Detailed information for compound 1407177

Basic information

Technical information
  • TDR Targets ID: 1407177
  • Name: 2-[3-[(2-chlorophenyl)methyl]-6,7-dimethoxy-2 ,4-dioxoquinazolin-1-yl]-N-(4-methoxyphenyl)a cetamide
  • MW: 509.938 | Formula: C26H24ClN3O6
  • H donors: 1 H acceptors: 3 LogP: 3.75 Rotable bonds: 9
    Rule of 5 violations (Lipinski): 2
  • SMILES: COc1cc2c(cc1OC)c(=O)n(c(=O)n2CC(=O)Nc1ccc(cc1)OC)Cc1ccccc1Cl
  • InChi: 1S/C26H24ClN3O6/c1-34-18-10-8-17(9-11-18)28-24(31)15-29-21-13-23(36-3)22(35-2)12-19(21)25(32)30(26(29)33)14-16-6-4-5-7-20(16)27/h4-13H,14-15H2,1-3H3,(H,28,31)
  • InChiKey: UNRVKPBNVYZVHN-UHFFFAOYSA-N  

Network

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Synonyms

  • 2-[3-[(2-chlorophenyl)methyl]-6,7-dimethoxy-2,4-dioxo-quinazolin-1-yl]-N-(4-methoxyphenyl)acetamide
  • 2-[3-[(2-chlorophenyl)methyl]-6,7-dimethoxy-2,4-dioxo-1-quinazolinyl]-N-(4-methoxyphenyl)acetamide
  • 2-[3-(2-chlorobenzyl)-2,4-diketo-6,7-dimethoxy-quinazolin-1-yl]-N-(4-methoxyphenyl)acetamide
  • 2-[3-[(2-chlorophenyl)methyl]-6,7-dimethoxy-2,4-dioxo-quinazolin-1-yl]-N-(4-methoxyphenyl)ethanamide
  • NCGC00106829-01
  • C260-3023

Targets

Known targets for this compound

Species Target name Source Bibliographic reference
Homo sapiens apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3D Starlite/ChEMBL No references
Rattus norvegicus Inositol monophosphatase 1 Starlite/ChEMBL No references

Predicted pathogen targets for this compound

By orthology
Species Potential target Known druggable target/s Ortholog Group
Trichomonas vaginalis inositol monophosphatase, putative Get druggable targets OG5_126810 All targets in OG5_126810
Brugia malayi Inositol-1 Get druggable targets OG5_126810 All targets in OG5_126810
Wolbachia endosymbiont of Brugia malayi fructose-1,6-bisphosphatase Get druggable targets OG5_126810 All targets in OG5_126810
Trichomonas vaginalis myo inositol monophosphatase, putative Get druggable targets OG5_126810 All targets in OG5_126810
Toxoplasma gondii inositol(myo)-1(or 4)-monophosphatase 2, putative Get druggable targets OG5_126810 All targets in OG5_126810
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative Get druggable targets OG5_126810 All targets in OG5_126810
Leishmania mexicana myo-inositol-1(or 4)-monophosphatase 1, putative Get druggable targets OG5_126810 All targets in OG5_126810
Trypanosoma brucei gambiense inositol-1(or 4)-monophosphatase 1, putative Get druggable targets OG5_126810 All targets in OG5_126810
Leishmania major myo-inositol-1(or 4)-monophosphatase 1, putative Get druggable targets OG5_126810 All targets in OG5_126810
Mycobacterium ulcerans extragenic suppressor protein SuhB Get druggable targets OG5_126810 All targets in OG5_126810
Echinococcus multilocularis inositol monophosphatase 1 Get druggable targets OG5_126810 All targets in OG5_126810
Neospora caninum hypothetical protein Get druggable targets OG5_126810 All targets in OG5_126810
Leishmania donovani myo-inositol-1(or 4)-monophosphatase 1, putative Get druggable targets OG5_126810 All targets in OG5_126810
Trypanosoma congolense inositol-1(or 4)-monophosphatase 1, putative Get druggable targets OG5_126810 All targets in OG5_126810
Mycobacterium tuberculosis Inositol-1-monophosphatase SuhB Get druggable targets OG5_126810 All targets in OG5_126810
Schistosoma japonicum ko:K01092 myo-inositol-1(or 4)-monophosphatase [EC3.1.3.25], putative Get druggable targets OG5_126810 All targets in OG5_126810
Schistosoma mansoni inositol monophosphatase Get druggable targets OG5_126810 All targets in OG5_126810
Leishmania infantum myo-inositol-1(or 4)-monophosphatase 1, putative Get druggable targets OG5_126810 All targets in OG5_126810
Trypanosoma brucei inositol-1(or 4)-monophosphatase 1, putative Get druggable targets OG5_126810 All targets in OG5_126810
Mycobacterium leprae possible inositol monophosphatase SubH (IMPase) (inositol-1-phosphatase) (I-1-Pase ). Get druggable targets OG5_126810 All targets in OG5_126810
Trichomonas vaginalis myo inositol monophosphatase, putative Get druggable targets OG5_126810 All targets in OG5_126810
Echinococcus granulosus inositol monophosphatase 1 Get druggable targets OG5_126810 All targets in OG5_126810
Leishmania braziliensis myo-inositol-1(or 4)-monophosphatase 1, putative Get druggable targets OG5_126810 All targets in OG5_126810
Loa Loa (eye worm) inositol-1 Get druggable targets OG5_126810 All targets in OG5_126810
Schistosoma mansoni inositol monophosphatase Get druggable targets OG5_126810 All targets in OG5_126810
Entamoeba histolytica myo-inositol monophosphatase, putative Get druggable targets OG5_126810 All targets in OG5_126810
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative Get druggable targets OG5_126810 All targets in OG5_126810

By sequence similarity to non orthologous known druggable targets
Species Potential target Known druggable target Length Alignment span Identity
Trichomonas vaginalis myo inositol monophosphatase, putative Inositol monophosphatase 1   277 aa 276 aa 21.4 %
Onchocerca volvulus Putative trans-2-enoyl-CoA reductase 1, mitochondrial Inositol monophosphatase 1   277 aa 278 aa 23.0 %
Candida albicans one of two closely related genes similar to S. cerevisiae MET22/HAL2 (YOL064C) bisphosphate-3'-nucleotidase, implicated in salt Inositol monophosphatase 1   277 aa 307 aa 22.5 %
Dictyostelium discoideum 3',5'-bisphosphate nucleotidase Inositol monophosphatase 1   277 aa 230 aa 25.2 %
Trypanosoma cruzi myo-inositol-1 phosphatase, putative Inositol monophosphatase 1   277 aa 284 aa 30.6 %
Trypanosoma brucei gambiense inositol-1(or 4)-monophosphatase, putative Inositol monophosphatase 1   277 aa 309 aa 27.8 %
Schistosoma japonicum ko:K01082 3'(2'), 5'-bisphosphate nucleotidase [EC3.1.3.7], putative Inositol monophosphatase 1   277 aa 275 aa 21.5 %
Entamoeba histolytica 3(2),5-bisphosphate nucleotidase, putative Inositol monophosphatase 1   277 aa 263 aa 24.0 %
Trichomonas vaginalis diphosphonucleoside phosphohydrolase, putative Inositol monophosphatase 1   277 aa 263 aa 21.7 %
Schistosoma mansoni pap-inositol-14-phosphatase Inositol monophosphatase 1   277 aa 279 aa 22.9 %
Onchocerca volvulus Inositol monophosphatase 1   277 aa 238 aa 22.7 %
Trypanosoma brucei inositol-1(or 4)-monophosphatase, putative Inositol monophosphatase 1   277 aa 304 aa 27.3 %
Entamoeba histolytica 3(2),5-bisphosphate nucleotidase, putative Inositol monophosphatase 1   277 aa 287 aa 22.3 %
Loa Loa (eye worm) hypothetical protein Inositol monophosphatase 1   277 aa 298 aa 23.8 %
Onchocerca volvulus Putative 28S ribosomal protein S10, mitochondrial Inositol monophosphatase 1   277 aa 271 aa 46.1 %
Brugia malayi Inositol monophosphatase family protein Inositol monophosphatase 1   277 aa 238 aa 21.8 %
Dictyostelium discoideum 3',5'-bisphosphate nucleotidase 1 Inositol monophosphatase 1   277 aa 275 aa 22.2 %
Trypanosoma cruzi inositol polyphosphate 1-phosphatase, putative Inositol monophosphatase 1   277 aa 291 aa 23.7 %
Candida albicans one of two closely related genes similar to S. cerevisiae MET22/HAL2 (YOL064C) bisphosphate-3'-nucleotidase, implicated in salt Inositol monophosphatase 1   277 aa 306 aa 22.5 %
Trypanosoma congolense inositol-1(or 4)-monophosphatase, putative Inositol monophosphatase 1   277 aa 304 aa 28.9 %
Trichomonas vaginalis inositol monophosphatase, putative Inositol monophosphatase 1   277 aa 268 aa 22.4 %
Candida albicans one of two closely related genes similar to S. cerevisiae MET22/HAL2 (YOL064C) bisphosphate-3'-nucleotidase, implicated in salt Inositol monophosphatase 1   277 aa 300 aa 22.0 %
Trichomonas vaginalis inositol monophosphatase, putative Inositol monophosphatase 1   277 aa 258 aa 21.7 %

