Detailed information for compound 1395077

Basic information

Technical information
  • TDR Targets ID: 1395077
  • Name: 2-(cyclohexylcarbamoyl)cyclohexane-1-carboxyl ic acid
  • MW: 253.337 | Formula: C14H23NO3
  • H donors: 2 H acceptors: 3 LogP: 2.42 Rotable bonds: 4
    Rule of 5 violations (Lipinski): 1
  • SMILES: OC(=O)C1CCCCC1C(=O)NC1CCCCC1
  • InChi: 1S/C14H23NO3/c16-13(15-10-6-2-1-3-7-10)11-8-4-5-9-12(11)14(17)18/h10-12H,1-9H2,(H,15,16)(H,17,18)
  • InChiKey: WFIVKODHWKTHAC-UHFFFAOYSA-N  

Network

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Synonyms

  • 2-[(cyclohexylamino)-oxomethyl]-1-cyclohexanecarboxylic acid
  • Oprea1_353503
  • 2-[(cyclohexylamino)carbonyl]cyclohexanecarboxylic acid
  • MLS000061078
  • SMR000069591
  • 2-Cyclohexylcarbamoyl-cyclohexanecarboxylic acid
  • BAS 00329147
  • Oprea1_713834

Targets

Known targets for this compound

Species Target name Source Bibliographic reference
Homo sapiens GNAS complex locus Starlite/ChEMBL No references

Predicted pathogen targets for this compound

By orthology
Species Potential target Known druggable target/s Ortholog Group
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit Get druggable targets OG5_131088 All targets in OG5_131088
Echinococcus granulosus guanine nucleotide binding protein Gs subunit Get druggable targets OG5_131088 All targets in OG5_131088
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) Get druggable targets OG5_131088 All targets in OG5_131088
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit Get druggable targets OG5_131088 All targets in OG5_131088
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain Get druggable targets OG5_131088 All targets in OG5_131088
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) Get druggable targets OG5_131088 All targets in OG5_131088
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) Get druggable targets OG5_131088 All targets in OG5_131088
Echinococcus granulosus guanine nucleotide binding protein Gs subunit Get druggable targets OG5_131088 All targets in OG5_131088
Schistosoma japonicum ko:K04632 guanine nucleotide binding protein (G protein), alpha stimulating, putative Get druggable targets OG5_131088 All targets in OG5_131088
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative Get druggable targets OG5_131088 All targets in OG5_131088

By sequence similarity to non orthologous known druggable targets
Species Potential target Known druggable target Length Alignment span Identity
Schistosoma mansoni GTP-binding protein alpha subunit gna GNAS complex locus 394 aa 450 aa 28.7 %

