Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Brugia malayi | Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative | 0.0036 | 0.0267 | 0.0267 |
Mycobacterium ulcerans | esterase/lipase LipP | 0.0036 | 0.0267 | 0.8283 |
Brugia malayi | exodeoxyribonuclease III family protein | 0.0019 | 0.0035 | 0.0035 |
Entamoeba histolytica | hypothetical protein | 0.0148 | 0.1791 | 1 |
Schistosoma mansoni | steroid hormone receptor ad4bp | 0.0032 | 0.0217 | 0.1052 |
Mycobacterium tuberculosis | Probable conserved lipoprotein | 0.0036 | 0.0267 | 0.0814 |
Loa Loa (eye worm) | acetyltransferase | 0.0158 | 0.1927 | 0.1927 |
Brugia malayi | Nuclear hormone receptor family member nhr-14 | 0.0032 | 0.0217 | 0.0217 |
Schistosoma mansoni | coup transcription factor | 0.0032 | 0.0217 | 0.1052 |
Schistosoma mansoni | hypothetical protein | 0.0168 | 0.2064 | 1 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-49 | 0.0032 | 0.0217 | 0.0217 |
Schistosoma mansoni | retinoid-x-receptor (RXR) | 0.0017 | 0.0012 | 0.0057 |
Brugia malayi | Nuclear hormone receptor family member nhr-49 | 0.0032 | 0.0217 | 0.0217 |
Schistosoma mansoni | ap endonuclease | 0.0019 | 0.0035 | 0.017 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0095 | 0.1075 | 0.1075 |
Trichomonas vaginalis | penicillin-binding protein, putative | 0.0036 | 0.0267 | 0.6134 |
Loa Loa (eye worm) | hypothetical protein | 0.0036 | 0.0267 | 0.0267 |
Mycobacterium tuberculosis | Probable hydrolase | 0.0036 | 0.0267 | 0.0814 |
Mycobacterium tuberculosis | Probable esterase/lipase LipP | 0.0036 | 0.0267 | 0.0814 |
Brugia malayi | hypothetical protein | 0.0017 | 0.0012 | 0.0012 |
Plasmodium vivax | hypothetical protein, conserved | 0.0036 | 0.0267 | 0.6134 |
Loa Loa (eye worm) | hypothetical protein | 0.0751 | 1 | 1 |
Mycobacterium ulcerans | fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE | 0.0036 | 0.0267 | 0.8283 |
Echinococcus granulosus | Nuclear hormone receptor family member nhr 41 | 0.0032 | 0.0217 | 0.0217 |
Loa Loa (eye worm) | hypothetical protein | 0.0036 | 0.0267 | 0.0267 |
Brugia malayi | Nuclear hormone receptor-like 1 | 0.0017 | 0.0012 | 0.0012 |
Echinococcus multilocularis | geminin | 0.0168 | 0.2064 | 0.2064 |
Wolbachia endosymbiont of Brugia malayi | exonuclease III | 0.0019 | 0.0035 | 0.5 |
Loa Loa (eye worm) | nuclear hormone receptor-like 1 | 0.0017 | 0.0012 | 0.0012 |
Brugia malayi | Iron-sulfur cluster assembly accessory protein | 0.0153 | 0.1866 | 0.1866 |
Echinococcus granulosus | lamin dm0 | 0.0053 | 0.0508 | 0.0508 |
Loa Loa (eye worm) | intermediate filament protein | 0.0053 | 0.0508 | 0.0508 |
Echinococcus multilocularis | cytoplasmic intermediate filament protein | 0.0026 | 0.0132 | 0.0132 |
Loa Loa (eye worm) | hypothetical protein | 0.0017 | 0.0012 | 0.0012 |
Echinococcus granulosus | retinoic acid receptor rxr beta a | 0.0032 | 0.0217 | 0.0217 |
Mycobacterium ulcerans | putative regulatory protein | 0.0039 | 0.0315 | 1 |
Echinococcus multilocularis | serotonin receptor | 0.0161 | 0.1977 | 0.1977 |
Brugia malayi | Steroid receptor seven-up type 2 | 0.0032 | 0.0217 | 0.0217 |
Trichomonas vaginalis | penicillin-binding protein, putative | 0.0036 | 0.0267 | 0.6134 |
