase 0.0063 0.014 0.1471
Schistosoma mansoni tubulin subunit beta 0.1165 0.3655 0.5582
Mycobacterium tuberculosis Possible DNA-damage-inducible protein P DinP (DNA polymerase V) (pol IV 2) (DNA nucleotidyltransferase (DNA-directed)) 0.0039 0.0066 0.01
Echinococcus multilocularis mothers against decapentaplegic 5 0.0024 0.0017 0.0017
Echinococcus multilocularis ecdysone induced protein 78C 0.0041 0.007 0.007
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0032 0.0041 0.0062
Mycobacterium ulcerans 3-oxoacyl-(acyl carrier protein) synthase II 0.025 0.0736 0.1538
Echinococcus multilocularis lysine specific demethylase 6a 0.004 0.0069 0.0069
Echinococcus multilocularis aldo keto reductase family 1, member B4 0.0253 0.0747 0.0747
Echinococcus multilocularis microtubule associated protein 2 0.2072 0.6548 0.6548
Toxoplasma gondii tubulin/FtsZ family, GTPase domain-containing protein 0.064 0.198 0.5409
Loa Loa (eye worm) steroid hormone receptor 0.0041 0.007 0.0133
Echinococcus multilocularis ATP binding cassette subfamily B (MDR:TAP) 0.0033 0.0044 0.0044
Schistosoma mansoni nuclear receptor 0.0019 0.0001 0.0002
Giardia lamblia Endonuclease/Exonuclease/phosphatase 0.0039 0.0064 0.0156
Onchocerca volvulus 0.0253 0.0747 0.132
Leishmania major aldo-keto reductase-like protein 0.0253 0.0747 0.2027
Entamoeba histolytica hypothetical protein 0.0069 0.0161 0.0421
Trichomonas vaginalis tubulin alpha chain, putative 0.0362 0.1094 0.2986
Echinococcus multilocularis peroxisome assembly protein 26 0.0902 0.2816 0.2816
Echinococcus multilocularis terminal deoxycytidyl transferase rev1 0.0033 0.0045 0.0045
Mycobacterium ulcerans short-chain dehydrogenase 0.0069 0.0161 0.0305
Echinococcus multilocularis mitogen activated protein kinase 3 0.1068 0.3347 0.3347
Toxoplasma gondii AMP-binding enzyme domain-containing protein 0.0504 0.1546 0.4218
Echinococcus multilocularis inositol monophosphatase 1 0.0041 0.0069 0.0069
Echinococcus multilocularis isocitrate dehydrogenase 0.0032 0.004 0.004
Trypanosoma brucei PAB1-binding protein , putative 0.0025 0.0018 0.0037
Echinococcus multilocularis Smad4 0.0024 0.0017 0.0017
Loa Loa (eye worm) hypothetical protein 0.0019 0.0001 0.0002
Brugia malayi Nuclear hormone receptor family member nhr-31 0.0041 0.007 0.0117
Schistosoma mansoni smdr2 0.0033 0.0044 0.0067
Trypanosoma brucei unspecified product 0.0023 0.0013 0.0022
Leishmania major alpha tubulin 0.0902 0.2816 0.77
Trichomonas vaginalis tubulin gamma chain, putative 0.0278 0.0826 0.225
Toxoplasma gondii isocitrate dehydrogenase 0.0032 0.004 0.009
Leishmania major alpha tubulin 0.0902 0.2816 0.77
Echinococcus granulosus tissue type plasminogen activator 0.0022 0.001 0.0016
Toxoplasma gondii type I fatty acid synthase, putative 0.1057 0.3312 0.9059
Mycobacterium tuberculosis Polyketide synthetase MbtD (polyketide synthase) 0.0306 0.0915 0.1922
Brugia malayi Nuclear hormone receptor family member nhr-1 0.0041 0.007 0.0117
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.0023 0.0015 0.002
Brugia malayi Alcohol dehydrogenase class III 0.0062 0.0137 0.023
Brugia malayi intermediate filament protein 0.0027 0.0026 0.0044
Echinococcus multilocularis Tubulin beta 2C chain 0.1165 0.3655 0.3655
Trichomonas vaginalis tubulin alpha chain, putative 0.0362 0.1094 0.2986
