Detailed information for compound 1397179

Basic information

Technical information
  • TDR Targets ID: 1397179
  • Name: [4-(2,3-dimethylphenyl)piperazin-1-yl]-pyridi n-4-ylmethanone
  • MW: 295.379 | Formula: C18H21N3O
  • H donors: 0 H acceptors: 2 LogP: 2.63 Rotable bonds: 3
    Rule of 5 violations (Lipinski): 1
  • SMILES: O=C(c1ccncc1)N1CCN(CC1)c1cccc(c1C)C
  • InChi: 1S/C18H21N3O/c1-14-4-3-5-17(15(14)2)20-10-12-21(13-11-20)18(22)16-6-8-19-9-7-16/h3-9H,10-13H2,1-2H3
  • InChiKey: CACLSACREDIJKA-UHFFFAOYSA-N  


Substructure search Similarity search

Network

Hover on a compound node to display the structore

Synonyms

  • [4-(2,3-dimethylphenyl)piperazin-1-yl]-(4-pyridyl)methanone
  • [4-(2,3-dimethylphenyl)-1-piperazinyl]-(4-pyridyl)methanone
  • [4-(2,3-dimethylphenyl)piperazin-1-yl]-pyridin-4-yl-methanone
  • MLS000088350
  • SMR000071709
  • ZINC00473857
  • SDCCGMLS-0038881.P002
  • IVK/8073859
  • Oprea1_855576
  • 1-(2,3-dimethylphenyl)-4-isonicotinoylpiperazine

Targets

Known targets for this compound

Species Target name Source Bibliographic reference
Homo sapiens l(3)mbt-like 1 (Drosophila) Starlite/ChEMBL No references
Homo sapiens isocitrate dehydrogenase 1 (NADP+), soluble Starlite/ChEMBL No references
Homo sapiens glucagon-like peptide 1 receptor Starlite/ChEMBL No references
Homo sapiens thyroid stimulating hormone receptor Starlite/ChEMBL No references
Homo sapiens apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3D Starlite/ChEMBL No references
Homo sapiens ATPase family, AAA domain containing 5 Starlite/ChEMBL No references
Homo sapiens ataxin 2 Starlite/ChEMBL No references
Homo sapiens geminin, DNA replication inhibitor Starlite/ChEMBL No references
Homo sapiens apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3G Starlite/ChEMBL No references