Obtained from network model

Ranking Plot


Putative Targets List


Species Potential target Raw Global Species
Echinococcus multilocularis 3 hydroxyacyl coenzyme A dehydrogenase type 2 0.006 0.0131 0.0131
Plasmodium falciparum alpha tubulin 1 0.0902 0.2816 0.7704
Echinococcus multilocularis mothers against decapentaplegic 5 0.0024 0.0017 0.0017
Trichomonas vaginalis aldo-keto reductase, putative 0.0253 0.0747 0.2034
Trypanosoma cruzi NADP-dependent alcohol hydrogenase, putative 0.0062 0.0137 0.0355
Echinococcus granulosus dnaJ subfamily B 0.1164 0.365 0.5574
Onchocerca volvulus Heterochromatin protein 1 homolog 0.0043 0.0076 0.0135
Brugia malayi glutaminase DH11.1 0.0273 0.081 0.1361
Echinococcus multilocularis tubulin beta 1 chain 0.1165 0.3655 0.3655
Echinococcus multilocularis peroxisome assembly protein 26 0.0902 0.2816 0.2816
Loa Loa (eye worm) poly(ADP-ribose) polymerase 0.0362 0.1096 0.2079
Leishmania major hypothetical protein, conserved 0.0058 0.0126 0.0324
Giardia lamblia Kinase, CMGC MAPK 0.1068 0.3347 0.9155
Echinococcus granulosus replication factor c subunit 1 0.0027 0.0025 0.0038
Brugia malayi MH1 domain containing protein 0.0024 0.0017 0.0029
Toxoplasma gondii PHD-finger domain-containing protein 0.0027 0.0027 0.0054
Entamoeba histolytica P-glycoprotein-2 0.0033 0.0044 0.01
Echinococcus granulosus aldo keto reductase 0.0253 0.0747 0.114
Echinococcus multilocularis NADH dehydrogenase 0.01 0.026 0.026
Loa Loa (eye worm) hypothetical protein 0.0019 0.0001 0.0002
Entamoeba histolytica hypothetical protein 0.0091 0.023 0.0611
Schistosoma mansoni hepatocyte nuclear factor 4-alpha (hnf-4-alpha) 0.0019 0.0001 0.0002
Trichomonas vaginalis cat eye syndrome critical region protein 2, cscr2, putative 0.0043 0.0077 0.0199
Loa Loa (eye worm) 3-hydroxyacyl-CoA dehydrogenase type II 0.0052 0.0107 0.0203
Schistosoma mansoni ets-related 0.0207 0.0599 0.0915
Toxoplasma gondii ATP-binding cassette transporter ABC.B1 0.0033 0.0044 0.01
Trichomonas vaginalis aldo-keto reductase, putative 0.0253 0.0747 0.2034
Giardia lamblia Gamma tubulin 0.064 0.198 0.5409
Giardia lamblia ABC transporter 0.006 0.0132 0.034
Mycobacterium ulcerans Type I modular polyketide synthase 0.0995 0.3111 0.6635
Trypanosoma cruzi beta-ketoacyl synthase family protein, putative 0.025 0.0736 0.1997
Schistosoma mansoni chromobox protein 0.0071 0.0166 0.0254
Mycobacterium leprae PHENOLPTHIOCEROL SYNTHESIS TYPE-I POLYKETIDE SYNTHASE PPSC 0.1056 0.3308 0.7057
Echinococcus granulosus Smad4 0.0024 0.0017 0.0027
Echinococcus multilocularis lysine specific demethylase 6a 0.004 0.0069 0.0069
Echinococcus granulosus geminin 0.0504 0.1546 0.2361
Trichomonas vaginalis ABC transporter, putative 0.0033 0.0044 0.0109
Schistosoma mansoni ATP-binding cassette sub-family g2 (white protein) (abcg2) 0.0061 0.0135 0.0206
Treponema pallidum exodeoxyribonuclease (exoA) 0.0039 0.0064 0.053
Plasmodium vivax malonyl CoA-acyl carrier protein transacylase precursor, putative 0.0063 0.014 0.0379
Trichomonas vaginalis lipid A export ATP-binding/permease protein msba, putative 0.0033 0.0044 0.0109
Entamoeba histolytica tyrosyl-DNA phosphodiesterase, putative 0.007 0.0164 0.0428
Trichomonas vaginalis conserved hypothetical protein 0.0091 0.023 0.0619
Trichomonas vaginalis glutaminase, putative 0.0273 0.081 0.2207
Toxoplasma gondii beta-ketoacyl synthase, N-terminal domain-containing protein 0.0645 0.1997 0.5456
Echinococcus granulosus tubulin alpha 1C chain 0.0902 0.2816 0.4301
Trypanosoma cruzi tubulin delta chain 0.0278 0.0826 0.2244
Trypanosoma cruzi JmjC domain, hydroxylase, putative 0.004 0.0069 0.0168
Giardia lamblia Beta tubulin 0.1165 0.3655 1
Wolbachia endosymbiont of Brugia malayi fructose-1,6-bisphosphatase 0.0041 0.0069 0.0591
Onchocerca volvulus 0.0027 0.0026 0.0046
Loa Loa (eye worm) hypothetical protein 0.0041 0.007 0.0133
Schistosoma mansoni cpg binding protein 0.009 0.0227 0.0346
Schistosoma mansoni inositol monophosphatase 0.0041 0.0069 0.0106
Trichomonas vaginalis chromobox protein, putative 0.0071 0.0166 0.0443
Schistosoma mansoni hypothetical protein 0.0504 0.1546 0.2361
Schistosoma mansoni bromodomain containing protein 0.0125 0.0338 0.0516
Echinococcus granulosus Malonyl coenzyme A acyl carrier protein transacylase 0.0063 0.014 0.0214
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0041 0.007 0.0107
Echinococcus granulosus tubulin gamma 1 chain 0.064 0.198 0.3024
Echinococcus multilocularis terminal deoxycytidyl transferase rev1 0.0033 0.0045 0.0045
Schistosoma mansoni smad 0.0024 0.0017 0.0027
Brugia malayi WGR domain containing protein 0.0754 0.2345 0.394
Schistosoma mansoni tyrosyl-DNA phosphodiesterase 0.007 0.0164 0.025
Schistosoma mansoni DNA ligase IV 0.0027 0.0025 0.0038
Mycobacterium leprae PROBABLE POLYKETIDE BETA-KETOACYL SYNTHASE PKS4 0.0153 0.0426 0.0874
Toxoplasma gondii ABC transporter transmembrane region domain-containing protein 0.0033 0.0044 0.01
Schistosoma mansoni serine/threonine protein kinase 0.1068 0.3347 0.5111
Toxoplasma gondii ATPase, AAA family protein 0.0027 0.0025 0.0049
Echinococcus multilocularis ATP binding cassette sub family G 0.0061 0.0135 0.0135
Toxoplasma gondii 4'-phosphopantetheinyl transferase superfamily protein 0.0026 0.0022 0.0039
Brugia malayi Cytochrome P450 family protein 0.0038 0.0061 0.0103
Brugia malayi nuclear hormone receptor family member odr-7 0.0019 0.0001 0.0002
Echinococcus granulosus histone lysine methyltransferase setb 0.0066 0.0151 0.023
Mycobacterium tuberculosis Phenyloxazoline synthase MbtB (phenyloxazoline synthetase) 0.0937 0.2926 0.6238
Treponema pallidum DNA ligase (lig) 0.0027 0.0025 0.0041
Chlamydia trachomatis fructose-6-phosphate phosphotransferase 0.0029 0.0032 0.0135
Trypanosoma brucei DNA polymerase kappa, putative 0.0036 0.0056 0.014
Loa Loa (eye worm) phosphofructokinase 0.0106 0.0279 0.0529
Trypanosoma brucei DNA polymerase IV, putative 0.0059 0.0128 0.0339
Loa Loa (eye worm) blistered cuticle protein 3 0.0034 0.0049 0.0093
Echinococcus multilocularis poly (adp ribose) polymerase 2 0.0553 0.1704 0.1704
Loa Loa (eye worm) Smad1 0.0024 0.0017 0.0033
Loa Loa (eye worm) hypothetical protein 0.0031 0.0039 0.0075
Loa Loa (eye worm) hypothetical protein 0.0056 0.0118 0.0224
Schistosoma mansoni jumonji domain containing protein 0.019 0.0544 0.0831
Schistosoma mansoni smdr2 0.0033 0.0044 0.0067
Mycobacterium tuberculosis Probable thioesterase TesA 0.0829 0.2583 0.55
Plasmodium falciparum JmjC domain-containing protein, putative 0.004 0.0069 0.0184
Echinococcus multilocularis tumor protein p63 0.0339 0.1021 0.1021
Loa Loa (eye worm) hypothetical protein 0.0019 0.0001 0.0002
Brugia malayi Bromodomain containing protein 0.0146 0.0407 0.0683
Entamoeba histolytica hypothetical protein 0.0069 0.0161 0.0421
Mycobacterium tuberculosis Polyketide synthase Pks2 0.0964 0.3014 0.6426
Leishmania major alpha tubulin 0.0902 0.2816 0.77
Brugia malayi nuclear receptor RXR 0.0019 0.0001 0.0002
Schistosoma mansoni phosphatidylserine receptor 0.004 0.0069 0.0105
Entamoeba histolytica alcohol dehydrogenase, putative 0.0073 0.0174 0.0456
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.0041 0.007 0.0107
Trichomonas vaginalis abcb9, putative 0.0033 0.0044 0.0109
Loa Loa (eye worm) intermediate filament protein 0.0027 0.0026 0.005
Echinococcus granulosus poly (ADP ribose) polymerase 0.0069 0.0161 0.0246
Echinococcus multilocularis Tubulin beta 2C chain 0.1165 0.3655 0.3655
Onchocerca volvulus 0.0253 0.0747 0.132
Trichomonas vaginalis tubulin alpha chain, putative 0.0362 0.1094 0.2986
Echinococcus multilocularis importin subunit beta 1 0.0056 0.0118 0.0118
Trypanosoma brucei epsilon tubulin 0.064 0.198 0.5412
Trypanosoma brucei beta tubulin 0.1165 0.3655 1
Trichomonas vaginalis conserved hypothetical protein 0.0091 0.023 0.0619
Trichomonas vaginalis replication factor C large subunit, putative 0.0027 0.0025 0.0057
Giardia lamblia Beta tubulin 0.1165 0.3655 1
Echinococcus multilocularis poly (ADP ribose) polymerase 1 0.0754 0.2345 0.2345
Leishmania major prostaglandin f synthase, putative 0.0253 0.0747 0.2027
Echinococcus multilocularis Transcription factor, JmjC domain containing protein 0.0208 0.0603 0.0603
Brugia malayi Tubulin beta-1 chain 0.1165 0.3655 0.6141
Echinococcus granulosus Nuclear hormone receptor HR96 0.0019 0.0001 0.0002
Trichomonas vaginalis conserved hypothetical protein 0.0091 0.023 0.0619
Mycobacterium ulcerans NADPH quinone oxidoreductase FadB4 0.0062 0.0137 0.0253
Loa Loa (eye worm) jmjC domain-containing protein 0.004 0.0069 0.013
Mycobacterium leprae conserved hypothetical protein 0.01 0.026 0.0518
Onchocerca volvulus 0.0082 0.02 0.0354
Plasmodium falciparum importin beta, putative 0.0056 0.0118 0.0319
Trypanosoma brucei DNA polymerase IV, putative 0.0059 0.0128 0.0339
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0019 0.0001 0.0002
Plasmodium vivax cysteine repeat modular protein 1, putative 0.0022 0.001 0.0024
Trichomonas vaginalis multidrug resistance protein 1, 2, putative 0.0033 0.0044 0.0109
Trypanosoma cruzi ferric reductase transmembrane protein, putative 0.0034 0.0049 0.0114
Echinococcus multilocularis peregrin 0.0035 0.0052 0.0052
Plasmodium falciparum ATP-dependent 6-phosphofructokinase 0.0029 0.0032 0.0082
Trypanosoma cruzi beta tubulin, putative 0.1165 0.3655 1
Trypanosoma brucei transcription factor BTF3, putative 0.0065 0.0146 0.0387
Echinococcus granulosus aldo keto reductase 0.0253 0.0747 0.114
Echinococcus granulosus lysine specific demethylase 5A 0.016 0.0449 0.0685
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.006 0.0131 0.0241
Trypanosoma cruzi importin beta-1 subunit, putative 0.0045 0.0084 0.0211
Loa Loa (eye worm) ICD-1 protein 0.0065 0.0146 0.0277
Loa Loa (eye worm) hypothetical protein 0.0027 0.0025 0.0048
Echinococcus granulosus mitogen activated protein kinase 3 0.1068 0.3347 0.5111
Trypanosoma cruzi cytochrome P450, putative 0.0038 0.0061 0.0148
Echinococcus multilocularis tubulin alpha chain 0.0902 0.2816 0.2816
Echinococcus granulosus GTP binding nuclear protein Ran 0.0021 0.0008 0.0011
Trypanosoma brucei DNA polymerase IV, putative 0.0053 0.0108 0.0283
Trichomonas vaginalis CMGC family protein kinase 0.1068 0.3347 0.9156
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.014 0.0386 0.1037
Mycobacterium tuberculosis Probable polyketide beta-ketoacyl synthase Pks3 0.0153 0.0426 0.0874
Leishmania major myo-inositol-1(or 4)-monophosphatase 1, putative 0.0041 0.0069 0.017
Leishmania major alpha tubulin 0.0902 0.2816 0.77
Schistosoma mansoni alpha tubulin 0.0902 0.2816 0.4301
Schistosoma mansoni nuclear hormone receptor 0.0041 0.007 0.0107
Trypanosoma brucei alpha tubulin 0.0902 0.2816 0.7702
Loa Loa (eye worm) doublecortin family protein 0.0019 0.0002 0.0003
Trichomonas vaginalis tubulin beta chain, putative 0.0902 0.2816 0.7702
Echinococcus multilocularis snurportin 1 0.0597 0.1843 0.1843
Trichomonas vaginalis conserved hypothetical protein 0.0028 0.003 0.007
Trichomonas vaginalis ABC transporter, putative 0.0033 0.0044 0.0109
Echinococcus granulosus chromodomain helicase DNA binding protein 4 0.002 0.0003 0.0005
Plasmodium falciparum malonyl CoA-acyl carrier protein transacylase 0.0063 0.014 0.0379
Echinococcus granulosus retinoic acid receptor rxr beta a 0.0041 0.007 0.0107
Trypanosoma brucei DNA repair protein, putative 0.0058 0.0126 0.0332
Echinococcus granulosus histone acetyltransferase KAT2B 0.0128 0.0347 0.053
Trypanosoma cruzi mitogen activated protein kinase 2, putative 0.1068 0.3347 0.9155
Schistosoma mansoni nuclear receptor 0.0019 0.0001 0.0002
Toxoplasma gondii oxidoreductase, aldo/keto reductase family protein 0.0073 0.0174 0.0456
Toxoplasma gondii alpha-tubulin I, putative 0.0902 0.2816 0.77
Trichomonas vaginalis conserved hypothetical protein 0.0091 0.023 0.0619
Trichomonas vaginalis chromosome transmission fidelity factor, putative 0.0027 0.0025 0.0057
Loa Loa (eye worm) CYP4Cod1 0.0038 0.0061 0.0117
Echinococcus granulosus tubulin alpha 0.064 0.198 0.3024
Loa Loa (eye worm) hypothetical protein 0.0036 0.0056 0.0105
Trichomonas vaginalis inositol monophosphatase, putative 0.0041 0.0069 0.0178
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.0039 0.0064 0.0064
Trypanosoma brucei unspecified product 0.0053 0.0108 0.0283
Echinococcus multilocularis isocitrate dehydrogenase 2 (NADP+) 0.0032 0.004 0.004
Mycobacterium ulcerans DNA polymerase IV 0.0059 0.0128 0.0234
Brugia malayi GTP-binding nuclear protein RAN/TC4 0.0021 0.0008 0.0013
Plasmodium falciparum ATP-dependent DNA helicase Q1 0.0028 0.0029 0.0076
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0026 0.0024 0.0024
Brugia malayi Bloom's syndrome protein homolog 0.004 0.0068 0.0115
Mycobacterium tuberculosis Probable polyketide synthase Pks17 0.0243 0.0715 0.1493
Leishmania major aldehyde reductase, putative,oxidoreductase, putative 0.0253 0.0747 0.2027
Schistosoma mansoni tubulin subunit beta 0.1165 0.3655 0.5582
Trypanosoma brucei DNA polymerase kappa, putative 0.0059 0.0128 0.0339
Trypanosoma cruzi mitochondrial DNA polymerase beta, putative 0.0295 0.0882 0.2397
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.0066 0.0152 0.0152
Brugia malayi oxidoreductase, zinc-binding dehydrogenase family protein 0.0062 0.0137 0.023
Trichomonas vaginalis aldo/keto reductase, putative 0.0253 0.0747 0.2034
Schistosoma mansoni polycystin 1-related 0.0019 0.0002 0.0002
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.003 0.0036 0.0087
Loa Loa (eye worm) bromodomain containing protein 0.0036 0.0054 0.0103
Leishmania major apurinic/apyrimidinic endonuclease-redox protein 0.0039 0.0064 0.0156
Schistosoma mansoni zinc finger protein 0.0044 0.008 0.0123
Trypanosoma cruzi acyl transferase-like protein 0.0063 0.014 0.0364
Trypanosoma brucei RNA helicase, putative 0.0107 0.028 0.0756
Loa Loa (eye worm) hypothetical protein 0.0041 0.007 0.0133
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.003 0.0036 0.0087
Schistosoma mansoni tubulin subunit beta 0.1165 0.3655 0.5582
Leishmania major beta tubulin 0.1165 0.3655 1
Echinococcus multilocularis aldo keto reductase family 1, member B4 0.0253 0.0747 0.0747
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0041 0.007 0.0117
Mycobacterium tuberculosis Probable transmembrane multidrug efflux pump 0.0033 0.0044 0.0054
Schistosoma mansoni ran 0.0021 0.0008 0.0011
Schistosoma mansoni hypothetical protein 0.0019 0.0002 0.0002
Echinococcus multilocularis ATP binding cassette subfamily B (MDR:TAP) 0.0033 0.0044 0.0044
Trypanosoma brucei unspecified product 0.0023 0.0013 0.0022
Plasmodium falciparum basic transcription factor 3b, putative 0.0065 0.0146 0.0395
Trypanosoma brucei epsilon tubulin 0.064 0.198 0.5412
Entamoeba histolytica acyl-CoA synthetase, putative 0.0125 0.0339 0.091
Plasmodium falciparum tubulin gamma chain 0.064 0.198 0.5416
Brugia malayi multidrug resistance protein 3 0.0033 0.0044 0.0074
Trypanosoma cruzi ISWI complex protein 0.0028 0.003 0.0062
Toxoplasma gondii isocitrate dehydrogenase 0.0032 0.004 0.009
Loa Loa (eye worm) hypothetical protein 0.0058 0.0126 0.0239
Wolbachia endosymbiont of Brugia malayi ACP S-malonyltransferase 0.0063 0.014 0.1471
Brugia malayi oxidoreductase, zinc-binding dehydrogenase family protein 0.0062 0.0137 0.023
Echinococcus granulosus tubulin delta chain 0.0278 0.0826 0.1261
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0041 0.007 0.0107
Trypanosoma brucei tubulin delta chain 0.0278 0.0826 0.225
Brugia malayi acyl carrier protein, mitochondrial precursor, putative 0.01 0.026 0.0437
Brugia malayi jmjC domain containing protein 0.004 0.0069 0.0115
Mycobacterium tuberculosis Probable conserved transmembrane ATP-binding protein ABC transporter 0.0051 0.0102 0.0178
Brugia malayi PHD-finger family protein 0.0027 0.0027 0.0046
Mycobacterium tuberculosis Possible DNA-damage-inducible protein P DinP (DNA polymerase V) (pol IV 2) (DNA nucleotidyltransferase (DNA-directed)) 0.0039 0.0066 0.01
Schistosoma mansoni chromobox protein 0.0071 0.0166 0.0254
Toxoplasma gondii aldo/keto reductase family oxidoreductase 0.0073 0.0174 0.0456
Trichomonas vaginalis phosphofructokinase, putative 0.0106 0.0279 0.0752
Schistosoma mansoni cellular tumor antigen P53 0.005 0.0098 0.015
Trichomonas vaginalis tubulin epsilon chain, putative 0.1165 0.3655 1
Mycobacterium ulcerans acyl carrier protein 0.01 0.026 0.0518
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0095 0.0243 0.0371
Schistosoma mansoni coup transcription factor 0.0041 0.007 0.0107
Entamoeba histolytica P-glyco protein 6, putative 0.0033 0.0044 0.01
Plasmodium vivax JmjC domain containing protein 0.004 0.0069 0.0184
Trichomonas vaginalis dihydrodiol dehydrogenase, putative 0.0253 0.0747 0.2034
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.0041 0.007 0.0107
Echinococcus granulosus nuclear receptor subfamily 4 group A 0.0019 0.0001 0.0002
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.0041 0.007 0.007