Obtained from network model

Ranking Plot


Putative Targets List


Species Potential target Raw Global Species
Leishmania major p-glycoprotein 0.0021 0.0013 0.0025
Trypanosoma brucei target of rapamycin kinase 3, putative 0.0073 0.0171 0.0342
Giardia lamblia Gamma tubulin 0.0941 0.2836 0.5679
Trypanosoma cruzi hydroxyacylglutathione hydrolase, putative 0.003 0.004 0.0081
Trypanosoma cruzi glyoxalase II 0.003 0.004 0.0081
Schistosoma mansoni multidrug resistance protein 0.0021 0.0013 0.002
Loa Loa (eye worm) hydroxyacylglutathione hydrolase 0.003 0.004 0.0058
Echinococcus granulosus Tubulin alpha 1 chain 0.1261 0.3818 0.6024
Brugia malayi bZIP transcription factor family protein 0.0264 0.0758 0.1097
Loa Loa (eye worm) hypothetical protein 0.0034 0.0052 0.0075
Echinococcus multilocularis cpg binding protein 0.0095 0.0238 0.0238
Schistosoma mansoni Smad4 0.0019 0.0005 0.0007
Toxoplasma gondii inositol(myo)-1(or 4)-monophosphatase 2, putative 0.0045 0.0084 0.0168
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.006 0.013 0.0206
Echinococcus multilocularis L aminoadipate semialdehyde 0.0093 0.0233 0.0233
Wolbachia endosymbiont of Brugia malayi 4'-phosphopantetheinyl transferase 0.0026 0.0027 0.0185
Loa Loa (eye worm) hypothetical protein 0.0026 0.0026 0.0037
Onchocerca volvulus Putative organic anion transporter 0.0085 0.0208 0.0923
Trichomonas vaginalis CMGC family protein kinase 0.0103 0.0262 0.0524
Trichomonas vaginalis PIKK family atypical protein kinase 0.0049 0.0098 0.0197
Brugia malayi Raf kinase 0.0044 0.0082 0.0119
Mycobacterium ulcerans cytochrome P450 136A2 Cyp136A2 0.0018 0.0003 0.0026
Brugia malayi jmjC domain containing protein 0.0059 0.0127 0.0184
Echinococcus multilocularis mitogen activated protein kinase 0.0103 0.0262 0.0262
Echinococcus multilocularis Tubulin beta 2C chain 0.1643 0.499 0.499
Trichomonas vaginalis tubulin alpha chain, putative 0.1643 0.499 1
Leishmania major beta tubulin 0.1643 0.499 1
Brugia malayi sodium-independent organic anion transporter family protein 0.0085 0.0208 0.0301
Loa Loa (eye worm) hypothetical protein 0.0026 0.0026 0.0037
Brugia malayi hypothetical protein 0.0149 0.0405 0.0586
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0103 0.0262 0.0524
Loa Loa (eye worm) hypothetical protein 0.0026 0.0026 0.0037
Echinococcus multilocularis tubulin alpha chain 0.1261 0.3818 0.3818
Echinococcus granulosus Nuclear hormone receptor HR96 0.0026 0.0026 0.0041
Mycobacterium tuberculosis Probable fructose-bisphosphate aldolase Fba 0.016 0.0437 0.2592
Mycobacterium tuberculosis Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) 0.0019 0.0005 0.0012
Trichomonas vaginalis beta lactamase domain, putative 0.003 0.004 0.0081
Trichomonas vaginalis adenylate and guanylate cyclases, putative 0.0051 0.0104 0.0208
Loa Loa (eye worm) tubulin beta chain 0.1643 0.499 0.7219
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0186 0.0518 0.0518
Loa Loa (eye worm) cytochrome P450 family protein 0.0055 0.0115 0.0166
Leishmania major mitogen activated protein kinase, putative,map kinase, putative 0.0103 0.0262 0.0524
Schistosoma mansoni zinc finger protein 0.0026 0.0026 0.0041
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0327 0.0951 0.1906
Plasmodium vivax multidrug resistance protein 1, putative 0.0021 0.0013 0.0025
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase domain containing protein 0.0037 0.006 0.0121
Plasmodium falciparum ATP-dependent DNA helicase Q1 0.0029 0.0035 0.007
Mycobacterium tuberculosis Probable isocitrate dehydrogenase [NADP] Icd1 (oxalosuccinate decarboxylase) (IDH) (NADP+-specific ICDH) (IDP) 0.0032 0.0044 0.0245
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0096 0.0243 0.0383
Loa Loa (eye worm) tubulin alpha-2 chain 0.1261 0.3818 0.5524
Schistosoma mansoni tubulin subunit beta 0.1643 0.499 0.7872
Echinococcus granulosus survival motor neuron protein 1 0.0236 0.0671 0.1059
Trichomonas vaginalis tubulin beta-1 chain, putative 0.0411 0.1209 0.2423
Entamoeba histolytica phosphofructokinase, putative 0.0111 0.0288 0.0577
Schistosoma mansoni jumonji domain containing protein 0.0059 0.0127 0.0201
Echinococcus granulosus cpg binding protein 0.0095 0.0238 0.0375
Onchocerca volvulus 0.0085 0.0208 0.0923
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0088 0.0218 0.0344
Entamoeba histolytica tubulin alpha chain, putative 0.1261 0.3818 0.7652
Echinococcus multilocularis protein patched 0.0085 0.0207 0.0207
Echinococcus multilocularis musashi 0.0082 0.0197 0.0197
Loa Loa (eye worm) hypothetical protein 0.006 0.013 0.0189
Entamoeba histolytica phosphofructokinase, putative 0.0111 0.0288 0.0577
Schistosoma mansoni tubulin subunit beta 0.1643 0.499 0.7872
Loa Loa (eye worm) alpha-tubulin 0.1261 0.3818 0.5524
Echinococcus multilocularis beta tubulin 0.1643 0.499 0.499
Echinococcus multilocularis tumor protein p63 0.1025 0.3093 0.3093
Loa Loa (eye worm) hypothetical protein 0.0029 0.0035 0.0051
Giardia lamblia Ubiquitin carboxyl-terminal hydrolase 4 0.0037 0.006 0.0111
Echinococcus multilocularis metallo beta lactamase domain containing protein 0.003 0.004 0.004
Chlamydia trachomatis ribonuclease Z 0.003 0.004 0.1612
Toxoplasma gondii alpha tubulin TUBA1 0.1261 0.3818 0.7652
Trypanosoma cruzi cytochrome P450, putative 0.0055 0.0115 0.023
Trichomonas vaginalis ABC transporter, putative 0.0021 0.0013 0.0025
Leishmania major beta tubulin 0.1643 0.499 1
Giardia lamblia Delta tubulin 0.0411 0.1209 0.2415
Echinococcus multilocularis thyroid hormone receptor alpha 0.006 0.013 0.013
Trichomonas vaginalis ABC transporter, half transporter, putative 0.0021 0.0013 0.0025
Echinococcus granulosus lipoxygenase domain containing protein 0.0139 0.0373 0.0588
Loa Loa (eye worm) CBP-B 0.0069 0.0158 0.0228
Trichomonas vaginalis helicase, putative 0.002 0.0009 0.0019
Trypanosoma brucei alpha tubulin 0.1261 0.3818 0.7652
Trichomonas vaginalis tubulin alpha chain, putative 0.0503 0.149 0.2986
Echinococcus multilocularis expressed protein 0.075 0.2249 0.2249
Brugia malayi beta-lactamase family protein 0.0088 0.0218 0.0315
Trypanosoma brucei ATP-dependent DEAD/H DNA helicase recQ, putative 0.0031 0.0043 0.0086
Toxoplasma gondii protease inhibitor PI2 0.0058 0.0125 0.0251
Echinococcus granulosus jun protein 0.0264 0.0758 0.1196
Leishmania major alpha tubulin 0.1261 0.3818 0.7652
Giardia lamblia Beta tubulin 0.1643 0.499 1
Schistosoma mansoni nuclear hormone receptor 0.006 0.013 0.0206
Echinococcus granulosus Tubulin beta 2C chain 0.1643 0.499 0.7872
Loa Loa (eye worm) hypothetical protein 0.0386 0.113 0.1635
Mycobacterium ulcerans hypothetical protein 0.003 0.004 0.0333
Trypanosoma brucei phosphatidylinositol 3-kinase, putative 0.0031 0.0041 0.0083
Schistosoma mansoni rab6-interacting 0.0139 0.0373 0.0588
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0037 0.006 0.0121
Trypanosoma brucei mitogen activated protein kinase 4, putative 0.0103 0.0262 0.0524
Mycobacterium leprae conserved hypothetical protein 0.003 0.004 0.0307
Loa Loa (eye worm) hypothetical protein 0.0046 0.0089 0.0129
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.0019 0.0005 0.0007
Mycobacterium leprae cell division protein FtsZ 0.0411 0.1209 1
Brugia malayi Cytochrome P450 family protein 0.0018 0.0003 0.0005
Toxoplasma gondii alpha-tubulin I, putative 0.1261 0.3818 0.7652
Loa Loa (eye worm) multidrug resistance protein 3 0.0021 0.0013 0.0018
Trichomonas vaginalis phosphofructokinase, putative 0.0111 0.0288 0.0577
Schistosoma mansoni serine/threonine protein kinase 0.0103 0.0262 0.0413
Trypanosoma brucei dihydrolipoamide dehydrogenase, point mutation 0.0033 0.0049 0.0097
Echinococcus multilocularis beta adrenergic receptor kinase 0.0044 0.0082 0.0082
Giardia lamblia Fructose-bisphosphate aldolase 0.0327 0.0951 0.1897
Wolbachia endosymbiont of Brugia malayi fructose-1,6-bisphosphatase 0.0045 0.0084 0.0655
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0096 0.0243 0.0383
Leishmania major gamma-tubulin 0.0941 0.2836 0.5683
Trichomonas vaginalis D-aminoacylase, putative 0.0088 0.0218 0.0437
Schistosoma mansoni smdr2 0.0021 0.0013 0.002
Trichomonas vaginalis CMGC family protein kinase 0.0103 0.0262 0.0524
Treponema pallidum diphosphate--fructose-6-phosphate 1-phosphotransferase 0.0111 0.0288 0.2349
Echinococcus multilocularis protein dispatched 1 0.0097 0.0244 0.0244
Loa Loa (eye worm) cytochrome P450 family protein 0.0055 0.0115 0.0166
Plasmodium falciparum apurinic/apyrimidinic endonuclease Apn1, putative 0.0077 0.0184 0.0368
Trypanosoma brucei trypanothione reductase 0.0096 0.024 0.0481
Entamoeba histolytica P-glycoprotein-5 0.0021 0.0013 0.0025
Mycobacterium tuberculosis Conserved protein 0.0088 0.0218 0.1283
Mycobacterium ulcerans cytochrome P450 187A4 Cyp187A4 0.0018 0.0003 0.0026
Trichomonas vaginalis ATP-binding cassette transporter, putative 0.0021 0.0013 0.0025
Brugia malayi Smad1 0.0042 0.0076 0.011
Entamoeba histolytica hypothetical protein 0.0043 0.008 0.0159
Toxoplasma gondii 4'-phosphopantetheinyl transferase domain-containing protein 0.0026 0.0027 0.0055
Trichomonas vaginalis multidrug resistance protein 1, 2, putative 0.0021 0.0013 0.0025
Schistosoma mansoni regulator of G protein signaling 17 19 20 (rgs17 19 20) 0.0043 0.008 0.0125
Trichomonas vaginalis ABC transporter, putative 0.0021 0.0013 0.0025
Echinococcus granulosus ATP binding cassette subfamily B MDR:TAP 0.0021 0.0013 0.002
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0033 0.0049 0.0097
Echinococcus granulosus metallo beta lactamase domain containing protein 0.003 0.004 0.0063
Trichomonas vaginalis multidrug resistance protein 1, 2, putative 0.0021 0.0013 0.0025
Echinococcus multilocularis tubulin, beta 4A class IVa 0.1643 0.499 0.499
Brugia malayi Nuclear hormone receptor family member nhr-25 0.006 0.013 0.0189
Leishmania major beta tubulin 0.1643 0.499 1
Mycobacterium ulcerans dihydrolipoamide dehydrogenase, LpdB 0.0033 0.0049 0.0402
Echinococcus granulosus lamin dm0 0.0082 0.0197 0.0311
Toxoplasma gondii cytochrome p450 superfamily protein 0.0018 0.0003 0.0006
Trichomonas vaginalis phosphofructokinase, putative 0.003 0.0039 0.0078
Mycobacterium tuberculosis Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras 0.0242 0.069 0.4102
Trypanosoma brucei phosphatidylinositol 3-related kinase, putative 0.0031 0.0041 0.0083
Trichomonas vaginalis PIKK family atypical protein kinase 0.0025 0.0022 0.0045
Leishmania major protein kinase, putative 0.0052 0.0107 0.0214
Echinococcus multilocularis mitogen activated protein kinase 3 0.0103 0.0262 0.0262
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.0082 0.0197 0.0286
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.006 0.013 0.013
Trypanosoma cruzi glyoxalase II 0.003 0.004 0.0081
Trichomonas vaginalis phosphofructokinase, putative 0.003 0.0039 0.0078
Trichomonas vaginalis guanylate cyclase, putative 0.0051 0.0104 0.0208
Schistosoma mansoni axis inhibition protein axin 0.0043 0.008 0.0125
Trichomonas vaginalis conserved hypothetical protein 0.0037 0.006 0.0121
Echinococcus granulosus A kinase anchor protein 10 mitochondrial 0.0043 0.008 0.0125
Brugia malayi orphan nuclear receptor NR2E1 0.0026 0.0026 0.0037
Loa Loa (eye worm) hypothetical protein 0.006 0.013 0.0189
Schistosoma mansoni aldehyde dehydrogenase 0.0061 0.0134 0.0212
Onchocerca volvulus 0.0082 0.0197 0.0876
Schistosoma mansoni tubulin subunit delta 0.0411 0.1209 0.1907
Echinococcus multilocularis lamin 0.0082 0.0197 0.0197
Trichomonas vaginalis lipid A export ATP-binding/permease protein msba, putative 0.0021 0.0013 0.0025
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0091 0.0226 0.0357
Trypanosoma cruzi phosphatidylinositol 3-related kinase, putative 0.0031 0.0041 0.0083
Giardia lamblia NADH oxidase lateral transfer candidate 0.0033 0.0049 0.0087
Echinococcus granulosus sterol regulatory element binding protein 0.0085 0.0207 0.0326
Trichomonas vaginalis adenylate cyclase, putative 0.0051 0.0104 0.0208
Toxoplasma gondii Kazal-type serine protease inhibitor domain-containing protein 0.0058 0.0125 0.0251
Brugia malayi hypothetical protein 0.0043 0.008 0.0115
Echinococcus multilocularis neuropeptide receptor A26 0.0931 0.2804 0.2804
Trichomonas vaginalis ATP-binding cassette transporter, putative 0.0021 0.0013 0.0025
Mycobacterium tuberculosis Probable esterase LipL 0.0088 0.0218 0.1283
Echinococcus granulosus beta tubulin 0.1643 0.499 0.7872
Loa Loa (eye worm) CMGC/MAPK/ERK1 protein kinase 0.0103 0.0262 0.0379
Trichomonas vaginalis apoptosis inducing factor, putative 0.0039 0.0067 0.0135
Loa Loa (eye worm) hypothetical protein 0.0236 0.0671 0.0971
Trichomonas vaginalis phosphofructokinase, putative 0.003 0.0039 0.0078
Echinococcus granulosus raf serine:threonine protein kinase 0.0044 0.0082 0.013
Entamoeba histolytica recQ family helicase, putative 0.0031 0.0043 0.0086
Loa Loa (eye worm) hypothetical protein 0.0023 0.0018 0.0026
Trypanosoma cruzi epsilon tubulin, putative 0.0941 0.2835 0.5681
Schistosoma mansoni nuclear receptor 0.0026 0.0026 0.0041
Schistosoma mansoni tubulin subunit alpha 0.1261 0.3818 0.6024
Echinococcus multilocularis hypothetical protein 0.1261 0.3818 0.3818
Echinococcus multilocularis lipoxygenase domain containing protein 0.0139 0.0373 0.0373
Trypanosoma brucei isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0032 0.0044 0.0089
Trichomonas vaginalis PIKK family atypical protein kinase 0.0031 0.0041 0.0083
Brugia malayi Bloom's syndrome protein homolog 0.0041 0.0074 0.0107
Trichomonas vaginalis conserved hypothetical protein 0.002 0.0009 0.0019
Mycobacterium ulcerans glyoxalase II, GloB 0.003 0.004 0.0333
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0327 0.0951 0.1906
Mycobacterium tuberculosis Probable soluble pyridine nucleotide transhydrogenase SthA (STH) (NAD(P)(+) transhydrogenase [B-specific]) (nicotinamide nucleot 0.0033 0.0049 0.0271
Loa Loa (eye worm) hypothetical protein 0.0088 0.0218 0.0315
Echinococcus granulosus axis inhibition protein axin 0.0043 0.008 0.0125
Leishmania major tyrosyl-DNA phosphodiesterase 1 0.0066 0.0149 0.0299
Echinococcus multilocularis ubiquitin specific protease 41 0.0037 0.006 0.006
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 8 0.0037 0.006 0.006
Echinococcus multilocularis tubulin alpha chain 0.1261 0.3818 0.3818
Trichomonas vaginalis penicillin-binding protein, putative 0.0088 0.0218 0.0437
Loa Loa (eye worm) hypothetical protein 0.0058 0.0125 0.0181
Trichomonas vaginalis PIKK family atypical protein kinase 0.0091 0.0228 0.0457
Trichomonas vaginalis PIKK family atypical protein kinase 0.0068 0.0156 0.0312
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0026 0.0026 0.0041
Mycobacterium ulcerans putative regulatory protein 0.0145 0.0393 0.3254
Schistosoma mansoni ecdysone-induced protein 78c (dr-78) 0.0034 0.0052 0.0081
Brugia malayi bHLH-PAS transcription factor 0.0145 0.0393 0.0569
Echinococcus multilocularis tyrosyl DNA phosphodiesterase 1 0.0066 0.0149 0.0149
Trichomonas vaginalis PIKK family atypical protein kinase 0.0031 0.0041 0.0083
Brugia malayi hypothetical protein 0.0034 0.0052 0.0075
