Detailed information for compound 1412428

Basic information

Technical information
  • TDR Targets ID: 1412428
  • Name: 4-(2,4-dimethylphenyl)-5-(thiophen-2-ylmethyl )-2H-1,2,4-triazole-3-thione
  • MW: 301.43 | Formula: C15H15N3S2
  • H donors: 0 H acceptors: 2 LogP: 3.97 Rotable bonds: 3
    Rule of 5 violations (Lipinski): 1
  • SMILES: Cc1ccc(c(c1)C)n1c(S)nnc1Cc1cccs1
  • InChi: 1S/C15H15N3S2/c1-10-5-6-13(11(2)8-10)18-14(16-17-15(18)19)9-12-4-3-7-20-12/h3-8H,9H2,1-2H3,(H,17,19)
  • InChiKey: AFRSFEXFOGGVHN-UHFFFAOYSA-N  


Substructure search Similarity search

Network

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Synonyms

  • 4-(2,4-dimethylphenyl)-5-(2-thienylmethyl)-2H-1,2,4-triazole-3-thione
  • AJ-292/41695017
  • ZINC00193770
  • STK051257
  • 4-(2,4-dimethylphenyl)-5-(2-thienylmethyl)-4H-1,2,4-triazole-3-thiol
  • MLS000579324
  • SMR000198606

Targets

Known targets for this compound

Species Target name Source Bibliographic reference
Mus musculus RAR-related orphan receptor gamma Starlite/ChEMBL No references
Homo sapiens hydroxyprostaglandin dehydrogenase 15-(NAD) Starlite/ChEMBL No references
Leishmania mexicana pyruvate kinase, putative Starlite/ChEMBL No references
Homo sapiens euchromatic histone-lysine N-methyltransferase 2 Starlite/ChEMBL No references
Trypanosoma brucei hypothetical protein, conserved Starlite/ChEMBL No references