Predicted pathogen targets for this compound

By orthology
Species Potential target Known druggable target/s Ortholog Group
Echinococcus granulosus NADP dependent isocitrate dehydrogenase Get druggable targets OG5_127057 All targets in OG5_127057
Trypanosoma brucei isocitrate dehydrogenase, putative Get druggable targets OG5_127057 All targets in OG5_127057
Schistosoma mansoni NADP-specific isocitrate dehydrogenase Get druggable targets OG5_127057 All targets in OG5_127057
Brugia malayi follicle stimulating hormone receptor Get druggable targets OG5_130089 All targets in OG5_130089
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase Get druggable targets OG5_127057 All targets in OG5_127057
Schistosoma japonicum ko:K00031 isocitrate dehydrogenase [EC1.1.1.42], putative Get druggable targets OG5_127057 All targets in OG5_127057
Loa Loa (eye worm) follicle stimulating hormone receptor Get druggable targets OG5_130089 All targets in OG5_130089
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase Get druggable targets OG5_127057 All targets in OG5_127057
Mycobacterium tuberculosis Probable isocitrate dehydrogenase [NADP] Icd1 (oxalosuccinate decarboxylase) (IDH) (NADP+-specific ICDH) (IDP) Get druggable targets OG5_127057 All targets in OG5_127057
Trypanosoma brucei gambiense isocitrate dehydrogenase, putative Get druggable targets OG5_127057 All targets in OG5_127057
Candida albicans cytosolic NADP-specific isocitrate dehydrogenase. Get druggable targets OG5_127057 All targets in OG5_127057
Neospora caninum hypothetical protein Get druggable targets OG5_127057 All targets in OG5_127057
Trypanosoma cruzi isocitrate dehydrogenase, putative Get druggable targets OG5_127057 All targets in OG5_127057
Echinococcus multilocularis endonuclease exonuclease phosphatase Get druggable targets OG5_130415 All targets in OG5_130415
Loa Loa (eye worm) isocitrate dehydrogenase Get druggable targets OG5_127057 All targets in OG5_127057
Brugia malayi isocitrate dehydrogenase Get druggable targets OG5_127057 All targets in OG5_127057
Plasmodium yoelii isocitrate dehydrogenase, NADP-dependent, putative Get druggable targets OG5_127057 All targets in OG5_127057
Leishmania donovani isocitrate dehydrogenase [NADP], mitochondrial precursor, putative Get druggable targets OG5_127057 All targets in OG5_127057
Candida albicans Mitochondrial NADP-specific isocitrate dehydrogenase Get druggable targets OG5_127057 All targets in OG5_127057
Brugia malayi Isocitrate dehydrogenase Get druggable targets OG5_127057 All targets in OG5_127057
Leishmania braziliensis isocitrate dehydrogenase [NADP], mitochondrial precursor, putative Get druggable targets OG5_127057 All targets in OG5_127057
Schistosoma japonicum Lethal(3)malignant brain tumor-like 4 protein, putative Get druggable targets OG5_130415 All targets in OG5_130415
Theileria parva isocitrate dehydrogenase (NADP+), putative Get druggable targets OG5_127057 All targets in OG5_127057
Trypanosoma cruzi isocitrate dehydrogenase [NADP], mitochondrial precursor, putative Get druggable targets OG5_127057 All targets in OG5_127057
Trypanosoma congolense isocitrate dehydrogenase, putative Get druggable targets OG5_127057 All targets in OG5_127057
Toxoplasma gondii isocitrate dehydrogenase Get druggable targets OG5_127057 All targets in OG5_127057
Babesia bovis isocitrate dehydrogenase, NADP-dependent family protein Get druggable targets OG5_127057 All targets in OG5_127057
Leishmania infantum isocitrate dehydrogenase [NADP], mitochondrial precursor, putative Get druggable targets OG5_127057 All targets in OG5_127057
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase Get druggable targets OG5_127057 All targets in OG5_127057