Brugia malayi nuclear hormone receptor family member nhr-6 0.0026 0.0026 0.0037
Plasmodium falciparum glutathione reductase 0.0033 0.0049 0.0097
Onchocerca volvulus 0.0088 0.0218 0.0968
Echinococcus granulosus Nuclear hormone receptor HR96 0.0026 0.0026 0.0041
Loa Loa (eye worm) hypothetical protein 0.0026 0.0026 0.0037
Schistosoma mansoni TGF-beta signal transducer Smad2 0.0042 0.0076 0.012
Echinococcus multilocularis axis inhibition protein axin 0.0043 0.008 0.008
Mycobacterium tuberculosis Probable 6-phosphofructokinase PfkA (phosphohexokinase) (phosphofructokinase) 0.0111 0.0288 0.1699
Entamoeba histolytica hypothetical protein 0.0043 0.008 0.0159
Echinococcus multilocularis beta tubulin 0.1643 0.499 0.499
Mycobacterium ulcerans cytochrome P450 123A3 Cyp123A3 0.0018 0.0003 0.0026
Schistosoma mansoni tubulin subunit alpha 0.1261 0.3818 0.6024
Brugia malayi Inositol-1 0.0045 0.0084 0.0121
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.006 0.013 0.0206
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.006 0.013 0.0206
Leishmania major zeta tubulin, putative 0.0694 0.2077 0.4163
Mycobacterium tuberculosis Probable membrane NADH dehydrogenase NdhA 0.0218 0.0616 0.3656
Trypanosoma brucei FAT domain/Rapamycin binding domain/Phosphatidylinositol 3- and 4-kinase, putative 0.0038 0.0064 0.0128
Schistosoma mansoni blooms syndrome DNA helicase 0.0027 0.0029 0.0045
Toxoplasma gondii phosphofructokinase domain-containing protein 0.003 0.0039 0.0078
Echinococcus multilocularis transcription factor Dp 1 0.0038 0.0064 0.0064
Loa Loa (eye worm) hypothetical protein 0.0085 0.0208 0.0301
Schistosoma mansoni polycystin 1-related 0.0139 0.0373 0.0588
Trichomonas vaginalis PIKK family atypical protein kinase 0.0091 0.0228 0.0457
Mycobacterium tuberculosis Possible penicillin-binding protein 0.0564 0.1678 1
Loa Loa (eye worm) hypothetical protein 0.0088 0.0218 0.0315
Leishmania major delta tubulin, putative 0.058 0.1728 0.3464
Trichomonas vaginalis lipid A export ATP-binding/permease protein msba, putative 0.0021 0.0013 0.0025
Echinococcus granulosus aryl hydrocarbon receptor 0.0051 0.0104 0.0164
Echinococcus multilocularis ATP binding cassette subfamily B (MDR:TAP) 0.0021 0.0013 0.0013
Echinococcus granulosus L aminoadipate semialdehyde 0.0093 0.0233 0.0367
Brugia malayi Thioredoxin reductase 0.0096 0.024 0.0347
Echinococcus multilocularis 6 phosphofructokinase 0.0111 0.0288 0.0288
Onchocerca volvulus Hydroxyacylglutathione hydrolase, mitochondrial homolog 0.003 0.004 0.0179
Leishmania major acetoin dehydrogenase e3 component-like protein 0.0033 0.0049 0.0097
Loa Loa (eye worm) alpha-tubulin isotype 2 0.085 0.2556 0.3698
Brugia malayi Nuclear hormone receptor-like 1 0.0034 0.0052 0.0075
Entamoeba histolytica tubulin family protein 0.1643 0.499 1
Onchocerca volvulus 0.006 0.013 0.0579
Schistosoma mansoni hypothetical protein 0.0082 0.0198 0.0312
Schistosoma mansoni cpg binding protein 0.009 0.0222 0.0351
Echinococcus multilocularis expressed protein 0.0058 0.0125 0.0125
Echinococcus granulosus alpha tubulin 0.1261 0.3818 0.6024
Trypanosoma brucei Lanosterol 14-alpha demethylase 0.0018 0.0003 0.0006
Loa Loa (eye worm) hypothetical protein 0.0085 0.0208 0.0301
Echinococcus granulosus mothers against decapentaplegic 2 0.0019 0.0005 0.0007
Mycobacterium tuberculosis Conserved protein 0.003 0.004 0.0221
Onchocerca volvulus Mothers against decapentaplegic homolog 0.0019 0.0005 0.002
Echinococcus multilocularis Tubulin beta 2C chain 0.1643 0.499 0.499
Trichomonas vaginalis tubulin epsilon chain, putative 0.1643 0.499 1
Echinococcus multilocularis mothers against decapentaplegic 2 0.0019 0.0005 0.0005
Entamoeba histolytica phosphofructokinase, putative 0.0111 0.0288 0.0577
Brugia malayi hypothetical protein 0.0034 0.0052 0.0075
Trypanosoma cruzi beta tubulin, putative 0.1643 0.499 1
Mycobacterium ulcerans beta-lactamase 0.0088 0.0218 0.1803
Loa Loa (eye worm) MH2 domain-containing protein 0.0042 0.0076 0.011
Brugia malayi Nuclear hormone receptor family member nhr-1 0.006 0.013 0.0189
Schistosoma mansoni smad1 5 8 and 0.0042 0.0076 0.012
Plasmodium vivax hypothetical protein, conserved 0.0088 0.0218 0.0437
Giardia lamblia Sgs1 DNA helicase, putative 0.0029 0.0035 0.006
Schistosoma mansoni nuclear hormone receptor 0.0026 0.0026 0.0041
Giardia lamblia Epsilon tubulin 0.0438 0.1292 0.2581
Mycobacterium leprae possible inositol monophosphatase SubH (IMPase) (inositol-1-phosphatase) (I-1-Pase ). 0.004 0.007 0.0551
Loa Loa (eye worm) hypothetical protein 0.0085 0.0208 0.0301
Leishmania major phosphatidylinositol 3-kinase, putative 0.0031 0.0041 0.0083
Onchocerca volvulus Putative hydrolase PNKD 0.003 0.004 0.0179
Leishmania major beta tubulin 0.1643 0.499 1
Trichomonas vaginalis soluble guanylate cyclase gcy, putative 0.0051 0.0104 0.0208
Echinococcus multilocularis isocitrate dehydrogenase 0.0032 0.0044 0.0044
Leishmania major myo-inositol-1(or 4)-monophosphatase 1, putative 0.0045 0.0084 0.0168
Trypanosoma cruzi STE/STE11 serine/threonine-protein kinase, putative 0.0052 0.0107 0.0214
Echinococcus granulosus mitogen activated protein kinase 3 0.0103 0.0262 0.0413
Schistosoma mansoni organic anion transporter 0.0085 0.0208 0.0328
Loa Loa (eye worm) hypothetical protein 0.0096 0.0243 0.0351
Echinococcus granulosus nuclear receptor 2DBD gamma 0.006 0.013 0.0206
Loa Loa (eye worm) hypothetical protein 0.006 0.013 0.0189
Trichomonas vaginalis glutathione reductase, putative 0.0033 0.0049 0.0097
Schistosoma mansoni coup transcription factor 0.006 0.013 0.0206
Giardia lamblia GTOR 0.0091 0.0228 0.0447
Echinococcus granulosus TGF beta signal transducer SmadC 0.0042 0.0076 0.012
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0096 0.0243 0.0383
Entamoeba histolytica alkyl sulfatase, putative 0.003 0.004 0.0081
Mycobacterium tuberculosis NAD(P)H quinone reductase LpdA 0.0242 0.069 0.4102
Brugia malayi Regulator of G protein signaling domain containing protein 0.0043 0.008 0.0115
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0026 0.0026 0.0041
Schistosoma mansoni Smad4 0.0019 0.0005 0.0007
Loa Loa (eye worm) hypothetical protein 0.015 0.0408 0.059
Leishmania major protein kinase, putative 0.0052 0.0107 0.0214
Echinococcus granulosus ubiquitin specific protease 41 0.0037 0.006 0.0095
Schistosoma mansoni aryl hydrocarbon receptor 0.0197 0.055 0.0868
Mycobacterium tuberculosis Probable aldehyde dehydrogenase 0.0061 0.0134 0.0784
Entamoeba histolytica hypothetical protein 0.0186 0.0518 0.1037
Loa Loa (eye worm) cytoplasmic intermediate filament protein 0.0044 0.0081 0.0117
Brugia malayi Pre-SET motif family protein 0.0096 0.0243 0.0351
Plasmodium vivax 6-phosphofructokinase, putative 0.003 0.0039 0.0078
Trypanosoma cruzi PAS-domain containing phosphoglycerate kinase, putative 0.0051 0.0104 0.0208
Plasmodium vivax hydroxyacyl glutathione hydrolase, putative 0.003 0.004 0.0081
Echinococcus multilocularis Jumonji, AT rich interactive domain 1B 0.0021 0.0011 0.0011
Onchocerca volvulus 0.024 0.0684 0.3038
Mycobacterium tuberculosis Conserved hypothetical protein 0.003 0.004 0.0221
Entamoeba histolytica hypothetical protein 0.0043 0.008 0.0159
Trichomonas vaginalis tubulin epsilon chain, putative 0.1261 0.3818 0.7652
Trypanosoma cruzi STE group serine/threonine-protein kinase, putative 0.0052 0.0107 0.0214
Loa Loa (eye worm) hypothetical protein 0.0088 0.0218 0.0315
Brugia malayi Nuclear hormone receptor family member nhr-49 0.006 0.013 0.0189
Schistosoma mansoni zinc phosphodiesterase 0.003 0.004 0.0063
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0031 0.0041 0.006
Trichomonas vaginalis tubulin gamma chain, putative 0.0941 0.2836 0.5683
Trichomonas vaginalis abcb9, putative 0.0021 0.0013 0.0025
Toxoplasma gondii phosphofructokinase PFKII 0.003 0.0039 0.0078
Brugia malayi MH2 domain containing protein 0.0019 0.0005 0.0007
Echinococcus multilocularis microtubule associated protein 2 0.2083 0.6339 0.6339
Trypanosoma cruzi PAB1-binding protein , putative 0.0102 0.026 0.052
Echinococcus multilocularis mothers against decapentaplegic 5 0.0042 0.0076 0.0076
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.006 0.013 0.0189
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0026 0.0026 0.0114
Loa Loa (eye worm) tubulin gamma chain 0.0941 0.2836 0.4103
Echinococcus granulosus single minded 2 0.0145 0.0393 0.0621
Plasmodium falciparum LCCL domain-containing protein 0.0139 0.0373 0.0747
Trichomonas vaginalis beta lactamase domain, putative 0.003 0.004 0.0081
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.0019 0.0005 0.0008
Mycobacterium tuberculosis Probable reductase 0.0218 0.0616 0.3656
Schistosoma mansoni regulator of G protein signaling 17 19 20 (rgs17 19 20) 0.0043 0.008 0.0125
Trichomonas vaginalis PIKK family atypical protein kinase 0.0055 0.0115 0.023
Toxoplasma gondii aldehyde dehydrogenase 0.0061 0.0134 0.0269
Loa Loa (eye worm) G protein signaling regulator EGL-10 0.0043 0.008 0.0115
Trichomonas vaginalis PIKK family atypical protein kinase 0.0055 0.0115 0.023
Loa Loa (eye worm) 6-phosphofructokinase 0.0111 0.0288 0.0416
Schistosoma mansoni tubulin subunit gamma 0.0941 0.2836 0.4474
Brugia malayi MH1 domain containing protein 0.0042 0.0076 0.011
Schistosoma mansoni single-minded 0.0197 0.055 0.0868
Echinococcus granulosus follistatin 0.0058 0.0125 0.0198
Brugia malayi aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase 0.0093 0.0233 0.0336
Loa Loa (eye worm) transcription factor SMAD2 0.0616 0.1837 0.2658
Schistosoma mansoni zinc phosphodiesterase 0.003 0.004 0.0063
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.002 0.0009 0.0019
Leishmania major ATP-dependent DEAD/H DNA helicase recQ, putative 0.0031 0.0043 0.0086
Brugia malayi Nuclear hormone receptor family member nhr-14 0.006 0.013 0.0189
Trichomonas vaginalis lipid A export ATP-binding/permease protein msba, putative 0.0021 0.0013 0.0025
Trichomonas vaginalis tubulin alpha-1 chain, putative 0.0759 0.2275 0.456
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.006 0.013 0.0206
Plasmodium vivax isocitrate dehydrogenase [NADP], mitochondrial, putative 0.0032 0.0044 0.0089
Brugia malayi PXA domain containing protein 0.0043 0.008 0.0115
Echinococcus granulosus Niemann Pick C1 protein 0.0282 0.0812 0.1282
Toxoplasma gondii beta tubulin 0.1643 0.499 1
Echinococcus granulosus lysine specific demethylase 5A 0.0064 0.0143 0.0225
Mycobacterium tuberculosis Conserved hypothetical protein 0.003 0.004 0.0221
Trichomonas vaginalis conserved hypothetical protein 0.0043 0.008 0.0159
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0327 0.0951 0.1906
Loa Loa (eye worm) alpha-tubulin 0.1261 0.3818 0.5524
Trichomonas vaginalis PIKK family atypical protein kinase 0.0054 0.0113 0.0227
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0327 0.0951 0.1906
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.002 0.0009 0.0019
Brugia malayi Chain A, Human Glyoxalase Ii With Cacodylate And Acetate Ions Present In The Active Site. 0.003 0.004 0.0058
Toxoplasma gondii 4'-phosphopantetheinyl transferase superfamily protein 0.0026 0.0027 0.0055
Plasmodium vivax delta tubulin, putative 0.0411 0.1209 0.2423
Schistosoma mansoni aminoadipate-semialdehyde dehydrogenase 0.0093 0.0233 0.0367
Schistosoma mansoni survival motor neuron protein 0.0048 0.0095 0.015
Plasmodium falciparum alpha tubulin 2 0.1261 0.3818 0.7652
Toxoplasma gondii thioredoxin reductase 0.0096 0.024 0.0481
Trichomonas vaginalis DNA helicase recq, putative 0.0031 0.0043 0.0086
Mycobacterium tuberculosis Probable transmembrane multidrug efflux pump 0.0021 0.0013 0.0057
Toxoplasma gondii isocitrate dehydrogenase 0.0032 0.0044 0.0089
Mycobacterium leprae Possible regulatory protein 0.0051 0.0104 0.0834
Echinococcus multilocularis retinoic acid receptor rxr beta a retinoic acid receptor rxr alpha a retinoic acid receptor rxr alpha 0.0026 0.0026 0.0026
Schistosoma mansoni alpha tubulin 0.1261 0.3818 0.6024
Trypanosoma cruzi ATP-dependent 6-phosphofructokinase, glycosomal 0.0111 0.0288 0.0577
Loa Loa (eye worm) hypothetical protein 0.0043 0.008 0.0115
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.006 0.013 0.0189
Toxoplasma gondii metallo-beta-lactamase domain-containing protein 0.003 0.004 0.0081
Echinococcus granulosus expressed conserved protein 0.0185 0.0516 0.0814
Plasmodium vivax holo-[acyl-carrier-protein] synthase, putative 0.0026 0.0027 0.0055
Schistosoma mansoni regulator of G protein signaling 0.0043 0.008 0.0125
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.006 0.013 0.0189
Loa Loa (eye worm) inositol-1 0.0045 0.0084 0.0121
Mycobacterium ulcerans aldehyde dehydrogenase 0.0061 0.0134 0.1112
Schistosoma mansoni NADP-specific isocitrate dehydrogenase 0.0032 0.0044 0.007
Trichomonas vaginalis D-aminoacylase, putative 0.0088 0.0218 0.0437
Plasmodium falciparum holo-[acyl-carrier-protein] synthase, putative 0.0026 0.0027 0.0055
Loa Loa (eye worm) hypothetical protein 0.0257 0.0736 0.1065
Echinococcus multilocularis regulator of G protein signaling 7 0.0043 0.008 0.008
Loa Loa (eye worm) hypothetical protein 0.0034 0.0052 0.0075
Echinococcus multilocularis nuclear factor of activated T cells 5 0.0073 0.0173 0.0173
Brugia malayi Nuclear hormone receptor family member nhr-25 0.006 0.013 0.0189
Mycobacterium leprae DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE 0.0242 0.069 0.5699
Brugia malayi MH1 domain containing protein 0.0023 0.0018 0.0026
Trypanosoma brucei beta tubulin 0.1643 0.499 1
Echinococcus granulosus Tubulin beta 2C chain 0.1643 0.499 0.7872
Trypanosoma cruzi trypanothione reductase, putative 0.0033 0.0049 0.0097
Schistosoma mansoni thyroid hormone receptor 0.006 0.013 0.0206
Brugia malayi SPARC precursor 0.0058 0.0125 0.0181
Brugia malayi Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain containing protein 0.0024 0.0022 0.0031
Schistosoma mansoni nuclear hormone receptor superfamily protein-related 0.0026 0.0026 0.0041
Trichomonas vaginalis phosphofructokinase, putative 0.003 0.0039 0.0078
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.006 0.013 0.0189
Loa Loa (eye worm) intermediate filament protein 0.0082 0.0197 0.0286
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.006 0.013 0.0189
Loa Loa (eye worm) hypothetical protein 0.0058 0.0125 0.0181
Schistosoma mansoni ataxia telangiectasia mutated (atm)-related 0.0091 0.0228 0.0359
Echinococcus multilocularis nuclear receptor subfamily 4 group A 0.0026 0.0026 0.0026
Brugia malayi nuclear receptor RXR 0.0026 0.0026 0.0037
Trichomonas vaginalis tubulin alpha chain, putative 0.0503 0.149 0.2986
Echinococcus multilocularis ATP binding cassette sub family B 0.0021 0.0012 0.0012
Trypanosoma brucei alpha tubulin, putative 0.0503 0.149 0.2986
Schistosoma mansoni alpha tubulin 0.1261 0.3818 0.6024
Schistosoma mansoni tubulin subunit alpha 0.0411 0.1209 0.1907
Trichomonas vaginalis tubulin alpha-1 chain, putative 0.085 0.2556 0.5123
Trypanosoma cruzi STE group serine/threonine-protein kinase, putative 0.0052 0.0107 0.0214
Trichomonas vaginalis multidrug resistance protein 1, 2, putative 0.0021 0.0013 0.0025