Loa Loa (eye worm) tubulin beta-4 chain 0.1165 0.3655 0.6934
Schistosoma mansoni cpg binding protein 0.0082 0.02 0.0306
Trypanosoma brucei GTP-binding nuclear protein rtb2, putative 0.0021 0.0008 0.0008
Trichomonas vaginalis conserved hypothetical protein 0.0028 0.003 0.007
Onchocerca volvulus 0.0073 0.0174 0.0307
Loa Loa (eye worm) hypothetical protein 0.0019 0.0001 0.0002
Loa Loa (eye worm) hypothetical protein 0.004 0.0067 0.0127
Loa Loa (eye worm) hypothetical protein 0.0296 0.0882 0.1674
Brugia malayi MAP kinase sur-1 0.1068 0.3347 0.5624
Mycobacterium tuberculosis Probable aldehyde dehydrogenase 0.0131 0.0358 0.0728
Loa Loa (eye worm) alpha-tubulin isotype 2 0.0624 0.193 0.3662
Mycobacterium leprae Conserved hypothetical protein 0.018 0.0513 0.106
Echinococcus multilocularis tyrosyl DNA phosphodiesterase 1 0.007 0.0164 0.0164
Echinococcus multilocularis aldo keto reductase family 1, member B4 0.0253 0.0747 0.0747
Trichomonas vaginalis tubulin, putative 0.1165 0.3655 1
Trypanosoma brucei alpha tubulin 0.0902 0.2816 0.7702
Schistosoma mansoni 3-oxoacyl-[ACP] synthase 0.025 0.0736 0.1124
Loa Loa (eye worm) nuclear receptor NHR-67 0.0019 0.0001 0.0002
Loa Loa (eye worm) tnks protein 0.0091 0.023 0.0437
Onchocerca volvulus 0.1739 0.5483 0.9693
Leishmania major ATP-binding cassette protein subfamily G, member 6, putative 0.0061 0.0135 0.035
Treponema pallidum diphosphate--fructose-6-phosphate 1-phosphotransferase 0.0106 0.0279 0.3197
Echinococcus multilocularis aldo keto reductase 0.0253 0.0747 0.0747
Schistosoma mansoni ubiquitously transcribed sex (X/Y) chromosome tetratricopeptide repeat protein-related 0.004 0.0069 0.0105
Brugia malayi PHD-finger family protein 0.0054 0.0112 0.0188
Schistosoma mansoni mixed-lineage leukemia protein mll 0.003 0.0037 0.0057
Brugia malayi Beta-ketoacyl synthase, N-terminal domain containing protein 0.025 0.0736 0.1237
Trypanosoma brucei oxidoreductase, putative 0.0062 0.0137 0.0363
Wolbachia endosymbiont of Brugia malayi cell division protein FtsZ 0.0278 0.0826 1
Trypanosoma cruzi PAB1-binding protein , putative 0.0025 0.0018 0.0029
Loa Loa (eye worm) hypothetical protein 0.0025 0.0019 0.0036
Leishmania major alpha tubulin 0.0902 0.2816 0.77
Loa Loa (eye worm) jmjC domain-containing protein 0.016 0.0449 0.0851
Loa Loa (eye worm) hypothetical protein 0.0041 0.007 0.0133
Brugia malayi Tubulin alpha chain 0.0902 0.2816 0.4732
Schistosoma mansoni potassium channel beta 0.0073 0.0174 0.0265
Mycobacterium tuberculosis Probable acyl carrier protein AcpA (ACP) 0.01 0.026 0.0518
Echinococcus granulosus Tubulin alpha 1 chain 0.0902 0.2816 0.4301
Trypanosoma brucei beta tubulin 0.1165 0.3655 1
Loa Loa (eye worm) hypothetical protein 0.0022 0.001 0.002
Loa Loa (eye worm) isocitrate dehydrogenase 0.0032 0.004 0.0077
Brugia malayi Nuclear hormone receptor E75 0.0019 0.0001 0.0002
Loa Loa (eye worm) hypothetical protein 0.0025 0.0019 0.0036
Trypanosoma cruzi DNA polymerase kappa, putative 0.0059 0.0128 0.0331
Entamoeba histolytica exodeoxyribonuclease III, putative 0.0039 0.0064 0.0156
Schistosoma mansoni methyl-cpg binding protein mbd 0.0031 0.004 0.0062
Echinococcus multilocularis hypothetical protein 0.0902 0.2816 0.2816
Toxoplasma gondii tubulin/FtsZ family, GTPase domain-containing protein 0.064 0.198 0.5409
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0055 0.0116 0.0177
Trichomonas vaginalis conserved hypothetical protein 0.0091 0.023 0.0619
Toxoplasma gondii ImpB/MucB/SamB family protein 0.0035 0.0052 0.0122
Echinococcus granulosus dna polymerase eta 0.0058 0.0125 0.019
Leishmania major alpha tubulin 0.0902 0.2816 0.77
Leishmania major beta tubulin 0.1165 0.3655 1
Leishmania major 4-coumarate:coa ligase-like protein 0.0025 0.0019 0.0032
Mycobacterium ulcerans zinc-containing alcohol dehydrogenase NAD-dependent AdhB 0.0062 0.0137 0.0253
Mycobacterium tuberculosis Conserved protein 0.0073 0.0174 0.0332
Echinococcus multilocularis aldo keto reductase family 1, member B4 0.0253 0.0747 0.0747
Entamoeba histolytica tubulin gamma chain 0.064 0.198 0.5409
Echinococcus granulosus thyroid hormone receptor alpha 0.0019 0.0001 0.0002
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.03 0.0898 0.1509
Schistosoma mansoni inositol monophosphatase 0.0041 0.0069 0.0106
Brugia malayi Nuclear hormone receptor family member nhr-31 0.0041 0.007 0.0117
Mycobacterium tuberculosis Probable peptide synthetase Nrp (peptide synthase) 0.0108 0.0284 0.0567
Brugia malayi jmjC domain containing protein 0.004 0.0069 0.0115
Trypanosoma brucei mitogen activated protein kinase 4, putative 0.1068 0.3347 0.9156
Trypanosoma cruzi DNA polymerase kappa, putative 0.0059 0.0128 0.0331
Brugia malayi Nuclear hormone receptor family member nhr-14 0.0041 0.007 0.0117
Echinococcus multilocularis muscleblind protein 0.0305 0.0912 0.0912
Echinococcus granulosus ATP binding cassette sub family G 0.0061 0.0135 0.0206
Mycobacterium ulcerans transmembrane ABC transporter ATP-binding protein 0.0061 0.0135 0.0249
Mycobacterium ulcerans zinc-type alcohol dehydrogenase AdhD 0.0062 0.0137 0.0253
Trichomonas vaginalis lipid A export ATP-binding/permease protein msba, putative 0.0033 0.0044 0.0109
Leishmania major cytochrome p450-like protein 0.0038 0.0061 0.0148
Schistosoma mansoni aldo-keto reductase 0.0253 0.0747 0.114
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0041 0.007 0.007
Schistosoma mansoni hypothetical protein 0.1164 0.365 0.5574
Mycobacterium tuberculosis Possible quinone oxidoreductase (NADPH:quinone oxidoreductase) (zeta-crystallin) 0.0062 0.0137 0.0253
Loa Loa (eye worm) oxidoreductase 0.0253 0.0747 0.1417
Trypanosoma brucei PAB1-binding protein , putative 0.0025 0.0018 0.0037
Echinococcus granulosus dna polymerase kappa 0.0059 0.0128 0.0196
Trichomonas vaginalis conserved hypothetical protein 0.0065 0.0146 0.0388
Loa Loa (eye worm) 6-phosphofructokinase 0.0106 0.0279 0.0529
Loa Loa (eye worm) hypothetical protein 0.0087 0.0216 0.041
Trypanosoma cruzi ATP-binding cassette protein, putative 0.0061 0.0135 0.035
Schistosoma mansoni lamin 0.0027 0.0026 0.004
Mycobacterium tuberculosis Probable zinc-type alcohol dehydrogenase AdhD (aldehyde reductase) 0.0062 0.0137 0.0253
Loa Loa (eye worm) hypothetical protein 0.0063 0.014 0.0266
Leishmania major hypothetical protein, conserved 0.03 0.0895 0.2434
Loa Loa (eye worm) heterochromatin protein 1 0.0071 0.0166 0.0315
Echinococcus multilocularis Acyl carrier protein, mitochondrial 0.01 0.026 0.026
Schistosoma mansoni hypothetical protein 0.0205 0.0595 0.0909
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.0041 0.007 0.0133
Brugia malayi Nuclear hormone receptor family member nhr-3 0.0041 0.007 0.0117
Mycobacterium ulcerans phenolpthiocerol synthesis type-I polyketide synthase PpsA 0.08 0.2492 0.5305
Loa Loa (eye worm) hypothetical protein 0.0131 0.0356 0.0676
Plasmodium falciparum multidrug resistance protein 1 0.0033 0.0044 0.0116
Mycobacterium ulcerans aldehyde dehydrogenase 0.0131 0.0358 0.0728
Plasmodium falciparum isocitrate dehydrogenase [NADP], mitochondrial 0.0032 0.004 0.0106
Mycobacterium ulcerans oxidoreductase FadB5 0.0062 0.0137 0.0253
Mycobacterium ulcerans extragenic suppressor protein SuhB 0.0041 0.0069 0.0108
Schistosoma mansoni pol-related 0.0253 0.0747 0.114
Loa Loa (eye worm) hypothetical protein 0.0025 0.0019 0.0036
Echinococcus multilocularis poly (ADP ribose) polymerase 0.016 0.0451 0.0451
Giardia lamblia Histone acetyltransferase GCN5 0.0035 0.0053 0.0124
Schistosoma mansoni smad1 5 8 and 0.0024 0.0017 0.0027
Onchocerca volvulus Alhambra homolog 0.0027 0.0027 0.0048
Entamoeba histolytica hypothetical protein 0.0027 0.0025 0.0048
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.0041 0.007 0.0107
Echinococcus multilocularis ATP binding cassette sub family G 0.0061 0.0135 0.0135
Mycobacterium leprae Probable oxidireductase 0.0062 0.0137 0.0253
Loa Loa (eye worm) hypothetical protein 0.0557 0.1717 0.3257
Loa Loa (eye worm) hypothetical protein 0.0019 0.0001 0.0002
Schistosoma mansoni tubulin subunit beta 0.1165 0.3655 0.5582
Trichomonas vaginalis alcohol dehydrogenase, putative 0.0062 0.0137 0.0363
Entamoeba histolytica hypothetical protein 0.0091 0.023 0.0611
Mycobacterium ulcerans phenolpthiocerol synthesis type-I polyketide synthase PpsC 0.1056 0.3308 0.7057
Leishmania major epsilon tubulin, putative 0.064 0.198 0.5409
Trichomonas vaginalis lipid A export ATP-binding/permease protein msba, putative 0.0033 0.0044 0.0109
Brugia malayi ATP-dependent DNA helicase, RecQ family protein 0.0028 0.0029 0.0049
Giardia lamblia Endonuclease/Exonuclease/phosphatase 0.0039 0.0064 0.0156
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0041 0.007 0.0117
Leishmania major beta tubulin 0.1165 0.3655 1
Echinococcus multilocularis musashi 0.0027 0.0026 0.0026
Loa Loa (eye worm) hypothetical protein 0.0078 0.019 0.0361
Loa Loa (eye worm) histone methyltransferase 0.0026 0.0024 0.0046
Schistosoma mansoni hypothetical protein 0.0051 0.0102 0.0156
Trypanosoma brucei mitochondrial DNA polymerase beta 0.0295 0.0882 0.2403
Leishmania major hypothetical protein, conserved 0.0022 0.001 0.0008
Loa Loa (eye worm) oxidoreductase 0.0253 0.0747 0.1417
Mycobacterium ulcerans NADP-dependent alcohol dehydrogenase AdhC 0.0062 0.0137 0.0253
Loa Loa (eye worm) hypothetical protein 0.0019 0.0002 0.0003
Loa Loa (eye worm) hypothetical protein 0.0027 0.0025 0.0048
Echinococcus multilocularis tubulin, beta 4A class IVa 0.1165 0.3655 0.3655
Leishmania major alpha tubulin 0.0902 0.2816 0.77
Trypanosoma cruzi epsilon tubulin, putative 0.064 0.198 0.5409
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0019 0.0001 0.0001
Mycobacterium leprae cell division protein FtsZ 0.0278 0.0826 0.1731
Schistosoma mansoni topbp1 0.0027 0.0025 0.0038
Toxoplasma gondii hypothetical protein 0.0048 0.0092 0.0231
Schistosoma mansoni multidrug resistance protein 0.0033 0.0044 0.0067
Echinococcus granulosus tankyrase 0.0091 0.023 0.0352
Loa Loa (eye worm) MH1 domain-containing protein 0.0024 0.0017 0.0033
Loa Loa (eye worm) hypothetical protein 0.0027 0.0025 0.0048
Mycobacterium tuberculosis Probable polyketide synthase Pks5 0.0964 0.3014 0.6426
Echinococcus granulosus PHD finger protein rhinoceros 0.0027 0.0027 0.0042
Echinococcus granulosus tubulin alpha 3 chain 0.0902 0.2816 0.4301
Trichomonas vaginalis tubulin beta chain, putative 0.0902 0.2816 0.7702
Echinococcus granulosus multidrug resistance protein 1 0.0033 0.0044 0.0067
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0041 0.007 0.0107
Toxoplasma gondii quinone oxidoreductase, putative 0.0062 0.0137 0.0355
Echinococcus multilocularis aldo keto reductase 0.0253 0.0747 0.0747
Brugia malayi Tubulin alpha chain 0.0278 0.0826 0.1388
Echinococcus granulosus tubulin epsilon chain 0.064 0.198 0.3024
Toxoplasma gondii type I fatty acid synthase 0.0153 0.0426 0.1149
Onchocerca volvulus Putative alcohol dehydrogenase 0.0062 0.0137 0.0242
Toxoplasma gondii poly(ADP-ribose) polymerase catalytic domain-containing protein 0.0781 0.243 0.6642
Echinococcus multilocularis Tubulin alpha 1 chain 0.0902 0.2816 0.2816
Mycobacterium ulcerans multifunctional mycocerosic acid synthase membrane-associated Mas 0.1056 0.3308 0.7057
Entamoeba histolytica aldose reductase, putative 0.0253 0.0747 0.2027
Echinococcus granulosus ATP binding cassette subfamily B MDR:TAP 0.0033 0.0044 0.0067
Trypanosoma brucei aldo-keto reductase, putative 0.0253 0.0747 0.2033
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.003 0.0036 0.0087
Mycobacterium tuberculosis Probable alcohol dehydrogenase AdhA 0.0062 0.0137 0.0253
Trichomonas vaginalis DNA helicase recq1, putative 0.004 0.0068 0.0175
Mycobacterium ulcerans Type I modular polyketide synthase 0.0995 0.3111 0.6635
Onchocerca volvulus 0.0019 0.0002 0.0003
Plasmodium vivax multidrug resistance protein 1, putative 0.0033 0.0044 0.0116
Mycobacterium tuberculosis Probable alcohol dehydrogenase Adh 0.0062 0.0137 0.0253
Schistosoma mansoni tankyrase 0.0091 0.023 0.0352
Echinococcus granulosus aldo keto reductase family 1 member B4 0.0253 0.0747 0.114
Mycobacterium ulcerans malonyl CoA-acyl carrier protein transacylase FabD 0.0063 0.014 0.026
Schistosoma mansoni jumonji/arid domain-containing protein 0.016 0.0449 0.0685
Trichomonas vaginalis alcohol dehydrogenase, putative 0.0062 0.0137 0.0363
Trypanosoma brucei Acyl carrier protein, mitochondrial 0.01 0.026 0.0701
Brugia malayi conserved hypotetical protein 0.0019 0.0001 0.0002
Schistosoma mansoni hypothetical protein 0.01 0.026 0.0398
Trypanosoma brucei poly(adp-ribose) polymerase 0.0553 0.1704 0.4655
Schistosoma mansoni aldehyde dehydrogenase 0.0131 0.0358 0.0547
Schistosoma mansoni tubulin subunit alpha 0.0902 0.2816 0.4301
Mycobacterium leprae PROBABLE NADP-DEPENDENT ALCOHOL DEHYDROGENASE ADHC 0.0062 0.0137 0.0253
Schistosoma mansoni rab geranylgeranyl transferase alpha subunit 0.0033 0.0045 0.0069
Entamoeba histolytica zinc finger protein, putative 0.0091 0.023 0.0611
Mycobacterium tuberculosis Probable polyketide beta-ketoacyl synthase Pks4 0.0153 0.0426 0.0874
Loa Loa (eye worm) glutaminase 0.0273 0.081 0.1537
Brugia malayi nuclear hormone receptor 0.0041 0.007 0.0117
Echinococcus granulosus multidrug resistance protein 1 0.0033 0.0044 0.0067
Echinococcus granulosus aldo keto reductase family 1 member B4 0.0253 0.0747 0.114
Mycobacterium tuberculosis Conserved protein 0.03 0.0895 0.188
Trypanosoma cruzi hypothetical protein, conserved 0.0022 0.001 0.0008
Mycobacterium tuberculosis Cell division protein FtsZ 0.0278 0.0826 0.1731
Onchocerca volvulus Huntingtin homolog 0.012 0.0322 0.0569
Echinococcus multilocularis tankyrase 0.0091 0.023 0.023
Trypanosoma brucei beta tubulin 0.1165 0.3655 1
Loa Loa (eye worm) hypothetical protein 0.0079 0.019 0.0361
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.006 0.0131 0.0241
Mycobacterium tuberculosis Phenolpthiocerol synthesis type-I polyketide synthase PpsD 0.0995 0.3111 0.6635
Echinococcus granulosus aldo keto reductase family 1 member B4 0.0253 0.0747 0.114
Schistosoma mansoni nuclear hormone receptor 0.0019 0.0001 0.0002
Loa Loa (eye worm) nuclear receptor nhr-7B 0.0019 0.0001 0.0002
Onchocerca volvulus 0.0296 0.0882 0.156
Schistosoma mansoni tubulin subunit beta 0.1165 0.3655 0.5582
Trypanosoma brucei aldo/keto reductase, putative 0.0073 0.0174 0.0463
Mycobacterium leprae Polyketide synthase Pks13 0.1487 0.468 1
Loa Loa (eye worm) MH2 domain-containing protein 0.0024 0.0017 0.0033
Loa Loa (eye worm) MH2 domain-containing protein 0.0356 0.1076 0.2041
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.003 0.0036 0.0087
Schistosoma mansoni blooms syndrome DNA helicase 0.0026 0.0023 0.0035
Trichomonas vaginalis tubulin alpha chain, putative 0.0362 0.1094 0.2986
Chlamydia trachomatis fructose-6-phosphate phosphotransferase 0.0029 0.0032 0.0135
Brugia malayi topoisomerase 0.0027 0.0025 0.0042
Leishmania major oxidoreductase, putative 0.0062 0.0137 0.0355
Schistosoma mansoni protein phosphatase 2C 0.004 0.0069 0.0105
Plasmodium falciparum phd finger protein, putative 0.0027 0.0027 0.0071
Mycobacterium leprae Possible oxidoreductase 0.0073 0.0174 0.0332
Brugia malayi MH2 domain containing protein 0.0024 0.0017 0.0029
Plasmodium vivax hypothetical protein, conserved 0.015 0.0419 0.1142
Brugia malayi Isocitrate dehydrogenase 0.0032 0.004 0.0068
Brugia malayi tubulin alpha-2 chain 0.0902 0.2816 0.4732
Onchocerca volvulus 0.0253 0.0747 0.132
Brugia malayi jmjC domain containing protein 0.004 0.0069 0.0115
Entamoeba histolytica poly(ADP-ribose) polymerase, putative 0.0754 0.2345 0.6409
Echinococcus granulosus chromobox protein 1 0.0071 0.0166 0.0254
Giardia lamblia Aldose reductase 0.0253 0.0747 0.2027
Brugia malayi Blistered cuticle protein 3 0.0034 0.0049 0.0082
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0055 0.0116 0.0177
Trypanosoma cruzi ATP-dependent 6-phosphofructokinase, glycosomal 0.0106 0.0279 0.0744
Trichomonas vaginalis ATP-binding cassette transporter, putative 0.0033 0.0044 0.0109
Echinococcus multilocularis tubulin alpha 3 chain 0.0902 0.2816 0.2816
Trypanosoma cruzi transcription factor btf3, putative 0.0065 0.0146 0.0379
Echinococcus multilocularis nibrin 0.0027 0.0025 0.0025
Brugia malayi CXXC zinc finger family protein 0.0082 0.02 0.0337
Toxoplasma gondii beta tubulin 0.1165 0.3655 1
Brugia malayi Pre-SET motif family protein 0.0035 0.005 0.0084
Wolbachia endosymbiont of Brugia malayi NAD-dependent DNA ligase, Lig 0.0027 0.0025 0.0041
Echinococcus multilocularis FTZ F1 alpha 0.0041 0.007 0.007
Echinococcus multilocularis tubulin alpha chain 0.0902 0.2816 0.2816
Loa Loa (eye worm) multidrug resistance protein 3 0.0033 0.0044 0.0083
Chlamydia trachomatis ABC transporter ATP binding protein/permease 0.0033 0.0044 0.031
Echinococcus granulosus fetal alzheimer antigen falz 0.0046 0.0088 0.0134
Mycobacterium tuberculosis Peptide synthetase MbtE (peptide synthase) 0.0108 0.0284 0.0567