Echinococcus multilocularis | hepatocyte nuclear factor 4 alpha | 0.0032 | 0.0217 | 0.0217 |
Echinococcus granulosus | histone acetyltransferase KAT2B | 0.0153 | 0.1867 | 0.1867 |
Mycobacterium leprae | Probable lipase LipE | 0.0036 | 0.0267 | 0.5 |
Schistosoma mansoni | ap endonuclease | 0.0019 | 0.0035 | 0.017 |
Echinococcus granulosus | COUP TF:Svp nuclear hormone receptor | 0.0032 | 0.0217 | 0.0217 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0036 | 0.0267 | 0.2325 |
Echinococcus multilocularis | nuclear receptor 2DBD gamma | 0.0032 | 0.0217 | 0.0217 |
Brugia malayi | beta-lactamase | 0.0036 | 0.0267 | 0.0267 |
Mycobacterium tuberculosis | Conserved protein | 0.0036 | 0.0267 | 0.0814 |
Loa Loa (eye worm) | hypothetical protein | 0.0017 | 0.0012 | 0.0012 |
Mycobacterium tuberculosis | Conserved protein | 0.0036 | 0.0267 | 0.0814 |
Mycobacterium tuberculosis | Probable esterase LipL | 0.0036 | 0.0267 | 0.0814 |
Brugia malayi | Protein kinase domain containing protein | 0.0092 | 0.1031 | 0.1031 |
Echinococcus granulosus | nuclear receptor 2DBD gamma | 0.0032 | 0.0217 | 0.0217 |
Echinococcus granulosus | lamin | 0.0053 | 0.0508 | 0.0508 |
Entamoeba histolytica | hypothetical protein | 0.0092 | 0.1031 | 0.5674 |
Echinococcus granulosus | FTZ F1 alpha | 0.0032 | 0.0217 | 0.0217 |
Brugia malayi | Nuclear hormone receptor family member nhr-25 | 0.0032 | 0.0217 | 0.0217 |
Schistosoma mansoni | survival motor neuron protein | 0.0153 | 0.1866 | 0.9043 |
Mycobacterium ulcerans | hypothetical protein | 0.0036 | 0.0267 | 0.8283 |
Echinococcus granulosus | Basic leucine zipper bZIP transcription | 0.0148 | 0.1791 | 0.1791 |
Brugia malayi | MH2 domain containing protein | 0.0235 | 0.2983 | 0.2983 |
Brugia malayi | photoreceptor-specific nuclear receptor | 0.0289 | 0.3711 | 0.3711 |
Echinococcus granulosus | geminin | 0.0168 | 0.2064 | 0.2064 |
Onchocerca volvulus | 0.0153 | 0.1866 | 0.5447 | |
Loa Loa (eye worm) | hypothetical protein | 0.0032 | 0.0217 | 0.0217 |
Brugia malayi | nuclear receptor RXR | 0.0017 | 0.0012 | 0.0012 |
Brugia malayi | beta-lactamase family protein | 0.0036 | 0.0267 | 0.0267 |
Brugia malayi | cytoplasmic intermediate filament protein | 0.0029 | 0.0171 | 0.0171 |
Schistosoma mansoni | single-minded | 0.0053 | 0.0502 | 0.2432 |
Loa Loa (eye worm) | hypothetical protein | 0.0032 | 0.0217 | 0.0217 |
Entamoeba histolytica | protein kinase domain containing protein | 0.0092 | 0.1031 | 0.5674 |
Trichomonas vaginalis | esterase, putative | 0.0036 | 0.0267 | 0.6134 |
Brugia malayi | intermediate filament protein | 0.0053 | 0.0508 | 0.0508 |
Loa Loa (eye worm) | CMGC/DYRK/DYRK1 protein kinase | 0.0092 | 0.1031 | 0.1031 |
Schistosoma mansoni | lamin | 0.0053 | 0.0508 | 0.2463 |
Brugia malayi | acetyltransferase, GNAT family protein | 0.0158 | 0.1927 | 0.1927 |
Schistosoma mansoni | family S12 unassigned peptidase (S12 family) | 0.0036 | 0.0267 | 0.1293 |
Mycobacterium ulcerans | lipase LipD | 0.0036 | 0.0267 | 0.8283 |
Loa Loa (eye worm) | hypothetical protein | 0.0036 | 0.0267 | 0.0267 |
Trichomonas vaginalis | D-aminoacylase, putative | 0.0036 | 0.0267 | 0.6134 |
Loa Loa (eye worm) | hypothetical protein | 0.0032 | 0.0217 | 0.0217 |