Onchocerca volvulus 0.0021 0.0013 0.0056
Echinococcus multilocularis agrin 0.0058 0.0125 0.0125
Brugia malayi Cytochrome P450 family protein 0.0055 0.0115 0.0166
Trichomonas vaginalis PIKK family atypical protein kinase 0.0049 0.0098 0.0197
Loa Loa (eye worm) phosphatidylinositol 3 0.0031 0.0041 0.006
Echinococcus multilocularis tubulin alpha 0.0914 0.2752 0.2752
Echinococcus granulosus intermediate filament protein 0.0082 0.0197 0.0311
Trypanosoma cruzi tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0066 0.0149 0.0299
Entamoeba histolytica metallo-beta-lactamase family protein 0.003 0.004 0.0081
Echinococcus multilocularis A kinase anchor protein 10, mitochondrial 0.0043 0.008 0.008
Brugia malayi Tubulin gamma chain 0.0941 0.2836 0.4103
Leishmania major beta tubulin 0.1643 0.499 1
Schistosoma mansoni hypothetical protein 0.082 0.2462 0.3885
Loa Loa (eye worm) nuclear hormone receptor 0.0026 0.0026 0.0037
Loa Loa (eye worm) raf kinase 0.0044 0.0082 0.0119
Trichomonas vaginalis tubulin, putative 0.0503 0.149 0.2986
Echinococcus granulosus nuclear factor of activated T cells 5 0.0073 0.0173 0.0272
Treponema pallidum NADH oxidase 0.0033 0.0049 0.0362
Schistosoma mansoni ap endonuclease 0.0019 0.0005 0.0008
Brugia malayi 6-phosphofructokinase 0.0111 0.0289 0.0417
Brugia malayi PAS domain containing protein 0.0197 0.055 0.0796
Trypanosoma cruzi tubulin gamma chain 0.0941 0.2836 0.5683
Leishmania major target of rapamycin (TOR) kinase 1, putative 0.0091 0.0228 0.0457
Trichomonas vaginalis PIKK family atypical protein kinase 0.0073 0.017 0.0341
Schistosoma mansoni hypothetical protein 0.0082 0.0198 0.0312
Trichomonas vaginalis tubulin beta chain, putative 0.1261 0.3818 0.7652
Plasmodium falciparum dihydrolipoyl dehydrogenase, mitochondrial 0.0033 0.0049 0.0097
Plasmodium vivax tubulin alpha chain, putative 0.1261 0.3818 0.7652
Brugia malayi hypothetical protein 0.0659 0.197 0.2851
Trichomonas vaginalis tubulin gamma chain, putative 0.0941 0.2835 0.5681
Brugia malayi Angiotensin-converting enzyme family protein 0.2269 0.6912 1
Brugia malayi ATP-dependent DNA helicase, RecQ family protein 0.0029 0.0035 0.0051
Schistosoma mansoni 6-phosphofructokinase 0.0111 0.0288 0.0454
Echinococcus granulosus ecdysone induced protein 78C 0.006 0.013 0.0206
Mycobacterium ulcerans cytochrome P450 108B4 Cyp108B4 0.0018 0.0003 0.0026
Trichomonas vaginalis PIKK family atypical protein kinase 0.0068 0.0156 0.0312
Schistosoma mansoni hypothetical protein 0.0082 0.0198 0.0312
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0103 0.0262 0.0524
Echinococcus multilocularis follistatin 0.0058 0.0125 0.0125
Leishmania major beta tubulin 0.1643 0.499 1
Loa Loa (eye worm) hypothetical protein 0.0058 0.0125 0.0181
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0032 0.0044 0.0044
Mycobacterium tuberculosis Conserved hypothetical protein 0.002 0.0009 0.0036
Trypanosoma cruzi metallo-beta-lactamase superfamily, putative 0.003 0.004 0.0081
Plasmodium vivax dihydrolipoyl dehydrogenase, mitochondrial, putative 0.0033 0.0049 0.0097
Brugia malayi Tubulin alpha-2 chain 0.1261 0.3818 0.5524
Echinococcus granulosus neuropeptide receptor A26 0.0931 0.2804 0.4424
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0034 0.0052 0.0081
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0031 0.0043 0.0068
Trichomonas vaginalis ABC transporter, half transporter, putative 0.0021 0.0013 0.0025
Entamoeba histolytica hypothetical protein 0.0186 0.0518 0.1037
Leishmania major cytochrome p450-like protein 0.0055 0.0115 0.023
Loa Loa (eye worm) hypothetical protein 0.003 0.004 0.0058
Entamoeba histolytica myo-inositol monophosphatase, putative 0.0045 0.0084 0.0168
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0033 0.0049 0.0097
Leishmania major alpha tubulin 0.1261 0.3818 0.7652
Trichomonas vaginalis PIKK family atypical protein kinase 0.0068 0.0156 0.0312
Entamoeba histolytica metallo-beta-lactamase family protein 0.003 0.004 0.0081
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.0024 0.0021 0.0042
Echinococcus multilocularis tubulin alpha chain 0.1261 0.3818 0.3818
Loa Loa (eye worm) hypothetical protein 0.0026 0.0026 0.0037
Echinococcus multilocularis tubulin alpha 3 chain 0.1261 0.3818 0.3818
Mycobacterium tuberculosis Probable NADH dehydrogenase Ndh 0.0218 0.0616 0.3656
Echinococcus granulosus ETHE1 protein 0.003 0.004 0.0063
Echinococcus multilocularis leukotriene A 4 hydrolase 0.0325 0.0944 0.0944
Mycobacterium tuberculosis Conserved protein 0.0088 0.0218 0.1283
Loa Loa (eye worm) cytochrome P450 family protein 0.0018 0.0003 0.0005
Toxoplasma gondii pyruvate dehydrogenase complex subunit PDH-E3II 0.0033 0.0049 0.0097
Leishmania major beta tubulin 0.1643 0.499 1
Brugia malayi follicle stimulating hormone receptor 0.0242 0.0691 0.0999
Plasmodium vivax tubulin alpha chain, putative 0.1261 0.3818 0.7652
Trypanosoma cruzi tubulin delta chain 0.058 0.1728 0.3464
Trichomonas vaginalis tubulin alpha-1 chain, putative 0.1261 0.3818 0.7652
Toxoplasma gondii hydroxyacylglutathione hydrolase 0.003 0.004 0.0081
Schistosoma mansoni Tr4/Tr2 (homologue) 0.006 0.013 0.0206
Echinococcus granulosus thyroid hormone receptor alpha 0.0026 0.0026 0.0041
Schistosoma mansoni hypothetical protein 0.0018 0.0003 0.0005
Loa Loa (eye worm) hypothetical protein 0.1261 0.3818 0.5524
Echinococcus multilocularis survival motor neuron protein 1 0.0236 0.0671 0.0671
Plasmodium vivax multidomain scavenger receptor, putative 0.0139 0.0373 0.0747
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.006 0.013 0.0579
Loa Loa (eye worm) nuclear factor I 0.0023 0.0018 0.0026
Wolbachia endosymbiont of Brugia malayi dihydrolipoamide dehydrogenase E3 component 0.0033 0.0049 0.0362
Schistosoma mansoni hypothetical protein 0.0048 0.0095 0.015
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0037 0.006 0.0121
Onchocerca volvulus 0.0051 0.0104 0.0461
Brugia malayi MAP kinase sur-1 0.0103 0.0262 0.0379
Echinococcus multilocularis jun protein 0.0264 0.0758 0.0758
Trichomonas vaginalis abcb9, putative 0.0021 0.0013 0.0025
Trichomonas vaginalis D-aminoacylase, putative 0.0088 0.0218 0.0437
Echinococcus granulosus tubulin alpha 1C chain 0.1261 0.3818 0.6024
Loa Loa (eye worm) hypothetical protein 0.0036 0.0059 0.0085
Plasmodium vivax apurinic/apyrimidinic endonuclease Apn1, putative 0.0077 0.0184 0.0368
Echinococcus granulosus peroxisome assembly protein 26 0.1261 0.3818 0.6024
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0033 0.0049 0.0097
Mycobacterium tuberculosis Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB 0.0218 0.0616 0.3656
Mycobacterium ulcerans cytochrome p450 150 cyp150 0.0018 0.0003 0.0026
Loa Loa (eye worm) hypothetical protein 0.0043 0.008 0.0115
Echinococcus granulosus ATP binding cassette subfamily B MDR:TAP 0.0021 0.0013 0.002
Toxoplasma gondii non-specific serine/threonine protein kinase 0.0019 0.0006 0.0012
Echinococcus multilocularis metallo beta lactamase domain containing protein 0.003 0.004 0.004
Trichomonas vaginalis tubulin epsilon chain, putative 0.1261 0.3818 0.7652
Echinococcus granulosus tubulin alpha chain 0.1261 0.3818 0.6024
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.006 0.013 0.0206
Echinococcus granulosus neuropeptide s receptor 0.0931 0.2804 0.4424
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.066 0.1973 0.2855
Echinococcus granulosus thioredoxin glutathione reductase 0.0096 0.024 0.0379
Trypanosoma brucei hypothetical protein, conserved 0.0026 0.0027 0.0055
Schistosoma mansoni tubulin subunit beta 0.1643 0.499 0.7872
Plasmodium falciparum tubulin gamma chain 0.0941 0.2836 0.5683
Leishmania major alpha tubulin 0.1261 0.3818 0.7652
Echinococcus granulosus beta LACTamase domain containing family member 0.0088 0.0218 0.0344
Plasmodium vivax AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0019 0.0005 0.001
Echinococcus granulosus Regulator of G protein signaling 20 0.0043 0.008 0.0125
Trypanosoma brucei phosphatidylinositol 4-kinase, putative 0.0091 0.0228 0.0457
Trichomonas vaginalis phosphofructokinase, putative 0.003 0.0039 0.0078
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.0088 0.0218 0.1283
Trichomonas vaginalis conserved hypothetical protein 0.002 0.0009 0.0019
Brugia malayi Kazal-type serine protease inhibitor domain containing protein 0.0058 0.0125 0.0181
Echinococcus granulosus phosphatidylinositol 3 and 4 kinase 0.0031 0.0041 0.0065
Onchocerca volvulus 0.0093 0.0233 0.1033
Mycobacterium tuberculosis holo-[acyl-carrier protein] synthase AcpS (holo-ACP synthase) (CoA:APO-[ACP]pantetheinephosphotransferase) (CoA:APO-[acyl-carrie 0.0026 0.0027 0.0144
Echinococcus granulosus zinc phosphodiesterase 0.003 0.004 0.0063
Entamoeba histolytica metallo-beta-lactamase family protein 0.003 0.004 0.0081
Schistosoma mansoni tubulin subunit beta 0.1643 0.499 0.7872
Echinococcus multilocularis phosphatidylinositol 3 and 4 kinase 0.0031 0.0041 0.0041
Leishmania major target of rapamycin (TOR) kinase 2, putative 0.0091 0.0228 0.0457
Brugia malayi tubulin alpha chain - mouse 0.1261 0.3818 0.5524
Brugia malayi Probable G protein-coupled receptor kinase F19C6.1, putative 0.0044 0.0082 0.0119
Trichomonas vaginalis ap endonuclease, putative 0.0019 0.0005 0.001
Loa Loa (eye worm) hypothetical protein 0.0026 0.0026 0.0037
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.006 0.013 0.013
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.002 0.0009 0.0019
Mycobacterium leprae PROBABLE 6-PHOSPHOFRUCTOKINASE PFKA (PHOSPHOHEXOKINASE) (PHOSPHOFRUCTOKINASE) 0.0111 0.0288 0.2361
Toxoplasma gondii CMGC kinase, MAPK family (ERK) MAPK-1 0.0103 0.0262 0.0524
Loa Loa (eye worm) hypothetical protein 0.0034 0.0052 0.0075
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0033 0.0049 0.0097
Mycobacterium ulcerans hydrolase 0.003 0.004 0.0333
Loa Loa (eye worm) hypothetical protein 0.008 0.0193 0.0279
Echinococcus multilocularis Tubulin beta 2C chain 0.1643 0.499 0.499
Mycobacterium tuberculosis Inositol-1-monophosphatase SuhB 0.004 0.007 0.0397
Echinococcus granulosus ATP binding cassette subfamily B MDR:TAP 0.0021 0.0013 0.002
Onchocerca volvulus Putative hydroxypyruvate isomerase 0.002 0.0009 0.0041
Brugia malayi MH1 domain containing protein 0.0023 0.0018 0.0026
Schistosoma mansoni hypothetical protein 0.0186 0.0518 0.0816
Trichomonas vaginalis ATP-binding cassette transporter, putative 0.0021 0.0013 0.0025
Brugia malayi Kazal-type serine protease inhibitor domain containing protein 0.0058 0.0125 0.0181
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0033 0.0049 0.0097
Trypanosoma cruzi Phosphatidylinositol 3-kinase tor1 0.0091 0.0228 0.0457
Plasmodium falciparum alpha tubulin 1 0.1261 0.3818 0.7652
Echinococcus granulosus multidrug resistance protein 1 0.0021 0.0013 0.002
Plasmodium vivax tubulin epsilon chain, putative 0.0941 0.2835 0.5681
Echinococcus granulosus dihydrolipoamide dehydrogenase 0.0033 0.0049 0.0077
Leishmania major beta tubulin 0.1643 0.499 1
Loa Loa (eye worm) thioredoxin reductase 0.0096 0.024 0.0347
Trichomonas vaginalis conserved hypothetical protein 0.0043 0.008 0.0159
Trichomonas vaginalis PIKK family atypical protein kinase 0.0068 0.0156 0.0312
Mycobacterium ulcerans cytochrome P450 188A3 Cyp188A3 0.0018 0.0003 0.0026
Trypanosoma cruzi isocitrate dehydrogenase, putative 0.0032 0.0044 0.0089
Loa Loa (eye worm) hypothetical protein 0.006 0.013 0.0189
Echinococcus granulosus nuclear receptor subfamily 4 group A 0.0026 0.0026 0.0041
Trypanosoma cruzi zeta tubulin, putative 0.0694 0.2077 0.4163
Onchocerca volvulus Putative organic anion transporter 0.0085 0.0208 0.0923
Schistosoma mansoni jun-related protein 0.0215 0.0606 0.0956
Toxoplasma gondii histone lysine methyltransferase SET1 0.0175 0.0484 0.0971
Loa Loa (eye worm) hypothetical protein 0.006 0.013 0.0189
Echinococcus multilocularis ATP binding cassette subfamily B (MDR:TAP) 0.0021 0.0013 0.0013
Echinococcus multilocularis lysine specific demethylase 5A 0.0059 0.0127 0.0127
Trypanosoma cruzi target of rapamycin kinase 3 0.0073 0.0171 0.0342
Trichomonas vaginalis conserved hypothetical protein 0.003 0.004 0.0081
Mycobacterium leprae conserved hypothetical protein 0.0026 0.0027 0.0201
Leishmania major 2-oxoglutarate dehydrogenase, e3 component, lipoamidedehydrogenase-like protein 0.0033 0.0049 0.0097
Trichomonas vaginalis PIKK family atypical protein kinase 0.0061 0.0135 0.0271
Echinococcus multilocularis Aryl hydrocarbon receptor nuclear 0.0051 0.0104 0.0104
Brugia malayi metallo-beta-lactamase superfamily protein 0.003 0.004 0.0058
Loa Loa (eye worm) hypothetical protein 0.0019 0.0004 0.0006
Mycobacterium ulcerans fructose-bisphosphate aldolase 0.016 0.0437 0.3618
Echinococcus granulosus tubulin gamma 1 chain 0.0941 0.2836 0.4474
Trypanosoma cruzi metallo-beta-lactamase-like protein, putative 0.003 0.004 0.0081
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0026 0.0026 0.0026
Leishmania major ATP-binding cassette protein subfamily B, member 2, putative 0.0021 0.0013 0.0025
Echinococcus multilocularis lamin dm0 0.0082 0.0197 0.0197
Plasmodium falciparum ATP-dependent 6-phosphofructokinase 0.003 0.0039 0.0078
Brugia malayi alpha keto acid dehydrogenase complex, E3 component, lipoamide dehydrogenase 0.0024 0.0022 0.0031
Trichomonas vaginalis conserved hypothetical protein 0.0019 0.0006 0.0012
Brugia malayi regulator of G-protein signaling rgs-7 0.0043 0.008 0.0115
Echinococcus granulosus mitogen activated protein kinase 0.0103 0.0262 0.0413
Loa Loa (eye worm) hypothetical protein 0.0034 0.0052 0.0075
Loa Loa (eye worm) hypothetical protein 0.0139 0.0373 0.0539
Trichomonas vaginalis disulfide oxidoreductase, putative 0.0039 0.0067 0.0135
Echinococcus multilocularis regulator of G protein signaling 3 0.0043 0.008 0.008
Mycobacterium ulcerans hypothetical protein 0.003 0.004 0.0333
Loa Loa (eye worm) CXXC zinc finger family protein 0.009 0.0222 0.0322
Entamoeba histolytica FKBP-rapamycin associated protein (FRAP), putative 0.0091 0.0228 0.0457
Plasmodium falciparum multidrug resistance protein 1 0.0021 0.0013 0.0025
Schistosoma mansoni hypothetical protein 0.0046 0.0087 0.0138
Toxoplasma gondii tubulin/FtsZ family, GTPase domain-containing protein 0.0914 0.2752 0.5515
Mycobacterium ulcerans cytochrome P450 140A5 Cyp140A5 0.0018 0.0003 0.0026
Entamoeba histolytica P-glycoprotein-2 0.0021 0.0013 0.0025
Trypanosoma brucei phosphatidylinositol 3-kinase tor, putative 0.0043 0.008 0.016
Trypanosoma brucei zeta tubulin 0.0694 0.2077 0.4163
Brugia malayi Nuclear hormone receptor E75 0.0026 0.0026 0.0037
Echinococcus multilocularis inositol monophosphatase 1 0.0045 0.0084 0.0084
Loa Loa (eye worm) hypothetical protein 0.0043 0.008 0.0115
Leishmania major PAS-domain containing phosphoglycerate kinase, putative 0.0051 0.0104 0.0208
Trypanosoma cruzi Lanosterol 14-alpha demethylase 0.0018 0.0003 0.0006
Trichomonas vaginalis DNA helicase recq1, putative 0.0041 0.0074 0.0148
Echinococcus multilocularis 0.0018 0.0003 0.0003
Trypanosoma cruzi STE/STE11 serine/threonine-protein kinase, putative 0.0052 0.0107 0.0214
Loa Loa (eye worm) angiotensin-converting enzyme family protein 0.2269 0.6912 1
