Detailed information for compound 1409917

Basic information

Technical information
  • TDR Targets ID: 1409917
  • Name: N-[(4-propan-2-yloxyphenyl)methyl]chroman-3-c arboxamide
  • MW: 325.402 | Formula: C20H23NO3
  • H donors: 1 H acceptors: 1 LogP: 3.47 Rotable bonds: 6
    Rule of 5 violations (Lipinski): 1
  • SMILES: CC(Oc1ccc(cc1)CNC(=O)C1COc2c(C1)cccc2)C
  • InChi: 1S/C20H23NO3/c1-14(2)24-18-9-7-15(8-10-18)12-21-20(22)17-11-16-5-3-4-6-19(16)23-13-17/h3-10,14,17H,11-13H2,1-2H3,(H,21,22)
  • InChiKey: OMDLNBFEPAWVQP-UHFFFAOYSA-N  


Substructure search Similarity search

Network

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Synonyms

  • N-[(4-isopropoxyphenyl)methyl]chroman-3-carboxamide
  • N-[(4-isopropoxyphenyl)methyl]-3-chromancarboxamide
  • N-(4-isopropoxybenzyl)chroman-3-carboxamide
  • G668-0305
  • NCGC00132607-01

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Brugia malayi Cathepsin L-like precursor 0.0367 0.6533 0.6533
Onchocerca volvulus 0.0544 1 1
Echinococcus multilocularis growth factor receptor bound protein 2 0.0393 0.7039 0.7039
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0544 1 1
Brugia malayi cathepsin Z-like cysteine proteinase 0.0108 0.1449 0.1449
Echinococcus multilocularis tyrosine protein kinase Fgr 0.0034 0.0008 0.0008
Entamoeba histolytica cysteine protease, putative 0.0285 0.4915 0.4054
Brugia malayi Papain family cysteine protease containing protein 0.0285 0.4915 0.4915
Plasmodium vivax unspecified product 0.0177 0.2807 0.1588
Echinococcus multilocularis cathepsin L cysteine protease 0.0544 1 1
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0285 0.4915 0.254
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0544 1 1
Onchocerca volvulus 0.0544 1 1
Echinococcus multilocularis cathepsin l cysteine peptidase 0.0544 1 1
Schistosoma mansoni subfamily C1A unassigned peptidase (C01 family) 0.0108 0.1449 0.1449
Brugia malayi Papain family cysteine protease containing protein 0.0108 0.1449 0.1449
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0544 1 1
Echinococcus granulosus tyrosine protein kinase Fyn 0.0034 0.0008 0.0008
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0108 0.1449 0.1449
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0544 1 1
Entamoeba histolytica cysteine protease, putative 0.0285 0.4915 0.4054
Brugia malayi cathepsin L precursor 0.0108 0.1449 0.1449
Entamoeba histolytica cysteine protease, putative 0.0285 0.4915 0.4054
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0544 1 1
Plasmodium falciparum cysteine proteinase falcipain 2a 0.0544 1 1
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0544 1 1
Echinococcus granulosus cathepsin l1 0.0367 0.6533 0.6533
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0394 0.706 0.706
Echinococcus granulosus cathepsin l cysteine peptidase 0.0544 1 1
Onchocerca volvulus 0.0367 0.6533 0.5946
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.0544 1 1
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0367 0.6533 0.5946
Echinococcus granulosus 3'partial|tyrosine protein kinase Fgr 0.0034 0.0008 0.0008
Onchocerca volvulus 0.0544 1 1
Echinococcus multilocularis tyrosine protein kinase Btk29A 0.0034 0.0008 0.0008
Leishmania major cathepsin L-like protease 0.0544 1 1
Toxoplasma gondii cathepsin CPL 0.0544 1 1
Echinococcus granulosus tyrosine protein kinase Btk29A 0.0034 0.0008 0.0008
Echinococcus granulosus cathepsin L 0.0108 0.1449 0.1449
Loa Loa (eye worm) SRC-1 0.0034 0.0008 0.0008
Giardia lamblia Cathepsin B precursor 0.0196 0.3184 1
Brugia malayi Cathepsin L-like precursor 0.0367 0.6533 0.6533
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0177 0.2807 0.2807
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0544 1 1
Schistosoma mansoni tyrosine kinase 0.0034 0.0008 0.0008
Schistosoma mansoni tyrosine kinase 0.0034 0.0008 0.0008
Loa Loa (eye worm) hypothetical protein 0.0108 0.1449 0.1449
Schistosoma mansoni cathepsin s 0.0177 0.2807 0.2807
Echinococcus multilocularis cathepsin b 0.0394 0.706 0.706
Plasmodium falciparum cysteine proteinase falcipain 1 0.0285 0.4915 0.4054
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0544 1 1
Onchocerca volvulus Cathepsin L homolog 0.0544 1 1
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0196 0.3184 0.2029
Entamoeba histolytica cysteine proteinase, putative 0.0285 0.4915 0.4054
