Detailed information for compound 1408181

Basic information

Technical information
  • TDR Targets ID: 1408181
  • Name: [5-[(2-methylphenyl)sulfonylmethyl]furan-2-yl ]-(4-pyrimidin-2-ylpiperazin-1-yl)methanone
  • MW: 426.489 | Formula: C21H22N4O4S
  • H donors: 0 H acceptors: 5 LogP: 2.12 Rotable bonds: 6
    Rule of 5 violations (Lipinski): 1
  • SMILES: O=C(c1ccc(o1)CS(=O)(=O)c1ccccc1C)N1CCN(CC1)c1ncccn1
  • InChi: 1S/C21H22N4O4S/c1-16-5-2-3-6-19(16)30(27,28)15-17-7-8-18(29-17)20(26)24-11-13-25(14-12-24)21-22-9-4-10-23-21/h2-10H,11-15H2,1H3
  • InChiKey: GWQLLHKETFNQCK-UHFFFAOYSA-N  


Substructure search Similarity search

Network

Hover on a compound node to display the structore

Synonyms

  • [5-[(2-methylphenyl)sulfonylmethyl]-2-furyl]-(4-pyrimidin-2-ylpiperazin-1-yl)methanone
  • [5-[(2-methylphenyl)sulfonylmethyl]-2-furyl]-[4-(2-pyrimidinyl)-1-piperazinyl]methanone
  • 2-[4-(5-{[(2-methylphenyl)sulfonyl]methyl}-2-furoyl)piperazin-1-yl]pyrimidine
  • MLS000046826
  • SMR000032837

Targets

Known targets for this compound

Species Target name Source Bibliographic reference
Homo sapiens survival of motor neuron 2, centromeric Starlite/ChEMBL No references