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0032 0.004 0.004
Echinococcus granulosus 6 phosphofructokinase 0.0106 0.0279 0.0426
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0041 0.007 0.0117
Entamoeba histolytica exodeoxyribonuclease III, putative 0.0039 0.0064 0.0156
Brugia malayi ABC transporter family protein 0.0052 0.0106 0.0177
Trichomonas vaginalis glutaminase, putative 0.0273 0.081 0.2207
Leishmania major myo-inositol-1(or 4)-monophosphatase 1, putative 0.0041 0.0069 0.017
Trypanosoma brucei unspecified product 0.0023 0.0013 0.0022
Mycobacterium tuberculosis Inositol-1-monophosphatase SuhB 0.0036 0.0056 0.0079
Trypanosoma cruzi importin beta-1 subunit, putative 0.0045 0.0084 0.0211
Echinococcus multilocularis isocitrate dehydrogenase 2 (NADP+) 0.0032 0.004 0.004
Echinococcus granulosus 5'partial|ATP binding cassette sub family B 0.0032 0.0041 0.0062
Echinococcus multilocularis tubulin alpha chain 0.0902 0.2816 0.2816
Entamoeba histolytica poly(ADP-ribose) polymerase, putative 0.0754 0.2345 0.6409
Trichomonas vaginalis conserved hypothetical protein 0.0027 0.0025 0.0057
Loa Loa (eye worm) oxidoreductase 0.0253 0.0747 0.1417
Loa Loa (eye worm) hypothetical protein 0.0063 0.014 0.0266
Loa Loa (eye worm) 6-phosphofructokinase 0.0106 0.0279 0.0529
Brugia malayi jmjC domain containing protein 0.0208 0.0603 0.1013
Plasmodium falciparum 3-oxoacyl-acyl-carrier protein synthase I/II 0.025 0.0736 0.201
Echinococcus multilocularis tubulin alpha chain 0.0902 0.2816 0.2816
Toxoplasma gondii histone lysine methyltransferase SET1 0.0164 0.0462 0.1245
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0022 0.0009 0.0009
Mycobacterium ulcerans acyl-CoA synthetase 0.0108 0.0284 0.0567
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.03 0.0898 0.1509
Leishmania major DNA polymerase eta, putative 0.0058 0.0125 0.0321
Mycobacterium tuberculosis Conserved hypothetical protein 0.0156 0.0436 0.0895
Brugia malayi polk-prov protein 0.0036 0.0056 0.0093
Echinococcus granulosus Tubulin beta 2C chain 0.1165 0.3655 0.5582
Trypanosoma brucei aldo/keto reductase, putative 0.0073 0.0174 0.0463
Trichomonas vaginalis aldo/keto reductase, putative 0.0253 0.0747 0.2034
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0041 0.007 0.0117
Leishmania major beta tubulin 0.1165 0.3655 1
Echinococcus granulosus lamin dm0 0.0027 0.0026 0.004
Mycobacterium tuberculosis Possible quinone oxidoreductase (NADPH:quinone oxidoreductase) (zeta-crystallin) 0.0062 0.0137 0.0253
Echinococcus multilocularis tubulin alpha 3 chain 0.0902 0.2816 0.2816
Loa Loa (eye worm) GTP-binding nuclear protein RAN/TC4 0.0021 0.0008 0.0014
Mycobacterium tuberculosis Probable polyketide synthase Pks1 0.0715 0.2218 0.4718
Loa Loa (eye worm) MH1 domain-containing protein 0.0024 0.0017 0.0033
Onchocerca volvulus 0.0041 0.007 0.0124
Trichomonas vaginalis CMGC family protein kinase 0.1068 0.3347 0.9156
Echinococcus multilocularis hypothetical protein 0.0902 0.2816 0.2816
Brugia malayi nuclear receptor RXR 0.0022 0.0009 0.0014
Echinococcus granulosus Nuclear hormone receptor HR96 0.0019 0.0001 0.0002
Onchocerca volvulus 0.0062 0.0137 0.0242
Trichomonas vaginalis ATP-binding cassette transporter, putative 0.0033 0.0044 0.0109