Predicted pathogen targets for this compound

By orthology
Species Potential target Known druggable target/s Ortholog Group
Brugia malayi Pre-SET motif family protein Get druggable targets OG5_131470 All targets in OG5_131470
Mycobacterium ulcerans pyruvate kinase Get druggable targets OG5_126685 All targets in OG5_126685
Leishmania braziliensis pyruvate kinase Get druggable targets OG5_126685 All targets in OG5_126685
Leishmania braziliensis pyruvate kinase Get druggable targets OG5_126685 All targets in OG5_126685
Leishmania donovani pyruvate kinase, putative Get druggable targets OG5_126685 All targets in OG5_126685
Loa Loa (eye worm) pyruvate kinase Get druggable targets OG5_126685 All targets in OG5_126685
Plasmodium knowlesi pyruvate kinase, putative Get druggable targets OG5_126685 All targets in OG5_126685
Trichomonas vaginalis pyruvate kinase, putative Get druggable targets OG5_126685 All targets in OG5_126685
Theileria parva pyruvate kinase, putative Get druggable targets OG5_126685 All targets in OG5_126685
Leishmania donovani HpcH/HpaI aldolase/citrate lyase family, putative Get druggable targets OG5_146801 All targets in OG5_146801
Onchocerca volvulus Pyruvate kinase homolog Get druggable targets OG5_126685 All targets in OG5_126685
Schistosoma japonicum ko:K00873 pyruvate kinase [EC2.7.1.40], putative Get druggable targets OG5_126685 All targets in OG5_126685
Loa Loa (eye worm) pre-SET domain-containing protein family protein Get druggable targets OG5_131470 All targets in OG5_131470
Echinococcus multilocularis pyruvate kinase Get druggable targets OG5_126685 All targets in OG5_126685
Trypanosoma cruzi pyruvate kinase 2, putative Get druggable targets OG5_126685 All targets in OG5_126685
Trichomonas vaginalis pyruvate kinase, putative Get druggable targets OG5_126685 All targets in OG5_126685
Candida albicans pyruvate kinase Get druggable targets OG5_126685 All targets in OG5_126685
Leishmania mexicana pyruvate kinase Get druggable targets OG5_126685 All targets in OG5_126685
Brugia malayi Pyruvate kinase, M2 isozyme Get druggable targets OG5_126685 All targets in OG5_126685
Trypanosoma cruzi hypothetical protein, conserved Get druggable targets OG5_146801 All targets in OG5_146801
Giardia lamblia Pyruvate kinase Get druggable targets OG5_126685 All targets in OG5_126685
Entamoeba histolytica pyruvate kinase, putative Get druggable targets OG5_126685 All targets in OG5_126685
Plasmodium vivax pyruvate kinase, putative Get druggable targets OG5_126685 All targets in OG5_126685
Leishmania major hypothetical protein, conserved Get druggable targets OG5_146801 All targets in OG5_146801
Mycobacterium leprae Probable pyruvate kinase PykA Get druggable targets OG5_126685 All targets in OG5_126685
Echinococcus multilocularis pyruvate kinase Get druggable targets OG5_126685 All targets in OG5_126685
Trypanosoma congolense HpcH/HpaI aldolase/citrate lyase family, putative Get druggable targets OG5_146801 All targets in OG5_146801
Leishmania infantum hypothetical protein, conserved Get druggable targets OG5_146801 All targets in OG5_146801
Leishmania major pyruvate kinase Get druggable targets OG5_126685 All targets in OG5_126685
Loa Loa (eye worm) pyruvate kinase-PB Get druggable targets OG5_126685 All targets in OG5_126685
Leishmania major pyruvate kinase Get druggable targets OG5_126685 All targets in OG5_126685
Plasmodium falciparum pyruvate kinase Get druggable targets OG5_126685 All targets in OG5_126685
Onchocerca volvulus Pyruvate kinase homolog Get druggable targets OG5_126685 All targets in OG5_126685
Leishmania braziliensis hypothetical protein, conserved Get druggable targets OG5_146801 All targets in OG5_146801
Schistosoma mansoni pyruvate kinase Get druggable targets OG5_126685 All targets in OG5_126685
Trypanosoma brucei gambiense pyruvate kinase 1, putative Get druggable targets OG5_126685 All targets in OG5_126685
Echinococcus multilocularis pyruvate kinase Get druggable targets OG5_126685 All targets in OG5_126685
Leishmania mexicana hypothetical protein, conserved Get druggable targets OG5_146801 All targets in OG5_146801
Echinococcus granulosus pyruvate kinase Get druggable targets OG5_126685 All targets in OG5_126685
Leishmania infantum pyruvate kinase Get druggable targets OG5_126685 All targets in OG5_126685
Leishmania braziliensis pyruvate kinase Get druggable targets OG5_126685 All targets in OG5_126685
Trypanosoma brucei gambiense pyruvate kinase 1, putative Get druggable targets OG5_126685 All targets in OG5_126685
Leishmania mexicana pyruvate kinase, putative Get druggable targets OG5_126685 All targets in OG5_126685
Schistosoma mansoni pyruvate kinase Get druggable targets OG5_126685 All targets in OG5_126685
Onchocerca volvulus Get druggable targets OG5_131470 All targets in OG5_131470
Cryptosporidium hominis pyruvate kinase Get druggable targets OG5_126685 All targets in OG5_126685
Trypanosoma brucei pyruvate kinase 1, putative Get druggable targets OG5_126685 All targets in OG5_126685
Loa Loa (eye worm) pyruvate kinase Get druggable targets OG5_126685 All targets in OG5_126685
Trypanosoma brucei hypothetical protein, conserved Get druggable targets OG5_146801 All targets in OG5_146801
Neospora caninum Pyruvate kinase (EC 2.7.1.40), related Get druggable targets OG5_126685 All targets in OG5_126685
Trypanosoma cruzi pyruvate kinase 2, putative Get druggable targets OG5_126685 All targets in OG5_126685
Echinococcus granulosus pyruvate kinase Get druggable targets OG5_126685 All targets in OG5_126685
Plasmodium yoelii pyruvate kinase Get druggable targets OG5_126685 All targets in OG5_126685
Trypanosoma congolense pyruvate kinase 1, putative Get druggable targets OG5_126685 All targets in OG5_126685
Loa Loa (eye worm) pyruvate kinase Get druggable targets OG5_126685 All targets in OG5_126685
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_126685 All targets in OG5_126685
Leishmania infantum pyruvate kinase Get druggable targets OG5_126685 All targets in OG5_126685
Schistosoma japonicum Pyruvate kinase isozyme R, putative Get druggable targets OG5_126685 All targets in OG5_126685
Chlamydia trachomatis pyruvate kinase Get druggable targets OG5_126685 All targets in OG5_126685
Trichomonas vaginalis set domain proteins, putative Get druggable targets OG5_131470 All targets in OG5_131470
Trypanosoma brucei gambiense hypothetical protein, conserved Get druggable targets OG5_146801 All targets in OG5_146801
Babesia bovis pyruvate kinase, putative Get druggable targets OG5_126685 All targets in OG5_126685
Plasmodium berghei pyruvate kinase, putative Get druggable targets OG5_126685 All targets in OG5_126685
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_126685 All targets in OG5_126685
Candida albicans pyruvate kinase Get druggable targets OG5_126685 All targets in OG5_126685
Onchocerca volvulus Pyruvate kinase homolog Get druggable targets OG5_126685 All targets in OG5_126685
Trypanosoma cruzi hypothetical protein, conserved Get druggable targets OG5_146801 All targets in OG5_146801
Trypanosoma brucei pyruvate kinase 1 Get druggable targets OG5_126685 All targets in OG5_126685
Brugia malayi Pyruvate kinase, muscle isozyme Get druggable targets OG5_126685 All targets in OG5_126685
Mycobacterium tuberculosis Probable pyruvate kinase PykA Get druggable targets OG5_126685 All targets in OG5_126685
Toxoplasma gondii pyruvate kinase PyK1 Get druggable targets OG5_126685 All targets in OG5_126685
Cryptosporidium parvum pyruvate kinase Get druggable targets OG5_126685 All targets in OG5_126685
By sequence similarity to non orthologous known druggable targets
Species Potential target Known druggable target Length Alignment span Identity
Plasmodium falciparum steroid dehydrogenase, putative hydroxyprostaglandin dehydrogenase 15-(NAD) 266 aa 216 aa 22.2 %
Echinococcus granulosus pyruvate kinase pyruvate kinase, putative 498 aa 515 aa 27.6 %
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Brugia malayi Intermediate filament tail domain containing protein 0.017 0.0753 0.1107
Entamoeba histolytica estradiol 17-beta-dehydrogenase, putative 0.0021 0.0013 0.0081
Loa Loa (eye worm) hypothetical protein 0.0123 0.0518 0.0623
Trypanosoma cruzi hypothetical protein, conserved 0.0257 0.1183 1
Schistosoma mansoni carbonyl reductase 0.0021 0.0013 0.0013
Loa Loa (eye worm) hypothetical protein 0.0019 0.0006 0.0005
Trichomonas vaginalis sugar transporter, putative 0.0019 0.0006 0.0029
Brugia malayi TATA binding protein associated factor 0.0138 0.0594 0.0873
Echinococcus multilocularis neuroligin 0.0023 0.0023 0.0021
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0019 0.0004 0.0002
Plasmodium falciparum pyruvate kinase 0.004 0.011 0.182
Echinococcus multilocularis methyl CpG binding domain protein 2 0.002 0.001 0.0008
Echinococcus granulosus acetylcholinesterase 0.0134 0.0575 0.0573
Echinococcus multilocularis snurportin 1 0.0305 0.142 0.1418
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0021 0.0013 0.0029
Echinococcus multilocularis puromycin sensitive aminopeptidase 0.0094 0.0376 0.0374
Giardia lamblia Pyrophosphate-fructose 6-phosphate 1-phosphotransferase alpha subunit 0.0035 0.0082 0.3942
Schistosoma mansoni steroid dehydrogenase 0.0021 0.0013 0.0013
Trypanosoma brucei cytochrome P450, putative 0.0069 0.0255 0.2152
Brugia malayi steroid hormone receptor 0.026 0.1198 0.1763
Trichomonas vaginalis adenylate cyclase, putative 0.0067 0.0244 0.1815
Mycobacterium tuberculosis POSSIBLE PARA-NITROBENZYL ESTERASE (FRAGMENT) 0.0023 0.0023 0.0052
Brugia malayi Death domain containing protein 0.0028 0.0051 0.0072
Loa Loa (eye worm) protein-tyrosine phosphatase 0.0379 0.1788 0.2157
Entamoeba histolytica hypothetical protein 0.0298 0.1387 1
Loa Loa (eye worm) hypothetical protein 0.0023 0.0023 0.0025
Trichomonas vaginalis glutamine synthetase, putative 0.0034 0.0079 0.0578
Schistosoma mansoni thyroid hormone receptor 0.026 0.1198 0.1198
Loa Loa (eye worm) hypothetical protein 0.0123 0.0518 0.0623
Trichomonas vaginalis PIKK family atypical protein kinase 0.0035 0.0085 0.0621
Trypanosoma brucei glucose transporter, putative 0.0019 0.0006 0.0051
Echinococcus granulosus solute carrier family 2 facilitated glucose 0.0019 0.0006 0.0004
Echinococcus multilocularis 6 phosphofructokinase 0.0129 0.0547 0.0545
Trichomonas vaginalis phosphofructokinase, putative 0.0035 0.0082 0.0602
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative 0.0019 0.0002 0.0019
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0123 0.0518 0.0516
Mycobacterium ulcerans cytochrome P450 187A5 Cyp187A5 0.0033 0.0074 0.0181
Echinococcus granulosus leukotriene A 4 hydrolase 0.169 0.8279 0.8279
Brugia malayi Hypothetical tyrosinase-like protein C02C2.1 in chromosome III 0.009 0.0355 0.0521
Brugia malayi Carboxylesterase family protein 0.0023 0.0023 0.003
Schistosoma mansoni ankyrin 23/unc44 0.0028 0.0051 0.0051
Echinococcus multilocularis FKBP12 rapamycin complex associated protein 0.0044 0.013 0.0128
Echinococcus granulosus intermediate filament protein 0.017 0.0753 0.0751
Schistosoma mansoni hypothetical protein 0.0213 0.0963 0.0963
Trichomonas vaginalis sugar transport protein, putative 0.0019 0.0006 0.0029
Echinococcus granulosus puromycin sensitive aminopeptidase 0.0232 0.1059 0.1057
Trypanosoma cruzi Aminopeptidase M1, putative 0.0232 0.1059 0.8957
Loa Loa (eye worm) phosphofructokinase 0.0129 0.0547 0.0658
Mycobacterium tuberculosis Probable citrate (pro-3S)-lyase (beta subunit) CitE (citrase) (citratase) (citritase) (citridesmolase) (citrase aldolase) 0.003 0.0057 0.0139
Leishmania major GTP-binding protein, putative 0.0021 0.0014 0.0122
Schistosoma mansoni methyl-cpg binding protein mbd 0.002 0.001 0.001
Schistosoma mansoni single-minded 0.0259 0.1193 0.1193
Mycobacterium ulcerans fusion protein of transposase for IS2606 and sialic acid-transport integral membrane protein NanT 0.002 0.0007 0.0012
Trichomonas vaginalis sugar transporter, putative 0.0019 0.0006 0.0029
Leishmania major cytochrome p450-like protein 0.0033 0.0074 0.0623
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.026 0.1198 0.1196
Schistosoma mansoni BC026374 protein (S09 family) 0.0023 0.0023 0.0023
Echinococcus granulosus endothelin converting enzyme 1 0.0815 0.3945 0.3943
Echinococcus granulosus para nitrobenzyl esterase 0.0023 0.0023 0.0021
Entamoeba histolytica phosphatidylinositol3-kinaseTor2, putative 0.0044 0.013 0.0921
Loa Loa (eye worm) nuclear receptor nhr-7B 0.0123 0.0518 0.0623
Mycobacterium leprae PROBABLE NADH DEHYDROGENASE NDH 0.0086 0.0337 0.0823
Leishmania major DNA topoisomerase ii 0.0056 0.0188 0.159
Trypanosoma cruzi hypothetical protein, conserved 0.0021 0.0013 0.0114
Trypanosoma brucei THT1 - hexose transporter, putative 0.0019 0.0006 0.0051
Loa Loa (eye worm) hypothetical protein 0.0021 0.0013 0.0014
Echinococcus multilocularis pyruvate kinase 0.004 0.011 0.0108
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0021 0.0013 0.0017
Trypanosoma cruzi puromycin-sensitive aminopeptidase-like protein, putative 0.0138 0.0594 0.5022
Trichomonas vaginalis NADPH fad oxidoreductase, putative 0.0023 0.0024 0.0166
Trypanosoma cruzi STE/STE11 serine/threonine-protein kinase, putative 0.0068 0.0246 0.2081
Entamoeba histolytica hypothetical protein 0.0021 0.0013 0.0081
Echinococcus granulosus puromycin sensitive aminopeptidase 0.0232 0.1059 0.1057
Trypanosoma cruzi hypothetical protein, conserved 0.0021 0.0013 0.0114
Schistosoma mansoni short chain dehydrogenase 0.0021 0.0013 0.0013
Toxoplasma gondii phosphofructokinase domain-containing protein 0.0035 0.0082 0.0203
Loa Loa (eye worm) cytochrome P450 family protein 0.0113 0.0468 0.0562
Schistosoma mansoni gliotactin 0.0023 0.0023 0.0023
Trichomonas vaginalis sugar transporter, putative 0.0019 0.0006 0.0029
Schistosoma mansoni steroid dehydrogenase 0.0021 0.0013 0.0013
Onchocerca volvulus 0.0095 0.0382 0.1365
Mycobacterium ulcerans acyl-CoA synthetase 0.0027 0.0046 0.0111
Echinococcus multilocularis solute carrier family 22 0.0019 0.0006 0.0004
Schistosoma mansoni tyrosinase precursor 0.009 0.0355 0.0355
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0021 0.0013 0.0017
Mycobacterium ulcerans cytochrome P450 187A4 Cyp187A4 0.0033 0.0074 0.0181
Trichomonas vaginalis D-aminoacylase, putative 0.0042 0.0117 0.0859
Loa Loa (eye worm) hypothetical protein 0.002 0.0012 0.0012
Trichomonas vaginalis phosphofructokinase, putative 0.0035 0.0082 0.0602
Loa Loa (eye worm) hypothetical protein 0.0042 0.0117 0.0138
Onchocerca volvulus 0.0057 0.0193 0.0684
Echinococcus multilocularis aryl hydrocarbon receptor 0.0067 0.0244 0.0242
Trichomonas vaginalis sugar transporter, putative 0.0019 0.0006 0.0029
Echinococcus granulosus WW domain containing oxidoreductase 0.0021 0.0013 0.0011
Mycobacterium ulcerans acyl-CoA synthetase 0.0027 0.0046 0.0111
Schistosoma mansoni hypothetical protein 0.0213 0.0963 0.0963
Schistosoma mansoni aldehyde dehydrogenase 0.0194 0.087 0.087
Schistosoma mansoni hypothetical protein 0.0071 0.0264 0.0264
Leishmania major hypothetical protein, conserved 0.0021 0.0013 0.0114
Trypanosoma brucei hypothetical protein, conserved 0.0042 0.0117 0.0986
Mycobacterium tuberculosis Possible short-chain dehydrogenase EphD 0.0021 0.0013 0.0029
Trichomonas vaginalis CMGC family protein kinase 0.005 0.0159 0.1179
Echinococcus multilocularis retinol dehydrogenase 11 0.0021 0.0013 0.0011
Brugia malayi hypothetical protein 0.0123 0.0518 0.076
Toxoplasma gondii sugar transporter ST1 0.0019 0.0006 0.001
Trichomonas vaginalis conserved hypothetical protein 0.0019 0.0006 0.0029
Trypanosoma brucei beta-ketoacyl-ACP reductase 2 0.0021 0.0013 0.0114
Echinococcus granulosus mitogen activated protein kinase 3 0.005 0.0159 0.0157
Mycobacterium ulcerans short chain dehydrogenase 0.0021 0.0013 0.0029
Onchocerca volvulus 0.0021 0.0013 0.0037
Toxoplasma gondii ATPase/histidine kinase/DNA gyrase B/HSP90 domain-containing protein 0.0021 0.0012 0.0025
Brugia malayi hypothetical protein 0.0137 0.059 0.0868
Mycobacterium tuberculosis Probable cytochrome P450 140 Cyp140 0.0033 0.0074 0.0181
Loa Loa (eye worm) hypothetical protein 0.0071 0.0262 0.0314
Trichomonas vaginalis sugar transporter, putative 0.0019 0.0006 0.0029
Brugia malayi Common central domain of tyrosinase family protein 0.009 0.0355 0.0521
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0053 0.0172 0.0169
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD5 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0019 0.0006 0.001
Trypanosoma cruzi mitochondrial DNA topoisomerase II, putative 0.0049 0.0153 0.1295
Mycobacterium ulcerans cytochrome P450 188A3 Cyp188A3 0.0033 0.0074 0.0181
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0019 0.0004 0.0002
Mycobacterium ulcerans acyl-CoA synthetase 0.0027 0.0046 0.0111
Trypanosoma cruzi NAD(P)-dependent oxidoreductase, putative 0.0021 0.0013 0.0114
Brugia malayi beta-lactamase family protein 0.0042 0.0117 0.0169
Toxoplasma gondii HEAT repeat-containing protein 0.0029 0.0052 0.0126
Mycobacterium leprae conserved hypothetical protein 0.0042 0.0117 0.0262
Trichomonas vaginalis PIKK family atypical protein kinase 0.0035 0.0085 0.0621
Loa Loa (eye worm) hypothetical protein 0.0027 0.0046 0.0053
Echinococcus granulosus NADP dependent isocitrate dehydrogenase 0.0053 0.0172 0.0169
Loa Loa (eye worm) hypothetical protein 0.0137 0.059 0.0711
Brugia malayi Carboxylesterase family protein 0.0134 0.0575 0.0845
Brugia malayi hypothetical protein 0.0138 0.0594 0.0873
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0023 0.0025 0.0172
Brugia malayi Nuclear hormone receptor-like 1 0.0137 0.059 0.0868
Echinococcus granulosus Aryl hydrocarbon receptor nuclear 0.0067 0.0244 0.0242
Onchocerca volvulus 0.0023 0.0023 0.007
Mycobacterium tuberculosis Probable short-chain type dehydrogenase/reductase 0.0021 0.0013 0.0029
Mycobacterium tuberculosis Probable glutamine synthetase GlnA3 (glutamine synthase) (GS-I) 0.0034 0.0079 0.0195
Chlamydia trachomatis fructose-6-phosphate phosphotransferase 0.0035 0.0082 0.2871
Trypanosoma cruzi aminopeptidase, putative 0.0138 0.0594 0.5022
Brugia malayi nuclear hormone receptor family member nhr-6 0.0123 0.0518 0.076
Trichomonas vaginalis PIKK family atypical protein kinase 0.0033 0.0074 0.0536
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD35 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0019 0.0006 0.001
Entamoeba histolytica short chain dehydrogenase family protein 0.0021 0.0013 0.0081
Entamoeba histolytica short chain dehydrogenase family protein 0.0021 0.0013 0.0081
Trypanosoma cruzi hexose transporter, putative 0.0019 0.0006 0.0051
Mycobacterium tuberculosis Probable oxidoreductase 0.0021 0.0013 0.0029
Trypanosoma cruzi STE group serine/threonine-protein kinase, putative 0.0068 0.0246 0.2081
Trypanosoma brucei glucose transporter, putative 0.0019 0.0006 0.0051
Loa Loa (eye worm) hypothetical protein 0.0019 0.0006 0.0005
Schistosoma mansoni nuclear hormone receptor 0.026 0.1198 0.1198
Schistosoma mansoni aminopeptidase A (M01 family) 0.0138 0.0594 0.0594
Trypanosoma cruzi 3-ketoacyl-CoA reductase, putative 0.0021 0.0013 0.0114
Mycobacterium tuberculosis Probable hydrolase 0.0042 0.0117 0.029
Mycobacterium tuberculosis Carboxylesterase LipT 0.0023 0.0023 0.0052
Trichomonas vaginalis PIKK family atypical protein kinase 0.0035 0.0085 0.0621
Wolbachia endosymbiont of Brugia malayi DNA gyrase, topoisomerase II, B subunit, GyrB 0.0021 0.0012 0.1272
Trypanosoma cruzi p450 reductase, putative 0.0026 0.0039 0.0329
Trichomonas vaginalis PIKK family atypical protein kinase 0.0029 0.0053 0.038
Echinococcus multilocularis GA binding protein alpha chain 0.0072 0.0266 0.0263
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0021 0.0013 0.0017
Entamoeba histolytica glutamine synthetase, putative 0.0034 0.0079 0.0555
Echinococcus granulosus agrin 0.0019 0.0003 0.0001
Mycobacterium tuberculosis Probable cytochrome P450 144 Cyp144 0.0033 0.0074 0.0181
Mycobacterium ulcerans short chain dehydrogenase 0.0021 0.0013 0.0029
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.026 0.1198 0.1763
Mycobacterium tuberculosis Probable short-chain type dehydrogenase/reductase 0.0021 0.0013 0.0029
Loa Loa (eye worm) hypothetical protein 0.0026 0.0039 0.0044
Brugia malayi DNA gyrase/topoisomerase IV, A subunit family protein 0.0062 0.0219 0.032
Echinococcus granulosus family S9 non peptidase ue S09 family 0.0023 0.0023 0.0021
Loa Loa (eye worm) carboxylesterase 0.0134 0.0575 0.0692
Mycobacterium leprae Probable pyruvate kinase PykA 0.004 0.011 0.0245
Trypanosoma brucei THT1 - hexose transporter, putative 0.0019 0.0006 0.0051
Trypanosoma cruzi hexose transporter 0.0019 0.0006 0.0051
Trichomonas vaginalis sugar transporter, putative 0.0019 0.0006 0.0029
Brugia malayi Nuclear hormone receptor family member nhr-25 0.026 0.1198 0.1763
Loa Loa (eye worm) GTP-binding nuclear protein RAN/TC4 0.0021 0.0014 0.0015
Onchocerca volvulus 0.0027 0.0047 0.0156
Leishmania major trypanothione reductase 0.0038 0.0097 0.0824
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.0042 0.0121 0.0119
Schistosoma mansoni nuclear receptor 0.0123 0.0518 0.0518
Echinococcus granulosus slit 2 protein 0.0071 0.0262 0.026
Brugia malayi sodium-independent organic anion transporter family protein 0.0027 0.0047 0.0065
Trichomonas vaginalis glutamine synthetase-bacteria, putative 0.0034 0.0079 0.0578
Mycobacterium ulcerans short chain dehydrogenase 0.0021 0.0013 0.0029
Schistosoma mansoni NADP-specific isocitrate dehydrogenase 0.0053 0.0172 0.0172