Predicted pathogen targets for this compound

By orthology
Species Potential target Known druggable target/s Ortholog Group
Brugia malayi hypothetical protein Get druggable targets OG5_132873 All targets in OG5_132873
Echinococcus granulosus survival motor neuron protein 1 Get druggable targets OG5_132873 All targets in OG5_132873
Echinococcus multilocularis survival motor neuron protein 1 Get druggable targets OG5_132873 All targets in OG5_132873
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_132873 All targets in OG5_132873
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0034 0.0048 0.0096
Schistosoma mansoni smad1 5 8 and 0.0043 0.0076 0.0119
Echinococcus granulosus A kinase anchor protein 10 mitochondrial 0.0044 0.0079 0.0125
Echinococcus granulosus Niemann Pick C1 protein 0.02 0.0552 0.0871
Echinococcus granulosus Tubulin alpha 1 chain 0.1291 0.3847 0.607
Plasmodium vivax tubulin alpha chain, putative 0.1291 0.3847 0.7596
Brugia malayi Cytochrome P450 family protein 0.0068 0.0151 0.0298
Brugia malayi hypothetical protein 0.0286 0.081 0.1599
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.0068 0.0153 0.0241
Trichomonas vaginalis lipid A export ATP-binding/permease protein msba, putative 0.0022 0.0013 0.0025
Trichomonas vaginalis tubulin, putative 0.0516 0.1506 0.2974
Onchocerca volvulus 0.0086 0.0208 0.0905
Schistosoma mansoni microtubule-associated protein tau 0.2116 0.6339 1
Echinococcus multilocularis geminin 0.089 0.2634 0.2634
Treponema pallidum diphosphate--fructose-6-phosphate 1-phosphotransferase 0.0113 0.0288 0.2324
Brugia malayi DNA-(Apurinic or apyrimidinic site) lyase 0.0078 0.0183 0.0362
Trichomonas vaginalis PIKK family atypical protein kinase 0.0055 0.0113 0.0223
Mycobacterium tuberculosis Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB 0.0221 0.0616 0.5019
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0032 0.0044 0.0044
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0034 0.0048 0.0086
Trichomonas vaginalis tubulin beta chain, putative 0.0516 0.1506 0.2974
Mycobacterium tuberculosis NAD(P)H quinone reductase LpdA 0.0246 0.069 0.5633
Mycobacterium ulcerans aldehyde dehydrogenase 0.0062 0.0134 0.1063
Trichomonas vaginalis tubulin beta chain, putative 0.1291 0.3847 0.7598
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0333 0.0952 0.1879
Trichomonas vaginalis PIKK family atypical protein kinase 0.0062 0.0135 0.0267
Loa Loa (eye worm) hypothetical protein 0.0068 0.0153 0.0301
Echinococcus multilocularis protein patched 0.0086 0.0207 0.0207
Trypanosoma cruzi phosphatidylinositol 3-related kinase, putative 0.0031 0.0041 0.0081
Giardia lamblia Pyrophosphate-fructose 6-phosphate 1-phosphotransferase alpha subunit 0.003 0.0039 0.0067
Leishmania major trypanothione reductase 0.0097 0.024 0.0465
Schistosoma mansoni tubulin subunit beta 0.1694 0.5064 0.7989
Entamoeba histolytica hypothetical protein 0.0027 0.0027 0.0054
Echinococcus granulosus tubulin epsilon chain 0.0966 0.2864 0.4518
Loa Loa (eye worm) thioredoxin reductase 0.0097 0.024 0.0474
Echinococcus multilocularis cpg binding protein 0.0096 0.0238 0.0238
Trypanosoma cruzi beta tubulin, putative 0.1694 0.5064 1
Trichomonas vaginalis ATP-binding cassette transporter, putative 0.0022 0.0013 0.0025
Trichomonas vaginalis tubulin beta chain, putative 0.1291 0.3847 0.7598
Echinococcus granulosus retinoic acid receptor rxr beta a 0.0068 0.0153 0.0241
Echinococcus multilocularis Jumonji, AT rich interactive domain 1B 0.0021 0.0011 0.0011
Loa Loa (eye worm) CBP-B 0.0139 0.0366 0.0722
Echinococcus multilocularis Tubulin beta 2C chain 0.1694 0.5064 0.5064
Trypanosoma cruzi PAB1-binding protein , putative 0.0103 0.0259 0.0512
Trypanosoma cruzi isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0032 0.0044 0.0087
Mycobacterium ulcerans dihydrolipoamide dehydrogenase, LpdB 0.0034 0.0048 0.0358
Echinococcus granulosus tubulin alpha chain 0.1291 0.3847 0.607
Brugia malayi Tyrosyl-DNA phosphodiesterase family protein 0.0067 0.0149 0.0294
Loa Loa (eye worm) tubulin beta chain 0.1694 0.5064 1
Trichomonas vaginalis conserved hypothetical protein 0.0044 0.0079 0.0157
Trypanosoma cruzi zeta tubulin, putative 0.0709 0.209 0.4127
Mycobacterium ulcerans 6-phosphofructokinase 0.0113 0.0288 0.2324
Trichomonas vaginalis PIKK family atypical protein kinase 0.0069 0.0156 0.0308
Onchocerca volvulus 0.0095 0.0233 0.1015
Trichomonas vaginalis lipid A export ATP-binding/permease protein msba, putative 0.0022 0.0013 0.0025
Leishmania major epsilon tubulin, putative 0.0966 0.2864 0.5651
Trypanosoma brucei phosphatidylinositol 4-kinase, putative 0.0093 0.0228 0.045
Trypanosoma cruzi epsilon tubulin, putative 0.0966 0.2864 0.5655
Mycobacterium ulcerans cytochrome P450 125A7 Cyp125A7 0.0022 0.0013 0.007
Trypanosoma brucei dihydrolipoyl dehydrogenase 0.0034 0.0048 0.0096
Mycobacterium tuberculosis Cytochrome P450 121 Cyp121 0.0022 0.0013 0.007
Trypanosoma brucei epsilon tubulin 0.0966 0.2864 0.5655
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0333 0.0952 0.1879
Brugia malayi nuclear hormone receptor family member nhr-6 0.003 0.0036 0.0071
Leishmania major beta tubulin 0.1694 0.5064 1
Echinococcus multilocularis lysine specific demethylase 5A 0.006 0.0127 0.0127
Echinococcus granulosus neuropeptide s receptor 0.0946 0.2804 0.4423
Brugia malayi mothers against decapentaplegic homolog 3 0.0019 0.0004 0.0009
Echinococcus multilocularis beta tubulin 0.1694 0.5064 0.5064
Trypanosoma brucei beta tubulin 0.1694 0.5064 1
Schistosoma mansoni hypothetical protein 0.0046 0.0087 0.0137
Trypanosoma brucei epsilon tubulin 0.0938 0.2781 0.5491
Mycobacterium ulcerans cytochrome P450 150A6 Cyp150A6 0.0022 0.0013 0.007
Entamoeba histolytica tubulin family protein 0.1694 0.5064 1
Echinococcus multilocularis tubulin alpha chain 0.1291 0.3847 0.3847
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.0029 0.0035 0.0069
Schistosoma mansoni cpg binding protein 0.0096 0.0238 0.0375
Echinococcus multilocularis Tubulin alpha 1 chain 0.1291 0.3847 0.3847
Brugia malayi SPARC precursor 0.0059 0.0125 0.0247
Echinococcus multilocularis Tubulin beta 2C chain 0.1694 0.5064 0.5064
Brugia malayi Regulator of G protein signaling domain containing protein 0.0044 0.0079 0.0157
Loa Loa (eye worm) hypothetical protein 0.0038 0.0063 0.0125
Leishmania major beta tubulin 0.1694 0.5064 1
Loa Loa (eye worm) hypothetical protein 0.0103 0.0259 0.0512
Brugia malayi Probable G protein-coupled receptor kinase F19C6.1, putative 0.0045 0.0082 0.0162
Echinococcus multilocularis Tubulin alpha 1 chain 0.1291 0.3847 0.3847
Leishmania major alpha tubulin 0.1291 0.3847 0.7596
Loa Loa (eye worm) hypothetical protein 0.0039 0.0063 0.0125
Echinococcus granulosus mitogen activated protein kinase 3 0.0104 0.0262 0.0413
Loa Loa (eye worm) tubulin alpha 2 0.0353 0.1014 0.2002
Mycobacterium tuberculosis Probable dehydrogenase 0.0221 0.0616 0.5019
Giardia lamblia GTOR 0.0093 0.0228 0.044
Leishmania major cytochrome p450-like protein 0.0022 0.0013 0.0017
Toxoplasma gondii phosphofructokinase PFKII 0.003 0.0039 0.0077
Echinococcus multilocularis lipoxygenase domain containing protein 0.016 0.0431 0.0431
Loa Loa (eye worm) cytochrome P450 family protein 0.0068 0.0151 0.0298
Leishmania major cytochrome p450-like protein 0.0022 0.0013 0.0017
Echinococcus multilocularis tubulin beta 1 chain 0.1694 0.5064 0.5064
Echinococcus multilocularis tubulin subunit TubB 0.1291 0.3847 0.3847
Brugia malayi Cytochrome P450 family protein 0.0022 0.0013 0.0027
Loa Loa (eye worm) ATP-dependent DNA helicase 0.0029 0.0035 0.0069
Plasmodium vivax dihydrolipoyl dehydrogenase, apicoplast, putative 0.0034 0.0048 0.0086
Brugia malayi MH2 domain containing protein 0.0043 0.0076 0.0149
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0068 0.0153 0.0301
Loa Loa (eye worm) 6-phosphofructokinase 0.0113 0.0288 0.0568
Trichomonas vaginalis set domain proteins, putative 0.0763 0.2253 0.445
Trichomonas vaginalis adenylate and guanylate cyclases, putative 0.0052 0.0104 0.0205
Brugia malayi Nuclear hormone receptor family member nhr-31 0.0068 0.0153 0.0301
Trypanosoma brucei tubulin delta chain 0.0594 0.1741 0.3438
Brugia malayi follicle stimulating hormone receptor 0.0246 0.0691 0.1364
Leishmania major alpha tubulin 0.1291 0.3847 0.7596
Mycobacterium leprae cell division protein FtsZ 0.0422 0.1221 1
Echinococcus granulosus axis inhibition protein axin 0.0044 0.0079 0.0125
Trypanosoma brucei alpha tubulin 0.1291 0.3847 0.7598
Echinococcus multilocularis expressed protein 0.0059 0.0125 0.0125
Echinococcus multilocularis nuclear receptor subfamily 4 group A 0.003 0.0036 0.0036
Brugia malayi Nuclear hormone receptor-like 1 0.0039 0.0063 0.0125
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.0019 0.0005 0.001
Schistosoma mansoni tubulin subunit beta 0.0422 0.1221 0.1927
Echinococcus granulosus Tubulin beta 2C chain 0.1694 0.5064 0.7989
Loa Loa (eye worm) hypothetical protein 0.0046 0.0084 0.0167
Loa Loa (eye worm) tubulin beta-1 chain 0.1694 0.5064 1
Brugia malayi hypothetical protein 0.0086 0.0208 0.0411
Brugia malayi Cell division protein ftsZ 0.0422 0.1221 0.2412
Chlamydia trachomatis endonuclease IV 0.0078 0.0183 1
Brugia malayi hypothetical protein 0.016 0.0431 0.0851
Brugia malayi hypothetical protein 0.0211 0.0584 0.1153
Brugia malayi Nuclear hormone receptor E75 0.003 0.0036 0.0071
Echinococcus multilocularis mothers against decapentaplegic 2 0.0019 0.0004 0.0004
Brugia malayi Nuclear hormone receptor family member nhr-14 0.0068 0.0153 0.0301
Plasmodium falciparum holo-[acyl-carrier-protein] synthase, putative 0.0027 0.0027 0.0044
Plasmodium falciparum ATP-dependent DNA helicase Q1 0.0029 0.0035 0.0059
Mycobacterium ulcerans dihydrolipoamide dehydrogenase 0.0034 0.0048 0.0358
Mycobacterium tuberculosis Putative ferredoxin reductase 0.0221 0.0616 0.5019
Loa Loa (eye worm) hypothetical protein 0.0021 0.0012 0.0023
Wolbachia endosymbiont of Brugia malayi dihydrolipoamide dehydrogenase E3 component 0.0034 0.0048 0.0358
Echinococcus multilocularis ATP dependent DNA helicase Q1 0.0029 0.0035 0.0035
Brugia malayi tailless protein 0.003 0.0036 0.0071
Loa Loa (eye worm) hypothetical protein 0.0037 0.006 0.0119
Echinococcus granulosus tubulin alpha chain 0.1291 0.3847 0.607
Mycobacterium tuberculosis Possible cytochrome P450 135A1 Cyp135A1 0.0022 0.0013 0.007
Schistosoma mansoni DNA helicase recq5 0.0029 0.0035 0.0055
Onchocerca volvulus 0.0098 0.0243 0.106
Echinococcus granulosus CREB binding protein 0.02 0.055 0.0867
Onchocerca volvulus Protein ultraspiracle homolog 0.0068 0.0153 0.0659
Onchocerca volvulus Bile acid receptor homolog 0.0068 0.0153 0.0659
Echinococcus granulosus raf serine:threonine protein kinase 0.0045 0.0082 0.013
Trichomonas vaginalis PIKK family atypical protein kinase 0.0074 0.017 0.0336
Onchocerca volvulus 0.0148 0.0393 0.1729
Trichomonas vaginalis tubulin alpha-1 chain, putative 0.0775 0.2288 0.4519
Trichomonas vaginalis ABC transporter, half transporter, putative 0.0022 0.0013 0.0025
Trichomonas vaginalis tubulin gamma chain, putative 0.0966 0.2864 0.5655
Onchocerca volvulus Putative organic anion transporter 0.0086 0.0208 0.0905
Trichomonas vaginalis conserved hypothetical protein 0.0086 0.0207 0.0408
Trichomonas vaginalis conserved hypothetical protein 0.0044 0.0079 0.0157
Brugia malayi Nuclear hormone receptor family member nhr-49 0.0068 0.0153 0.0301
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.0019 0.0005 0.001
Schistosoma mansoni hypothetical protein 0.0083 0.0197 0.0311
Brugia malayi MH1 domain containing protein 0.0043 0.0076 0.0149
Loa Loa (eye worm) tubulin alpha 2 0.0869 0.2573 0.5081
Echinococcus granulosus Tubulin beta 2C chain 0.1694 0.5064 0.7989
Echinococcus granulosus multidrug resistance protein 1 0.0022 0.0013 0.002
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0021 0.0009 0.0018
Giardia lamblia Fructose-bisphosphate aldolase 0.0333 0.0952 0.1871
Trichomonas vaginalis conserved hypothetical protein 0.0422 0.1221 0.2412
Brugia malayi steroid hormone receptor 0.0068 0.0153 0.0301
Trichomonas vaginalis ABC transporter, putative 0.0022 0.0013 0.0025
Trichomonas vaginalis PIKK family atypical protein kinase 0.0031 0.0041 0.0081
Brugia malayi Nuclear hormone receptor-like 1 0.0068 0.0153 0.0301
Mycobacterium tuberculosis Probable cytochrome P450 138 Cyp138 0.0022 0.0013 0.007
Brugia malayi Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain containing protein 0.0025 0.0022 0.0042
Treponema pallidum NADH oxidase 0.0034 0.0048 0.0358
Echinococcus multilocularis tubulin delta chain 0.0422 0.1221 0.1221
Echinococcus granulosus lipoxygenase domain containing protein 0.016 0.0431 0.068
Echinococcus multilocularis protein dispatched 1 0.0098 0.0243 0.0243
Leishmania major beta tubulin 0.1694 0.5064 1
Brugia malayi hypothetical protein 0.003 0.0036 0.0071
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0068 0.0153 0.0301
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.0068 0.0153 0.0241
Trichomonas vaginalis tubulin beta chain, putative 0.1291 0.3847 0.7598
Schistosoma mansoni nuclear hormone receptor 0.003 0.0036 0.0057
Brugia malayi Cytochrome P450 family protein 0.0022 0.0013 0.0027
Echinococcus granulosus thioredoxin glutathione reductase 0.0097 0.024 0.0379
Trichomonas vaginalis adenylate cyclase, putative 0.0052 0.0104 0.0205
Treponema pallidum diphosphate--fructose-6-phosphate 1-phosphotransferase 0.003 0.0039 0.028
Schistosoma mansoni lipoxygenase 0.0641 0.1882 0.2969
Schistosoma mansoni tubulin subunit beta 0.1694 0.5064 0.7989
Brugia malayi alpha keto acid dehydrogenase complex, E3 component, lipoamide dehydrogenase 0.0025 0.0022 0.0042
Schistosoma mansoni nuclear receptor 0.003 0.0036 0.0057
Schistosoma mansoni ataxia telangiectasia mutated (atm)-related 0.0093 0.0228 0.0359
Schistosoma mansoni hypothetical protein 0.0083 0.0197 0.0311
Mycobacterium ulcerans cytochrome P450 108B4 Cyp108B4 0.0022 0.0013 0.007
Echinococcus granulosus alpha tubulin 0.1291 0.3847 0.607
Echinococcus multilocularis regulator of G protein signaling 7 0.0044 0.0079 0.0079
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0034 0.0048 0.0096
Brugia malayi PAS domain containing protein 0.02 0.055 0.1086
Trypanosoma cruzi PAS-domain containing phosphoglycerate kinase, putative 0.0052 0.0104 0.0205
Echinococcus multilocularis Niemann Pick C1 protein 0.0286 0.0812 0.0812
Giardia lamblia Ubiquitin carboxyl-terminal hydrolase 4 0.0037 0.006 0.0109
Schistosoma mansoni single-minded 0.02 0.055 0.0868
Echinococcus multilocularis Tubulin beta 2C chain 0.1694 0.5064 0.5064
Brugia malayi CHE-14 protein 0.0086 0.0207 0.0408
Brugia malayi hypothetical protein 0.003 0.0036 0.0071
Onchocerca volvulus 0.0083 0.0197 0.0857
Echinococcus granulosus dnaJ subfamily B 0.0833 0.2462 0.3884
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.0068 0.0153 0.0301
Schistosoma mansoni regulator of G protein signaling 0.0044 0.0079 0.0125
Echinococcus multilocularis Solute carrier organic anion transporter family 0.0086 0.0208 0.0208
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 8 0.0037 0.006 0.006
Loa Loa (eye worm) hypothetical protein 0.0059 0.0125 0.0247
Echinococcus multilocularis CREB binding protein 0.0033 0.0046 0.0046
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0037 0.006 0.0119
Brugia malayi Kazal-type serine protease inhibitor domain containing protein 0.0059 0.0125 0.0247
Mycobacterium ulcerans cytochrome P450 142A3 Cyp142A3 0.0022 0.0013 0.007
Brugia malayi hypothetical protein 0.0103 0.0259 0.0512
Loa Loa (eye worm) tubulin alpha-2 chain 0.1291 0.3847 0.7598
Leishmania major beta tubulin 0.1694 0.5064 1