Loa Loa (eye worm) fatty acid synthase 0.0981 0.3069 0.5823
Mycobacterium ulcerans DNA polymerase IV 0.0059 0.0128 0.0234
Leishmania major alpha tubulin 0.0902 0.2816 0.77
Trichomonas vaginalis aldo-keto reductase, putative 0.0253 0.0747 0.2034
Leishmania major alpha tubulin 0.0902 0.2816 0.77
Toxoplasma gondii aldose reductase, putative 0.0253 0.0747 0.2027
Entamoeba histolytica hypothetical protein 0.0045 0.0084 0.0211
Echinococcus granulosus ATP binding cassette sub family G 0.0061 0.0135 0.0206
Brugia malayi nuclear receptor NHR-88 0.0019 0.0001 0.0002
Entamoeba histolytica aldose reductase, putative 0.0253 0.0747 0.2027
Echinococcus multilocularis NADH dehydrogenase 0.01 0.026 0.026
Giardia lamblia Aldose reductase 0.0253 0.0747 0.2027
Loa Loa (eye worm) MH2 domain-containing protein 0.0024 0.0017 0.0033
Loa Loa (eye worm) multidrug resistance protein 3 0.0033 0.0044 0.0083
Schistosoma mansoni tubulin subunit gamma 0.064 0.198 0.3024
Trichomonas vaginalis ABC transporter, half transporter, putative 0.0033 0.0044 0.0109
Trypanosoma brucei DNA polymerase kappa, putative 0.0059 0.0128 0.0339
Echinococcus multilocularis Tubulin alpha 1 chain 0.0902 0.2816 0.2816
Loa Loa (eye worm) hypothetical protein 0.0305 0.0912 0.173
Onchocerca volvulus Huntingtin homolog 0.012 0.0322 0.0569
Brugia malayi PHD-finger family protein 0.0027 0.0027 0.0046
Echinococcus multilocularis beta tubulin 0.1165 0.3655 0.3655
Mycobacterium ulcerans quinone reductase Qor 0.0062 0.0137 0.0253
Trichomonas vaginalis alcohol dehydrogenase, putative 0.0062 0.0137 0.0363
Trichomonas vaginalis tubulin alpha chain, putative 0.1165 0.3655 1
Echinococcus multilocularis mitochondrial trans 2 enoyl coenzyme A reductase 0.0062 0.0137 0.0137
Leishmania major alpha tubulin 0.0902 0.2816 0.77
Schistosoma mansoni lamin 0.0027 0.0026 0.004
Trypanosoma brucei DNA polymerase kappa, putative 0.0029 0.0033 0.0079
Onchocerca volvulus DNA ligase 3 homolog 0.0058 0.0126 0.0222
Echinococcus multilocularis thyroid hormone receptor alpha 0.0041 0.007 0.007
Trypanosoma brucei JmjC domain, hydroxylase, putative 0.004 0.0069 0.0176
Entamoeba histolytica recQ family helicase, putative 0.0031 0.0037 0.0082
Trichomonas vaginalis chromobox protein, putative 0.0071 0.0166 0.0443
Schistosoma mansoni chromobox protein 0.0071 0.0166 0.0254
Treponema pallidum DNA ligase (lig) 0.0027 0.0025 0.0041
Loa Loa (eye worm) nuclear receptor nhr-7B 0.0019 0.0001 0.0002
Mycobacterium ulcerans hypothetical protein 0.0156 0.0436 0.0895
Trichomonas vaginalis conserved hypothetical protein 0.0278 0.0826 0.225
Mycobacterium ulcerans phenolpthiocerol synthesis type-I polyketide synthase PpsC 0.1056 0.3308 0.7057
Leishmania major beta tubulin 0.1165 0.3655 1
Loa Loa (eye worm) hypothetical protein 0.0058 0.0125 0.0237
Schistosoma mansoni tubulin subunit alpha 0.0902 0.2816 0.4301
Loa Loa (eye worm) RecQ helicase 0.004 0.0068 0.013
Echinococcus multilocularis bloom syndrome protein 0.004 0.0068 0.0068
Loa Loa (eye worm) hypothetical protein 0.0022 0.0009 0.0016
Trichomonas vaginalis bromodomain-containing protein, putative 0.0043 0.0077 0.0199
Leishmania major beta tubulin 0.1165 0.3655 1
Trypanosoma cruzi tubulin delta chain 0.0278 0.0826 0.2244