Schistosoma mansoni hypothetical protein Get druggable targets OG5_130415 All targets in OG5_130415
Plasmodium yoelii isocitrate dehydrogenase, NADP-dependent Get druggable targets OG5_127057 All targets in OG5_127057
Schistosoma japonicum Lethal(3)malignant brain tumor-like 3 protein, putative Get druggable targets OG5_130415 All targets in OG5_130415
Trypanosoma brucei isocitrate dehydrogenase [NADP], mitochondrial precursor, putative Get druggable targets OG5_127057 All targets in OG5_127057
Trypanosoma congolense isocitrate dehydrogenase, putative Get druggable targets OG5_127057 All targets in OG5_127057
Candida albicans Mitochondrial NADP-specific isocitrate dehydrogenase Get druggable targets OG5_127057 All targets in OG5_127057
Toxoplasma gondii isocitrate dehydrogenase Get druggable targets OG5_127057 All targets in OG5_127057
Candida albicans C terminus of cytosolic NADP-specific isocitrate dehydrogenase. Get druggable targets OG5_127057 All targets in OG5_127057
Echinococcus multilocularis isocitrate dehydrogenase Get druggable targets OG5_127057 All targets in OG5_127057
Echinococcus multilocularis isocitrate dehydrogenase 2 (NADP+) Get druggable targets OG5_127057 All targets in OG5_127057
Plasmodium vivax isocitrate dehydrogenase [NADP], mitochondrial, putative Get druggable targets OG5_127057 All targets in OG5_127057
Trypanosoma brucei gambiense isocitrate dehydrogenase [NADP], mitochondrial precursor, putative Get druggable targets OG5_127057 All targets in OG5_127057
Candida albicans N terminus of cytosolic NADP-specific isocitrate dehydrogenase. Get druggable targets OG5_127057 All targets in OG5_127057
Plasmodium falciparum isocitrate dehydrogenase [NADP], mitochondrial Get druggable targets OG5_127057 All targets in OG5_127057
Leishmania mexicana isocitrate dehydrogenase [NADP], mitochondrial precursor, putative Get druggable targets OG5_127057 All targets in OG5_127057
Plasmodium knowlesi isocitrate dehydrogenase [NADP], mitochondrial, putative Get druggable targets OG5_127057 All targets in OG5_127057
Echinococcus multilocularis atpase aaa+ type core atpase aaa type core Get druggable targets OG5_139225 All targets in OG5_139225
Leishmania major isocitrate dehydrogenase [NADP], mitochondrial precursor, putative Get druggable targets OG5_127057 All targets in OG5_127057
Echinococcus granulosus endonuclease exonuclease phosphatase Get druggable targets OG5_130415 All targets in OG5_130415
Plasmodium berghei isocitrate dehydrogenase [NADP], mitochondrial, putative Get druggable targets OG5_127057 All targets in OG5_127057
Neospora caninum Isocitrate dehydrogenase-like protein, related Get druggable targets OG5_127057 All targets in OG5_127057
By sequence similarity to non orthologous known druggable targets
Species Potential target Known druggable target Length Alignment span Identity
Brugia malayi Hypothetical 65.5 kDa Trp-Asp repeats containing protein F02E8.5 inchromosome X geminin, DNA replication inhibitor 209 aa 176 aa 27.8 %
Loa Loa (eye worm) pigment dispersing factor receptor c glucagon-like peptide 1 receptor 463 aa 388 aa 25.8 %
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Echinococcus granulosus o acyltransferase membrane bound domain 0.0155 0.1093 0.0876
Brugia malayi hypothetical protein 0.0365 0.2932 0.2932
Plasmodium vivax diacylglycerol O-acyltransferase, putative 0.0923 0.7823 1
Trypanosoma brucei glycerol uptake protein, putative 0.0155 0.1093 1
Toxoplasma gondii acyl-CoA:diacylglycerol acyltransferase 1-related enzyme 0.0923 0.7823 1
Schistosoma mansoni sodium-bile acid cotransporter related 0.0475 0.3896 0.3838
Schistosoma mansoni membrane-bound acyltransferase/hhat 0.0155 0.1093 0.1009
Loa Loa (eye worm) MBOAT family protein 0.0155 0.1093 0.1093