Loa Loa (eye worm) alpha-tubulin isotype 2 0.0869 0.2573 0.5081
Trichomonas vaginalis multidrug resistance protein 1, 2, putative 0.0022 0.0013 0.0025
Loa Loa (eye worm) hypothetical protein 0.0044 0.0079 0.0157
Trichomonas vaginalis CMGC family protein kinase 0.0104 0.0262 0.0517
Trichomonas vaginalis PIKK family atypical protein kinase 0.0093 0.0228 0.045
Brugia malayi hypothetical protein 0.0044 0.0079 0.0157
Loa Loa (eye worm) hypothetical protein 0.0068 0.0153 0.0301
Brugia malayi Tubulin alpha chain 0.1291 0.3847 0.7598
Echinococcus multilocularis smad 0.0043 0.0076 0.0076
Brugia malayi nuclear receptor subfamily 1, group D, member 1, putative 0.003 0.0036 0.0071
Leishmania major mitogen activated protein kinase 4, putative;with=GeneDB:LmxM19.1440 0.0104 0.0262 0.0507
Echinococcus multilocularis tubulin alpha chain 0.1291 0.3847 0.3847
Brugia malayi nuclear receptor RXR 0.003 0.0036 0.0071
Schistosoma mansoni 6-phosphofructokinase 0.0113 0.0288 0.0454
Echinococcus granulosus tubulin beta 4A class IVa 0.1694 0.5064 0.7989
Schistosoma mansoni thyroid hormone receptor 0.0068 0.0153 0.0241
Mycobacterium ulcerans cytochrome P450 187A4 Cyp187A4 0.0022 0.0013 0.007
Echinococcus multilocularis mothers against decapentaplegic 6 0.0019 0.0004 0.0004
Leishmania major gamma-tubulin 0.0966 0.2865 0.5653
Brugia malayi Kazal-type serine protease inhibitor domain containing protein 0.0059 0.0125 0.0247
Brugia malayi isocitrate dehydrogenase 0.0032 0.0044 0.0087
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0189 0.0517 0.0816
Echinococcus multilocularis jun protein 0.0269 0.0758 0.0758
Echinococcus granulosus agrin 0.0059 0.0125 0.0197
Echinococcus granulosus 6 phosphofructokinase 0.0113 0.0288 0.0454
Onchocerca volvulus 0.0516 0.1506 0.6677
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.0068 0.0153 0.0241
Loa Loa (eye worm) hypothetical protein 0.0022 0.0013 0.0025
Echinococcus granulosus regulator of G protein signaling 3 0.0044 0.0079 0.0125
Schistosoma mansoni steroid hormone receptor ad4bp 0.0068 0.0153 0.0241
Loa Loa (eye worm) hypothetical protein 0.0044 0.0079 0.0157
Leishmania major delta tubulin, putative 0.0594 0.1741 0.3432
Echinococcus multilocularis beta adrenergic receptor kinase 0.0045 0.0082 0.0082
Plasmodium vivax 6-phosphofructokinase, putative 0.003 0.0039 0.0067
Onchocerca volvulus 0.003 0.0036 0.0141
Echinococcus multilocularis tyrosyl DNA phosphodiesterase 1 0.0067 0.0149 0.0149
Schistosoma mansoni tubulin subunit alpha 0.0422 0.1221 0.1927
Schistosoma mansoni intermediate filament proteins 0.0083 0.0197 0.0311
Echinococcus multilocularis TGF beta signal transducer SmadC 0.0043 0.0076 0.0076
Onchocerca volvulus Huntingtin homolog 0.0392 0.113 0.5007
Toxoplasma gondii CMGC kinase, MAPK family (ERK) MAPK-1 0.0104 0.0262 0.0517
Leishmania major alpha tubulin 0.1291 0.3847 0.7596
Schistosoma mansoni follistatin 0.0059 0.0125 0.0197
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0068 0.0153 0.0301
Loa Loa (eye worm) hypothetical protein 0.0775 0.2288 0.4519
Brugia malayi Tubulin alpha-2 chain 0.1291 0.3847 0.7598
Loa Loa (eye worm) intermediate filament protein 0.0083 0.0197 0.039
Mycobacterium tuberculosis Probable endonuclease IV End (endodeoxyribonuclease IV) (apurinase) 0.0078 0.0183 0.1467
Loa Loa (eye worm) nuclear hormone receptor-like 1 0.0039 0.0063 0.0125
Echinococcus granulosus mothers against decapentaplegic 5 0.0043 0.0076 0.0119
Leishmania major zeta tubulin, putative 0.0709 0.209 0.4121
Trichomonas vaginalis helicase, putative 0.0021 0.0009 0.0018
Mycobacterium tuberculosis Possible cytochrome P450 126 Cyp126 0.0022 0.0013 0.007
Brugia malayi Tubulin gamma chain 0.0966 0.2865 0.5657
Echinococcus granulosus Tubulin alpha 1 chain 0.1291 0.3847 0.607
Brugia malayi ATP-dependent DNA helicase, RecQ family protein 0.0029 0.0035 0.0069
Echinococcus granulosus tumor protein p63 0.1372 0.4092 0.6456
Loa Loa (eye worm) CXXC zinc finger family protein 0.0091 0.0222 0.0439
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0333 0.0952 0.1879
Plasmodium falciparum ataxin-2 like protein, putative 0.0103 0.0259 0.0503
Loa Loa (eye worm) hypothetical protein 0.0021 0.0009 0.0018
Trichomonas vaginalis phosphofructokinase, putative 0.0113 0.0288 0.0568
Echinococcus granulosus Aryl hydrocarbon receptor nuclear 0.0052 0.0104 0.0163
Leishmania major beta tubulin 0.1694 0.5064 1
Onchocerca volvulus 0.0086 0.0208 0.0905
Echinococcus granulosus intermediate filament protein 0.0083 0.0197 0.0311
Schistosoma mansoni axis inhibition protein axin 0.0044 0.0079 0.0125
Echinococcus granulosus cytoplasmic intermediate filament protein 0.004 0.0068 0.0107
Trypanosoma cruzi STE group serine/threonine-protein kinase, putative 0.0053 0.0106 0.021
Trichomonas vaginalis PIKK family atypical protein kinase 0.005 0.0099 0.0195
Loa Loa (eye worm) cytochrome P450 family protein 0.0068 0.0151 0.0298
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0333 0.0952 0.1879
Trichomonas vaginalis phosphofructokinase, putative 0.003 0.0039 0.0077
Schistosoma mansoni lipoxygenase 0.0352 0.1011 0.1594
Echinococcus granulosus neuropeptide receptor A26 0.0946 0.2804 0.4423
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.0068 0.0153 0.0241
Echinococcus multilocularis multidrug resistance protein 1 0.0022 0.0013 0.0013
Schistosoma mansoni ap endonuclease 0.0019 0.0005 0.0008
Trichomonas vaginalis tubulin alpha-1 chain, putative 0.0869 0.2573 0.5081
Loa Loa (eye worm) hypothetical protein 0.003 0.0036 0.0071
Echinococcus granulosus arachidonate 5 lipoxygenase 0.0641 0.1882 0.2969
Echinococcus granulosus 5'partial|ATP binding cassette sub family B 0.0021 0.0012 0.0019
Schistosoma mansoni 6-phosphofructokinase 0.0113 0.0288 0.0454
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription factor 0.0269 0.0758 0.0758
Onchocerca volvulus 0.0086 0.0208 0.0905
Trichomonas vaginalis PIKK family atypical protein kinase 0.0056 0.0115 0.0226
Toxoplasma gondii exonuclease III APE 0.0019 0.0005 0.001
Entamoeba histolytica hypothetical protein 0.0189 0.0517 0.1022
Trichomonas vaginalis PIKK family atypical protein kinase 0.006 0.0129 0.0255
Trichomonas vaginalis conserved hypothetical protein 0.0021 0.0009 0.0018
Echinococcus multilocularis CREB binding protein 0.0033 0.0046 0.0046
Brugia malayi prostaglandin transporter 0.0086 0.0208 0.0411
Echinococcus multilocularis Tubulin beta 2C chain 0.1694 0.5064 0.5064
Toxoplasma gondii pyruvate dehydrogenase complex subunit PDH-E3II 0.0034 0.0048 0.0096
Loa Loa (eye worm) hypothetical protein 0.0286 0.081 0.1599
Loa Loa (eye worm) 6-phosphofructokinase 0.0113 0.0288 0.0568
Mycobacterium ulcerans cytochrome P450 126A3 Cyp126A3 0.0022 0.0013 0.007
Echinococcus granulosus tubulin alpha 3 chain 0.1291 0.3847 0.607
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.0068 0.0153 0.0659
Echinococcus granulosus dihydrolipoamide dehydrogenase 0.0034 0.0048 0.0076
Schistosoma mansoni organic anion transporter 0.0086 0.0208 0.0328
Schistosoma mansoni hypothetical protein 0.089 0.2634 0.4156
Schistosoma mansoni regulator of G protein signaling 0.0045 0.0083 0.013
Mycobacterium tuberculosis Probable cytochrome P450 128 Cyp128 0.0022 0.0013 0.007
Echinococcus granulosus microtubule associated protein 2 0.2116 0.6339 1
Treponema pallidum 4'-phosphopantetheinyl transferase 0.0027 0.0027 0.0184
Echinococcus granulosus organic anion transporting polypeptide 30B 0.0086 0.0208 0.0328
Trichomonas vaginalis PIKK family atypical protein kinase 0.0069 0.0156 0.0308
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0104 0.0262 0.0517
Schistosoma mansoni jumonji domain containing protein 0.006 0.0127 0.02
Trichomonas vaginalis conserved hypothetical protein 0.0037 0.006 0.0119
Schistosoma mansoni rab6-interacting 0.016 0.0431 0.068
Trichomonas vaginalis phosphofructokinase, putative 0.003 0.0039 0.0077
Echinococcus multilocularis ATP binding cassette subfamily B (MDR:TAP) 0.0022 0.0013 0.0013
Echinococcus multilocularis tumor protein p63 0.1372 0.4092 0.4092
Schistosoma mansoni regulator of G protein signaling 17 19 20 (rgs17 19 20) 0.0044 0.0079 0.0125
Leishmania major p-glycoprotein 0.0022 0.0013 0.0015
Onchocerca volvulus 0.0083 0.0197 0.0857
Mycobacterium ulcerans cytochrome P450 140A5 Cyp140A5 0.0022 0.0013 0.007
Treponema pallidum fructose-bisphosphate aldolase 0.0333 0.0952 0.7782
Onchocerca volvulus 0.0052 0.0104 0.0441
Toxoplasma gondii Kazal-type serine protease inhibitor domain-containing protein 0.0059 0.0125 0.0247
Loa Loa (eye worm) hypothetical protein 0.003 0.0036 0.0071
Echinococcus granulosus lysine specific demethylase 5A 0.0065 0.0143 0.0225
Entamoeba histolytica tubulin alpha chain, putative 0.1291 0.3847 0.7598
Schistosoma mansoni hypothetical protein 0.0083 0.0197 0.0311
Mycobacterium tuberculosis Probable 6-phosphofructokinase PfkA (phosphohexokinase) (phosphofructokinase) 0.0113 0.0288 0.2324
Loa Loa (eye worm) CYP4Cod1 0.0068 0.0151 0.0298
Schistosoma mansoni dihydrolipoamide dehydrogenase 0.0034 0.0048 0.0076
Brugia malayi Nuclear hormone receptor family member nhr-1 0.0068 0.0153 0.0301
Leishmania major beta tubulin 0.1694 0.5064 1
Trichomonas vaginalis conserved hypothetical protein 0.0052 0.0104 0.0205
Leishmania major beta tubulin 0.1694 0.5064 1
Echinococcus granulosus nuclear receptor subfamily 4 group A 0.003 0.0036 0.0057
Entamoeba histolytica hypothetical protein 0.0044 0.0079 0.0157
Echinococcus multilocularis L aminoadipate semialdehyde 0.0095 0.0233 0.0233
Plasmodium vivax SET domain protein, putative 0.0098 0.0243 0.047
Toxoplasma gondii 4'-phosphopantetheinyl transferase domain-containing protein 0.0027 0.0027 0.0054
Trichomonas vaginalis PIKK family atypical protein kinase 0.0093 0.0228 0.045
Loa Loa (eye worm) follicle stimulating hormone receptor 0.0246 0.0691 0.1364
Echinococcus multilocularis ubiquitin specific protease 41 0.0037 0.006 0.006
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0098 0.0243 0.0383
Loa Loa (eye worm) hypothetical protein 0.0044 0.0079 0.0157
Schistosoma mansoni tyrosyl-DNA phosphodiesterase 0.0067 0.0149 0.0235
Loa Loa (eye worm) tubulin beta-4 chain 0.1694 0.5064 1
Toxoplasma gondii Kazal-type serine protease inhibitor domain-containing protein 0.0059 0.0125 0.0247
Trypanosoma cruzi PAB1-binding protein , putative 0.0103 0.0259 0.0512
Schistosoma mansoni regulator of G protein signaling 0.0044 0.0079 0.0125
Brugia malayi sodium-independent organic anion transporter family protein 0.0086 0.0208 0.0411
Brugia malayi bZIP transcription factor family protein 0.0269 0.0758 0.1497
Loa Loa (eye worm) hypothetical protein 0.0392 0.113 0.2232
Trichomonas vaginalis taga, putative 0.0022 0.0013 0.0025
Mycobacterium tuberculosis Probable isocitrate dehydrogenase [NADP] Icd1 (oxalosuccinate decarboxylase) (IDH) (NADP+-specific ICDH) (IDP) 0.0032 0.0044 0.0322
Loa Loa (eye worm) hypothetical protein 0.02 0.0552 0.1091
Entamoeba histolytica P-glycoprotein-2 0.0022 0.0013 0.0025
Schistosoma mansoni survival motor neuron protein 0.0058 0.0123 0.0194
Loa Loa (eye worm) hypothetical protein 0.0039 0.0063 0.0125
Brugia malayi beta-tubulin, identical 0.1694 0.5064 1
Echinococcus granulosus tubulin alpha chain 0.1291 0.3847 0.607
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.0068 0.0153 0.0301
Loa Loa (eye worm) hypothetical protein 0.0081 0.0193 0.0381
Trichomonas vaginalis multidrug resistance protein 1, 2, putative 0.0022 0.0013 0.0025
Echinococcus granulosus tubulin alpha chain 0.1291 0.3847 0.607
Plasmodium vivax tubulin beta chain, putative 0.1694 0.5064 1
Schistosoma mansoni tubulin subunit alpha 0.1291 0.3847 0.607
Schistosoma mansoni cytochrome P450 0.0022 0.0013 0.0021
Trypanosoma cruzi tubulin delta chain 0.0594 0.1741 0.3438
Brugia malayi hypothetical protein 0.0392 0.113 0.2232
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0098 0.0243 0.0383
Leishmania major hypothetical protein, conserved 0.0103 0.0259 0.0503
Schistosoma mansoni tubulin subunit epsilon 0.0966 0.2864 0.4518
Echinococcus multilocularis tubulin subunit beta 0.1694 0.5064 0.5064
Trichomonas vaginalis multidrug resistance protein 1, 2, putative 0.0022 0.0013 0.0025
Schistosoma mansoni loxhd1 0.016 0.0431 0.068
Entamoeba histolytica tubulin alpha-1 chain 0.1291 0.3847 0.7598
Schistosoma mansoni ecdysone-induced protein 78c (dr-78) 0.0039 0.0063 0.01
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.0029 0.0035 0.0069
Loa Loa (eye worm) pax transcription factor protein 2 0.0244 0.0684 0.1351
Trypanosoma cruzi target of rapamycin kinase 3 0.0074 0.017 0.0337
Trichomonas vaginalis conserved hypothetical protein 0.0021 0.0009 0.0018
Trichomonas vaginalis PIKK family atypical protein kinase 0.0031 0.0041 0.0081
Trypanosoma brucei ATP-dependent 6-phosphofructokinase, glycosomal 0.0113 0.0288 0.0568
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0671 0.1974 0.3898
Onchocerca volvulus 0.0059 0.0125 0.0536
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0034 0.0048 0.0096
Echinococcus granulosus Nuclear hormone receptor HR96 0.003 0.0036 0.0057
Loa Loa (eye worm) hypothetical protein 0.067 0.197 0.3891
Brugia malayi MH1 domain containing protein 0.0024 0.0018 0.0036
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0039 0.0063 0.01
Trypanosoma cruzi PAS-domain containing phosphoglycerate kinase, putative 0.0052 0.0104 0.0205
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0104 0.0262 0.0517
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.003 0.0036 0.0036
Brugia malayi phosphofructokinase 0.0113 0.0288 0.0568
Echinococcus multilocularis Transcription factor, JmjC domain containing protein 0.006 0.0127 0.0127
Echinococcus granulosus tubulin alpha 0.0938 0.2781 0.4387
Trichomonas vaginalis PIKK family atypical protein kinase 0.0074 0.017 0.0336
Schistosoma mansoni tubulin subunit delta 0.0422 0.1221 0.1927
Trichomonas vaginalis abcb9, putative 0.0022 0.0013 0.0025
Loa Loa (eye worm) hypothetical protein 0.0059 0.0125 0.0247
Schistosoma mansoni phosphatidylinositol 3-and 4-kinase 0.0031 0.0041 0.0065
Schistosoma mansoni ap endonuclease 0.0019 0.0005 0.0008
Brugia malayi ecdysteroid receptor 0.0068 0.0153 0.0301
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0098 0.0243 0.0383
Schistosoma mansoni ubiquitin-specific peptidase 8 (C19 family) 0.0037 0.006 0.0095
Brugia malayi Nuclear hormone receptor E75 0.003 0.0036 0.0071
Trichomonas vaginalis CMGC family protein kinase 0.0104 0.0262 0.0517
Echinococcus multilocularis tubulin alpha 1C chain 0.1291 0.3847 0.3847
Plasmodium vivax thioredoxin reductase, putative 0.0097 0.024 0.0465
Wolbachia endosymbiont of Brugia malayi cell division protein FtsZ 0.0422 0.1221 1
Schistosoma mansoni regulator of G protein signaling 0.0044 0.0079 0.0125
Entamoeba histolytica P-glycoprotein-2 0.0022 0.0013 0.0025
Brugia malayi jmjC domain containing protein 0.006 0.0127 0.0251
Brugia malayi glutathione reductase 0.0097 0.024 0.0474
Trypanosoma cruzi tubulin gamma chain 0.0966 0.2865 0.5657
Echinococcus granulosus Jumonji AT rich interactive domain 1B 0.0021 0.0011 0.0017
Mycobacterium tuberculosis Conserved hypothetical protein 0.0021 0.0009 0.0034
Brugia malayi secreted modular calcium-binding protein 1 0.0059 0.0125 0.0247
Echinococcus multilocularis mothers against decapentaplegic 5 0.0043 0.0076 0.0076
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.0068 0.0153 0.0241
Loa Loa (eye worm) hypothetical protein 0.0201 0.0554 0.1093
Brugia malayi Tubulin alpha-2 chain 0.1291 0.3847 0.7598
Trichomonas vaginalis PIKK family atypical protein kinase 0.0055 0.0113 0.0223
Giardia lamblia Epsilon tubulin 0.0449 0.1304 0.2569
Echinococcus granulosus L aminoadipate semialdehyde 0.0095 0.0233 0.0367