Brugia malayi aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase 0.0091 0.0231 0.0389
Leishmania major DNA repair protein, putative 0.0058 0.0126 0.0324
Leishmania major oxidoreductase, putative 0.0062 0.0137 0.0355
Echinococcus granulosus ATP binding cassette subfamily B MDR:TAP 0.0033 0.0044 0.0067
Trypanosoma cruzi NADP-dependent alcohol hydrogenase, putative 0.0062 0.0137 0.0355
Echinococcus multilocularis multidrug resistance protein 1 0.0023 0.0013 0.0013
Leishmania major alpha tubulin 0.0902 0.2816 0.77
Wolbachia endosymbiont of Brugia malayi exonuclease III 0.0039 0.0064 0.053
Brugia malayi oxidoreductase, zinc-binding dehydrogenase family protein 0.0062 0.0137 0.023
Mycobacterium tuberculosis Probable oxidoreductase 0.0253 0.0747 0.1561
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.0039 0.0064 0.0122
Loa Loa (eye worm) nucleolar RNA-associated protein alpha 0.0597 0.1843 0.3496
Trypanosoma cruzi NADP-dependent alcohol hydrogenase, putative 0.0062 0.0137 0.0355
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD9 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0101 0.0264 0.0525
Mycobacterium ulcerans NADP-dependent alcohol dehydrogenase AdhC 0.0062 0.0137 0.0253
Trichomonas vaginalis aldo-keto reductase, putative 0.0253 0.0747 0.2034
Leishmania major alpha tubulin 0.0902 0.2816 0.77
Schistosoma mansoni poly [ADP-ribose] polymerase 0.0754 0.2345 0.3581
Entamoeba histolytica phosphofructokinase, putative 0.0106 0.0279 0.0744
Mycobacterium ulcerans polyketide synthase Pks13 0.1487 0.468 1
Echinococcus granulosus 3 oxoacyl acyl carrier protein synthase 0.025 0.0736 0.1124
Echinococcus multilocularis retinoic acid receptor rxr beta a retinoic acid receptor rxr alpha a retinoic acid receptor rxr alpha 0.0019 0.0001 0.0001
Brugia malayi CXXC zinc finger family protein 0.0082 0.02 0.0337
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0055 0.0116 0.0177
Entamoeba histolytica aldose reductase, putative 0.0253 0.0747 0.2027
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.0041 0.007 0.0133
Trichomonas vaginalis chromosome transmission fidelity factor, putative 0.0027 0.0025 0.0057
Schistosoma mansoni tubulin subunit beta 0.0278 0.0826 0.1261
Schistosoma mansoni hypothetical protein 0.0022 0.001 0.0016
Brugia malayi RNA, U transporter 1 0.0159 0.0447 0.0751
Echinococcus multilocularis 3 oxoacyl (acyl carrier protein) synthase 0.025 0.0736 0.0736
Trypanosoma cruzi ISWI complex protein 0.0028 0.003 0.0062
Brugia malayi Nuclear hormone receptor-like 1 0.0022 0.0009 0.0014
Echinococcus multilocularis lipoxygenase domain containing protein 0.0019 0.0002 0.0002
Echinococcus granulosus Nuclear hormone receptor HR96 0.0019 0.0001 0.0002
Toxoplasma gondii phosphofructokinase PFKII 0.0029 0.0032 0.0066
Echinococcus granulosus smad 0.0024 0.0017 0.0027
Leishmania major mitochondrial DNA polymerase beta-PAK, putative 0.014 0.0386 0.1037
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0045 0.0084 0.0219
Giardia lamblia Pyrophosphate-fructose 6-phosphate 1-phosphotransferase alpha subunit 0.0029 0.0032 0.0066
Loa Loa (eye worm) hypothetical protein 0.0022 0.0009 0.0016
Mycobacterium ulcerans thioesterase TesA 0.0829 0.2583 0.55
Trichomonas vaginalis RNA polymerase II ctd phosphatase, putative 0.0027 0.0025 0.0057