Loa Loa (eye worm) hypothetical protein 0.0027 0.0047 0.0054
Echinococcus granulosus cytoplasmic intermediate filament protein 0.0082 0.0317 0.0315
Trichomonas vaginalis short-chain dehydrogenase, putative 0.0021 0.0013 0.0085
Onchocerca volvulus 0.009 0.0355 0.1268
Schistosoma mansoni endothelin-converting enzyme-related 0.0198 0.0893 0.0893
Leishmania major quinonoid dihydropteridine reductase 0.0021 0.0013 0.0114
Brugia malayi prostaglandin transporter 0.0027 0.0047 0.0065
Leishmania major target of rapamycin kinase (TOR) kinase 3 0.0035 0.0085 0.072
Loa Loa (eye worm) glutathione reductase 0.0038 0.0097 0.0115
Echinococcus granulosus nuclear receptor nhr 48 0.0123 0.0518 0.0516
Loa Loa (eye worm) ShTK domain-containing protein 0.009 0.0355 0.0427
Trypanosoma brucei Aminopeptidase M1, putative 0.0232 0.1059 0.8957
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0021 0.0013 0.0017
Onchocerca volvulus 0.0404 0.1909 0.6864
Mycobacterium ulcerans short-chain dehydrogenase 0.0021 0.0013 0.0029
Onchocerca volvulus DNA topoisomerase 2 homolog 0.0045 0.0134 0.0472
Onchocerca volvulus Putative organic anion transporter 0.0027 0.0047 0.0156
Trypanosoma cruzi cytochrome P450 reductase, putative 0.0026 0.0039 0.0329
Brugia malayi Pyruvate kinase, M2 isozyme 0.004 0.011 0.0159
Echinococcus granulosus importin subunit beta 1 0.0029 0.0052 0.005
Mycobacterium ulcerans short chain dehydrogenase 0.0021 0.0013 0.0029
Brugia malayi DNA topoisomerase II, alpha isozyme 0.0062 0.0219 0.032
Schistosoma mansoni gcn5proteinral control of amino-acid synthesis 5-like 2 gcnl2 0.0174 0.0773 0.0773
Trypanosoma cruzi STE group serine/threonine-protein kinase, putative 0.0068 0.0246 0.2081
Schistosoma mansoni organic anion transporter 0.0027 0.0047 0.0047
Plasmodium vivax flavodoxin domain containing protein 0.0023 0.0024 0.0373
Schistosoma mansoni family S9 non-peptidase homologue (S09 family) 0.0023 0.0023 0.0023
Echinococcus multilocularis 3 hydroxyacyl coenzyme A dehydrogenase type 2 0.0245 0.1122 0.112
Brugia malayi tailless protein 0.0123 0.0518 0.076
Trypanosoma cruzi cytochrome P450, putative 0.0069 0.0255 0.2152
Loa Loa (eye worm) hypothetical protein 0.0137 0.059 0.0711
Mycobacterium ulcerans short-chain membrane-associated dehydrogenase 0.0021 0.0013 0.0029
Trypanosoma brucei glucose transporter, putative 0.0019 0.0006 0.0051
Loa Loa (eye worm) isocitrate dehydrogenase 0.0053 0.0172 0.0205
Toxoplasma gondii ABC1 family protein 0.0042 0.0117 0.029
Trichomonas vaginalis adenylate and guanylate cyclases, putative 0.0067 0.0244 0.1815
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.026 0.1198 0.1196
Schistosoma mansoni zinc finger protein 0.0123 0.0518 0.0518
Schistosoma mansoni steroid dehydrogenase 0.0021 0.0013 0.0013
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.026 0.1198 0.4302
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0035 0.0082 0.008
Entamoeba histolytica hypothetical protein 0.0298 0.1387 1
Plasmodium vivax pyruvate kinase, putative 0.004 0.011 0.182
Toxoplasma gondii Kazal-type serine protease inhibitor domain-containing protein 0.0019 0.0003 0.0003
Trichomonas vaginalis PIKK family atypical protein kinase 0.0035 0.0085 0.0621
Mycobacterium leprae PROBABLE GLUTAMINE SYNTHETASE GLNA2 (GLUTAMINE SYNTHASE) (GS-II) 0.0087 0.034 0.0832
Trichomonas vaginalis esterase, putative 0.0042 0.0117 0.0859
Loa Loa (eye worm) hypothetical protein 0.0021 0.0013 0.0014
Echinococcus granulosus subfamily M12B unassigned peptidase 0.0022 0.0018 0.0016
Trypanosoma cruzi Lanosterol 14-alpha demethylase 0.0033 0.0074 0.0623
Trichomonas vaginalis PIKK family atypical protein kinase 0.0026 0.0042 0.0295
Toxoplasma gondii pyruvate kinase PyKII 0.0021 0.0013 0.0027
Onchocerca volvulus 0.0019 0.0006 0.001
Schistosoma mansoni cpg binding protein 0.0063 0.0221 0.0221
Echinococcus multilocularis acetylcholinesterase 0.0134 0.0575 0.0573
Mycobacterium tuberculosis Probable cytochrome P450 137 Cyp137 0.0033 0.0074 0.0181
Schistosoma mansoni steroid dehydrogenase 0.0021 0.0013 0.0013
Onchocerca volvulus 0.0579 0.278 1
Trichomonas vaginalis PIKK family atypical protein kinase 0.0024 0.0029 0.02
Schistosoma mansoni lamin 0.017 0.0753 0.0753
Mycobacterium ulcerans short chain dehydrogenase 0.0021 0.0013 0.0029
Trypanosoma cruzi short chain dehydrogenase/reductase, putative 0.0021 0.0013 0.0114
Trypanosoma brucei glucose transporter, putative 0.0019 0.0006 0.0051
Brugia malayi bHLH-PAS transcription factor 0.0192 0.086 0.1265
Mycobacterium tuberculosis Probable membrane NADH dehydrogenase NdhA 0.0086 0.0337 0.085
Loa Loa (eye worm) oxidoreductase 0.0021 0.0013 0.0014
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD7 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0027 0.0046 0.0083
Loa Loa (eye worm) hypothetical protein 0.0023 0.0023 0.0025
Brugia malayi glutamine synthetase 0.0048 0.0149 0.0216
Loa Loa (eye worm) hypothetical protein 0.0019 0.0006 0.0005
Brugia malayi cytochrome P450 0.0033 0.0074 0.0105
Plasmodium falciparum acyl-CoA synthetase 0.002 0.0012 0.0163
Echinococcus granulosus citrate lyase subunit beta protein 0.003 0.0057 0.0055
Loa Loa (eye worm) hypothetical protein 0.0094 0.0376 0.0451
Loa Loa (eye worm) nuclear receptor NHR-67 0.0123 0.0518 0.0623
Brugia malayi intermediate filament protein 0.017 0.0753 0.1107
Mycobacterium tuberculosis Probable conserved lipoprotein 0.0042 0.0117 0.029
Echinococcus granulosus pyruvate kinase 0.004 0.011 0.0108
Schistosoma mansoni family M13 unassigned peptidase (M13 family) 0.0198 0.0893 0.0893
Leishmania major quinonoid dihydropteridine reductase 0.0021 0.0013 0.0114
Trypanosoma cruzi beta-ketoacyl-ACP reductase 2, putative 0.0021 0.0013 0.0114
Onchocerca volvulus 0.0019 0.0006 0.001
Mycobacterium tuberculosis Probable cytochrome P450 130 Cyp130 0.0033 0.0074 0.0181
Mycobacterium ulcerans cytochrome P450 150A6 Cyp150A6 0.0033 0.0074 0.0181
Leishmania major aminopeptidase, putative,metallo-peptidase, Clan MA(E), Family M1 0.0232 0.1059 0.8957
Echinococcus granulosus aryl hydrocarbon receptor 0.0067 0.0244 0.0242
Leishmania major mitogen activated protein kinase 4, putative;with=GeneDB:LmxM19.1440 0.005 0.0159 0.1346
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.026 0.1198 0.1444
Loa Loa (eye worm) hypothetical protein 0.0019 0.0006 0.0005
Brugia malayi hypothetical protein 0.003 0.0058 0.0082
Loa Loa (eye worm) hypothetical protein 0.002 0.0012 0.0012
Loa Loa (eye worm) hypothetical protein 0.0441 0.2096 0.253
Brugia malayi follicle stimulating hormone receptor 0.0468 0.2226 0.3279
Schistosoma mansoni coup transcription factor 0.026 0.1198 0.1198
Loa Loa (eye worm) hypothetical protein 0.0616 0.2962 0.3576
Wolbachia endosymbiont of Brugia malayi Short-chain alcohol dehydrogenase family enzyme 0.0021 0.0013 0.1465
Brugia malayi ecdysone receptor 0.0123 0.0518 0.076
Trichomonas vaginalis phosphofructokinase, putative 0.0035 0.0082 0.0602
Loa Loa (eye worm) hypothetical protein 0.0815 0.3945 0.4763
Giardia lamblia Kinase, CMGC MAPK 0.005 0.0159 0.772
Loa Loa (eye worm) hypothetical protein 0.0021 0.0013 0.0014
Schistosoma mansoni retinoid-x-receptor (RXR) 0.026 0.1198 0.1198
Mycobacterium ulcerans formate dehydrogenase H FdhF 0.0026 0.0039 0.0093
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.0042 0.0117 0.029
Echinococcus granulosus FKBP12 rapamycin complex associated protein 0.0044 0.013 0.0128
Loa Loa (eye worm) hypothetical protein 0.0057 0.0195 0.0233
Mycobacterium ulcerans hypothetical protein 0.003 0.0057 0.0139
Brugia malayi major facilitator superfamily protein 0.0019 0.0006 0.0006
Leishmania major importin beta-1 subunit, putative 0.0023 0.0025 0.0212
Toxoplasma gondii peptidase family M13 protein 0.0815 0.3945 1
Schistosoma mansoni hypothetical protein 0.0033 0.0074 0.0074
Loa Loa (eye worm) hypothetical protein 0.0042 0.0117 0.0138
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0021 0.0013 0.0017
Loa Loa (eye worm) hypoxia-induced factor 1 0.0802 0.3881 0.4686
Trypanosoma cruzi glutamine synthetase, putative 0.0135 0.0579 0.4895
Mycobacterium ulcerans cytochrome P450 105Q4 Cyp105Q4 0.0033 0.0074 0.0181
Brugia malayi hypothetical protein 0.0232 0.1059 0.1559
Leishmania major 4-coumarate:coa ligase-like protein 0.0027 0.0046 0.039
Echinococcus granulosus glutamine synthetase 0.0135 0.0579 0.0577
Mycobacterium tuberculosis Probable lipase LipD 0.0042 0.0117 0.029
Brugia malayi SPARC precursor 0.0019 0.0003 0.0002
Mycobacterium ulcerans short chain dehydrogenase 0.0021 0.0013 0.0029
Mycobacterium leprae putative cytochrome p450 0.0033 0.0074 0.0153
Loa Loa (eye worm) hypothetical protein 0.026 0.1198 0.1444
Entamoeba histolytica estradiol 17-beta-dehydrogenase, putative 0.0021 0.0013 0.0081
Schistosoma mansoni hypothetical protein 0.0733 0.3538 0.3538
Mycobacterium tuberculosis Probable short chain alcohol dehydrogenase/reductase 0.0021 0.0013 0.0029
Schistosoma mansoni hypothetical protein 0.0213 0.0963 0.0963
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.026 0.1198 0.1196
Mycobacterium tuberculosis Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras 0.0096 0.0385 0.097
Leishmania major myo-inositol/proton symporter (MIT) 0.0019 0.0006 0.0051
Plasmodium falciparum DNA gyrase subunit B 0.0021 0.0012 0.0165
Schistosoma mansoni sugar transporter 0.0019 0.0006 0.0006
Schistosoma mansoni ets-related 0.0218 0.0989 0.0989
Trypanosoma cruzi DNA topoisomerase II, putative 0.0056 0.0188 0.159
Brugia malayi hypothetical protein 0.0298 0.1387 0.2043
Onchocerca volvulus 0.0019 0.0006 0.001
Schistosoma mansoni short chain dehydrogenase 0.0021 0.0013 0.0013
Loa Loa (eye worm) hypothetical protein 0.0123 0.0518 0.0623
Leishmania major glutamine synthetase, putative 0.0135 0.0579 0.4895
Mycobacterium tuberculosis Probable cytochrome P450 125 Cyp125 0.0033 0.0074 0.0181
Loa Loa (eye worm) hypothetical protein 0.026 0.1198 0.1444
Leishmania major apurinic/apyrimidinic endonuclease-redox protein 0.0019 0.0002 0.0019
Trypanosoma brucei NADPH-dependent diflavin oxidoreductase 1 0.0026 0.0039 0.0329
Loa Loa (eye worm) hypothetical protein 0.0815 0.3945 0.4763
Entamoeba histolytica Ran family GTPase 0.0021 0.0014 0.0088
Schistosoma mansoni carbonyl reductase 0.0021 0.0013 0.0013
Schistosoma mansoni pyruvate kinase 0.004 0.011 0.011
Loa Loa (eye worm) oxidoreductase 0.0021 0.0013 0.0014
Giardia lamblia Hypothetical protein 0.0023 0.0024 0.1086
Trichomonas vaginalis Clan MA, family M1, aminopeptidase N-like metallopeptidase 0.0138 0.0594 0.4446
Brugia malayi Kazal-type serine protease inhibitor domain containing protein 0.0019 0.0003 0.0002
Brugia malayi Hypothetical tyrosinase-like protein C02C2.1 in chromosome III 0.009 0.0355 0.0521
Schistosoma mansoni cytochrome P450 reductase 0.0026 0.0039 0.0039
Leishmania major short chain dehydrogenase, putative 0.0021 0.0013 0.0114
Brugia malayi Nuclear hormone receptor family member nhr-3 0.026 0.1198 0.1763
Loa Loa (eye worm) hypothetical protein 0.0027 0.0046 0.0053
Loa Loa (eye worm) sugar transporter 0.0019 0.0006 0.0005
Trichomonas vaginalis PIKK family atypical protein kinase 0.0035 0.0085 0.0621
Echinococcus granulosus dnaJ subfamily B 0.0408 0.1933 0.1931
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0021 0.0013 0.0029
Trypanosoma brucei Lanosterol 14-alpha demethylase 0.0033 0.0074 0.0623
Mycobacterium tuberculosis Probable cytochrome P450 136 Cyp136 0.0033 0.0074 0.0181
Brugia malayi Uncoordinated protein 44 0.0028 0.0051 0.0072
Plasmodium falciparum histone acetyltransferase GCN5 0.0046 0.0139 0.2315
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0048 0.0149 0.0147
Mycobacterium ulcerans short chain dehydrogenase 0.0021 0.0013 0.0029
Schistosoma mansoni aminopeptidase PILS (M01 family) 0.0232 0.1059 0.1059
Brugia malayi Nuclear hormone receptor family member nhr-19 0.026 0.1198 0.1763
Onchocerca volvulus Dehydrogenase\/reductase SDR family member 13 homolog 0.0021 0.0013 0.0037
Schistosoma mansoni short chain dehydrogenase 0.0021 0.0013 0.0013
Brugia malayi Ets-domain containing protein 0.0072 0.0266 0.0388
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.017 0.0753 0.0907
Echinococcus multilocularis pyruvate kinase 0.0021 0.0013 0.0011
Schistosoma mansoni hypothetical protein 0.0213 0.0963 0.0963
Schistosoma mansoni hypothetical protein 0.0298 0.1387 0.1387
Mycobacterium ulcerans putative regulatory protein 0.0192 0.086 0.2176
Echinococcus granulosus Ankyrin 0.0029 0.0052 0.005
Echinococcus granulosus beta LACTamase domain containing family member 0.0042 0.0117 0.0114
Echinococcus granulosus neurogenic locus notch protein 0.0071 0.0262 0.026
Echinococcus multilocularis lamin 0.017 0.0753 0.0751
Trichomonas vaginalis CMGC family protein kinase 0.005 0.0159 0.1179
Brugia malayi Pre-SET motif family protein 0.0037 0.0095 0.0137
Echinococcus multilocularis Sugar transporter ERD6 protein 0.0019 0.0006 0.0004
Brugia malayi Nuclear hormone receptor E75 0.0123 0.0518 0.076
Brugia malayi laminin alpha chain 0.0071 0.0262 0.0383
Onchocerca volvulus 0.009 0.0355 0.1268
Leishmania major cytochrome P450 reductase, putative 0.0023 0.0024 0.0205
Mycobacterium ulcerans cytochrome P450 143A3 Cyp143A3 0.0033 0.0074 0.0181
Echinococcus multilocularis glutamine synthetase 0.0135 0.0579 0.0577
Schistosoma mansoni hypothetical protein 0.0213 0.0963 0.0963
Mycobacterium ulcerans fatty-acid-CoA ligase 0.002 0.0012 0.0024
Brugia malayi beta-lactamase 0.0042 0.0117 0.0169
Loa Loa (eye worm) hypothetical protein 0.0042 0.0117 0.0138
Trypanosoma cruzi hypothetical protein, conserved 0.0021 0.0013 0.0114
Trichomonas vaginalis CMGC family protein kinase 0.005 0.0159 0.1179
Loa Loa (eye worm) hypothetical protein 0.0042 0.0117 0.0138
Brugia malayi oxidoreductase 0.0021 0.0013 0.0017
Schistosoma mansoni netrin receptor unc5 0.0028 0.0051 0.0051
Plasmodium vivax SET domain protein, putative 0.0037 0.0095 0.157
Onchocerca volvulus 0.0042 0.0117 0.0408
Trypanosoma cruzi aminopeptidase, putative 0.0232 0.1059 0.8957
Echinococcus granulosus thyroid hormone receptor alpha 0.0123 0.0518 0.0516
Schistosoma mansoni 6-phosphofructokinase 0.0129 0.0547 0.0547
Schistosoma mansoni organic anion transporter 0.0027 0.0047 0.0047
Schistosoma mansoni steroid dehydrogenase 0.0021 0.0013 0.0013
Brugia malayi Carboxylesterase family protein 0.0023 0.0023 0.003
Trichomonas vaginalis conserved hypothetical protein 0.0019 0.0006 0.0029
Brugia malayi peptidase family M13 containing protein 0.0198 0.0893 0.1314
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.026 0.1198 0.1196
Echinococcus multilocularis isocitrate dehydrogenase 0.0053 0.0172 0.0169
Loa Loa (eye worm) hypothetical protein 0.0042 0.0118 0.0139
Echinococcus multilocularis netrin receptor unc 5 0.0028 0.0051 0.0049
Loa Loa (eye worm) FAD binding domain-containing protein 0.0026 0.0039 0.0044
Trypanosoma brucei Aminopeptidase M1, putative 0.0232 0.1059 0.8957
Echinococcus multilocularis puromycin sensitive aminopeptidase 0.0232 0.1059 0.1057
Trypanosoma cruzi MFS transporter, putative 0.0027 0.0047 0.0393
Leishmania major hypothetical protein, conserved 0.003 0.0058 0.0491
Toxoplasma gondii sugar transporter ST3 0.0019 0.0006 0.001
Brugia malayi AMP-binding enzyme family protein 0.0027 0.0046 0.0065
Trypanosoma brucei FAT domain/Rapamycin binding domain/Phosphatidylinositol 3- and 4-kinase, putative 0.0018 0.0002 0.0013
Trypanosoma brucei short-chain dehydrogenase, putative 0.0021 0.0013 0.0114
Loa Loa (eye worm) hypothetical protein 0.0347 0.1631 0.1967
Mycobacterium tuberculosis Probable cytochrome P450 141 Cyp141 0.0033 0.0074 0.0181
Toxoplasma gondii Kazal-type serine protease inhibitor domain-containing protein 0.0019 0.0003 0.0003
Onchocerca volvulus Protein ultraspiracle homolog 0.026 0.1198 0.4302
Plasmodium vivax 6-phosphofructokinase, putative 0.0035 0.0082 0.1354
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0104 0.0428 0.0627
Trichomonas vaginalis sugar transporter, putative 0.0019 0.0006 0.0029
Leishmania major hypothetical protein, conserved 0.0042 0.0117 0.0986
Brugia malayi Hypothetical oxidoreductase F56D1.5 0.0021 0.0013 0.0017
Trypanosoma brucei 3-ketoacyl-CoA reductase, putative 0.0021 0.0013 0.0114
Loa Loa (eye worm) hypothetical protein 0.0019 0.0006 0.0005
Echinococcus multilocularis pyruvate kinase 0.0021 0.0013 0.0011
Loa Loa (eye worm) hypothetical protein 0.0021 0.0013 0.0014
Trichomonas vaginalis short-chain dehydrogenase, putative 0.0021 0.0013 0.0085
Trypanosoma brucei pyruvate kinase 1, putative 0.004 0.011 0.0929
Toxoplasma gondii 2,4-dienoyl CoA reductase 2, peroxisomal family protein 0.0021 0.0013 0.0029
Echinococcus multilocularis solute carrier family 2, facilitated glucose 0.0019 0.0006 0.0004
Echinococcus multilocularis pyruvate kinase 0.0032 0.0068 0.0066
Plasmodium vivax hexose transporter 0.0019 0.0006 0.0065
Schistosoma mansoni Tata binding protein associated factor (M01 family) 0.0138 0.0594 0.0594
Schistosoma mansoni hypothetical protein 0.0733 0.3538 0.3538
Trypanosoma brucei glucose transporter 2A 0.0019 0.0006 0.0051
Loa Loa (eye worm) hypothetical protein 0.0021 0.0013 0.0014
Schistosoma mansoni sugar transporter 0.0019 0.0006 0.0006
Leishmania major quinonoid dihydropteridine reductase 0.0021 0.0013 0.0114
Echinococcus multilocularis GPCR, family 2 0.0033 0.0074 0.0072
Loa Loa (eye worm) hypothetical protein 0.0815 0.3945 0.4763
Trypanosoma cruzi oxidoreductase-like protein, putative 0.0021 0.0013 0.0114
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0048 0.0149 0.0147
Echinococcus multilocularis synaptic vesicle 2 protein 0.002 0.0007 0.0005
Trichomonas vaginalis PIKK family atypical protein kinase 0.0026 0.004 0.0285
Mycobacterium ulcerans 6-phosphofructokinase 0.0129 0.0547 0.1382
Loa Loa (eye worm) hypothetical protein 0.003 0.0058 0.0067
Wolbachia endosymbiont of Brugia malayi glutamine synthetase 0.0034 0.0079 1
Trypanosoma brucei short-chain dehydrogenase, putative 0.0021 0.0013 0.0114
Mycobacterium tuberculosis Possible cytochrome P450 126 Cyp126 0.0033 0.0074 0.0181
Leishmania major ATP-dependent phosphofructokinase 0.0129 0.0547 0.4625
Loa Loa (eye worm) hypothetical protein 0.0019 0.0006 0.0005
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0037 0.0095 0.0095
Toxoplasma gondii oxidoreductase, putative 0.0021 0.0013 0.0029
Loa Loa (eye worm) hypothetical protein 0.026 0.1198 0.1444
Schistosoma mansoni retinoblastoma-binding protein 4 (rbbp4) 0.0029 0.0052 0.0052
Echinococcus multilocularis mitogen activated protein kinase 0.005 0.0159 0.0157
Onchocerca volvulus 0.017 0.0753 0.2701
Leishmania major hypothetical protein, conserved 0.0257 0.1183 1
Brugia malayi photoreceptor-specific nuclear receptor 0.026 0.1198 0.1763
Entamoeba histolytica hypothetical protein 0.0298 0.1387 1
Echinococcus multilocularis aldehyde dehydrogenase, mitochondrial 0.0194 0.087 0.0868
Entamoeba histolytica phosphofructokinase, putative 0.0129 0.0547 0.3933
Trypanosoma cruzi Lanosterol 14-alpha demethylase 0.0033 0.0074 0.0623
Schistosoma mansoni nuclear hormone receptor 0.0123 0.0518 0.0518
Loa Loa (eye worm) histone methyltransferase 0.0019 0.0004 0.0003
Trypanosoma cruzi puromycin-sensitive aminopeptidase-like protein, putative 0.0138 0.0594 0.5022
Trypanosoma cruzi isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0053 0.0172 0.145
Toxoplasma gondii histone lysine acetyltransferase GCN5-B 0.0053 0.0174 0.0435
Trichomonas vaginalis sugar transporter, putative 0.0019 0.0006 0.0029
Schistosoma mansoni neuroligin 3 (S09 family) 0.0023 0.0023 0.0023
Brugia malayi FAD binding domain containing protein 0.0026 0.0039 0.0054
Schistosoma mansoni family S9 non-peptidase homologue (S09 family) 0.0023 0.0023 0.0023
Trichomonas vaginalis sugar transporter, putative 0.0019 0.0006 0.0029
Loa Loa (eye worm) hypothetical protein 0.0079 0.0302 0.0362
Trypanosoma cruzi metallo-peptidase, clan MA(E), family M1, putative 0.0138 0.0594 0.5022
Trichomonas vaginalis sugar transporter, putative 0.0019 0.0006 0.0029
Echinococcus granulosus FTZ F1 alpha 0.026 0.1198 0.1196
Toxoplasma gondii transporter, major facilitator family protein 0.0028 0.0048 0.0115
Echinococcus multilocularis solute carrier family 22 0.0019 0.0006 0.0004
Schistosoma mansoni oxidoreductase short chain dehydrogenase/reductase family 0.0021 0.0013 0.0013
Onchocerca volvulus 0.0023 0.0023 0.007
Brugia malayi Nuclear hormone receptor-like 1 0.0137 0.059 0.0868
Schistosoma mansoni hypothetical protein 0.0408 0.1933 0.1933
Echinococcus multilocularis lamin dm0 0.017 0.0753 0.0751
Loa Loa (eye worm) hypothetical protein 0.0602 0.2892 0.3491
Loa Loa (eye worm) hypothetical protein 0.0042 0.0118 0.0139
Schistosoma mansoni cell polarity protein 0.0071 0.0262 0.0262
Trichomonas vaginalis phosphofructokinase, putative 0.0035 0.0082 0.0602
Mycobacterium leprae Probable lipase LipE 0.0042 0.0117 0.0262
Mycobacterium tuberculosis Possible ketoacyl reductase 0.0021 0.0013 0.0029
Schistosoma mansoni microtubule-associated protein tau 0.2037 1 1
Echinococcus multilocularis retinol dehydrogenase 11 0.0021 0.0013 0.0011
Mycobacterium ulcerans cytochrome P450 142A3 Cyp142A3 0.0033 0.0074 0.0181
Trichomonas vaginalis sugar transporter, putative 0.0019 0.0006 0.0029
Brugia malayi hypothetical protein 0.0019 0.0006 0.0006
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0021 0.0013 0.0029
Brugia malayi orphan nuclear receptor NR2E1 0.0123 0.0518 0.076
Trypanosoma brucei NADPH--cytochrome P450 reductase, putative 0.0026 0.0039 0.0329
Brugia malayi MAP kinase sur-1 0.005 0.0159 0.0231
Brugia malayi Immunoglobulin I-set domain containing protein 0.0028 0.0051 0.0072