Mycobacterium tuberculosis Probable cytochrome P450 monooxygenase 142 Cyp142 0.0022 0.0013 0.007
Schistosoma mansoni hypothetical protein 0.016 0.0431 0.068
Echinococcus granulosus ATP binding cassette subfamily B MDR:TAP 0.0022 0.0013 0.002
Schistosoma mansoni tubulin subunit beta 0.1694 0.5064 0.7989
Brugia malayi nuclear hormone receptor 0.0068 0.0153 0.0301
Schistosoma mansoni cpg binding protein 0.0091 0.0222 0.0351
Echinococcus granulosus mothers against decapentaplegic 6 0.0019 0.0004 0.0007
Toxoplasma gondii target of rapamycin (TOR), putative 0.0069 0.0156 0.0308
Leishmania major phosphatidylinositol 3-related kinase, putative 0.0031 0.0041 0.0071
Echinococcus multilocularis ATP binding cassette subfamily B (MDR:TAP) 0.0022 0.0013 0.0013
Brugia malayi Nuclear hormone receptor family member nhr-40 0.0068 0.0153 0.0301
Toxoplasma gondii 4'-phosphopantetheinyl transferase superfamily protein 0.0027 0.0027 0.0054
Loa Loa (eye worm) nuclear factor I 0.0024 0.0018 0.0036
Echinococcus multilocularis CREB binding protein 0.0137 0.036 0.036
Toxoplasma gondii beta-1 tubulin, putative 0.1694 0.5064 1
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.0333 0.0952 0.1879
Mycobacterium ulcerans aldehyde dehydrogenase 0.0062 0.0134 0.1063
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0098 0.0243 0.0243
Trypanosoma cruzi tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0067 0.0149 0.0294
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase domain containing protein 0.0037 0.006 0.0119
Giardia lamblia Beta tubulin 0.1694 0.5064 1
Brugia malayi Kazal-type serine protease inhibitor domain containing protein 0.0059 0.0125 0.0247
Mycobacterium tuberculosis Probable fructose-bisphosphate aldolase Fba 0.0162 0.0438 0.3558
Toxoplasma gondii endonuclease IV APN 0.0078 0.0183 0.0362
Schistosoma mansoni smad1 5 8 and 0.0043 0.0076 0.0119
Echinococcus multilocularis regulator of G protein signaling 3 0.0044 0.0079 0.0079
Schistosoma mansoni jumonji/arid domain-containing protein 0.0065 0.0143 0.0225
Schistosoma mansoni organic anion transporter 0.0086 0.0208 0.0328
Entamoeba histolytica hypothetical protein 0.0189 0.0517 0.1022
Echinococcus multilocularis ecdysone induced protein 78C 0.0068 0.0153 0.0153
Trichomonas vaginalis tubulin epsilon chain, putative 0.1694 0.5064 1
Loa Loa (eye worm) hypothetical protein 0.003 0.0036 0.0071
Loa Loa (eye worm) hypothetical protein 0.0105 0.0265 0.0524
Trichomonas vaginalis phosphofructokinase, putative 0.003 0.0039 0.0077
Trypanosoma cruzi tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0067 0.0149 0.0294
Leishmania major beta tubulin 0.1694 0.5064 1
Echinococcus granulosus follistatin 0.0059 0.0125 0.0197
Loa Loa (eye worm) hypothetical protein 0.003 0.0036 0.0071
Trichomonas vaginalis tubulin alpha-1 chain, putative 0.0516 0.1506 0.2974
Brugia malayi TAZ zinc finger family protein 0.02 0.055 0.1086
Brugia malayi Isocitrate dehydrogenase 0.0032 0.0044 0.0087
Loa Loa (eye worm) hypothetical protein 0.0095 0.0233 0.046
Plasmodium vivax glutathione reductase, putative 0.0097 0.024 0.0465
Leishmania major beta tubulin 0.1694 0.5064 1
Echinococcus granulosus cpg binding protein 0.0096 0.0238 0.0375
Echinococcus multilocularis transfer RNA-Lys 0.0148 0.0393 0.0393
Loa Loa (eye worm) hypothetical protein 0.0086 0.0208 0.0411
Echinococcus multilocularis musashi 0.0083 0.0197 0.0197
Trypanosoma brucei epsilon tubulin 0.0966 0.2864 0.5655
Brugia malayi sodium-independent organic anion transporter family protein 0.0086 0.0208 0.0411
Echinococcus multilocularis regulator of G protein signaling 7 0.0044 0.0079 0.0079
Mycobacterium tuberculosis Probable cytochrome P450 125 Cyp125 0.0022 0.0013 0.007
Loa Loa (eye worm) alpha-tubulin 0.1291 0.3847 0.7598
Brugia malayi Raf kinase 0.0045 0.0082 0.0162
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.0068 0.0153 0.0153
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.0068 0.0153 0.0301
Brugia malayi photoreceptor-specific nuclear receptor 0.0068 0.0153 0.0301
Loa Loa (eye worm) hypothetical protein 0.0086 0.0207 0.0408
Schistosoma mansoni z-protein (S1r protein) 0.0044 0.0079 0.0125
Mycobacterium tuberculosis Probable membrane NADH dehydrogenase NdhA 0.0221 0.0616 0.5019
Trichomonas vaginalis PIKK family atypical protein kinase 0.0069 0.0156 0.0308
Brugia malayi F/Y-rich N-terminus family protein 0.0031 0.0042 0.0082
Echinococcus multilocularis peroxisome assembly protein 26 0.1291 0.3847 0.3847
Echinococcus granulosus aldehyde dehydrogenase mitochondrial 0.0062 0.0134 0.0212
Schistosoma mansoni jumonji/arid domain-containing protein 0.0065 0.0143 0.0225
Loa Loa (eye worm) hypothetical protein 0.0078 0.0183 0.0362
Mycobacterium ulcerans endonuclease IV 0.0078 0.0183 0.1467
Loa Loa (eye worm) AGC/GRK/BARK protein kinase 0.0045 0.0082 0.0162
Echinococcus granulosus Tubulin alpha 1 chain 0.1291 0.3847 0.607
Schistosoma mansoni regulator of G protein signaling 0.0044 0.0079 0.0125
Loa Loa (eye worm) hypothetical protein 0.003 0.0036 0.0071
Echinococcus granulosus Tubulin beta 2C chain 0.1694 0.5064 0.7989
Loa Loa (eye worm) multidrug resistance protein 3 0.0022 0.0013 0.0025
Schistosoma mansoni alpha tubulin 0.1291 0.3847 0.607
Brugia malayi Nuclear hormone receptor-like 1 0.0039 0.0063 0.0125
Schistosoma mansoni CREB-binding protein 1 (SmCBP1) 0.02 0.055 0.0867
Trichomonas vaginalis glutathione reductase, putative 0.0034 0.0048 0.0096
Trypanosoma brucei phosphatidylinositol 3-kinase tor, putative 0.0044 0.008 0.0157
Mycobacterium leprae DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE 0.0246 0.069 0.5618
Brugia malayi tubulin alpha chain - mouse 0.1291 0.3847 0.7598
Schistosoma mansoni aldehyde dehydrogenase 0.0062 0.0134 0.0212
Plasmodium falciparum ATP-dependent 6-phosphofructokinase 0.003 0.0039 0.0067
Trichomonas vaginalis tubulin epsilon chain, putative 0.1291 0.3847 0.7598
Brugia malayi multidrug resistance protein 3 0.0022 0.0013 0.0025
Brugia malayi Nuclear hormone receptor family member nhr-3 0.0068 0.0153 0.0301
Mycobacterium ulcerans epimerase 0.0021 0.0009 0.0034
Mycobacterium tuberculosis Probable NADH dehydrogenase Ndh 0.0221 0.0616 0.5019
Toxoplasma gondii histone lysine methyltransferase SET1 0.018 0.049 0.0967
Echinococcus multilocularis lipoxygenase domain containing protein 0.016 0.0431 0.0431
Brugia malayi hypoxia-induced factor 1 0.0618 0.1813 0.3581
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0068 0.0153 0.0241
Echinococcus multilocularis Regulator of G protein signaling 20 0.0044 0.0079 0.0079
Wolbachia endosymbiont of Brugia malayi dihydrolipoamide dehydrogenase E3 component 0.0034 0.0048 0.0358
Trichomonas vaginalis tubulin beta chain, putative 0.1694 0.5064 1
Mycobacterium ulcerans 4'-phosphopantetheinyl transferase 0.0027 0.0027 0.0184
Schistosoma mansoni smad1 5 8 and 0.0043 0.0076 0.0119
Brugia malayi exodeoxyribonuclease III family protein 0.0019 0.0005 0.001
Echinococcus granulosus ATP dependent DNA helicase Q5 0.0029 0.0035 0.0055
Schistosoma mansoni TGF-beta signal transducer Smad2 0.0043 0.0076 0.0119
Toxoplasma gondii ATP-binding cassette transporter ABC.B1 0.0022 0.0013 0.0025
Loa Loa (eye worm) hypothetical protein 0.003 0.0036 0.0071
Echinococcus granulosus peroxisome assembly protein 26 0.1291 0.3847 0.607
Echinococcus multilocularis tubulin alpha 0.0938 0.2781 0.2781
Echinococcus multilocularis tubulin alpha chain 0.1291 0.3847 0.3847
Mycobacterium tuberculosis Probable cytochrome P450 144 Cyp144 0.0022 0.0013 0.007
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0092 0.0226 0.0357
Loa Loa (eye worm) tyrosyl-DNA phosphodiesterase 0.0067 0.0149 0.0294
Echinococcus multilocularis aldehyde dehydrogenase, mitochondrial 0.0062 0.0134 0.0134
Schistosoma mansoni multidrug resistance protein 0.0022 0.0013 0.002
Echinococcus granulosus survival motor neuron protein 1 0.0286 0.081 0.1277
Mycobacterium ulcerans cytochrome P450 189A7 Cyp189A7 0.0022 0.0013 0.007
Trichomonas vaginalis ap endonuclease, putative 0.0019 0.0005 0.001
Loa Loa (eye worm) hypothetical protein 0.0059 0.0125 0.0247
Mycobacterium leprae PROBABLE ENDONUCLEASE IV END (ENDODEOXYRIBONUCLEASE IV) (APURINASE) 0.0078 0.0183 0.1438
Onchocerca volvulus Huntingtin homolog 0.0392 0.113 0.5007
Onchocerca volvulus 0.0086 0.0208 0.0905
Mycobacterium leprae Conserved hypothetical protein 0.0022 0.0013 0.0036
Loa Loa (eye worm) nuclear hormone receptor 0.003 0.0036 0.0071
Echinococcus granulosus expressed conserved protein 0.0188 0.0516 0.0813
Schistosoma mansoni lamin 0.0083 0.0197 0.0311
Giardia lamblia Beta tubulin 0.1694 0.5064 1
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0032 0.0043 0.0067
Echinococcus granulosus nuclear receptor 2DBD gamma 0.003 0.0036 0.0057
Toxoplasma gondii alpha-tubulin I, putative 0.1291 0.3847 0.7598
Echinococcus multilocularis neuropeptide receptor A26 0.0946 0.2804 0.2804
Brugia malayi Steroid receptor seven-up type 2 0.0068 0.0153 0.0301
Trichomonas vaginalis ABC transporter, putative 0.0022 0.0013 0.0025
Echinococcus multilocularis nuclear receptor subfamily 1 group D 0.0039 0.0063 0.0063
Echinococcus multilocularis neuropeptide s receptor 0.0946 0.2804 0.2804
Trichomonas vaginalis PIKK family atypical protein kinase 0.0069 0.0156 0.0308
Schistosoma mansoni regulator of G protein signaling 3 rgs3 0.0044 0.0079 0.0125
Loa Loa (eye worm) hypothetical protein 0.003 0.0036 0.0071
Toxoplasma gondii beta-tubulin, putative 0.1694 0.5064 1
Plasmodium falciparum glutathione reductase 0.0097 0.024 0.0465
Trypanosoma brucei tubulin gamma chain 0.0966 0.2865 0.5657
Giardia lamblia Delta tubulin 0.0422 0.1221 0.2405
Trichomonas vaginalis tubulin, putative 0.045 0.1306 0.2578
Mycobacterium leprae Probable fructose bisphosphate aldolase Fba 0.0162 0.0438 0.3535
Trichomonas vaginalis PIKK family atypical protein kinase 0.0069 0.0156 0.0308
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.0083 0.0197 0.039
Trichomonas vaginalis conserved hypothetical protein 0.0052 0.0104 0.0205
Echinococcus multilocularis Polycystic kidney disease protein 0.016 0.0431 0.0431
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0068 0.0153 0.0241
Schistosoma mansoni serine/threonine protein kinase 0.0045 0.0082 0.013
Mycobacterium leprae PROBABLE NADH DEHYDROGENASE NDH 0.0221 0.0616 0.5002
Trichomonas vaginalis lipid A export ATP-binding/permease protein msba, putative 0.0022 0.0013 0.0025
Loa Loa (eye worm) hypothetical protein 0.0086 0.0208 0.0411
Loa Loa (eye worm) AGC/GRK/GRK protein kinase 0.0045 0.0082 0.0162
Loa Loa (eye worm) glutathione reductase 0.0097 0.024 0.0474
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0034 0.0048 0.0096
Mycobacterium tuberculosis Probable cytochrome P450 140 Cyp140 0.0022 0.0013 0.007
Trichomonas vaginalis tubulin, putative 0.1694 0.5064 1
Trypanosoma cruzi mitogen activated protein kinase 4, putative 0.0104 0.0262 0.0517
Echinococcus multilocularis ATP binding cassette subfamily B (MDR:TAP) 0.0022 0.0013 0.0013
Trypanosoma cruzi mitogen activated protein kinase 2, putative 0.0104 0.0262 0.0517
Brugia malayi hypothetical protein 0.0039 0.0063 0.0125
Echinococcus multilocularis axis inhibition protein axin 0.0044 0.0079 0.0079
Echinococcus multilocularis thyroid hormone receptor alpha 0.0068 0.0153 0.0153
Trichomonas vaginalis conserved hypothetical protein 0.0422 0.1221 0.2412
Echinococcus granulosus nuclear receptor nhr 48 0.003 0.0036 0.0057
Loa Loa (eye worm) hypothetical protein 0.0068 0.0153 0.0301
Plasmodium falciparum dihydrolipoyl dehydrogenase, apicoplast 0.0034 0.0048 0.0086
Trypanosoma brucei isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0032 0.0044 0.0087
Trypanosoma cruzi alpha tubulin, putative 0.1291 0.3847 0.7598
Leishmania major ATP-dependent DEAD/H DNA helicase recQ, putative 0.0032 0.0043 0.0075
Brugia malayi Doublecortin family protein 0.016 0.0431 0.0851
Plasmodium vivax holo-[acyl-carrier-protein] synthase, putative 0.0027 0.0027 0.0044
Trichomonas vaginalis tubulin alpha chain, putative 0.0516 0.1506 0.2974
Echinococcus multilocularis arachidonate 5 lipoxygenase 0.0641 0.1882 0.1882
Plasmodium vivax 6-phosphofructokinase, putative 0.003 0.0039 0.0067
Trichomonas vaginalis ap endonuclease, putative 0.0019 0.0005 0.001
Leishmania major protein kinase, putative 0.0053 0.0106 0.0201
Trichomonas vaginalis PIKK family atypical protein kinase 0.005 0.0099 0.0195
Loa Loa (eye worm) tubulin alpha chain 0.1291 0.3847 0.7598
Leishmania major alpha tubulin 0.1291 0.3847 0.7596
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0197 0.0542 0.0854
Echinococcus multilocularis tubulin alpha 3 chain 0.1291 0.3847 0.3847
Schistosoma mansoni cellular tumor antigen P53 0.0201 0.0554 0.0873
Onchocerca volvulus 0.0091 0.0222 0.0968
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0021 0.0009 0.0018
Trichomonas vaginalis soluble guanylate cyclase gcy, putative 0.0052 0.0104 0.0205
Echinococcus multilocularis tubulin alpha chain 0.1291 0.3847 0.3847
Trichomonas vaginalis tubulin beta-1 chain, putative 0.0422 0.1221 0.2412
Brugia malayi Tubulin alpha chain 0.0422 0.1221 0.2412
Loa Loa (eye worm) tubulin alpha-3 chain 0.0775 0.2288 0.4519
Echinococcus multilocularis RUN 0.016 0.0431 0.0431
Leishmania major beta tubulin 0.1694 0.5064 1
Echinococcus granulosus FKBP12 rapamycin complex associated protein 0.0093 0.0228 0.0359
Schistosoma mansoni tubulin subunit beta 0.1694 0.5064 0.7989
Loa Loa (eye worm) hypothetical protein 0.003 0.0036 0.0071
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.0068 0.0153 0.0301
Schistosoma mansoni hypothetical protein 0.0218 0.0606 0.0956
Loa Loa (eye worm) hypothetical protein 0.0044 0.0079 0.0157
Mycobacterium ulcerans cytochrome P450 188A3 Cyp188A3 0.0022 0.0013 0.007
Brugia malayi Pre-SET motif family protein 0.0098 0.0243 0.0479
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0333 0.0952 0.1879
Leishmania major beta tubulin 0.1694 0.5064 1
Toxoplasma gondii cytochrome p450 superfamily protein 0.0022 0.0013 0.0027
Trichomonas vaginalis 6-phosphofructokinase, putative 0.003 0.0039 0.0077
Loa Loa (eye worm) steroid hormone receptor 0.0068 0.0153 0.0301
Plasmodium falciparum isocitrate dehydrogenase [NADP], mitochondrial 0.0032 0.0044 0.0077
Brugia malayi nuclear hormone receptor 0.003 0.0036 0.0071
Leishmania major ATP-binding cassette protein subfamily B, member 2, putative 0.0022 0.0013 0.0015
Mycobacterium ulcerans cytochrome P450 123A3 Cyp123A3 0.0022 0.0013 0.007
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.003 0.0036 0.0141
Trichomonas vaginalis PIKK family atypical protein kinase 0.0056 0.0115 0.0226
Onchocerca volvulus 0.003 0.0036 0.0141
Leishmania major phosphatidylinositol 3-kinase, putative 0.0031 0.0041 0.0071
Trichomonas vaginalis ATP-binding cassette transporter, putative 0.0022 0.0013 0.0025
Trichomonas vaginalis lipid A export ATP-binding/permease protein msba, putative 0.0022 0.0013 0.0025
Echinococcus multilocularis FTZ F1 alpha 0.0068 0.0153 0.0153
Brugia malayi Intermediate filament tail domain containing protein 0.0083 0.0197 0.039
Mycobacterium tuberculosis Probable cytochrome P450 137 Cyp137 0.0022 0.0013 0.007
Trichomonas vaginalis tubulin beta chain, putative 0.1291 0.3847 0.7598
Mycobacterium tuberculosis Probable transmembrane multidrug efflux pump 0.0022 0.0013 0.0063
Loa Loa (eye worm) PXA domain-containing protein 0.0044 0.0079 0.0157
Schistosoma mansoni serine/threonine protein kinase 0.0045 0.0082 0.013
Schistosoma mansoni nuclear hormone receptor 0.0068 0.0153 0.0241
Toxoplasma gondii tubulin/FtsZ family, GTPase domain-containing protein 0.0594 0.1741 0.3438
Trichomonas vaginalis conserved hypothetical protein 0.0052 0.0104 0.0205