Echinococcus multilocularis aldehyde reductase 0.018 0.0513 0.0513
Trypanosoma cruzi DNA polymerase kappa, putative 0.0059 0.0128 0.0331
Echinococcus multilocularis aldo keto reductase family 1, member B4 0.0253 0.0747 0.0747
Brugia malayi MAP kinase sur-1 0.1068 0.3347 0.5624
Treponema pallidum cell division protein FtsZ 0.0278 0.0826 1
Trypanosoma cruzi ATP-dependent DEAD/H DNA helicase recQ, putative 0.0031 0.0037 0.0082
Entamoeba histolytica hypothetical protein 0.0091 0.023 0.0611
Brugia malayi MH1 domain containing protein 0.0024 0.0017 0.0029
Mycobacterium tuberculosis Probable membrane bound polyketide synthase Pks6 0.1487 0.468 1
Echinococcus granulosus nibrin 0.0027 0.0025 0.0038
Brugia malayi Fli-1 protein 0.0207 0.0599 0.1007
Mycobacterium leprae PHENOLPTHIOCEROL SYNTHESIS TYPE-I POLYKETIDE SYNTHASE PPSE 0.0658 0.2037 0.433
Trichomonas vaginalis 6-phosphofructokinase, putative 0.0029 0.0032 0.0074
Brugia malayi Tubulin beta chain 0.0362 0.1094 0.1839
Echinococcus granulosus Polycystic kidney disease protein 0.0019 0.0002 0.0002
Echinococcus granulosus GPCR family 2 0.0095 0.0243 0.0371
Entamoeba histolytica hypothetical protein 0.0065 0.0146 0.0379
Chlamydia trachomatis 3-oxoacyl-ACP synthase 0.025 0.0736 1
Trypanosoma cruzi tubulin delta chain 0.0278 0.0826 0.2244
Loa Loa (eye worm) nuclear hormone receptor 0.0019 0.0001 0.0002
Loa Loa (eye worm) hypothetical protein 0.0019 0.0001 0.0002
Echinococcus granulosus snurportin 1 0.0597 0.1843 0.2814
Trichomonas vaginalis multidrug resistance protein 1, 2, putative 0.0033 0.0044 0.0109
Trypanosoma brucei importin beta-1 subunit, putative 0.0056 0.0118 0.0311
Plasmodium vivax holo-[acyl-carrier-protein] synthase, putative 0.0026 0.0022 0.0056
Plasmodium falciparum histone acetyltransferase GCN5 0.0035 0.0053 0.014
Leishmania major beta tubulin 0.1165 0.3655 1
Loa Loa (eye worm) hypothetical protein 0.0131 0.0356 0.0676
Mycobacterium tuberculosis holo-[acyl-carrier protein] synthase AcpS (holo-ACP synthase) (CoA:APO-[ACP]pantetheinephosphotransferase) (CoA:APO-[acyl-carrie 0.0026 0.0022 0.0006
Leishmania major oxidoreductase-like protein 0.0062 0.0137 0.0355
Onchocerca volvulus 0.0019 0.0002 0.0003
Trypanosoma brucei ATP-binding cassette protein, putative 0.0061 0.0135 0.0358
Mycobacterium ulcerans exodeoxyribonuclease III protein XthA 0.0039 0.0064 0.0098
Plasmodium falciparum ataxin-2 like protein, putative 0.0025 0.0018 0.0045
Brugia malayi multidrug resistance protein 3 0.0033 0.0044 0.0074
Echinococcus granulosus terminal deoxycytidyl transferase rev1 0.0033 0.0045 0.0069
Brugia malayi Tnks protein 0.0091 0.023 0.0387
Schistosoma mansoni cpg binding protein 0.009 0.0227 0.0346
Giardia lamblia Histone acetyltransferase GCN5 0.0035 0.0053 0.0124
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.0039 0.0064 0.0098
Echinococcus multilocularis nuclear receptor subfamily 4 group A 0.0019 0.0001 0.0001
Trypanosoma cruzi DNA polymerase kappa, putative 0.0059 0.0128 0.0331
Echinococcus granulosus dna polymerase eta 0.0058 0.0125 0.019
Echinococcus multilocularis tankyrase 0.0091 0.023 0.023
Echinococcus multilocularis arachidonate 5 lipoxygenase 0.0116 0.0308 0.0308
Mycobacterium ulcerans oxidoreductase FadB5 0.0062 0.0137 0.0253