Trichomonas vaginalis conserved hypothetical protein 0.003 0.004 0.0081
Trichomonas vaginalis beta lactamase domain, putative 0.003 0.004 0.0081
Loa Loa (eye worm) AGC/GRK/BARK protein kinase 0.0044 0.0082 0.0119
Echinococcus granulosus hydroxyacylglutathione hydrolase 0.003 0.004 0.0063
Trichomonas vaginalis PIKK family atypical protein kinase 0.0059 0.0129 0.0259
Trichomonas vaginalis adenylate cyclase, type VII, putative 0.0051 0.0104 0.0208
Trichomonas vaginalis PIKK family atypical protein kinase 0.0073 0.017 0.0341
Loa Loa (eye worm) hypothetical protein 0.0043 0.008 0.0115
Onchocerca volvulus 0.015 0.0408 0.1809
Loa Loa (eye worm) tubulin alpha 2 0.085 0.2556 0.3698
Loa Loa (eye worm) tubulin beta-4 chain 0.1643 0.499 0.7219
Echinococcus multilocularis Smad4 0.0042 0.0076 0.0076
Echinococcus granulosus ATP dependent DNA helicase Q1 0.0029 0.0035 0.0055
Trichomonas vaginalis PIKK family atypical protein kinase 0.0068 0.0156 0.0312
Echinococcus multilocularis Tubulin beta 2C chain 0.1643 0.499 0.499
Loa Loa (eye worm) hypothetical protein 0.0034 0.0052 0.0075
Mycobacterium tuberculosis Beta lactamase like protein 0.003 0.004 0.0221
Schistosoma mansoni CREB-binding protein 1 (SmCBP1) 0.0099 0.025 0.0395
Echinococcus granulosus tubulin alpha 0.0914 0.2752 0.4341
Brugia malayi beta-lactamase 0.0088 0.0218 0.0315
Mycobacterium ulcerans cell division protein FtsZ 0.0411 0.1209 1
Toxoplasma gondii endonuclease IV APN 0.0077 0.0184 0.0368
Leishmania major phosphatidylinositol 3-related kinase, putative 0.0031 0.0041 0.0083
Mycobacterium ulcerans lipase LipD 0.0088 0.0218 0.1803
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0327 0.0951 0.1906
Trypanosoma cruzi cytochrome p450-like protein, putative 0.0018 0.0003 0.0006
Schistosoma mansoni microtubule-associated protein tau 0.2083 0.6339 1
Brugia malayi hypothetical protein 0.0102 0.026 0.0375
Echinococcus granulosus organic anion transporting polypeptide 30B 0.0085 0.0208 0.0328
Brugia malayi conserved hypotetical protein 0.0026 0.0026 0.0037
Loa Loa (eye worm) metallo-beta-lactamase superfamily protein 0.003 0.004 0.0058
Trypanosoma brucei ATP-dependent 6-phosphofructokinase, glycosomal 0.0111 0.0288 0.0577
Brugia malayi F/Y-rich N-terminus family protein 0.0031 0.0042 0.006
Schistosoma mansoni patched 1 0.0085 0.0207 0.0326
Brugia malayi hypothetical protein 0.0139 0.0373 0.0539
Echinococcus granulosus tubulin alpha 3 chain 0.1261 0.3818 0.6024
Loa Loa (eye worm) doublecortin family protein 0.0139 0.0373 0.0539
Onchocerca volvulus 0.0208 0.0584 0.2592
Echinococcus granulosus 6 phosphofructokinase 0.0111 0.0288 0.0454
Echinococcus granulosus Polycystic kidney disease protein 0.0139 0.0373 0.0588
Entamoeba histolytica hypothetical protein 0.0026 0.0027 0.0055
Echinococcus multilocularis regulator of G protein signaling 0.0043 0.008 0.008
Mycobacterium tuberculosis Probable lipase LipE 0.0088 0.0218 0.1283
Onchocerca volvulus 0.003 0.004 0.0179
Mycobacterium tuberculosis Possible hydrolase 0.003 0.004 0.0221
Loa Loa (eye worm) hypothetical protein 0.0051 0.0104 0.015
Schistosoma mansoni RAR-like nuclear receptor 0.006 0.013 0.0206
Loa Loa (eye worm) hydroxyacylglutathione hydrolase cytoplasmic 0.003 0.004 0.0058
Giardia lamblia Hydroxyacylglutathione hydrolase 0.003 0.004 0.0071
Trypanosoma cruzi hypothetical protein, conserved 0.0088 0.0218 0.0437
Schistosoma mansoni hypothetical protein 0.0875 0.2634 0.4155
Echinococcus multilocularis cytoplasmic intermediate filament protein 0.0039 0.0068 0.0068
Echinococcus multilocularis tubulin subunit TubB 0.1261 0.3818 0.3818
Schistosoma mansoni serine/threonine protein kinase 0.0044 0.0082 0.013
Echinococcus multilocularis isocitrate dehydrogenase 2 (NADP+) 0.0032 0.0044 0.0044
Onchocerca volvulus Protein ultraspiracle homolog 0.006 0.013 0.0579
Trichomonas vaginalis PIKK family atypical protein kinase 0.0031 0.0041 0.0083
Trypanosoma brucei metallo-beta-lactamase-like protein, putative 0.003 0.004 0.0081
Trichomonas vaginalis PIKK family atypical protein kinase 0.0031 0.0041 0.0083
Echinococcus granulosus Jumonji AT rich interactive domain 1B 0.0021 0.0011 0.0017
Leishmania major alpha tubulin 0.1261 0.3818 0.7652
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0031 0.0043 0.0043
Entamoeba histolytica type A flavoprotein, putative 0.003 0.004 0.0081
Echinococcus multilocularis tubulin epsilon chain 0.0941 0.2835 0.2835
Echinococcus granulosus FTZ F1 alpha 0.006 0.013 0.0206
Mycobacterium ulcerans epimerase 0.002 0.0009 0.0077
Trichomonas vaginalis tubulin beta chain, putative 0.1261 0.3818 0.7652
Echinococcus granulosus tubulin alpha chain 0.1261 0.3818 0.6024
Echinococcus granulosus mixed lineage leukemia protein mll 0.0026 0.0026 0.0041
Loa Loa (eye worm) leukotriene A4 hydrolase 0.0325 0.0944 0.1365
Mycobacterium tuberculosis Probable oxidoreductase 0.0242 0.069 0.4102
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0045 0.0084 0.0168
Loa Loa (eye worm) CYP4Cod1 0.0055 0.0115 0.0166
Trichomonas vaginalis tubulin alpha chain, putative 0.0914 0.2752 0.5515
Trypanosoma cruzi hypothetical protein, conserved 0.0088 0.0218 0.0437
Loa Loa (eye worm) hypothetical protein 0.0088 0.0218 0.0315
Plasmodium vivax ADP-dependent DNA helicase RecQ, putative 0.0025 0.0023 0.0045
Toxoplasma gondii LsmAD domain-containing protein 0.0102 0.026 0.052
Loa Loa (eye worm) Smad1 0.0042 0.0076 0.011
Echinococcus multilocularis tubulin beta 1 chain 0.1643 0.499 0.499
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0037 0.006 0.0087
Echinococcus granulosus metallo beta lactamase domain containing protein 0.003 0.004 0.0063
Plasmodium falciparum ADP-dependent DNA helicase RecQ 0.0039 0.0066 0.0132
Onchocerca volvulus 0.0139 0.0373 0.1655
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.006 0.013 0.0189
Echinococcus granulosus Protein patched homolog 1 0.0085 0.0207 0.0326
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0033 0.0049 0.0097
Brugia malayi Nuclear hormone receptor family member nhr-19 0.006 0.013 0.0189
Onchocerca volvulus 0.003 0.004 0.0179
Brugia malayi beta-tubulin, identical 0.1643 0.499 0.7219
Trichomonas vaginalis conserved hypothetical protein 0.0043 0.008 0.0159
Mycobacterium ulcerans beta lactamase-like protein 0.003 0.004 0.0333
Schistosoma mansoni smad1 5 8 and 0.0042 0.0076 0.012
Leishmania major alpha tubulin 0.1261 0.3818 0.7652
Trichomonas vaginalis conserved hypothetical protein 0.0043 0.008 0.0159
Loa Loa (eye worm) hypothetical protein 0.0104 0.0265 0.0384
Trichomonas vaginalis taga, putative 0.0021 0.0013 0.0025
Treponema pallidum fructose-bisphosphate aldolase 0.0327 0.0951 0.7856
Toxoplasma gondii ABC1 family protein 0.0088 0.0218 0.0437
Trichomonas vaginalis beta lactamase domain, putative 0.003 0.004 0.0081
Entamoeba histolytica phosphatidylinositol3-kinaseTor2, putative 0.0091 0.0228 0.0457
Echinococcus granulosus tubulin alpha chain 0.1261 0.3818 0.6024
Trichomonas vaginalis beta lactamase domain, putative 0.003 0.004 0.0081
Echinococcus multilocularis smad 0.0042 0.0076 0.0076
Plasmodium falciparum dihydrolipoyl dehydrogenase, apicoplast 0.0033 0.0049 0.0097
Brugia malayi exodeoxyribonuclease III family protein 0.0019 0.0005 0.0007
Loa Loa (eye worm) hypoxia-induced factor 1 0.0608 0.1814 0.2624
Loa Loa (eye worm) tyrosyl-DNA phosphodiesterase 0.0066 0.0149 0.0216
Echinococcus granulosus beta-adrenergic receptor kinase 0.0044 0.0082 0.013
Schistosoma mansoni hypothetical protein 0.0139 0.0373 0.0588
Schistosoma mansoni regulator of G protein signaling 0.0043 0.008 0.0125
Trypanosoma brucei cytochrome P450, putative 0.0055 0.0115 0.023
Loa Loa (eye worm) hypothetical protein 0.0386 0.113 0.1635
Trypanosoma brucei PAB1-binding protein , putative 0.0102 0.026 0.052
Mycobacterium ulcerans hypothetical protein 0.003 0.004 0.0333
Echinococcus multilocularis geminin 0.0875 0.2634 0.2634
Trichomonas vaginalis tubulin epsilon chain, putative 0.0411 0.1209 0.2423
Onchocerca volvulus Putative organic anion transporter 0.0085 0.0208 0.0923
Loa Loa (eye worm) sodium-independent organic anion transporter 0.0085 0.0208 0.0301
Chlamydia trachomatis holo [acyl-carrier protein] synthase 0.0026 0.0027 0.0859
Echinococcus multilocularis ETHE1 protein 0.003 0.004 0.004
Trichomonas vaginalis conserved hypothetical protein 0.002 0.0009 0.0019
Entamoeba histolytica exodeoxyribonuclease III, putative 0.0019 0.0005 0.001
Echinococcus multilocularis axis inhibition protein axin 0.0043 0.008 0.008
Mycobacterium tuberculosis Probable hydrolase 0.0088 0.0218 0.1283
Trichomonas vaginalis conserved hypothetical protein 0.003 0.004 0.0081
Brugia malayi Tubulin alpha chain 0.0411 0.1209 0.1749
Trypanosoma brucei inositol-1(or 4)-monophosphatase 1, putative 0.0045 0.0084 0.0168
Schistosoma mansoni tubulin subunit alpha 0.1261 0.3818 0.6024
Brugia malayi hypothetical protein 0.0186 0.0518 0.0749
Leishmania major alpha tubulin 0.1261 0.3818 0.7652
Mycobacterium ulcerans cytochrome P450 105Q4 Cyp105Q4 0.0018 0.0003 0.0026
Loa Loa (eye worm) phosphofructokinase 0.0111 0.0288 0.0416
Echinococcus granulosus lamin 0.0082 0.0197 0.0311
Giardia lamblia Hydroxyacylglutathione hydrolase 0.003 0.004 0.0071
Schistosoma mansoni lamin 0.0082 0.0197 0.0311
Echinococcus multilocularis regulator of G protein signaling 7 0.0043 0.008 0.008
Leishmania major beta tubulin 0.1643 0.499 1
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0026 0.0026 0.0026
Trichomonas vaginalis abcb9, putative 0.0021 0.0013 0.0025
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0032 0.0044 0.0044
Plasmodium vivax SET domain protein, putative 0.0096 0.0243 0.0487
Brugia malayi ecdysteroid receptor 0.006 0.013 0.0189
Trichomonas vaginalis conserved hypothetical protein 0.0051 0.0104 0.0208
Loa Loa (eye worm) hypothetical protein 0.003 0.004 0.0058
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0032 0.0044 0.0044
Leishmania major beta tubulin 0.1643 0.499 1
Toxoplasma gondii NADPH-glutathione reductase 0.0033 0.0049 0.0097
Brugia malayi Isocitrate dehydrogenase 0.0032 0.0044 0.0064
Plasmodium falciparum ataxin-2 like protein, putative 0.0102 0.026 0.052
Brugia malayi isocitrate dehydrogenase 0.0032 0.0044 0.0064
Leishmania major trypanothione reductase 0.0096 0.024 0.0481
Onchocerca volvulus 0.0048 0.0095 0.0421
Echinococcus multilocularis ATP binding cassette subfamily B (MDR:TAP) 0.0021 0.0013 0.0013
Plasmodium vivax 6-phosphofructokinase, putative 0.003 0.0039 0.0078
Schistosoma mansoni hypothetical protein 0.0215 0.0606 0.0956
Trypanosoma brucei alpha tubulin 0.1261 0.3818 0.7652
Brugia malayi DNA-(Apurinic or apyrimidinic site) lyase 0.0077 0.0184 0.0266
Echinococcus granulosus Tubulin beta 2C chain 0.1643 0.499 0.7872
Trypanosoma cruzi epsilon tubulin, putative 0.0941 0.2835 0.5681
Schistosoma mansoni retinoic acid receptor RXR 0.006 0.013 0.0206
Trichomonas vaginalis PIKK family atypical protein kinase 0.0049 0.0098 0.0197
Loa Loa (eye worm) MH2 domain-containing protein 0.0019 0.0005 0.0007
Echinococcus multilocularis sterol regulatory element binding protein 0.0085 0.0207 0.0207
Loa Loa (eye worm) hypothetical protein 0.0077 0.0184 0.0266
Loa Loa (eye worm) nuclear receptor nhr-7B 0.0026 0.0026 0.0037
Echinococcus granulosus tubulin alpha chain 0.1261 0.3818 0.6024
Schistosoma mansoni smad 0.0019 0.0005 0.0007
Plasmodium falciparum glutathione reductase 0.0096 0.024 0.0481
Schistosoma mansoni aldehyde dehydrogenase 0.0061 0.0134 0.0212
Echinococcus granulosus regulator of G protein signaling 7 0.0043 0.008 0.0125
Onchocerca volvulus 0.0085 0.0208 0.0923
Loa Loa (eye worm) BEN-1 protein 0.1643 0.499 0.7219
Loa Loa (eye worm) beta-tubulin 0.1643 0.499 0.7219
Trypanosoma brucei beta tubulin 0.1643 0.499 1
Loa Loa (eye worm) hypothetical protein 0.0093 0.0233 0.0336
Leishmania major epsilon tubulin, putative 0.0941 0.2835 0.5681
Onchocerca volvulus Huntingtin homolog 0.0386 0.113 0.5017
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.006 0.013 0.0189
Leishmania major metallo-beta-lactamase family protein-like protein 0.003 0.004 0.0081
Brugia malayi glutathione reductase 0.0096 0.024 0.0347
Echinococcus granulosus ATP binding cassette subfamily B MDR:TAP 0.0021 0.0013 0.002
Toxoplasma gondii 6-phosphofructokinase 0.003 0.0039 0.0078
Brugia malayi metallo-beta-lactamase superfamily protein 0.003 0.004 0.0058
Brugia malayi hypothetical protein 0.0085 0.0208 0.0301
Trichomonas vaginalis esterase, putative 0.0088 0.0218 0.0437
Toxoplasma gondii Kazal-type serine protease inhibitor domain-containing protein 0.0058 0.0125 0.0251
Echinococcus granulosus regulator of G protein signaling 7 0.0043 0.008 0.0125
Trichomonas vaginalis PIKK family atypical protein kinase 0.0068 0.0156 0.0312
Brugia malayi hypothetical protein 0.0236 0.0671 0.0971
Schistosoma mansoni nuclear receptor nhr-48 0.0026 0.0026 0.0041
Trichomonas vaginalis DNA helicase recq, putative 0.0041 0.0074 0.0148
Brugia malayi MH1 domain containing protein 0.0042 0.0076 0.011
Mycobacterium ulcerans esterase/lipase LipP 0.0088 0.0218 0.1803
Entamoeba histolytica hypothetical protein 0.0186 0.0518 0.1037
Echinococcus multilocularis nuclear receptor subfamily 1 group D 0.0034 0.0052 0.0052
Echinococcus granulosus microtubule associated protein 2 0.2083 0.6339 1
Mycobacterium leprae Probable lipase LipE 0.0088 0.0218 0.1782
Onchocerca volvulus 0.0085 0.0208 0.0923
Echinococcus granulosus NADP dependent isocitrate dehydrogenase 0.0032 0.0044 0.007
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.0088 0.0218 0.1803
Trypanosoma cruzi metallo-beta-lactamase-like protein, putative 0.003 0.004 0.0081
Trypanosoma brucei zeta tubulin, putative 0.0694 0.2077 0.4163
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0033 0.0049 0.0097
Brugia malayi Steroid receptor seven-up type 2 0.006 0.013 0.0189
Toxoplasma gondii Kazal-type serine protease inhibitor domain-containing protein 0.0058 0.0125 0.0251
Mycobacterium tuberculosis NADPH-dependent mycothiol reductase Mtr 0.0096 0.024 0.1415
Echinococcus multilocularis transfer RNA-Lys 0.0145 0.0393 0.0393
Trichomonas vaginalis inositol monophosphatase, putative 0.0045 0.0084 0.0168
Brugia malayi tailless protein 0.0026 0.0026 0.0037
Echinococcus granulosus multidrug resistance protein 1 0.0021 0.0013 0.002
Schistosoma mansoni jumonji/arid domain-containing protein 0.0064 0.0143 0.0225
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0037 0.006 0.0121
Trypanosoma brucei tubulin gamma chain 0.0941 0.2836 0.5683
Loa Loa (eye worm) phosphatidylinositol 3 0.0091 0.0228 0.033
Echinococcus granulosus tubulin epsilon chain 0.0941 0.2835 0.4472
Trichomonas vaginalis A-type flavoprotein 0.003 0.004 0.0081
Loa Loa (eye worm) follicle stimulating hormone receptor 0.0242 0.0691 0.0999
Brugia malayi steroid hormone receptor 0.006 0.013 0.0189
Schistosoma mansoni regulator of G protein signaling 0.0044 0.0083 0.013
Schistosoma mansoni loxhd1 0.0139 0.0373 0.0588
Mycobacterium tuberculosis Conserved hypothetical protein 0.003 0.004 0.0221
Brugia malayi MH2 domain containing protein 0.0042 0.0076 0.011