Entamoeba histolytica | hypothetical protein | 0.0148 | 0.1791 | 1 |
Schistosoma mansoni | photoreceptor-specific nuclear receptor related | 0.0032 | 0.0217 | 0.1052 |
Echinococcus multilocularis | FTZ F1 alpha | 0.0032 | 0.0217 | 0.0217 |
Brugia malayi | Nuclear hormone receptor family member nhr-1 | 0.0032 | 0.0217 | 0.0217 |
Brugia malayi | Nuclear hormone receptor family member nhr-41 | 0.0032 | 0.0217 | 0.0217 |
Brugia malayi | hypothetical protein | 0.0178 | 0.2197 | 0.2197 |
Entamoeba histolytica | protein kinase, putative | 0.0092 | 0.1031 | 0.5674 |
Plasmodium vivax | histone acetyltransferase GCN5, putative | 0.0046 | 0.0413 | 1 |
Onchocerca volvulus | 0.0039 | 0.0315 | 0.0322 | |
Schistosoma mansoni | ecdysone-induced protein 78c (dr-78) | 0.0017 | 0.0012 | 0.0057 |
Echinococcus multilocularis | FTZ F1 nuclear receptor protein | 0.0032 | 0.0217 | 0.0217 |
Trypanosoma brucei | CMGC/DYRK protein kinase, putative | 0.0092 | 0.1031 | 1 |
Brugia malayi | nuclear receptor NHR-88 | 0.0032 | 0.0217 | 0.0217 |
Echinococcus multilocularis | Nuclear hormone receptor family member nhr 41 | 0.0032 | 0.0217 | 0.0217 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0036 | 0.0267 | 0.2325 |
Echinococcus granulosus | survival motor neuron protein 1 | 0.0751 | 1 | 1 |
Echinococcus multilocularis | ecdysone induced protein 78C | 0.0032 | 0.0217 | 0.0217 |
Loa Loa (eye worm) | hypothetical protein | 0.0091 | 0.1025 | 0.1025 |
Brugia malayi | Nuclear hormone receptor family member nhr-19 | 0.0032 | 0.0217 | 0.0217 |
Loa Loa (eye worm) | exodeoxyribonuclease III family protein | 0.0019 | 0.0035 | 0.0035 |
Echinococcus granulosus | biogenic amine 5HT receptor | 0.0161 | 0.1977 | 0.1977 |
Loa Loa (eye worm) | hypothetical protein | 0.0161 | 0.1977 | 0.1977 |
Echinococcus granulosus | hepatocyte nuclear factor 4 alpha | 0.0032 | 0.0217 | 0.0217 |
Schistosoma mansoni | nuclear receptor 2DBD-gamma | 0.0032 | 0.0217 | 0.1052 |
Loa Loa (eye worm) | hypothetical protein | 0.0053 | 0.0508 | 0.0508 |
Trichomonas vaginalis | D-aminoacylase, putative | 0.0036 | 0.0267 | 0.6134 |
Loa Loa (eye worm) | hypothetical protein | 0.0017 | 0.0012 | 0.0012 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-40 | 0.0032 | 0.0217 | 0.0217 |
Loa Loa (eye worm) | transcription factor SMAD2 | 0.0235 | 0.2983 | 0.2983 |
Schistosoma mansoni | biogenic amine (5HT) receptor | 0.0161 | 0.1977 | 0.9582 |
Loa Loa (eye worm) | hypothetical protein | 0.0036 | 0.0267 | 0.0267 |
Mycobacterium tuberculosis | Possible penicillin-binding protein | 0.0228 | 0.2879 | 1 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-41 | 0.0032 | 0.0217 | 0.0217 |
Schistosoma mansoni | RAR-like nuclear receptor | 0.0032 | 0.0217 | 0.1052 |
Mycobacterium tuberculosis | Probable lipase LipE | 0.0036 | 0.0267 | 0.0814 |
Brugia malayi | hypothetical protein | 0.0255 | 0.3245 | 0.3245 |
Loa Loa (eye worm) | hypothetical protein | 0.0025 | 0.0119 | 0.0119 |
Echinococcus granulosus | intermediate filament protein | 0.0053 | 0.0508 | 0.0508 |
Brugia malayi | PAS domain containing protein | 0.0053 | 0.0502 | 0.0502 |
Echinococcus granulosus | ecdysone induced protein 78C | 0.0032 | 0.0217 | 0.0217 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0095 | 0.1075 | 0.5208 |