Mycobacterium tuberculosis holo-[acyl-carrier protein] synthase AcpS (holo-ACP synthase) (CoA:APO-[ACP]pantetheinephosphotransferase) (CoA:APO-[acyl-carrie 0.0026 0.0022 0.0006
Entamoeba histolytica NADP-dependent alcohol dehydrogenase, putative 0.0062 0.0137 0.0355
Brugia malayi oxidoreductase, zinc-binding dehydrogenase family protein 0.1885 0.5951 1
Trypanosoma brucei DNA polymerase kappa, putative 0.0029 0.0033 0.0079
Onchocerca volvulus 0.0027 0.0026 0.0046
Echinococcus multilocularis bloom syndrome protein 0.004 0.0068 0.0068
Loa Loa (eye worm) hypothetical protein 0.0022 0.0009 0.0016
Schistosoma mansoni [ACP] S-malonyltransferase 0.0063 0.014 0.0214
Brugia malayi jmjC domain containing protein 0.0208 0.0603 0.1013
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0019 0.0001 0.0002
Loa Loa (eye worm) hypothetical protein 0.0027 0.0026 0.005
Mycobacterium leprae PHENOLPTHIOCEROL SYNTHESIS TYPE-I POLYKETIDE SYNTHASE PPSA 0.0995 0.3111 0.6635
Brugia malayi chromobox protein homolog 3 0.004 0.0067 0.0112
Onchocerca volvulus 0.0362 0.1094 0.1935
Entamoeba histolytica deoxycytidyl transferase, putative 0.0033 0.0045 0.0104
Echinococcus multilocularis GPCR, family 2 0.0095 0.0243 0.0243
Brugia malayi ecdysone receptor 0.0019 0.0001 0.0002
Trypanosoma brucei beta-ketoacyl-ACP synthase 0.025 0.0736 0.2004
Leishmania major NADP-dependent alcohol dehydrogenase, putative 0.0062 0.0137 0.0355
Leishmania major mitochondrial DNA polymerase beta-PAK, putative 0.014 0.0386 0.1037
Onchocerca volvulus 0.0022 0.001 0.0018
Mycobacterium ulcerans 4'-phosphopantetheinyl transferase 0.0026 0.0022 0.0006
Trypanosoma brucei DNA polymerase kappa, putative 0.0059 0.0128 0.0339
Entamoeba histolytica hypothetical protein 0.0073 0.0174 0.0457
Entamoeba histolytica phosphofructokinase, putative 0.0106 0.0279 0.0744
Echinococcus granulosus mitogen activated protein kinase 0.1068 0.3347 0.5111
Mycobacterium tuberculosis Polyketide synthetase MbtD (polyketide synthase) 0.0306 0.0915 0.1922
Echinococcus multilocularis aldo keto reductase family 1, member B4 0.0253 0.0747 0.0747
Brugia malayi hypothetical protein 0.0019 0.0001 0.0002
Mycobacterium leprae PHENOLPTHIOCEROL SYNTHESIS TYPE-I POLYKETIDE SYNTHASE PPSD 0.0995 0.3111 0.6635
Plasmodium falciparum ATP-dependent 6-phosphofructokinase 0.0029 0.0032 0.0082
Mycobacterium ulcerans phenyloxazoline synthase MbtB 0.0108 0.0284 0.0567
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0041 0.0069 0.017
Schistosoma mansoni lipoxygenase 0.0116 0.0308 0.0471
Mycobacterium leprae PROBABLE FATTY ACID SYNTHASE FAS (FATTY ACID SYNTHETASE) 0.0312 0.0936 0.1968
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0041 0.007 0.0117
Loa Loa (eye worm) hypothetical protein 0.0019 0.0001 0.0002
Echinococcus granulosus bloom syndrome protein 0.004 0.0068 0.0104
Echinococcus multilocularis aldo keto reductase 0.0253 0.0747 0.0747
Trichomonas vaginalis tubulin beta chain, putative 0.0902 0.2816 0.7702
Onchocerca volvulus 0.0041 0.007 0.0124
Trichomonas vaginalis ap endonuclease, putative 0.0039 0.0064 0.0165
Mycobacterium ulcerans Type I modular polyketide synthase 0.0995 0.3111 0.6635
Schistosoma mansoni Smad4 0.0024 0.0017 0.0027
Mycobacterium leprae Probable polyketide synthase Pks1 0.1056 0.3308 0.7057
Toxoplasma gondii type I fatty acid synthase, putative 0.0708 0.2198 0.6004
Echinococcus multilocularis ATP dependent DNA helicase Q5 0.0028 0.0029 0.0029
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.0028 0.0029 0.006
Trypanosoma brucei epsilon tubulin 0.064 0.198 0.5412
Loa Loa (eye worm) hypothetical protein 0.0095 0.0243 0.0461
Trichomonas vaginalis conserved hypothetical protein 0.0278 0.0826 0.225
Echinococcus granulosus 5'partial|ATP binding cassette sub family B 0.0032 0.0041 0.0062
Trichomonas vaginalis tubulin gamma chain, putative 0.1165 0.3655 1
Loa Loa (eye worm) hypothetical protein 0.004 0.0069 0.013
Brugia malayi AMP-binding enzyme family protein 0.0025 0.0019 0.0032
Schistosoma mansoni RAR-like nuclear receptor 0.0041 0.007 0.0107
Echinococcus granulosus tubulin subunit TubB 0.0902 0.2816 0.4301
Onchocerca volvulus 0.0019 0.0001 0.0002
Mycobacterium ulcerans oxidoreductase 0.0062 0.0137 0.0253
Leishmania major zeta tubulin, putative 0.0278 0.0826 0.2244
Echinococcus multilocularis jumonji domain containing 1A 0.004 0.0069 0.0069
Loa Loa (eye worm) steroid hormone receptor 0.0041 0.007 0.0133
Schistosoma mansoni smad1 5 8 and 0.0024 0.0017 0.0027
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0095 0.0243 0.0243
Brugia malayi orphan nuclear receptor NR2E1 0.0019 0.0001 0.0002
Trichomonas vaginalis lipid A export ATP-binding/permease protein msba, putative 0.0033 0.0044 0.0109
Leishmania major beta tubulin 0.1165 0.3655 1
Mycobacterium tuberculosis Acyl carrier protein (ACP) MbtL 0.01 0.026 0.0518
Mycobacterium ulcerans thioesterase 0.0829 0.2583 0.55
Schistosoma mansoni acetyl-CoA C-acetyltransferase 0.0046 0.0088 0.0134
Mycobacterium tuberculosis Probable short-chain type dehydrogenase/reductase 0.006 0.0131 0.0241
Echinococcus multilocularis aldehyde reductase 0.018 0.0513 0.0513
Schistosoma mansoni multidrug resistance protein 0.0033 0.0044 0.0067
Trypanosoma brucei prostaglandin f synthase 0.0253 0.0747 0.2033
Leishmania major beta tubulin 0.1165 0.3655 1
Trichomonas vaginalis conserved hypothetical protein 0.0091 0.023 0.0619
Brugia malayi oxidoreductase, zinc-binding dehydrogenase family protein 0.0062 0.0137 0.023
Trichomonas vaginalis RNA polymerase II ctd phosphatase, putative 0.0027 0.0025 0.0057
Trypanosoma cruzi tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.007 0.0164 0.0428
Trypanosoma cruzi nuclear receptor binding factor, putative 0.0062 0.0137 0.0355
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.0041 0.007 0.0133
Trichomonas vaginalis lipid A export ATP-binding/permease protein msba, putative 0.0033 0.0044 0.0109
Trypanosoma brucei BRCA1 C Terminus (BRCT) domain containing protein, putative 0.0027 0.0025 0.0057
Echinococcus multilocularis isocitrate dehydrogenase 0.0032 0.004 0.004
Loa Loa (eye worm) glutamate-cysteine ligase modifier subunit 0.0073 0.0174 0.0329
Trypanosoma brucei DNA polymerase kappa, putative 0.0059 0.0128 0.0339
Leishmania major nuclear receptor binding factor-like protein 0.0062 0.0137 0.0355
Loa Loa (eye worm) hypothetical protein 0.0058 0.0125 0.0237
Loa Loa (eye worm) hypothetical protein 0.0019 0.0001 0.0002
Trichomonas vaginalis CMGC family protein kinase 0.1068 0.3347 0.9156
Trypanosoma cruzi tubulin delta chain 0.0278 0.0826 0.2244
Echinococcus granulosus jumonji domain containing 1A 0.004 0.0069 0.0105
Loa Loa (eye worm) hypothetical protein 0.0027 0.0025 0.0047
Leishmania major beta tubulin 0.1165 0.3655 1
Trypanosoma cruzi NADP-dependent alcohol hydrogenase, putative 0.0062 0.0137 0.0355
Schistosoma mansoni multidrug resistance protein 0.0033 0.0044 0.0067
Loa Loa (eye worm) tubulin gamma chain 0.064 0.198 0.3757
Schistosoma mansoni nuclear hormone receptor 0.0019 0.0001 0.0002
Schistosoma mansoni Tr4/Tr2 (homologue) 0.0041 0.007 0.0107
Brugia malayi Importin beta-1 subunit 0.0056 0.0118 0.0199
Brugia malayi 3-hydroxyacyl-CoA dehydrogenase type II 0.006 0.0131 0.022
Giardia lamblia Replication factor C, subunit 1 0.0027 0.0025 0.0049
Schistosoma mansoni hypothetical protein 0.0504 0.1546 0.2361
Trichomonas vaginalis multidrug resistance protein 1, 2, putative 0.0033 0.0044 0.0109
Echinococcus granulosus mixed lineage leukemia protein mll 0.0022 0.0009 0.0013
Brugia malayi hypothetical protein 0.0027 0.0025 0.0042
Leishmania major aldo/keto reductase, putative,aldo/keto reductase family-like protein 0.0073 0.0174 0.0456
Echinococcus multilocularis cpg binding protein 0.009 0.0227 0.0227
Echinococcus multilocularis nuclear receptor subfamily 1 group D 0.0022 0.0009 0.0009
Brugia malayi WGR domain containing protein 0.0553 0.1704 0.2863
Schistosoma mansoni hypothetical protein 0.0095 0.0243 0.0371
Echinococcus granulosus aldo keto reductase family 1 member B4 0.0253 0.0747 0.114
Mycobacterium tuberculosis Probable 6-phosphofructokinase PfkA (phosphohexokinase) (phosphofructokinase) 0.0106 0.0279 0.0558
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0066 0.0151 0.0151
Trichomonas vaginalis aldo-keto reductase, putative 0.0073 0.0174 0.0464
Leishmania major beta tubulin 0.1165 0.3655 1
Trichomonas vaginalis tubulin gamma chain, putative 0.064 0.198 0.5413
Plasmodium vivax tubulin alpha chain, putative 0.0902 0.2816 0.7704
Echinococcus multilocularis phd:f box containing protein 0.004 0.0069 0.0069
Entamoeba histolytica acyl-CoA synthetase, putative 0.0025 0.0019 0.0032
Trypanosoma cruzi isocitrate dehydrogenase, putative 0.0032 0.004 0.009
Echinococcus multilocularis aldo keto reductase family 1, member B4 0.0253 0.0747 0.0747
Trichomonas vaginalis conserved hypothetical protein 0.0091 0.023 0.0619
Echinococcus multilocularis mixed lineage leukemia protein mll 0.0022 0.0009 0.0009
Echinococcus multilocularis thyroid hormone receptor alpha 0.0041 0.007 0.007
Echinococcus multilocularis Tubulin beta 2C chain 0.1165 0.3655 0.3655
Echinococcus granulosus Tubulin beta 2C chain 0.1165 0.3655 0.5582
Toxoplasma gondii beta-1 tubulin, putative 0.1165 0.3655 1
Trichomonas vaginalis conserved hypothetical protein 0.0065 0.0146 0.0388
Echinococcus granulosus intermediate filament protein 0.0027 0.0026 0.004
Toxoplasma gondii AMP-binding enzyme domain-containing protein 0.0504 0.1546 0.4218
Schistosoma mansoni ran 0.0021 0.0008 0.0011
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0032 0.004 0.004
Mycobacterium leprae conserved hypothetical protein 0.0026 0.0022 0.0006
Brugia malayi Steroid receptor seven-up type 2 0.0041 0.007 0.0117
Leishmania major mitogen activated protein kinase, putative,map kinase, putative 0.1068 0.3347 0.9155
Mycobacterium ulcerans polyketide synthase MbtD 0.0306 0.0915 0.1922
Brugia malayi F/Y-rich N-terminus family protein 0.0039 0.0063 0.0106
Brugia malayi ImpB/MucB/SamB family protein 0.0033 0.0045 0.0076
Schistosoma mansoni 3-hydroxyacyl-CoA dehydrogenase 0.006 0.0131 0.02
Mycobacterium ulcerans oxidoreductase 0.0253 0.0747 0.1561
Loa Loa (eye worm) hypothetical protein 0.0027 0.0025 0.0048
Plasmodium falciparum GTP-binding nuclear protein RAN/TC4 0.0021 0.0008 0.0016
Mycobacterium tuberculosis Probable membrane bound polyketide synthase Pks6 0.1487 0.468 1
Leishmania major 3-oxoacyl-(acyl-carrier protein) reductase, putative 0.006 0.0131 0.0339
Toxoplasma gondii HEAT repeat-containing protein 0.0056 0.0118 0.0303
Trichomonas vaginalis conserved hypothetical protein 0.0022 0.0009 0.0012
Onchocerca volvulus 0.0033 0.0044 0.0078
Leishmania major alpha tubulin 0.0902 0.2816 0.77
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0041 0.007 0.0117
Brugia malayi DKFZp564C0469 protein 0.0027 0.0025 0.0042
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0041 0.0069 0.0178
Loa Loa (eye worm) ATP-binding cassette sub-family B member 2 0.0033 0.0044 0.0083
Entamoeba histolytica alcohol dehydrogenase, putative 0.0073 0.0174 0.0456
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.0041 0.007 0.007
Trichomonas vaginalis chromosome transmission fidelity factor, putative 0.0027 0.0025 0.0057
Trichomonas vaginalis conserved hypothetical protein 0.0065 0.0146 0.0388
Mycobacterium ulcerans polyketide synthase MbtC 0.025 0.0736 0.1538
Mycobacterium ulcerans phenolpthiocerol synthesis type-I polyketide synthase PpsD 0.0995 0.3111 0.6635
Echinococcus multilocularis arachidonate 5 lipoxygenase 0.0116 0.0308 0.0308
Giardia lamblia Beta tubulin 0.1165 0.3655 1
Trypanosoma brucei ATP-dependent DEAD/H DNA helicase recQ, putative 0.0031 0.0037 0.009
Schistosoma mansoni zinc finger protein 0.0019 0.0001 0.0002
Echinococcus granulosus tissue type plasminogen activator 0.0022 0.001 0.0016
Loa Loa (eye worm) hypothetical protein 0.0019 0.0001 0.0002
Brugia malayi ABC transporter family protein 0.0052 0.0106 0.0177
Schistosoma mansoni hypothetical protein 0.0095 0.0243 0.0371
Brugia malayi Tubulin beta chain 0.0362 0.1094 0.1839
Trichomonas vaginalis aldo-keto reductase, putative 0.0253 0.0747 0.2034
Echinococcus granulosus poly (ADP ribose) polymerase 0.0191 0.0548 0.0837
Brugia malayi tubulin alpha chain - mouse 0.0902 0.2816 0.4732
Echinococcus granulosus RUN 0.0019 0.0002 0.0002
Leishmania major beta tubulin 0.1165 0.3655 1
Echinococcus granulosus WGR domain containing protein 0.026 0.0769 0.1174
Loa Loa (eye worm) hypothetical protein 0.0041 0.007 0.0133
Mycobacterium ulcerans 3-oxoacyl-(acyl carrier protein) synthase II 0.025 0.0736 0.1538
Brugia malayi ABC transporter family protein 0.0033 0.0044 0.0074
Trypanosoma cruzi oxidoreductase, putative 0.0062 0.0137 0.0355
Trichomonas vaginalis tubulin gamma chain, putative 0.064 0.198 0.5413
Leishmania major hypothetical protein, conserved 0.0028 0.003 0.0062
Trypanosoma cruzi FHA domain containing protein, putative 0.0027 0.0025 0.0048
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0175 0.0496 0.0758
Plasmodium vivax hypothetical protein, conserved 0.0027 0.0027 0.0071
Mycobacterium tuberculosis Probable NADP-dependent alcohol dehydrogenase AdhC 0.0062 0.0137 0.0253
Giardia lamblia Methyltransferase like 2 0.03 0.0895 0.2434
Echinococcus granulosus zinc finger protein 0.0044 0.008 0.0123
Entamoeba histolytica acyl-coA synthetase, putative 0.0025 0.0019 0.0032
Echinococcus multilocularis tubulin epsilon chain 0.064 0.198 0.198
Echinococcus granulosus tubulin alpha chain 0.0902 0.2816 0.4301
Echinococcus granulosus aldo keto reductase family 1 member B4 0.0253 0.0747 0.114
Trypanosoma cruzi tubulin gamma chain 0.064 0.198 0.5409
Brugia malayi hypothetical protein 0.0073 0.0174 0.0292
Brugia malayi tailless protein 0.0019 0.0001 0.0002
Trypanosoma brucei alpha tubulin 0.0902 0.2816 0.7702
Echinococcus multilocularis 6 phosphofructokinase 0.0106 0.0279 0.0279
Echinococcus multilocularis chromobox protein 1 0.0071 0.0166 0.0166
Echinococcus granulosus aldehyde reductase 0.018 0.0513 0.0784
Schistosoma mansoni chromodomain helicase DNA binding protein 0.002 0.0003 0.0005
Echinococcus multilocularis muscleblind protein 1 0.0305 0.0912 0.0912
Trichomonas vaginalis tubulin epsilon chain, putative 0.0902 0.2816 0.7702
Leishmania major beta tubulin 0.1165 0.3655 1
Echinococcus granulosus tubulin alpha 3 chain 0.0902 0.2816 0.4301
Schistosoma mansoni phd/f-box containing protein 0.004 0.0069 0.0105
Trichomonas vaginalis ATP-binding cassette transporter, putative 0.0023 0.0013 0.0024
Loa Loa (eye worm) nucleolar RNA-associated protein alpha 0.0597 0.1843 0.3496
Trypanosoma cruzi aldo/keto reductase, putative 0.0253 0.0747 0.2027
Brugia malayi beta-tubulin, identical 0.1165 0.3655 0.6141
Toxoplasma gondii phosphofructokinase PFKII 0.0029 0.0032 0.0066
Loa Loa (eye worm) phosphopantetheine attachment site family protein 0.01 0.026 0.0494
Loa Loa (eye worm) hypothetical protein 0.0305 0.0912 0.173
Echinococcus multilocularis Tubulin beta 2C chain 0.1165 0.3655 0.3655
Treponema pallidum cell division protein FtsZ 0.0278 0.0826 1
Echinococcus granulosus ATP dependent DNA helicase Q1 0.0028 0.0029 0.0045
Trichomonas vaginalis DNA helicase recq, putative 0.004 0.0068 0.0175
Mycobacterium ulcerans 3-oxoacyl-(acyl carrier protein) synthase II 0.025 0.0736 0.1538
Trichomonas vaginalis set domain proteins, putative 0.0262 0.0775 0.2112
Wolbachia endosymbiont of Brugia malayi 3-oxoacyl-ACP synthase 0.025 0.0736 0.8882
Leishmania major hypothetical protein, conserved 0.004 0.0069 0.0168
Echinococcus multilocularis transcription factor btf3 0.0065 0.0146 0.0146
Plasmodium falciparum histone acetyltransferase GCN5 0.0035 0.0053 0.014
Loa Loa (eye worm) acyl carrier protein 0.01 0.026 0.0494
Toxoplasma gondii acyl carrier protein ACP 0.01 0.026 0.0693
Trichomonas vaginalis aldo/keto reductase, putative 0.0253 0.0747 0.2034
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0046 0.0087 0.0133
Entamoeba histolytica transcription factor BTF3, putative 0.0065 0.0146 0.0379
Mycobacterium leprae Probable multifunctional mycocerosic acid synthase membrane associated enzyme Mas 0.1056 0.3308 0.7057
Echinococcus granulosus terminal deoxycytidyl transferase rev1 0.0033 0.0045 0.0069
Brugia malayi hypothetical protein 0.0022 0.0009 0.0014
Loa Loa (eye worm) hypothetical protein 0.0027 0.0025 0.0048
Trichomonas vaginalis tubulin alpha chain, putative 0.1165 0.3655 1
Echinococcus multilocularis beta tubulin 0.1165 0.3655 0.3655
Schistosoma mansoni tubulin subunit epsilon 0.064 0.198 0.3024
Brugia malayi polk-prov protein 0.0036 0.0056 0.0093
Leishmania major ATP-binding cassette protein subfamily G, member 4, putative 0.0061 0.0135 0.035
Echinococcus granulosus aldo keto reductase family 1 member B4 0.0253 0.0747 0.114
Loa Loa (eye worm) hypothetical protein 0.0019 0.0001 0.0002
Loa Loa (eye worm) fatty acid synthase 0.0981 0.3069 0.5823