Leishmania major hypothetical protein, conserved 0.003 0.004 0.0081
Echinococcus multilocularis thioredoxin glutathione reductase 0.0096 0.024 0.024
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0096 0.0243 0.0383
Trypanosoma brucei dihydrolipoyl dehydrogenase 0.0033 0.0049 0.0097
Trichomonas vaginalis conserved hypothetical protein 0.0411 0.1209 0.2423
Entamoeba histolytica tubulin gamma chain 0.0941 0.2836 0.5683
Echinococcus granulosus tubulin beta 4A class IVa 0.1643 0.499 0.7872
Mycobacterium ulcerans 6-phosphofructokinase 0.0111 0.0288 0.2381
Schistosoma mansoni regulator of G protein signaling 0.0043 0.008 0.0125
Trichomonas vaginalis PIKK family atypical protein kinase 0.0055 0.0115 0.023
Loa Loa (eye worm) abnormal chemotaxis protein 14 0.0085 0.0207 0.0299
Onchocerca volvulus 0.0026 0.0026 0.0114
Mycobacterium ulcerans aldehyde dehydrogenase 0.0061 0.0134 0.1112
Trichomonas vaginalis tubulin beta chain, putative 0.1261 0.3818 0.7652
Echinococcus multilocularis tubulin alpha chain 0.1261 0.3818 0.3818
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0045 0.0084 0.0168
Loa Loa (eye worm) hypothetical protein 0.0182 0.0507 0.0734
Loa Loa (eye worm) hypothetical protein 0.003 0.004 0.0058
Echinococcus multilocularis beta LACTamase domain containing family member 0.0088 0.0218 0.0218
Schistosoma mansoni hypothetical protein 0.003 0.004 0.0063
Loa Loa (eye worm) AGC/GRK/GRK protein kinase 0.0044 0.0082 0.0119
Mycobacterium ulcerans flavoprotein disulfide reductase 0.0033 0.0049 0.0402
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0026 0.0026 0.0026
Trypanosoma cruzi MFS transporter, putative 0.0085 0.0208 0.0417
Echinococcus multilocularis multidrug resistance protein 1 0.0021 0.0013 0.0013
Entamoeba histolytica hypothetical protein 0.0186 0.0518 0.1037
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0096 0.0243 0.0487
Echinococcus granulosus multidrug resistance protein 1 0.0021 0.0013 0.002
Brugia malayi nuclear hormone receptor family member odr-7 0.0026 0.0026 0.0037
Echinococcus multilocularis tubulin delta chain 0.0411 0.1209 0.1209
Trypanosoma brucei alpha tubulin 0.1261 0.3818 0.7652
Trichomonas vaginalis lipid A export ATP-binding/permease protein msba, putative 0.0021 0.0013 0.0025
Brugia malayi Doublecortin family protein 0.0139 0.0373 0.0539
Toxoplasma gondii exonuclease III APE 0.0019 0.0005 0.001
Entamoeba histolytica tyrosyl-DNA phosphodiesterase, putative 0.0066 0.0149 0.0299
Schistosoma mansoni nuclear hormone receptor 0.0026 0.0026 0.0041
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0088 0.0218 0.0315
Echinococcus multilocularis TGF beta signal transducer SmadC 0.0042 0.0076 0.0076
Loa Loa (eye worm) ATP-dependent DNA helicase 0.0029 0.0035 0.0051
Trichomonas vaginalis lipid A export ATP-binding/permease protein msba, putative 0.0021 0.0013 0.0025
Trichomonas vaginalis multidrug resistance protein 1, 2, putative 0.0021 0.0013 0.0025
Brugia malayi multidrug resistance protein 3 0.0021 0.0013 0.0018
Echinococcus multilocularis CREB binding protein 0.0068 0.0155 0.0155
Trichomonas vaginalis PIKK family atypical protein kinase 0.0049 0.0099 0.0198
Echinococcus granulosus tyrosyl DNA phosphodiesterase 1 0.0066 0.0149 0.0235
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.006 0.013 0.0189
Brugia malayi A-kinase anchor protein 10, precursor 0.0043 0.008 0.0115
Loa Loa (eye worm) hypothetical protein 0.0021 0.0012 0.0017
Schistosoma mansoni tyrosyl-DNA phosphodiesterase 0.0066 0.0149 0.0235
Echinococcus granulosus Ataxin 2 N terminaldomain containing protein 0.0046 0.0087 0.0138
Toxoplasma gondii target of rapamycin (TOR), putative 0.0068 0.0156 0.0312
Echinococcus granulosus cytochrome P450 2K1 0.0018 0.0003 0.0005
Onchocerca volvulus 0.0088 0.0218 0.0968
Trichomonas vaginalis 6-phosphofructokinase, putative 0.003 0.0039 0.0078
Trichomonas vaginalis PIKK family atypical protein kinase 0.0091 0.0228 0.0457
Echinococcus multilocularis Polycystic kidney disease protein 0.0139 0.0373 0.0373
Onchocerca volvulus 0.0085 0.0208 0.0923
Echinococcus multilocularis nuclear receptor nhr 48 0.0026 0.0026 0.0026
Onchocerca volvulus 0.009 0.0222 0.0987
Brugia malayi Tyrosyl-DNA phosphodiesterase family protein 0.0066 0.0149 0.0216
Trichomonas vaginalis regulator of G protein signaling 5, rgs5, putative 0.0043 0.008 0.0159
Echinococcus granulosus nuclear receptor 2DBD gamma 0.006 0.013 0.0206
Loa Loa (eye worm) hypothetical protein 0.0085 0.0208 0.0301
Trypanosoma brucei epsilon tubulin 0.0914 0.2752 0.5515
Mycobacterium ulcerans extragenic suppressor protein SuhB 0.0045 0.0084 0.0694
Trypanosoma brucei Phosphatidylinositol 3-kinase tor1 0.0091 0.0228 0.0457
Echinococcus multilocularis ecdysone induced protein 78C 0.006 0.013 0.013
Schistosoma mansoni alpha tubulin 0.1261 0.3818 0.6024
Loa Loa (eye worm) pax transcription factor protein 2 0.024 0.0684 0.099
Schistosoma mansoni phosphatidylinositol 3-and 4-kinase 0.0031 0.0041 0.0065
Echinococcus granulosus RUN 0.0139 0.0373 0.0588
Echinococcus multilocularis hydroxyacylglutathione hydrolase 0.003 0.004 0.004
Loa Loa (eye worm) tubulin alpha 2 0.0347 0.1014 0.1466
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative 0.0019 0.0005 0.001
Trichomonas vaginalis conserved hypothetical protein 0.002 0.0009 0.0019
Loa Loa (eye worm) BEN-1 protein 0.1643 0.499 0.7219
Giardia lamblia Kinase, CMGC MAPK 0.0103 0.0262 0.0515
Mycobacterium ulcerans cytochrome P450 150A6 Cyp150A6 0.0018 0.0003 0.0026
Wolbachia endosymbiont of Brugia malayi cell division protein FtsZ 0.0411 0.1209 1
Trichomonas vaginalis conserved hypothetical protein 0.003 0.004 0.0081
Brugia malayi CHE-14 protein 0.0085 0.0207 0.0299
Loa Loa (eye worm) tubulin beta-1 chain 0.1643 0.499 0.7219
Schistosoma mansoni inositol monophosphatase 0.0045 0.0084 0.0132
Trichomonas vaginalis tubulin beta chain, putative 0.1261 0.3818 0.7652
Loa Loa (eye worm) hypothetical protein 0.0082 0.0197 0.0286
Schistosoma mansoni multidrug resistance protein 0.0021 0.0013 0.002
Echinococcus granulosus retinoic acid receptor rxr beta a 0.006 0.013 0.0206
Trichomonas vaginalis tubulin beta chain, putative 0.0503 0.149 0.2986
Brugia malayi Nuclear hormone receptor-like 1 0.006 0.013 0.0189
Trypanosoma cruzi Lanosterol 14-alpha demethylase 0.0018 0.0003 0.0006
Trichomonas vaginalis conserved hypothetical protein 0.0051 0.0104 0.0208
Toxoplasma gondii ABC transporter transmembrane region domain-containing protein 0.0021 0.0013 0.0025
Mycobacterium ulcerans dihydrolipoamide dehydrogenase 0.0033 0.0049 0.0402
Trichomonas vaginalis conserved hypothetical protein 0.002 0.0009 0.0019
Mycobacterium leprae Probable fructose bisphosphate aldolase Fba 0.016 0.0437 0.3601
Trichomonas vaginalis conserved hypothetical protein 0.002 0.0009 0.0019
Echinococcus multilocularis Niemann Pick C1 protein 0.0197 0.0553 0.0553
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.006 0.013 0.0206
Chlamydia trachomatis dihydrolipoyl dehydrogenase 0.0033 0.0049 0.2102
Schistosoma mansoni inositol monophosphatase 0.0045 0.0084 0.0132
Echinococcus multilocularis Transcription factor, JmjC domain containing protein 0.0059 0.0127 0.0127
Brugia malayi hypothetical protein 0.003 0.004 0.0058
Echinococcus multilocularis tubulin alpha chain 0.1261 0.3818 0.3818
Entamoeba histolytica hypothetical protein, conserved 0.003 0.004 0.0081
Leishmania major beta tubulin 0.1643 0.499 1
Leishmania major beta tubulin 0.1643 0.499 1
Mycobacterium ulcerans sugar phosphate isomerases/epimerases 0.002 0.0009 0.0077
Leishmania major phosphopantetheinyl transferase-like protein 0.0026 0.0027 0.0055
Onchocerca volvulus Huntingtin homolog 0.0386 0.113 0.5017
Echinococcus multilocularis mothers against decapentaplegic 6 0.0019 0.0005 0.0005
Schistosoma mansoni 6-phosphofructokinase 0.0111 0.0288 0.0454
Schistosoma mansoni tubulin subunit beta 0.1643 0.499 0.7872
Schistosoma mansoni steroid hormone receptor ad4bp 0.006 0.013 0.0206
Trypanosoma brucei isocitrate dehydrogenase, putative 0.0032 0.0044 0.0089
Brugia malayi sodium-independent organic anion transporter family protein 0.0085 0.0208 0.0301
Echinococcus multilocularis mixed lineage leukemia protein mll 0.0026 0.0026 0.0026
Brugia malayi tubulin alpha-2 chain 0.1261 0.3818 0.5524
Schistosoma mansoni lipoxygenase 0.0577 0.1719 0.2712
Trichomonas vaginalis phosphofructokinase, putative 0.003 0.0039 0.0078
Mycobacterium ulcerans hypothetical protein 0.0088 0.0218 0.1803
Echinococcus granulosus smad 0.0042 0.0076 0.012
Brugia malayi hypothetical protein 0.0043 0.008 0.0115
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0186 0.0518 0.0816
Leishmania major isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0032 0.0044 0.0089
Trichomonas vaginalis conserved hypothetical protein 0.003 0.004 0.0081
Trichomonas vaginalis PIKK family atypical protein kinase 0.0049 0.0099 0.0198
Mycobacterium ulcerans cytochrome P450 189A7 Cyp189A7 0.0018 0.0003 0.0026
Trypanosoma brucei cleavage and polyadenylation specificity factor subunit, putative 0.003 0.004 0.0081
Entamoeba histolytica tubulin alpha-1 chain 0.1261 0.3818 0.7652
Brugia malayi Cytochrome P450 family protein 0.0018 0.0003 0.0005
Echinococcus multilocularis ATP dependent DNA helicase Q1 0.0029 0.0035 0.0035
Trichomonas vaginalis PIKK family atypical protein kinase 0.0049 0.0099 0.0198
Loa Loa (eye worm) RecQ helicase 0.0041 0.0074 0.0107
Brugia malayi PXA domain containing protein 0.0043 0.008 0.0115
Schistosoma mansoni niemann-pick C1 (NPC1) 0.02 0.0562 0.0886
Brugia malayi Nuclear hormone receptor family member nhr-40 0.006 0.013 0.0189
Plasmodium vivax glutathione reductase, putative 0.0096 0.024 0.0481
Loa Loa (eye worm) hypothetical protein 0.0019 0.0006 0.0009
Loa Loa (eye worm) hypothetical protein 0.0759 0.2275 0.3292
Schistosoma mansoni hypothetical protein 0.003 0.004 0.0063
Loa Loa (eye worm) kazal-type serine protease inhibitor domain-containing protein 0.0058 0.0125 0.0181
Trichomonas vaginalis set domain proteins, putative 0.0751 0.2252 0.4514
Mycobacterium tuberculosis Probable lipase LipD 0.0088 0.0218 0.1283
Loa Loa (eye worm) hypothetical protein 0.0197 0.0553 0.0799
Trichomonas vaginalis conserved hypothetical protein 0.0043 0.008 0.0159
Echinococcus granulosus CREB binding protein 0.0061 0.0134 0.0212
Brugia malayi hypoxia-induced factor 1 0.0608 0.1814 0.2624
Mycobacterium leprae PROBABLE ENDONUCLEASE IV END (ENDODEOXYRIBONUCLEASE IV) (APURINASE) 0.0077 0.0184 0.1497
Echinococcus multilocularis lipoxygenase domain containing protein 0.0139 0.0373 0.0373
Echinococcus multilocularis neuropeptide s receptor 0.0931 0.2804 0.2804
Trypanosoma brucei hypothetical protein, conserved 0.0088 0.0218 0.0437
Trypanosoma cruzi mitogen activated protein kinase 2, putative 0.0103 0.0262 0.0524
Loa Loa (eye worm) hypothetical protein 0.0085 0.0208 0.0301
Mycobacterium ulcerans hydrolase 0.003 0.004 0.0333
Leishmania major beta tubulin 0.1643 0.499 1
Brugia malayi MH2 domain containing protein 0.0616 0.1837 0.2658
Trypanosoma brucei beta tubulin 0.1643 0.499 1
Brugia malayi hypothetical protein 0.0386 0.113 0.1635
Trichomonas vaginalis PIKK family atypical protein kinase 0.0031 0.0041 0.0083
Loa Loa (eye worm) 6-phosphofructokinase 0.0111 0.0288 0.0416
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0096 0.0243 0.0243
Loa Loa (eye worm) hypothetical protein 0.0038 0.0063 0.0092
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.002 0.0009 0.0019
Schistosoma mansoni dihydrolipoamide dehydrogenase 0.0033 0.0049 0.0077
Loa Loa (eye worm) hypothetical protein 0.0102 0.026 0.0375
Mycobacterium ulcerans cytochrome P450 125A7 Cyp125A7 0.0018 0.0003 0.0026
Plasmodium falciparum isocitrate dehydrogenase [NADP], mitochondrial 0.0032 0.0044 0.0089
Brugia malayi nuclear receptor NHR-88 0.006 0.013 0.0189
Mycobacterium ulcerans cytochrome P450 187A5 Cyp187A5 0.0018 0.0003 0.0026
Echinococcus multilocularis Ataxin 2, N terminal,domain containing protein 0.0046 0.0087 0.0087
Trichomonas vaginalis CMGC family protein kinase 0.0103 0.0262 0.0524
Trichomonas vaginalis ATP-binding cassette transporter, putative 0.0021 0.0013 0.0025
Mycobacterium ulcerans exodeoxyribonuclease III protein XthA 0.0019 0.0005 0.0042
Trypanosoma cruzi mitogen activated protein kinase 4, putative 0.0103 0.0262 0.0524
Loa Loa (eye worm) tubulin alpha chain 0.1261 0.3818 0.5524
Brugia malayi dihydrolipoyl dehydrogenase, mitochondrial precursor, putative 0.0033 0.0049 0.007
Schistosoma mansoni cytochrome P450 0.0018 0.0003 0.0005
Giardia lamblia Beta tubulin 0.1643 0.499 1
Trypanosoma cruzi PAB1-binding protein , putative 0.0102 0.026 0.052
Echinococcus granulosus dnaJ subfamily B 0.082 0.2462 0.3885
Giardia lamblia Alpha-tubulin 0.1261 0.3818 0.7649
Schistosoma mansoni DNA helicase recq5 0.0029 0.0035 0.0055
Entamoeba histolytica metallo-beta-lactamase superfamily protein 0.003 0.004 0.0081
Plasmodium vivax unspecified product 0.003 0.004 0.0081
Brugia malayi nuclear hormone receptor 0.006 0.013 0.0189
Mycobacterium ulcerans aldehyde dehydrogenase 0.0061 0.0134 0.1112
Brugia malayi nuclear receptor RXR 0.0034 0.0052 0.0075
Brugia malayi Intermediate filament tail domain containing protein 0.0082 0.0197 0.0286
Plasmodium falciparum AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0019 0.0005 0.001
Chlamydia trachomatis two component regulatory system sensor histidine kinase 0.0051 0.0104 0.5329
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.0327 0.0951 0.1906
Brugia malayi cytoplasmic intermediate filament protein 0.0044 0.0081 0.0117
Trichomonas vaginalis PIKK family atypical protein kinase 0.0073 0.017 0.0341
Mycobacterium tuberculosis Probable endonuclease IV End (endodeoxyribonuclease IV) (apurinase) 0.0077 0.0184 0.1077
Giardia lamblia Metallo-beta-lactamase superfamily protein 0.003 0.004 0.0071
Plasmodium vivax ataxin-2 like protein, putative 0.0102 0.026 0.052
Brugia malayi nuclear receptor NHR-67 0.0026 0.0026 0.0037
Echinococcus granulosus axis inhibition protein axin 0.0043 0.008 0.0125
Trichomonas vaginalis penicillin-binding protein, putative 0.0088 0.0218 0.0437
Trichomonas vaginalis tubulin epsilon chain, putative 0.1643 0.499 1
Plasmodium falciparum ataxin-2 like protein, putative 0.0102 0.026 0.052
Loa Loa (eye worm) hypothetical protein 0.006 0.013 0.0189
Trichomonas vaginalis phosphofructokinase, putative 0.0111 0.0288 0.0577
Trichomonas vaginalis ABC transporter, putative 0.0021 0.0013 0.0025
Loa Loa (eye worm) hypothetical protein 0.0088 0.0218 0.0315
Schistosoma mansoni regulator of G protein signaling 0.0043 0.008 0.0125
Brugia malayi MH2 domain containing protein 0.0042 0.0076 0.011
Echinococcus multilocularis Regulator of G protein signaling 20 0.0043 0.008 0.008
Mycobacterium tuberculosis Probable dehydrogenase 0.0218 0.0616 0.3656
Plasmodium vivax tubulin beta chain, putative 0.1643 0.499 1
Trichomonas vaginalis multidrug resistance protein 1, 2, putative 0.0021 0.0013 0.0025
Leishmania major alpha tubulin 0.1261 0.3818 0.7652
Schistosoma mansoni cpg binding protein 0.0095 0.0238 0.0375
Leishmania major alpha tubulin 0.1261 0.3818 0.7652