Onchocerca volvulus 0.0021 0.0013 0.0037
Loa Loa (eye worm) hypothetical protein 0.0021 0.0013 0.0014
Mycobacterium ulcerans lipase LipD 0.0042 0.0117 0.029
Echinococcus multilocularis Dehydrogenase:reductase SDR family 0.0021 0.0013 0.0011
Onchocerca volvulus 0.0021 0.0013 0.0037
Mycobacterium tuberculosis Probable isocitrate dehydrogenase [NADP] Icd1 (oxalosuccinate decarboxylase) (IDH) (NADP+-specific ICDH) (IDP) 0.0053 0.0172 0.0429
Onchocerca volvulus 0.0019 0.0006 0.001
Onchocerca volvulus 0.009 0.0355 0.1268
Schistosoma mansoni hypothetical protein 0.0033 0.0074 0.0074
Echinococcus multilocularis thyroid hormone receptor alpha 0.026 0.1198 0.1196
Loa Loa (eye worm) hypothetical protein 0.0061 0.0214 0.0256
Loa Loa (eye worm) hypothetical protein 0.0123 0.0518 0.0623
Plasmodium vivax DNA topoisomerase II, putative 0.0062 0.0219 0.3666
Brugia malayi Pyruvate kinase, muscle isozyme 0.004 0.011 0.0159
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.026 0.1198 0.1198
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0021 0.0013 0.0017
Trichomonas vaginalis penicillin-binding protein, putative 0.0042 0.0117 0.0859
Echinococcus multilocularis microtubule associated protein 2 0.2037 1 1
Plasmodium falciparum steroid dehydrogenase, putative 0.0021 0.0013 0.019
Brugia malayi AMP-binding enzyme family protein 0.0027 0.0046 0.0065
Loa Loa (eye worm) hypothetical protein 0.0058 0.0197 0.0235
Trypanosoma brucei hypothetical protein, conserved 0.0257 0.1183 1
Mycobacterium ulcerans zinc metalloprotease 0.0815 0.3945 1
Loa Loa (eye worm) major facilitator superfamily transporter 0.0019 0.0006 0.0005
Brugia malayi Sugar transporter family protein 0.0019 0.0006 0.0006
Toxoplasma gondii GTP-binding nuclear protein ran/tc4 0.0021 0.0014 0.0031
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0021 0.0013 0.0029
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0137 0.059 0.059
Mycobacterium ulcerans dehydrogenase 0.0021 0.0013 0.0029
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.0021 0.0014 0.0122
Mycobacterium ulcerans oxidoreductase 0.0021 0.0013 0.0029
Loa Loa (eye worm) leukotriene A4 hydrolase 0.169 0.8279 1
Trichomonas vaginalis sugar transporter, putative 0.0019 0.0006 0.0029
Schistosoma mansoni steroid dehydrogenase 0.0021 0.0013 0.0013
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0048 0.0149 0.0149
Echinococcus granulosus nuclear receptor 2DBD gamma 0.026 0.1198 0.1196
Trypanosoma brucei ATP-dependent 6-phosphofructokinase, glycosomal 0.0129 0.0547 0.4625
Trichomonas vaginalis conserved hypothetical protein 0.0067 0.0244 0.1815
Leishmania major aminopeptidase, putative,metallo-peptidase, Clan MA(E), Family M1 0.0138 0.0594 0.5022
Mycobacterium tuberculosis Probable short-chain dehydrogenase/reductase 0.0021 0.0013 0.0029
Schistosoma mansoni family M13 unassigned peptidase (M13 family) 0.0815 0.3945 0.3945
Schistosoma mansoni ataxia telangiectasia mutated (atm)-related 0.0044 0.013 0.013
Echinococcus granulosus solute carrier family 22 0.0019 0.0006 0.0004
Chlamydia trachomatis two component regulatory system sensor histidine kinase 0.007 0.0257 1
Brugia malayi Nuclear hormone receptor-like 1 0.026 0.1198 0.1763
Trichomonas vaginalis PIKK family atypical protein kinase 0.0044 0.013 0.0959
Brugia malayi hypothetical protein 0.0027 0.0047 0.0065
Brugia malayi Major Facilitator Superfamily protein 0.0019 0.0006 0.0006
Loa Loa (eye worm) hypothetical protein 0.0123 0.0518 0.0623
Brugia malayi CXXC zinc finger family protein 0.0057 0.0193 0.0282
Trichomonas vaginalis sugar transporter, putative 0.0019 0.0006 0.0029
Echinococcus multilocularis slit 2 protein 0.0071 0.0262 0.026
Mycobacterium ulcerans cytochrome P450 140A5 Cyp140A5 0.0033 0.0074 0.0181
Echinococcus granulosus BC026374 protein S09 family 0.0023 0.0023 0.0021
Schistosoma mansoni short chain dehydrogenase 0.0021 0.0013 0.0013
Schistosoma mansoni short chain dehydrogenase 0.0021 0.0013 0.0013
Loa Loa (eye worm) hypothetical protein 0.002 0.0012 0.0012
Mycobacterium ulcerans aldehyde dehydrogenase 0.0194 0.087 0.2201
Loa Loa (eye worm) hypothetical protein 0.0028 0.005 0.0057
Loa Loa (eye worm) 6-phosphofructokinase 0.0129 0.0547 0.0658
Leishmania major p450 reductase, putative 0.0026 0.0039 0.0329
Trypanosoma cruzi isocitrate dehydrogenase, putative 0.0053 0.0172 0.145
Echinococcus multilocularis disintegrin and metalloproteinase 0.0022 0.0018 0.0016
Loa Loa (eye worm) hypothetical protein 0.017 0.0753 0.0907
Mycobacterium tuberculosis Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB 0.0086 0.0337 0.085
Plasmodium vivax importin-beta 2, putative 0.0029 0.0052 0.0838
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.0042 0.0121 0.0119
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.026 0.1198 0.1196
Trypanosoma cruzi 3-keto-dihydrosphingosine reductase 0.0021 0.0013 0.0114
Leishmania major PAS-domain containing phosphoglycerate kinase, putative 0.0067 0.0244 0.2062
Plasmodium vivax NADPH-cytochrome p450 reductase, putative 0.0026 0.0039 0.062
Plasmodium falciparum conserved Plasmodium protein, unknown function 0.0021 0.0013 0.019
Toxoplasma gondii thioredoxin reductase 0.0038 0.0097 0.0242
Mycobacterium leprae probable zinc metalloprotease 0.0815 0.3945 1
Brugia malayi PAS domain containing protein 0.0259 0.1193 0.1757
Schistosoma mansoni hypothetical protein 0.0095 0.0382 0.0382
Trichomonas vaginalis PIKK family atypical protein kinase 0.0026 0.0042 0.0295
Mycobacterium tuberculosis Probable conserved integral membrane transport protein 0.0019 0.0006 0.001
Echinococcus multilocularis nuclear receptor subfamily 1 group D 0.0137 0.059 0.0588
Leishmania major 4-coumarate:coa ligase-like protein 0.0027 0.0046 0.039
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0123 0.0518 0.0516
Mycobacterium tuberculosis Probable cytochrome P450 139 Cyp139 0.0033 0.0074 0.0181
Onchocerca volvulus 0.0019 0.0006 0.001
Onchocerca volvulus 0.0021 0.0013 0.0037
Brugia malayi Hypothetical tyrosinase-like protein C02C2.1 in chromosome III 0.009 0.0355 0.0521
Leishmania major glucose transporter/membrane transporter D2, putative 0.0019 0.0006 0.0051
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.026 0.1198 0.1196
Leishmania major lanosterol 14-alpha-demethylase, putative 0.0033 0.0074 0.0623
Trypanosoma cruzi PAB1-binding protein , putative 0.003 0.0058 0.0491
Brugia malayi hypothetical protein 0.0869 0.4214 0.6213
Trichomonas vaginalis sugar transporter, putative 0.0019 0.0006 0.0029
Leishmania major NADPH-cytochrome p450 reductase-like protein 0.0026 0.0039 0.0329
Schistosoma mansoni ADAMTS5 peptidase (M12 family) 0.0103 0.0421 0.0421
Trypanosoma brucei DNA topoisomerase II alpha, putative 0.0056 0.0188 0.159
Trichomonas vaginalis sugar transporter, putative 0.0019 0.0006 0.0029
Echinococcus multilocularis carboxylesterase 5A 0.0134 0.0575 0.0573
Leishmania major short chain dehydrogenase/reductase, putative 0.0021 0.0013 0.0114
Mycobacterium leprae DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE 0.0096 0.0385 0.0944
Echinococcus granulosus solute carrier family 2 facilitated glucose 0.0019 0.0006 0.0004
Trichomonas vaginalis conserved hypothetical protein 0.0019 0.0006 0.0029
Mycobacterium tuberculosis Probable short-chain type oxidoreductase 0.0021 0.0013 0.0029
Trypanosoma brucei glucose transporter 1E 0.0019 0.0006 0.0051
Onchocerca volvulus Putative organic anion transporter 0.0027 0.0047 0.0156
Loa Loa (eye worm) hypothetical protein 0.0084 0.0325 0.0389
Trichomonas vaginalis myo-inositol transporter, putative 0.0019 0.0006 0.0029
Mycobacterium tuberculosis DNA gyrase (subunit B) GyrB (DNA topoisomerase (ATP-hydrolysing)) (DNA topoisomerase II) (type II DNA topoisomerase) 0.0021 0.0012 0.0025
Loa Loa (eye worm) hypothetical protein 0.0021 0.0013 0.0014
Echinococcus multilocularis puromycin sensitive aminopeptidase 0.0232 0.1059 0.1057
Schistosoma mansoni hepatocyte nuclear factor 4-alpha (hnf-4-alpha) 0.0123 0.0518 0.0518
Schistosoma mansoni ran 0.0021 0.0014 0.0014
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.026 0.1198 0.1444
Echinococcus granulosus puromycin sensitive aminopeptidase 0.0138 0.0594 0.0592
Schistosoma mansoni retinoic acid receptor RXR 0.026 0.1198 0.1198
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0033 0.0074 0.0072
Leishmania major target of rapamycin (TOR) kinase 2, putative 0.0044 0.013 0.1098
Mycobacterium ulcerans 3-ketoacyl-ACP reductase 0.0021 0.0013 0.0029
Trichomonas vaginalis steroid dehydrogenase, putative 0.0021 0.0013 0.0085
Brugia malayi 3-hydroxyacyl-CoA dehydrogenase type II 0.0245 0.1122 0.1651
Loa Loa (eye worm) cytochrome P450 family protein 0.0069 0.0255 0.0305
Onchocerca volvulus Glutamine synthetase homolog 0.0087 0.034 0.1214
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.026 0.1198 0.1196
Echinococcus granulosus GPCR family 2 0.0033 0.0074 0.0072
Schistosoma mansoni lamin 0.017 0.0753 0.0753
Loa Loa (eye worm) hypothetical protein 0.026 0.1198 0.1444
Loa Loa (eye worm) abnormal epIthelia family member 0.0071 0.0262 0.0314
Mycobacterium ulcerans short-chain type oxidoreductase 0.0021 0.0013 0.0029
Onchocerca volvulus Putative organic anion transporter 0.0027 0.0047 0.0156
Echinococcus granulosus neuroligin 0.0023 0.0023 0.0021
Plasmodium vivax steroid dehydrogenase, putative 0.0021 0.0013 0.019
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0042 0.0117 0.0117
Schistosoma mansoni hypothetical protein 0.0033 0.0074 0.0074
Mycobacterium tuberculosis Probable reductase 0.0086 0.0337 0.085
Loa Loa (eye worm) hypothetical protein 0.0023 0.0023 0.0025
Schistosoma mansoni ADAM17 peptidase (M12 family) 0.0218 0.0991 0.0991
Brugia malayi nuclear receptor RXR 0.0137 0.059 0.0868
Loa Loa (eye worm) oxidoreductase 0.0021 0.0013 0.0014
Schistosoma mansoni family M13 unassigned peptidase (M13 family) 0.0411 0.1946 0.1946
Schistosoma mansoni follistatin 0.0019 0.0003 0.0003
Toxoplasma gondii LsmAD domain-containing protein 0.003 0.0058 0.0142
Trypanosoma cruzi hexose transporter, putative 0.0019 0.0006 0.0051
Mycobacterium ulcerans carboxylesterase, LipT 0.0023 0.0023 0.0052
Brugia malayi Carboxylesterase family protein 0.0023 0.0023 0.003
Mycobacterium ulcerans long-chain-fatty-acid--CoA ligase 0.0027 0.0046 0.0111
Schistosoma mansoni bromodomain containing protein 0.0082 0.0318 0.0318
Mycobacterium leprae Possible regulatory protein 0.0067 0.0244 0.0586
Mycobacterium ulcerans hypothetical protein 0.0034 0.0079 0.0195
Wolbachia endosymbiont of Brugia malayi major facilitator superfamily permease 0.0019 0.0006 0.0499
Giardia lamblia DNA topoisomerase II 0.006 0.0206 1
Loa Loa (eye worm) latrophilin receptor protein 2 0.0033 0.0074 0.0087
Loa Loa (eye worm) hypothetical protein 0.0019 0.0006 0.0005
Echinococcus granulosus DNA topoisomerase 2 alpha 0.0062 0.0219 0.0217
Loa Loa (eye worm) reprolysin 0.0022 0.0018 0.0019
Plasmodium falciparum ATP-dependent 6-phosphofructokinase 0.0035 0.0082 0.1354
Brugia malayi flavodoxin family protein 0.0026 0.0039 0.0054
Brugia malayi Dehydrogenases, short chain protein 2 0.0021 0.0013 0.0017
Trypanosoma cruzi metallo-peptidase, Clan MA(E) Family M1 0.0094 0.0376 0.3177
Mycobacterium tuberculosis Conserved protein 0.0042 0.0117 0.029
Loa Loa (eye worm) hypothetical protein 0.0019 0.0006 0.0005
Trichomonas vaginalis 6-phosphofructokinase, putative 0.0035 0.0082 0.0602
Toxoplasma gondii protease inhibitor PI2 0.0019 0.0003 0.0003
Echinococcus granulosus NADPH dependent diflavin oxidoreductase 1 0.0026 0.0039 0.0037
Trichomonas vaginalis PIKK family atypical protein kinase 0.0024 0.0029 0.02
Echinococcus multilocularis 3 ketodihydrosphingosine reductase 0.0021 0.0013 0.0011
Trypanosoma cruzi short chain dehydrogenase/reductase, putative 0.0021 0.0013 0.0114
Onchocerca volvulus 0.0065 0.0233 0.0827
Echinococcus granulosus retinol dehydrogenase 11 0.0021 0.0013 0.0011
Loa Loa (eye worm) peptidase family M1 containing protein 0.0485 0.2314 0.2793
Brugia malayi nuclear hormone receptor 0.026 0.1198 0.1763
Trichomonas vaginalis short-chain dehydrogenase, putative 0.0021 0.0013 0.0085
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0021 0.0013 0.0029
Brugia malayi Kazal-type serine protease inhibitor domain containing protein 0.0019 0.0003 0.0002
Toxoplasma gondii sterol carrier protein-2 HAD-2SCP-2 0.0021 0.0013 0.0029
Mycobacterium ulcerans citrate (pro-3S)-lyase subunit beta 0.003 0.0057 0.0139
Schistosoma mansoni nuclear hormone receptor superfamily protein-related 0.0123 0.0518 0.0518
Echinococcus granulosus follistatin 0.0019 0.0003 0.0001
Brugia malayi PHD-finger family protein 0.0037 0.0093 0.0134
Mycobacterium ulcerans short chain dehydrogenase 0.0021 0.0013 0.0029
Echinococcus granulosus ankyrin repeat and death domain containing protein 0.0028 0.0051 0.0049
Mycobacterium ulcerans short-chain dehydrogenase 0.0021 0.0013 0.0029
Onchocerca volvulus Pyruvate kinase homolog 0.004 0.011 0.0384
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.0021 0.0014 0.0122
Trypanosoma brucei importin beta-1 subunit, putative 0.0029 0.0052 0.0438
Loa Loa (eye worm) aryl Hydrocarbon receptor Associated protein family member 0.0067 0.0244 0.0292
Loa Loa (eye worm) cytoplasmic intermediate filament protein 0.0091 0.0362 0.0434
Echinococcus multilocularis carbonyl reductase 1 0.0021 0.0013 0.0011
Echinococcus granulosus epidermal retinal dehydrogenase 2 0.0021 0.0013 0.0011
Echinococcus multilocularis survival motor neuron protein 1 0.0467 0.2224 0.2223
Trichomonas vaginalis sugar transporter, putative 0.0019 0.0006 0.0029
Onchocerca volvulus Dehydrogenase\/reductase SDR family member 1 homolog 0.0021 0.0013 0.0037
Mycobacterium tuberculosis Probable dehydrogenase 0.0021 0.0013 0.0029
Schistosoma mansoni glucose transporter 0.0019 0.0006 0.0006
Onchocerca volvulus 0.0027 0.0047 0.0156
Mycobacterium ulcerans sugar-transport integral membrane protein SugI 0.0019 0.0006 0.001
Plasmodium falciparum M1-family alanyl aminopeptidase, putative 0.0138 0.0594 1
Trichomonas vaginalis sugar transporter, putative 0.0019 0.0006 0.0029
Giardia lamblia Nitric oxide synthase, inducible 0.0023 0.0024 0.1086
Brugia malayi Peptidase family M1 containing protein 0.0579 0.278 0.4096
Trypanosoma cruzi Phosphatidylinositol 3-kinase tor2 0.0044 0.013 0.1098
Plasmodium vivax ataxin-2 like protein, putative 0.003 0.0058 0.0943
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0245 0.1122 0.2839
Trypanosoma brucei short-chain dehydrogenase, putative 0.0021 0.0013 0.0114
Onchocerca volvulus 0.0021 0.0013 0.0037
Loa Loa (eye worm) hypothetical protein 0.0616 0.2962 0.3576
Echinococcus granulosus Nuclear hormone receptor HR96 0.0123 0.0518 0.0516
Loa Loa (eye worm) hypothetical protein 0.0104 0.0428 0.0514
Mycobacterium tuberculosis Putative ferredoxin reductase 0.0086 0.0337 0.085
Mycobacterium tuberculosis POSSIBLE PARA-NITROBENZYL ESTERASE (FRAGMENT) 0.0023 0.0023 0.0052
Schistosoma mansoni hypothetical protein 0.0024 0.0031 0.0031
Mycobacterium tuberculosis Probable dehydrogenase/reductase 0.0021 0.0013 0.0029
Plasmodium falciparum glutathione reductase 0.0038 0.0097 0.161
Schistosoma mansoni short chain dehydrogenase 0.0021 0.0013 0.0013
Loa Loa (eye worm) hypothetical protein 0.0071 0.0264 0.0316
Trichomonas vaginalis sugar transporter, putative 0.0019 0.0006 0.0029
Echinococcus granulosus pyruvate kinase 0.004 0.011 0.0108
Trypanosoma brucei THT1 - hexose transporter, putative 0.0019 0.0006 0.0051
Loa Loa (eye worm) transcription factor SMAD2 0.0141 0.061 0.0734
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0057 0.0195 0.0195
Echinococcus multilocularis pikachurin 0.0071 0.0262 0.026
Loa Loa (eye worm) carboxylesterase 0.0023 0.0023 0.0025
Mycobacterium tuberculosis Probable cytochrome P450 143 Cyp143 0.0033 0.0074 0.0181
Loa Loa (eye worm) hypothetical protein 0.0023 0.0023 0.0025
Brugia malayi nuclear receptor RXR 0.0123 0.0518 0.076
Leishmania major isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0053 0.0172 0.145
Trypanosoma cruzi NADPH-dependent FMN/FAD containing oxidoreductase, putative 0.0026 0.0039 0.0329
Mycobacterium tuberculosis Probable oxidoreductase 0.0021 0.0013 0.0029
Onchocerca volvulus 0.0019 0.0006 0.001
Trypanosoma cruzi apurinic/apyrimidinic endonuclease 0.0019 0.0002 0.0019
Leishmania major glucose transporter, lmgt3 0.0019 0.0006 0.0051
Echinococcus granulosus organic anion transporting polypeptide 30B 0.0027 0.0047 0.0044
Trypanosoma cruzi DNA topoisomerase II, putative 0.0056 0.0188 0.159
Brugia malayi sodium-independent organic anion transporter family protein 0.0027 0.0047 0.0065
Brugia malayi Probable DNA topoisomerase II 0.0062 0.0219 0.032
Trypanosoma cruzi ATP-dependent 6-phosphofructokinase, glycosomal 0.0129 0.0547 0.4625
Trichomonas vaginalis conserved hypothetical protein 0.0019 0.0006 0.0029
Trichomonas vaginalis CMGC family protein kinase 0.005 0.0159 0.1179
Loa Loa (eye worm) zinc metallopeptidase 4 0.0198 0.0893 0.1076
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0048 0.0149 0.0149
Echinococcus multilocularis a disintegrin and metalloproteinase with 0.0103 0.0421 0.0419
Trichomonas vaginalis penicillin-binding protein, putative 0.0042 0.0117 0.0859
Mycobacterium tuberculosis Conserved protein 0.0042 0.0117 0.029
Mycobacterium ulcerans cytochrome P450 126A3 Cyp126A3 0.0033 0.0074 0.0181
Toxoplasma gondii oxidoreductase, short chain dehydrogenase/reductase family protein 0.0021 0.0013 0.0029
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0123 0.0518 0.0516
Leishmania major target of rapamycin (TOR) kinase 1, putative 0.0044 0.013 0.1098
Trypanosoma cruzi hexose transporter, putative 0.0019 0.0006 0.0051
Echinococcus granulosus nuclear receptor subfamily 1 group D 0.0137 0.059 0.0588
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0021 0.0013 0.0029
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.026 0.1198 0.1444
Schistosoma mansoni ecdysone-induced protein 78c (dr-78) 0.0137 0.059 0.059
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0123 0.0518 0.0516
Trypanosoma brucei NADPH-cytochrome p450 reductase, putative 0.0026 0.0039 0.0329
Onchocerca volvulus 0.017 0.0753 0.2701
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.026 0.1198 0.1198
Schistosoma mansoni nuclear receptor nhr-48 0.0123 0.0518 0.0518
Onchocerca volvulus 0.0192 0.086 0.3085
Trichomonas vaginalis PIKK family atypical protein kinase 0.0024 0.0029 0.0199
Trypanosoma cruzi importin beta-1 subunit, putative 0.0023 0.0025 0.0212
Trichomonas vaginalis estradiol 17 beta-dehydrogenase, putative 0.0021 0.0013 0.0085
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0037 0.0095 0.0236
Echinococcus granulosus NADPH cytochrome P450 reductase 0.0026 0.0039 0.0037
Schistosoma mansoni short chain dehydrogenase 0.0021 0.0013 0.0013
Leishmania major oxidoreductase-like protein 0.0021 0.0013 0.0114
Toxoplasma gondii Kazal-type serine protease inhibitor domain-containing protein 0.0019 0.0003 0.0003
Echinococcus granulosus single minded 2 0.0192 0.086 0.0858
Onchocerca volvulus 0.0027 0.0047 0.0156
Mycobacterium tuberculosis Possible iron-regulated short-chain dehydrogenase/reductase 0.0021 0.0013 0.0029
Loa Loa (eye worm) hypothetical protein 0.0021 0.0013 0.0014
Onchocerca volvulus Sepiapterin reductase homolog 0.0021 0.0013 0.0037
Plasmodium vivax histone acetyltransferase GCN5, putative 0.0053 0.0174 0.2901
Brugia malayi beta-lactamase family protein 0.0042 0.0117 0.0169
Schistosoma mansoni nuclear receptor 0.0123 0.0518 0.0518
Trichomonas vaginalis PIKK family atypical protein kinase 0.0024 0.0029 0.02
Brugia malayi GTP-binding nuclear protein RAN/TC4 0.0021 0.0014 0.0018
Toxoplasma gondii oxidoreductase, short chain dehydrogenase/reductase family protein 0.0021 0.0013 0.0029
Schistosoma mansoni glutamine synthetase 1 2 (glutamate-amonia ligase) (gs) 0.0135 0.0579 0.0579
Brugia malayi hypothetical protein 0.0065 0.0233 0.034
Echinococcus granulosus geminin 0.0733 0.3538 0.3537
Schistosoma mansoni pyruvate kinase 0.0021 0.0013 0.0013
Schistosoma mansoni cellular tumor antigen P53 0.0049 0.0155 0.0155
Brugia malayi Nuclear hormone receptor family member nhr-25 0.026 0.1198 0.1763
Trypanosoma brucei pyruvate kinase 1 0.004 0.011 0.0929
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.026 0.1198 0.1444
Schistosoma mansoni sugar transporter 0.0019 0.0006 0.0006
Schistosoma mansoni family S9 non-peptidase homologue (S09 family) 0.0134 0.0575 0.0575
Echinococcus granulosus adam 0.0038 0.0098 0.0096
Trichomonas vaginalis soluble guanylate cyclase gcy, putative 0.0067 0.0244 0.1815
Schistosoma mansoni agrin 0.0019 0.0003 0.0003
Schistosoma mansoni acetylcholinesterase 0.0023 0.0023 0.0023
Leishmania major 4-coumarate:coa ligase-like protein 0.0027 0.0046 0.039
Loa Loa (eye worm) hypothetical protein 0.0021 0.0013 0.0014
Trichomonas vaginalis carboxylesterase domain containing protein, putative 0.0023 0.0023 0.0154
Trypanosoma cruzi cytochrome P450, putative 0.0069 0.0255 0.2152
Onchocerca volvulus 0.0042 0.0117 0.0408
Brugia malayi acetyltransferase, GNAT family protein 0.0174 0.0773 0.1137
Loa Loa (eye worm) hypothetical protein 0.009 0.0355 0.0427
Mycobacterium ulcerans cytochrome P450 51B1 Cyp51B1 0.0033 0.0074 0.0181
Mycobacterium ulcerans long-chain fatty-acid CoA ligase 0.0027 0.0046 0.0111
Trichomonas vaginalis PIKK family atypical protein kinase 0.0033 0.0074 0.0536
Schistosoma mansoni ran 0.0021 0.0014 0.0014
Mycobacterium tuberculosis Possible multi-functional enzyme with acyl-CoA-reductase activity AcrA1 0.0021 0.0013 0.0029