Loa Loa (eye worm) | steroid hormone receptor | 0.0032 | 0.0217 | 0.0217 |
Brugia malayi | GTP-binding regulatory protein Gs alpha-S chain, putative | 0.0095 | 0.1075 | 0.1075 |
Toxoplasma gondii | ABC1 family protein | 0.0036 | 0.0267 | 0.6134 |
Toxoplasma gondii | histone lysine acetyltransferase GCN5-A | 0.0046 | 0.0413 | 1 |
Giardia lamblia | Histone acetyltransferase GCN5 | 0.0043 | 0.036 | 1 |
Brugia malayi | ecdysteroid receptor | 0.0032 | 0.0217 | 0.0217 |
Schistosoma mansoni | FTZ-F1 nuclear receptor-like protein | 0.0032 | 0.0217 | 0.1052 |
Brugia malayi | Nuclear hormone receptor family member nhr-31 | 0.0032 | 0.0217 | 0.0217 |
Schistosoma mansoni | family S12 unassigned peptidase (S12 family) | 0.0036 | 0.0267 | 0.1293 |
Schistosoma mansoni | retinoid-x-receptor (RXR) | 0.0032 | 0.0217 | 0.1052 |
Schistosoma mansoni | gcn5proteinral control of amino-acid synthesis 5-like 2 gcnl2 | 0.0158 | 0.1927 | 0.9337 |
Brugia malayi | Nuclear hormone receptor family member nhr-3 | 0.0032 | 0.0217 | 0.0217 |
Loa Loa (eye worm) | hypothetical protein | 0.0036 | 0.0267 | 0.0267 |
Brugia malayi | bHLH-PAS transcription factor | 0.0039 | 0.0315 | 0.0315 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-31 | 0.0032 | 0.0217 | 0.0217 |
Mycobacterium tuberculosis | Possible conserved lipoprotein LpqK | 0.0036 | 0.0267 | 0.0814 |
Mycobacterium tuberculosis | Probable lipase LipD | 0.0036 | 0.0267 | 0.0814 |
Echinococcus granulosus | single minded 2 | 0.0039 | 0.0315 | 0.0315 |
Loa Loa (eye worm) | cytoplasmic intermediate filament protein | 0.0029 | 0.0171 | 0.0171 |
Echinococcus multilocularis | lamin dm0 | 0.0053 | 0.0508 | 0.0508 |
Loa Loa (eye worm) | beta-lactamase | 0.0036 | 0.0267 | 0.0267 |
Brugia malayi | nuclear hormone receptor | 0.0032 | 0.0217 | 0.0217 |
Entamoeba histolytica | protein kinase, putative | 0.0092 | 0.1031 | 0.5674 |
Brugia malayi | Nuclear hormone receptor family member nhr-25 | 0.0032 | 0.0217 | 0.0217 |
Schistosoma mansoni | lamin | 0.0053 | 0.0508 | 0.2463 |
Echinococcus multilocularis | nuclear receptor subfamily 1 group D | 0.0017 | 0.0012 | 0.0012 |
Onchocerca volvulus | 0.0036 | 0.0267 | 0.0164 | |
Brugia malayi | beta-lactamase family protein | 0.0036 | 0.0267 | 0.0267 |
Entamoeba histolytica | hypothetical protein | 0.0148 | 0.1791 | 1 |
Schistosoma mansoni | aryl hydrocarbon receptor | 0.0053 | 0.0502 | 0.2432 |
Trichomonas vaginalis | cat eye syndrome critical region protein 2, cscr2, putative | 0.0046 | 0.0413 | 1 |
Echinococcus granulosus | cytoplasmic intermediate filament protein | 0.0026 | 0.0132 | 0.0132 |
Schistosoma mansoni | hypothetical protein | 0.0153 | 0.1866 | 0.9043 |
Echinococcus multilocularis | beta LACTamase domain containing family member | 0.0036 | 0.0267 | 0.0267 |
Onchocerca volvulus | 0.0053 | 0.0508 | 0.0961 | |
Echinococcus multilocularis | transfer RNA-Lys | 0.0039 | 0.0315 | 0.0315 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0095 | 0.1075 | 0.5208 |
Schistosoma mansoni | retinoic acid receptor RXR | 0.0032 | 0.0217 | 0.1052 |
Echinococcus multilocularis | nuclear receptor 2DBD gamma | 0.0032 | 0.0217 | 0.0217 |