Trypanosoma brucei beta tubulin 0.0914 0.2752 0.5515
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.0019 0.0005 0.001
Brugia malayi Cell division protein ftsZ 0.0411 0.1209 0.1749
Echinococcus multilocularis Tubulin alpha 1 chain 0.1261 0.3818 0.3818
Echinococcus granulosus tubulin subunit TubB 0.1261 0.3818 0.6024
Loa Loa (eye worm) hypothetical protein 0.0043 0.008 0.0115
Trichomonas vaginalis phosphofructokinase, putative 0.0111 0.0288 0.0577
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0091 0.0228 0.033
Leishmania major mitogen activated protein kinase 4, putative;with=GeneDB:LmxM19.1440 0.0103 0.0262 0.0524
Loa Loa (eye worm) hypothetical protein 0.0043 0.008 0.0115
Loa Loa (eye worm) nuclear hormone receptor-like 1 0.0034 0.0052 0.0075
Brugia malayi mothers against decapentaplegic homolog 3 0.0019 0.0005 0.0007
Loa Loa (eye worm) aryl Hydrocarbon receptor Associated protein family member 0.0051 0.0104 0.015
Trypanosoma cruzi metallo-beta-lactamase superfamily, putative 0.003 0.004 0.0081
Trichomonas vaginalis tubulin beta chain, putative 0.1261 0.3818 0.7652
Entamoeba histolytica P-glycoprotein-1 0.0021 0.0013 0.0025
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.0029 0.0035 0.007
Toxoplasma gondii tubulin/FtsZ family, GTPase domain-containing protein 0.058 0.1728 0.3464
Trypanosoma brucei glyoxalase II 0.003 0.004 0.0081
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0033 0.0049 0.0097
Trichomonas vaginalis tubulin, putative 0.1643 0.499 1
Leishmania major beta tubulin 0.1643 0.499 1
Mycobacterium leprae conserved hypothetical protein 0.003 0.004 0.0307
Loa Loa (eye worm) hypothetical protein 0.0026 0.0026 0.0037
Plasmodium falciparum tubulin beta chain 0.1643 0.499 1
Mycobacterium leprae conserved hypothetical protein 0.002 0.0009 0.0051
Brugia malayi hypothetical protein 0.0026 0.0026 0.0037
Schistosoma mansoni z-protein (S1r protein) 0.0043 0.008 0.0125
Brugia malayi Pre-SET motif family protein 0.066 0.1973 0.2855
Echinococcus granulosus Solute carrier organic anion transporter family 0.0085 0.0208 0.0328
Trichomonas vaginalis conserved hypothetical protein 0.002 0.0009 0.0019
Trichomonas vaginalis PIKK family atypical protein kinase 0.0049 0.0099 0.0198
Echinococcus multilocularis bloom syndrome protein 0.0041 0.0074 0.0074
Schistosoma mansoni smad 0.0042 0.0076 0.012
Schistosoma mansoni rab6-interacting 0.0139 0.0373 0.0588
Entamoeba histolytica P-glycoprotein-2 0.0021 0.0013 0.0025
Echinococcus granulosus regulator of G protein signaling 3 0.0043 0.008 0.0125
Echinococcus granulosus expressed protein 0.075 0.2249 0.3549
Echinococcus granulosus bloom syndrome protein 0.0041 0.0074 0.0116
Mycobacterium ulcerans 4'-phosphopantetheinyl transferase 0.0026 0.0027 0.0226
Brugia malayi Tubulin beta chain 0.0411 0.1209 0.1749
Trichomonas vaginalis conserved hypothetical protein 0.002 0.0009 0.0019
Brugia malayi beta-lactamase family protein 0.0088 0.0218 0.0315
Echinococcus granulosus nuclear receptor nhr 48 0.0026 0.0026 0.0041
Trypanosoma cruzi hydroxyacylglutathione hydrolase, putative 0.003 0.004 0.0081
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0327 0.0951 0.1906
Echinococcus granulosus leukotriene A 4 hydrolase 0.0325 0.0944 0.1489
Mycobacterium tuberculosis Conserved protein 0.0088 0.0218 0.1283
Schistosoma mansoni leukotriene A4 hydrolase (M01 family) 0.0325 0.0944 0.1489
Trypanosoma cruzi trypanothione reductase, putative 0.0096 0.024 0.0481
Loa Loa (eye worm) hypothetical protein 0.0021 0.0013 0.0018
Mycobacterium leprae POSSIBLE HYDROLASE 0.003 0.004 0.0307
Brugia malayi alpha-tubulin 0.1261 0.3818 0.5524
Mycobacterium ulcerans phosphopantetheinyl transferase, PptII 0.0026 0.0027 0.0226
Echinococcus multilocularis zinc phosphodiesterase 0.003 0.004 0.004
Trypanosoma cruzi isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0032 0.0044 0.0089
Mycobacterium ulcerans cytochrome P450 124A1, Cyp124A1 0.0018 0.0003 0.0026
Trichomonas vaginalis PIKK family atypical protein kinase 0.0073 0.017 0.0341
Trichomonas vaginalis tubulin, putative 0.0503 0.149 0.2986
Loa Loa (eye worm) hypothetical protein 0.0037 0.006 0.0087
Loa Loa (eye worm) hypothetical protein 0.0027 0.0031 0.0044
Echinococcus granulosus tubulin alpha 3 chain 0.1261 0.3818 0.6024
Loa Loa (eye worm) steroid hormone receptor 0.006 0.013 0.0189
Treponema pallidum diphosphate--fructose-6-phosphate 1-phosphotransferase 0.003 0.0039 0.0283
Onchocerca volvulus 0.0026 0.0026 0.0114
Trichomonas vaginalis mercuric reductase, putative 0.0033 0.0049 0.0097
Onchocerca volvulus 0.0085 0.0208 0.0923
Leishmania major cleavage and polyadenylation specificity factor, putative 0.003 0.004 0.0081
Leishmania major alpha tubulin 0.1261 0.3818 0.7652
Brugia malayi hypothetical protein 0.0208 0.0584 0.0845
Echinococcus multilocularis regulator of G protein signaling 3 0.0043 0.008 0.008
Toxoplasma gondii beta-tubulin, putative 0.1643 0.499 1
Leishmania major beta tubulin 0.1643 0.499 1
Trichomonas vaginalis conserved hypothetical protein 0.002 0.0009 0.0019
Toxoplasma gondii ATP-binding cassette transporter ABC.B1 0.0021 0.0013 0.0025
Trypanosoma brucei ubiquitin carboxyl-terminal hydrolase, putative 0.0037 0.006 0.0121
Leishmania major ATP-dependent phosphofructokinase 0.0111 0.0288 0.0577
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.0019 0.0005 0.0005
Loa Loa (eye worm) cytochrome P450 0.0018 0.0003 0.0005
Leishmania major hypothetical protein, conserved 0.0088 0.0218 0.0437
Echinococcus granulosus Tubulin beta 2C chain 0.1643 0.499 0.7872
Brugia malayi ATP-dependent DNA helicase, RecQ family protein 0.0029 0.0035 0.0051
Mycobacterium tuberculosis Putative ferredoxin reductase 0.0218 0.0616 0.3656
Onchocerca volvulus 0.0082 0.0197 0.0876
Brugia malayi photoreceptor-specific nuclear receptor 0.006 0.013 0.0189
Echinococcus multilocularis Tubulin alpha 1 chain 0.1261 0.3818 0.3818
Schistosoma mansoni serine/threonine protein kinase 0.0044 0.0082 0.013
Schistosoma mansoni smad1 5 8 and 0.0042 0.0076 0.012
Mycobacterium ulcerans cytochrome P450 142A3 Cyp142A3 0.0018 0.0003 0.0026
Trichomonas vaginalis multidrug resistance protein 1, 2, putative 0.0021 0.0013 0.0025
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0194 0.0542 0.0854
Wolbachia endosymbiont of Brugia malayi metallo-beta-lactamase superfamily hydrolase 0.003 0.004 0.0292
Trichomonas vaginalis conserved hypothetical protein 0.0411 0.1209 0.2423
Schistosoma mansoni CREB-binding protein 2 0.0099 0.025 0.0395
Schistosoma mansoni cellular tumor antigen P53 0.015 0.0408 0.0643
Schistosoma mansoni follistatin 0.0058 0.0125 0.0198
Trichomonas vaginalis beta lactamase domain, putative 0.003 0.004 0.0081
Echinococcus granulosus Tubulin beta 2C chain 0.1643 0.499 0.7872
Brugia malayi 6-phosphofructokinase 0.0111 0.0288 0.0416
Chlamydia trachomatis endonuclease IV 0.0077 0.0184 1
Brugia malayi cytochrome P450 0.0018 0.0003 0.0005
Trypanosoma brucei hydroxyacylglutathione hydrolase, putative 0.003 0.004 0.0081
Brugia malayi Tubulin beta chain 0.0503 0.149 0.2155
Leishmania major cytochrome p450-like protein 0.0018 0.0003 0.0006
Loa Loa (eye worm) beta-lactamase 0.0088 0.0218 0.0315
Echinococcus multilocularis Tubulin alpha 1 chain 0.1261 0.3818 0.3818
Echinococcus multilocularis peroxisome assembly protein 26 0.1261 0.3818 0.3818
Brugia malayi Hypothetical 29.7 kDa protein C05D11.5 in chromosome III 0.002 0.0009 0.0013
Trypanosoma brucei epsilon tubulin 0.0941 0.2835 0.5681
Brugia malayi Niemann-Pick C1 protein precursor 0.0197 0.0553 0.0799
Brugia malayi Kazal-type serine protease inhibitor domain containing protein 0.0058 0.0125 0.0181
Trichomonas vaginalis PIKK family atypical protein kinase 0.0078 0.0187 0.0374
Brugia malayi TAZ zinc finger family protein 0.0099 0.025 0.0362
Loa Loa (eye worm) hypothetical protein 0.0139 0.0373 0.0539
Loa Loa (eye worm) PXA domain-containing protein 0.0043 0.008 0.0115
Echinococcus granulosus aldehyde dehydrogenase mitochondrial 0.0061 0.0134 0.0212
Schistosoma mansoni lamin 0.0082 0.0197 0.0311
Trichomonas vaginalis tubulin, putative 0.0439 0.1293 0.2591
Onchocerca volvulus 0.0503 0.149 0.6614
Trichomonas vaginalis ap endonuclease, putative 0.0019 0.0005 0.001
Loa Loa (eye worm) tubulin alpha 2 0.085 0.2556 0.3698
Onchocerca volvulus 0.0751 0.2253 1
Echinococcus multilocularis raf serine:threonine protein kinase 0.0044 0.0082 0.0082
Echinococcus granulosus nuclear receptor subfamily 1 group D 0.0034 0.0052 0.0081
Trypanosoma cruzi ATP-dependent DEAD/H DNA helicase recQ, putative 0.0031 0.0043 0.0086
Loa Loa (eye worm) isocitrate dehydrogenase 0.0032 0.0044 0.0064
Loa Loa (eye worm) RGS-3 protein 0.0043 0.008 0.0115
Loa Loa (eye worm) hypothetical protein 0.006 0.013 0.0189
Schistosoma mansoni hydroxyacylglutathione hydrolase (Glyoxalase II) (Glx II) 0.003 0.004 0.0063
Plasmodium vivax tubulin gamma chain, putative 0.0941 0.2836 0.5683
Trichomonas vaginalis adenylate and guanylate cyclases, putative 0.0051 0.0104 0.0208
Echinococcus multilocularis RUN 0.0139 0.0373 0.0373
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0033 0.0049 0.0097
Loa Loa (eye worm) hypothetical protein 0.0088 0.0218 0.0315
Leishmania major target of rapamycin kinase (TOR) kinase 3 0.0073 0.0171 0.0342
Entamoeba histolytica P-glycoprotein-2, putative 0.0021 0.0013 0.0025
Trypanosoma cruzi zeta tubulin, putative 0.0694 0.2077 0.4163
Schistosoma mansoni intermediate filament proteins 0.0082 0.0197 0.0311
Plasmodium falciparum thioredoxin reductase 0.0033 0.0049 0.0097
Loa Loa (eye worm) hypothetical protein 0.0085 0.0207 0.0299
Leishmania major hypothetical protein, conserved 0.0102 0.026 0.052
Echinococcus granulosus tumor protein p63 0.1025 0.3093 0.488
Loa Loa (eye worm) histone methyltransferase 0.0031 0.0043 0.0062
Brugia malayi CXXC zinc finger family protein 0.009 0.0222 0.0322
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0327 0.0951 0.1906
Onchocerca volvulus 0.0145 0.0393 0.1746
Echinococcus granulosus arachidonate 5 lipoxygenase 0.0577 0.1719 0.2712
Schistosoma mansoni hypothetical protein 0.0875 0.2634 0.4155
Trypanosoma cruzi glyoxalase II 0.003 0.004 0.0081
Loa Loa (eye worm) hypothetical protein 0.0026 0.0026 0.0037
Leishmania major ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative 0.0037 0.006 0.0121
Trypanosoma cruzi phosphatidylinositol 3-related kinase, putative 0.0031 0.0041 0.0083
Echinococcus granulosus Peptidase C19 ubiquitin carboxyl terminal hydrolase 2 0.0037 0.006 0.0095
Trichomonas vaginalis PIKK family atypical protein kinase 0.0054 0.0113 0.0227
Schistosoma mansoni serine/threonine protein kinase 0.0044 0.0082 0.013
Echinococcus granulosus beta tubulin 0.1643 0.499 0.7872
Mycobacterium tuberculosis Conserved protein 0.003 0.004 0.0221
Schistosoma mansoni hypothetical protein 0.003 0.004 0.0063
Loa Loa (eye worm) tubulin alpha-3 chain 0.0759 0.2275 0.3292
Echinococcus multilocularis Tubulin beta 2C chain 0.1643 0.499 0.499
Entamoeba histolytica P-glyco protein 6, putative 0.0021 0.0013 0.0025
Loa Loa (eye worm) jmjC domain-containing protein 0.0064 0.0143 0.0207
Loa Loa (eye worm) hypothetical protein 0.0058 0.0125 0.0181
Echinococcus granulosus tubulin beta 1 chain 0.1643 0.499 0.7872
Brugia malayi Nuclear hormone receptor family member nhr-19 0.006 0.013 0.0189
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.006 0.013 0.013
Trypanosoma cruzi tubulin delta chain 0.058 0.1728 0.3464
Trichomonas vaginalis adenylate and guanylate cyclases, putative 0.0051 0.0104 0.0208
Leishmania major apurinic/apyrimidinic endonuclease-redox protein 0.0019 0.0005 0.001
Brugia malayi regulator of G-protein signaling egl-10 0.0043 0.008 0.0115
Echinococcus multilocularis Niemann Pick C1 protein 0.0282 0.0812 0.0812
Schistosoma mansoni hypothetical protein 0.0267 0.0766 0.1208
Trichomonas vaginalis lipid A export ATP-binding/permease protein msba, putative 0.0021 0.0013 0.0025
Trypanosoma brucei tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0066 0.0149 0.0299
Schistosoma mansoni DNA helicase recq1 0.0029 0.0035 0.0055
Toxoplasma gondii isocitrate dehydrogenase 0.0032 0.0044 0.0089
Echinococcus granulosus CREB binding protein 0.0099 0.025 0.0395
Mycobacterium ulcerans cytochrome P450 185A4 Cyp185A4 0.0055 0.0115 0.095
Echinococcus multilocularis dihydrolipoamide dehydrogenase 0.0033 0.0049 0.0049
Schistosoma mansoni nuclear receptor 0.0026 0.0026 0.0041
Trypanosoma cruzi tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0066 0.0149 0.0299
Brugia malayi hypothetical protein 0.0182 0.0507 0.0734
Entamoeba histolytica alkyl sulfatase, putative 0.003 0.004 0.0081
Loa Loa (eye worm) hypothetical protein 0.0039 0.0068 0.0098
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.0327 0.0951 0.1906
Trichomonas vaginalis lipid A export ATP-binding/permease protein msba, putative 0.0021 0.0013 0.0025
Trypanosoma cruzi Phosphatidylinositol 3-kinase tor2 0.0091 0.0228 0.0457
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0033 0.0049 0.0097
Leishmania major alpha tubulin 0.1261 0.3818 0.7652
Schistosoma mansoni jumonji/arid domain-containing protein 0.0064 0.0143 0.0225
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0088 0.0218 0.0315
Echinococcus multilocularis Peptidase C19, ubiquitin carboxyl terminal hydrolase 2 0.0037 0.006 0.006
Toxoplasma gondii transporter, major facilitator family protein 0.0085 0.0208 0.0417
Echinococcus multilocularis ATP dependent DNA helicase Q5 0.0029 0.0035 0.0035
Leishmania major beta tubulin 0.1643 0.499 1
Plasmodium falciparum tubulin epsilon chain, putative 0.0941 0.2835 0.5681
Leishmania major metallo-beta-lactamase family-like protein 0.003 0.004 0.0081
Mycobacterium tuberculosis Cell division protein FtsZ 0.0411 0.1209 0.7198
Toxoplasma gondii tubulin/FtsZ family, GTPase domain-containing protein 0.0438 0.1292 0.2589
Trypanosoma cruzi PAS-domain containing phosphoglycerate kinase, putative 0.0051 0.0104 0.0208
Echinococcus multilocularis dnaJ subfamily B 0.082 0.2462 0.2462
Trypanosoma brucei protein kinase, putative 0.0103 0.0262 0.0524
Loa Loa (eye worm) agrin synaptic family protein 0.0058 0.0125 0.0181
Plasmodium falciparum ATP-dependent 6-phosphofructokinase 0.003 0.0039 0.0078
Toxoplasma gondii Kazal-type serine protease inhibitor domain-containing protein 0.0058 0.0125 0.0251
Plasmodium falciparum cytosolic glyoxalase II 0.003 0.004 0.0081
Brugia malayi ABC transporter family protein 0.0021 0.0013 0.0018
Brugia malayi jmjC domain containing protein 0.0064 0.0143 0.0207
Loa Loa (eye worm) hypothetical protein 0.0659 0.197 0.2851
Echinococcus granulosus tubulin alpha 1C chain 0.1261 0.3818 0.6024
Echinococcus multilocularis arachidonate 5 lipoxygenase 0.0577 0.1719 0.1719
Brugia malayi hypothetical protein 0.0139 0.0373 0.0539
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.006 0.013 0.013
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0037 0.006 0.0121
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0033 0.0049 0.0097
Onchocerca volvulus Bile acid receptor homolog 0.006 0.013 0.0579
Schistosoma mansoni ap endonuclease 0.0019 0.0005 0.0008