Entamoeba histolytica membrane-bound O-acyltransferase (MBOAT ) family protein 0.0155 0.1093 0.5
Schistosoma mansoni hypothetical protein 0.0205 0.1527 0.1446
Loa Loa (eye worm) hypothetical protein 0.006 0.0261 0.0261
Trypanosoma cruzi glycerol uptake protein, putative 0.0155 0.1093 1
Schistosoma mansoni leukocyte receptor cluster (lrc) member 4 protein 0.0155 0.1093 0.1009
Trypanosoma brucei glycerol uptake protein, putative 0.0155 0.1093 1
Schistosoma mansoni diacylglycerol O-acyltransferase 1 0.0923 0.7823 0.7803
Leishmania major glycerol uptake protein, putative 0.0155 0.1093 1
Trichomonas vaginalis porcupine, putative 0.0155 0.1093 0.5
Brugia malayi MBOAT family protein 0.0155 0.1093 0.1093
Echinococcus granulosus endonuclease exonuclease phosphatase 0.0227 0.1723 0.1521
Echinococcus multilocularis o acyltransferase (membrane bound) domain 0.0155 0.1093 0.0876
Entamoeba histolytica membrane-bound O-acyltransferase (MBOAT ) family protein 0.0155 0.1093 0.5
Trichomonas vaginalis transmembrane protein nessy, putative 0.0155 0.1093 0.5
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.006 0.0261 0.0261
Loa Loa (eye worm) hypothetical protein 0.0155 0.1093 0.1093
Schistosoma mansoni sex comb on midleg homolog 0.0058 0.0238 0.0146
Loa Loa (eye worm) hypothetical protein 0.0041 0.0094 0.0094
Loa Loa (eye worm) hypothetical protein 0.0365 0.2932 0.2932
Leishmania major glycerol uptake protein, putative 0.0155 0.1093 1
Loa Loa (eye worm) hypothetical protein 0.0155 0.1093 0.1093
Schistosoma mansoni sterol O-acyltransferase 1 0.0155 0.1093 0.1009
Echinococcus multilocularis sterol O acyltransferase 1 0.0155 0.1093 0.0876
Schistosoma mansoni scm-relatedprotein containing 4 mbt domains (sfmbt) 0.0058 0.0238 0.0146
Echinococcus multilocularis geminin 0.0205 0.1527 0.132
Loa Loa (eye worm) diacylglycerol acyltransferase 0.0923 0.7823 0.7823
Brugia malayi MBOAT family protein 0.0155 0.1093 0.1093
Brugia malayi MBOAT family protein 0.0155 0.1093 0.1093
Toxoplasma gondii acyl-CoA:cholesterol acyltransferase alpha ACAT1-alpha 0.0923 0.7823 1
Echinococcus multilocularis diacylglycerol O acyltransferase 1 0.0923 0.7823 0.777
Brugia malayi MBOAT family protein 0.0155 0.1093 0.1093
Echinococcus multilocularis protein cysteine N palmitoyltransferase 0.0155 0.1093 0.0876
Entamoeba histolytica hypothetical protein, conserved 0.0155 0.1093 0.5
Leishmania major glycerol uptake protein, putative 0.0155 0.1093 1
Leishmania major hypothetical protein, conserved 0.0155 0.1093 1
Schistosoma mansoni o-acyltransferase (membrane bound) domain containing protein 0.0155 0.1093 0.1009
Trichomonas vaginalis conserved hypothetical protein 0.0155 0.1093 0.5
Schistosoma mansoni zinc finger protein 0.0155 0.1093 0.1009
Plasmodium falciparum diacylglycerol O-acyltransferase 0.0923 0.7823 1
Brugia malayi Hhat protein 0.0155 0.1093 0.1093
Trypanosoma cruzi GUP1, putative 0.0155 0.1093 1
Loa Loa (eye worm) pigment dispersing factor receptor c 0.006 0.0261 0.0261
Toxoplasma gondii hypothetical protein 0.0155 0.1093 0.1397
Brugia malayi follicle stimulating hormone receptor 0.028 0.2185 0.2185
Entamoeba histolytica hypothetical protein 0.0155 0.1093 0.5
Schistosoma mansoni sex comb on midleg homolog 0.0058 0.0238 0.0146
Echinococcus granulosus Membrane bound O acyl transferase MBOAT 0.0155 0.1093 0.0876
Loa Loa (eye worm) hhat protein 0.0155 0.1093 0.1093
Schistosoma mansoni hypothetical protein 0.035 0.2802 0.2734
Schistosoma mansoni hypothetical protein 0.0155 0.1093 0.1009
Echinococcus granulosus o acyltransferase membrane bound domain 0.0155 0.1093 0.0876
Echinococcus granulosus membrane bound acyltransferase:hhat 0.0155 0.1093 0.0876
Loa Loa (eye worm) hypothetical protein 0.0058 0.0238 0.0238