Echinococcus granulosus | dual specificity | 0.0092 | 0.1031 | 0.1031 |
Echinococcus multilocularis | musashi | 0.0053 | 0.0508 | 0.0508 |
Schistosoma mansoni | intermediate filament proteins | 0.0053 | 0.0508 | 0.2463 |
Plasmodium falciparum | histone acetyltransferase GCN5 | 0.0043 | 0.036 | 1 |
Echinococcus multilocularis | Basic leucine zipper (bZIP) transcription | 0.0148 | 0.1791 | 0.1791 |
Loa Loa (eye worm) | hypothetical protein | 0.0025 | 0.0119 | 0.0119 |
Leishmania major | serine/threonine-protein kinase, putative,protein kinase, putative | 0.0092 | 0.1031 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0017 | 0.0012 | 0.0012 |
Trichomonas vaginalis | bromodomain-containing protein, putative | 0.0046 | 0.0413 | 1 |
Trypanosoma cruzi | CMGC/DYRK protein kinase, putative | 0.0092 | 0.1031 | 1 |
Schistosoma mansoni | transcription factor LCR-F1 | 0.0148 | 0.1791 | 0.8677 |
Echinococcus granulosus | DNA apurinic or apyrimidinic site lyase | 0.0019 | 0.0035 | 0.0035 |
Brugia malayi | hypothetical protein | 0.0148 | 0.1791 | 0.1791 |
Loa Loa (eye worm) | hypothetical protein | 0.0289 | 0.3711 | 0.3711 |
Onchocerca volvulus | Huntingtin homolog | 0.0255 | 0.3245 | 1 |
Schistosoma mansoni | Tr4/Tr2 (homologue) | 0.0032 | 0.0217 | 0.1052 |
Loa Loa (eye worm) | intermediate filament tail domain-containing protein | 0.0053 | 0.0508 | 0.0508 |
Loa Loa (eye worm) | hypothetical protein | 0.0017 | 0.0012 | 0.0012 |
Loa Loa (eye worm) | hypothetical protein | 0.0255 | 0.3245 | 0.3245 |
Echinococcus granulosus | histone acetyltransferase KAT2B | 0.0046 | 0.0413 | 0.0413 |
Echinococcus multilocularis | gcn5proteinral control of amino acid synthesis | 0.0158 | 0.1927 | 0.1927 |
Loa Loa (eye worm) | hypothetical protein | 0.0032 | 0.0217 | 0.0217 |
Mycobacterium ulcerans | beta-lactamase | 0.0036 | 0.0267 | 0.8283 |
Trypanosoma brucei | hypothetical protein, conserved | 0.0036 | 0.0267 | 0.2325 |
Schistosoma mansoni | thyroid hormone receptor | 0.0032 | 0.0217 | 0.1052 |
Loa Loa (eye worm) | GTP-binding regulatory protein Gs alpha-S chain | 0.0095 | 0.1075 | 0.1075 |
Echinococcus granulosus | nuclear receptor 2DBD gamma | 0.0032 | 0.0217 | 0.0217 |
Loa Loa (eye worm) | hypothetical protein | 0.0032 | 0.0217 | 0.0217 |
Mycobacterium leprae | conserved hypothetical protein | 0.0036 | 0.0267 | 0.5 |
Echinococcus multilocularis | COUP TF:Svp nuclear hormone receptor | 0.0032 | 0.0217 | 0.0217 |
Treponema pallidum | exodeoxyribonuclease (exoA) | 0.0019 | 0.0035 | 0.5 |
Echinococcus multilocularis | serotonin receptor | 0.0161 | 0.1977 | 0.1977 |
Loa Loa (eye worm) | hypothetical protein | 0.0161 | 0.1977 | 0.1977 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0095 | 0.1075 | 0.1075 |
Echinococcus multilocularis | DNA (apurinic or apyrimidinic site) lyase | 0.0019 | 0.0035 | 0.0035 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-14 | 0.0032 | 0.0217 | 0.0217 |
Brugia malayi | Ligand-binding domain of nuclear hormone receptor family protein | 0.0032 | 0.0217 | 0.0217 |
Schistosoma mansoni | hypothetical protein | 0.0148 | 0.1791 | 0.8677 |
Loa Loa (eye worm) | beta-LACTamase domain containing family member | 0.0036 | 0.0267 | 0.0267 |