Schistosoma mansoni methyl-cpg binding protein mbd 0.0031 0.004 0.0062
Trypanosoma brucei ATP-binding cassette protein, putative 0.0061 0.0135 0.0358
Loa Loa (eye worm) tubulin beta chain 0.1165 0.3655 0.6934
Echinococcus granulosus aldo keto reductase family 1 member B4 0.0253 0.0747 0.114
Plasmodium falciparum ataxin-2 like protein, putative 0.0025 0.0018 0.0045
Mycobacterium tuberculosis Phenolpthiocerol synthesis type-I polyketide synthase PpsC 0.0995 0.3111 0.6635
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0108 0.0284 0.0476
Mycobacterium ulcerans aldehyde dehydrogenase 0.0131 0.0358 0.0728
Loa Loa (eye worm) CXXC zinc finger family protein 0.0082 0.02 0.038
Echinococcus multilocularis tubulin subunit beta 0.1165 0.3655 0.3655
Echinococcus granulosus mothers against decapentaplegic 5 0.0024 0.0017 0.0027
Echinococcus multilocularis RUN 0.0019 0.0002 0.0002
Schistosoma mansoni aldo-keto reductase 0.0253 0.0747 0.114
Brugia malayi N-terminal motif family protein 0.0198 0.0572 0.0962
Echinococcus multilocularis tubulin alpha chain 0.0902 0.2816 0.2816
Toxoplasma gondii type I fatty acid synthase, putative 0.1057 0.3312 0.9059
Echinococcus granulosus nuclear receptor subfamily 1 group D 0.0022 0.0009 0.0013
Brugia malayi Tubulin gamma chain 0.064 0.198 0.3327
Echinococcus multilocularis chromobox protein 1 0.0071 0.0166 0.0166
Loa Loa (eye worm) tubulin beta-2A chain 0.1165 0.3655 0.6934
Brugia malayi nuclear receptor NHR-88 0.0041 0.007 0.0117
Loa Loa (eye worm) tubulin alpha 2 0.0262 0.0776 0.1472
Echinococcus multilocularis JmjC domain containing protein 4 0.004 0.0069 0.0069
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.0039 0.0064 0.0156
Brugia malayi nuclear hormone receptor 0.0019 0.0001 0.0002
Brugia malayi Nuclear hormone receptor family member nhr-41 0.0041 0.007 0.0117
Leishmania major DNA repair protein, putative 0.0058 0.0126 0.0324
Echinococcus multilocularis inositol monophosphatase 1 0.0041 0.0069 0.0069
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0019 0.0001 0.0001
Brugia malayi intermediate filament protein 0.0027 0.0026 0.0044
Mycobacterium ulcerans zinc-containing alcohol dehydrogenase NAD dependent AdhB 0.0062 0.0137 0.0253
Leishmania major alpha tubulin 0.0902 0.2816 0.77
Brugia malayi exodeoxyribonuclease III family protein 0.0039 0.0064 0.0108
Entamoeba histolytica tubulin family protein 0.1165 0.3655 1
Loa Loa (eye worm) hypothetical protein 0.0062 0.0137 0.026
Trypanosoma cruzi poly(ADP-ribose) polymerase, putative 0.0553 0.1704 0.465
Schistosoma mansoni microtubule-associated protein tau 0.2072 0.6548 1
Trypanosoma brucei ferric reductase transmembrane protein, putative 0.0034 0.0049 0.0122
Echinococcus multilocularis tubulin alpha 0.064 0.198 0.198
Schistosoma mansoni hypothetical protein 0.0027 0.0027 0.0042
Loa Loa (eye worm) DR-78 0.0019 0.0001 0.0002
Mycobacterium ulcerans oxidoreductase 0.0062 0.0137 0.0253
Brugia malayi jmjC domain containing protein 0.004 0.0069 0.0115
Schistosoma mansoni alpha tubulin 0.0902 0.2816 0.4301
Entamoeba histolytica tubulin family protein 0.1165 0.3655 1
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0055 0.0116 0.0195
Echinococcus multilocularis lysine specific demethylase 5A 0.0151 0.0423 0.0423
Echinococcus multilocularis lipoxygenase domain containing protein 0.0019 0.0002 0.0002
Trypanosoma brucei DNA polymerase kappa, putative 0.0039 0.0066 0.0168
Schistosoma mansoni lipoxygenase 0.0081 0.0198 0.0302
Leishmania major alpha tubulin 0.0902 0.2816 0.77
Trypanosoma brucei DNA polymerase kappa, putative 0.0059 0.0128 0.0339
Trichomonas vaginalis DNA helicase recq, putative 0.0031 0.0037 0.009
Brugia malayi Bromodomain containing protein 0.0035 0.0052 0.0087
Leishmania major hypothetical protein, conserved 0.0025 0.0018 0.0029
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0045 0.0084 0.0219
Trichomonas vaginalis CMGC family protein kinase 0.1068 0.3347 0.9156
Entamoeba histolytica phosphofructokinase, putative 0.0106 0.0279 0.0744
Toxoplasma gondii ATP-binding cassette G family transporter ABCG84 0.0061 0.0135 0.035
Echinococcus multilocularis smad 0.0024 0.0017 0.0017
Brugia malayi Muscleblind-like protein 0.0305 0.0912 0.1532
Trichomonas vaginalis phosphofructokinase, putative 0.0106 0.0279 0.0752
Trypanosoma cruzi transcription factor btf3, putative 0.0065 0.0146 0.0379
Brugia malayi acetyltransferase, GNAT family protein 0.0136 0.0373 0.0626
Echinococcus granulosus Nuclear hormone receptor HR96 0.0019 0.0001 0.0002
Onchocerca volvulus 0.0027 0.0025 0.0045
Trichomonas vaginalis conserved hypothetical protein 0.03 0.0895 0.2441
Onchocerca volvulus Dual oxidase homolog 0.0034 0.0049 0.0087
Echinococcus granulosus chromobox protein 1 0.0071 0.0166 0.0254
Brugia malayi alpha-tubulin 0.0902 0.2816 0.4732
Echinococcus granulosus lipoxygenase domain containing protein 0.0019 0.0002 0.0002
Loa Loa (eye worm) beta-ketoacyl synthase domain-containing protein 0.025 0.0736 0.1396
Onchocerca volvulus 0.0062 0.0137 0.0242
Plasmodium vivax tubulin epsilon chain, putative 0.064 0.198 0.5416
Mycobacterium ulcerans polyketide synthase 0.0995 0.3111 0.6635
Loa Loa (eye worm) tyrosyl-DNA phosphodiesterase 0.007 0.0164 0.0311
Wolbachia endosymbiont of Brugia malayi NADPH:quinone reductase 0.0062 0.0137 0.1431
Trypanosoma brucei beta tubulin 0.1165 0.3655 1
Onchocerca volvulus 0.0253 0.0747 0.132
Leishmania major DNA polymerase eta, putative 0.0035 0.0052 0.0122
Trichomonas vaginalis RNA polymerase II ctd phosphatase, putative 0.0027 0.0025 0.0057
Brugia malayi Fli-1 protein 0.0207 0.0599 0.1007
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.0118 0.0317 0.0317
Echinococcus granulosus poly adp ribose polymerase 2 0.0553 0.1704 0.2602
Plasmodium vivax 6-phosphofructokinase, putative 0.0029 0.0032 0.0082
Toxoplasma gondii aldose reductase, putative 0.0253 0.0747 0.2027
Toxoplasma gondii CMGC kinase, MAPK family (ERK) MAPK-1 0.1068 0.3347 0.9155
Onchocerca volvulus 0.0937 0.2926 0.5173
Trichomonas vaginalis ATP-binding cassette transporter, putative 0.0033 0.0044 0.0109
Leishmania major gamma-tubulin 0.064 0.198 0.5409
Entamoeba histolytica Activator 1 140 kDa subunit, putative 0.0027 0.0025 0.0049
Trypanosoma cruzi BRCA1 C Terminus (BRCT) domain containing protein, putative 0.0027 0.0025 0.0048
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0055 0.0116 0.0116
Plasmodium vivax tubulin gamma chain, putative 0.064 0.198 0.5416
Echinococcus granulosus tubulin alpha chain 0.0902 0.2816 0.4301
Brugia malayi ADP-specific Phosphofructokinase/Glucokinase conserved region family protein 0.0063 0.014 0.0235
Brugia malayi Heterochromatin protein 1 0.0071 0.0166 0.0279
Brugia malayi Nuclear hormone receptor-like 1 0.0022 0.0009 0.0014
Loa Loa (eye worm) tubulin alpha-2 chain 0.0902 0.2816 0.5342
Leishmania major hypothetical protein, conserved 0.0063 0.014 0.0364
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0035 0.005 0.005
Echinococcus granulosus transcription factor btf3 0.0065 0.0146 0.0223
Schistosoma mansoni bromodomain-containing nuclear protein 1 brd1 0.0027 0.0027 0.0042
Echinococcus granulosus tubulin alpha 1C chain 0.0902 0.2816 0.4301
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.0039 0.0064 0.0098
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.0023 0.0015 0.002
Plasmodium vivax ADP-dependent DNA helicase RecQ, putative 0.0024 0.0016 0.0041
Entamoeba histolytica recQ family helicase, putative 0.0031 0.0037 0.0082
Onchocerca volvulus Huntingtin homolog 0.012 0.0322 0.0569
Trichomonas vaginalis phosphofructokinase, putative 0.0029 0.0032 0.0074
Mycobacterium leprae Probable fatty-acid-CoA ligase FadD9 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0101 0.0264 0.0525
Leishmania major alpha tubulin 0.0902 0.2816 0.77
Echinococcus granulosus phd:f box containing protein 0.004 0.0069 0.0105
Loa Loa (eye worm) hypothetical protein 0.03 0.0898 0.1704
Loa Loa (eye worm) tubulin alpha chain 0.0902 0.2816 0.5342
Loa Loa (eye worm) hypothetical protein 0.0058 0.0126 0.0238
Echinococcus multilocularis retinoic acid receptor rxr beta a retinoic acid receptor rxr alpha a retinoic acid receptor rxr alpha 0.0019 0.0001 0.0001
Schistosoma mansoni intermediate filament proteins 0.0027 0.0026 0.004
Mycobacterium tuberculosis Polyketide synthase Pks12 0.1056 0.3308 0.7057
Brugia malayi jmjC domain containing protein 0.016 0.0449 0.0754
Echinococcus granulosus ATP binding cassette sub family G 0.0061 0.0135 0.0206
Leishmania major zinc binding dehydrogenase-like protein 0.0062 0.0137 0.0355
Mycobacterium leprae PROBABLE 6-PHOSPHOFRUCTOKINASE PFKA (PHOSPHOHEXOKINASE) (PHOSPHOFRUCTOKINASE) 0.0106 0.0279 0.0558
Trypanosoma brucei importin beta-1 subunit, putative 0.0056 0.0118 0.0311
Mycobacterium tuberculosis Probable oxidoreductase 0.0253 0.0747 0.1561
Trypanosoma brucei ISWI complex protein 0.0028 0.003 0.007
Trypanosoma cruzi cytochrome P450, putative 0.0038 0.0061 0.0148
Chlamydia trachomatis malonyl CoA-ACP transacylase 0.0063 0.014 0.1656
Echinococcus granulosus poly (ADP ribose) polymerase 0.026 0.0769 0.1174
Mycobacterium tuberculosis Possible dehydrogenase 0.0062 0.0137 0.0253
Mycobacterium tuberculosis Probable polyketide synthase Pks15 0.0402 0.1222 0.2582
Loa Loa (eye worm) hypothetical protein 0.0062 0.0137 0.026
Loa Loa (eye worm) hypothetical protein 0.0027 0.0025 0.0048
Trypanosoma brucei zeta tubulin 0.0278 0.0826 0.225
Brugia malayi oxidoreductase, aldo/keto reductase family protein 0.0253 0.0747 0.1255
Echinococcus granulosus jumonji domain containing protein 0.0038 0.0062 0.0094
Mycobacterium tuberculosis Probable fatty acid synthase Fas (fatty acid synthetase) 0.0312 0.0936 0.1968
Mycobacterium tuberculosis Inositol-1-monophosphatase SuhB 0.0036 0.0056 0.0079
Brugia malayi Nuclear hormone receptor E75 0.0019 0.0001 0.0002
Echinococcus granulosus 3 hydroxyacyl coenzyme A dehydrogenase type 2 0.006 0.0131 0.02
Entamoeba histolytica aldose reductase, putative 0.0253 0.0747 0.2027
Brugia malayi Pax transcription activation domain interacting protein 0.0027 0.0025 0.0042
Toxoplasma gondii exonuclease III APE 0.0039 0.0064 0.0156
Mycobacterium tuberculosis Phenolpthiocerol synthesis type-I polyketide synthase PpsB 0.0153 0.0426 0.0874
Trichomonas vaginalis alcohol dehydrogenase, putative 0.0073 0.0174 0.0464
Trypanosoma cruzi mitochondrial DNA polymerase beta, putative 0.0295 0.0882 0.2397
Loa Loa (eye worm) hypothetical protein 0.1672 0.5271 1
Mycobacterium tuberculosis Probable multifunctional mycocerosic acid synthase membrane-associated Mas 0.1056 0.3308 0.7057
Loa Loa (eye worm) ATP-dependent DNA helicase 0.0028 0.0029 0.0055
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0041 0.007 0.007
Schistosoma mansoni hypothetical protein 0.0073 0.0174 0.0266
Leishmania major beta tubulin 0.1165 0.3655 1
Entamoeba histolytica hypothetical protein 0.0091 0.023 0.0611
Entamoeba histolytica hypothetical protein 0.0073 0.0174 0.0457
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0026 0.0024 0.0037
Leishmania major phosphopantetheinyl transferase-like protein 0.0026 0.0022 0.0039
Entamoeba histolytica pyrophosphate-dependent phosphofructokinase 0.0029 0.0032 0.0066
Schistosoma mansoni 6-phosphofructokinase 0.0106 0.0279 0.0426
Mycobacterium ulcerans polyketide synthase Pks9 0.0658 0.2037 0.433
Loa Loa (eye worm) oxidoreductase 0.0253 0.0747 0.1417
Trichomonas vaginalis lipid A export ATP-binding/permease protein msba, putative 0.0033 0.0044 0.0109
Mycobacterium tuberculosis Conserved hypothetical protein 0.0156 0.0436 0.0895
Loa Loa (eye worm) nuclear hormone receptor 0.0019 0.0001 0.0002
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0066 0.0151 0.023
Brugia malayi Alcohol dehydrogenase class III 0.0062 0.0137 0.023
Trypanosoma brucei isocitrate dehydrogenase, putative 0.0032 0.004 0.0098
Loa Loa (eye worm) GTP-binding nuclear protein RAN/TC4 0.0021 0.0008 0.0014
Chlamydia trachomatis 3-oxoacyl-ACP synthase 0.025 0.0736 1
Echinococcus granulosus Tubulin beta 2C chain 0.1165 0.3655 0.5582
Leishmania major zinc-binding dehydrogenase-like protein 0.0062 0.0137 0.0355
Loa Loa (eye worm) glutaminase 2 0.0273 0.081 0.1537
Loa Loa (eye worm) hypothetical protein 0.012 0.0322 0.0611
Brugia malayi Cell division protein ftsZ 0.0278 0.0826 0.1388
Toxoplasma gondii histone lysine demethylase JMJC1/KDM5D/JARID1D 0.004 0.0069 0.0168
Mycobacterium ulcerans quinone oxidoreductase 0.0062 0.0137 0.0253
Leishmania major DNA polymerase eta, putative 0.0058 0.0125 0.0321
Trichomonas vaginalis aldo/keto reductase, putative 0.0253 0.0747 0.2034
Loa Loa (eye worm) pigment dispersing factor receptor c 0.03 0.0898 0.1704
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.003 0.0036 0.0087
Onchocerca volvulus 0.005 0.0098 0.0174
Brugia malayi nuclear receptor subfamily 1, group D, member 1, putative 0.0019 0.0001 0.0002
Trichomonas vaginalis abcb9, putative 0.0033 0.0044 0.0109
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0022 0.0009 0.0013
Trichomonas vaginalis conserved hypothetical protein 0.0278 0.0826 0.225
Trichomonas vaginalis phosphofructokinase, putative 0.0029 0.0032 0.0074
Leishmania major beta tubulin 0.1165 0.3655 1
Echinococcus multilocularis lamin dm0 0.0027 0.0026 0.0026
Schistosoma mansoni nuclear receptor 0.0019 0.0001 0.0002
Loa Loa (eye worm) hypothetical protein 0.0019 0.0001 0.0002
Plasmodium vivax basic transcription factor 3b, putative 0.0065 0.0146 0.0395
Trichomonas vaginalis aldo-keto reductase, putative 0.0073 0.0174 0.0464
Loa Loa (eye worm) hypothetical protein 0.0027 0.0027 0.005
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0041 0.0069 0.0178
Brugia malayi 6-phosphofructokinase 0.0107 0.0282 0.0474
Trichomonas vaginalis conserved hypothetical protein 0.0091 0.023 0.0619
Mycobacterium ulcerans polyketide synthase 0.1056 0.3308 0.7057
Leishmania major beta tubulin 0.1165 0.3655 1
Loa Loa (eye worm) tubulin alpha 2 0.0624 0.193 0.3662
Plasmodium falciparum AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0039 0.0064 0.0172
Echinococcus granulosus Jumonji AT rich interactive domain 1B 0.0049 0.0095 0.0145
Loa Loa (eye worm) jmjC domain-containing protein 0.004 0.0069 0.013
Echinococcus granulosus tubulin alpha chain 0.0902 0.2816 0.4301
Leishmania major 4-coumarate:coa ligase-like protein 0.0025 0.0019 0.0032
Echinococcus granulosus transcription factor Dp 1 0.0041 0.0069 0.0106
Giardia lamblia Alpha-tubulin 0.0902 0.2816 0.77
Giardia lamblia Aldose reductase 0.0253 0.0747 0.2027
Trichomonas vaginalis phosphofructokinase, putative 0.0029 0.0032 0.0074
Trichomonas vaginalis aldo-keto reductase, putative 0.0073 0.0174 0.0464
Loa Loa (eye worm) hypothetical protein 0.0019 0.0001 0.0002
Plasmodium vivax 3-oxoacyl-[acyl-carrier-protein] synthase i/ii, putative 0.025 0.0736 0.201
Schistosoma mansoni thyroid hormone receptor 0.0041 0.007 0.0107
Mycobacterium leprae Probable fatty-acid-CoA synthetase FadD22 (fatty-acid-CoA ligase) (fatty-acid-CoA synthase) 0.0108 0.0284 0.0567
Echinococcus granulosus aldehyde dehydrogenase mitochondrial 0.0131 0.0358 0.0547
Mycobacterium leprae PROBABLE OXIDOREDUCTASE 0.0253 0.0747 0.1561
Loa Loa (eye worm) hypothetical protein 0.0902 0.2816 0.5342
Plasmodium vivax oxidoreductase, aldo/keto reductase domain containing protein 0.0073 0.0174 0.0471
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.0041 0.007 0.0107
Mycobacterium leprae PROBABLE DNA LIGASE [NAD DEPENDENT] LIGA (POLYDEOXYRIBONUCLEOTIDE SYNTHASE [NAD+]) 0.0027 0.0025 0.0013
Schistosoma mansoni hypothetical protein 0.0095 0.0243 0.0371
Trichomonas vaginalis conserved hypothetical protein 0.0073 0.0174 0.0464
Brugia malayi Smad1 0.0024 0.0017 0.0029
Trichomonas vaginalis tubulin beta chain, putative 0.0902 0.2816 0.7702
Mycobacterium ulcerans quinone reductase Qor 0.0062 0.0137 0.0253
Echinococcus granulosus tumor protein p63 0.0339 0.1021 0.1559
Mycobacterium tuberculosis Polyketide synthetase MbtC (polyketide synthase) 0.0342 0.103 0.2169
Loa Loa (eye worm) hypothetical protein 0.0041 0.007 0.0133
Loa Loa (eye worm) hypothetical protein 0.0062 0.0137 0.026
Echinococcus granulosus 3 oxoacyl acyl carrier protein synthase 0.025 0.0736 0.1124
Echinococcus granulosus GA binding protein alpha chain 0.0068 0.0157 0.024
Wolbachia endosymbiont of Brugia malayi exonuclease III 0.0039 0.0064 0.053
Loa Loa (eye worm) hypothetical protein 0.0062 0.0137 0.026
Schistosoma mansoni zinc binding dehydrogenase 0.0062 0.0137 0.0209
Mycobacterium ulcerans cytochrome P450 185A4 Cyp185A4 0.0038 0.0061 0.0091
Leishmania major beta tubulin 0.1165 0.3655 1
Trichomonas vaginalis chromobox protein, putative 0.0071 0.0166 0.0443
Trichomonas vaginalis tubulin beta chain, putative 0.0362 0.1094 0.2986
Trypanosoma cruzi NADP-dependent alcohol hydrogenase, putative 0.0062 0.0137 0.0355
Schistosoma mansoni [ACP] S-malonyltransferase 0.0063 0.014 0.0214