Onchocerca volvulus 0.0027 0.0047 0.0156
Trichomonas vaginalis sugar transporter, putative 0.0019 0.0006 0.0029
Loa Loa (eye worm) acetylcholinesterase 1 0.0134 0.0575 0.0692
Trypanosoma brucei PAB1-binding protein , putative 0.003 0.0058 0.0491
Echinococcus granulosus aldehyde dehydrogenase mitochondrial 0.0194 0.087 0.0868
Onchocerca volvulus 0.009 0.0355 0.1268
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0048 0.0149 0.0147
Echinococcus granulosus mitogen activated protein kinase 0.005 0.0159 0.0157
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0057 0.0195 0.0195
Brugia malayi Nuclear hormone receptor family member nhr-14 0.026 0.1198 0.1763
Loa Loa (eye worm) hypothetical protein 0.0137 0.059 0.0711
Onchocerca volvulus 0.0021 0.0013 0.0037
Plasmodium vivax glutamine synthetase, putative 0.0087 0.034 0.5715
Trypanosoma brucei DNA topoisomerase ii 0.0049 0.0153 0.1295
Loa Loa (eye worm) hypothetical protein 0.0467 0.2224 0.2685
Brugia malayi Pre-SET motif family protein 0.0253 0.1161 0.1709
Echinococcus multilocularis leukotriene A 4 hydrolase 0.169 0.8279 0.8279
Schistosoma mansoni short chain dehydrogenase 0.0021 0.0013 0.0013
Leishmania major quinonoid dihydropteridine reductase 0.0021 0.0013 0.0114
Echinococcus granulosus carbonyl reductase 1 0.0021 0.0013 0.0011
Mycobacterium tuberculosis Possible oxidoreductase 0.0021 0.0013 0.0029
Brugia malayi hypothetical protein 0.0019 0.0006 0.0006
Trypanosoma brucei beta-D-hydroxybutyrate dehydrogenase 0.0021 0.0013 0.0114
Onchocerca volvulus Dehydrogenase\/reductase SDR family member 13 homolog 0.0021 0.0013 0.0037
Echinococcus multilocularis zinc finger protein 0.0031 0.0062 0.006
Echinococcus multilocularis dnaJ subfamily B 0.0408 0.1933 0.1931
Onchocerca volvulus 0.0037 0.0095 0.0331
Treponema pallidum diphosphate--fructose-6-phosphate 1-phosphotransferase 0.0035 0.0082 0.1471
Trichomonas vaginalis Clan MA, family M1, aminopeptidase N-like metallopeptidase 0.0232 0.1059 0.7942
Onchocerca volvulus 0.0019 0.0006 0.001
Trichomonas vaginalis glucose transporter, putative 0.0019 0.0006 0.0029
Mycobacterium ulcerans short chain dehydrogenase 0.0021 0.0013 0.0029
Toxoplasma gondii glutamine synthetase, type I, putative 0.0087 0.034 0.0858
Echinococcus multilocularis tyrosine protein phosphatase non receptor type 0.0379 0.1788 0.1786
Trypanosoma brucei trypanothione reductase 0.0038 0.0097 0.0824
Brugia malayi Disintegrin family protein 0.0022 0.0018 0.0024
Trichomonas vaginalis adenylate cyclase, type VII, putative 0.0067 0.0244 0.1815
Loa Loa (eye worm) intermediate filament protein 0.017 0.0753 0.0907
Mycobacterium tuberculosis Probable shortchain dehydrogenase 0.0021 0.0013 0.0029
Trypanosoma cruzi short-chain dehydrogenase, putative 0.0021 0.0013 0.0114
Schistosoma mansoni importin beta-1 0.0029 0.0052 0.0052
Echinococcus granulosus 3 hydroxyacyl coenzyme A dehydrogenase type 2 0.0245 0.1122 0.112
Mycobacterium ulcerans ketoacyl reductase 0.0021 0.0013 0.0029
Mycobacterium ulcerans short chain dehydrogenase 0.0021 0.0013 0.0029
Loa Loa (eye worm) hypothetical protein 0.0028 0.0047 0.0054
Loa Loa (eye worm) hypothetical protein 0.0019 0.0003 0.0001
Schistosoma mansoni short-chain dehydrogenase/reductase 0.0021 0.0013 0.0013
Plasmodium falciparum ataxin-2 like protein, putative 0.003 0.0058 0.0943
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0053 0.0172 0.0169
Mycobacterium tuberculosis Probable oxidoreductase 0.0021 0.0013 0.0029
Treponema pallidum diphosphate--fructose-6-phosphate 1-phosphotransferase 0.0129 0.0547 1
Loa Loa (eye worm) hypothetical protein 0.0138 0.0594 0.0715
Trichomonas vaginalis phosphofructokinase, putative 0.0129 0.0547 0.4092
Echinococcus multilocularis ankyrin repeat and death domain containing protein 0.0028 0.0051 0.0049
Giardia lamblia Pyruvate kinase 0.0021 0.0013 0.052
Schistosoma mansoni chondroitin sulfate proteoglycan-related 0.0071 0.0262 0.0262
Brugia malayi secreted modular calcium-binding protein 1 0.0019 0.0003 0.0002
Trypanosoma cruzi metallo-peptidase, Clan MA(E) Family M1 0.0138 0.0594 0.5022
Trypanosoma brucei phosphatidylinositol 4-kinase, putative 0.0044 0.013 0.1098
Chlamydia trachomatis DNA gyrase subunit B 0.0021 0.0012 0.0007
Giardia lamblia GTOR 0.0044 0.013 0.6275
Loa Loa (eye worm) hypothetical protein 0.0123 0.0518 0.0623
Loa Loa (eye worm) hypothetical protein 0.0027 0.0047 0.0054
Schistosoma mansoni glucose transport protein 0.0019 0.0006 0.0006
Echinococcus multilocularis nuclear factor of activated T cells 5 0.0146 0.0631 0.0629
Plasmodium vivax DNA gyrase subunit B, putative 0.0021 0.0012 0.0165
Trichomonas vaginalis PIKK family atypical protein kinase 0.0033 0.0074 0.0536
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0048 0.0149 0.0149
Echinococcus granulosus disintegrin and metalloproteinase 0.0022 0.0018 0.0016
Trypanosoma cruzi 2,4-dihydroxyhept-2-ene-1,7-dioic acid aldolase, putative 0.003 0.0057 0.0481
Brugia malayi RNA, U transporter 1 0.0081 0.0313 0.0458
Trichomonas vaginalis PIKK family atypical protein kinase 0.0044 0.013 0.0959
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD3 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0019 0.0006 0.001
Trypanosoma cruzi cytochrome p450-like protein, putative 0.0033 0.0074 0.0623
Trichomonas vaginalis glucose transporter, putative 0.0019 0.0006 0.0029
Plasmodium vivax hypothetical protein, conserved 0.0042 0.0117 0.1932
Mycobacterium tuberculosis NAD(P)H quinone reductase LpdA 0.0096 0.0385 0.097
Giardia lamblia Histone acetyltransferase GCN5 0.0046 0.0139 0.6738
Mycobacterium tuberculosis Probable lipase LipE 0.0042 0.0117 0.029
Plasmodium falciparum ataxin-2 like protein, putative 0.003 0.0058 0.0943
Onchocerca volvulus 0.0023 0.0023 0.007
Trichomonas vaginalis PIKK family atypical protein kinase 0.0024 0.0029 0.0199
Onchocerca volvulus 0.0019 0.0006 0.001
Echinococcus multilocularis retinol dehydrogenase 13 0.0021 0.0013 0.0011
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0021 0.0013 0.0017
Schistosoma mansoni laminin gamma-3 chain 0.0071 0.0262 0.0262
Mycobacterium tuberculosis Possible penicillin-binding protein 0.0266 0.1228 0.3108
Brugia malayi Carboxylesterase family protein 0.0134 0.0575 0.0845
Mycobacterium ulcerans oxidoreductase 0.0021 0.0013 0.0029
Mycobacterium ulcerans short-chain dehydrogenase 0.0021 0.0013 0.0029
Toxoplasma gondii pyruvate kinase PyK1 0.004 0.011 0.0273
Schistosoma mansoni glucose transport protein 0.0019 0.0006 0.0006
Loa Loa (eye worm) hypothetical protein 0.0616 0.2962 0.3576
Echinococcus granulosus carboxylesterase 5A 0.0134 0.0575 0.0573
Brugia malayi Ets-domain containing protein 0.0072 0.0266 0.0388
Echinococcus multilocularis carbonyl reductase 1 0.0021 0.0013 0.0011
Echinococcus multilocularis pyruvate kinase 0.0021 0.0013 0.0011
Brugia malayi Protein-tyrosine phosphatase containing protein 0.0379 0.1788 0.2634
Leishmania major glucose transporter, lmgt1 0.0019 0.0006 0.0051
Schistosoma mansoni glucose transport protein 0.0019 0.0006 0.0006
Loa Loa (eye worm) hypothetical protein 0.0123 0.0518 0.0623
Onchocerca volvulus 0.0019 0.0006 0.001
Trichomonas vaginalis bromodomain-containing protein, putative 0.0053 0.0174 0.129
Brugia malayi metalloprotease disintegrin 16 with thrombospondin type I motif 0.0103 0.0421 0.0617
Trichomonas vaginalis short-chain dehydrogenase, putative 0.0021 0.0013 0.0085
Echinococcus multilocularis tumor protein p63 0.0337 0.1581 0.158
Echinococcus granulosus ecdysone induced protein 78C 0.026 0.1198 0.1196
Mycobacterium ulcerans aminopeptidase N PepN 0.0138 0.0594 0.1501
Loa Loa (eye worm) hypothetical protein 0.0019 0.0006 0.0005
Loa Loa (eye worm) hypothetical protein 0.0029 0.0052 0.006
Onchocerca volvulus 0.0023 0.0023 0.007
Loa Loa (eye worm) hypothetical protein 0.0134 0.0575 0.0692
Trypanosoma cruzi mitogen activated protein kinase 4, putative 0.005 0.0159 0.1346
Toxoplasma gondii transporter, major facilitator family protein 0.0019 0.0006 0.001
Schistosoma mansoni family S9 non-peptidase homologue (S09 family) 0.0023 0.0023 0.0023
Onchocerca volvulus Putative transporter 0.0019 0.0006 0.001
Trypanosoma cruzi quinonoid dihydropteridine reductase, putative 0.0021 0.0013 0.0114
Trichomonas vaginalis PIKK family atypical protein kinase 0.0033 0.0074 0.0536
Giardia lamblia Hypothetical protein 0.0021 0.0013 0.0554
Trichomonas vaginalis spcc417.12 protein, putative 0.0023 0.0023 0.0154
Brugia malayi 6-phosphofructokinase 0.0129 0.0547 0.0803
Schistosoma mansoni sugar transporter 0.0019 0.0006 0.0006
Schistosoma mansoni neprilysin-2 (M13 family) 0.0411 0.1946 0.1946
Trichomonas vaginalis PIKK family atypical protein kinase 0.0038 0.0098 0.0718
Mycobacterium ulcerans cytochrome P450 124A1, Cyp124A1 0.0033 0.0074 0.0181
Mycobacterium tuberculosis Probable dicarboxylic acid transport integral membrane protein KgtP (dicarboxylate transporter) 0.0019 0.0006 0.001
Trypanosoma cruzi mitogen activated protein kinase 2, putative 0.005 0.0159 0.1346
Echinococcus granulosus synaptic vesicle 2 protein 0.002 0.0007 0.0005
Trypanosoma brucei glutamine synthetase, putative 0.0135 0.0579 0.4895
Leishmania major mitochondrial DNA topoisomerase II 0.0049 0.0153 0.1295
Loa Loa (eye worm) hypothetical protein 0.0033 0.0074 0.0087
Schistosoma mansoni nuclear hormone receptor 0.0123 0.0518 0.0518
Trypanosoma cruzi beta-ketoacyl-ACP reductase 2, putative 0.0021 0.0013 0.0114
Loa Loa (eye worm) pyruvate kinase-PB 0.0028 0.005 0.0057
Mycobacterium ulcerans cytochrome P450 185A4 Cyp185A4 0.0069 0.0255 0.064
Echinococcus multilocularis puromycin sensitive aminopeptidase 0.0232 0.1059 0.1057
Trypanosoma brucei sugar transporter, putative 0.0019 0.0006 0.0051
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0042 0.0117 0.0169
Toxoplasma gondii CMGC kinase, MAPK family (ERK) MAPK-1 0.005 0.0159 0.0398
Entamoeba histolytica acyl-coA synthetase, putative 0.0027 0.0046 0.0317
Brugia malayi nuclear hormone receptor family member odr-7 0.0123 0.0518 0.076
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0023 0.0025 0.0172
Onchocerca volvulus 0.0021 0.0013 0.0037
Echinococcus granulosus GA binding protein alpha chain 0.0072 0.0266 0.0263
Brugia malayi Nuclear hormone receptor family member nhr-19 0.026 0.1198 0.1763
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.0078 0.0297 0.0295
Trypanosoma brucei Phosphatidylinositol 3-kinase tor1 0.0044 0.013 0.1098
Schistosoma mansoni hypothetical protein 0.0061 0.0213 0.0213
Schistosoma mansoni retinal dehydrogenase 0.0021 0.0013 0.0013
Loa Loa (eye worm) hypothetical protein 0.0042 0.0117 0.0138
Trichomonas vaginalis conserved hypothetical protein 0.0067 0.0244 0.1815
Loa Loa (eye worm) follicle stimulating hormone receptor 0.0468 0.2226 0.2686
Trichomonas vaginalis short-chain dehydrogenase, putative 0.0021 0.0013 0.0085
Brugia malayi nuclear receptor NHR-88 0.0123 0.0518 0.076
Schistosoma mansoni zinc finger protein 0.0031 0.0062 0.0062
Echinococcus granulosus tyrosine protein phosphatase non receptor type 0.0379 0.1788 0.1786
Mycobacterium tuberculosis Probable short-chain type dehydrogenase/reductase 0.0021 0.0013 0.0029
Loa Loa (eye worm) bromodomain containing protein 0.0025 0.0035 0.0039
Entamoeba histolytica acyl-CoA synthetase, putative 0.0027 0.0046 0.0317
Onchocerca volvulus 0.0019 0.0006 0.001
Loa Loa (eye worm) ShTK domain-containing protein 0.009 0.0355 0.0427
Mycobacterium ulcerans short chain dehydrogenase 0.0021 0.0013 0.0029
Loa Loa (eye worm) hypothetical protein 0.0602 0.2892 0.3491
Trichomonas vaginalis PIKK family atypical protein kinase 0.0044 0.013 0.0959
Echinococcus multilocularis FTZ F1 alpha 0.026 0.1198 0.1196
Echinococcus granulosus Blood coagulation inhibitor Disintegrin 0.0137 0.0589 0.0587
Entamoeba histolytica aminopeptidase, putative 0.0232 0.1059 0.7633
Toxoplasma gondii isocitrate dehydrogenase 0.0053 0.0172 0.0429
Brugia malayi hypothetical protein 0.0021 0.0013 0.0017
Mycobacterium ulcerans cytochrome P450 189A7 Cyp189A7 0.0033 0.0074 0.0181
Trypanosoma brucei beta-ketoacyl-ACP reductase 3, putative 0.0021 0.0013 0.0114
Trypanosoma brucei protein kinase, putative 0.005 0.0159 0.1346
Plasmodium falciparum pyruvate kinase 2 0.0021 0.0013 0.0179
Echinococcus granulosus acetylcholinesterase 0.0134 0.0575 0.0573
Loa Loa (eye worm) nucleolar RNA-associated protein alpha 0.0305 0.142 0.1713
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0048 0.0149 0.0177
Echinococcus multilocularis nuclear receptor subfamily 4 group A 0.0123 0.0518 0.0516
Echinococcus granulosus adam 17 protease 0.024 0.1099 0.1097
Echinococcus granulosus GTP binding nuclear protein Ran 0.0021 0.0014 0.0012
Onchocerca volvulus 0.0027 0.0047 0.0156
Trypanosoma cruzi 2,4-dihydroxyhept-2-ene-1,7-dioic acid aldolase, putative 0.003 0.0057 0.0481
Brugia malayi ShTK domain containing protein 0.009 0.0355 0.0521
Loa Loa (eye worm) pyruvate kinase 0.004 0.011 0.013
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0253 0.1161 0.14
Toxoplasma gondii histone lysine acetyltransferase GCN5-A 0.0053 0.0174 0.0435
Mycobacterium tuberculosis Probable short-chain type dehydrogenase/reductase 0.0245 0.1122 0.2839
Echinococcus multilocularis importin subunit beta 1 0.0029 0.0052 0.005
Mycobacterium tuberculosis Probable zinc metalloprotease Zmp1 0.0815 0.3945 1
Mycobacterium tuberculosis Probable cytochrome P450 124 Cyp124 0.0033 0.0074 0.0181
Trichomonas vaginalis PIKK family atypical protein kinase 0.0026 0.0042 0.0295
Leishmania major protein kinase, putative 0.0068 0.0246 0.2081
Loa Loa (eye worm) hypothetical protein 0.026 0.1198 0.1444
Onchocerca volvulus 0.0288 0.1334 0.4794
Mycobacterium tuberculosis Probable oxidoreductase 0.0021 0.0013 0.0029
Toxoplasma gondii phosphofructokinase PFKII 0.0035 0.0082 0.0203
Echinococcus granulosus nuclear receptor 2DBD gamma 0.026 0.1198 0.1196
Echinococcus granulosus Solute carrier organic anion transporter family 0.0027 0.0047 0.0044
Loa Loa (eye worm) pyruvate kinase 0.004 0.011 0.013
Echinococcus multilocularis puromycin sensitive aminopeptidase 0.0232 0.1059 0.1057
Mycobacterium ulcerans short chain dehydrogenase 0.0021 0.0013 0.0029
Loa Loa (eye worm) DR-78 0.0123 0.0518 0.0623
Leishmania major hypothetical protein, conserved 0.0021 0.0013 0.0114
Mycobacterium tuberculosis Decaprenylphosphoryl-D-2-keto erythro pentose reductase 0.0021 0.0013 0.0029
Leishmania major puromycin-sensitive aminopeptidase-like protein,metallo-peptidase, Clan MA(E), Family M1 0.0138 0.0594 0.5022
Loa Loa (eye worm) hypothetical protein 0.026 0.1198 0.1444
Trypanosoma cruzi hypothetical protein, conserved 0.0042 0.0117 0.0986
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0104 0.0428 0.0514
Echinococcus granulosus nuclear receptor subfamily 4 group A 0.0123 0.0518 0.0516
Echinococcus multilocularis estradiol 17 beta dehydrogenase 12 0.0021 0.0013 0.0011
Trichomonas vaginalis PIKK family atypical protein kinase 0.0033 0.0074 0.0536
Leishmania major cytochrome p450-like protein 0.0033 0.0074 0.0623
Mycobacterium ulcerans cytochrome P450 125A7 Cyp125A7 0.0033 0.0074 0.0181
Schistosoma mansoni nuclear transcription factor X-box binding 1 (nfx1) 0.0019 0.0006 0.0006
Leishmania major aldehyde dehydrogenase, mitochondrial precursor 0.0194 0.087 0.7357
Trichomonas vaginalis PIKK family atypical protein kinase 0.003 0.0058 0.0416
Trichomonas vaginalis phosphofructokinase, putative 0.0035 0.0082 0.0602
Echinococcus multilocularis atpase aaa+ type core atpase aaa type core 0.1741 0.853 0.853
Loa Loa (eye worm) hypothetical protein 0.0028 0.0051 0.0059
Trypanosoma brucei isocitrate dehydrogenase, putative 0.0053 0.0172 0.145
Brugia malayi Nuclear hormone receptor family member nhr-1 0.026 0.1198 0.1763
Schistosoma mansoni short chain dehydrogenase 0.0021 0.0013 0.0013
Schistosoma mansoni subfamily M12B unassigned peptidase (M12 family) 0.0022 0.0018 0.0018
Toxoplasma gondii 3-ketoacyl-CoA reductase, putative 0.0021 0.0013 0.0029
Brugia malayi Dehydrogenases, short chain protein 30 0.0021 0.0013 0.0017
Loa Loa (eye worm) hypothetical protein 0.0138 0.0594 0.0715
Onchocerca volvulus 0.0123 0.0518 0.1853
Echinococcus multilocularis Aryl hydrocarbon receptor nuclear 0.0067 0.0244 0.0242
Brugia malayi Latrophilin receptor protein 2 0.0033 0.0074 0.0106
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0122 0.0517 0.0517
Trichomonas vaginalis cat eye syndrome critical region protein 2, cscr2, putative 0.0053 0.0174 0.129
Mycobacterium ulcerans dehydrogenase/reductase 0.0021 0.0013 0.0029
Trypanosoma cruzi hypothetical protein, conserved 0.0021 0.0013 0.0114
Mycobacterium tuberculosis Probable short-chain type dehydrogenase/reductase 0.0021 0.0013 0.0029
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0021 0.0013 0.0029
Loa Loa (eye worm) pyruvate kinase 0.004 0.011 0.013
Toxoplasma gondii facilitative glucose transporter GT1 0.0019 0.0006 0.001
Schistosoma mansoni short chain dehydrogenase 0.0021 0.0013 0.0013
Echinococcus granulosus methyl CpG binding domain protein 2 0.002 0.001 0.0008
Trichomonas vaginalis sugar transporter, putative 0.0019 0.0006 0.0029
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.0095 0.0382 0.0561
Brugia malayi Peptidase family M1 containing protein 0.0138 0.0594 0.0873
Brugia malayi Cytochrome P450 family protein 0.0069 0.0255 0.0372
Loa Loa (eye worm) hypothetical protein 0.0042 0.0117 0.0138
Plasmodium vivax acyl-CoA synthetase, putative 0.002 0.0012 0.0163
Schistosoma mansoni ap endonuclease 0.0019 0.0002 0.0002
Loa Loa (eye worm) hypothetical protein 0.0029 0.0052 0.006
Loa Loa (eye worm) oxidoreductase 0.0021 0.0013 0.0014
Toxoplasma gondii sugar transporter ST2 0.0019 0.0006 0.001
Mycobacterium ulcerans citrate lyase beta subunit, CitE_2 0.003 0.0057 0.0139
Echinococcus granulosus solute carrier family 2 facilitated glucose 0.0019 0.0006 0.0004
Trypanosoma cruzi mitochondrial DNA topoisomerase II, putative 0.0049 0.0153 0.1295
Brugia malayi 6-phosphofructokinase 0.0129 0.0547 0.0803
Leishmania major aminopeptidase-like protein,metallo-peptidase, Clan MA(E), Family M1 0.0232 0.1059 0.8957
Echinococcus granulosus death domain containing protein 0.0028 0.0051 0.0049
Trichomonas vaginalis pyruvate kinase, putative 0.004 0.011 0.0809
Loa Loa (eye worm) hypothetical protein 0.0137 0.059 0.0711
Trypanosoma brucei glucose transporter, putative 0.0019 0.0006 0.0051
Brugia malayi Peptidase family M13 containing protein 0.0815 0.3945 0.5815
Echinococcus granulosus puromycin sensitive aminopeptidase 0.0138 0.0594 0.0592
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0021 0.0013 0.0017
Schistosoma mansoni hypothetical protein 0.0213 0.0963 0.0963
Loa Loa (eye worm) hypothetical protein 0.0459 0.2182 0.2633
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0033 0.0074 0.0072
Brugia malayi MH2 domain containing protein 0.0141 0.061 0.0896
Onchocerca volvulus 0.0021 0.0013 0.0037
Mycobacterium ulcerans short chain dehydrogenase 0.0021 0.0013 0.0029
Loa Loa (eye worm) hypothetical protein 0.0616 0.2962 0.3576
Loa Loa (eye worm) dehydrogenase 0.0021 0.0013 0.0014
Leishmania major short chain dehydrogenase, putative 0.0021 0.0013 0.0114
Mycobacterium tuberculosis Possible cytochrome P450 135A1 Cyp135A1 0.0033 0.0074 0.0181
Trypanosoma brucei NADPH--cytochrome P450 reductase, putative 0.0026 0.0039 0.0329
Leishmania major cytochrome p450-like protein 0.0069 0.0255 0.2152
Brugia malayi Thrombospondin N-terminal -like domain containing protein 0.0071 0.0262 0.0383
Plasmodium falciparum DNA topoisomerase 2 0.0062 0.0219 0.3666
Trichomonas vaginalis sugar transporter, putative 0.0019 0.0006 0.0029
Echinococcus multilocularis steroid dehydrogenase 0.0021 0.0013 0.0011
Echinococcus multilocularis oxidoreductase 0.0021 0.0013 0.0011
Mycobacterium tuberculosis Probable pyruvate kinase PykA 0.004 0.011 0.0273
Brugia malayi Nuclear hormone receptor family member nhr-31 0.026 0.1198 0.1763
Echinococcus multilocularis epidermal retinal dehydrogenase 2 0.0021 0.0013 0.0011
Echinococcus multilocularis subfamily M12B unassigned peptidase 0.0022 0.0018 0.0016
Trichomonas vaginalis sugar transporter, putative 0.0019 0.0006 0.0029
Trypanosoma cruzi oxidoreductase-like protein, putative 0.0021 0.0013 0.0114
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0245 0.1122 0.2839
Leishmania major protein kinase, putative 0.0068 0.0246 0.2081
Loa Loa (eye worm) hypothetical protein 0.0027 0.0046 0.0053
Plasmodium falciparum nitric oxide synthase, putative 0.0026 0.0039 0.062
Echinococcus granulosus jun protein 0.0083 0.0321 0.0319
Mycobacterium ulcerans aldehyde dehydrogenase 0.0194 0.087 0.2201
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD2 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0027 0.0046 0.0111
Echinococcus granulosus oxidoreductase 0.0021 0.0013 0.0011
Mycobacterium tuberculosis Probable cytochrome P450 138 Cyp138 0.0033 0.0074 0.0181
Schistosoma mansoni cytosol alanyl aminopeptidase (M01 family) 0.0232 0.1059 0.1059
Brugia malayi nuclear hormone receptor 0.0123 0.0518 0.076
Brugia malayi hypothetical protein 0.0023 0.0023 0.003
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.026 0.1198 0.1763
Loa Loa (eye worm) hypothetical protein 0.0869 0.4214 0.5089
Plasmodium falciparum ATP-dependent 6-phosphofructokinase 0.0035 0.0082 0.1354
Echinococcus multilocularis adam 0.0038 0.0098 0.0096
Echinococcus granulosus pyruvate kinase 0.0021 0.0013 0.0011
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0048 0.0149 0.0147
Loa Loa (eye worm) hypothetical protein 0.0019 0.0006 0.0005