Leishmania major cathepsin L-like protease 0.0544 1 1
Schistosoma mansoni proto-oncogene tyrosine-protein kinase src 0.0034 0.0008 0.0008
Entamoeba histolytica cysteine proteinase, putative 0.0544 1 1
Brugia malayi cathepsin F-like cysteine proteinase 0.0177 0.2807 0.2807
Trypanosoma cruzi cysteine proteinase, putative 0.0285 0.4915 0.4054
Leishmania major cathepsin L-like protease 0.0544 1 1
Plasmodium vivax vivapain-2 0.0544 1 1
Trypanosoma cruzi cysteine peptidase, clan CA, family C1, cathepsin L-like, putative 0.0367 0.6533 0.5946
Loa Loa (eye worm) hypothetical protein 0.0108 0.1449 0.1449
Echinococcus granulosus cathepsin b 0.0394 0.706 0.706
Echinococcus granulosus tyrosine protein kinase Fyn 0.0034 0.0008 0.0008
Entamoeba histolytica cysteine proteinase, putative 0.0285 0.4915 0.4054
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0285 0.4915 0.4054
Echinococcus multilocularis cysteine protease 0.0544 1 1
Loa Loa (eye worm) hypothetical protein 0.0177 0.2807 0.2807
Echinococcus granulosus cathepsin b 0.0394 0.706 0.706
Brugia malayi SRC-1 0.0034 0.0008 0.0008
Loa Loa (eye worm) hypothetical protein 0.0367 0.6533 0.6533
Brugia malayi Sex muscle abnormal protein 5 0.0393 0.7039 0.7039
Loa Loa (eye worm) ctsf protein 0.0544 1 1
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0108 0.1449 0.1449
Entamoeba histolytica cysteine protease, putative 0.0285 0.4915 0.4054
Echinococcus multilocularis cathepsin L 0.0108 0.1449 0.1449
Plasmodium vivax vivapain-3 0.0285 0.4915 0.4054
Echinococcus multilocularis proto oncogene tyrosine protein kinase LCK 0.0034 0.0008 0.0008
Leishmania major cathepsin L-like protease 0.0544 1 1
Echinococcus granulosus proto oncogene tyrosine protein kinase LCK 0.0034 0.0008 0.0008
Brugia malayi Papain family cysteine protease containing protein 0.0108 0.1449 0.1449
Entamoeba histolytica cysteine protease, putative 0.0285 0.4915 0.4054
Trypanosoma cruzi cysteine peptidase, putative 0.0544 1 1
Onchocerca volvulus 0.0544 1 1
Trypanosoma cruzi cysteine proteinase, putative 0.0285 0.4915 0.4054
Echinococcus granulosus cathepsin l1 0.0544 1 1
Echinococcus multilocularis cathepsin L cysteine protease 0.0544 1 1
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0544 1 1
Echinococcus multilocularis cysteine protease 0.0544 1 1
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0544 1 1
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.0544 1 1
Brugia malayi cathepsin Z-like cysteine proteinase 0.0108 0.1449 0.1449
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0544 1 1
Trypanosoma cruzi cysteine peptidase, putative 0.0285 0.4915 0.4054
Plasmodium vivax vivapain-2 0.0544 1 1
Schistosoma mansoni growth factor receptor-bound protein 0.0393 0.7039 0.7039
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0108 0.1449 0.1449
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0108 0.1449 0.1449
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0108 0.1449 0.1449
Loa Loa (eye worm) hypothetical protein 0.0108 0.1449 0.1449
Schistosoma mansoni cathepsin B (C01 family) 0.0108 0.1449 0.1449
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.0285 0.4915 0.4915
Echinococcus granulosus tyrosine protein kinase Lyn 0.0034 0.0008 0.0008
Trypanosoma cruzi cysteine peptidase C (CPC), putative 0.0196 0.3184 0.2029
Leishmania major cathepsin L-like protease 0.0544 1 1
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0108 0.1449 0.1449
Brugia malayi cathepsin L-like cysteine proteinase, identical 0.0177 0.2807 0.2807
Echinococcus multilocularis cathepsin b 0.0394 0.706 0.706
Echinococcus multilocularis c src tyrosine kinase 0.0034 0.0008 0.0008
Entamoeba histolytica cysteine proteinase, putative 0.0285 0.4915 0.4054
Schistosoma mansoni cathepsin C 0.0108 0.1449 0.1449
Loa Loa (eye worm) fibroinase 0.0544 1 1
Entamoeba histolytica cysteine protease, putative 0.0285 0.4915 0.4054
Schistosoma mansoni subfamily C1A unassigned peptidase (C01 family) 0.0108 0.1449 0.1449
Echinococcus granulosus tyrosine protein kinase Src64B 0.0034 0.0008 0.0008
Trypanosoma cruzi cysteine peptidase C (CPC), putative 0.0394 0.706 0.6561
Trypanosoma cruzi cysteine protease, putative 0.0285 0.4915 0.4054
Onchocerca volvulus 0.0544 1 1
Brugia malayi Papain family cysteine protease containing protein 0.0285 0.4915 0.4915