Leishmania major ATP-dependent phosphofructokinase 0.0106 0.0279 0.0744
Onchocerca volvulus Tankyrase homolog 0.0091 0.023 0.0407
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.0041 0.007 0.0107
Brugia malayi hypothetical protein 0.0022 0.0009 0.0014
Echinococcus multilocularis tubulin alpha chain 0.0902 0.2816 0.2816
Schistosoma mansoni loxhd1 0.0019 0.0002 0.0002
Schistosoma mansoni hypothetical protein 0.0095 0.0243 0.0371
Trypanosoma cruzi nuclear receptor binding factor, putative 0.0062 0.0137 0.0355
Entamoeba histolytica ABC transporter, putative 0.0061 0.0135 0.035
Loa Loa (eye worm) hypothetical protein 0.005 0.0098 0.0186
Toxoplasma gondii beta-tubulin, putative 0.1165 0.3655 1
Toxoplasma gondii 6-phosphofructokinase 0.0029 0.0032 0.0066
Leishmania major aldehyde dehydrogenase, mitochondrial precursor 0.0131 0.0358 0.0962
Schistosoma mansoni hypothetical protein 0.0597 0.1843 0.2814
Echinococcus multilocularis ATP dependent DNA helicase Q1 0.0028 0.0029 0.0029
Mycobacterium ulcerans non-ribosomal peptide synthetase 0.0101 0.0264 0.0525
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.0027 0.0026 0.005
Echinococcus granulosus lysine specific demethylase 6a 0.004 0.0069 0.0105
Echinococcus granulosus nibrin 0.0027 0.0025 0.0038
Entamoeba histolytica P-glycoprotein-5 0.0033 0.0044 0.01
Echinococcus multilocularis ATP binding cassette subfamily B (MDR:TAP) 0.0033 0.0044 0.0044
Onchocerca volvulus 0.0115 0.0308 0.0544
Brugia malayi nuclear hormone receptor family member nhr-6 0.0019 0.0001 0.0002
Brugia malayi MH1 domain containing protein 0.0024 0.0017 0.0029
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.0028 0.0029 0.006
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0022 0.0009 0.0013
Trypanosoma cruzi JmjC domain, hydroxylase, putative 0.004 0.0069 0.0168
Echinococcus granulosus NADH dehydrogenase 0.01 0.026 0.0398
Entamoeba histolytica tubulin alpha-1 chain 0.0902 0.2816 0.77
Mycobacterium ulcerans zinc-dependent alcohol dehydrogenase 0.0062 0.0137 0.0253
Trichomonas vaginalis ABC transporter, half transporter, putative 0.0033 0.0044 0.0109
Trypanosoma cruzi hypothetical protein, conserved 0.0027 0.0025 0.0048
Mycobacterium leprae PHENOLPTHIOCEROL SYNTHESIS TYPE-I POLYKETIDE SYNTHASE PPSB 0.08 0.2492 0.5305
Plasmodium falciparum tubulin beta chain 0.1165 0.3655 1
Trichomonas vaginalis tubulin alpha-1 chain, putative 0.054 0.1662 0.454
Trypanosoma brucei protein kinase, putative 0.1068 0.3347 0.9156
Echinococcus multilocularis aldo keto reductase family 1, member B4 0.0253 0.0747 0.0747
Toxoplasma gondii histone lysine demethylase JMJD6a 0.004 0.0069 0.0168
Echinococcus granulosus peregrin 0.0035 0.0052 0.0079
Echinococcus granulosus ecdysone induced protein 78C 0.0041 0.007 0.0107
Trichomonas vaginalis tubulin epsilon chain, putative 0.0278 0.0826 0.225
Mycobacterium ulcerans Zn-dependent alcohol dehydrogenase, AdhX 0.0062 0.0137 0.0253
Trypanosoma brucei tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.007 0.0164 0.0436
Brugia malayi Tnks protein 0.0091 0.023 0.0387
Onchocerca volvulus 0.0253 0.0747 0.132
Echinococcus multilocularis mitochondrial trans 2 enoyl coenzyme A reductase 0.0062 0.0137 0.0137
Echinococcus granulosus tyrosyl DNA phosphodiesterase 1 0.007 0.0164 0.025
Loa Loa (eye worm) hypothetical protein 0.0022 0.0009 0.0016
Plasmodium falciparum conserved Plasmodium protein, unknown function 0.015 0.0419 0.1142
Echinococcus granulosus ATP binding cassette subfamily B MDR:TAP 0.0033 0.0044 0.0067
Schistosoma mansoni aminoadipate-semialdehyde dehydrogenase 0.0091 0.0231 0.0353
Brugia malayi Doublecortin family protein 0.0019 0.0002 0.0003
Trichomonas vaginalis tubulin, putative 0.0362 0.1094 0.2986
Mycobacterium tuberculosis S-nitrosomycothiol reductase MscR 0.0062 0.0137 0.0253
Echinococcus granulosus importin subunit beta 1 0.0056 0.0118 0.018
Trypanosoma brucei inositol-1(or 4)-monophosphatase 1, putative 0.0041 0.0069 0.0178
Loa Loa (eye worm) hypothetical protein 0.0022 0.0009 0.0016
Trypanosoma cruzi DNA polymerase beta thumb, putative 0.0042 0.0072 0.0178
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0019 0.0001 0.0002
Mycobacterium ulcerans 6-phosphofructokinase 0.0106 0.0279 0.0558
Toxoplasma gondii kringle domain-containing protein 0.0022 0.001 0.0008
Loa Loa (eye worm) PHD-finger family protein 0.0038 0.0061 0.0117
Leishmania major aldo-keto reductase-like protein 0.0253 0.0747 0.2027
Mycobacterium tuberculosis Probable oxidoreductase 0.0062 0.0137 0.0253
Loa Loa (eye worm) D-ets-4 DNA binding domain-containing protein 0.0068 0.0157 0.0298
Schistosoma mansoni steroid hormone receptor ad4bp 0.0041 0.007 0.0107
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0041 0.007 0.0117
Loa Loa (eye worm) hypothetical protein 0.0071 0.0166 0.0315
Entamoeba histolytica hypothetical protein 0.0026 0.0022 0.0039
Trypanosoma cruzi DNA polymerase eta, putative 0.0035 0.0052 0.0122
Echinococcus multilocularis Malonyl coenzyme A acyl carrier protein transacylase 0.0063 0.014 0.014
Echinococcus granulosus AMP dependent ligase 0.0101 0.0264 0.0402
Onchocerca volvulus 0.0031 0.0039 0.007
Brugia malayi MH2 domain containing protein 0.0356 0.1076 0.1808
Mycobacterium leprae PHENOLPTHIOCEROL SYNTHESIS TYPE-I POLYKETIDE SYNTHASE PPSE 0.0658 0.2037 0.433
Mycobacterium ulcerans hypothetical protein 0.01 0.026 0.0518
Brugia malayi latrophilin 2 splice variant baaae 0.0205 0.0595 0.1
Echinococcus granulosus lamin 0.0027 0.0026 0.004
Entamoeba histolytica phosphofructokinase, putative 0.0106 0.0279 0.0744
Trichomonas vaginalis multidrug resistance protein 1, 2, putative 0.0033 0.0044 0.0109
Plasmodium vivax tubulin alpha chain, putative 0.0902 0.2816 0.7704
Echinococcus multilocularis tissue type plasminogen activator 0.0022 0.001 0.001
Trypanosoma cruzi DNA polymerase beta thumb, putative 0.0042 0.0072 0.0178
Echinococcus granulosus ATP binding cassette subfamily B MDR:TAP 0.0033 0.0044 0.0067
Echinococcus granulosus tubulin alpha chain 0.0902 0.2816 0.4301
Chlamydia trachomatis DNA ligase 0.0027 0.0025 0.0046
Loa Loa (eye worm) beta-tubulin 0.1165 0.3655 0.6934
Schistosoma mansoni gcn5proteinral control of amino-acid synthesis 5-like 2 gcnl2 0.0136 0.0373 0.0569
Echinococcus multilocularis ATP binding cassette subfamily B (MDR:TAP) 0.0033 0.0044 0.0044
Trichomonas vaginalis multidrug resistance protein 1, 2, putative 0.0033 0.0044 0.0109
Onchocerca volvulus Heterochromatin protein 1 homolog 0.004 0.0067 0.0118
Trypanosoma cruzi ABC transporter, putative 0.0061 0.0135 0.035
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0042 0.0072 0.0178
Entamoeba histolytica NADP-dependent alcohol dehydrogenase, putative 0.0062 0.0137 0.0355
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.0041 0.007 0.0107
Echinococcus multilocularis Tubulin alpha 1 chain 0.0902 0.2816 0.2816
Echinococcus granulosus Tubulin beta 2C chain 0.1165 0.3655 0.5582
Loa Loa (eye worm) hypothetical protein 0.0553 0.1704 0.3232
Entamoeba histolytica hypothetical protein 0.0065 0.0146 0.0379
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.0041 0.007 0.0133
Trichomonas vaginalis importin beta-1, putative 0.0045 0.0084 0.0219
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.0066 0.0152 0.0231
Plasmodium vivax GTP-binding nuclear protein RAN/TC4, putative 0.0021 0.0008 0.0016
Trypanosoma brucei beta tubulin 0.064 0.198 0.5412
Giardia lamblia Pyrophosphate-fructose 6-phosphate 1-phosphotransferase alpha subunit 0.0029 0.0032 0.0066
Echinococcus granulosus multidrug resistance protein 1 0.0023 0.0013 0.002
Schistosoma mansoni tubulin subunit alpha 0.0902 0.2816 0.4301
Trichomonas vaginalis conserved hypothetical protein 0.0027 0.0025 0.0057
Brugia malayi Intermediate filament tail domain containing protein 0.0027 0.0026 0.0044
Schistosoma mansoni transcription factor LCR-F1 0.0073 0.0174 0.0266
Trypanosoma brucei mitochondrial DNA polymerase beta-PAK 0.014 0.0386 0.1044
Loa Loa (eye worm) cytochrome P450 family protein 0.0038 0.0061 0.0117
Echinococcus multilocularis aldo keto reductase family 1, member B4 0.0253 0.0747 0.0747
Onchocerca volvulus 0.0091 0.0231 0.0409
Plasmodium falciparum ADP-dependent DNA helicase RecQ 0.0038 0.006 0.0161
Brugia malayi hypothetical protein 0.0296 0.0882 0.1483
Trichomonas vaginalis aldo-keto reductase, putative 0.0253 0.0747 0.2034
Brugia malayi Latrophilin receptor protein 2 0.0095 0.0243 0.0409
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.003 0.0036 0.0087
Trichomonas vaginalis tubulin alpha-1 chain, putative 0.0362 0.1094 0.2986
Toxoplasma gondii tubulin/FtsZ family, GTPase domain-containing protein 0.0278 0.0826 0.2244
Trichomonas vaginalis tubulin alpha chain, putative 0.064 0.198 0.5413
Toxoplasma gondii inositol(myo)-1(or 4)-monophosphatase 2, putative 0.0041 0.0069 0.017
Echinococcus multilocularis nuclear receptor nhr 48 0.0019 0.0001 0.0001
Onchocerca volvulus Protein ultraspiracle homolog 0.0041 0.007 0.0124
Onchocerca volvulus DNA ligase 3 homolog 0.0058 0.0126 0.0222
Giardia lamblia Epsilon tubulin 0.0278 0.0826 0.2244
Mycobacterium ulcerans aldehyde dehydrogenase 0.0131 0.0358 0.0728
Mycobacterium ulcerans short-chain dehydrogenase 0.0069 0.0161 0.0305
Loa Loa (eye worm) hypothetical protein 0.0022 0.0009 0.0016
Loa Loa (eye worm) BEN-1 protein 0.1165 0.3655 0.6934
Toxoplasma gondii tubulin/FtsZ family, GTPase domain-containing protein 0.0278 0.0826 0.2244
Entamoeba histolytica hypothetical protein 0.0091 0.023 0.0611
Loa Loa (eye worm) latrophilin receptor protein 2 0.0095 0.0243 0.0461
Entamoeba histolytica hypothetical protein 0.0073 0.0174 0.0457
Brugia malayi Calcitonin receptor-like protein seb-1 0.03 0.0898 0.1509
Trichomonas vaginalis ap endonuclease, putative 0.0039 0.0064 0.0165
Echinococcus multilocularis Tubulin beta 2C chain 0.1165 0.3655 0.3655
Mycobacterium tuberculosis Probable polyketide synthase Pks8 0.0813 0.2534 0.5395
Plasmodium vivax ataxin-2 like protein, putative 0.0025 0.0018 0.0045
Trypanosoma brucei acyl transferase-like protein 0.0063 0.014 0.0372
Trichomonas vaginalis dihydrodiol dehydrogenase, putative 0.0253 0.0747 0.2034
Schistosoma mansoni retinoic acid receptor RXR 0.0041 0.007 0.0107
Schistosoma mansoni alpha tubulin 0.0902 0.2816 0.4301
Giardia lamblia Delta tubulin 0.0278 0.0826 0.2244
Toxoplasma gondii acyl transferase domain-containing protein 0.0063 0.014 0.0364
Leishmania major isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0032 0.004 0.009
Onchocerca volvulus Fatty acid synthase homolog 0.1793 0.5657 1
Brugia malayi Tubulin alpha-2 chain 0.0902 0.2816 0.4732
Toxoplasma gondii histone lysine acetyltransferase GCN5-B 0.0043 0.0077 0.0191
Mycobacterium tuberculosis Probable quinone reductase Qor (NADPH:quinone reductase) (zeta-crystallin homolog protein) 0.0062 0.0137 0.0253
Plasmodium vivax AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0039 0.0064 0.0172
Echinococcus multilocularis multidrug resistance protein 1 0.0033 0.0044 0.0044
Schistosoma mansoni nuclear receptor nhr-48 0.0019 0.0001 0.0002
Trypanosoma cruzi DNA polymerase eta, putative 0.0058 0.0125 0.0321
Loa Loa (eye worm) hypothetical protein 0.004 0.0069 0.013
Brugia malayi hypothetical protein 0.0027 0.0025 0.0042
Schistosoma mansoni ap endonuclease 0.0039 0.0064 0.0098
Trypanosoma cruzi epsilon tubulin, putative 0.064 0.198 0.5409
Wolbachia endosymbiont of Brugia malayi acyl carrier protein 0.01 0.026 0.2966
Toxoplasma gondii aldo-keto reductase 0.0073 0.0174 0.0456
Echinococcus multilocularis multidrug resistance protein 1 0.0023 0.0013 0.0013
Leishmania major alpha tubulin 0.0902 0.2816 0.77
Loa Loa (eye worm) TK/ROR protein kinase 0.0022 0.001 0.002
Trichomonas vaginalis multidrug resistance protein 1, 2, putative 0.0033 0.0044 0.0109
Echinococcus granulosus beta tubulin 0.1165 0.3655 0.5582
Echinococcus granulosus Tubulin alpha 1 chain 0.0902 0.2816 0.4301
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0041 0.007 0.0117
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.003 0.0036 0.0087
Echinococcus multilocularis tubulin alpha 1C chain 0.0902 0.2816 0.2816
Brugia malayi Cytochrome P450 family protein 0.0038 0.0061 0.0103
Mycobacterium ulcerans glutaminase 0.0273 0.081 0.1697
Trichomonas vaginalis tubulin alpha chain, putative 0.0362 0.1094 0.2986
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0095 0.0243 0.0371
Mycobacterium tuberculosis P-hydroxybenzoyl-AMP ligase FadD22 0.0108 0.0284 0.0567
Entamoeba histolytica myo-inositol monophosphatase, putative 0.0041 0.0069 0.017
Echinococcus multilocularis GA binding protein alpha chain 0.0068 0.0157 0.0157
Echinococcus multilocularis PHD finger protein rhinoceros 0.0027 0.0027 0.0027
Brugia malayi RNA, U transporter 1 0.0159 0.0447 0.0751
Mycobacterium tuberculosis Probable NADPH quinone oxidoreductase FadB4 (NADPH:quinone reductase) (zeta-crystallin) 0.0062 0.0137 0.0253
Schistosoma mansoni importin beta-1 0.0056 0.0118 0.018
Plasmodium vivax replication factor C subunit 1, putative 0.0027 0.0025 0.0065
Leishmania major alpha tubulin 0.0902 0.2816 0.77
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.0041 0.007 0.0107
Echinococcus multilocularis Tubulin alpha 1 chain 0.0902 0.2816 0.2816
Mycobacterium tuberculosis Peptide synthetase MbtF (peptide synthase) 0.0108 0.0284 0.0567
Brugia malayi nuclear receptor RXR 0.0022 0.0009 0.0014
Echinococcus granulosus aldo keto reductase family 1 member B4 0.0253 0.0747 0.114
Plasmodium falciparum alpha tubulin 2 0.0902 0.2816 0.7704
Echinococcus granulosus inositol monophosphatase 1 0.0041 0.0069 0.0106
Loa Loa (eye worm) BEN-1 protein 0.1165 0.3655 0.6934
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.0039 0.0064 0.0122
Trypanosoma brucei DNA polymerase kappa, putative 0.0059 0.0128 0.0339
Schistosoma mansoni acyl carrier protein 0.01 0.026 0.0398
Toxoplasma gondii histone lysine acetyltransferase GCN5-A 0.0043 0.0077 0.0191
Brugia malayi Tyrosyl-DNA phosphodiesterase family protein 0.007 0.0164 0.0275
Trypanosoma brucei DNA polymerase kappa, putative 0.0036 0.0056 0.014
Leishmania major tyrosyl-DNA phosphodiesterase 1 0.007 0.0164 0.0428
Schistosoma mansoni NADP-specific isocitrate dehydrogenase 0.0032 0.004 0.0062
Echinococcus granulosus aldo keto reductase family 1, member B4 0.0073 0.0174 0.0265
Loa Loa (eye worm) hypothetical protein 0.0027 0.0025 0.0047
Trypanosoma cruzi aldo-keto reductase 0.0253 0.0747 0.2027
Echinococcus multilocularis AMP dependent ligase 0.0101 0.0264 0.0264
Trichomonas vaginalis ABC transporter, putative 0.0033 0.0044 0.0109
Trichomonas vaginalis aldo-keto reductase, putative 0.0253 0.0747 0.2034
Entamoeba histolytica P-glycoprotein-2, putative 0.0033 0.0044 0.01
Leishmania major p-glycoprotein 0.0033 0.0044 0.01
Trypanosoma brucei unspecified product 0.0023 0.0013 0.0022
Schistosoma mansoni rab6-interacting 0.0019 0.0002 0.0002
Giardia lamblia Sgs1 DNA helicase, putative 0.0028 0.0029 0.006
Onchocerca volvulus 0.0253 0.0747 0.132
Mycobacterium ulcerans thioesterase TesA 0.0829 0.2583 0.55
Toxoplasma gondii phosphofructokinase domain-containing protein 0.0029 0.0032 0.0066
Echinococcus multilocularis gcn5proteinral control of amino acid synthesis 0.0136 0.0373 0.0373
Trypanosoma brucei DNA polymerase beta thumb, putative 0.0042 0.0072 0.0186
Brugia malayi ecdysteroid receptor 0.0041 0.007 0.0117
Echinococcus granulosus tubulin alpha chain 0.0902 0.2816 0.4301
Schistosoma mansoni hypothetical protein 0.0022 0.001 0.0016
Treponema pallidum diphosphate--fructose-6-phosphate 1-phosphotransferase 0.0029 0.0032 0.012
Schistosoma mansoni alcohol dehydrogenase 0.0062 0.0137 0.0209
Mycobacterium leprae Probable S-nitrosomycothiol reductase MscR 0.0062 0.0137 0.0253
Trichomonas vaginalis aldo-keto reductase, putative 0.0253 0.0747 0.2034
Echinococcus multilocularis dna polymerase kappa 0.0059 0.0128 0.0128
Trypanosoma cruzi mitogen activated protein kinase 4, putative 0.1068 0.3347 0.9155
Mycobacterium tuberculosis Probable isocitrate dehydrogenase [NADP] Icd1 (oxalosuccinate decarboxylase) (IDH) (NADP+-specific ICDH) (IDP) 0.0032 0.004 0.0046
Leishmania major mitochondrial DNA polymerase beta 0.0295 0.0882 0.2397
Schistosoma mansoni lamin 0.0027 0.0026 0.004
Schistosoma mansoni hypothetical protein 0.0107 0.028 0.0428
Plasmodium falciparum holo-[acyl-carrier-protein] synthase, putative 0.0026 0.0022 0.0056
Onchocerca volvulus 0.0019 0.0001 0.0002
Mycobacterium ulcerans transmembrane ABC transporter ATP-binding protein 0.0061 0.0135 0.0249
Mycobacterium ulcerans NADP-dependent alcohol dehydrogenase Adh 0.0062 0.0137 0.0253
Trichomonas vaginalis dihydrodiol dehydrogenase, putative 0.0253 0.0747 0.2034
Loa Loa (eye worm) AMP-binding enzyme family protein 0.0937 0.2926 0.5552
Plasmodium falciparum tubulin epsilon chain, putative 0.064 0.198 0.5416
Trypanosoma cruzi acyl transferase-like protein, putative 0.0063 0.014 0.0364