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.0048 0.0095 0.0137
Brugia malayi prostaglandin transporter 0.0085 0.0208 0.0301
Loa Loa (eye worm) tubulin beta-2A chain 0.1643 0.499 0.7219
Entamoeba histolytica type A flavoprotein, putative 0.003 0.004 0.0081
Echinococcus multilocularis tubulin gamma 1 chain 0.0941 0.2836 0.2836
Schistosoma mansoni agrin 0.0058 0.0125 0.0198
Schistosoma mansoni cpg binding protein 0.0095 0.0238 0.0375
Schistosoma mansoni tubulin subunit epsilon 0.0941 0.2835 0.4472
Schistosoma mansoni organic anion transporter 0.0085 0.0208 0.0328
Echinococcus granulosus mothers against decapentaplegic 6 0.0019 0.0005 0.0007
Echinococcus multilocularis tubulin alpha 1C chain 0.1261 0.3818 0.3818
Echinococcus multilocularis aryl hydrocarbon receptor 0.0051 0.0104 0.0104
Trichomonas vaginalis conserved hypothetical protein 0.0085 0.0207 0.0415
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.006 0.013 0.013
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.006 0.013 0.013
Entamoeba histolytica tubulin family protein 0.1643 0.499 1
Trichomonas vaginalis lipid A export ATP-binding/permease protein msba, putative 0.0021 0.0013 0.0025
Echinococcus multilocularis FKBP12 rapamycin complex associated protein 0.0091 0.0228 0.0228
Mycobacterium ulcerans hydrolase 0.003 0.004 0.0333
Schistosoma mansoni serine/threonine protein kinase 0.0044 0.0082 0.013
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.0029 0.0035 0.007
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0033 0.0049 0.0097
Giardia lamblia Alpha-tubulin 0.1261 0.3818 0.7649
Schistosoma mansoni tubulin subunit beta 0.0411 0.1209 0.1907
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 8 0.0037 0.006 0.0095
Brugia malayi hypothetical protein 0.0026 0.0026 0.0037
Echinococcus granulosus tubulin subunit beta 0.1643 0.499 0.7872
Schistosoma mansoni thyroid hormone receptor 0.006 0.013 0.0206
Echinococcus granulosus inositol monophosphatase 1 0.0045 0.0084 0.0132
Plasmodium vivax thioredoxin reductase, putative 0.0096 0.024 0.0481
Echinococcus granulosus FKBP12 rapamycin complex associated protein 0.0091 0.0228 0.0359
Echinococcus multilocularis multidrug resistance protein 1 0.0021 0.0013 0.0013
Loa Loa (eye worm) hypothetical protein 0.0085 0.0208 0.0301
Brugia malayi secreted modular calcium-binding protein 1 0.0058 0.0125 0.0181
Mycobacterium ulcerans cytochrome P450 143A3 Cyp143A3 0.0018 0.0003 0.0026
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0096 0.0243 0.0243
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0088 0.0218 0.0344
Loa Loa (eye worm) MH1 domain-containing protein 0.0042 0.0076 0.011
Onchocerca volvulus 0.0182 0.0507 0.2251
Trichomonas vaginalis tubulin alpha chain, putative 0.0503 0.149 0.2986
Echinococcus multilocularis organic anion transporting polypeptide 30B 0.0085 0.0208 0.0208
Mycobacterium ulcerans cytochrome P450 51B1 Cyp51B1 0.0018 0.0003 0.0026
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0327 0.0951 0.1906
Mycobacterium ulcerans cytochrome P450 143A4 Cyp143A4 0.0018 0.0003 0.0026
Trichomonas vaginalis guanylate cyclase, putative 0.0051 0.0104 0.0208
Echinococcus granulosus Tubulin alpha 1 chain 0.1261 0.3818 0.6024
Echinococcus granulosus Tubulin alpha 1 chain 0.1261 0.3818 0.6024
Loa Loa (eye worm) hypothetical protein 0.0021 0.0013 0.0018
Trichomonas vaginalis PIKK family atypical protein kinase 0.0073 0.017 0.0341
Wolbachia endosymbiont of Brugia malayi dihydrolipoamide dehydrogenase E3 component 0.0033 0.0049 0.0362
Echinococcus multilocularis Solute carrier organic anion transporter family 0.0085 0.0208 0.0208
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0026 0.0026 0.0041
Trichomonas vaginalis tubulin alpha-1 chain, putative 0.0503 0.149 0.2986
Schistosoma mansoni regulator of G protein signaling 3 rgs3 0.0043 0.008 0.0125
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.002 0.0009 0.0019
Echinococcus multilocularis FTZ F1 alpha 0.006 0.013 0.013
Loa Loa (eye worm) nuclear receptor NHR-67 0.0026 0.0026 0.0037
Echinococcus granulosus regulator of G protein signaling 3 0.0043 0.008 0.0125
Leishmania major lanosterol 14-alpha-demethylase, putative 0.0018 0.0003 0.0006
Echinococcus multilocularis tubulin subunit beta 0.1643 0.499 0.499
Brugia malayi phosphofructokinase 0.0111 0.0288 0.0416
Trypanosoma cruzi apurinic/apyrimidinic endonuclease 0.0019 0.0005 0.001
Loa Loa (eye worm) tubulin alpha chain 0.1261 0.3818 0.5524
Loa Loa (eye worm) hypothetical protein 0.0038 0.0063 0.0092
Loa Loa (eye worm) MH1 domain-containing protein 0.0019 0.0005 0.0007
Schistosoma mansoni hypothetical protein 0.0082 0.0198 0.0312
Echinococcus granulosus tubulin delta chain 0.0411 0.1209 0.1907
Entamoeba histolytica P-glycoprotein 5, putative 0.0021 0.0013 0.0025
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription factor 0.0264 0.0758 0.0758
Mycobacterium ulcerans Zn-dependent glyoxylase 0.003 0.004 0.0333
Brugia malayi Regulator of G protein signaling domain containing protein 0.0043 0.008 0.0115
Leishmania major alpha tubulin 0.1261 0.3818 0.7652
Echinococcus multilocularis tubulin alpha 3 chain 0.1261 0.3818 0.3818
Leishmania major beta tubulin 0.1643 0.499 1
Onchocerca volvulus 0.0096 0.0243 0.1078
Mycobacterium ulcerans hypothetical protein 0.002 0.0009 0.0077
Leishmania major cytochrome p450-like protein 0.0018 0.0003 0.0006
Mycobacterium tuberculosis Possible hydrolase 0.003 0.004 0.0221
Trypanosoma cruzi cytochrome P450, putative 0.0055 0.0115 0.023
Trichomonas vaginalis phosphofructokinase, putative 0.0111 0.0288 0.0577
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0045 0.0084 0.0168
Trichomonas vaginalis CMGC family protein kinase 0.0103 0.0262 0.0524
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0026 0.0026 0.0114
Echinococcus granulosus Basic leucine zipper bZIP transcription factor 0.0264 0.0758 0.1196
Echinococcus granulosus Smad4 0.0042 0.0076 0.012
Brugia malayi sodium-independent organic anion transporter family protein 0.0085 0.0208 0.0301
Echinococcus granulosus tubulin alpha chain 0.1261 0.3818 0.6024
Schistosoma mansoni lipoxygenase 0.0328 0.0952 0.1503
Echinococcus granulosus geminin 0.0875 0.2634 0.4155
Leishmania major hydroxyacylglutathione hydrolase, putative,glyoxalase II, putative 0.003 0.004 0.0081
Chlamydia trachomatis fructose-6-phosphate phosphotransferase 0.003 0.0039 0.1546
Echinococcus granulosus histone lysine methyltransferase setb 0.0096 0.0243 0.0383
Loa Loa (eye worm) hypothetical protein 0.0026 0.0026 0.0037
Mycobacterium ulcerans hypothetical protein 0.003 0.004 0.0333
Mycobacterium ulcerans endonuclease IV 0.0077 0.0184 0.1519
Brugia malayi nuclear hormone receptor 0.0026 0.0026 0.0037
Schistosoma mansoni retinoid-x-receptor (RXR) 0.006 0.013 0.0206
Entamoeba histolytica metallo-beta-lactamase superfamily protein 0.003 0.004 0.0081
Mycobacterium ulcerans cytochrome P450 126A3 Cyp126A3 0.0018 0.0003 0.0026
Trypanosoma brucei epsilon tubulin 0.0941 0.2835 0.5681
Trypanosoma brucei beta tubulin 0.1643 0.499 1
Trypanosoma cruzi alpha tubulin, putative 0.1261 0.3818 0.7652
Mycobacterium leprae Beta-lactamase-like protein 0.003 0.004 0.0307
Brugia malayi intermediate filament protein 0.0082 0.0197 0.0286
Trichomonas vaginalis multidrug resistance protein 1, 2, putative 0.0021 0.0013 0.0025
Trichomonas vaginalis conserved hypothetical protein 0.0051 0.0104 0.0208
Brugia malayi Cytochrome P450 family protein 0.0055 0.0115 0.0166
Loa Loa (eye worm) glutathione reductase 0.0096 0.024 0.0347
Treponema pallidum 4'-phosphopantetheinyl transferase 0.0026 0.0027 0.0185
Giardia lamblia Pyrophosphate-fructose 6-phosphate 1-phosphotransferase alpha subunit 0.003 0.0039 0.0068
Trichomonas vaginalis PIKK family atypical protein kinase 0.0068 0.0156 0.0312
Leishmania major alpha tubulin 0.1261 0.3818 0.7652
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.006 0.013 0.0206
Trichomonas vaginalis tubulin beta chain, putative 0.1643 0.499 1
Echinococcus granulosus Transcription factor JmjC domain containing protein 0.0059 0.0127 0.0201
Trichomonas vaginalis tubulin gamma chain, putative 0.0411 0.1209 0.2423
Mycobacterium leprae conserved hypothetical protein 0.0088 0.0218 0.1782
Brugia malayi Tubulin beta-1 chain 0.1643 0.499 0.7219
Echinococcus granulosus mothers against decapentaplegic 5 0.0042 0.0076 0.012
Treponema pallidum cell division protein FtsZ 0.0411 0.1209 1
Loa Loa (eye worm) DR-78 0.0026 0.0026 0.0037
Brugia malayi Kazal-type serine protease inhibitor domain containing protein 0.0058 0.0125 0.0181
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.006 0.013 0.0206
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.002 0.0009 0.0019
Brugia malayi ecdysone receptor 0.0026 0.0026 0.0037
Brugia malayi Nuclear hormone receptor E75 0.0026 0.0026 0.0037
Trichomonas vaginalis conserved hypothetical protein 0.003 0.004 0.0081
Mycobacterium ulcerans cytochrome P450 144A4 Cyp144A4 0.0018 0.0003 0.0026
Loa Loa (eye worm) hypothetical protein 0.003 0.004 0.0058
Loa Loa (eye worm) hypothetical protein 0.0026 0.0026 0.0037
Brugia malayi ethe1-prov protein 0.003 0.004 0.0058
Toxoplasma gondii tubulin, putative 0.0027 0.003 0.006
Loa Loa (eye worm) hypothetical protein 0.002 0.0009 0.0013
Echinococcus multilocularis tubulin alpha 1C chain 0.1261 0.3818 0.3818
Loa Loa (eye worm) hypothetical protein 0.0026 0.0026 0.0037
Loa Loa (eye worm) hypothetical protein 0.0085 0.0208 0.0301
Echinococcus granulosus Aryl hydrocarbon receptor nuclear 0.0051 0.0104 0.0164
Loa Loa (eye worm) hypothetical protein 0.0026 0.0026 0.0037
Trichomonas vaginalis tubulin beta chain, putative 0.1261 0.3818 0.7652
Echinococcus multilocularis aldehyde dehydrogenase, mitochondrial 0.0061 0.0134 0.0134
Plasmodium vivax dihydrolipoyl dehydrogenase, apicoplast, putative 0.0033 0.0049 0.0097
Brugia malayi Tubulin alpha chain 0.1261 0.3818 0.5524
Loa Loa (eye worm) hypothetical protein 0.006 0.013 0.0189
Schistosoma mansoni Smad4 0.0042 0.0076 0.012
Leishmania major aldehyde dehydrogenase, mitochondrial precursor 0.0061 0.0134 0.0269
Loa Loa (eye worm) tubulin beta chain 0.0411 0.1209 0.1749
Echinococcus granulosus agrin 0.0058 0.0125 0.0198
Loa Loa (eye worm) ATP-binding cassette sub-family B member 2 0.0021 0.0013 0.0018
Brugia malayi Pax transcription factor protein 2 0.024 0.0684 0.099
Loa Loa (eye worm) MH2 domain-containing protein 0.0616 0.1837 0.2658
Trichomonas vaginalis tubulin gamma chain, putative 0.1643 0.499 1
Leishmania major beta tubulin 0.1643 0.499 1
Echinococcus granulosus 5'partial|ATP binding cassette sub family B 0.0021 0.0012 0.0019
Brugia malayi nuclear receptor NHR-88 0.0026 0.0026 0.0037
Onchocerca volvulus 0.0058 0.0125 0.0556
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.0088 0.0218 0.1283
Schistosoma mansoni ubiquitin-specific peptidase 2 (C19 family) 0.0037 0.006 0.0095
Loa Loa (eye worm) hypothetical protein 0.0019 0.0005 0.0007
Trypanosoma brucei tubulin delta chain 0.058 0.1728 0.3464
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0026 0.0026 0.0026
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.002 0.0009 0.0019
Echinococcus granulosus transcription factor Dp 1 0.0038 0.0064 0.0101
Schistosoma mansoni hepatocyte nuclear factor 4-alpha (hnf-4-alpha) 0.0026 0.0026 0.0041
Brugia malayi nuclear receptor subfamily 1, group D, member 1, putative 0.0026 0.0026 0.0037
Mycobacterium tuberculosis Probable conserved lipoprotein 0.0088 0.0218 0.1283
Onchocerca volvulus 0.0139 0.0373 0.1655
Loa Loa (eye worm) hypothetical protein 0.085 0.2556 0.3698
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.006 0.013 0.0189
Plasmodium falciparum tubulin delta chain, putative 0.0411 0.1209 0.2423
Brugia malayi hypothetical protein 0.0085 0.0208 0.0301
Treponema pallidum ribonuclease Z 0.003 0.004 0.0292
Entamoeba histolytica Niemann-Pick C1 protein, putative 0.0197 0.0553 0.1107
Trichomonas vaginalis ATP-binding cassette transporter, putative 0.0021 0.0013 0.0025
Echinococcus granulosus cytoplasmic intermediate filament protein 0.0039 0.0068 0.0107
Trichomonas vaginalis conserved hypothetical protein 0.0043 0.008 0.0159
Brugia malayi Nuclear hormone receptor family member nhr-31 0.006 0.013 0.0189
Mycobacterium leprae PROBABLE NADH DEHYDROGENASE NDH 0.0218 0.0616 0.508
Mycobacterium ulcerans cytochrome P450 191A3 Cyp191A3 0.0018 0.0003 0.0026
Brugia malayi hypothetical protein 0.0066 0.0149 0.0215
Schistosoma mansoni transcription factor LCR-F1 0.0186 0.0518 0.0816
Toxoplasma gondii beta-1 tubulin, putative 0.1643 0.499 1
Brugia malayi Nuclear hormone receptor-like 1 0.0034 0.0052 0.0075
Schistosoma mansoni axis inhibition protein axin 0.0043 0.008 0.0125
Brugia malayi Tubulin alpha-2 chain 0.1261 0.3818 0.5524
Schistosoma mansoni multidrug resistance protein 0.0021 0.0013 0.002
Schistosoma mansoni tubulin subunit beta 0.1643 0.499 0.7872
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0045 0.0084 0.0168
Echinococcus granulosus Niemann Pick C1 protein 0.0197 0.0553 0.0872
Giardia lamblia Beta tubulin 0.1643 0.499 1
Schistosoma mansoni ubiquitin-specific peptidase 8 (C19 family) 0.0037 0.006 0.0095
Loa Loa (eye worm) hypothetical protein 0.0026 0.0026 0.0037
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.002 0.0009 0.0019
Entamoeba histolytica pyrophosphate-dependent phosphofructokinase 0.003 0.0039 0.0078
Echinococcus multilocularis ATP binding cassette subfamily B (MDR:TAP) 0.0021 0.0013 0.0013
Echinococcus granulosus ATP dependent DNA helicase Q5 0.0029 0.0035 0.0055
Trichomonas vaginalis ABC transporter, putative 0.0021 0.0013 0.0025
Echinococcus multilocularis ATP binding cassette subfamily B (MDR:TAP) 0.0021 0.0013 0.0013
Trypanosoma brucei alpha tubulin 0.1261 0.3818 0.7652
Brugia malayi Nuclear hormone receptor family member nhr-41 0.006 0.013 0.0189
Onchocerca volvulus 0.0088 0.0218 0.0968
Chlamydia trachomatis fructose-6-phosphate phosphotransferase 0.003 0.0039 0.1546
Echinococcus granulosus lipoxygenase domain containing protein 0.0139 0.0373 0.0588
Plasmodium falciparum thioredoxin reductase 0.0096 0.024 0.0481
Brugia malayi Nuclear hormone receptor family member nhr-3 0.006 0.013 0.0189
Echinococcus multilocularis expressed conserved protein 0.0185 0.0516 0.0516
Mycobacterium tuberculosis Conserved protein 0.003 0.004 0.0221

Activities

Activity type Activity value Assay description Source Reference
Potency (functional) = 5.6234 um PUBCHEM_BIOASSAY: qHTS Assay for Identifying the Cell-Membrane Permeable IMPase Inhibitors. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) 10 uM PUBCHEM_BIOASSAY: qHTS for Inhibitors of Vif-A3F Interactions: qHTS. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) = 28.1838 um PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) = 39.8107 um PUBCHEM_BIOASSAY: qHTS for Inhibitors of Tau Fibril Formation, Fluorescence Polarization. (Class of assay: confirmatory) [Related pubchem assays: 596 ] ChEMBL. No reference

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

No literature references available for this target.

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