Trichomonas vaginalis conserved hypothetical protein 0.0155 0.1093 0.5
Echinococcus multilocularis o acyltransferase (membrane bound) domain 0.0155 0.1093 0.0876
Loa Loa (eye worm) MBCTL1 0.0066 0.0308 0.0308
Brugia malayi MBOAT family protein 0.0155 0.1093 0.1093
Trypanosoma cruzi glycerol uptake protein, putative 0.0155 0.1093 1
Echinococcus granulosus geminin 0.0205 0.1527 0.132
Leishmania major glycerol uptake protein, putative 0.0155 0.1093 1
Onchocerca volvulus 0.0155 0.1093 0.0876
Echinococcus multilocularis o acyltransferase (membrane bound) domain 0.0155 0.1093 0.0876
Loa Loa (eye worm) hypothetical protein 0.0066 0.0308 0.0308
Loa Loa (eye worm) membrane bound O-acyltransferase domain containing 1 0.0155 0.1093 0.1093
Leishmania major glycerol uptake protein, putative 0.0155 0.1093 1
Loa Loa (eye worm) MBOAT family protein 0.0155 0.1093 0.1093
Loa Loa (eye worm) hypothetical protein 0.0155 0.1093 0.1093
Loa Loa (eye worm) follicle stimulating hormone receptor 0.028 0.2185 0.2185
Entamoeba histolytica vacuolar protein sorting 26 0.0155 0.1093 0.5
Echinococcus multilocularis atpase aaa+ type core atpase aaa type core 0.0979 0.8316 0.8275
Trypanosoma cruzi glycerol uptake protein, putative 0.0155 0.1093 1
Trypanosoma cruzi GUP1, putative 0.0155 0.1093 1
Echinococcus multilocularis Membrane bound O acyl transferase, MBOAT 0.0155 0.1093 0.0876
Echinococcus granulosus protein cysteine N palmitoyltransferase 0.0155 0.1093 0.0876
Echinococcus granulosus suppression of tumorigenicity 18 protein 0.0066 0.0308 0.0072
Schistosoma mansoni o-acyltransferase (membrane bound) domain containing protein 0.0155 0.1093 0.1009
Onchocerca volvulus 0.0365 0.2932 0.2759
Entamoeba histolytica membrane-bound O-acyltransferase (MBOAT ) family protein 0.0155 0.1093 0.5
Brugia malayi diacylglycerol acyltransferase 0.0923 0.7823 0.7823
Loa Loa (eye worm) MBOAT family protein 0.0155 0.1093 0.1093
Loa Loa (eye worm) hypothetical protein 0.0155 0.1093 0.1093
Schistosoma mansoni o-acyltransferase (membrane bound) domain containing protein 0.0155 0.1093 0.1009
Loa Loa (eye worm) mbt repeat family protein 0.0058 0.0238 0.0238
Echinococcus granulosus diacylglycerol O acyltransferase 1 0.0923 0.7823 0.777
Trichomonas vaginalis conserved hypothetical protein 0.0155 0.1093 0.5
Loa Loa (eye worm) hhat protein 0.0155 0.1093 0.1093
Brugia malayi C2-HC type zinc finger protein C.e-MyT1 0.0066 0.0308 0.0308
Echinococcus multilocularis suppression of tumorigenicity 18 protein 0.0066 0.0308 0.0072
Brugia malayi Calcitonin receptor-like protein seb-1 0.006 0.0261 0.0261
Echinococcus multilocularis lysophospholipid acyltransferase 7 0.0155 0.1093 0.0876
Echinococcus granulosus o acyltransferase membrane bound domain 0.0155 0.1093 0.0876
Treponema pallidum alginate O-acetylation protein (algI) 0.0155 0.1093 0.5
Echinococcus multilocularis endonuclease exonuclease phosphatase 0.0227 0.1723 0.1521
Brugia malayi latrophilin 2 splice variant baaae 0.0041 0.0094 0.0094
Loa Loa (eye worm) hypothetical protein 0.0768 0.6464 0.6464
Echinococcus granulosus histone acetyltransferase MYST2 0.0066 0.0308 0.0072
Schistosoma mansoni sodium-bile acid cotransporter 0.0696 0.5837 0.5797
Echinococcus multilocularis membrane bound acyltransferase:hhat 0.0155 0.1093 0.0876
Echinococcus granulosus sterol O acyltransferase 1 0.0155 0.1093 0.0876
Schistosoma mansoni myelin transcription factor 1 myt1 0.0066 0.0308 0.0216
Echinococcus multilocularis histone acetyltransferase MYST2 0.0066 0.0308 0.0072
Schistosoma mansoni hypothetical protein 0.0205 0.1527 0.1446
Echinococcus granulosus lysophospholipid acyltransferase 7 0.0155 0.1093 0.0876
Brugia malayi mbt repeat family protein 0.0058 0.0238 0.0238
Brugia malayi mbt repeat family protein 0.0058 0.0238 0.0238