Onchocerca volvulus Bile acid receptor homolog 0.026 0.1198 0.4302
Plasmodium vivax isocitrate dehydrogenase [NADP], mitochondrial, putative 0.0053 0.0172 0.2861
Brugia malayi Kazal-type serine protease inhibitor domain containing protein 0.0019 0.0003 0.0002
Loa Loa (eye worm) hypothetical protein 0.009 0.0355 0.0427
Loa Loa (eye worm) hypothetical protein 0.0138 0.0594 0.0715
Schistosoma mansoni carbonyl reductase 0.0021 0.0013 0.0013
Loa Loa (eye worm) peptidase family M13 containing protein 0.0602 0.2892 0.3491
Mycobacterium ulcerans beta-lactamase 0.0042 0.0117 0.029
Brugia malayi Sugar transporter family protein 0.0019 0.0006 0.0006
Mycobacterium ulcerans short chain dehydrogenase 0.0021 0.0013 0.0029
Onchocerca volvulus 0.0027 0.0046 0.0154
Brugia malayi hypothetical protein 0.0021 0.0013 0.0017
Echinococcus multilocularis cpg binding protein 0.0063 0.0221 0.0218
Plasmodium vivax M1-family alanyl aminopeptidase, putative 0.0138 0.0594 1
Mycobacterium ulcerans aldehyde dehydrogenase 0.0194 0.087 0.2201
Mycobacterium tuberculosis Probable cytochrome P450 123 Cyp123 0.0033 0.0074 0.0181
Schistosoma mansoni short chain dehydrogenase 0.0021 0.0013 0.0013
Loa Loa (eye worm) hypothetical protein 0.0602 0.2892 0.3491
Loa Loa (eye worm) hypothetical protein 0.0019 0.0003 0.0001
Trypanosoma brucei short-chain dehydrogenase, putative 0.0021 0.0013 0.0114
Echinococcus multilocularis DNA topoisomerase 2 alpha 0.0062 0.0219 0.0217
Onchocerca volvulus Pyruvate kinase homolog 0.004 0.011 0.0384
Trichomonas vaginalis conserved hypothetical protein 0.0019 0.0006 0.0029
Loa Loa (eye worm) hypothetical protein 0.0134 0.0575 0.0692
Brugia malayi Carboxylesterase family protein 0.0023 0.0023 0.003
Echinococcus multilocularis retinoic acid receptor rxr beta a retinoic acid receptor rxr alpha a retinoic acid receptor rxr alpha 0.0123 0.0518 0.0516
Onchocerca volvulus 0.0123 0.0518 0.1853
Schistosoma mansoni aryl hydrocarbon receptor 0.0259 0.1193 0.1193
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.0078 0.0297 0.0295
Echinococcus granulosus nuclear factor of activated T cells 5 0.0146 0.0631 0.0629
Mycobacterium ulcerans aminopeptidase N PepN 0.0232 0.1059 0.2681
Echinococcus multilocularis thioredoxin glutathione reductase 0.0038 0.01 0.0098
Schistosoma mansoni serine/threonine protein kinase 0.005 0.0159 0.0159
Echinococcus multilocularis mitogen activated protein kinase 3 0.005 0.0159 0.0157
Brugia malayi major facilitator superfamily protein 0.0019 0.0006 0.0006
Trichomonas vaginalis set domain proteins, putative 0.0287 0.1333 1
Echinococcus multilocularis GTP binding nuclear protein Ran 0.0021 0.0014 0.0012
Echinococcus multilocularis citrate lyase subunit beta protein 0.003 0.0057 0.0055
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0021 0.0013 0.0017
Schistosoma mansoni glutamine synthetase bacteria 0.0034 0.0079 0.0079
Loa Loa (eye worm) major facilitator superfamily transporter 0.0019 0.0006 0.0005
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0021 0.0013 0.0017
Mycobacterium ulcerans short-chain dehydrogenase 0.0021 0.0013 0.0029
Echinococcus granulosus cytochrome P450 2K1 0.0033 0.0074 0.0071
Loa Loa (eye worm) sugar transporter 0.0019 0.0006 0.0005
Mycobacterium ulcerans hypothetical protein 0.0027 0.0046 0.0111
Brugia malayi Importin beta-1 subunit 0.0029 0.0052 0.0073
Mycobacterium tuberculosis Probable cytochrome P450 132 Cyp132 0.0033 0.0074 0.0181
Echinococcus granulosus survival motor neuron protein 1 0.0467 0.2224 0.2223
Brugia malayi Thioredoxin reductase 0.0038 0.0097 0.014
Schistosoma mansoni steroid dehydrogenase 0.0021 0.0013 0.0013
Trypanosoma cruzi hypothetical protein, conserved 0.0257 0.1183 1
Loa Loa (eye worm) hypothetical protein 0.0071 0.0262 0.0314
Mycobacterium tuberculosis Possible cytochrome P450 135B1 Cyp135B1 0.0033 0.0074 0.0181
Brugia malayi latrophilin 2 splice variant baaae 0.0071 0.0264 0.0386
Trichomonas vaginalis sugar transporter, putative 0.0019 0.0006 0.0029
Mycobacterium leprae PROBABLE 6-PHOSPHOFRUCTOKINASE PFKA (PHOSPHOHEXOKINASE) (PHOSPHOFRUCTOKINASE) 0.0129 0.0547 0.1357
Schistosoma mansoni survival motor neuron protein 0.0095 0.0382 0.0382
Leishmania major quinonoid dihydropteridine reductase 0.0021 0.0013 0.0114
Trypanosoma cruzi PAS-domain containing phosphoglycerate kinase, putative 0.0067 0.0244 0.2062
Leishmania major short chain dehydrogenase-like protein 0.0021 0.0013 0.0114
Echinococcus multilocularis solute carrier family 22 0.0019 0.0006 0.0004
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.026 0.1198 0.1196
Mycobacterium ulcerans cytochrome P450 191A3 Cyp191A3 0.0033 0.0074 0.0181
Trichomonas vaginalis phosphofructokinase, putative 0.0129 0.0547 0.4092
Loa Loa (eye worm) short chain dehydrogenase/reductase family oxidoreductase 0.0021 0.0013 0.0014
Mycobacterium tuberculosis NADPH-dependent mycothiol reductase Mtr 0.0038 0.0097 0.0242
Mycobacterium ulcerans ketoacyl reductase 0.0021 0.0013 0.0029
Loa Loa (eye worm) steroid hormone receptor 0.026 0.1198 0.1444
Mycobacterium tuberculosis Probable oxidoreductase 0.0021 0.0013 0.0029
Loa Loa (eye worm) oxidoreductase 0.0021 0.0013 0.0014
Trypanosoma cruzi PAS-domain containing phosphoglycerate kinase, putative 0.0067 0.0244 0.2062
Schistosoma mansoni 6-phosphofructokinase 0.0129 0.0547 0.0547
Schistosoma mansoni intermediate filament proteins 0.017 0.0753 0.0753
Echinococcus granulosus pyruvate kinase 0.0021 0.0013 0.0011
Brugia malayi nuclear receptor NHR-67 0.0123 0.0518 0.076
Brugia malayi Bromodomain containing protein 0.0096 0.0387 0.0567
Entamoeba histolytica hypothetical protein, conserved 0.0021 0.0013 0.0081
Loa Loa (eye worm) hypothetical protein 0.0067 0.0244 0.0292
Trichomonas vaginalis sugar transporter, putative 0.0019 0.0006 0.0029
Leishmania major quinonoid dihydropteridine reductase 0.0021 0.0013 0.0114
Toxoplasma gondii histone lysine methyltransferase SET1 0.0117 0.0488 0.1231
Trypanosoma cruzi 3-keto-dihydrosphingosine reductase 0.0021 0.0013 0.0114
Brugia malayi hypothetical protein 0.0754 0.3642 0.5368
Trichomonas vaginalis D-aminoacylase, putative 0.0042 0.0117 0.0859
Echinococcus granulosus cpg binding protein 0.0063 0.0221 0.0218
Mycobacterium tuberculosis Cytochrome P450 121 Cyp121 0.0033 0.0074 0.0181
Brugia malayi Major Facilitator Superfamily protein 0.0019 0.0006 0.0006
Echinococcus multilocularis family S9 non peptidase ue (S09 family) 0.0023 0.0023 0.0021
Schistosoma mansoni steroid dehydrogenase 0.0021 0.0013 0.0013
Schistosoma mansoni ap endonuclease 0.0019 0.0002 0.0002
Loa Loa (eye worm) PHD-finger family protein 0.0024 0.0031 0.0035
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0021 0.0013 0.0029
Giardia lamblia Oxidoreductase, short chain dehydrogenase/reductase family 0.0021 0.0013 0.0554
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0037 0.0095 0.0095
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0021 0.0013 0.0029
Trypanosoma cruzi STE/STE11 serine/threonine-protein kinase, putative 0.0068 0.0246 0.2081
Leishmania major hypothetical protein, conserved 0.0021 0.0013 0.0114
Brugia malayi hypothetical protein 0.0027 0.0047 0.0065
Trypanosoma cruzi PAB1-binding protein , putative 0.003 0.0058 0.0491
Leishmania major pyruvate kinase 0.004 0.011 0.0929
Trichomonas vaginalis conserved hypothetical protein 0.0019 0.0006 0.0029
Plasmodium falciparum glutamine synthetase, putative 0.0087 0.034 0.5715
Trichomonas vaginalis sugar transporter, putative 0.0019 0.0006 0.0029
Trypanosoma cruzi short-chain dehydrogenase, putative 0.0021 0.0013 0.0114
Mycobacterium ulcerans short chain dehydrogenase 0.0021 0.0013 0.0029
Schistosoma mansoni neprilysin 0.0213 0.0963 0.0963
Trypanosoma brucei myo-inositol/proton symporter (MIT) 0.0019 0.0006 0.0051
Brugia malayi Retinol dehydrogenase 12 0.0021 0.0013 0.0017
Mycobacterium ulcerans short chain dehydrogenase 0.0021 0.0013 0.0029
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0044 0.013 0.0188
Loa Loa (eye worm) hypothetical protein 0.026 0.1198 0.1444
Loa Loa (eye worm) hypothetical protein 0.0019 0.0006 0.0005
Loa Loa (eye worm) cytochrome P450 family protein 0.0069 0.0255 0.0305
Trypanosoma cruzi target of rapamycin kinase 3 0.0035 0.0085 0.072
Mycobacterium ulcerans 3-alpha-hydroxysteroid dehydrogenase 0.0021 0.0013 0.0029
Trypanosoma brucei DNA topoisomerase II beta, putative 0.0056 0.0188 0.159
Schistosoma mansoni glutamine synthetase bacteria 0.0034 0.0079 0.0079
Chlamydia trachomatis pyruvate kinase 0.004 0.011 0.3993
Loa Loa (eye worm) hypothetical protein 0.002 0.0012 0.0012
Mycobacterium ulcerans short chain dehydrogenase 0.0021 0.0013 0.0029
Plasmodium vivax 6-phosphofructokinase, putative 0.0035 0.0082 0.1354
Brugia malayi hypothetical protein 0.0019 0.0006 0.0005
Schistosoma mansoni short chain dehydrogenase 0.0021 0.0013 0.0013
Trypanosoma cruzi hypothetical protein, conserved 0.0021 0.0013 0.0114
Schistosoma mansoni subfamily M12B unassigned peptidase (M12 family) 0.0022 0.0018 0.0018
Brugia malayi hypoxia-induced factor 1 0.0802 0.3881 0.5721
Loa Loa (eye worm) hypothetical protein 0.0019 0.0003 0.0001
Trichomonas vaginalis sugar transporter, putative 0.0019 0.0006 0.0029
Onchocerca volvulus DNA topoisomerase 2 homolog 0.0045 0.0134 0.0472
Echinococcus granulosus 6 phosphofructokinase 0.0129 0.0547 0.0545
Mycobacterium tuberculosis Fatty-acid-AMP ligase FadD30 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) 0.002 0.0012 0.0024
Echinococcus granulosus Dehydrogenase:reductase SDR family 0.0021 0.0013 0.0011
Onchocerca volvulus 0.0232 0.1059 0.3803
Echinococcus granulosus solute carrier family 22 0.0019 0.0006 0.0004
Trypanosoma cruzi pyruvate kinase 2, putative 0.004 0.011 0.0929
Trypanosoma brucei GTP-binding nuclear protein rtb2, putative 0.0021 0.0014 0.0122
Onchocerca volvulus 0.0021 0.0013 0.0037
Echinococcus multilocularis follistatin 0.0019 0.0003 0.0001
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0298 0.1387 0.1385
Trypanosoma cruzi pyruvate kinase 2, putative 0.004 0.011 0.0929
Loa Loa (eye worm) aminopeptidase N 0.0232 0.1059 0.1277
Echinococcus multilocularis Peptidase M1, membrane alanine aminopeptidase, N terminal 0.0232 0.1059 0.1057
Onchocerca volvulus 0.0019 0.0006 0.001
Echinococcus granulosus Nuclear hormone receptor HR96 0.0123 0.0518 0.0516
Leishmania major hypothetical protein, conserved 0.0019 0.0006 0.0051
Loa Loa (eye worm) oxidoreductase 0.0021 0.0013 0.0014
Trypanosoma cruzi hypothetical protein, conserved 0.0021 0.0013 0.0114
Loa Loa (eye worm) hypothetical protein 0.0071 0.0262 0.0314
Echinococcus multilocularis carbonyl reductase 1 0.0021 0.0013 0.0011
Echinococcus granulosus histone lysine methyltransferase setb 0.0057 0.0195 0.0193
Echinococcus multilocularis aminopeptidase N 0.0579 0.278 0.2778
Loa Loa (eye worm) MH2 domain-containing protein 0.0141 0.061 0.0734
Trichomonas vaginalis sugar transporter, putative 0.0019 0.0006 0.0029
Trichomonas vaginalis pyruvate kinase, putative 0.004 0.011 0.0809
Echinococcus multilocularis jun protein 0.0083 0.0321 0.0319
Schistosoma mansoni steroid dehydrogenase 0.0021 0.0013 0.0013
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0027 0.0046 0.0111
Chlamydia trachomatis DNA gyrase subunit B 0.0034 0.0078 0.2692
Schistosoma mansoni acetyl-CoA C-acetyltransferase 0.003 0.0059 0.0059
Schistosoma mansoni slit 0.0071 0.0262 0.0262
Onchocerca volvulus 0.0138 0.0594 0.2127
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0033 0.0074 0.0106
Mycobacterium ulcerans cytochrome P450 123A3 Cyp123A3 0.0033 0.0074 0.0181
Echinococcus multilocularis solute carrier family 2 facilitated glucose 0.0019 0.0006 0.0004
Mycobacterium ulcerans carveol-like dehydrogenase 0.0021 0.0013 0.0029
Trypanosoma brucei 3-keto-dihydrosphingosine reductase 0.0021 0.0013 0.0114
Mycobacterium leprae Conserved hypothetical protein 0.0033 0.0074 0.0153
Entamoeba histolytica pyrophosphate-dependent phosphofructokinase 0.0035 0.0082 0.0579
Trichomonas vaginalis sugar transporter, putative 0.0019 0.0006 0.0029
Brugia malayi isocitrate dehydrogenase 0.0053 0.0172 0.025
Echinococcus granulosus fetal alzheimer antigen falz 0.003 0.0059 0.0056
Mycobacterium tuberculosis Probable oxidoreductase 0.0096 0.0385 0.097
Trypanosoma brucei glucose transporter, putative 0.0019 0.0006 0.0051
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0042 0.0117 0.0117
Brugia malayi Kazal-type serine protease inhibitor domain containing protein 0.0019 0.0003 0.0002
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.026 0.1198 0.1444
Echinococcus multilocularis solute carrier family 2 facilitated glucose 0.0019 0.0006 0.0004
Loa Loa (eye worm) hypothetical protein 0.0081 0.031 0.0372
Plasmodium vivax thioredoxin reductase, putative 0.0038 0.0097 0.161
Mycobacterium ulcerans long-chain-fatty-acid-CoA ligase 0.0027 0.0046 0.0111
Entamoeba histolytica phosphofructokinase, putative 0.0129 0.0547 0.3933
Echinococcus multilocularis gcn5proteinral control of amino acid synthesis 0.0174 0.0773 0.0771
Leishmania major dehydrogenase-like protein 0.0021 0.0013 0.0114
Schistosoma mansoni 3-keto-dihydrosphingosine reductase 0.0021 0.0013 0.0013
Trichomonas vaginalis conserved hypothetical protein 0.0019 0.0006 0.0029
Loa Loa (eye worm) hypothetical protein 0.0049 0.0155 0.0185
Entamoeba histolytica hypothetical protein, conserved 0.0021 0.0013 0.0081
Echinococcus granulosus hypothetical protein 0.0021 0.0013 0.0011
Loa Loa (eye worm) hypothetical protein 0.0404 0.1909 0.2304
Brugia malayi AMP-binding enzyme family protein 0.0027 0.0046 0.0065
Schistosoma mansoni adam (A disintegrin and metalloprotease 0.0038 0.0098 0.0098
Mycobacterium ulcerans citrate (pro-3S)-lyase subunit beta 0.003 0.0057 0.0139
Brugia malayi Steroid receptor seven-up type 2 0.026 0.1198 0.1763
Loa Loa (eye worm) hypothetical protein 0.0027 0.0047 0.0054
Schistosoma mansoni thyroid hormone receptor 0.026 0.1198 0.1198
Onchocerca volvulus 0.0019 0.0006 0.001
Mycobacterium ulcerans short chain dehydrogenase 0.0021 0.0013 0.0029
Schistosoma mansoni DNA topoisomerase II 0.0062 0.0219 0.0219
Loa Loa (eye worm) tyrosinase 1 0.009 0.0355 0.0427
Brugia malayi Calcitonin receptor-like protein seb-1 0.0104 0.0428 0.0627
Onchocerca volvulus 0.0049 0.0155 0.0546
Toxoplasma gondii target of rapamycin (TOR), putative 0.0033 0.0074 0.0181
Trichomonas vaginalis phosphofructokinase, putative 0.0129 0.0547 0.4092
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0021 0.0013 0.0017
Echinococcus multilocularis acetylcholinesterase 0.0134 0.0575 0.0573
Plasmodium vivax hypothetical protein, conserved 0.0021 0.0013 0.019
Toxoplasma gondii oxidoreductase, short chain dehydrogenase/reductase family protein 0.0021 0.0013 0.0029
Echinococcus granulosus carbonyl reductase 1 0.0021 0.0013 0.0011
Loa Loa (eye worm) hypothetical protein 0.0123 0.0518 0.0623
Echinococcus granulosus 3 ketodihydrosphingosine reductase 0.0021 0.0013 0.0011
Echinococcus multilocularis Ankyrin 0.0029 0.0052 0.005
Leishmania major hypothetical protein, conserved 0.0021 0.0013 0.0114
Brugia malayi Angiotensin-converting enzyme family protein 0.1388 0.6782 1
Schistosoma mansoni dihydroceramide desaturase 0.0022 0.0018 0.0018
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0042 0.0117 0.0138
Echinococcus multilocularis organic anion transporting polypeptide 30B 0.0027 0.0047 0.0044
Echinococcus multilocularis nuclear receptor nhr 48 0.0123 0.0518 0.0516
Loa Loa (eye worm) sodium-independent organic anion transporter 0.0027 0.0047 0.0054
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.026 0.1198 0.1444
Trichomonas vaginalis sugar transporter, putative 0.0019 0.0006 0.0029
Brugia malayi hypothetical protein 0.0467 0.2224 0.3278
Trichomonas vaginalis sugar transporter, putative 0.0019 0.0006 0.0029
Brugia malayi Cytochrome P450 family protein 0.0113 0.0468 0.0686
Loa Loa (eye worm) hypothetical protein 0.0021 0.0013 0.0014
Echinococcus granulosus Sugar transporter ERD6 protein 0.0019 0.0006 0.0004
Trypanosoma cruzi hexose transporter, putative 0.0019 0.0006 0.0051
Echinococcus granulosus snurportin 1 0.0305 0.142 0.1418
Brugia malayi cytoplasmic intermediate filament protein 0.0091 0.0362 0.053
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0021 0.0013 0.0017
Brugia malayi hypothetical protein 0.0038 0.0098 0.0142
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.0042 0.0117 0.029
Loa Loa (eye worm) hypothetical protein 0.0616 0.2962 0.3576
Loa Loa (eye worm) hypothetical protein 0.0027 0.0047 0.0054
Brugia malayi phosphofructokinase 0.0129 0.0547 0.0803
Echinococcus granulosus retinoic acid receptor rxr beta a 0.026 0.1198 0.1196
Trichomonas vaginalis short-chain dehydrogenase, putative 0.0021 0.0013 0.0085
Schistosoma mansoni family M13 non-peptidase homologue (M13 family) 0.0411 0.1946 0.1946
Mycobacterium ulcerans integral membrane transport protein 0.0019 0.0006 0.001
Mycobacterium ulcerans hypothetical protein 0.003 0.0057 0.0139
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0123 0.0518 0.1853
Leishmania major short chain dehydrogenase/reductase, putative 0.0021 0.0013 0.0114
Echinococcus granulosus aminopeptidase N 0.0579 0.278 0.2778
Echinococcus granulosus carbonyl reductase 1 0.0021 0.0013 0.0011
Loa Loa (eye worm) hypothetical protein 0.0037 0.0091 0.0108
Schistosoma mansoni hypothetical protein 0.0033 0.0074 0.0074
Plasmodium falciparum isocitrate dehydrogenase [NADP], mitochondrial 0.0053 0.0172 0.2861
Leishmania major pteridine reductase 1 0.0021 0.0013 0.0114
Schistosoma mansoni endothelin-converting enzyme-like 1 (damage-induced neuronal endopeptidase) 0.0198 0.0893 0.0893
Schistosoma mansoni RAR-like nuclear receptor 0.026 0.1198 0.1198
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0048 0.0149 0.0217
Trypanosoma cruzi 3-ketoacyl-CoA reductase, putative 0.0021 0.0013 0.0114
Mycobacterium ulcerans cytochrome p450 150 cyp150 0.0033 0.0074 0.0181
Echinococcus multilocularis endothelin converting enzyme 1 0.0815 0.3945 0.3943
Echinococcus multilocularis solute carrier family 22 0.0019 0.0006 0.0004
Trypanosoma cruzi glucose transporter, putative 0.0019 0.0006 0.0051
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD7 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0019 0.0006 0.001
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0021 0.0013 0.0017
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0021 0.0013 0.0017
Onchocerca volvulus Netrin receptor homolog 0.0028 0.0051 0.0172
Trichomonas vaginalis sugar transporter, putative 0.0019 0.0006 0.0029
Loa Loa (eye worm) kazal-type serine protease inhibitor domain-containing protein 0.0019 0.0003 0.0001
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.0042 0.0117 0.029
Trypanosoma brucei short-chain dehydrogenase, putative 0.0021 0.0013 0.0114
Trypanosoma brucei glucose transporter, putative 0.0019 0.0006 0.0051
Echinococcus multilocularis geminin 0.0733 0.3538 0.3537
Onchocerca volvulus 0.0021 0.0013 0.0037
Trichomonas vaginalis sulfite reductase, putative 0.0026 0.0039 0.0276
Brugia malayi Hypothetical zinc metalloproteinase T16A9.4 0.0815 0.3945 0.5815
Plasmodium falciparum importin beta, putative 0.0029 0.0052 0.0838
Brugia malayi F/Y-rich N-terminus family protein 0.0021 0.0015 0.0018
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0037 0.0095 0.0093
Mycobacterium ulcerans short chain dehydrogenase 0.0021 0.0013 0.0029
Entamoeba histolytica FKBP-rapamycin associated protein (FRAP), putative 0.0044 0.013 0.0921
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.026 0.1198 0.1196
Loa Loa (eye worm) dehydrogenase 0.0021 0.0013 0.0014
Echinococcus granulosus puromycin sensitive aminopeptidase 0.0232 0.1059 0.1057
Leishmania major mitogen activated protein kinase, putative,map kinase, putative 0.005 0.0159 0.1346
Mycobacterium tuberculosis Possible fatty acyl-CoA reductase 0.0021 0.0013 0.0029
Loa Loa (eye worm) CXXC zinc finger family protein 0.0057 0.0193 0.0231
Brugia malayi nuclear receptor NHR-88 0.026 0.1198 0.1763
Trichomonas vaginalis sugar transporter, putative 0.0019 0.0006 0.0029
Loa Loa (eye worm) hypothetical protein 0.0123 0.0518 0.0623
Mycobacterium tuberculosis Probable 6-phosphofructokinase PfkA (phosphohexokinase) (phosphofructokinase) 0.0129 0.0547 0.1382
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0053 0.0172 0.0169
Trypanosoma brucei isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0053 0.0172 0.145
Schistosoma mansoni cpg binding protein 0.0063 0.0221 0.0221
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0021 0.0013 0.0017
Leishmania major 2,4-dihydroxyhept-2-ene-1,7-dioic acid aldolase, putative 0.003 0.0057 0.0481
Plasmodium falciparum hexose transporter 0.0019 0.0006 0.0065
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0028 0.0051 0.0059
Echinococcus multilocularis ecdysone induced protein 78C 0.026 0.1198 0.1196
Loa Loa (eye worm) hypothetical protein 0.002 0.0007 0.0006
Leishmania major quinonoid dihydropteridine reductase 0.0021 0.0013 0.0114
Echinococcus granulosus hypothetical protein 0.0021 0.0013 0.0011
Trypanosoma cruzi trypanothione reductase, putative 0.0038 0.0097 0.0824
Loa Loa (eye worm) TATA binding protein associated factor 0.0138 0.0594 0.0715
Brugia malayi sodium-independent organic anion transporter family protein 0.0027 0.0047 0.0065
Brugia malayi dehydrogenases, short chain protein 9 0.0021 0.0013 0.0017
Echinococcus multilocularis NADPH dependent diflavin oxidoreductase 1 0.0026 0.0039 0.0037
Echinococcus multilocularis beta LACTamase domain containing family member 0.0042 0.0117 0.0114