Echinococcus multilocularis ATP binding cassette subfamily B (MDR:TAP) 0.0022 0.0013 0.0013
Toxoplasma gondii beta tubulin 0.1694 0.5064 1
Entamoeba histolytica P-glycoprotein-1 0.0022 0.0013 0.0025
Trichomonas vaginalis CMGC family protein kinase 0.0104 0.0262 0.0517
Toxoplasma gondii thioredoxin reductase 0.0097 0.024 0.0474
Schistosoma mansoni serine/threonine protein kinase 0.0045 0.0082 0.013
Onchocerca volvulus 0.0211 0.0584 0.2577
Echinococcus granulosus tubulin alpha chain 0.1291 0.3847 0.607
Echinococcus multilocularis agrin 0.0059 0.0125 0.0125
Loa Loa (eye worm) tubulin gamma chain 0.0966 0.2865 0.5657
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0333 0.0952 0.1879
Echinococcus granulosus ATP binding cassette subfamily B MDR:TAP 0.0022 0.0013 0.002
Trichomonas vaginalis tubulin alpha chain, putative 0.0516 0.1506 0.2974
Schistosoma mansoni alpha tubulin 0.1291 0.3847 0.607
Loa Loa (eye worm) kazal-type serine protease inhibitor domain-containing protein 0.0059 0.0125 0.0247
Wolbachia endosymbiont of Brugia malayi 4'-phosphopantetheinyl transferase 0.0027 0.0027 0.0184
Plasmodium vivax tubulin gamma chain, putative 0.0966 0.2865 0.5653
Trichomonas vaginalis DNA helicase recq1, putative 0.0042 0.0073 0.0145
Brugia malayi Pre-SET motif family protein 0.0671 0.1974 0.3898
Trichomonas vaginalis ATP-binding cassette transporter, putative 0.0022 0.0013 0.0025
Treponema pallidum cell division protein FtsZ 0.0422 0.1221 1
Brugia malayi Tubulin beta chain 0.0422 0.1221 0.2412
Mycobacterium ulcerans putative regulatory protein 0.0148 0.0393 0.3192
Mycobacterium ulcerans phosphopantetheinyl transferase, PptII 0.0027 0.0027 0.0184
Schistosoma mansoni rab6-interacting 0.016 0.0431 0.068
Schistosoma mansoni alpha tubulin 0.1291 0.3847 0.607
Trypanosoma brucei target of rapamycin kinase 3, putative 0.0074 0.017 0.0337
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 8 0.0037 0.006 0.0095
Trichomonas vaginalis regulator of G protein signaling 5, rgs5, putative 0.0044 0.0079 0.0157
Trichomonas vaginalis tubulin epsilon chain, putative 0.0422 0.1221 0.2412
Plasmodium falciparum alpha tubulin 1 0.1291 0.3847 0.7596
Trypanosoma brucei alpha tubulin 0.1291 0.3847 0.7598
Trypanosoma brucei ubiquitin carboxyl-terminal hydrolase, putative 0.0037 0.006 0.0119
Loa Loa (eye worm) cytochrome P450 0.0022 0.0013 0.0027
Brugia malayi cytoplasmic intermediate filament protein 0.0044 0.0081 0.016
Onchocerca volvulus Putative organic anion transporter 0.0086 0.0208 0.0905
Trichomonas vaginalis conserved hypothetical protein 0.0021 0.0009 0.0018
Echinococcus multilocularis regulator of G protein signaling 3 0.0044 0.0079 0.0079
Brugia malayi Nuclear hormone receptor family member nhr-41 0.0068 0.0153 0.0301
Brugia malayi 6-phosphofructokinase 0.0113 0.0288 0.057
Leishmania major alpha tubulin 0.1291 0.3847 0.7596
Trichomonas vaginalis guanylate cyclase, putative 0.0052 0.0104 0.0205
Schistosoma mansoni aminoadipate-semialdehyde dehydrogenase 0.0095 0.0233 0.0367
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0034 0.0048 0.0086
Schistosoma mansoni niemann-pick C1 (NPC1) 0.0204 0.0562 0.0886
Echinococcus multilocularis microtubule associated protein 2 0.2116 0.6339 0.6339
Trichomonas vaginalis PIKK family atypical protein kinase 0.0031 0.0041 0.0081
Loa Loa (eye worm) hypothetical protein 0.0086 0.0208 0.0411
Chlamydia trachomatis dihydrolipoyl dehydrogenase 0.0034 0.0048 0.2102
Trypanosoma cruzi ATP-dependent 6-phosphofructokinase, glycosomal 0.0113 0.0288 0.0568
Trichomonas vaginalis adenylate and guanylate cyclases, putative 0.0052 0.0104 0.0205
Trypanosoma cruzi STE/STE11 serine/threonine-protein kinase, putative 0.0053 0.0106 0.021
Trichomonas vaginalis multidrug resistance protein 1, 2, putative 0.0022 0.0013 0.0025
Plasmodium vivax ADP-dependent DNA helicase RecQ, putative 0.0025 0.0022 0.0034
Trypanosoma cruzi Phosphatidylinositol 3-kinase tor2 0.0093 0.0228 0.045
Leishmania major beta tubulin 0.1694 0.5064 1
Mycobacterium ulcerans cytochrome P450 124A1, Cyp124A1 0.0022 0.0013 0.007
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.0068 0.0153 0.0153
Plasmodium vivax ataxin-2 like protein, putative 0.0103 0.0259 0.0503
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.0068 0.0153 0.0241
Toxoplasma gondii Kazal-type serine protease inhibitor domain-containing protein 0.0059 0.0125 0.0247
Brugia malayi ecdysone receptor 0.003 0.0036 0.0071
Leishmania major PAS-domain containing phosphoglycerate kinase, putative 0.0052 0.0104 0.0195
Trichomonas vaginalis adenylate cyclase, type VII, putative 0.0052 0.0104 0.0205
Mycobacterium tuberculosis Probable cytochrome P450 143 Cyp143 0.0022 0.0013 0.007
Schistosoma mansoni RAR-like nuclear receptor 0.0068 0.0153 0.0241
Trypanosoma brucei phosphatidylinositol 3-related kinase, putative 0.0031 0.0041 0.0081
Toxoplasma gondii aldehyde dehydrogenase 0.0062 0.0134 0.0265
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0037 0.006 0.0119
Loa Loa (eye worm) BEN-1 protein 0.1694 0.5064 1
Echinococcus granulosus TGF beta signal transducer SmadC 0.0043 0.0076 0.0119
Toxoplasma gondii phosphofructokinase domain-containing protein 0.003 0.0039 0.0077
Trichomonas vaginalis phosphofructokinase, putative 0.003 0.0039 0.0077
Onchocerca volvulus 0.0086 0.0208 0.0905
Echinococcus granulosus smad 0.0043 0.0076 0.0119
Leishmania major isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0032 0.0044 0.0077
Trichomonas vaginalis lipid A export ATP-binding/permease protein msba, putative 0.0022 0.0013 0.0025
Trichomonas vaginalis ABC transporter, putative 0.0022 0.0013 0.0025
Trypanosoma brucei alpha tubulin 0.1291 0.3847 0.7598
Schistosoma mansoni hypothetical protein 0.089 0.2634 0.4156
Trypanosoma cruzi Phosphatidylinositol 3-kinase tor1 0.0093 0.0228 0.045
Leishmania major alpha tubulin 0.1291 0.3847 0.7596
Echinococcus granulosus Niemann Pick C1 protein 0.0286 0.0812 0.1281
Trichomonas vaginalis PIKK family atypical protein kinase 0.0093 0.0228 0.045
Echinococcus multilocularis follistatin 0.0059 0.0125 0.0125
Trypanosoma brucei zeta tubulin, putative 0.0709 0.209 0.4127
Trichomonas vaginalis phosphofructokinase, putative 0.0113 0.0288 0.0568
Leishmania major mitogen activated protein kinase, putative,map kinase, putative 0.0104 0.0262 0.0507
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0037 0.006 0.0119
Loa Loa (eye worm) DR-78 0.003 0.0036 0.0071
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.0024 0.0021 0.0041
Onchocerca volvulus 0.0068 0.0153 0.0659
Brugia malayi Smad1 0.0043 0.0076 0.0149
Leishmania major alpha tubulin 0.1291 0.3847 0.7596
Echinococcus granulosus lipoxygenase domain containing protein 0.016 0.0431 0.068
Mycobacterium ulcerans cytochrome P450 144A4 Cyp144A4 0.0022 0.0013 0.007
Mycobacterium tuberculosis holo-[acyl-carrier protein] synthase AcpS (holo-ACP synthase) (CoA:APO-[ACP]pantetheinephosphotransferase) (CoA:APO-[acyl-carrie 0.0027 0.0027 0.0184
Mycobacterium tuberculosis Probable cytochrome P450 136 Cyp136 0.0022 0.0013 0.007
Echinococcus multilocularis mitogen activated protein kinase 0.0104 0.0262 0.0262
Trichomonas vaginalis phosphofructokinase, putative 0.003 0.0039 0.0077
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0026 0.0026 0.0026
Echinococcus multilocularis Ataxin 2, N terminal,domain containing protein 0.0046 0.0087 0.0087
Entamoeba histolytica P-glycoprotein-2, putative 0.0022 0.0013 0.0025
Echinococcus granulosus tubulin alpha 1C chain 0.1291 0.3847 0.607
Trypanosoma cruzi cytochrome P450, putative 0.0068 0.0151 0.0298
Entamoeba histolytica phosphofructokinase, putative 0.0113 0.0288 0.0568
Leishmania major ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative 0.0037 0.006 0.0109
Trypanosoma brucei zeta tubulin 0.0709 0.209 0.4127
Trichomonas vaginalis PIKK family atypical protein kinase 0.0079 0.0187 0.0369
Plasmodium vivax delta tubulin, putative 0.0422 0.1221 0.2405
Echinococcus granulosus tubulin beta 1 chain 0.1694 0.5064 0.7989
Trichomonas vaginalis PIKK family atypical protein kinase 0.005 0.0099 0.0195
Schistosoma mansoni hypothetical protein 0.0833 0.2462 0.3884
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0034 0.0048 0.0096
Leishmania major beta tubulin 0.1694 0.5064 1
Schistosoma mansoni nuclear hormone receptor superfamily protein-related 0.003 0.0036 0.0057
Schistosoma mansoni serine/threonine protein kinase 0.0045 0.0082 0.013
Loa Loa (eye worm) RecQ helicase 0.0042 0.0073 0.0145
Loa Loa (eye worm) hypothetical protein 0.0068 0.0153 0.0301
Echinococcus granulosus multidrug resistance protein 1 0.0022 0.0013 0.002
Echinococcus multilocularis Tubulin beta 2C chain 0.1694 0.5064 0.5064
Echinococcus multilocularis mixed lineage leukemia protein mll 0.0026 0.0026 0.0026
Trypanosoma brucei alpha tubulin 0.1291 0.3847 0.7598
Schistosoma mansoni CREB-binding protein 2 0.02 0.055 0.0867
Toxoplasma gondii NADPH-glutathione reductase 0.0034 0.0048 0.0096
Echinococcus multilocularis tubulin alpha 3 chain 0.1291 0.3847 0.3847
Mycobacterium tuberculosis Probable cytochrome P450 139 Cyp139 0.0022 0.0013 0.007
Schistosoma mansoni coup transcription factor 0.0068 0.0153 0.0241
Loa Loa (eye worm) tubulin alpha chain 0.1291 0.3847 0.7598
Trichomonas vaginalis PIKK family atypical protein kinase 0.0025 0.0022 0.0044
Echinococcus multilocularis tubulin alpha chain 0.1291 0.3847 0.3847
Mycobacterium tuberculosis Probable cytochrome P450 130 Cyp130 0.0022 0.0013 0.007
Echinococcus multilocularis aryl hydrocarbon receptor 0.0052 0.0104 0.0104
Leishmania major phosphopantetheinyl transferase-like protein 0.0027 0.0027 0.0044
Trichomonas vaginalis CMGC family protein kinase 0.0104 0.0262 0.0517
Trypanosoma brucei beta tubulin 0.1694 0.5064 1
Echinococcus multilocularis isocitrate dehydrogenase 0.0032 0.0044 0.0044
Echinococcus granulosus axis inhibition protein axin 0.0044 0.0079 0.0125
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0034 0.0048 0.0096
Echinococcus multilocularis dnaJ subfamily B 0.0833 0.2462 0.2462
Echinococcus multilocularis transcription factor Dp 1 0.0039 0.0064 0.0064
Leishmania major alpha tubulin 0.1291 0.3847 0.7596
Trichomonas vaginalis phosphofructokinase, putative 0.0113 0.0288 0.0568
Trypanosoma brucei PAB1-binding protein , putative 0.0103 0.0259 0.0512
Loa Loa (eye worm) hypothetical protein 0.0024 0.0018 0.0036
Brugia malayi aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase 0.0095 0.0233 0.046
Schistosoma mansoni Smad4 0.0019 0.0004 0.0007
Brugia malayi tubulin alpha-2 chain 0.1291 0.3847 0.7598
Loa Loa (eye worm) cytochrome P450 family protein 0.0022 0.0013 0.0027
Chlamydia trachomatis two component regulatory system sensor histidine kinase 0.0052 0.0104 0.5331
Loa Loa (eye worm) hypothetical protein 0.003 0.0036 0.0071
Mycobacterium tuberculosis Possible cytochrome P450 135B1 Cyp135B1 0.0022 0.0013 0.007
Onchocerca volvulus 0.0244 0.0684 0.3022
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0068 0.0153 0.0301
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0093 0.0228 0.045
Loa Loa (eye worm) Smad1 0.0043 0.0076 0.0149
Echinococcus granulosus nuclear factor of activated T cells 5 0.0075 0.0172 0.0272
Schistosoma mansoni smad 0.0043 0.0076 0.0119
Echinococcus granulosus tubulin gamma 1 chain 0.0966 0.2865 0.452
Mycobacterium tuberculosis Cytochrome P450 51 Cyp51 (CYPL1) (P450-L1A1) (sterol 14-alpha demethylase) (lanosterol 14-alpha demethylase) (P450-14DM) 0.0022 0.0013 0.007
Loa Loa (eye worm) hypothetical protein 0.0261 0.0736 0.1453
Mycobacterium leprae putative cytochrome p450 0.0022 0.0013 0.0036
Plasmodium falciparum LCCL domain-containing protein 0.016 0.0431 0.0842
Schistosoma mansoni hypothetical protein 0.0189 0.0517 0.0816
Schistosoma mansoni tubulin subunit beta 0.1694 0.5064 0.7989
Trichomonas vaginalis abcb9, putative 0.0022 0.0013 0.0025
Mycobacterium tuberculosis Probable aldehyde dehydrogenase 0.0062 0.0134 0.1063
Trypanosoma cruzi apurinic/apyrimidinic endonuclease 0.0019 0.0005 0.001
Brugia malayi bHLH-PAS transcription factor 0.0148 0.0393 0.0777
Echinococcus multilocularis dihydrolipoamide dehydrogenase 0.0034 0.0048 0.0048
Entamoeba histolytica hypothetical protein 0.0189 0.0517 0.1022
Mycobacterium tuberculosis NADPH-dependent mycothiol reductase Mtr 0.0097 0.024 0.1932
Entamoeba histolytica tyrosyl-DNA phosphodiesterase, putative 0.0067 0.0149 0.0294
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0032 0.0044 0.0044
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.0019 0.0005 0.0008
Leishmania major alpha tubulin 0.1291 0.3847 0.7596
Brugia malayi CXXC zinc finger family protein 0.0091 0.0222 0.0439
Loa Loa (eye worm) hypothetical protein 0.016 0.0431 0.0851
Trichomonas vaginalis tubulin, putative 0.0516 0.1506 0.2974
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0098 0.0243 0.0243
Mycobacterium leprae Possible regulatory protein 0.0052 0.0104 0.078
Loa Loa (eye worm) hypothetical protein 0.004 0.0068 0.0134
Loa Loa (eye worm) tubulin beta-2A chain 0.1694 0.5064 1
Mycobacterium tuberculosis Probable cytochrome P450 124 Cyp124 0.0022 0.0013 0.007
Brugia malayi sodium-independent organic anion transporter family protein 0.0086 0.0208 0.0411
Mycobacterium ulcerans cytochrome P450 136A2 Cyp136A2 0.0022 0.0013 0.007
Trichomonas vaginalis tubulin alpha chain, putative 0.0938 0.2781 0.5491
Echinococcus granulosus tubulin subunit TubB 0.1291 0.3847 0.607
Brugia malayi ATP-dependent DNA helicase, RecQ family protein 0.0029 0.0035 0.0069
Loa Loa (eye worm) hypothetical protein 0.1291 0.3847 0.7598
Plasmodium vivax dihydrolipoyl dehydrogenase, mitochondrial, putative 0.0034 0.0048 0.0086
Schistosoma mansoni retinoic acid receptor RXR 0.0068 0.0153 0.0241
Echinococcus multilocularis organic anion transporting polypeptide 30B 0.0086 0.0208 0.0208
Leishmania major beta tubulin 0.1694 0.5064 1
Trypanosoma brucei isocitrate dehydrogenase, putative 0.0032 0.0044 0.0087
Schistosoma mansoni transcription factor LCR-F1 0.0189 0.0517 0.0816
Loa Loa (eye worm) ATP-binding cassette sub-family B member 2 0.0022 0.0013 0.0025
Trypanosoma cruzi ATP-dependent DEAD/H DNA helicase recQ, putative 0.0032 0.0043 0.0084
Trichomonas vaginalis PIKK family atypical protein kinase 0.0069 0.0156 0.0308
Loa Loa (eye worm) hypothetical protein 0.0039 0.0063 0.0125
Trichomonas vaginalis tubulin alpha chain, putative 0.0516 0.1506 0.2974
Brugia malayi nuclear receptor NHR-88 0.0068 0.0153 0.0301
Brugia malayi nuclear receptor RXR 0.0039 0.0063 0.0125
Echinococcus multilocularis beta tubulin 0.1694 0.5064 0.5064
Echinococcus multilocularis Nuclear hormone receptor HR96 0.003 0.0036 0.0036
Plasmodium falciparum ADP-dependent DNA helicase RecQ 0.0039 0.0065 0.012
Echinococcus multilocularis lamin dm0 0.0083 0.0197 0.0197
Brugia malayi Hypothetical 29.7 kDa protein C05D11.5 in chromosome III 0.0021 0.0009 0.0018
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0037 0.006 0.0119
Leishmania major beta tubulin 0.1694 0.5064 1
Trypanosoma brucei tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0067 0.0149 0.0294
Trypanosoma brucei phosphatidylinositol 3-kinase, putative 0.0031 0.0041 0.0081
Schistosoma mansoni agrin 0.0059 0.0125 0.0197
Leishmania major alpha tubulin 0.1291 0.3847 0.7596
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0032 0.0043 0.0043
Schistosoma mansoni jun-related protein 0.0218 0.0606 0.0956
Loa Loa (eye worm) hypothetical protein 0.0068 0.0153 0.0301
Echinococcus granulosus lamin dm0 0.0083 0.0197 0.0311
Echinococcus multilocularis expressed conserved protein 0.0188 0.0516 0.0516
Echinococcus granulosus sterol regulatory element binding protein 0.0086 0.0207 0.0326