Loa Loa (eye worm) | hypothetical protein | 0.0032 | 0.0217 | 0.0217 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-1 | 0.0032 | 0.0217 | 0.0217 |
Loa Loa (eye worm) | hypothetical protein | 0.0036 | 0.0267 | 0.0267 |
Brugia malayi | Intermediate filament tail domain containing protein | 0.0053 | 0.0508 | 0.0508 |
Loa Loa (eye worm) | hypoxia-induced factor 1 | 0.0164 | 0.201 | 0.201 |
Trichomonas vaginalis | D-aminoacylase, putative | 0.0036 | 0.0267 | 0.6134 |
Brugia malayi | hypothetical protein | 0.0017 | 0.0012 | 0.0012 |
Echinococcus granulosus | beta LACTamase domain containing family member | 0.0036 | 0.0267 | 0.0267 |
Loa Loa (eye worm) | MH2 domain-containing protein | 0.0235 | 0.2983 | 0.2983 |
Echinococcus granulosus | FTZ F1 nuclear receptor protein | 0.0032 | 0.0217 | 0.0217 |
Brugia malayi | Ligand-binding domain of nuclear hormone receptor family protein | 0.0032 | 0.0217 | 0.0217 |
Schistosoma mansoni | serine/threonine protein kinase | 0.0092 | 0.1031 | 0.4997 |
Entamoeba histolytica | hypothetical protein | 0.0148 | 0.1791 | 1 |
Brugia malayi | Nuclear hormone receptor family member nhr-40 | 0.0032 | 0.0217 | 0.0217 |
Loa Loa (eye worm) | hypothetical protein | 0.0091 | 0.1025 | 0.1025 |
Schistosoma mansoni | thyroid hormone receptor | 0.0032 | 0.0217 | 0.1052 |
Onchocerca volvulus | Huntingtin homolog | 0.0255 | 0.3245 | 1 |
Onchocerca volvulus | 0.0053 | 0.0508 | 0.0961 | |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0095 | 0.1075 | 0.5208 |
Loa Loa (eye worm) | hypothetical protein | 0.0255 | 0.3245 | 0.3245 |
Brugia malayi | hypoxia-induced factor 1 | 0.0164 | 0.201 | 0.201 |
Echinococcus multilocularis | survival motor neuron protein 1 | 0.0751 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0026 | 0.0132 | 0.0132 |
Echinococcus multilocularis | dual specificity | 0.0092 | 0.1031 | 0.1031 |
Brugia malayi | Nuclear hormone receptor-like 1 | 0.0032 | 0.0217 | 0.0217 |
Leishmania major | hypothetical protein, conserved | 0.0036 | 0.0267 | 0.2325 |
Brugia malayi | steroid hormone receptor | 0.0032 | 0.0217 | 0.0217 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0095 | 0.1075 | 0.1075 |
Loa Loa (eye worm) | hypothetical protein | 0.0052 | 0.0495 | 0.0495 |
Loa Loa (eye worm) | hypothetical protein | 0.0032 | 0.0217 | 0.0217 |
Trypanosoma cruzi | CMGC/DYRK protein kinase, putative | 0.0092 | 0.1031 | 1 |
Mycobacterium tuberculosis | Conserved protein | 0.0036 | 0.0267 | 0.0814 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0095 | 0.1075 | 0.1075 |
Onchocerca volvulus | 0.0036 | 0.0267 | 0.0164 | |
Schistosoma mansoni | nuclear hormone receptor nor-1/nor-2 | 0.0032 | 0.0217 | 0.1052 |
Brugia malayi | Nuclear hormone receptor-like 1 | 0.0017 | 0.0012 | 0.0012 |
Loa Loa (eye worm) | nuclear Hormone Receptor family member | 0.0032 | 0.0217 | 0.0217 |
Loa Loa (eye worm) | hypothetical protein | 0.0178 | 0.2197 | 0.2197 |
Entamoeba histolytica | acetyltransferase, GNAT family | 0.0043 | 0.036 | 0.1851 |
Schistosoma mansoni | nuclear hormone receptor | 0.0032 | 0.0217 | 0.1052 |
Onchocerca volvulus | 0.0036 | 0.0267 | 0.0164 | |
Echinococcus granulosus | nuclear receptor subfamily 1 group D | 0.0017 | 0.0012 | 0.0012 |