Trichomonas vaginalis glucose transporter, putative 0.0019 0.0006 0.0029
Mycobacterium ulcerans short chain dehydrogenase 0.0021 0.0013 0.0029
Mycobacterium ulcerans dehydrogenase/decarboxylase protein 0.0021 0.0013 0.0029
Schistosoma mansoni family M13 unassigned peptidase (M13 family) 0.0198 0.0893 0.0893
Echinococcus multilocularis puromycin sensitive aminopeptidase 0.0232 0.1059 0.1057
Toxoplasma gondii oxidoreductase, putative 0.0021 0.0013 0.0029
Mycobacterium tuberculosis Probable dehydrogenase 0.0086 0.0337 0.085
Loa Loa (eye worm) oxidoreductase 0.0021 0.0013 0.0014
Giardia lamblia Reductase, putative 0.0021 0.0013 0.0554
Schistosoma mansoni hypothetical protein 0.0019 0.0006 0.0006
Mycobacterium tuberculosis Probable chain -fatty-acid-CoA ligase FadD13 (fatty-acyl-CoA synthetase) 0.0027 0.0046 0.0111
Brugia malayi D-beta-hydroxybutyrate dehydrogenase, mitochondrial precursor 0.0021 0.0013 0.0017
Giardia lamblia Short-chain dehydrogenase, putative 0.0021 0.0013 0.0554
Echinococcus multilocularis solute carrier family 2 facilitated glucose 0.0019 0.0006 0.0004
Echinococcus multilocularis isocitrate dehydrogenase 2 (NADP+) 0.0053 0.0172 0.0169
Onchocerca volvulus 0.0019 0.0006 0.001
Plasmodium vivax sugar transporter, putative 0.0019 0.0006 0.0065
Schistosoma mansoni jun-related protein 0.0067 0.0244 0.0244
Plasmodium vivax GTP-binding nuclear protein RAN/TC4, putative 0.0021 0.0014 0.0207
Brugia malayi dehydrogenases, short chain protein 2 0.0021 0.0013 0.0017
Mycobacterium ulcerans hypothetical protein 0.0042 0.0117 0.029
Mycobacterium tuberculosis Probable short-chain type dehydrogenase/reductase 0.0021 0.0013 0.0029
Entamoeba histolytica hypothetical protein 0.0298 0.1387 1
Brugia malayi hypothetical protein 0.0137 0.059 0.0868
Trichomonas vaginalis short-chain dehydrogenases/reductase, putative 0.0021 0.0013 0.0085
Echinococcus multilocularis transient receptor potential cation channel 0.0021 0.0013 0.0011
Schistosoma mansoni Tr4/Tr2 (homologue) 0.026 0.1198 0.1198
Trichomonas vaginalis PIKK family atypical protein kinase 0.0024 0.0029 0.0199
Trypanosoma brucei phosphatidylinositol 3-kinase tor, putative 0.0021 0.0014 0.012
Toxoplasma gondii Kazal-type serine protease inhibitor domain-containing protein 0.0019 0.0003 0.0003
Schistosoma mansoni short chain dehydrogenase 0.0021 0.0013 0.0013
Loa Loa (eye worm) D-ets-4 DNA binding domain-containing protein 0.0072 0.0266 0.0318
Toxoplasma gondii isocitrate dehydrogenase 0.0053 0.0172 0.0429
Mycobacterium tuberculosis Cytochrome P450 51 Cyp51 (CYPL1) (P450-L1A1) (sterol 14-alpha demethylase) (lanosterol 14-alpha demethylase) (P450-14DM) 0.0033 0.0074 0.0181
Loa Loa (eye worm) hypothetical protein 0.0123 0.0518 0.0623
Loa Loa (eye worm) angiotensin-converting enzyme family protein 0.1388 0.6782 0.8191
Loa Loa (eye worm) hypothetical protein 0.0019 0.0006 0.0005
Plasmodium vivax glutathione reductase, putative 0.0038 0.0097 0.161
Schistosoma mansoni Nep2 peptidase (M13 family) 0.0411 0.1946 0.1946
Schistosoma mansoni aldehyde dehydrogenase 0.0194 0.087 0.087
Loa Loa (eye worm) fli-1 protein 0.0218 0.0989 0.1192
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.026 0.1198 0.1444
Brugia malayi EGF-like domain containing protein 0.0071 0.0262 0.0383
Echinococcus multilocularis adam 17 protease 0.0218 0.0991 0.0989
Echinococcus multilocularis cytoplasmic intermediate filament protein 0.0082 0.0317 0.0315
Trypanosoma brucei metallo-peptidase, Clan MA(E) Family M1 0.0232 0.1059 0.8957
Trichomonas vaginalis hydroxyacyl dehydrogenase, putative 0.0021 0.0013 0.0085
Loa Loa (eye worm) peptidase family M13 containing protein 0.0602 0.2892 0.3491
Mycobacterium ulcerans cytochrome P450 144A4 Cyp144A4 0.0033 0.0074 0.0181
Schistosoma mansoni cpg binding protein 0.0057 0.0193 0.0193
Schistosoma mansoni steroid dehydrogenase 0.0021 0.0013 0.0013
Loa Loa (eye worm) hypothetical protein 0.0022 0.0018 0.0019
Entamoeba histolytica estradiol 17-beta-dehydrogenase, putative 0.0021 0.0013 0.0081
Schistosoma mansoni cytochrome P450 0.0033 0.0074 0.0074
Echinococcus multilocularis para nitrobenzyl esterase 0.0023 0.0023 0.0021
Echinococcus multilocularis 0.0033 0.0074 0.0071
Loa Loa (eye worm) hypothetical protein 0.0045 0.0135 0.0161
Leishmania major 3-oxoacyl-(acyl-carrier protein) reductase, putative 0.0245 0.1122 0.9483
Loa Loa (eye worm) hypothetical protein 0.0123 0.0518 0.0623
Mycobacterium ulcerans glutamine synthetase GlnA1 0.0087 0.034 0.0858
Loa Loa (eye worm) hypothetical protein 0.0094 0.0376 0.0451
Loa Loa (eye worm) 3-hydroxyacyl-CoA dehydrogenase type II 0.0224 0.1018 0.1228
Loa Loa (eye worm) phosphatidylinositol 3 0.0044 0.013 0.0154
Mycobacterium tuberculosis Probable oxidoreductase 0.0021 0.0013 0.0029
Mycobacterium ulcerans esterase/lipase LipP 0.0042 0.0117 0.029
Mycobacterium tuberculosis Conserved protein 0.003 0.0057 0.0139
Trichomonas vaginalis importin beta-1, putative 0.0023 0.0025 0.0172
Giardia lamblia Sugar-proton symporter 0.0019 0.0006 0.0189
Trichomonas vaginalis conserved hypothetical protein 0.0019 0.0006 0.0029
Trichomonas vaginalis ran, putative 0.0021 0.0014 0.0092
Onchocerca volvulus 0.0021 0.0013 0.0037
Trypanosoma brucei importin beta-1 subunit, putative 0.0029 0.0052 0.0438
Trichomonas vaginalis sugar transporter, putative 0.0019 0.0006 0.0029
Loa Loa (eye worm) acetyltransferase 0.0174 0.0773 0.0931
Mycobacterium tuberculosis Possible exported protein 0.0591 0.2836 0.7188
Echinococcus granulosus zinc finger protein 0.0031 0.0062 0.006
Schistosoma mansoni hypothetical protein 0.0028 0.0051 0.0051
Brugia malayi Fli-1 protein 0.0218 0.0989 0.1455
Trichomonas vaginalis phosphofructokinase, putative 0.0035 0.0082 0.0602
Trypanosoma brucei target of rapamycin kinase 3, putative 0.0035 0.0085 0.072
Entamoeba histolytica acetyltransferase, GNAT family 0.0046 0.0139 0.0989
Echinococcus multilocularis carbonyl reductase 1 0.0021 0.0013 0.0011
Trichomonas vaginalis Citrate lyase beta chain, putative 0.003 0.0057 0.0411
Trypanosoma brucei mitogen activated protein kinase 4, putative 0.005 0.0159 0.1346
Brugia malayi conserved hypotetical protein 0.0123 0.0518 0.076
Trichomonas vaginalis PIKK family atypical protein kinase 0.0033 0.0074 0.0536
Trypanosoma cruzi hypothetical protein, conserved 0.0042 0.0117 0.0986
Echinococcus multilocularis expressed protein 0.0019 0.0003 0.0001
Echinococcus granulosus pikachurin 0.0071 0.0262 0.026
Echinococcus granulosus netrin receptor unc 5 0.0028 0.0051 0.0049
Mycobacterium tuberculosis Conserved protein 0.0042 0.0117 0.029
Brugia malayi nuclear receptor subfamily 1, group D, member 1, putative 0.0123 0.0518 0.076
Mycobacterium tuberculosis Probable cytochrome P450 128 Cyp128 0.0033 0.0074 0.0181
Echinococcus granulosus a disintegrin and metalloproteinase with 0.0103 0.0421 0.0419
Echinococcus multilocularis agrin 0.0019 0.0003 0.0001
Loa Loa (eye worm) hypothetical protein 0.0123 0.0518 0.0623
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.026 0.1198 0.1196
Schistosoma mansoni hypothetical protein 0.0033 0.0074 0.0074
Echinococcus multilocularis Solute carrier organic anion transporter family 0.0027 0.0047 0.0044
Trypanosoma cruzi cytochrome P450 reductase, putative 0.0026 0.0039 0.0329
Trypanosoma brucei oxidoreductase-like protein 0.0021 0.0013 0.0114
Schistosoma mansoni 3-hydroxyacyl-CoA dehydrogenase 0.0245 0.1122 0.1122
Brugia malayi Major Facilitator Superfamily protein 0.0019 0.0006 0.0006
Giardia lamblia Pyruvate kinase 0.004 0.011 0.5297
Trichomonas vaginalis guanylate cyclase, putative 0.0067 0.0244 0.1815
Trypanosoma cruzi metallo-peptidase, clan MA(E), family M1, putative 0.0232 0.1059 0.8957
Echinococcus multilocularis transfer RNA-Lys 0.0192 0.086 0.0858
Plasmodium falciparum GTP-binding nuclear protein RAN/TC4 0.0021 0.0014 0.0207
Brugia malayi Cytochrome P450 family protein 0.0033 0.0074 0.0105
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.026 0.1198 0.1198
Trichomonas vaginalis phosphofructokinase, putative 0.0129 0.0547 0.4092
Loa Loa (eye worm) hypothetical protein 0.0027 0.0047 0.0054
Loa Loa (eye worm) oxidoreductase 0.0021 0.0013 0.0014
Echinococcus granulosus pyruvate kinase 0.0021 0.0013 0.0011
Plasmodium vivax pyruvate kinase 2, putative 0.0021 0.0013 0.0179
Entamoeba histolytica glutamine synthetase, putative 0.0034 0.0079 0.0555
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0033 0.0074 0.0072
Echinococcus granulosus tumor protein p63 0.0337 0.1581 0.158
Onchocerca volvulus 0.0019 0.0006 0.001
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0021 0.0013 0.0017
Schistosoma mansoni family M13 unassigned peptidase (M13 family) 0.0213 0.0963 0.0963
Onchocerca volvulus 0.026 0.1198 0.4302
Schistosoma mansoni family M13 non-peptidase homologue (M13 family) 0.0198 0.0893 0.0893
Mycobacterium ulcerans ketoacyl reductase 0.0021 0.0013 0.0029
Mycobacterium tuberculosis Probable dehydrogenase/reductase 0.0021 0.0013 0.0029
Entamoeba histolytica DNA topoisomerase II, putative 0.0062 0.0219 0.1567
Schistosoma mansoni hypothetical protein 0.0067 0.0244 0.0244
Entamoeba histolytica acyl-CoA synthetase, putative 0.0027 0.0046 0.0317
Brugia malayi Nuclear hormone receptor E75 0.0123 0.0518 0.076
Loa Loa (eye worm) hypothetical protein 0.0027 0.0047 0.0054
Brugia malayi Hypothetical tyrosinase-like protein F21C3.2 in chromosome I 0.009 0.0355 0.0521
Schistosoma mansoni family M1 non-peptidase homologue (M01 family) 0.0094 0.0376 0.0376
Loa Loa (eye worm) hypothetical protein 0.0023 0.0023 0.0025
Loa Loa (eye worm) hypothetical protein 0.0123 0.0518 0.0623
Onchocerca volvulus 0.0021 0.0013 0.0037
Schistosoma mansoni pyruvate kinase 0.004 0.011 0.011
Brugia malayi Nuclear hormone receptor family member nhr-49 0.026 0.1198 0.1763
Echinococcus multilocularis musashi 0.017 0.0753 0.0751
Loa Loa (eye worm) hypothetical protein 0.026 0.1198 0.1444
Echinococcus granulosus histone acetyltransferase KAT2B 0.0167 0.0735 0.0733
Loa Loa (eye worm) hypothetical protein 0.0023 0.0023 0.0025
Echinococcus granulosus retinol dehydrogenase 11 0.0021 0.0013 0.0011
Mycobacterium ulcerans short chain dehydrogenase 0.0021 0.0013 0.0029
Trypanosoma brucei glucose transporter, putative 0.0019 0.0006 0.0051
Echinococcus multilocularis neurogenic locus notch protein 0.0071 0.0262 0.026
Trichomonas vaginalis sugar transporter, putative 0.0019 0.0006 0.0029
Schistosoma mansoni transcription factor LCR-F1 0.0298 0.1387 0.1387
Brugia malayi Sugar transporter family protein 0.0019 0.0006 0.0006
Loa Loa (eye worm) nuclear hormone receptor 0.0123 0.0518 0.0623
Leishmania major pyruvate kinase 0.004 0.011 0.0929
Loa Loa (eye worm) hypothetical protein 0.0023 0.0023 0.0025
Schistosoma mansoni leukotriene A4 hydrolase (M01 family) 0.169 0.8279 0.8279
Schistosoma mansoni steroid hormone receptor ad4bp 0.026 0.1198 0.1198
Schistosoma mansoni short chain dehydrogenase 0.0021 0.0013 0.0013
Trichomonas vaginalis sugar transporter, putative 0.0019 0.0006 0.0029
Schistosoma mansoni family M13 unassigned peptidase (M13 family) 0.0411 0.1946 0.1946
Plasmodium vivax M1-family alanyl aminopeptidase, putative 0.0138 0.0594 1
Entamoeba histolytica hypothetical protein 0.0023 0.0025 0.0165
Plasmodium falciparum M1-family alanyl aminopeptidase 0.0138 0.0594 1
Loa Loa (eye worm) hypothetical protein 0.0602 0.2892 0.3491
Treponema pallidum DNA gyrase, subunit B (gyrB) 0.0021 0.0012 0.018
Toxoplasma gondii aminopeptidase N protein 0.0138 0.0594 0.1501
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription factor 0.0083 0.0321 0.0319
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.005 0.0159 0.1346
Mycobacterium ulcerans DNA gyrase subunit B 0.0021 0.0012 0.0025
Trichomonas vaginalis adenylate and guanylate cyclases, putative 0.0067 0.0244 0.1815
Trichomonas vaginalis sugar transporter, putative 0.0019 0.0006 0.0029
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.0019 0.0002 0.0019
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0123 0.0518 0.1853
Loa Loa (eye worm) hypothetical protein 0.0028 0.0047 0.0054
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.026 0.1198 0.1198
Chlamydia trachomatis fructose-6-phosphate phosphotransferase 0.0035 0.0082 0.2871
Trichomonas vaginalis Clan MA, family M1, aminopeptidase N-like metallopeptidase 0.0232 0.1059 0.7942
Echinococcus granulosus lamin dm0 0.017 0.0753 0.0751
Echinococcus granulosus solute carrier family 22 0.0019 0.0006 0.0004
Trypanosoma cruzi Phosphatidylinositol 3-kinase tor1 0.0044 0.013 0.1098
Brugia malayi Cytochrome P450 family protein 0.0069 0.0255 0.0372
Brugia malayi ecdysteroid receptor 0.026 0.1198 0.1763
Onchocerca volvulus 0.0019 0.0006 0.001
Trypanosoma cruzi NAD(P)-dependent oxidoreductase, putative 0.0021 0.0013 0.0114
Trichomonas vaginalis sugar transporter, putative 0.0019 0.0006 0.0029
Mycobacterium ulcerans glutamine synthetase 0.0087 0.034 0.0858
Trypanosoma cruzi glutamine synthetase, putative 0.0135 0.0579 0.4895
Leishmania major 3-keto-dihydrosphingosine reductase 0.0021 0.0013 0.0114
Mycobacterium ulcerans cytochrome P450 108B4 Cyp108B4 0.0033 0.0074 0.0181
Trypanosoma brucei aminopeptidase, putative 0.0138 0.0594 0.5022
Entamoeba histolytica pyruvate kinase, putative 0.0028 0.005 0.0342
Schistosoma mansoni methyl-cpg binding protein mbd 0.002 0.001 0.001
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0033 0.0074 0.0072
Loa Loa (eye worm) hypothetical protein 0.0019 0.0006 0.0005
Trichomonas vaginalis guanylate cyclase, putative 0.0067 0.0244 0.1815
Echinococcus granulosus puromycin sensitive aminopeptidase 0.0232 0.1059 0.1057
Mycobacterium tuberculosis Probable short-chain type dehydrogenase/reductase 0.0021 0.0013 0.0029
Toxoplasma gondii aminopeptidase N, putative 0.0138 0.0594 0.1501
Loa Loa (eye worm) carboxylesterase 0.0023 0.0023 0.0025
Loa Loa (eye worm) nuclear hormone receptor-like 1 0.0137 0.059 0.0711
Echinococcus granulosus steroid dehydrogenase 0.0021 0.0013 0.0011
Mycobacterium tuberculosis Probable NADH dehydrogenase Ndh 0.0086 0.0337 0.085
Loa Loa (eye worm) CYP4Cod1 0.0069 0.0255 0.0305
Loa Loa (eye worm) hypothetical protein 0.0019 0.0003 0.0001
Brugia malayi Bromodomain containing protein 0.0049 0.0155 0.0226
Loa Loa (eye worm) cytochrome P450 0.0033 0.0074 0.0086
Mycobacterium tuberculosis Probable esterase LipL 0.0042 0.0117 0.029
Onchocerca volvulus 0.0023 0.0023 0.007
Trichomonas vaginalis D-aminoacylase, putative 0.0042 0.0117 0.0859
Loa Loa (eye worm) hypothetical protein 0.0079 0.0302 0.0362
Trypanosoma cruzi short chain dehydrogenase, putative 0.0021 0.0013 0.0114
Echinococcus granulosus solute carrier family 22 0.0019 0.0006 0.0004
Trypanosoma cruzi sugar transporter, putative 0.0019 0.0006 0.0051
Toxoplasma gondii cytochrome p450 superfamily protein 0.0033 0.0074 0.0181
Mycobacterium tuberculosis Probable cytochrome P450 monooxygenase 142 Cyp142 0.0033 0.0074 0.0181
Loa Loa (eye worm) hypothetical protein 0.0167 0.0738 0.0889
Brugia malayi glutathione reductase 0.0038 0.0097 0.014
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0057 0.0195 0.0193
Onchocerca volvulus 0.0067 0.0244 0.0866
Mycobacterium ulcerans cytochrome P450 136A2 Cyp136A2 0.0033 0.0074 0.0181
Trichomonas vaginalis adenylate and guanylate cyclases, putative 0.0067 0.0244 0.1815
Leishmania major hypothetical protein, conserved 0.0021 0.0013 0.0114
Trichomonas vaginalis sugar transporter, putative 0.0019 0.0006 0.0029
Schistosoma mansoni hypothetical protein 0.0305 0.142 0.142
Loa Loa (eye worm) agrin synaptic family protein 0.0019 0.0003 0.0001
Loa Loa (eye worm) hypothetical protein 0.0616 0.2962 0.3576
Schistosoma mansoni short chain dehydrogenase 0.0021 0.0013 0.0013
Echinococcus multilocularis pyruvate kinase 0.004 0.011 0.0108
Loa Loa (eye worm) 6-phosphofructokinase 0.0129 0.0547 0.0658
Toxoplasma gondii 6-phosphofructokinase 0.0035 0.0082 0.0203
Brugia malayi bZIP transcription factor family protein 0.0083 0.0321 0.0471
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0298 0.1387 0.1385
Loa Loa (eye worm) hypothetical protein 0.002 0.0012 0.0012
Onchocerca volvulus 0.0042 0.0117 0.0408
Brugia malayi hypothetical protein 0.0123 0.0518 0.076
Brugia malayi Protein kinase domain containing protein 0.0029 0.0053 0.0075
Echinococcus granulosus Basic leucine zipper bZIP transcription factor 0.0083 0.0321 0.0319
Brugia malayi laminin-like protein K08C7.3 precursor 0.0071 0.0262 0.0383
Leishmania major glucose transporter, lmgt2 0.0019 0.0006 0.0051
Toxoplasma gondii aminopeptidase n, putative 0.0138 0.0594 0.1501
Loa Loa (eye worm) hypothetical protein 0.0137 0.059 0.0711
Plasmodium falciparum major facilitator superfamily domain-containing protein, putative 0.0019 0.0006 0.0065
Trichomonas vaginalis short-chain dehydrogenase, putative 0.0021 0.0013 0.0085
Echinococcus multilocularis fetal alzheimer antigen, falz 0.003 0.0059 0.0056
Brugia malayi hypothetical protein 0.0019 0.0006 0.0006
Trichomonas vaginalis conserved hypothetical protein 0.0067 0.0244 0.1815
Toxoplasma gondii oxidoreductase, short chain dehydrogenase/reductase family protein 0.0021 0.0013 0.0029
Trypanosoma cruzi short chain dehydrogenase, putative 0.0021 0.0013 0.0114
Brugia malayi Nuclear hormone receptor family member nhr-41 0.026 0.1198 0.1763
Toxoplasma gondii oxidoreductase, short chain dehydrogenase/reductase family protein 0.0021 0.0013 0.0029
Onchocerca volvulus Pyruvate kinase homolog 0.004 0.011 0.0384
Trichomonas vaginalis short-chain dehydrogenase, putative 0.0021 0.0013 0.0085
Onchocerca volvulus 0.0019 0.0006 0.001
Echinococcus granulosus solute carrier family 2 facilitated glucose 0.0019 0.0006 0.0004
Echinococcus granulosus carbonyl reductase 1 0.0021 0.0013 0.0011
Brugia malayi Peptidase family M1 containing protein 0.0232 0.1059 0.1559
Schistosoma mansoni gabp alpha 0.0072 0.0266 0.0266
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD2 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0027 0.0046 0.0083
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0021 0.0013 0.0017
Schistosoma mansoni tyrosinase precursor 0.009 0.0355 0.0355
Loa Loa (eye worm) hypothetical protein 0.0019 0.0006 0.0005
Loa Loa (eye worm) hypothetical protein 0.0052 0.017 0.0202
Giardia lamblia GTP-binding nuclear protein RAN/TC4 0.0021 0.0014 0.0603
Onchocerca volvulus Putative DNA topoisomerase 2, mitochondrial 0.0045 0.0134 0.0472
Mycobacterium tuberculosis Possible oxidoreductase 0.0021 0.0013 0.0029
Entamoeba histolytica phosphofructokinase, putative 0.0129 0.0547 0.3933
Onchocerca volvulus 0.0029 0.0053 0.018
Trichomonas vaginalis DNA topoisomerase II, putative 0.0062 0.0219 0.163
Mycobacterium tuberculosis Probable glutamine synthetase GlnA2 (glutamine synthase) (GS-II) 0.0087 0.034 0.0858
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.005 0.0159 0.1346
Giardia lamblia Hexose transporter 0.0019 0.0006 0.0189
Echinococcus granulosus histone acetyltransferase KAT2B 0.0053 0.0174 0.0172
Mycobacterium ulcerans sugar transporter 0.0019 0.0006 0.001
Loa Loa (eye worm) CMGC/MAPK/ERK1 protein kinase 0.005 0.0159 0.019
Trichomonas vaginalis PIKK family atypical protein kinase 0.0033 0.0074 0.0536
Toxoplasma gondii DNA topoisomerase 2, putative 0.0062 0.0219 0.055
Loa Loa (eye worm) hypothetical protein 0.0082 0.0317 0.038
Echinococcus multilocularis steroid dehydrogenase 0.0021 0.0013 0.0011
Schistosoma mansoni protein tyrosine phosphatase non-receptor type nt1 0.0379 0.1788 0.1788
Plasmodium falciparum oxidoreductase, short-chain dehydrogenase family, putative 0.0021 0.0013 0.019
Schistosoma mansoni family M13 unassigned peptidase (M13 family) 0.0198 0.0893 0.0893
Loa Loa (eye worm) beta-lactamase 0.0042 0.0117 0.0138
Loa Loa (eye worm) hypothetical protein 0.0021 0.0013 0.0014
Echinococcus multilocularis conserved hypothetical protein 0.0021 0.0013 0.0011
Echinococcus multilocularis BC026374 protein (S09 family) 0.0023 0.0023 0.0021
Trichomonas vaginalis PIKK family atypical protein kinase 0.0026 0.004 0.0285
Brugia malayi Nuclear hormone receptor family member nhr-40 0.026 0.1198 0.1763
Loa Loa (eye worm) hypothetical protein 0.004 0.011 0.013
Loa Loa (eye worm) Gln-2 protein 0.0087 0.034 0.0409
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0021 0.0013 0.0017
Echinococcus granulosus thioredoxin glutathione reductase 0.0038 0.01 0.0098
Toxoplasma gondii carbonyl reductase 1, putative 0.0021 0.0013 0.0029
Echinococcus multilocularis Blood coagulation inhibitor, Disintegrin 0.0137 0.0589 0.0587
Entamoeba histolytica oxidoreductase, short chain dehydrogenase/reductase family 0.0021 0.0013 0.0081
Trichomonas vaginalis PIKK family atypical protein kinase 0.0024 0.0029 0.02
Mycobacterium ulcerans short chain dehydrogenase 0.0021 0.0013 0.0029
Entamoeba histolytica 3-ketodihydrosphingosine reductase protein, putative 0.0021 0.0013 0.0081
Plasmodium falciparum thioredoxin reductase 0.0038 0.0097 0.161
Mycobacterium ulcerans cytochrome P450 143A4 Cyp143A4 0.0033 0.0074 0.0181
Brugia malayi Isocitrate dehydrogenase 0.0053 0.0172 0.025
Loa Loa (eye worm) hypothetical protein 0.0027 0.0047 0.0054
Loa Loa (eye worm) thioredoxin reductase 0.0038 0.0097 0.0115
Loa Loa (eye worm) oxidoreductase 0.0021 0.0013 0.0014
Echinococcus multilocularis NADPH cytochrome P450 reductase 0.0026 0.0039 0.0037
Mycobacterium ulcerans pyruvate kinase 0.004 0.011 0.0273
Toxoplasma gondii aldehyde dehydrogenase 0.0194 0.087 0.2201
Loa Loa (eye worm) TOPoisomerase family member 0.0062 0.0219 0.0262
Mycobacterium tuberculosis Probable aldehyde dehydrogenase 0.0194 0.087 0.2201
Echinococcus granulosus lamin 0.017 0.0753 0.0751