Mycobacterium tuberculosis Cell division protein FtsZ 0.0422 0.1221 1
Trypanosoma brucei FAT domain/Rapamycin binding domain/Phosphatidylinositol 3- and 4-kinase, putative 0.0039 0.0064 0.0125
Echinococcus granulosus tyrosyl DNA phosphodiesterase 1 0.0067 0.0149 0.0235
Schistosoma mansoni tubulin subunit alpha 0.1291 0.3847 0.607
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0021 0.0009 0.0018
Mycobacterium ulcerans cytochrome P450 185A4 Cyp185A4 0.0068 0.0151 0.1202
Echinococcus granulosus tubulin alpha 1C chain 0.1291 0.3847 0.607
Brugia malayi cytochrome P450 0.0022 0.0013 0.0027
Trichomonas vaginalis mercuric reductase, putative 0.0034 0.0048 0.0096
Echinococcus multilocularis phosphatidylinositol 3 and 4 kinase 0.0031 0.0041 0.0041
Schistosoma mansoni nuclear hormone receptor 0.003 0.0036 0.0057
Echinococcus granulosus FTZ F1 alpha 0.0068 0.0153 0.0241
Giardia lamblia Beta tubulin 0.1694 0.5064 1
Echinococcus multilocularis 0.0022 0.0013 0.0013
Brugia malayi hypothetical protein 0.0086 0.0208 0.0411
Mycobacterium ulcerans cytochrome P450 187A5 Cyp187A5 0.0022 0.0013 0.007
Loa Loa (eye worm) hypothetical protein 0.0052 0.0104 0.0205
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0034 0.0048 0.0096
Trichomonas vaginalis phosphofructokinase, putative 0.003 0.0039 0.0077
Trichomonas vaginalis ATP-binding cassette transporter, putative 0.0022 0.0013 0.0025
Plasmodium falciparum glutathione reductase 0.0034 0.0048 0.0086
Chlamydia trachomatis holo [acyl-carrier protein] synthase 0.0027 0.0027 0.0862
Trypanosoma cruzi trypanothione reductase, putative 0.0034 0.0048 0.0096
Loa Loa (eye worm) BEN-1 protein 0.1694 0.5064 1
Brugia malayi hypothetical protein 0.016 0.0431 0.0851
Loa Loa (eye worm) hypothetical protein 0.0019 0.0004 0.0008
Schistosoma mansoni blooms syndrome DNA helicase 0.0027 0.0029 0.0045
Onchocerca volvulus 0.016 0.0431 0.1896
Mycobacterium ulcerans aldehyde dehydrogenase 0.0062 0.0134 0.1063
Echinococcus multilocularis mitogen activated protein kinase 3 0.0104 0.0262 0.0262
Echinococcus multilocularis cytoplasmic intermediate filament protein 0.004 0.0068 0.0068
Trichomonas vaginalis conserved hypothetical protein 0.0044 0.0079 0.0157
Trichomonas vaginalis lipid A export ATP-binding/permease protein msba, putative 0.0022 0.0013 0.0025
Brugia malayi Kazal-type serine protease inhibitor domain containing protein 0.0059 0.0125 0.0247
Echinococcus multilocularis ATP dependent DNA helicase Q5 0.0029 0.0035 0.0035
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0098 0.0243 0.0479
Trichomonas vaginalis PIKK family atypical protein kinase 0.005 0.0098 0.0194
Entamoeba histolytica phosphofructokinase, putative 0.0113 0.0288 0.0568
Plasmodium falciparum multidrug resistance protein 1 0.0022 0.0013 0.0015
Loa Loa (eye worm) raf kinase 0.0045 0.0082 0.0162
Loa Loa (eye worm) jmjC domain-containing protein 0.0065 0.0143 0.0282
Echinococcus granulosus Solute carrier organic anion transporter family 0.0086 0.0208 0.0328
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.0068 0.0153 0.0301
Trichomonas vaginalis PIKK family atypical protein kinase 0.0074 0.017 0.0336
Trichomonas vaginalis ABC transporter, putative 0.0022 0.0013 0.0025
Echinococcus granulosus beta-adrenergic receptor kinase 0.0045 0.0082 0.013
Brugia malayi regulator of G-protein signaling rgs-7 0.0044 0.0079 0.0157
Entamoeba histolytica hypothetical protein 0.0044 0.0079 0.0157
Loa Loa (eye worm) agrin synaptic family protein 0.0059 0.0125 0.0247
Leishmania major ATP-dependent phosphofructokinase 0.0113 0.0288 0.0559
Echinococcus granulosus lamin 0.0083 0.0197 0.0311
Loa Loa (eye worm) RGS-3 protein 0.0044 0.0079 0.0157
Loa Loa (eye worm) hypothetical protein 0.003 0.0036 0.0071
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0021 0.0009 0.0018
Leishmania major beta tubulin 0.1694 0.5064 1
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0068 0.0153 0.0153
Trichomonas vaginalis conserved hypothetical protein 0.0021 0.0009 0.0018
Echinococcus multilocularis Nuclear hormone receptor HR96 0.003 0.0036 0.0036
Trichomonas vaginalis PIKK family atypical protein kinase 0.005 0.0098 0.0194
Schistosoma mansoni hypothetical protein 0.0022 0.0013 0.0021
Brugia malayi nuclear receptor NHR-67 0.003 0.0036 0.0071
Loa Loa (eye worm) hypothetical protein 0.0869 0.2573 0.5081
Leishmania major alpha tubulin 0.1291 0.3847 0.7596
Echinococcus granulosus multidrug resistance protein 1 0.0022 0.0013 0.002
Echinococcus granulosus nuclear receptor subfamily 1 group D 0.0039 0.0063 0.01
Schistosoma mansoni cpg binding protein 0.0096 0.0238 0.0375
Loa Loa (eye worm) hypothetical protein 0.0098 0.0243 0.0479
Loa Loa (eye worm) hypothetical protein 0.0028 0.003 0.006
Plasmodium vivax multidomain scavenger receptor, putative 0.016 0.0431 0.0842
Brugia malayi 6-phosphofructokinase 0.0113 0.0288 0.0568
Loa Loa (eye worm) hypothetical protein 0.0086 0.0208 0.0411
Schistosoma mansoni nuclear receptor nhr-48 0.003 0.0036 0.0057
Schistosoma mansoni serine/threonine protein kinase 0.0104 0.0262 0.0413
Schistosoma mansoni regulator of G protein signaling 17 19 20 (rgs17 19 20) 0.0044 0.0079 0.0125
Leishmania major beta tubulin 0.1694 0.5064 1
Trichomonas vaginalis lipid A export ATP-binding/permease protein msba, putative 0.0022 0.0013 0.0025
Entamoeba histolytica hypothetical protein 0.0189 0.0517 0.1022
Echinococcus granulosus ecdysone induced protein 78C 0.0068 0.0153 0.0241
Echinococcus granulosus beta tubulin 0.1694 0.5064 0.7989
Entamoeba histolytica exodeoxyribonuclease III, putative 0.0019 0.0005 0.001
Loa Loa (eye worm) beta-tubulin 0.1694 0.5064 1
Loa Loa (eye worm) doublecortin family protein 0.016 0.0431 0.0851
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0026 0.0026 0.0041
Brugia malayi regulator of G-protein signaling egl-10 0.0044 0.0079 0.0157
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.0068 0.0153 0.0241
Schistosoma mansoni Smad4 0.0043 0.0076 0.0119
Toxoplasma gondii Kazal-type serine protease inhibitor domain-containing protein 0.0059 0.0125 0.0247
Onchocerca volvulus 0.0764 0.2254 1
Mycobacterium ulcerans cytochrome P450 143A3 Cyp143A3 0.0022 0.0013 0.007
Toxoplasma gondii 6-phosphofructokinase 0.003 0.0039 0.0077
Echinococcus multilocularis sterol regulatory element binding protein 0.0086 0.0207 0.0207
Leishmania major target of rapamycin (TOR) kinase 2, putative 0.0093 0.0228 0.044
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0032 0.0044 0.0044
Trichomonas vaginalis phosphofructokinase, putative 0.0113 0.0288 0.0568
Plasmodium falciparum ataxin-2 like protein, putative 0.0103 0.0259 0.0503
Trichomonas vaginalis PIKK family atypical protein kinase 0.0074 0.017 0.0336
Chlamydia trachomatis fructose-6-phosphate phosphotransferase 0.003 0.0039 0.1546
Brugia malayi Thioredoxin reductase 0.0097 0.024 0.0474
Trichomonas vaginalis conserved hypothetical protein 0.0021 0.0009 0.0018
Toxoplasma gondii tubulin/FtsZ family, GTPase domain-containing protein 0.0938 0.2781 0.5491
Toxoplasma gondii tubulin/FtsZ family, GTPase domain-containing protein 0.0449 0.1304 0.2576
Trypanosoma cruzi STE/STE11 serine/threonine-protein kinase, putative 0.0053 0.0106 0.021
Schistosoma mansoni hypothetical protein 0.0083 0.0197 0.0311
Echinococcus granulosus Polycystic kidney disease protein 0.016 0.0431 0.068
Echinococcus granulosus CREB binding protein 0.0033 0.0046 0.0072
Leishmania major tyrosyl-DNA phosphodiesterase 1 0.0067 0.0149 0.0285
Brugia malayi Cytochrome P450 family protein 0.0068 0.0151 0.0298
Plasmodium vivax tubulin alpha chain, putative 0.1291 0.3847 0.7596
Giardia lamblia Alpha-tubulin 0.1291 0.3847 0.7596
Echinococcus granulosus histone lysine methyltransferase setb 0.0098 0.0243 0.0383
Brugia malayi MH1 domain containing protein 0.0024 0.0018 0.0036
Echinococcus granulosus Regulator of G protein signaling 20 0.0044 0.0079 0.0125
Trypanosoma cruzi STE group serine/threonine-protein kinase, putative 0.0053 0.0106 0.021
Onchocerca volvulus 0.0022 0.0013 0.0036
Trichomonas vaginalis conserved hypothetical protein 0.0021 0.0009 0.0018
Schistosoma mansoni NADP-specific isocitrate dehydrogenase 0.0032 0.0044 0.0069
Echinococcus granulosus mothers against decapentaplegic 2 0.0019 0.0004 0.0007
Trichomonas vaginalis tubulin gamma chain, putative 0.0966 0.2865 0.5657
Echinococcus granulosus NADP dependent isocitrate dehydrogenase 0.0032 0.0044 0.0069
Mycobacterium tuberculosis Probable cytochrome P450 132 Cyp132 0.0022 0.0013 0.007
Loa Loa (eye worm) phosphatidylinositol 3 0.0093 0.0228 0.045
Loa Loa (eye worm) sodium-independent organic anion transporter 0.0086 0.0208 0.0411
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0333 0.0952 0.1879
Onchocerca volvulus 0.0058 0.0123 0.0526
Echinococcus multilocularis CREB binding protein 0.0033 0.0046 0.0046
Loa Loa (eye worm) hypothetical protein 0.0068 0.0153 0.0301
Plasmodium falciparum tubulin delta chain, putative 0.0422 0.1221 0.2405
Loa Loa (eye worm) hypothetical protein 0.002 0.0006 0.0012
Trichomonas vaginalis multidrug resistance protein 1, 2, putative 0.0022 0.0013 0.0025
Brugia malayi dihydrolipoyl dehydrogenase, mitochondrial precursor, putative 0.0034 0.0048 0.0096
Toxoplasma gondii LsmAD domain-containing protein 0.0103 0.0259 0.0512
Loa Loa (eye worm) nuclear receptor NHR-67 0.003 0.0036 0.0071
Trichomonas vaginalis PIKK family atypical protein kinase 0.005 0.0099 0.0195
Echinococcus multilocularis retinoic acid receptor rxr beta a retinoic acid receptor rxr alpha a retinoic acid receptor rxr alpha 0.003 0.0036 0.0036
Trichomonas vaginalis multidrug resistance protein 1, 2, putative 0.0022 0.0013 0.0025
Trypanosoma cruzi epsilon tubulin, putative 0.0966 0.2864 0.5655
Brugia malayi conserved hypotetical protein 0.003 0.0036 0.0071
Mycobacterium ulcerans cytochrome P450 143A4 Cyp143A4 0.0022 0.0013 0.007
Schistosoma mansoni hypothetical protein 0.0271 0.0766 0.1208
Echinococcus granulosus tubulin alpha 3 chain 0.1291 0.3847 0.607
Schistosoma mansoni tubulin subunit beta 0.1694 0.5064 0.7989
Plasmodium falciparum alpha tubulin 2 0.1291 0.3847 0.7596
Brugia malayi Niemann-Pick C1 protein precursor 0.02 0.0552 0.1091
Brugia malayi hypothetical protein 0.0189 0.0517 0.1022
Brugia malayi hypothetical protein 0.0067 0.0149 0.0294
Brugia malayi ABC transporter family protein 0.0022 0.0013 0.0025
Schistosoma mansoni ubiquitin-specific peptidase 2 (C19 family) 0.0037 0.006 0.0095
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0034 0.0048 0.0096
Echinococcus granulosus Transcription factor JmjC domain containing protein 0.006 0.0127 0.02
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.003 0.0036 0.0141
Schistosoma mansoni zinc finger protein 0.003 0.0036 0.0057
Echinococcus multilocularis tubulin gamma 1 chain 0.0966 0.2865 0.2865
Plasmodium falciparum tubulin gamma chain 0.0966 0.2865 0.5653
Schistosoma mansoni tubulin subunit gamma 0.0966 0.2865 0.452
Mycobacterium tuberculosis Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras 0.0246 0.069 0.5633
Echinococcus multilocularis A kinase anchor protein 10, mitochondrial 0.0044 0.0079 0.0079
Mycobacterium leprae conserved hypothetical protein 0.0027 0.0027 0.015
Brugia malayi Regulator of G protein signaling domain containing protein 0.0044 0.0079 0.0157
Trichomonas vaginalis tubulin epsilon chain, putative 0.1291 0.3847 0.7598
Echinococcus granulosus geminin 0.089 0.2634 0.4156
Echinococcus granulosus transcription factor Dp 1 0.0039 0.0064 0.0101
Entamoeba histolytica P-glycoprotein 5, putative 0.0022 0.0013 0.0025
Brugia malayi Tubulin beta-1 chain 0.1694 0.5064 1
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0068 0.0153 0.0301
Loa Loa (eye worm) hypothetical protein 0.003 0.0036 0.0071
Echinococcus multilocularis tubulin alpha 1C chain 0.1291 0.3847 0.3847
Plasmodium falciparum ATP-dependent 6-phosphofructokinase 0.003 0.0039 0.0067
Echinococcus multilocularis Aryl hydrocarbon receptor nuclear 0.0052 0.0104 0.0104
Echinococcus multilocularis bloom syndrome protein 0.0042 0.0073 0.0073
Brugia malayi Bloom's syndrome protein homolog 0.0042 0.0073 0.0145
Trichomonas vaginalis ABC transporter, half transporter, putative 0.0022 0.0013 0.0025
Leishmania major alpha tubulin 0.1291 0.3847 0.7596
Schistosoma mansoni tubulin subunit alpha 0.1291 0.3847 0.607
Leishmania major protein kinase, putative 0.0053 0.0106 0.0201
Mycobacterium tuberculosis Probable reductase 0.0221 0.0616 0.5019
Entamoeba histolytica pyrophosphate-dependent phosphofructokinase 0.003 0.0039 0.0077
Echinococcus granulosus mixed lineage leukemia protein mll 0.0026 0.0026 0.0041
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.0333 0.0952 0.1879
Trichomonas vaginalis abcb9, putative 0.0022 0.0013 0.0025
Onchocerca volvulus 0.016 0.0431 0.1896
Loa Loa (eye worm) hypothetical protein 0.0068 0.0153 0.0301
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.0068 0.0153 0.0301
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0098 0.0243 0.0383
Plasmodium vivax tubulin epsilon chain, putative 0.0966 0.2864 0.5651
Loa Loa (eye worm) alpha-tubulin 0.1291 0.3847 0.7598
Entamoeba histolytica phosphatidylinositol3-kinaseTor2, putative 0.0093 0.0228 0.045
Echinococcus multilocularis 6 phosphofructokinase 0.0113 0.0288 0.0288
Giardia lamblia Sgs1 DNA helicase, putative 0.0029 0.0035 0.0059
Loa Loa (eye worm) hypothetical protein 0.0039 0.0063 0.0125
Trypanosoma brucei hypothetical protein, conserved 0.0027 0.0027 0.0054
Entamoeba histolytica FKBP-rapamycin associated protein (FRAP), putative 0.0093 0.0228 0.045
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.0068 0.0153 0.0301
Entamoeba histolytica hypothetical protein 0.0044 0.0079 0.0157
Echinococcus granulosus mitogen activated protein kinase 0.0104 0.0262 0.0413
Trypanosoma cruzi cytochrome p450-like protein, putative 0.0022 0.0013 0.0027
Trypanosoma brucei alpha tubulin, putative 0.0516 0.1506 0.2974
Trichomonas vaginalis tubulin beta chain, putative 0.1291 0.3847 0.7598
Echinococcus granulosus beta tubulin 0.1694 0.5064 0.7989
Trichomonas vaginalis conserved hypothetical protein 0.0021 0.0009 0.0018
Leishmania major aldehyde dehydrogenase, mitochondrial precursor 0.0062 0.0134 0.0256
Loa Loa (eye worm) MH1 domain-containing protein 0.0019 0.0004 0.0009
Echinococcus multilocularis nuclear receptor nhr 48 0.003 0.0036 0.0036
Echinococcus multilocularis ATP binding cassette sub family B 0.0021 0.0012 0.0012
Plasmodium falciparum tubulin beta chain 0.1694 0.5064 1
Echinococcus granulosus Protein patched homolog 1 0.0086 0.0207 0.0326
Loa Loa (eye worm) hypothetical protein 0.016 0.0431 0.0851
Echinococcus multilocularis isocitrate dehydrogenase 2 (NADP+) 0.0032 0.0044 0.0044
Toxoplasma gondii tubulin, putative 0.0027 0.003 0.0059
Plasmodium falciparum thioredoxin reductase 0.0034 0.0048 0.0086
Schistosoma mansoni multidrug resistance protein 0.0022 0.0013 0.002
Giardia lamblia NADH oxidase lateral transfer candidate 0.0034 0.0048 0.0086
Loa Loa (eye worm) hypothetical protein 0.0068 0.0153 0.0301
Trypanosoma cruzi phosphatidylinositol 3-related kinase, putative 0.0031 0.0041 0.0081
Echinococcus granulosus ATP binding cassette subfamily B MDR:TAP 0.0022 0.0013 0.002
Echinococcus granulosus Smad4 0.0043 0.0076 0.0119
Schistosoma mansoni patched 1 0.0086 0.0207 0.0326
Loa Loa (eye worm) hypothetical protein 0.0059 0.0125 0.0247
Entamoeba histolytica tubulin family protein 0.1694 0.5064 1
Trichomonas vaginalis PIKK family atypical protein kinase 0.0074 0.017 0.0336
Loa Loa (eye worm) histone methyltransferase 0.0032 0.0043 0.0084
Echinococcus multilocularis Niemann Pick C1 protein 0.02 0.0552 0.0552