Mycobacterium ulcerans zinc-type alcohol dehydrogenase AdhD 0.0062 0.0137 0.0253
Loa Loa (eye worm) glutaminase 0.0273 0.081 0.1537
Echinococcus granulosus TGF beta signal transducer SmadC 0.0024 0.0017 0.0027
Toxoplasma gondii exonuclease III APE 0.0039 0.0064 0.0156
Leishmania major apurinic/apyrimidinic endonuclease-redox protein 0.0039 0.0064 0.0156
Trichomonas vaginalis tubulin, putative 0.0362 0.1094 0.2986
Wolbachia endosymbiont of Brugia malayi NAD-dependent DNA ligase, Lig 0.0027 0.0025 0.0041
Leishmania major nuclear receptor binding factor-like protein 0.0062 0.0137 0.0355
Plasmodium falciparum JmjC domain-containing protein, putative 0.004 0.0069 0.0184
Brugia malayi Nuclear hormone receptor family member nhr-49 0.0041 0.007 0.0117
Plasmodium falciparum ATP-dependent DNA helicase Q1 0.0028 0.0029 0.0076
Schistosoma mansoni coup transcription factor 0.0041 0.007 0.0107
Trypanosoma cruzi acyl transferase-like protein 0.0063 0.014 0.0364
Echinococcus granulosus hypothetical protein 0.0253 0.0747 0.114
Schistosoma mansoni polycystin 1-related 0.0019 0.0002 0.0002
Loa Loa (eye worm) tubulin alpha-2 chain 0.0902 0.2816 0.5342
Toxoplasma gondii ATP-binding cassette G family transporter ABCG84 0.0061 0.0135 0.035
Mycobacterium ulcerans phosphopantetheinyl transferase, PptII 0.0026 0.0022 0.0006
Echinococcus granulosus microtubule associated protein 2 0.2072 0.6548 1
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.0041 0.007 0.0133
Echinococcus granulosus beta tubulin 0.1165 0.3655 0.5582
Trichomonas vaginalis conserved hypothetical protein 0.0091 0.023 0.0619
Echinococcus granulosus replication factor c subunit 1 0.0027 0.0025 0.0038
Plasmodium vivax basic transcription factor 3b, putative 0.0065 0.0146 0.0395
Loa Loa (eye worm) hypothetical protein 0.0022 0.0009 0.0016
Trichomonas vaginalis conserved hypothetical protein 0.0027 0.0025 0.0057
Echinococcus granulosus lipoxygenase domain containing protein 0.0019 0.0002 0.0002
Schistosoma mansoni poly [ADP-ribose] polymerase 0.0462 0.1413 0.2158
Wolbachia endosymbiont of Brugia malayi acyl carrier protein 0.01 0.026 0.2966
Entamoeba histolytica tubulin family protein 0.1165 0.3655 1
Brugia malayi hypothetical protein 0.0019 0.0001 0.0002
Loa Loa (eye worm) fli-1 protein 0.0207 0.0599 0.1137
Echinococcus granulosus poly ADP ribose polymerase 1 0.0754 0.2345 0.3581
Onchocerca volvulus 0.005 0.0098 0.0174
Trichomonas vaginalis abcb9, putative 0.0033 0.0044 0.0109
Trichomonas vaginalis DNA polymerase eta, putative 0.0059 0.0128 0.0339
Mycobacterium tuberculosis Probable quinone reductase Qor (NADPH:quinone reductase) (zeta-crystallin homolog protein) 0.0062 0.0137 0.0253
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0055 0.0116 0.0195
Trichomonas vaginalis aldo-keto reductase, putative 0.0073 0.0174 0.0464
Echinococcus granulosus thyroid hormone receptor alpha 0.0019 0.0001 0.0002
Toxoplasma gondii NAC domain-containing protein 0.0065 0.0146 0.0379
Echinococcus multilocularis aldo keto reductase 0.0253 0.0747 0.0747
Mycobacterium ulcerans transmembrane ABC transporter ATP-binding protein 0.0061 0.0135 0.0249
Loa Loa (eye worm) jmjC domain-containing protein 0.004 0.0069 0.013
Trichomonas vaginalis chromobox protein, putative 0.0071 0.0166 0.0443