Activities

Activity type Activity value Assay description Source Reference
Potency (functional) 0.0282 uM PubChem BioAssay. qHTS for Inhibitors of ATXN expression. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) = 1.7783 um PUBCHEM_BIOASSAY: qHTS Assay for the Inhibitors of L3MBTL1. (Class of assay: confirmatory) [Related pubchem assays: 485292 (Probe Development Summary for Inhibitors of L3MBTL1)] ChEMBL. No reference
Potency (functional) 2.5119 uM PubChem BioAssay. qHTS of GLP-1 Receptor Inverse Agonists (Inhibition Mode). (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) = 5.0119 um PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Thyroid Stimulating Hormone Receptor. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) 5.8048 uM PubChem BioAssay. A quantitative high throughput screen for small molecules that induce DNA re-replication in MCF 10a normal breast cells. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) 7.3078 uM PUBCHEM_BIOASSAY: qHTS screen for small molecules that inhibit ELG1-dependent DNA repair in human embryonic kidney (HEK293T) cells expressing luciferase-tagged ELG1. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID493107, AID493125] ChEMBL. No reference
Potency (functional) 9.2 uM PubChem BioAssay. qHTS for induction of synthetic lethality in tumor cells producing 2HG: qHTS for the HT-1080-NT fibrosarcoma cell line. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) 9.9425 uM PubChem BioAssay. qHTS for inhibitors of Vif-A3F interactions: Cherry picks counterscreen. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) 10 uM PubChem BioAssay. qHTS for Inhibitors of Vif-A3G Interactions: qHTS. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) 11.5821 uM PubChem BioAssay. A quantitative high throughput screen for small molecules that induce DNA re-replication in SW480 colon adenocarcinoma cells. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) 12.5168 uM PubChem BioAssay. qHTS for inhibitors of Vif-A3G interactions: Cherry picks counterscreen. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) 14.0441 uM PubChem BioAssay. qHTS for inhibitors of Vif-A3F interactions: Cherry picks. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) 16.3535 uM PUBCHEM_BIOASSAY: qHTS for Inhibitors of binding or entry into cells for Lassa Virus. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID463114, AID540249] ChEMBL. No reference
Potency (functional) = 22.3872 um PUBCHEM_BIOASSAY: qHTS Assay for Modulators of Lamin A Splicing. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) 23.1093 uM PUBCHEM_BIOASSAY: qHTS Assay for Inhibitors of RanGTP induced Rango (Ran-regulated importin-beta cargo) - Importin beta complex dissociation. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID540262] ChEMBL. No reference
Potency (functional) = 35.4813 um PUBCHEM_BIOASSAY: qHTS Assay for Enhancers of SMN2 Splice Variant Expression. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) 89.1251 uM PUBCHEM_BIOASSAY: HTS for Inhibitors of HP1-beta Chromodomain Interactions with Methylated Histone Tails. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID488962] ChEMBL. No reference

Phenotypes

Whole-cell/tissue/organism interactions

Species name Source Reference Is orphan
Homo sapiens ChEMBL23

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

Bibliographic References

No literature references available for this target.

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