Loa Loa (eye worm) hypothetical protein 0.0177 0.2807 0.2807
Loa Loa (eye worm) hypothetical protein 0.0544 1 1
Brugia malayi cahepsin L-like non-peptiedase homolog 0.0108 0.1449 0.1449
Echinococcus granulosus growth factor receptor bound protein 2 0.0393 0.7039 0.7039
Onchocerca volvulus 0.0544 1 1
Onchocerca volvulus Cathepsin L homolog 0.0544 1 1
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0544 1 1
Schistosoma mansoni tyrosine kinase 0.0034 0.0008 0.0008
Entamoeba histolytica cysteine protease, putative 0.0285 0.4915 0.4054
Loa Loa (eye worm) Papain cysteine protease/cathepsin propeptide inhibitor-containing protein 0.0544 1 1
Giardia lamblia Cathepsin B precursor 0.0196 0.3184 1
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0544 1 1
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0544 1 1
Brugia malayi cathepsin F-like cysteine proteinase 0.0108 0.1449 0.1449
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0544 1 1
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0544 1 1
Echinococcus granulosus c src tyrosine kinase 0.0034 0.0008 0.0008
Entamoeba histolytica cysteine protease, putative 0.0285 0.4915 0.4054
Loa Loa (eye worm) hypothetical protein 0.0108 0.1449 0.1449
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.0285 0.4915 0.4915
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0544 1 1
Trypanosoma cruzi cysteine peptidase, putative 0.0177 0.2807 0.1588
Brugia malayi Papain family cysteine protease containing protein 0.0108 0.1449 0.1449
Echinococcus granulosus cathepsin L cysteine protease 0.0285 0.4915 0.4915
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0544 1 1
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0544 1 1
Onchocerca volvulus 0.0544 1 1
Echinococcus multilocularis tyrosine protein kinase Src64B 0.0034 0.0008 0.0008
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0544 1 1
Entamoeba histolytica cysteine protease, putative 0.0285 0.4915 0.4054
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0544 1 1
Loa Loa (eye worm) hypothetical protein 0.0108 0.1449 0.1449
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0544 1 1
Leishmania major cathepsin L-like protease 0.0544 1 1
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0544 1 1
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0034 0.0008 0.0008
Plasmodium vivax unspecified product 0.0285 0.4915 0.4054
Plasmodium vivax vivapain-1 0.0285 0.4915 0.4054
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0108 0.1449 0.1449
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0544 1 1
Entamoeba histolytica cysteine proteinase, putative 0.0544 1 1
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0196 0.3184 0.3184
Loa Loa (eye worm) hypothetical protein 0.0394 0.706 0.706
Entamoeba histolytica cysteine proteinase 1, putative 0.0285 0.4915 0.4054
Brugia malayi Papain family cysteine protease containing protein 0.0544 1 1
Brugia malayi cathepsin B-like cysteine proteinase 0.0394 0.706 0.706
Brugia malayi Cathepsin L-like precursor 0.0177 0.2807 0.2807
Leishmania major cysteine peptidase A (CPA) 0.0544 1 1
Brugia malayi fibroinase precursor 0.0108 0.1449 0.1449
Brugia malayi Cathepsin L-like precursor 0.0544 1 1
Schistosoma mansoni SmCB2 peptidase (C01 family) 0.0394 0.706 0.706
Plasmodium falciparum cysteine proteinase falcipain 3 0.0544 1 1
Trypanosoma cruzi cysteine peptidase (N-terminal), putative 0.0285 0.4915 0.4054
Brugia malayi Cathepsin L-like precursor 0.0544 1 1
Schistosoma mansoni growth factor receptor-bound protein 0.0393 0.7039 0.7039
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0544 1 1
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0285 0.4915 0.4054
Echinococcus multilocularis cathepsin l cysteine peptidase 0.0544 1 1
Entamoeba histolytica cysteine protease, putative 0.0285 0.4915 0.4054
Echinococcus granulosus tyrosine protein kinase Src42A 0.0034 0.0008 0.0008
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0544 1 1
Onchocerca volvulus Cathepsin F homolog 0.0544 1 1
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0544 1 1
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0367 0.6533 0.5946
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0034 0.0008 0.0008
Loa Loa (eye worm) cysteine protease 0.0544 1 1
Echinococcus granulosus tyrosine protein kinase Fyn 0.0034 0.0008 0.0008