Activities

Activity type Activity value Assay description Source Reference
Potency (functional) = 7.0795 um PUBCHEM_BIOASSAY: VP16 counterscreen qHTS for inhibitors of ROR gamma transcriptional activity. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) = 7.0795 um PUBCHEM_BIOASSAY: qHTS for inhibitors of ROR gamma transcriptional activity. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) 7.9433 uM PUBCHEM_BIOASSAY: qHTS Assay for Inhibitors of Histone Lysine Methyltransferase G9a. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID504404] ChEMBL. No reference
Potency (functional) = 10 um PUBCHEM_BIOASSAY: qHTS Assay for Inhibitors of Leishmania Mexicana Pyruvate Kinase (LmPK). (Class of assay: confirmatory) [Related pubchem assays: 1379 ] ChEMBL. No reference
Potency (functional) = 10 um PUBCHEM_BIOASSAY: qHTS Assay for Activators of Leishmania Mexicana Pyruvate Kinase (LmPK). (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) 14.1254 uM PubChem BioAssay. qHTS of Trypanosoma Brucei Inhibitors. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) 18.526 uM PUBCHEM_BIOASSAY: Primary qHTS for delayed death inhibitors of the malarial parasite plastid, 96 hour incubation. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID488745, AID488752, AID488774, AID504848, AID504850] ChEMBL. No reference
Potency (functional) = 19.9526 um PUBCHEM_BIOASSAY: qHTS Assay for Inhibitors of HPGD (15-Hydroxyprostaglandin Dehydrogenase). (Class of assay: confirmatory) [Related pubchem assays: 2429 (Confirmation qHTS Assay for Inhibitors of HPGD (15-Hydroxyprostaglandin Dehydrogenase)), 2407 (Probe Development Summary for Inhibitors of HPGD (15-Hydroxyprostaglandin Dehydrogenase)), 2427 (Thermal Shift Assay for Inhibitors of HPGD (15-Hydroxyprostaglandin Dehydrogenase))] ChEMBL. No reference
Potency (functional) 28.1838 uM PUBCHEM_BIOASSAY: qHTS Assay for Inhibitors of JMJD2A-Tudor Domain. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID504402] ChEMBL. No reference
Potency (functional) 44.6684 uM PubChem BioAssay. qHTS of PTHR Inhibitors: Primary Screen. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) = 79.4328 um PUBCHEM_BIOASSAY: qHTS Inhibitors of AmpC Beta-Lactamase (assay with detergent). (Class of assay: confirmatory) [Related pubchem assays: 1002 (Confirmation Concentration-Response Assay for Inhibitors of AmpC Beta-Lactamase (assay with detergent)), 585 (Promiscuous and Specific Inhibitors of AmpC Beta-Lactamase (assay without detergent) - a screen old NIH MLSMR collection), 584 (Promiscuous and Specific Inhibitors of AmpC Beta-Lactamase (assay with detergent) - a screen of the old NIH MLSMR collection), 1003 (Confirmation Cuvette-Based Assay for Inhibitors of AmpC Beta-Lactamase (assay with detergent))] ChEMBL. No reference
Potency (functional) 100 uM PubChem BioAssay. qHTS for Antagonist of cAMP-regulated guanine nucleotide exchange factor 3 (EPAC1): primary screen. (Class of assay: confirmatory) ChEMBL. No reference

Phenotypes

Whole-cell/tissue/organism interactions

Species name Source Reference Is orphan
Plasmodium falciparum ChEMBL23

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

Bibliographic References

No literature references available for this target.

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