Toxoplasma gondii transporter, major facilitator family protein 0.0086 0.0208 0.0411
Plasmodium falciparum tubulin epsilon chain, putative 0.0966 0.2864 0.5651
Loa Loa (eye worm) tubulin beta chain 0.0422 0.1221 0.2412
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0034 0.0048 0.0096
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0021 0.0009 0.0018
Loa Loa (eye worm) MH1 domain-containing protein 0.0043 0.0076 0.0149
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.0019 0.0005 0.0005
Brugia malayi jmjC domain containing protein 0.0065 0.0143 0.0282
Mycobacterium leprae PROBABLE 6-PHOSPHOFRUCTOKINASE PFKA (PHOSPHOHEXOKINASE) (PHOSPHOFRUCTOKINASE) 0.0113 0.0288 0.2298
Schistosoma mansoni multidrug resistance protein 0.0022 0.0013 0.002
Leishmania major target of rapamycin (TOR) kinase 1, putative 0.0093 0.0228 0.044
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0037 0.006 0.0119
Schistosoma mansoni lamin 0.0083 0.0197 0.0311
Trichomonas vaginalis tubulin alpha chain, putative 0.1694 0.5064 1
Echinococcus multilocularis FKBP12 rapamycin complex associated protein 0.0093 0.0228 0.0228
Loa Loa (eye worm) cytoplasmic intermediate filament protein 0.0044 0.0081 0.016
Plasmodium vivax multidrug resistance protein 1, putative 0.0022 0.0013 0.0015
Leishmania major 2-oxoglutarate dehydrogenase, e3 component, lipoamidedehydrogenase-like protein 0.0034 0.0048 0.0086
Echinococcus granulosus ubiquitin specific protease 41 0.0037 0.006 0.0095
Echinococcus granulosus CREB binding protein 0.0123 0.0319 0.0503
Brugia malayi hypothetical protein 0.0039 0.0063 0.0125
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0021 0.0009 0.0018
Loa Loa (eye worm) hypothetical protein 0.0086 0.0208 0.0411
Loa Loa (eye worm) hypothetical protein 0.0029 0.0035 0.0069
Loa Loa (eye worm) MH2 domain-containing protein 0.0043 0.0076 0.0149
Brugia malayi Tubulin beta chain 0.0516 0.1506 0.2974
Echinococcus granulosus RUN 0.016 0.0431 0.068
Brugia malayi hypothetical protein 0.0044 0.0079 0.0157
Entamoeba histolytica tubulin gamma chain 0.0966 0.2865 0.5657
Trypanosoma brucei cytochrome P450, putative 0.0068 0.0151 0.0298
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.0058 0.0123 0.0243
Loa Loa (eye worm) phosphatidylinositol 3 0.0031 0.0041 0.0081
Trichomonas vaginalis conserved hypothetical protein 0.0021 0.0009 0.0018
Trichomonas vaginalis tubulin gamma chain, putative 0.0422 0.1221 0.2412
Mycobacterium ulcerans cytochrome P450 105Q4 Cyp105Q4 0.0022 0.0013 0.007
Entamoeba histolytica P-glyco protein 6, putative 0.0022 0.0013 0.0025
Trichomonas vaginalis multidrug resistance protein 1, 2, putative 0.0022 0.0013 0.0025
Brugia malayi nuclear receptor NHR-88 0.003 0.0036 0.0071
Toxoplasma gondii protease inhibitor PI2 0.0059 0.0125 0.0247
Onchocerca volvulus Putative hydroxypyruvate isomerase 0.0021 0.0009 0.0021
Echinococcus multilocularis multidrug resistance protein 1 0.0022 0.0013 0.0013
Loa Loa (eye worm) MH2 domain-containing protein 0.0626 0.1837 0.3628
Trichomonas vaginalis adenylate and guanylate cyclases, putative 0.0052 0.0104 0.0205
Mycobacterium ulcerans cytochrome p450 150 cyp150 0.0022 0.0013 0.007
Echinococcus granulosus aryl hydrocarbon receptor 0.0052 0.0104 0.0163
Schistosoma mansoni fkbp-rapamycin associated protein 0.0018 0.000000014696 0.000000023184
Brugia malayi MH2 domain containing protein 0.0626 0.1837 0.3628
Toxoplasma gondii non-specific serine/threonine protein kinase 0.002 0.0006 0.0012
Trichomonas vaginalis PIKK family atypical protein kinase 0.0069 0.0156 0.0308
Loa Loa (eye worm) phosphofructokinase 0.0113 0.0288 0.0568
Toxoplasma gondii ABC transporter transmembrane region domain-containing protein 0.0022 0.0013 0.0025
Echinococcus multilocularis axis inhibition protein axin 0.0044 0.0079 0.0079
Mycobacterium ulcerans cytochrome P450 51B1 Cyp51B1 0.0022 0.0013 0.007
Loa Loa (eye worm) hypothetical protein 0.0044 0.0079 0.0157
Loa Loa (eye worm) hypoxia-induced factor 1 0.0618 0.1813 0.3581
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0333 0.0952 0.1879
Schistosoma mansoni Tr4/Tr2 (homologue) 0.0068 0.0153 0.0241
Giardia lamblia Alpha-tubulin 0.1291 0.3847 0.7596
Loa Loa (eye worm) CMGC/MAPK/ERK1 protein kinase 0.0104 0.0262 0.0517
Trichomonas vaginalis PIKK family atypical protein kinase 0.0031 0.0041 0.0081
Schistosoma mansoni DNA helicase recq1 0.0029 0.0035 0.0055
Loa Loa (eye worm) hypothetical protein 0.0038 0.0063 0.0125
Trichomonas vaginalis DNA helicase recq, putative 0.0032 0.0043 0.0084
Loa Loa (eye worm) hypothetical protein 0.003 0.0036 0.0071
Echinococcus granulosus regulator of G protein signaling 7 0.0044 0.0079 0.0125
Trichomonas vaginalis guanylate cyclase, putative 0.0052 0.0104 0.0205
Plasmodium vivax apurinic/apyrimidinic endonuclease Apn1, putative 0.0078 0.0183 0.0353
Mycobacterium ulcerans flavoprotein disulfide reductase 0.0034 0.0048 0.0358
Trichomonas vaginalis lipid A export ATP-binding/permease protein msba, putative 0.0022 0.0013 0.0025
Echinococcus granulosus tubulin delta chain 0.0422 0.1221 0.1927
Schistosoma mansoni aldehyde dehydrogenase 0.0062 0.0134 0.0212
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0021 0.0009 0.0018
Leishmania major target of rapamycin kinase (TOR) kinase 3 0.0074 0.017 0.0327
Trypanosoma brucei Phosphatidylinositol 3-kinase tor1 0.0093 0.0228 0.045
Trichomonas vaginalis ATP-binding cassette transporter, putative 0.0022 0.0013 0.0025
Loa Loa (eye worm) hypothetical protein 0.0019 0.0004 0.0009
Chlamydia trachomatis fructose-6-phosphate phosphotransferase 0.003 0.0039 0.1546
Echinococcus granulosus Ataxin 2 N terminaldomain containing protein 0.0046 0.0087 0.0137
Trypanosoma brucei beta tubulin 0.1694 0.5064 1
Echinococcus granulosus tubulin subunit beta 0.1694 0.5064 0.7989
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0068 0.0153 0.0301
Brugia malayi orphan nuclear receptor NR2E1 0.003 0.0036 0.0071
Echinococcus granulosus jun protein 0.0269 0.0758 0.1196
Brugia malayi intermediate filament protein 0.0083 0.0197 0.039
Trichomonas vaginalis conserved hypothetical protein 0.0044 0.0079 0.0157
Echinococcus granulosus single minded 2 0.0148 0.0393 0.062
Echinococcus multilocularis expressed protein 0.0762 0.2249 0.2249
Echinococcus granulosus ATP binding cassette subfamily B MDR:TAP 0.0022 0.0013 0.002
Mycobacterium ulcerans fructose-bisphosphate aldolase 0.0162 0.0438 0.3558
Trichomonas vaginalis tubulin gamma chain, putative 0.1694 0.5064 1
Echinococcus granulosus ATP dependent DNA helicase Q1 0.0029 0.0035 0.0055
Schistosoma mansoni thyroid hormone receptor 0.0068 0.0153 0.0241
Echinococcus multilocularis lamin 0.0083 0.0197 0.0197
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.0068 0.0153 0.0153
Loa Loa (eye worm) abnormal chemotaxis protein 14 0.0086 0.0207 0.0408
Loa Loa (eye worm) hypothetical protein 0.0392 0.113 0.2232
Loa Loa (eye worm) isocitrate dehydrogenase 0.0032 0.0044 0.0087
Trypanosoma cruzi cytochrome P450, putative 0.0068 0.0151 0.0298
Echinococcus multilocularis Tubulin alpha 1 chain 0.1291 0.3847 0.3847
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.0068 0.0153 0.0241
Echinococcus granulosus expressed protein 0.0762 0.2249 0.3548
Loa Loa (eye worm) hypothetical protein 0.0086 0.0208 0.0411
Trichomonas vaginalis DNA helicase recq, putative 0.0042 0.0073 0.0145
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0068 0.0153 0.0153
Trypanosoma cruzi Lanosterol 14-alpha demethylase 0.0022 0.0013 0.0027
Loa Loa (eye worm) G protein signaling regulator EGL-10 0.0044 0.0079 0.0157
Trypanosoma brucei beta tubulin 0.0938 0.2781 0.5491
Leishmania major beta tubulin 0.1694 0.5064 1
Giardia lamblia Kinase, CMGC MAPK 0.0104 0.0262 0.0507
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0189 0.0517 0.0517
Onchocerca volvulus Putative organic anion transporter 0.0086 0.0208 0.0905
Loa Loa (eye worm) aryl Hydrocarbon receptor Associated protein family member 0.0052 0.0104 0.0205
Brugia malayi PXA domain containing protein 0.0044 0.0079 0.0157
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative 0.0019 0.0005 0.001
Brugia malayi A-kinase anchor protein 10, precursor 0.0044 0.0079 0.0157
Trichomonas vaginalis conserved hypothetical protein 0.0021 0.0009 0.0018
Entamoeba histolytica Niemann-Pick C1 protein, putative 0.02 0.0552 0.1091
Schistosoma mansoni smdr2 0.0022 0.0013 0.002
Echinococcus granulosus phosphatidylinositol 3 and 4 kinase 0.0031 0.0041 0.0065
Trypanosoma brucei dihydrolipoamide dehydrogenase, point mutation 0.0034 0.0048 0.0096
Mycobacterium ulcerans cytochrome P450 191A3 Cyp191A3 0.0022 0.0013 0.007
Entamoeba histolytica recQ family helicase, putative 0.0032 0.0043 0.0084
Brugia malayi MAP kinase sur-1 0.0104 0.0262 0.0517
Brugia malayi MH2 domain containing protein 0.0043 0.0076 0.0149
Echinococcus multilocularis regulator of G protein signaling 0.0044 0.0079 0.0079
Trichomonas vaginalis PIKK family atypical protein kinase 0.0031 0.0041 0.0081
Echinococcus granulosus Peptidase C19 ubiquitin carboxyl terminal hydrolase 2 0.0037 0.006 0.0095
Trichomonas vaginalis tubulin beta chain, putative 0.1291 0.3847 0.7598
Loa Loa (eye worm) MH2 domain-containing protein 0.0019 0.0004 0.0009
Schistosoma mansoni nuclear receptor 0.003 0.0036 0.0057
Brugia malayi alpha-tubulin 0.1291 0.3847 0.7598
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0031 0.0041 0.0081
Echinococcus granulosus thyroid hormone receptor alpha 0.003 0.0036 0.0057
Trypanosoma cruzi MFS transporter, putative 0.0086 0.0208 0.0411
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0034 0.0048 0.0096
Loa Loa (eye worm) hypothetical protein 0.0039 0.0063 0.0125
Toxoplasma gondii isocitrate dehydrogenase 0.0032 0.0044 0.0087
Trypanosoma cruzi isocitrate dehydrogenase, putative 0.0032 0.0044 0.0087
Mycobacterium ulcerans cell division protein FtsZ 0.0422 0.1221 1
Trichomonas vaginalis conserved hypothetical protein 0.0044 0.0079 0.0157
Brugia malayi MH2 domain containing protein 0.0019 0.0004 0.0009
Echinococcus granulosus Tubulin beta 2C chain 0.1694 0.5064 0.7989
Echinococcus granulosus regulator of G protein signaling 7 0.0044 0.0079 0.0125
Plasmodium vivax isocitrate dehydrogenase [NADP], mitochondrial, putative 0.0032 0.0044 0.0077
Echinococcus multilocularis tubulin, beta 4A class IVa 0.1694 0.5064 0.5064
Brugia malayi PXA domain containing protein 0.0044 0.0079 0.0157
Echinococcus granulosus Tubulin beta 2C chain 0.1694 0.5064 0.7989
Brugia malayi hypothetical protein 0.067 0.197 0.3891
Echinococcus granulosus bloom syndrome protein 0.0042 0.0073 0.0116
Entamoeba histolytica P-glycoprotein-5 0.0022 0.0013 0.0025
Trypanosoma brucei Lanosterol 14-alpha demethylase 0.0022 0.0013 0.0027
Brugia malayi MH1 domain containing protein 0.0043 0.0076 0.0149
Giardia lamblia Gamma tubulin 0.0966 0.2865 0.5653
Echinococcus granulosus Nuclear hormone receptor HR96 0.003 0.0036 0.0057
Mycobacterium tuberculosis Probable oxidoreductase 0.0246 0.069 0.5633
Trypanosoma brucei protein kinase, putative 0.0104 0.0262 0.0517
Mycobacterium tuberculosis Probable cytochrome P450 141 Cyp141 0.0022 0.0013 0.007
Leishmania major acetoin dehydrogenase e3 component-like protein 0.0034 0.0048 0.0086
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0021 0.0009 0.0018
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0068 0.0153 0.0241
Loa Loa (eye worm) hypothetical protein 0.0086 0.0208 0.0411
Trypanosoma brucei beta tubulin 0.1694 0.5064 1
Echinococcus multilocularis hypothetical protein 0.1291 0.3847 0.3847
Mycobacterium tuberculosis Probable cytochrome P450 123 Cyp123 0.0022 0.0013 0.007
Schistosoma mansoni Smad4 0.0019 0.0004 0.0007
Brugia malayi Pax transcription factor protein 2 0.0244 0.0684 0.1351
Trypanosoma cruzi trypanothione reductase, putative 0.0097 0.024 0.0474
Onchocerca volvulus 0.0201 0.0554 0.2442
Leishmania major lanosterol 14-alpha-demethylase, putative 0.0022 0.0013 0.0017
Trichomonas vaginalis PIKK family atypical protein kinase 0.005 0.0098 0.0194
Trichomonas vaginalis conserved hypothetical protein 0.0044 0.0079 0.0157
Schistosoma mansoni aryl hydrocarbon receptor 0.02 0.055 0.0868
Mycobacterium ulcerans sugar phosphate isomerases/epimerases 0.0021 0.0009 0.0034
Loa Loa (eye worm) transcription factor SMAD2 0.0626 0.1837 0.3628
Plasmodium falciparum thioredoxin reductase 0.0097 0.024 0.0465
Echinococcus granulosus cytochrome P450 2K1 0.0022 0.0013 0.0021
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.0068 0.0153 0.0153
Loa Loa (eye worm) hypothetical protein 0.0022 0.0013 0.0025
Mycobacterium ulcerans hypothetical protein 0.0021 0.0009 0.0034
Schistosoma mansoni hypothetical protein 0.0058 0.0123 0.0194
Echinococcus multilocularis nuclear factor of activated T cells 5 0.0075 0.0172 0.0172
Echinococcus multilocularis survival motor neuron protein 1 0.0286 0.081 0.081
Echinococcus multilocularis thioredoxin glutathione reductase 0.0097 0.024 0.024
Schistosoma mansoni hepatocyte nuclear factor 4-alpha (hnf-4-alpha) 0.003 0.0036 0.0057
Leishmania major cytochrome p450-like protein 0.0068 0.0151 0.0289
Loa Loa (eye worm) hypothetical protein 0.0083 0.0197 0.039
Schistosoma mansoni smad 0.0019 0.0004 0.0007
Toxoplasma gondii alpha tubulin TUBA1 0.1291 0.3847 0.7598
Toxoplasma gondii isocitrate dehydrogenase 0.0032 0.0044 0.0087
Trichomonas vaginalis tubulin alpha-1 chain, putative 0.1291 0.3847 0.7598
Trypanosoma brucei mitogen activated protein kinase 4, putative 0.0104 0.0262 0.0517
Brugia malayi nuclear hormone receptor family member odr-7 0.003 0.0036 0.0071
Trypanosoma brucei ATP-dependent DEAD/H DNA helicase recQ, putative 0.0032 0.0043 0.0084
Trichomonas vaginalis conserved hypothetical protein 0.002 0.0006 0.0012
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0026 0.0026 0.0041
Trypanosoma cruzi zeta tubulin, putative 0.0709 0.209 0.4127
Trypanosoma cruzi Lanosterol 14-alpha demethylase 0.0022 0.0013 0.0027
Trichomonas vaginalis tubulin epsilon chain, putative 0.1694 0.5064 1
Echinococcus granulosus regulator of G protein signaling 3 0.0044 0.0079 0.0125
Echinococcus multilocularis Smad4 0.0043 0.0076 0.0076
Plasmodium falciparum apurinic/apyrimidinic endonuclease Apn1, putative 0.0078 0.0183 0.0353
Echinococcus multilocularis raf serine:threonine protein kinase 0.0045 0.0082 0.0082
Trypanosoma brucei trypanothione reductase 0.0097 0.024 0.0474
Schistosoma mansoni polycystin 1-related 0.016 0.0431 0.068
Plasmodium falciparum dihydrolipoyl dehydrogenase, mitochondrial 0.0034 0.0048 0.0086
Loa Loa (eye worm) nuclear receptor nhr-7B 0.003 0.0036 0.0071
Echinococcus multilocularis ATP binding cassette subfamily B (MDR:TAP) 0.0022 0.0013 0.0013
Trypanosoma cruzi tubulin delta chain 0.0594 0.1741 0.3438
Loa Loa (eye worm) hypothetical protein 0.0044 0.0079 0.0157
Trichomonas vaginalis PIKK family atypical protein kinase 0.0056 0.0115 0.0226
Echinococcus granulosus Basic leucine zipper bZIP transcription factor 0.0269 0.0758 0.1196
Entamoeba histolytica phosphofructokinase, putative 0.0113 0.0288 0.0568
Echinococcus multilocularis Peptidase C19, ubiquitin carboxyl terminal hydrolase 2 0.0037 0.006 0.006
Echinococcus multilocularis tubulin epsilon chain 0.0966 0.2864 0.2864
Loa Loa (eye worm) hypothetical protein 0.0094 0.023 0.0454
Loa Loa (eye worm) tubulin alpha 2 0.0869 0.2573 0.5081
Echinococcus granulosus CREB binding protein 0.0033 0.0046 0.0072
Mycobacterium tuberculosis Probable soluble pyridine nucleotide transhydrogenase SthA (STH) (NAD(P)(+) transhydrogenase [B-specific]) (nicotinamide nucleot 0.0034 0.0048 0.0358
Loa Loa (eye worm) hypothetical protein 0.003 0.0036 0.0071
Schistosoma mansoni axis inhibition protein axin 0.0044 0.0079 0.0125