Schistosoma mansoni | hypothetical protein | 0.0168 | 0.2064 | 1 |
Echinococcus multilocularis | thyroid hormone receptor alpha | 0.0032 | 0.0217 | 0.0217 |
Brugia malayi | Nuclear hormone receptor family member nhr-19 | 0.0032 | 0.0217 | 0.0217 |
Toxoplasma gondii | histone lysine acetyltransferase GCN5-B | 0.0046 | 0.0413 | 1 |
Echinococcus multilocularis | lamin | 0.0053 | 0.0508 | 0.0508 |
Activity type | Activity value | Assay description | Source | Reference |
---|---|---|---|---|
Agonist effect (functional) | = 42 % | Agonist effect for Dopamine D4.2 receptor of the compound determined as rate of incorporation of [3H]- thymidine relative to quinpirole | ChEMBL. | 11549463 |
EC50 (functional) | = 31 nM | Agonist effect on the Dopamine D4.2 receptor was determined by evaluating effective concentration causing stimulation of mitogenesis | ChEMBL. | 11549463 |
Ki (binding) | 0 nM | In vitro for its ability to displace [3H]- SCH 23390 from Dopamine receptor D1 in bovine striatal membrane expressed in CHO cells; Not determined | ChEMBL. | 11549463 |
Ki (binding) | = 0.95 nM | In vitro for its ability to displace [3H]- spiperone from cloned human Dopamine receptor D4 expressed in CHO cells; High binding affinity | ChEMBL. | 11549463 |
Ki (binding) | = 45 nM | In vitro for its ability to displace [3H]-8-OH-DPAT from 5-hydroxytryptamine 1A receptor in porcine brain homogenate | ChEMBL. | 11549463 |
Ki (binding) | = 51 nM | In vitro for its ability to displace [3H]- spiperone from cloned human Dopamine receptor D4 expressed in CHO cells; Low binding affinity | ChEMBL. | 11549463 |
Ki (binding) | = 72 nM | In vitro for its ability to displace [3H]- spiperone from cloned human Dopamine receptor D4 expressed in CHO cells | ChEMBL. | 11549463 |
Ki (binding) | = 870 nM | In vitro for its ability to displace [3H]- ketanserin from 5-hydroxytryptamine 2 receptor in porcine brain homogenate | ChEMBL. | 11549463 |
Ki (binding) | = 7100 nM | Displacement of [3H]-spiperone from human Dopamine receptor D3 expressed in CHO cells | ChEMBL. | 11549463 |
Ki (binding) | = 9000 nM | Displacement of [3H]-spiperone from human Dopamine receptor D3 expressed in CHO cells | ChEMBL. | 11549463 |
Ki (binding) | = 10000 nM | In vitro for its ability to displace [3H]- spiperone from cloned human dopamine D2 short receptor expressed in CHO cells | ChEMBL. | 11549463 |
Ki (binding) | = 10000 nM | In vitro for its ability to displace [3H]- spiperone from cloned human Dopamine receptor D2L expressed in CHO cells | ChEMBL. | 11549463 |
Ki (binding) | = 11000 nM | In vitro for its ability to displace [3H]- spiperone from cloned human dopamine D2 short receptor expressed in CHO cells | ChEMBL. | 11549463 |
Ki (binding) | = 12000 nM | In vitro for its ability to displace [3H]- SCH 23390 from Dopamine receptor D1 in bovine striatal membrane expressed in CHO cells | ChEMBL. | 11549463 |
Ki (binding) | = 14000 nM | In vitro for its ability to displace [3H]- spiperone from cloned human dopamine D2 long receptor expressed in CHO cells | ChEMBL. | 11549463 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.
1 literature reference was collected for this gene.