Echinococcus multilocularis mitogen activated protein kinase 0.1068 0.3347 0.3347
Echinococcus granulosus TGF beta signal transducer SmadC 0.0024 0.0017 0.0027
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.0041 0.007 0.0133
Echinococcus multilocularis Polycystic kidney disease protein 0.0019 0.0002 0.0002
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.0118 0.0317 0.0483
Leishmania major acyl carrier protein, putative 0.01 0.026 0.0693
Echinococcus multilocularis voltage gated potassium channel subunit 0.0073 0.0174 0.0174
Loa Loa (eye worm) hypothetical protein 0.0033 0.0044 0.0083
Brugia malayi Pre-SET motif family protein 0.023 0.0675 0.1134
Trypanosoma cruzi ATP-dependent DEAD/H DNA helicase recQ, putative 0.0031 0.0037 0.0082
Trichomonas vaginalis conserved hypothetical protein 0.0027 0.0025 0.0057
Echinococcus granulosus microtubule associated protein 2 0.2072 0.6548 1
Toxoplasma gondii Zn-containing alcohol dehydrogenase 0.0062 0.0137 0.0355
Echinococcus granulosus lipoxygenase domain containing protein 0.0019 0.0002 0.0002
Trichomonas vaginalis abcb9, putative 0.0033 0.0044 0.0109
Loa Loa (eye worm) jmjC domain-containing protein 0.0057 0.012 0.0228
Plasmodium vivax histone acetyltransferase GCN5, putative 0.0043 0.0077 0.0207
Loa Loa (eye worm) hypothetical protein 0.012 0.0322 0.0611
Echinococcus granulosus Transcription factor JmjC domain containing protein 0.0208 0.0603 0.0921
Echinococcus granulosus muscleblind protein 0.0305 0.0912 0.1392
Entamoeba histolytica acetyltransferase, GNAT family 0.0035 0.0053 0.0124
Leishmania major importin beta-1 subunit, putative 0.0045 0.0084 0.0211
Mycobacterium ulcerans fatty-acid-CoA ligase FadD9 0.0101 0.0264 0.0525
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0055 0.0116 0.0116
Brugia malayi Tubulin alpha-2 chain 0.0902 0.2816 0.4732
Loa Loa (eye worm) hypothetical protein 0.0041 0.007 0.0133
Trypanosoma brucei DNA polymerase kappa, putative 0.0029 0.0033 0.0079
Trichomonas vaginalis lipid A export ATP-binding/permease protein msba, putative 0.0033 0.0044 0.0109
Trypanosoma cruzi PAB1-binding protein , putative 0.0025 0.0018 0.0029
Schistosoma mansoni tubulin subunit delta 0.0278 0.0826 0.1261
Mycobacterium tuberculosis Conserved hypothetical protein 0.0033 0.0045 0.0056
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.003 0.0036 0.0087
Loa Loa (eye worm) tubulin beta-1 chain 0.1165 0.3655 0.6934
Leishmania major 4-coumarate:coa ligase-like protein 0.0025 0.0019 0.0032
Echinococcus granulosus aldo keto reductase 0.0253 0.0747 0.114
Mycobacterium tuberculosis Probable polyketide synthase Pks1 0.0715 0.2218 0.4718
Trypanosoma brucei JmjC domain, hydroxylase, putative 0.004 0.0069 0.0176
Schistosoma mansoni tubulin subunit gamma 0.064 0.198 0.3024
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.0041 0.007 0.0133
Plasmodium vivax SET domain protein, putative 0.0035 0.005 0.0133
Schistosoma mansoni zinc finger protein 0.0028 0.003 0.0046
Echinococcus multilocularis geminin 0.0504 0.1546 0.1546
Trichomonas vaginalis DNA polymerase IV / kappa, putative 0.0059 0.0128 0.0339
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0032 0.004 0.004
Trichomonas vaginalis 6-phosphofructokinase, putative 0.0029 0.0032 0.0074
Echinococcus multilocularis beta tubulin 0.1165 0.3655 0.3655
Plasmodium vivax delta tubulin, putative 0.0278 0.0826 0.2256
Brugia malayi Nuclear hormone receptor-like 1 0.0041 0.007 0.0117
Schistosoma mansoni cpg binding protein 0.009 0.0227 0.0346
Mycobacterium ulcerans phenolpthiocerol synthesis type-I polyketide synthase PpsB 0.08 0.2492 0.5305
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.1068 0.3347 0.9155
Echinococcus granulosus snurportin 1 0.0597 0.1843 0.2814
Echinococcus multilocularis ecdysone induced protein 78C 0.0041 0.007 0.007
Echinococcus granulosus GPCR family 2 0.0095 0.0243 0.0371
Toxoplasma gondii aldehyde dehydrogenase 0.0131 0.0358 0.0962
Entamoeba histolytica P-glycoprotein-2 0.0033 0.0044 0.01
Trypanosoma brucei oxidoreductase, putative 0.0062 0.0137 0.0363
Mycobacterium leprae Probable alcohol dehydrogenase AdhA 0.0062 0.0137 0.0253
Trichomonas vaginalis tubulin gamma chain, putative 0.0278 0.0826 0.225
Trypanosoma cruzi Acyl carrier protein, mitochondrial, putative 0.01 0.026 0.0693
Trypanosoma cruzi hypothetical protein, conserved 0.0027 0.0025 0.0048
Brugia malayi oxidoreductase, aldo/keto reductase family protein 0.0253 0.0747 0.1255
Brugia malayi Ets-domain containing protein 0.0068 0.0157 0.0264
Echinococcus multilocularis aldo keto reductase 0.0253 0.0747 0.0747
Leishmania major DNA polymerase kappa, putative,DNA polymerase IV, putative 0.0039 0.0066 0.016
Mycobacterium ulcerans quinone oxidoreductase 0.0062 0.0137 0.0253
Leishmania major beta tubulin 0.1165 0.3655 1
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0055 0.0116 0.0177
Leishmania major mitogen activated protein kinase 4, putative;with=GeneDB:LmxM19.1440 0.1068 0.3347 0.9155
Toxoplasma gondii isocitrate dehydrogenase 0.0032 0.004 0.009
Trypanosoma brucei alpha tubulin 0.0902 0.2816 0.7702
Plasmodium vivax importin-beta 2, putative 0.0056 0.0118 0.0319
Toxoplasma gondii 4'-phosphopantetheinyl transferase domain-containing protein 0.0026 0.0022 0.0039
Trichomonas vaginalis DNA polymerase eta, putative 0.0059 0.0128 0.0339
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD9 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0101 0.0264 0.0525
Brugia malayi beta-NAC-like protein 0.0065 0.0146 0.0245
Loa Loa (eye worm) hypothetical protein 0.0028 0.0029 0.0055
Trichomonas vaginalis aldo-keto reductase, putative 0.0253 0.0747 0.2034
Trypanosoma cruzi zeta tubulin, putative 0.0278 0.0826 0.2244
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0055 0.0116 0.022
Trichomonas vaginalis conserved hypothetical protein 0.0091 0.023 0.0619
Plasmodium falciparum acyl carrier protein 0.01 0.026 0.0708
Brugia malayi ATP-dependent DNA helicase, RecQ family protein 0.0028 0.0029 0.0049
Trichomonas vaginalis tubulin, putative 0.0278 0.0826 0.225
Loa Loa (eye worm) hypothetical protein 0.0624 0.193 0.3662
Schistosoma mansoni ABC transporter 0.0052 0.0106 0.0161
Plasmodium vivax holo-[acyl-carrier-protein] synthase, putative 0.0026 0.0022 0.0056
Echinococcus granulosus alpha tubulin 0.0902 0.2816 0.4301
Echinococcus multilocularis 3 oxoacyl (acyl carrier protein) synthase 0.025 0.0736 0.0736
Schistosoma mansoni tubulin subunit alpha 0.0278 0.0826 0.1261
Mycobacterium leprae possible inositol monophosphatase SubH (IMPase) (inositol-1-phosphatase) (I-1-Pase ). 0.0036 0.0056 0.0079
Trypanosoma cruzi DNA polymerase kappa, putative 0.0059 0.0128 0.0331
Leishmania major DNA polymerase kappa, putative 0.0039 0.0066 0.016
Trypanosoma brucei ABC transporter, putative 0.0061 0.0135 0.0358
Leishmania major ferric reductase, putative 0.0034 0.0049 0.0114
Schistosoma mansoni 6-phosphofructokinase 0.0106 0.0279 0.0426
Echinococcus granulosus Tubulin alpha 1 chain 0.0902 0.2816 0.4301
Trichomonas vaginalis chromobox protein, putative 0.0043 0.0076 0.0197
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.1068 0.3347 0.9155
Loa Loa (eye worm) transcription factor SMAD2 0.0356 0.1076 0.2041
Loa Loa (eye worm) hypothetical protein 0.054 0.1662 0.3152
Giardia lamblia Alpha-tubulin 0.0902 0.2816 0.77
Mycobacterium tuberculosis Phenolpthiocerol synthesis type-I polyketide synthase PpsA 0.0995 0.3111 0.6635
Trichomonas vaginalis tubulin beta chain, putative 0.0902 0.2816 0.7702
Plasmodium vivax ABC transporter G family member 2, putative 0.0061 0.0135 0.0365
Echinococcus granulosus histone acetyltransferase KAT2B 0.0043 0.0077 0.0118
Echinococcus granulosus cpg binding protein 0.009 0.0227 0.0346
Echinococcus multilocularis ATP binding cassette sub family G 0.0061 0.0135 0.0135
Plasmodium falciparum tubulin delta chain, putative 0.0278 0.0826 0.2256
Schistosoma mansoni hypothetical protein 0.0028 0.003 0.0046
Mycobacterium tuberculosis Phenolpthiocerol synthesis type-I polyketide synthase PpsE 0.0153 0.0426 0.0874
Echinococcus multilocularis tubulin subunit TubB 0.0902 0.2816 0.2816
Loa Loa (eye worm) oxidoreductase 0.0253 0.0747 0.1417
Echinococcus granulosus beta tubulin 0.1165 0.3655 0.5582
Trichomonas vaginalis tubulin alpha-1 chain, putative 0.0624 0.193 0.5275
Loa Loa (eye worm) ImpB/MucB/SamB family protein 0.0033 0.0045 0.0086
Echinococcus multilocularis aldo keto reductase family 1, member B4 0.0253 0.0747 0.0747
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.0041 0.007 0.0107
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0032 0.0041 0.0062
Echinococcus granulosus aldo keto reductase family 1 member B4 0.0253 0.0747 0.114
Loa Loa (eye worm) hypothetical protein 0.0461 0.141 0.2676
Loa Loa (eye worm) alcohol dehydrogenase class III 0.0062 0.0137 0.026
Mycobacterium tuberculosis Hypothetical protein 0.03 0.0895 0.188
Trypanosoma cruzi apurinic/apyrimidinic endonuclease 0.0039 0.0064 0.0156
Mycobacterium tuberculosis Possible oxidoreductase FadB5 0.0062 0.0137 0.0253
Onchocerca volvulus 0.0062 0.0137 0.0242
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.0041 0.007 0.007
Echinococcus granulosus hypothetical protein 0.0253 0.0747 0.114
Trypanosoma brucei importin beta-1 subunit, putative 0.0056 0.0118 0.0311
Loa Loa (eye worm) 6-phosphofructokinase 0.0106 0.0279 0.0529
Brugia malayi hypothetical protein 0.012 0.0322 0.0541
Echinococcus multilocularis lamin 0.0027 0.0026 0.0026
Trichomonas vaginalis aldo-keto reductase, putative 0.0253 0.0747 0.2034
Plasmodium vivax acyl carrier protein, putative 0.01 0.026 0.0708
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.023 0.0675 0.128
Entamoeba histolytica aldose reductase, putative 0.0253 0.0747 0.2027
Echinococcus granulosus voltage gated potassium channel subunit 0.0073 0.0174 0.0265
Echinococcus multilocularis tubulin alpha 1C chain 0.0902 0.2816 0.2816
Loa Loa (eye worm) hypothetical protein 0.0019 0.0001 0.0002
Brugia malayi AMP-binding enzyme family protein 0.0025 0.0019 0.0032
Trichomonas vaginalis tubulin alpha-1 chain, putative 0.0902 0.2816 0.7702
Echinococcus multilocularis tubulin alpha chain 0.0902 0.2816 0.2816
Brugia malayi MH2 domain containing protein 0.0024 0.0017 0.0029
Echinococcus multilocularis dna polymerase eta 0.0058 0.0125 0.0125
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0019 0.0001 0.0001
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.0041 0.007 0.0133
Schistosoma mansoni rab6-interacting 0.0019 0.0002 0.0002
Echinococcus multilocularis tubulin alpha 3 chain 0.0902 0.2816 0.2816
Schistosoma mansoni topbp1 0.0027 0.0025 0.0038
Echinococcus multilocularis multidrug resistance protein 1 0.0033 0.0044 0.0044
Echinococcus multilocularis aldo keto reductase family 1, member B4 0.0253 0.0747 0.0747
Brugia malayi steroid hormone receptor 0.0041 0.007 0.0117
Trypanosoma cruzi oxidoreductase, putative 0.0062 0.0137 0.0355
Loa Loa (eye worm) acyl carrier protein 0.0457 0.1398 0.2653
Echinococcus multilocularis ATP binding cassette subfamily B (MDR:TAP) 0.0033 0.0044 0.0044
Brugia malayi phosphofructokinase 0.0106 0.0279 0.0469
Brugia malayi nuclear receptor NHR-88 0.0019 0.0001 0.0002
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.0041 0.007 0.0133
Echinococcus granulosus smad 0.0024 0.0017 0.0027
Loa Loa (eye worm) RecQ helicase 0.004 0.0068 0.013
Schistosoma mansoni nuclear hormone receptor superfamily protein-related 0.0019 0.0001 0.0002
Schistosoma mansoni aldehyde dehydrogenase 0.0131 0.0358 0.0547
Entamoeba histolytica P-glycoprotein 5, putative 0.0033 0.0044 0.01
Echinococcus multilocularis Smad4 0.0024 0.0017 0.0017
Brugia malayi Nuclear hormone receptor family member nhr-49 0.0041 0.007 0.0117
Echinococcus multilocularis lipoxygenase domain containing protein 0.0019 0.0002 0.0002
Loa Loa (eye worm) hypothetical protein 0.0305 0.0912 0.173
Schistosoma mansoni poly [ADP-ribose] polymerase 0.0553 0.1704 0.2602
Mycobacterium ulcerans phosphopantetheinyl transferase, PptII 0.0026 0.0022 0.0006
Mycobacterium ulcerans NAD-dependent DNA ligase LigA 0.0027 0.0025 0.0013
Echinococcus granulosus poly ADP ribose polymerase 1 0.0754 0.2345 0.3581
Trichomonas vaginalis ATP-binding cassette transporter, putative 0.0033 0.0044 0.0109
Echinococcus granulosus ATP binding cassette sub family G 0.0061 0.0135 0.0206
Echinococcus granulosus mitochondrial trans 2 enoyl coenzyme A reductase 0.0062 0.0137 0.0209
Loa Loa (eye worm) PHD-finger family protein 0.0027 0.0027 0.0052
Echinococcus multilocularis aldo keto reductase family 1, member B4 0.0253 0.0747 0.0747
Brugia malayi CHD4 protein 0.002 0.0003 0.0005
Giardia lamblia PHD finger protein 15 0.0027 0.0027 0.0054
Echinococcus granulosus multidrug resistance protein 1 0.0023 0.0013 0.002
Plasmodium vivax aldehyde reductase, putative 0.0073 0.0174 0.0471
Entamoeba histolytica tubulin alpha chain, putative 0.0902 0.2816 0.77
Echinococcus multilocularis tubulin delta chain 0.0278 0.0826 0.0826
Trichomonas vaginalis tubulin beta-1 chain, putative 0.0278 0.0826 0.225
Echinococcus multilocularis ATP binding cassette subfamily B (MDR:TAP) 0.0033 0.0044 0.0044
Trypanosoma cruzi zeta tubulin, putative 0.0278 0.0826 0.2244
Toxoplasma gondii NAC domain-containing protein 0.0065 0.0146 0.0379
Onchocerca volvulus Rap guanine nucleotide exchange factor 1 homolog 0.0198 0.0572 0.1012
Schistosoma mansoni terminal deoxycytidyl transferase 0.0033 0.0045 0.0069
Trichomonas vaginalis chromobox protein, putative 0.0043 0.0076 0.0197
Plasmodium falciparum aldo-keto reductase, putative 0.0073 0.0174 0.0471
Trichomonas vaginalis conserved hypothetical protein 0.0027 0.0025 0.0057
Mycobacterium tuberculosis Probable polyketide synthase Pks9 0.0565 0.1743 0.3699
Loa Loa (eye worm) hypothetical protein 0.0205 0.0595 0.1129
Brugia malayi oxidoreductase, aldo/keto reductase family protein 0.0253 0.0747 0.1255
Loa Loa (eye worm) acetyltransferase 0.0136 0.0373 0.0707
Trypanosoma brucei DNA polymerase eta, putative 0.0058 0.0125 0.0329
Schistosoma mansoni [ACP] S-malonyltransferase 0.0063 0.014 0.0214
Schistosoma mansoni DNA polymerase eta 0.0058 0.0125 0.019
Onchocerca volvulus 0.0025 0.0019 0.0034
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0051 0.0101 0.0257
Trypanosoma brucei alpha tubulin, putative 0.0362 0.1094 0.2986
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.0041 0.007 0.007
Trypanosoma brucei hypothetical protein, conserved 0.0026 0.0022 0.0048
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.0041 0.007 0.0124
Leishmania major beta-ketoacyl synthase family protein, putative,3-oxoacyl-acyl carrier protein synthase ii, putative 0.025 0.0736 0.1997
Trypanosoma brucei Poly(ADP-ribose) polymerase and DNA-Ligase Zn-finger region/Zinc-finger (CX5CX6HX5H) motif containing protein, putative 0.0058 0.0126 0.0332
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0045 0.0084 0.0219
Trichomonas vaginalis conserved hypothetical protein 0.0027 0.0025 0.0057
Brugia malayi Nuclear hormone receptor family member nhr-40 0.0041 0.007 0.0117
Plasmodium falciparum aldehyde reductase, putative 0.0073 0.0174 0.0471
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0095 0.0243 0.0243
Echinococcus multilocularis ATP binding cassette sub family B 0.0032 0.0041 0.0041
Trypanosoma cruzi ISWI complex protein 0.0028 0.003 0.0062
Loa Loa (eye worm) hypothetical protein 0.0027 0.0027 0.0052
Schistosoma mansoni ecdysone-induced protein 78c (dr-78) 0.0022 0.0009 0.0013
Entamoeba histolytica acyl-CoA synthetase, putative 0.0101 0.0264 0.0702
Echinococcus multilocularis microtubule associated protein 2 0.2072 0.6548 0.6548
Onchocerca volvulus 0.0253 0.0747 0.132
Trichomonas vaginalis phosphofructokinase, putative 0.0029 0.0032 0.0074
Schistosoma mansoni poly [ADP-ribose] polymerase 0.0754 0.2345 0.3581
Loa Loa (eye worm) hypothetical protein 0.0019 0.0001 0.0002
Echinococcus granulosus Tubulin beta 2C chain 0.1165 0.3655 0.5582
Schistosoma mansoni chromosome transmission fidelity factor 0.0027 0.0025 0.0038
Echinococcus multilocularis transcription factor Dp 1 0.0041 0.0069 0.0069
Echinococcus multilocularis nuclear receptor subfamily 4 group A 0.0019 0.0001 0.0001
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0055 0.0116 0.0177
Trichomonas vaginalis tubulin epsilon chain, putative 0.0902 0.2816 0.7702
Echinococcus granulosus methyl CpG binding domain protein 2 0.0031 0.004 0.0062
Trypanosoma cruzi Poly(ADP-ribose) polymerase and DNA-Ligase Zn-finger region/Zinc-finger (CX5CX6HX5H) motif containing protein, putative 0.0058 0.0126 0.0324
Onchocerca volvulus Bile acid receptor homolog 0.0041 0.007 0.0124
Schistosoma mansoni glutaminase 0.0273 0.081 0.1237
Schistosoma mansoni TGF-beta signal transducer Smad2 0.0024 0.0017 0.0027
Chlamydia trachomatis acyl carrier protein 0.01 0.026 0.3339
Brugia malayi 6-phosphofructokinase 0.0106 0.0279 0.0469
Plasmodium falciparum ABC transporter G family member 2 0.0061 0.0135 0.0365