Brugia malayi cathepsin L-like cysteine proteinase 0.0108 0.1449 0.1449
Entamoeba histolytica cysteine proteinase, putative 0.0285 0.4915 0.4054
Echinococcus granulosus cysteine protease 0.0285 0.4915 0.4915
Entamoeba histolytica cysteine protease, putative 0.0544 1 1
Brugia malayi cathepsin L-like precursor 0.0367 0.6533 0.6533
Trypanosoma cruzi cysteine peptidase, putative 0.0544 1 1
Entamoeba histolytica cysteine proteinase 2 0.0285 0.4915 0.4054
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0034 0.0008 0.0008
Echinococcus multilocularis tyrosine protein kinase Abl 0.0034 0.0008 0.0008
Echinococcus granulosus cathepsin L 0.0285 0.4915 0.4915
Schistosoma mansoni dipeptidyl-peptidase I (C01 family) 0.0108 0.1449 0.1449
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0544 1 1
Echinococcus multilocularis tyrosine protein kinase lyn lyn a protein tyrosine kinase lymphocyte specific protein tyrosine kinase 0.0034 0.0008 0.0008
Loa Loa (eye worm) cysteine proteinase cathepsin Z 0.0108 0.1449 0.1449
Echinococcus multilocularis tyrosine protein kinase lyn tyrosine protein kinase blk 0.0034 0.0008 0.0008
Schistosoma mansoni cathepsin S (C01 family) 0.0108 0.1449 0.1449
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0394 0.706 0.706
Schistosoma mansoni cathepsin F (C01 family) 0.0544 1 1
Toxoplasma gondii cathepsin B 0.0196 0.3184 0.2029
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0544 1 1
Brugia malayi Cathepsin L-like cysteine proteinase 0.0367 0.6533 0.6533
Brugia malayi Tyrosine-protein kinase abl-1 0.0034 0.0008 0.0008
Loa Loa (eye worm) hypothetical protein 0.0177 0.2807 0.2807
Schistosoma mansoni cathepsin F (C01 family) 0.0367 0.6533 0.6533
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0285 0.4915 0.254
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0544 1 1
Entamoeba histolytica cysteine proteinase, putative 0.0367 0.6533 0.5946
Brugia malayi Cathepsin L-like precursor 0.0544 1 1
Entamoeba histolytica cysteine protease, putative 0.0285 0.4915 0.4054
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.0285 0.4915 0.4915
Echinococcus granulosus cathepsin L cysteine proteinase 0.0544 1 1
Entamoeba histolytica cysteine protease, putative 0.0285 0.4915 0.4054
Brugia malayi Cathepsin L-like precursor 0.0544 1 1
Loa Loa (eye worm) hypothetical protein 0.0367 0.6533 0.6533
Loa Loa (eye worm) hypothetical protein 0.0108 0.1449 0.1449
Trypanosoma cruzi cysteine peptidase, putative 0.0544 1 1
Trypanosoma cruzi cruzipain precursor, putative 0.0177 0.2807 0.1588
Leishmania major cathepsin L-like protease 0.0544 1 1
Giardia lamblia Cathepsin B precursor 0.0196 0.3184 1
Entamoeba histolytica cysteine protease, putative 0.0285 0.4915 0.4054
Trypanosoma cruzi cruzipain precursor, putative 0.0544 1 1
Echinococcus multilocularis tyrosine protein kinase Src42A 0.0034 0.0008 0.0008
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0394 0.706 0.706
Brugia malayi Cathepsin L-like precursor 0.0544 1 1
Loa Loa (eye worm) sex muscle abnormal protein 5 0.0393 0.7039 0.7039
Leishmania major cathepsin L-like protease 0.0544 1 1
Schistosoma mansoni cathepsin F (C01 family) 0.0544 1 1
Schistosoma mansoni tyrosine kinase 0.0034 0.0008 0.0008
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0544 1 1
Echinococcus multilocularis cathepsin L 0.0285 0.4915 0.4915
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0544 1 1
Trypanosoma cruzi cysteine peptidase, putative 0.0544 1 1
Plasmodium falciparum cysteine proteinase falcipain 2b 0.0544 1 1
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0544 1 1
Schistosoma mansoni subfamily C1A non-peptidase homologue (C01 family) 0.0108 0.1449 0.1449
Loa Loa (eye worm) hypothetical protein 0.0367 0.6533 0.6533
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0544 1 1
Loa Loa (eye worm) cathepsin B 0.0196 0.3184 0.3184
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0544 1 1

Activities

Activity type Activity value Assay description Source Reference
Potency (functional) 50.1187 uM PUBCHEM_BIOASSAY: qHTS for Inhibitors of mutant isocitrate dehydrogenase 1 (IDH1): qHTS. (Class of assay: confirmatory) ChEMBL. No reference

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

Bibliographic References

No literature references available for this target.

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