Echinococcus multilocularis Tubulin beta 2C chain 0.1165 0.3655 0.3655
Echinococcus multilocularis chromodomain helicase DNA binding protein 4 0.002 0.0003 0.0003
Brugia malayi jmjC domain containing protein 0.004 0.0069 0.0115
Trypanosoma brucei DNA polymerase kappa, putative 0.0059 0.0128 0.0339
Schistosoma mansoni hypothetical protein 0.0051 0.0102 0.0156
Trichomonas vaginalis lipid A export ATP-binding/permease protein msba, putative 0.0033 0.0044 0.0109
Loa Loa (eye worm) 6-phosphofructokinase 0.0106 0.0279 0.0529
Trichomonas vaginalis chromosome transmission fidelity factor, putative 0.0027 0.0025 0.0057
Brugia malayi jmjC domain containing protein 0.004 0.0069 0.0115
Schistosoma mansoni DNA polymerase eta 0.0058 0.0125 0.019
Trichomonas vaginalis dihydrodiol dehydrogenase, putative 0.0253 0.0747 0.2034
Brugia malayi WGR domain containing protein 0.0553 0.1704 0.2863
Mycobacterium leprae conserved hypothetical protein 0.01 0.026 0.0518
Schistosoma mansoni hypothetical protein 0.0038 0.0061 0.0094
Echinococcus granulosus AMP dependent ligase 0.0101 0.0264 0.0402
Schistosoma mansoni multidrug resistance protein 0.0033 0.0044 0.0067
Mycobacterium ulcerans zinc-containing alcohol dehydrogenase NAD dependent AdhB 0.0062 0.0137 0.0253
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.0041 0.007 0.0107
Loa Loa (eye worm) hypothetical protein 0.0032 0.0041 0.0077
Onchocerca volvulus Putative alcohol dehydrogenase 0.0062 0.0137 0.0242
Leishmania major quinone oxidoreductase, putative 0.0062 0.0137 0.0355
Leishmania major hypothetical protein, conserved 0.0022 0.001 0.0008
Mycobacterium ulcerans aldehyde dehydrogenase 0.0131 0.0358 0.0728
Loa Loa (eye worm) hypothetical protein 0.0031 0.0039 0.0075
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.0027 0.0026 0.005
Toxoplasma gondii histone lysine demethylase JMJC1/KDM5D/JARID1D 0.004 0.0069 0.0168
Mycobacterium ulcerans Zn-dependent alcohol dehydrogenase, AdhX 0.0062 0.0137 0.0253
Trypanosoma brucei oxidoreductase, putative 0.0062 0.0137 0.0363
Brugia malayi alpha-tubulin 0.0902 0.2816 0.4732
Echinococcus granulosus poly (ADP ribose) polymerase 0.0069 0.0161 0.0246
Schistosoma mansoni alpha tubulin 0.0902 0.2816 0.4301
Echinococcus multilocularis chromobox protein 1 0.0071 0.0166 0.0166
Trichomonas vaginalis ap endonuclease, putative 0.0039 0.0064 0.0165
Schistosoma mansoni cpg binding protein 0.009 0.0227 0.0346

Activities

Activity type Activity value Assay description Source Reference
Potency (functional) 11.2202 uM PubChem BioAssay. qHTS for Agonist of gsp, the Etiologic Mutation Responsible for Fibrous Dysplasia/McCune-Albright Syndrome: qHTS. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) 89.1251 uM PUBCHEM_BIOASSAY: HTS for Inhibitors of HP1-beta Chromodomain Interactions with Methylated Histone Tails. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID488962] ChEMBL. No reference
Potency (functional) 112.2018 uM PUBCHEM_BIOASSAY: qHTS for Inhibitors of Polymerase Iota. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID588623] ChEMBL. No reference

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

No literature references available for this target.

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