Mycobacterium tuberculosis Polyketide synthase Pks13 0.1487 0.468 1
Echinococcus multilocularis mitogen activated protein kinase 3 0.1068 0.3347 0.3347
Mycobacterium ulcerans dehydrogenase 0.0062 0.0137 0.0253
Mycobacterium ulcerans acyl carrier protein 0.01 0.026 0.0518
Brugia malayi Beta-ketoacyl synthase, N-terminal domain containing protein 0.0995 0.3111 0.5228
Echinococcus granulosus tubulin subunit beta 0.1165 0.3655 0.5582
Trypanosoma cruzi DNA polymerase kappa, putative 0.0059 0.0128 0.0331
Loa Loa (eye worm) CHromoDomain protein family member 0.002 0.0003 0.0006
Trichomonas vaginalis tubulin beta chain, putative 0.0902 0.2816 0.7702
Trichomonas vaginalis ATP-binding cassette transporter, putative 0.0033 0.0044 0.0109
Echinococcus granulosus Tubulin beta 2C chain 0.1165 0.3655 0.5582
Leishmania major beta tubulin 0.1165 0.3655 1
Trypanosoma brucei Trans-2-enoyl-ACP reductase 2, putative 0.0062 0.0137 0.0363
Mycobacterium ulcerans acyl-CoA synthetase 0.0108 0.0284 0.0567
Echinococcus multilocularis Tubulin beta 2C chain 0.1165 0.3655 0.3655
Trichomonas vaginalis tubulin epsilon chain, putative 0.1165 0.3655 1
Mycobacterium ulcerans transmembrane ABC transporter ATP-binding protein 0.0061 0.0135 0.0249
Brugia malayi Methyltransferase-like protein 4 0.03 0.0895 0.1504
Trichomonas vaginalis conserved hypothetical protein 0.004 0.0067 0.0171
Schistosoma mansoni tubulin subunit beta 0.1165 0.3655 0.5582
Treponema pallidum acyl carrier protein 0.01 0.026 0.2966
Loa Loa (eye worm) hypothetical protein 0.0025 0.0018 0.0034
Trichomonas vaginalis tubulin, putative 0.0362 0.1094 0.2986
Echinococcus multilocularis fetal alzheimer antigen, falz 0.0046 0.0088 0.0088
Echinococcus granulosus arachidonate 5 lipoxygenase 0.0116 0.0308 0.0471
Trichomonas vaginalis phosphofructokinase, putative 0.0029 0.0032 0.0074
Echinococcus granulosus FTZ F1 alpha 0.0041 0.007 0.0107
Echinococcus granulosus tubulin beta 1 chain 0.1165 0.3655 0.5582
Loa Loa (eye worm) tubulin alpha 2 0.0624 0.193 0.3662
Schistosoma mansoni jumonji/arid domain-containing protein 0.016 0.0449 0.0685
Leishmania major delta tubulin, putative 0.0278 0.0826 0.2244
Echinococcus granulosus ATP dependent DNA helicase Q5 0.0028 0.0029 0.0045
Plasmodium falciparum ataxin-2 like protein, putative 0.0025 0.0018 0.0045
Trypanosoma cruzi alpha tubulin, putative 0.0902 0.2816 0.77
Trichomonas vaginalis taga, putative 0.0033 0.0044 0.0109
Mycobacterium ulcerans fatty acid synthase Fas 0.0312 0.0936 0.1968
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative 0.0039 0.0064 0.0164
Echinococcus multilocularis jumonji domain containing protein 0.0038 0.0062 0.0062
Echinococcus granulosus Polycystic kidney disease protein 0.0019 0.0002 0.0002
Trypanosoma brucei DNA polymerase kappa, putative 0.0059 0.0128 0.0339
Mycobacterium ulcerans zinc-dependent alcohol dehydrogenase AdhE2 0.0062 0.0137 0.0253
Echinococcus granulosus tubulin beta 4A class IVa 0.1165 0.3655 0.5582
Trichomonas vaginalis phosphofructokinase, putative 0.0106 0.0279 0.0752
Loa Loa (eye worm) fli-1 protein 0.0207 0.0599 0.1137
Mycobacterium ulcerans polyketide synthase Pks13 0.1487 0.468 1
Giardia lamblia DINP protein human, muc B family 0.0039 0.0066 0.016
Mycobacterium ulcerans cell division protein FtsZ 0.0278 0.0826 0.1731
Loa Loa (eye worm) hypothetical protein 0.0022 0.0009 0.0016
Trypanosoma brucei zeta tubulin, putative 0.0278 0.0826 0.225
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0073 0.0174 0.0174
Loa Loa (eye worm) hypothetical protein 0.0253 0.0747 0.1417
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0073 0.0174 0.0266
Leishmania major beta tubulin 0.1165 0.3655 1
Trypanosoma brucei isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0032 0.004 0.0098
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0055 0.0116 0.0177
Schistosoma mansoni transcription factor btf3 0.0065 0.0146 0.0223
Echinococcus multilocularis TGF beta signal transducer SmadC 0.0024 0.0017 0.0017
Mycobacterium ulcerans phenolpthiocerol synthesis type-I polyketide synthase PpsE 0.0658 0.2037 0.433
Echinococcus granulosus peroxisome assembly protein 26 0.0902 0.2816 0.4301
Trypanosoma cruzi NADP-dependent alcohol hydrogenase, putative 0.0062 0.0137 0.0355
Loa Loa (eye worm) ABC transporter 0.0052 0.0106 0.02
Brugia malayi hypothetical protein 0.0019 0.0001 0.0002
Brugia malayi Inositol-1 0.0041 0.0069 0.0117
Brugia malayi hypothetical protein 0.0019 0.0002 0.0003
Onchocerca volvulus 0.0262 0.0775 0.1371
Echinococcus multilocularis tubulin gamma 1 chain 0.064 0.198 0.198
Plasmodium falciparum cysteine repeat modular protein 1 0.0022 0.001 0.0024
Echinococcus granulosus ATP binding cassette subfamily B MDR:TAP 0.0033 0.0044 0.0067
Onchocerca volvulus 0.0019 0.0002 0.0003
Trichomonas vaginalis multidrug resistance protein 1, 2, putative 0.0033 0.0044 0.0109
Mycobacterium ulcerans NADP-dependent oxidoreductase 0.0062 0.0137 0.0253
Brugia malayi ImpB/MucB/SamB family protein 0.0058 0.0125 0.021
Trichomonas vaginalis tubulin beta chain, putative 0.1165 0.3655 1
Brugia malayi ATP dependent DNA ligase C terminal region family protein 0.0027 0.0025 0.0042
Trypanosoma brucei tubulin gamma chain 0.064 0.198 0.5412
Mycobacterium ulcerans hypothetical protein 0.0073 0.0174 0.0332
Loa Loa (eye worm) tubulin beta chain 0.0278 0.0826 0.1567
Trypanosoma cruzi DNA repair protein, putative 0.0058 0.0126 0.0324
Loa Loa (eye worm) oxidoreductase 0.0253 0.0747 0.1417
Mycobacterium tuberculosis Meromycolate extension acyl carrier protein AcpM 0.01 0.026 0.0518
Trypanosoma brucei ATP-dependent 6-phosphofructokinase, glycosomal 0.0106 0.0279 0.0752
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0032 0.004 0.004
Brugia malayi hypothetical protein 0.0019 0.0002 0.0003
Mycobacterium ulcerans peptide synthetase Nrp (peptide synthase) 0.0108 0.0284 0.0567
Trichomonas vaginalis phosphofructokinase, putative 0.0029 0.0032 0.0074
Loa Loa (eye worm) hypothetical protein 0.0066 0.0151 0.0286
Loa Loa (eye worm) hypothetical protein 0.0033 0.0044 0.0083
Mycobacterium ulcerans exodeoxyribonuclease III protein XthA 0.0039 0.0064 0.0098
Trichomonas vaginalis aldo-keto reductase, putative 0.0253 0.0747 0.2034
Brugia malayi photoreceptor-specific nuclear receptor 0.0041 0.007 0.0117
Echinococcus multilocularis chromodomain helicase DNA binding protein 4 0.002 0.0003 0.0003
Brugia malayi AMP-binding enzyme family protein 0.0025 0.0019 0.0032
Trichomonas vaginalis alcohol dehydrogenase, putative 0.0062 0.0137 0.0363
Loa Loa (eye worm) hypothetical protein 0.0041 0.007 0.0133
Loa Loa (eye worm) alpha-tubulin 0.0902 0.2816 0.5342
Schistosoma mansoni tubulin subunit beta 0.0278 0.0826 0.1261
Schistosoma mansoni jumonji domain containing protein 0.004 0.0069 0.0105
Brugia malayi Nuclear hormone receptor family member nhr-1 0.0041 0.007 0.0117
Trichomonas vaginalis conserved hypothetical protein 0.0027 0.0025 0.0057
Brugia malayi hypothetical protein 0.0025 0.0018 0.003
Echinococcus multilocularis GTP binding nuclear protein Ran 0.0021 0.0008 0.0008
Mycobacterium tuberculosis Probable polyketide synthase Pks7 0.1056 0.3308 0.7057
Loa Loa (eye worm) CMGC/MAPK/ERK1 protein kinase 0.1068 0.3347 0.6349
Trypanosoma cruzi tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.007 0.0164 0.0428
Echinococcus multilocularis methyl CpG binding domain protein 2 0.0031 0.004 0.004
Echinococcus multilocularis Jumonji, AT rich interactive domain 1B 0.0049 0.0095 0.0095
Brugia malayi AMP-binding enzyme family protein 0.0307 0.0918 0.1543
Trichomonas vaginalis aldo-keto reductase, putative 0.0253 0.0747 0.2034
Trichomonas vaginalis CMGC family protein kinase 0.1068 0.3347 0.9156
Trichomonas vaginalis ABC transporter, half transporter, putative 0.0033 0.0044 0.0109
Loa Loa (eye worm) nuclear hormone receptor-like 1 0.0022 0.0009 0.0016
Onchocerca volvulus 0.0046 0.0087 0.0154
Loa Loa (eye worm) hypothetical protein 0.0198 0.0572 0.1086
Echinococcus multilocularis dnaJ subfamily B 0.1164 0.365 0.365
Loa Loa (eye worm) hypothetical protein 0.0019 0.0001 0.0002
Echinococcus multilocularis aldehyde dehydrogenase, mitochondrial 0.0131 0.0358 0.0358
Trichomonas vaginalis ABC transporter, putative 0.0033 0.0044 0.0109
Trypanosoma brucei DNA polymerase kappa, putative 0.0029 0.0033 0.0079
Loa Loa (eye worm) hypothetical protein 0.0091 0.0231 0.0439
Toxoplasma gondii LsmAD domain-containing protein 0.0025 0.0018 0.0029
Entamoeba histolytica hypothetical protein 0.0045 0.0084 0.0211
Leishmania major beta tubulin 0.1165 0.3655 1
Leishmania major quinone oxidoreductase, putative 0.0062 0.0137 0.0355
Mycobacterium leprae PROBABLE THIOESTERASE TESA 0.0829 0.2583 0.55
Loa Loa (eye worm) cytochrome P450 family protein 0.0038 0.0061 0.0117
Trypanosoma cruzi aldo/keto reductase, putative 0.0073 0.0174 0.0456
Loa Loa (eye worm) hypothetical protein 0.0153 0.0426 0.0809
Onchocerca volvulus Acyl carrier protein, mitochondrial homolog 0.01 0.026 0.046
Mycobacterium ulcerans non-ribosomal peptide synthetase MbtF 0.0108 0.0284 0.0567
Trichomonas vaginalis multidrug resistance protein 1, 2, putative 0.0033 0.0044 0.0109
Schistosoma mansoni tubulin subunit alpha 0.0902 0.2816 0.4301
Trichomonas vaginalis lipid A export ATP-binding/permease protein msba, putative 0.0033 0.0044 0.0109
Brugia malayi aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase 0.0091 0.0231 0.0389
Mycobacterium tuberculosis Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) 0.0039 0.0064 0.0098
Leishmania major oxidoreductase-like protein 0.0062 0.0137 0.0355
Mycobacterium ulcerans non-ribosomal peptide synthetase MbtE 0.0108 0.0284 0.0567
Loa Loa (eye worm) hypothetical protein 0.0019 0.0002 0.0003
Echinococcus granulosus multidrug resistance protein 1 0.0033 0.0044 0.0067
Trichomonas vaginalis aldo-keto reductase, putative 0.0253 0.0747 0.2034
Schistosoma mansoni thyroid hormone receptor 0.0041 0.007 0.0107
Loa Loa (eye worm) hypothetical protein 0.0153 0.0426 0.0809
Echinococcus granulosus 6 phosphofructokinase 0.0106 0.0279 0.0426
Loa Loa (eye worm) hypothetical protein 0.0041 0.007 0.0133
Trichomonas vaginalis phosphofructokinase, putative 0.0106 0.0279 0.0752
Brugia malayi AMP-binding enzyme family protein 0.0937 0.2926 0.4917
Brugia malayi oxidoreductase, aldo/keto reductase family protein 0.0253 0.0747 0.1255
Plasmodium falciparum 3-oxoacyl-acyl-carrier protein synthase I/II 0.025 0.0736 0.201
Echinococcus granulosus lamin dm0 0.0027 0.0026 0.004
Mycobacterium ulcerans DNA polymerase IV 0.0059 0.0128 0.0234
Mycobacterium tuberculosis Conserved hypothetical protein 0.01 0.026 0.0518
Loa Loa (eye worm) alpha-tubulin 0.0902 0.2816 0.5342
Trypanosoma brucei DNA polymerase kappa, putative 0.0059 0.0128 0.0339
Trypanosoma cruzi oxidoreductase, putative 0.0062 0.0137 0.0355
Entamoeba histolytica NADP-dependent alcohol dehydrogenase 0.0062 0.0137 0.0355
Toxoplasma gondii alpha tubulin TUBA1 0.0902 0.2816 0.77
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0041 0.0069 0.017
Brugia malayi NADH-dependent xylose reductase 0.0073 0.0174 0.0292
Trypanosoma cruzi ferric reductase transmembrane protein, putative 0.0034 0.0049 0.0114
Echinococcus granulosus JmjC domain containing protein 4 0.004 0.0069 0.0105
Brugia malayi Protein kinase domain containing protein 0.0022 0.001 0.0018
Echinococcus granulosus acyl carrier protein mitochondrial 0.01 0.026 0.0398
Leishmania major beta tubulin 0.1165 0.3655 1
Brugia malayi nuclear receptor NHR-67 0.0019 0.0001 0.0002
Echinococcus granulosus NADP dependent isocitrate dehydrogenase 0.0032 0.004 0.0062
Trichomonas vaginalis conserved hypothetical protein 0.004 0.0067 0.0171
Trypanosoma cruzi isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0032 0.004 0.009
Brugia malayi isocitrate dehydrogenase 0.0032 0.004 0.0068
Leishmania major d-xylulose reductase, putative 0.0062 0.0137 0.0355
Loa Loa (eye worm) jmjC domain-containing protein 0.004 0.0069 0.013
Echinococcus multilocularis zinc finger protein 0.0044 0.008 0.008
Trypanosoma cruzi beta-ketoacyl synthase family protein, putative 0.025 0.0736 0.1997
Trypanosoma brucei DNA polymerase kappa, putative 0.0059 0.0128 0.0339
Trichomonas vaginalis ran, putative 0.0021 0.0008 0.0009
Entamoeba histolytica hypothetical protein 0.0073 0.0174 0.0457
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0035 0.005 0.0117
Entamoeba histolytica P-glycoprotein-1 0.0033 0.0044 0.01
Brugia malayi glutamate-cysteine ligase modifier subunit 0.0073 0.0174 0.0292
Leishmania major ATP-dependent DEAD/H DNA helicase recQ, putative 0.0031 0.0037 0.0082
Echinococcus granulosus nuclear receptor nhr 48 0.0019 0.0001 0.0002
Trichomonas vaginalis aldo-keto reductase, putative 0.0253 0.0747 0.2034
Mycobacterium ulcerans hypothetical protein 0.0156 0.0436 0.0895
Loa Loa (eye worm) tubulin alpha-3 chain 0.054 0.1662 0.3152
Leishmania major prostaglandin f2-alpha synthase/D-arabinose dehydrogenase 0.0253 0.0747 0.2027
Loa Loa (eye worm) inositol-1 0.0041 0.0069 0.0132
Schistosoma mansoni poly [ADP-ribose] polymerase 0.0462 0.1413 0.2158
Loa Loa (eye worm) tubulin alpha chain 0.0902 0.2816 0.5342
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0095 0.0243 0.0409
Plasmodium vivax tubulin beta chain, putative 0.1165 0.3655 1
Schistosoma mansoni DNA helicase recq5 0.0028 0.0029 0.0045
Toxoplasma gondii PHD-finger domain-containing protein 0.0027 0.0027 0.0054
Brugia malayi Tubulin beta chain 0.0278 0.0826 0.1388
Toxoplasma gondii histone lysine methyltransferase SET1 0.0164 0.0462 0.1245
Trypanosoma brucei cytochrome P450, putative 0.0038 0.0061 0.0156
Plasmodium vivax isocitrate dehydrogenase [NADP], mitochondrial, putative 0.0032 0.004 0.0106
Brugia malayi Nuclear hormone receptor-like 1 0.0022 0.0009 0.0014
Echinococcus granulosus poly (ADP ribose) polymerase 0.0069 0.0161 0.0246
Echinococcus multilocularis replication factor c subunit 1 0.0027 0.0025 0.0025
Schistosoma mansoni methyltransferase-related 0.03 0.0895 0.1367
Schistosoma mansoni smad1 5 8 and 0.0024 0.0017 0.0027
Trichomonas vaginalis bromodomain-containing protein, putative 0.0043 0.0077 0.0199
Leishmania major basic transcription factor 3a, putative 0.0065 0.0146 0.0379
Brugia malayi Bromodomain containing protein 0.0074 0.0176 0.0295
Toxoplasma gondii 3-oxoacyl-acyl-carrier protein synthase I/II, putative 0.025 0.0736 0.1997
Plasmodium vivax 6-phosphofructokinase, putative 0.0029 0.0032 0.0082
Plasmodium falciparum replication factor C subunit 1, putative 0.0027 0.0025 0.0065
Brugia malayi Kringle domain containing protein 0.0022 0.001 0.0018
Schistosoma mansoni tubulin subunit beta 0.1165 0.3655 0.5582
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0022 0.0009 0.0012
Leishmania major ATP-binding cassette protein subfamily B, member 2, putative 0.0033 0.0044 0.01
Trypanosoma cruzi poly(ADP-ribose) polymerase, putative 0.0553 0.1704 0.465
Brugia malayi Phosphopantetheine attachment site family protein 0.01 0.026 0.0437
Echinococcus multilocularis L aminoadipate semialdehyde 0.0091 0.0231 0.0231
Mycobacterium tuberculosis Possible dehydrogenase 0.0062 0.0137 0.0253
Echinococcus granulosus L aminoadipate semialdehyde 0.0091 0.0231 0.0353
Schistosoma mansoni ap endonuclease 0.0039 0.0064 0.0098
Loa Loa (eye worm) hypothetical protein 0.0032 0.0041 0.0077
Brugia malayi Ets-domain containing protein 0.0068 0.0157 0.0264
Schistosoma mansoni hypothetical protein 0.0038 0.0061 0.0094
Trichomonas vaginalis ATP-binding cassette transporter, putative 0.0033 0.0044 0.0109
Schistosoma mansoni DNA helicase recq1 0.0028 0.0029 0.0045
Echinococcus multilocularis aldo keto reductase family 1, member B4 0.0253 0.0747 0.0747
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0066 0.0151 0.023
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0035 0.005 0.0077
Trypanosoma brucei DNA polymerase kappa, putative 0.0059 0.0128 0.0339
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0022 0.0009 0.0009
Leishmania major alpha tubulin 0.0902 0.2816 0.77
Schistosoma mansoni gabp alpha 0.0068 0.0157 0.024

Activities

Activity type Activity value Assay description Source Reference
Potency (functional) 11.2202 uM PubChem BioAssay. qHTS for Agonist of gsp, the Etiologic Mutation Responsible for Fibrous Dysplasia/McCune-Albright Syndrome: qHTS. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) 89.1251 uM PUBCHEM_BIOASSAY: HTS for Inhibitors of HP1-beta Chromodomain Interactions with Methylated Histone Tails. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID488962] ChEMBL. No reference
Potency (functional) 112.2018 uM PUBCHEM_BIOASSAY: qHTS for Inhibitors of Polymerase Iota. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID588623] ChEMBL. No reference

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

Bibliographic References

No literature references available for this target.

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