Activities

Activity type Activity value Assay description Source Reference
Potency (functional) = 0.0045 um PUBCHEM_BIOASSAY: qHTS Assay for Enhancers of SMN2 Splice Variant Expression. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) 2.3323 uM PUBCHEM_BIOASSAY: Primary qHTS for delayed death inhibitors of the malarial parasite plastid, 96 hour incubation. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID488745, AID488752, AID488774, AID504848, AID504850] ChEMBL. No reference
Potency (functional) 18.526 uM PUBCHEM_BIOASSAY: Primary qHTS for delayed death inhibitors of the malarial parasite plastid, 48 hour incubation. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID488752, AID488774, AID504848, AID504850] ChEMBL. No reference
Potency (functional) = 28.1838 um PUBCHEM_BIOASSAY: qHTS Assay for Inhibitors of Aldehyde Dehydrogenase 1 (ALDH1A1). (Class of assay: confirmatory) [Related pubchem assays: 1030 (qHTS Validation Assay for Inhibitors of aldehyde dehydrogenase 1 (ALDH1A1))] ChEMBL. No reference
Potency (functional) 29.0929 uM PUBCHEM_BIOASSAY: qHTS screen for small molecules that inhibit ELG1-dependent DNA repair in human embryonic kidney (HEK293T) cells expressing luciferase-tagged ELG1. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID493107, AID493125] ChEMBL. No reference
Potency (functional) = 35.4813 um PUBCHEM_BIOASSAY: qHTS Assay for the Inhibitors of Schistosoma Mansoni Peroxiredoxins. (Class of assay: confirmatory) [Related pubchem assays: 1011 (Confirmation Concentration-Response Assay for Inhibitors of the Schistosoma mansoni Redox Cascade ), 448 (Schistosoma Mansoni Peroxiredoxins (Prx2) and thioredoxin glutathione reductase (TGR) coupled assay)] ChEMBL. No reference
Potency (functional) 47.4436 uM PubChem BioAssay. qHTS for Inhibitors of ATXN expression. (Class of assay: confirmatory) ChEMBL. No reference

Phenotypes

Whole-cell/tissue/organism interactions

Species name Source Reference Is orphan
Plasmodium falciparum ChEMBL23

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

No literature references available for this target.

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